Digital Commons Network^™

A Translocal Approach To Dialogue-Based Art, Rachelle Marie Viader Knowles

Other Faculty of Arts, Humanities and Business Theses

This thesis is a practice-led investigation into a translocal approach to dialogue-based art. The research has been undertaken through the practice of the ‘artist/academic’, drawing on my professional experience in artistic research, academic leadership and teaching, each informing my methods and findings. The problem which emerged through the practice is how to devise an approach to dialogue-based art that is responsive to twenty-first century social relations and telecommunications and attendant to the politics of mobility that constrain and control human movement. The research develops and tests out the application of ideas from the interdisciplinary field of translocality to the practice …

Dogs And Domesticity Reading The Dog In Victorian British Visual Culture, Amy Robson

Other Faculty of Arts, Humanities and Business Theses

The central aim of this thesis is to critically examine the values associated with dogs in Victorian British art and visual culture. It studies the redefining and restructuring of the domestic dog as it was conceptualized in visual culture and the art market. It proposes that the dog was strongly associated with social values and moral debates which often occurred within a visual arena, including exhibitions, illustrated newspapers, and prints. Consequently, visual representations of the dog can be seen as an important means through which to study Victorian culture and society. Historians have agreed that the Victorian period was a …

The Use Of Blogs For Teaching And Learning In Uk And Us Higher Education, Elaine Garcia

Other Faculty of Arts, Humanities and Business Theses

Within the last decade there has been a significant increase in the range of Social Media tools that have become available. This has led to a significant increase in the use and popularity of Social Media within many aspects of everyday life, particularly within the UK and US. One of the areas in which there has been a rise in the use of Social Media is within Higher Education (HE). Within HE there have been reports that Social Media has been successfully utilized for teaching and learning, particularly in the case of blogs. Despite reportedly successful usage there has to …

How Do Social Work Students Develop Their Professional Identity?, Julia Wheeler

Plymouth Institute of Education Theses

Professional socialisation is a key aspect of social work pre-qualifying training and the final practice placement has long been viewed as one of the most crucial elements of social work training, in enabling students to transfer learning on the course into practice (Parker, 2007). Whilst there has been substantial research into how students develop their skills in social work education, very few studies have focused upon the student’s development of professional identity and the process of professional socialisation (Valutis, Rubin and Bell, 2012). This study explores this gap, particularly the impact of the placement supervisor and agency context upon the …

Wearing Your Ethics: Investigating Consumer Purchase Intention Of Ethically Produced Fashion Products, Hannah E. Weiner

Theses and Dissertations

The aim of this paper is to contribute to the body of knowledge that exists in the area of ethical production by examining factors that influence purchase intention of ethically produced fashion products. The findings of this study provide a further understanding of ethical production by providing answers to the objectives. These results will also provide insight to firms wanting to effectively convey pro-environmental efforts to consumers. The findings may also assist marketers in understanding the consumers’ attitudes toward ethical manufacturing practices and their motivations for wearing their ethics and purchasing ethically produced fashion products.

The theoretical framework of this …

Patient Evaluation Of Emotional Comfort Experienced (Peece): Developing And Testing A Measurement Instrument, Anne Williams, Leanne Lester, Caroline Bulsara, Anna Petterson, Kellie Bennett, E Allen, David Joske

Nursing Papers and Journal Articles

Objectives: The Patient Evaluation of Emotional Comfort Experienced (PEECE) is a 12-item questionnaire which measures the mental well-being state of emotional comfort in patients. The instrument was developed using previous qualitative work and published literature.

Design: Instrument development.

Setting: Acute Care Public Hospital, Western Australia.

Participants: Sample of 374 patients.

Interventions: A multidisciplinary expert panel assessed the face and content validity of the instrument and following a pilot study, the psychometric properties of the instrument were explored.

Main outcome measures: Exploratory and confirmatory factor analysis assessed the underlying dimensions of the PEECE instrument; Cronbach’s α was used to determine the …

Management Pain And Anxiety In Endodontic Treatment, Andi Sumidarti, Wahyuni S. Dwiandhany

Journal of Dentomaxillofacial Science

No abstract provided.

Using Tcr Transgenic, Gp100 Reactive T Cells And Checkpoint Inhibition To Target Lymphangioleimyomatosis, Christian Ankney

Master's Theses

Lymphangioleiomyomatosis (LAM) is a low-grade neoplastic disease affecting primarily women. It is characterized by cystic lung disease as well as renal and retroperitoneal tumors called angiomyolipomas and lymphangiomas. Tumor cells have smooth muscle features as well as neuroendocrine cell surface markers, and the disease can be diagnosed by HMB45 staining of tumor cells. We questioned whether expression of melanocytic antigens, specifically gp100, creates an opportunity to treat LAM by adoptive T cell transfer. LAM lung lesions demonstrate poor immune surveillance, therefore adoptive T cell transfer could offer benefits in this disease.

A link was made between melanoma and depigmenting vitiligo …

Creating A Bret Assay To Monitor The Interaction Between Β-Arrestin-1 And Stam-1, James Buhrmaster

Master's Theses

CXCR4 is a chemokine receptor that is overexpressed in multiple disease states, including cancer. Understanding the mechanisms by which cells regulate CXCR4 expression is of high importance, as they can reveal downstream effectors that can potentially be targeted pharmacologically to more effectively treat diseases with fewer side effects.

CXCR4 is internalized in response to stimulation by its ligand CXCL12, and localizes to early endosomes as part of a homologous desensitization mechanism. From the endosome, CXCR4 can enter one of two pathways whereby it is either recycled back to the plasma membrane, where it can undergo another signaling event, or it …

Coping With Exposure To Community Violence: Assessing The Role Of Avoidance In Reducing Delinquency And Aggression In Low-Income Urban Adolescents, Cara Marie Diclemente

Master's Theses

Exposure to community violence has disabling effects on the mental health of youth in the US, with high rates of exposure for African American adolescents from underserved, urban communities. Past literature suggests that avoidant coping, specifically behavioral avoidance, may be most useful for youth exposed to uncontrollable stress. The current study assessed the utility of coping strategies in reducing aggression and delinquency in 267 sixth through eighth grade African American youth. First, confirmatory factor analyses revealed a three-factor structure of coping: cognitive approach, behavioral approach, and avoidance. Next, moderated moderation findings showed that for boys, avoidance and approach strategies increased …

Phenotyping Temperature-Sensitive Coronaviruses, Amani Eddins

Master's Theses

Coronaviruses (CoVs) can cause a range of symptoms; from a mild common cold to life threatening acute respiratory distress syndrome (ARDS) upon infection. These emerging viruses have the ability to be highly pathogenic and detrimental to the human population. Two prime examples of CoV emergence, SARS-CoV (Severe Acute Respiratory Syndrome) and MERS-CoV, (Middle Eastern Respiratory Syndrome), which exhibits the pandemic potential of emerging CoVs that gain human tropism. Given the increasing potential of an emerging CoV outbreak there is a state of urgency to develop vaccines that will help protect the human population against current and future circulating strains. The …

Utilizing Genetic Techniques To Identify Amino Acids Within The Putative Glycosyltransferase Sypq That Are Essential For Its Role In Biofilm Formation By Vibrio Fischeri, Mary Kathryn Flaherty

Master's Theses

The polysaccharide component of the V. fischeri biofilm is produced by proteins encoded by the symbiosis polysaccharide (syp) locus. The syp locus encodes 18 genes, six of which are putative glycosyltransferases (GTs). One of these GTs, sypQ, encodes a putative family 2 glycosyltransferase (GT-2). The mechanism by which SypQ facilitates biofilm formation is not yet understood. To uncover which specific residues are essential for the function of SypQ, I utilized Bioinformatics, site-directed mutagenesis, and random mutagenesis. The Bioinformatics identified putative GT-2 motifs in the SypQ primary sequence. The mutagenesis (both site-directed and random), identified five residues (D95, D151, S153, D236, …

Potential Efficacy Of Targeting Mll1 In Breast Cancer, Austin Gable Holmes

Master's Theses

In 2017, it is estimated that breast cancer will be the most prevalent newly diagnosed cancer in females, at 30% in the U.S. alone1. From the early 1990s to 2014 the death rate in females from breast cancer has dropped by 10% but still stands as the second highest cancer related death in females in the U.S.2. One of the biggest hurdles in breast cancer research is disease heterogeneity. New mechanisms of disease development and progression are encountered frequently. One mechanism studied in the past decades is epigenetics. It has been theorized that the cancer epigenome can maintain an abnormal …

Optimizing Clean Catch Urine Collection And Its Applications In Urinary Microbiome Studies, Danielle Johansen

Master's Theses

Clean catch was developed before the advancement of more sensitive assays for culturing urinary bacteria. I reassessed clean catch, endeavoring to optimize this method. Periurethral swabs and voided urines were routinely collected, while analyzing different aspects of the method. I determined that midstream urine contained the least amount of vulvo-vaginal contamination and that the time of collection did not impact the results. I also determined that the use of antiseptic wipes prior to void increased the level of vulvo-vaginal contamination. A small cohort of females collected daily urines over a 17-day period and kept a strict alcohol diary. Females who …

Fear Of Missing Out: A Moderated Mediation Approach To Social Media Use, Brynn M. Huguenel

Master's Theses

This study explores whether fear of missing out (FOMO) mediates the relation between social networking site (SNS) use and negative mental health outcomes, with moderators of Facebook activities and individual-level characteristics included. Short-term longitudinal data was collected from undergraduate students (N=296). Mediation analyses indicated that intensity of Facebook use did not predict anxiety or depression, as mediated by FOMO. Further, Facebook activities did not moderate the relation between intensity of Facebook use and FOMO, and social comparison and social connectedness did not moderate the relations between FOMO and negative mental health outcomes. Post-hoc analyses showed that social connectedness moderated the …

Perceived Partner Sexism And Stigma Consciousness: How 'Prince Charming' Undermines Relationship Satisfaction, Danielle Lauren Kellogg

Master's Theses

Perceived discrimination (outside of the relationship) relates to negative relationship outcomes, moderated by stigma consciousness (DeHart, 2017). Women who report higher (versus lower) levels of perceived partner benevolent sexism (i.e., perceptions of one's partner's endorsement of sexist attitudes) experience more negative relationship outcomes as well (Hammond & Overall, 2013; Hammond & Overall, 2014; Hammond & Overall, 2015). In addition, relationship partners adopt more traditional gender roles after becoming parents, which fosters benevolent sexism (Trillingsgaard, Baucom, & Heyman, 2014). In this study, married or cohabiting women with children were randomly assigned to either a sexism manipulation or control condition, prior to …

Functional Studies Of Novel Mosquito Stage-Specific Genes In The Malaria Parasite, Plasmodium Berghei., Kaitlyn Kiernan

Master's Theses

The development and survival of the malaria parasite Plasmodium within its mosquito vector is not very well understood. When the parasite is taken up by an Anopheles mosquito, it is exposed to digestive enzymes, reactive oxygen species, increasing pH, decreasing temperature, and a diverse microbial flora. Our lab is studying the adaptive mechanisms underlying parasite survival in this hostile environment, one of which is movement out of the midgut. In order to escape the midgut, the parasite develops into an elongated, motile form called the ookinete. I am investigating two genes, thioredoxin-like protein 1 (trxl-1) and subpellicular microtubule protein 1 …

Dexamethasone Treatment Effects On H3k27me3 Chromatin Organization Is Related To Nk Cell Immune Dysregulation, Michael Sarafeno Misale

Master's Theses

It is well-established that psychological stress reduces natural killer (NK) cell immune function. This reduction is mediated by stress-induced release of glucocorticoids (GC), which can suppress immune function. Associated with suppression of a particular immune function are GC induced histone-epigenetic marks. Histone-epigenetic marks are responsible for the organization and compartmentalization of genomes into transcriptionally active euchromatin domains that are localized to the interior of the nucleus. Transcriptionally silent heterochromatic domains are enriched with methylated epigenetic marks and are localized to the nuclear periphery. The purpose of this investigation was to assess the influence of GC on H3K27me3 chromatin organization by …

Developing Integral Ecologists: Description And Analysis Of The State Of Environmental Education At Jesuit High Schools In Light Of Religious Ecological Commitments And Science Education Research, Philip Nahlik Nahlik

Master's Theses

This research responds to numerous calls to focus more immediately and deeply on environmental education in the context of local communities. Jesuit high schools offer a rich network to study this movement, as schools with long histories of scholarly and moral concerns for forming students to think about and act on worldwide problems. The key research question is: How can science education research inform environmental education in these schools? The research methodology includes data collection and analysis of publicly-accessible website data, phone interviews with teachers, and a literature review of science education research. Recommendations are given for vertically aligning the …

Filling Pews, Speaking Truth: Pro-Life Ministry In A Liberal Catholic Parish, Jonathan Neidorf

Master's Theses

Scholars of the pro-life movement in the United States have extensively documented how pro-lifers in this country feel that their cause is embattled by society (Williams and Blackburn 1996; Maxwell 2002; Munson 2008). Other research argues that conservative Catholics tend to feel that their Church is swept up in an increasing liberalization in greater society, which serves to compromise core moral tenets of the faith (Leege 1988; Weaver and Appleby 1995; Wedam 1993). No thorough research exists examining how pro-life Catholics see their Church's and their parish's liberalism as directly suppressing their pro-life work. In this ethnographic study of a …

Multifunctional Regulatory T Cells From Human Umbilical Cord Blood And The Role Of Tumor Necrosis Factor In Immune Homeostasis, Alexander Nelson

Master's Theses

Regulatory T cells (Tregs) are required to suppress inflammation and prevent autoimmunity. During fetal development Tregs are crucial to maintain tolerance between mother and child. After birth, neonates require tolerance to avoid harmful immune responses to foreign antigens in food and allow colonization with commensal microbes. We demonstrate a propensity for T cells in human umbilical cord blood to differentiate into Tregs in response to antigen receptor stimulation ex vivo. Cord blood-derived Tregs potently suppress T cell proliferation, but also produce pro-inflammatory cytokines known to activate innate immune responses. These results suggest that antigen exposure during early life results in …

Domestic Violence Among Asian Indian Immigrant Women In The United States, Teuta Peja

Master's Theses

This study looks at how domestic violence is conceptualized by the research studies on

Asian Indian immigrant communities in the United States through different periods of time, and

how sociocultural factors are associated with domestic violence. Using the meta-synthesis

descriptive method, I analyzed and interpreted the findings of four research studies conducted

between 1995-2016 that included in-depth interviews with Asian Indian immigrant women who

experienced domestic violence. The analysis focuses on changes of the patterns of abuse, helping behavior, and leaving the abusive marriage as an option. The changes in U.S. domestic

violence legislation and policy regarding immigration and domestic …

Children's Exposure To Violence Across Contexts: Profiles Of Family, School, And Community Witnessing And Victimization, Catherine Mary Rice

Master's Theses

Children residing in low-income, urban neighborhoods are at a disproportionately higher risk of exposure to violence (ETV) across multiple contexts compared to their peers, including witnessing violence and direct victimization. The many negative effects of ETV are compounded when youth experience ETV across multiple settings and when these experiences are chronic. Despite this, much of the research on ETV during childhood focuses on a single form of violence (e.g., family victimization or witnessing community violence). The current study examines patterns of frequency of ETV, including witnessing and victimization, across family, school, and community contexts, using person-centered methods to elucidate the …

Characterization Of Inhibitory Molecules Produced By Lactobacillus Crispatus, Giuseppe Anthony Pistone

Master's Theses

Lactobacillus species are widely accepted as beneficial bacteria of the human microbiota1-8. Lactobacilli spp. are well documented to inhibit pathogens by production and secretion of hydrogen peroxide (H2O2), organic acids, and/or proteinaceous bacteriocins into their environment. Most research attributes bactericidal activity of cell free supernatant (CFS) to H2O2 and/or lactic acid. Here, I demonstrate that CFS from a clinical isolate of Lactobacillus crispatus contains a molecule(s) that inhibits uropathogenic Escherichia coli (UPEC) colony formation independently of H2O2 and organic acids. Physiologic concentrations of H2O2 and organic acids produced by L. crispatus do not inhibit UPEC colony formation. Incubation of UPEC …

Intersectional Stereotypes Of Race, Gender, And Facial Structure And Evaluative Judgments Of Leadership Ability And Workplace Fit, Avery Nichole Waklatsi

Master's Theses

Though the labor market is highly competitive and diverse, minority groups only hold 26.7%, of board positions, in companies on the Fortune 500 list (Alliance for Board Diversity Census, 2013). When tasked with hiring managers whom are presented with equivalent job qualifications, evaluators may rely on their subjective impressions in making an employment decision. The evaluator's subjective impressions may be informed by stereotypes of the groups to which applicants belong. The current study tests how stereotypes pertaining to race, gender, and facial structure inform evaluator judgments of managerial applicants' leadership ability and workplace fit. Leadership ability and workplace fit are …

Reference Intervals For Thyroid Stimulating Hormone And Free Thyroxine Derived From Neonates Undergoing Routine Screening For Congenital Hypothyroidism At A University Teaching Hospital In Nairobi, Kenya: A Cross Sectional Study, Geoffrey Omuse, Ali Kassim, Francis Kiigu, Ra'ana Hussain, Mary Limbe

Pathology, East Africa

Background: In order to accurately interpret neonatal thyroid function tests (TFTs), it is necessary to have population specific reference intervals (RIs) as there is significant variation across different populations possibly due to genetic, environmental or analytical issues. Despite the importance of RIs, globally there are very few publications on RIs for neonatal TFTs primarily due to ethical and technical issues surrounding recruitment of neonates for a prospective study. To the best of our knowledge, this is the first report from Africa on neonatal RIs for TFTs.

Methods: We used hospital based data largely derived from neonates attending the wellness clinic …

Whiter Shade Of Pale: Making The Case For Jewish Presence In The Multicultural Classroom, Daniel Ian Rubin

Research, Publications & Creative Work

Despite over 4,000 years of persecution, American Jews and antisemitism continue to be overlooked in university multicultural and social justice classroom discussions. This is due to many factors, such as the misconceptions that Jews are solely a religious group, are White and have completely assimilated into American culture, and are economically successful. Jews are a distinctive group in the United States who continue to experience racism and oppression. In order to validate the racism and discrimination of Jews in the United States, university multicultural and social justice programs must begin to discuss the issues pertaining to antisemitism.

Knowledge Of Polymath Walks, Talks, Makes Waves, Turns Into Deeds, Hamlet Isaxanli, Waqas Ahmed

Khazar Journal of Humanities and Social Sciences

In this interview, Hamlet Isaxanli shares his opinion on polymathy. What makes a polymath? Isaxanli stresses the importance of two factors: a person’s nature may lead him/her to an insatiable thirst for knowledge and the desire to explore different fields simultaneously. On the other hand, the education system encourages polymathy from the perspective of the richness and diversity of the high school curriculum. Isaxanli also goes into the relationship between math and poetry as well as the art-science-humanities connections. He then calls attention to Omar Khayyam, Nasr al-Din Tusi and some polymaths of the 20th century. Finally yet importantly, Isaxanli …

Perceptions Of Parental Child Homicide In English Popular Visual Culture 1800-1850, Margaret L. Arnot

SOLON Law, Crime and History (previously SOLON Crimes and Misdemeanours: Deviance and the Law in Historical Perspective)

This article discusses in depth several English illustrated broadsides produced in the first half of the nineteenth century and depicting child homicides. It provides the most detailed analysis to date of the complex interplay of illustration, verse and prose on murder sheets from the period. The cultural representations of homicides of children found in these broadsides contributed in important ways to understandings of culpability for the killings of infants and young children. Rather than simply illustrating the texts on the broadsides, the visual images amplified the emotional resonance of this medium, arguably increasing its effectiveness. In the hands of anonymous, …

Editorial: Solon Law, Crime And History Volume 7 No.1 2017, Kim Stevenson, Judith Rowbotham, Samantha Pegg

SOLON Law, Crime and History (previously SOLON Crimes and Misdemeanours: Deviance and the Law in Historical Perspective)

No abstract provided.