Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2017

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 62491 - 62520 of 62840

Full-Text Articles in Entire DC Network

The Relationship Between The Trendelenburg Position And Cerebral Hypoxia Inpatients Who Have Undergone Robot-Assisted Hysterectomy And Prostatectomy, Ali̇ Özgün, Asuman Sargin, Semra Karaman, İlkben Günüşen, Işik Alper, Fatma Zeki̇ye Aşkar Jan 2017

The Relationship Between The Trendelenburg Position And Cerebral Hypoxia Inpatients Who Have Undergone Robot-Assisted Hysterectomy And Prostatectomy, Ali̇ Özgün, Asuman Sargin, Semra Karaman, İlkben Günüşen, Işik Alper, Fatma Zeki̇ye Aşkar

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the relationship between the Trendelenburg position and cerebral hypoxia in robot-assisted hysterectomy and prostatectomy.Materials and methods: A standardized mini-mental state examination was administered to 50 patients enrolled in the study 1 h before and after surgery. Near infrared spectroscopy (NIRS) values and hemodynamic and respiratory parameters were recorded after induction of anesthesia (baseline) and once every 20 min in the Trendelenburg position and supine positions. The relationship between the development of cerebral desaturation and the patient's position was examined. Results: For all patients, the baseline mean cerebral oxygen saturation (RSO2) on the right and …

Go to article

Topographic Methods To Expose The Exiting Points Of Supratrochlear, Supraorbital, And Zygomaticotemporal Nerves, Mesut Sabri̇ Tezer, İsmai̇l Yağmurhan Gi̇lan, Özlem Elvan, Vedi̇a Bennu Özcömert, Mustafa Akteki̇n Jan 2017

Topographic Methods To Expose The Exiting Points Of Supratrochlear, Supraorbital, And Zygomaticotemporal Nerves, Mesut Sabri̇ Tezer, İsmai̇l Yağmurhan Gi̇lan, Özlem Elvan, Vedi̇a Bennu Özcömert, Mustafa Akteki̇n

Turkish Journal of Medical Sciences

Background/aim: We evaluated the relations of the exiting points of supratrochlear (STN), supraorbital (SON), and zygomaticotemporal (ZTN) nerves with certain landmarks to provide improved anatomic knowledge. Materials and methods: The twenty-eight hemifaces of 5 fresh frozen and 11 embalmed heads (5 female and 11 male cadavers) were dissected. Distance and angular measurements were made between the exiting points of the nerves to the midline, lateral, and medial canthi. Comparisons of side, sex, and cadaver groups were evaluated.Results: Mean values were determined for all parameters. There was no difference between side measurements. There were significant differences between sexes and cadaver groups …

Go to article

The Diagnostic Accuracy Of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (Ebus-Tbna) In Mediastinal Tuberculous Lymphadenitis, Onur Fevzi̇ Erer, Serhat Erol, Ceyda Anar, Can Bi̇çmen, Zeki̇ye Aydoğdu, Seri̇r Özkan Jan 2017

The Diagnostic Accuracy Of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (Ebus-Tbna) In Mediastinal Tuberculous Lymphadenitis, Onur Fevzi̇ Erer, Serhat Erol, Ceyda Anar, Can Bi̇çmen, Zeki̇ye Aydoğdu, Seri̇r Özkan

Turkish Journal of Medical Sciences

Background/aim: Mediastinal lymph nodes are the second most commonly affected lymph nodes in tuberculous lymphadenitis. It is often difficult to diagnose tuberculosis in patients with lymphadenopathy without parenchymal lesions. The aim of this study was to describe the diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with isolated mediastinal tuberculous lymphadenitis (MTLA). Materials and methods: This study included 527 patients who had undergone EBUS-TBNA between December 2012 and December 2014. Patients with the final diagnosis of MTLA were evaluated. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of EBUS-TBNA were calculated.Results: The …

Go to article

Three-Dimensional Evaluation Of Pelvic Posture In Adolescents With And Without A History Of Low Back Pain, Seher Özyürek, Arzu Genç, Hayri̇ye Kul Karaali̇, Zeli̇ha Candan Algun Jan 2017

Three-Dimensional Evaluation Of Pelvic Posture In Adolescents With And Without A History Of Low Back Pain, Seher Özyürek, Arzu Genç, Hayri̇ye Kul Karaali̇, Zeli̇ha Candan Algun

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the three-dimensional (3D) profile of pelvic posture and postural displacements of the pelvis in adolescents with and without a history of low back pain (LBP). Materials and methods: Thirty-two adolescents participated in this study. Participants were asked if they had ever suffered LBP at some point in their lives. Participants were divided into two groups: with a history of LBP (LBP group) and without a history of LBP (control group). For 3D evaluation of pelvic posture, the PosturePrint system was used. Three digital photographs were obtained in an upright stance (anteroposterior, left-right lateral) and …

Go to article

Adaptation, Reliability, And Validity Study Of The Hwalek-Sengstockelder Abuse Screening Test (H-S/East): A Turkish Version, Ni̇lgün Özçakar, Akça Toprak Ergönen, Mehtap Kartal, Hakan Baydur Jan 2017

Adaptation, Reliability, And Validity Study Of The Hwalek-Sengstockelder Abuse Screening Test (H-S/East): A Turkish Version, Ni̇lgün Özçakar, Akça Toprak Ergönen, Mehtap Kartal, Hakan Baydur

Turkish Journal of Medical Sciences

Background/aim: The most important issues in elder abuse and neglect are lack of awareness and difficulties in determining the situation. Our aim is to determine the reliability and validity of the Turkish version of the Hwalek-Sengstock Elder Abuse Screening Test (H-S/EAST).Materials and methods: The H-S/EAST (15-itemed, three-dimensional: direct abuse, characteristics of vulnerability, and potentially abusive situation) was translated according to the guidelines and experts evaluated it for content validity and cultural adaptation. Participants' (n = 252) mean age was 73.4 ± 6.4 years and 58.3% were female. The World Health Organization Quality of Life Instrument-Older Adults Module (WHOQOL-OLD) and the …

Go to article

Isolation And Culture Of Adult Mouse Vestibular Nucleus Neurons, Aydin Hi̇m, Serap Altuntaş, Gürkan Öztürk, Ender Erdoğan, Nureddi̇n Cengi̇z Jan 2017

Isolation And Culture Of Adult Mouse Vestibular Nucleus Neurons, Aydin Hi̇m, Serap Altuntaş, Gürkan Öztürk, Ender Erdoğan, Nureddi̇n Cengi̇z

Turkish Journal of Medical Sciences

Background/aim: Isolated cell cultures are widely used to study neuronal properties due to their advantages. Although embryonic animals are preferred for culturing, their morphological or electrophysiological properties may not reflect adult neurons, which may be important in neurodegenerative diseases. This paper aims to develop a method for preparing isolated cell cultures of medial vestibular nucleus (MVN) from adult mice and describe its morphological and electrophysiological properties.Materials and methods: Vestibular nucleus neurons were mechanically and enzymatically isolated and cultured using a defined medium with known growth factors. Cell survival was measured with propidium iodide, and electrophysiological properties were investigated with current-clamp …

Go to article

Histopathological Effects Of Mesenchymal Stem Cells In Ratswith Bladder And Posterior Urethral Injuries, Berat Di̇lek Demi̇rel, Ünal Biçakci, Riza Rizalar, Ferda Alpaslan Pinarli, Oğuz Aydin Jan 2017

Histopathological Effects Of Mesenchymal Stem Cells In Ratswith Bladder And Posterior Urethral Injuries, Berat Di̇lek Demi̇rel, Ünal Biçakci, Riza Rizalar, Ferda Alpaslan Pinarli, Oğuz Aydin

Turkish Journal of Medical Sciences

Background/aim: To evaluate the effects of mesenchymal stem cell (MSC) therapy in an experimental bladder and posterior urethral injury model. Materials and methods: The study subjects consisted of 40 male Wistar albino rats that were divided into four groups: control group (n = 10) (the bladder was only surgically opened and closed), sham group (n = 10) (surgical procedure), IVMSC group (n= 10) (surgical procedure and intravenous MSC treatment), and LMSC group (n = 10) (surgical procedure and local MSC treatment). Histopathological evaluation was performed for the degree of fibrosis and inflammation and the extent and intensity of staining of …

Go to article

The Reno-Protective Effects Of Atorvastatin In Crush Syndrome And Rhabdomyolysis:Is There A Dilemma?, Demet Acar, Mustafa Gülpembe, Can Gökay Yildiz, Emi̇ne Nur Özdamar, Kerem Açikgöz, Ahmet Çağlar, Başar Cander Jan 2017

The Reno-Protective Effects Of Atorvastatin In Crush Syndrome And Rhabdomyolysis:Is There A Dilemma?, Demet Acar, Mustafa Gülpembe, Can Gökay Yildiz, Emi̇ne Nur Özdamar, Kerem Açikgöz, Ahmet Çağlar, Başar Cander

Turkish Journal of Medical Sciences

Background/aim: We aim to determine the effects of low-dose atorvastatin treatment together with crush fluid resuscitation on renal functions and muscle enzyme levels in a rat model of crush syndrome. Materials and methods: The study involved female Wistar Albino rats weighing 250-300 g that were housed with free access to food and water. The crush model was obtained by compression. Rats were randomly divided into four groups: control (C) group, atorvastatin + crush fluid (ACF) group, crush fluid (CF) group, and hypertonic saline (%3) + mannitol + sodium bicarbonate (SM) group. Blood was obtained at 24, 48, and 72 h, …

Go to article

Chromosomal Findings And Sequence Analysis Of Target Exons Of Calcium-Sensingreceptor (Casr) Gene In Patients With Sagliker Syndrome, Erdal Tunç, Osman Demi̇rhan, Yahya Sağliker, İsmai̇l Yildiz, Nuray Paylar, Ali̇ İrfan Güzel Jan 2017

Chromosomal Findings And Sequence Analysis Of Target Exons Of Calcium-Sensingreceptor (Casr) Gene In Patients With Sagliker Syndrome, Erdal Tunç, Osman Demi̇rhan, Yahya Sağliker, İsmai̇l Yildiz, Nuray Paylar, Ali̇ İrfan Güzel

Turkish Journal of Medical Sciences

Background/aim: Sagliker syndrome (SS) develops as a continuation of chronic kidney disease and secondary hyperparathyroidism conditions. It was thought that there are some genetic predisposition factors leading to SS. The calcium-sensing receptor (CaSR) is essential for calcium homeostasis in the body. We aimed to examine SS patients for chromosome aberrations (CAs) and CaSR gene abnormalities in exons 2 and 3. Materials and methods: Twenty-three patients and 23 control subjects were admitted to Balcalı Hospital of the Medical Faculty of Çukurova University in Turkey between 2009 and 2011. Chromosomal analysis was performed according to standard cytogenetic methods. Full sequencing of exons …

Go to article

Pooled Analysis Of 899 Nosocomial Meningitis Episodes From Turkey, Oğuz Reşat Si̇pahi̇, Arzu Nazli Zeka, Meltem Taşbakan, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Tansu Yamazhan, Hi̇lal Si̇pahi̇, Sercan Ulusoy Jan 2017

Pooled Analysis Of 899 Nosocomial Meningitis Episodes From Turkey, Oğuz Reşat Si̇pahi̇, Arzu Nazli Zeka, Meltem Taşbakan, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Tansu Yamazhan, Hi̇lal Si̇pahi̇, Sercan Ulusoy

Turkish Journal of Medical Sciences

Background/aim: Healthcare-associated meningitis (HCAM) is a relatively rare entity with significant morbidity and mortality. The aim of this study was to systematically review the Turkish medical literature for acute nosocomial meningitis. Materials and methods: One national (ULAKBİM) and two international (www.scopus.com and www.pubmed.com) databases were searched. In addition, abstracts of four national congresses held between 2004 and 2013 were searched for reports for HCAM meningitis. Results: Data for 899 HCAM meningitis episodes were obtained from 24 reports. In terms of clinical findings, 177 of 216 (81.9%) had fever (>38 °C), 55 of 64 (85.9%) had high CRP levels, 105 …

Go to article

Is There Any Difference In Tetanus Igg Levels Of Diabetic Patientswith Respect To The Presence Of Foot Ulcers?, Fati̇h Teki̇n, Mehmet Sürmeli̇, Zeynep Çi̇zmeci̇, Özlem Teki̇n, Ergi̇n Işik, Ömer Faruk Taner, Derun Taner Ertuğrul Jan 2017

Is There Any Difference In Tetanus Igg Levels Of Diabetic Patientswith Respect To The Presence Of Foot Ulcers?, Fati̇h Teki̇n, Mehmet Sürmeli̇, Zeynep Çi̇zmeci̇, Özlem Teki̇n, Ergi̇n Işik, Ömer Faruk Taner, Derun Taner Ertuğrul

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to reveal the tetanus immunization status of diabetic patients and to determine whether diabetic patients with foot ulcers have different TIG levels. Materials and methods: A cross-sectional study was designed that included diabetic patients with foot ulcers (n = 30) and diabetic patients without ulcers (n = 30). The groups were compared for serum TIG levels along with total serum protein, albumin, C-reactive protein (CRP), and total immunoglobulin G (Ig G). Results: For diabetic patients without foot ulcers, 17 of 30 (56.6%) patients were found to have nonprotective TIG levels whereas for diabetic …

Go to article

Potential Drug-Drug Interactions Among Prescriptionsfor Elderly Patients In Primary Health Care, Zafer Gören, Mahluga J. Demirkapu, Gökçe Akpinar Acet, Sanda Çali, Medine Gülçebi̇ İdri̇z Oğlu Jan 2017

Potential Drug-Drug Interactions Among Prescriptionsfor Elderly Patients In Primary Health Care, Zafer Gören, Mahluga J. Demirkapu, Gökçe Akpinar Acet, Sanda Çali, Medine Gülçebi̇ İdri̇z Oğlu

Turkish Journal of Medical Sciences

Background/aim: Elderly patients are at high risk from drug-drug interactions (DDIs). This study evaluates the potential DDIs in Turkish elderly patients at a primary health care outpatient clinic. Materials and methods: Online database systems were used to examine DDIs on the prescriptions of patients (n = 1206). The clinical severity of DDIs was classified by the Lexi-Interact Online database. Results: Of the 5059 prescriptions, 33% were found to have DDIs. We detected 29 (0.9%) A, 380 (11.8%) B, 2494 (77.7%) C, 289 (9%) D, and 18 (0.6%) X risk rating category DDIs among the prescriptions. Prescriptions of female patients and …

Go to article

Sex-Related Differences In Copd Assessment Test Scores Of Copd Populationswith Or Without Significant Anxiety And/Or Depression, Yelda Varol, Ceyda Anar, Pinar Çi̇men, Mehmet Ünlü, Hüseyi̇n Hali̇lçolar, Sali̇h Zeki̇ Güçlü Jan 2017

Sex-Related Differences In Copd Assessment Test Scores Of Copd Populationswith Or Without Significant Anxiety And/Or Depression, Yelda Varol, Ceyda Anar, Pinar Çi̇men, Mehmet Ünlü, Hüseyi̇n Hali̇lçolar, Sali̇h Zeki̇ Güçlü

Turkish Journal of Medical Sciences

Background/aim: Sex-related differences have not been thoroughly explored in chronic obstructive pulmonary disease (COPD). We aimed to evaluate possible sex-related differences in COPD Assessment Test (CAT) scores of COPD patients with or without significant anxiety and/or depression. Materials and methods: Stable COPD patients were prospectively enrolled in the study between July 2013 and April 2014. Levels of anxiety, depression, dyspnea, and health-related quality of life parameters were assessed using specific questionnaires, including the CAT and others. Demographic and clinical data were recorded and physiological tests were performed. All the data were compared to determine any sex-related differences. Results: A total …

Go to article

Relation Of Unsupported And Unsupervised Exercise With Anthropometric And Biochemical Indices Among Type 2 Diabetic Patients, Prince Chikwere, Kwabena Nsiah, Marina Tandoh Jan 2017

Relation Of Unsupported And Unsupervised Exercise With Anthropometric And Biochemical Indices Among Type 2 Diabetic Patients, Prince Chikwere, Kwabena Nsiah, Marina Tandoh

Turkish Journal of Medical Sciences

Background/aim: Type 2 diabetes is a lifestyle-related condition. Lifestyle modification in the management of type 2 diabetes incorporates exercise. The aim of this study was to find out how unsupported and unsupervised exercise relates to anthropometric indices and biochemical indices in type 2 diabetes patients. Materials and methods: In the cross-sectional study, a structured questionnaire was used to access data on the exercise history of patients. Subjects were classified according to exercise intensity. The dietary intake of patients was obtained by 24-h recall. Standard measurements were taken of waist circumference and blood pressure. Blood samples were also collected to measure …

Go to article

Abdominal Actinomycosis In The Last 10 Years And Risk Factors For Appendiceal Actinomycosis: Review Of The Literature, Marta Lisa-Gracia, Berta Martín-Rivas, Marcos Pajaron-Guerrero, Ana Arnaiz-García Jan 2017

Abdominal Actinomycosis In The Last 10 Years And Risk Factors For Appendiceal Actinomycosis: Review Of The Literature, Marta Lisa-Gracia, Berta Martín-Rivas, Marcos Pajaron-Guerrero, Ana Arnaiz-García

Turkish Journal of Medical Sciences

Background/aim: Actinomycosis is a granulomatous disease caused by filamentous, gram-positive, anaerobic bacteria. Actinomycetes are commensal inhabitants of the oral cavity and intestinal tract but acquire pathogenicity through invasion of breached or necrotic tissue. In abdominal actinomycosis (AA), the appendix and ileocecal region are usually involved. The aim of this study was to characterize patients diagnosed with AA and to establish the risk factors for appendiceal actinomycosis, including a short review of the literature. Materials and methods: We conducted a prospective cohort study of all patients diagnosed with AA in the University Hospital Marques de Valdecilla (Santander-Cantabria) from January 2003 to …

Go to article

Cardiac Mri And 3d Contrast-Enhanced Mr Angiography In Pediatric And Young Adult Patients With Turner Syndrome, Hasan Yi̇ği̇t, Aşan Önder, Senem Özgür, Zehra Aycan, Selmi̇n Karademi̇r, Vehbi̇ Doğan Jan 2017

Cardiac Mri And 3d Contrast-Enhanced Mr Angiography In Pediatric And Young Adult Patients With Turner Syndrome, Hasan Yi̇ği̇t, Aşan Önder, Senem Özgür, Zehra Aycan, Selmi̇n Karademi̇r, Vehbi̇ Doğan

Turkish Journal of Medical Sciences

Background/aim: This study aimed to describe the spectrum and frequency of cardiovascular abnormalities in pediatric and young adult patients with Turner syndrome (TS) using cardiac MRI and MR angiography. Materials and methods: This prospective study consisted of 47 female patients of pediatric age and young adults with a karyotypically confirmed diagnosis of TS. All patients underwent cardiac MRI and contrast-enhanced MR angiography. A second examination after 9-26 months was performed for 28 of these patients. Results: Elongation of the transverse aortic arch (ETA) was the most frequent abnormality with a rate of 37%. The rate of partial anomalous pulmonary venous …

Go to article

Factors Associated With The Rate Of Copd Exacerbations That Require Hospitalization, Radisa Pavlovic, Srdjan Stefanovic, Zorica Lazic, Slobodan Jankovic Jan 2017

Factors Associated With The Rate Of Copd Exacerbations That Require Hospitalization, Radisa Pavlovic, Srdjan Stefanovic, Zorica Lazic, Slobodan Jankovic

Turkish Journal of Medical Sciences

Background/aim: Exacerbations are key events in chronic obstructive pulmonary disease (COPD). Frequent exacerbations occurring during the natural course of COPD lead to deterioration of health-related quality of life and are major causes of morbidity and mortality. The aim of this study was to identify factors independently associated with frequent severe exacerbations of COPD that require hospitalization. Materials and methods: A case-control study was performed to analyze risk factors and frequency of severe exacerbations, which were defined by the GOLD guideline criteria. Stepwise multivariate regression was used to determine the significant predictors of frequent exacerbations. Results: Results revealed five independent predictors …

Go to article

Qf-Pcr In Invasive Prenatal Diagnosis: A Single-Center Experience In Turkey, Özge Özer Kaya, Altuğ Koç, Taha Reşi̇d Özdemi̇r, Özgür Kirbiyik, Berk Özyilmaz, Mehmet Özeren, Deni̇z Can Özteki̇n, Cüneyt Eftal Taner, Yaşar Beki̇r Kutbay Jan 2017

Qf-Pcr In Invasive Prenatal Diagnosis: A Single-Center Experience In Turkey, Özge Özer Kaya, Altuğ Koç, Taha Reşi̇d Özdemi̇r, Özgür Kirbiyik, Berk Özyilmaz, Mehmet Özeren, Deni̇z Can Özteki̇n, Cüneyt Eftal Taner, Yaşar Beki̇r Kutbay

Turkish Journal of Medical Sciences

Background/aim: QF-PCR has been used for more than 20 years. It is based on investigation of polymorphic short tandem repeats (STRs) and is widely used for prenatal rapid aneuploidy detection. Materials and methods: We report retrospectively our prenatal diagnosis results between January 2012 and May 2014 in Tepecik Training and Research Hospital Genetic Diagnostic Center. Prenatal diagnosis was recommended in 6800 high-risk pregnancies and 2883 patients agreed to invasive diagnosis. Chromosome analysis and QF-PCR were performed in all patients. Results: Normal results were reported in 2711 cases by fetal karyotyping and in 2706 cases by QF-PCR. Anomaly detection rates were …

Go to article

Fecal Carriage Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli And Klebsiella Spp. In A Turkish Community, Derya Çakir Erdoğan, Füsun Cömert, Eli̇f Aktaş Sepetci̇, Fürüzan Köktürk, Canan Külah Jan 2017

Fecal Carriage Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli And Klebsiella Spp. In A Turkish Community, Derya Çakir Erdoğan, Füsun Cömert, Eli̇f Aktaş Sepetci̇, Fürüzan Köktürk, Canan Külah

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine the prevalence of fecal carriage of extended-spectrum beta-lactamase (ESBL)-producing bacteria, enzyme types, and risk factors affecting colonization. Materials and methods: A total of 576 stool samples from outpatients were examined between October 2012 and May 2013. Screening was done with selective EMB plates. ESBL were detected by double-disk synergy and confirmed agar strip gradient methods. Enzyme types were determined by PCR. Results: The prevalence of fecal carriage was found as 30% (173 of 576). Recent use of antibiotics, hospitalization and surgical operation, diabetes, crowded household populations, and old age were associated …

Go to article

Epidemiology And Molecular Characteristics Of Methicillin-Resistantstaphylococcus Aureus From Skin And Soft Tissue Infections In Shiraz, Iran, Samira Mehrshad, Masoud Haghkhah, Shahin Aghaei Jan 2017

Epidemiology And Molecular Characteristics Of Methicillin-Resistantstaphylococcus Aureus From Skin And Soft Tissue Infections In Shiraz, Iran, Samira Mehrshad, Masoud Haghkhah, Shahin Aghaei

Turkish Journal of Medical Sciences

Background/aim: Panton-Valentine leukocidin (PVL)-positive methicillin-resistant Staphylococcus aureus (MRSA) infections are increasing in some regions of Iran. The aim of the current study was to assess the epidemiology and molecular characteristics of S. aureus isolated from patients with skin infections in Shiraz, Iran. Materials and methods: Swab samples were obtained from patients admitted to the skin and burn units of hospitals. The medical records of each patient were collected via questionnaire. All staphylococcal isolates were collected and examined by conventional methods for detecting S. aureus strains. PCR was used to detect S. aureus harboring the mecA and pvl genes. Results: Out …

Go to article

The Prevalence Of Coronary Artery Anomalies With Coronary Computed Tomography, Hakki Yeşi̇lyurt, Uğur Aksu, Kamuran Kalkan, Seli̇m Topcu, Enbi̇ya Aksakal, İbrahi̇m Hali̇l Tanboğa, Recep Sade, Fati̇h Rifat Ulusoy, Abdulmeci̇t Kantarci Jan 2017

The Prevalence Of Coronary Artery Anomalies With Coronary Computed Tomography, Hakki Yeşi̇lyurt, Uğur Aksu, Kamuran Kalkan, Seli̇m Topcu, Enbi̇ya Aksakal, İbrahi̇m Hali̇l Tanboğa, Recep Sade, Fati̇h Rifat Ulusoy, Abdulmeci̇t Kantarci

Turkish Journal of Medical Sciences

Background/aim: In this study, the aim is to investigate the prevalence of various coronary artery anomalies (CAAs), evaluated by 256-detector row coronary computed tomography (CCT), within the Turkish population. Materials and methods: We included 2973 patients who had received CCT. The high take-off right coronary artery (RCA) and left coronary artery (LCA), the RCA arising from the left sinus (LS), the LCA arising from the right sinus (RS), the circumflex artery (CX) arising from the RS, the single coronary ostium originating from the RS, the CX arising from the RCA, and the RCA arising from the pulmonary artery were evaluated. …

Go to article

Hpv Types And E6/E7 Mrna Expression In Cervical Samples From Turkish Women With Abnormal Cytology In Ankara, Turkey, İpek Tüney, Ayli̇n Altay, Koray Ergünay, Sevgen Çeli̇k Önder, Alp Usubütün, Mehmet Coşkun Salman, Gülendam Bozdayi, Erdem Karabulut, Osman Seli̇m Badur, Kunter Yüce, Ahmet Pinar Jan 2017

Hpv Types And E6/E7 Mrna Expression In Cervical Samples From Turkish Women With Abnormal Cytology In Ankara, Turkey, İpek Tüney, Ayli̇n Altay, Koray Ergünay, Sevgen Çeli̇k Önder, Alp Usubütün, Mehmet Coşkun Salman, Gülendam Bozdayi, Erdem Karabulut, Osman Seli̇m Badur, Kunter Yüce, Ahmet Pinar

Turkish Journal of Medical Sciences

Background/aim: Human papillomaviruses have been established as a risk factor for invasive carcinoma of the uterine cervix. HPV E6/E7 oncogene expression has recently emerged as a promising biomarker to determine the risk for progression to high-grade cervical lesions. The aim of this study was to evaluate HPV mRNA and DNA detection in samples with abnormal cytology. Materials and methods: Cervical specimens were obtained at the Department of Obstetrics and Gynecology via cervical brushes during January-October 2011. Liquid-based cytology slides were evaluated according to the 2001 Bethesda System. Cytology specimens from a total of 81 women with abnormal cytology were included. …

Go to article

Surveillance Of Preventive Measures For Ventilator Associated Pneumonia (Vap) And Its Rate In Makkah Region Hospitals, Saudi Arabia, Ahmad Banjar, Mohammed Felemban, Khalid Dhafar, Zohair Gazzaz, Badr Al Harthi, Mukhtiar Baig, Kasim Al Khatib, Jameela Zakaria, Kawther Hawsawi, Lilma Isahac, Arbi Akbar Jan 2017

Surveillance Of Preventive Measures For Ventilator Associated Pneumonia (Vap) And Its Rate In Makkah Region Hospitals, Saudi Arabia, Ahmad Banjar, Mohammed Felemban, Khalid Dhafar, Zohair Gazzaz, Badr Al Harthi, Mukhtiar Baig, Kasim Al Khatib, Jameela Zakaria, Kawther Hawsawi, Lilma Isahac, Arbi Akbar

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to assess the VAP rate and to identify VAP prevention activities in public sector hospitals situated in the Makkah Region, Saudi Arabia (SA). Materials and methods: In this cross-sectional study, the VAP data from 13 public sector hospitals were collected from January to December 2013 and analyzed using SPSS 16. Results: The overall VAP rate in Makkah Region hospitals was 6.89 cases per 1000 ventilator-days. There was a significant difference in VAP rate among the hospitals of the Makkah Region (P < 0.001). There was no significant difference in the VAP rate among hospitals, which were using only one, two, or all three VAP preventive approaches (P = 0.26) accredited by the Joint Commission International (JCI) and Central Board for Accreditation of Health Care Institution (CBAHI) (P = 0.12), and using the form in intensive care units (ICUs) (P = 0.85). There was a significant difference in the VAP rate among hospitals having different bed capacities (P < 0.001), data regularly collected (P = 0.03), and had a team to supervise the VAP project (P = 0.04). Conclusion: The VAP rate in Makkah Region hospitals is 6.89 cases per 1000 ventilator-days.

Go to article

A Novel Mutation In Exon 1 Of Gata4 In Egyptian Patients With Congenital Heart Disease, Olfat Shaker, Salwa Omran, Eman Sharaf, Gehan A. Hegazy, Mohamed Mashaly, Nagwa E.A. Gaboon Jan 2017

A Novel Mutation In Exon 1 Of Gata4 In Egyptian Patients With Congenital Heart Disease, Olfat Shaker, Salwa Omran, Eman Sharaf, Gehan A. Hegazy, Mohamed Mashaly, Nagwa E.A. Gaboon

Turkish Journal of Medical Sciences

Background/aim: Congenital heart disease (CHD) is a common birth defect. Many studies have reported GATA4 mutations in patients with CHD, mainly septal defects. This study aimed to investigate the GATA4 exon 1 mutation in Egyptian patients with isolated congenital heart defects as a possible causative mutation. Materials and methods: Screening for mutations or any sequence variations in exon 1 of the GATA4 gene was carried out by PCR amplification followed by direct sequencings in 165 Egyptian patients with different nonsyndromic congenital heart diseases and 93 controls who were matched in terms of age and sex. Thorough clinical assessments were done …

Go to article

Physicochemical And Biochemical Parameters In Milk Of Serbian Breastfeeding Women, Slavica Sunaric, Marko Denic, Jelena Lalic, Tatjana Jovanovic, Ana Spasic, Jelena Zivkovic, Natasa Trutic, Gordana Kocic Jan 2017

Physicochemical And Biochemical Parameters In Milk Of Serbian Breastfeeding Women, Slavica Sunaric, Marko Denic, Jelena Lalic, Tatjana Jovanovic, Ana Spasic, Jelena Zivkovic, Natasa Trutic, Gordana Kocic

Turkish Journal of Medical Sciences

Background/aim: This study was undertaken to determine the changes and relationships between some important milk constituents as well as physical, rheological, and biochemical parameters of milk obtained from Serbian breastfeeding mothers. Materials and methods: Physicochemical and biochemical parameters and the concentrations of vitamins, uric acid, and minerals were determined during the three periods of lactation covering colostrum, transitional, and mature milk collected from 67 mothers who had a term-pregnancy. Results: Large interindividual variations regarding many parameters were found between mothers at the same period of lactation, but the average values were mostly in the expected and recommended ranges. For some …

Go to article

Identification Of The Cysteine-Rich 61 (Cyr61) Gene Variations In Osteosarcoma Patients, Syed Rizwan Hussain, Sabir Ali, Ajai Singh, Vineet Kumar, Nazia Rizivi, Manish Yadav, Mohammad Kaleem Ahmad, Vijay Kumar, Abbas Ali Mahdi Jan 2017

Identification Of The Cysteine-Rich 61 (Cyr61) Gene Variations In Osteosarcoma Patients, Syed Rizwan Hussain, Sabir Ali, Ajai Singh, Vineet Kumar, Nazia Rizivi, Manish Yadav, Mohammad Kaleem Ahmad, Vijay Kumar, Abbas Ali Mahdi

Turkish Journal of Medical Sciences

Background/aim: Osteosarcoma requires an angiogenesis process. CYR61 is one of the extracellular signaling molecules that promote angiogenesis, tumor growth, and the malignancy of osteosarcoma. In the present study, we investigate the CYR61 gene variations in osteosarcoma and their correlations with clinicopathological findings. Materials and methods: We performed variation analysis of the CYR61 gene in 58 patients with osteosarcoma. With an aim to ascertain the variety of variations in exons 2, 3, 4, and 5 of the CYR61 gene in osteosarcoma, we did a PCR-SSCP followed by DNA sequencing. Results: In osteosarcoma the CYR61 gene variations found were 18.96% (11/58) in …

Go to article

Effects Of Steep Trendelenburg Position And Pneumoperitoneum On Middleear Pressure In Patients Undergoing Robotic Radical Prostatectomy, Füsun Bozkirli, Nurdan Bedi̇rli̇, Mehmet Akçabay Jan 2017

Effects Of Steep Trendelenburg Position And Pneumoperitoneum On Middleear Pressure In Patients Undergoing Robotic Radical Prostatectomy, Füsun Bozkirli, Nurdan Bedi̇rli̇, Mehmet Akçabay

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to quantify the changes in middle ear pressure (MEP) during robot-assisted radical prostatectomy (RARP). Materials and methods: Thirty patients undergoing RARP were included in this study. MEP was obtained at the following time points: awake (T1), postintubation (T2), pneumoperitoneum + 1 h of Trendelenburg position (T3), pneumoperitoneum + 2 h of Trendelenburg position (T4), pneumoperitoneum + 3 h of Trendelenburg position (T5), desufflation + supine position (T6), and 1 h after extubation in the postanesthesia care unit (T7). Heart rate, mean arterial pressure (MAP), peak airway pressure (PAP), tidal volume, minute ventilation, EtCO2, …

Go to article

Is Lower Uterine Segment Involvement A Prognostic Factor In Endometrial Cancer?, Sali̇m Erkaya, Murat Öz, Hasan Onur Topçu, Ali̇ Levent Şi̇rvan, Tayfun Güngör, Mehmet Mutlu Meydanli Jan 2017

Is Lower Uterine Segment Involvement A Prognostic Factor In Endometrial Cancer?, Sali̇m Erkaya, Murat Öz, Hasan Onur Topçu, Ali̇ Levent Şi̇rvan, Tayfun Güngör, Mehmet Mutlu Meydanli

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study is to investigate the prognostic significance of lower uterine segment (LUS) involvement in endometrial cancer (EC). Materials and methods: We reviewed the patients who were operated at our institution between July 2007 and March 2015 with the diagnosis of EC. Tumors localized in the corpus and involving the LUS or localized entirely in the LUS formed Group A, while tumors in the uterine corpus without LUS involvement formed Group B. Clinicopathological characteristics and survival of the patients were compared in both groups. Results: A total of 500 patients were included in the study. There …

Go to article

Outcomes After Lobectomy And Pneumonectomy In Lungcancer Patients Aged 70 Years Or Older, İlknur Ayteki̇n, Maruf Şanli, Ahmet Ferudun Işik, Bülent Tunçözgür, Ahmet Uluşan, Kemal Bakir, Seval Kul, Levent Elbeyli̇ Jan 2017

Outcomes After Lobectomy And Pneumonectomy In Lungcancer Patients Aged 70 Years Or Older, İlknur Ayteki̇n, Maruf Şanli, Ahmet Ferudun Işik, Bülent Tunçözgür, Ahmet Uluşan, Kemal Bakir, Seval Kul, Levent Elbeyli̇

Turkish Journal of Medical Sciences

Background/aim: For the early stage of nonsmall-cell lung cancer, surgical resection provides the best survival, but the surgical risk generally increases with age because of the increased prevalence of comorbidities, especially cardiovascular disorders. The aim of this study was to compare survival and mortality rates of two groups with different ages, younger and older than 70 years, who went curative resection for nonsmall-cell lung cancer. Materials and methods: We analyzed the patients who underwent curative lung cancer surgery in the Department of Thoracic Surgery of Gaziantep University Research Hospital between January 1997 and November 2014. Patients were divided into 2 …

Go to article

The Role Of Oxidative Stress In α-Amanitin-Induced Hepatotoxicityin An Experimental Mouse Model, Zerri̇n Defne Dündar, Mehmet Ergi̇n, İbrahi̇m Kilinç, Tamer Çolak, Pembe Oltulu, Başar Cander Jan 2017

The Role Of Oxidative Stress In α-Amanitin-Induced Hepatotoxicityin An Experimental Mouse Model, Zerri̇n Defne Dündar, Mehmet Ergi̇n, İbrahi̇m Kilinç, Tamer Çolak, Pembe Oltulu, Başar Cander

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate oxidative stress markers of liver tissue in a mouse α-amanitin poisoning model with three different toxin levels. Materials and methods: The mice were randomly divided into Group 1 (control), Group 2 (0.2 mg/kg), Group 3 (0.6 mg/kg), and Group 4 (1.0 mg/kg). The toxin was injected intraperitoneally and 48 h of follow-up was performed before sacrifice. Results: Median superoxide dismutase activities of liver tissue in Groups 3 and 4 were significantly higher than in Group 1 (for both, P = 0.001). The catalase activity in Group 2 was significantly higher, but in Groups 3 …

Go to article

First Prev Next Last