Digital Commons Network^™

Perceptions Of Wellness Among Community Dwelling Older Adults, Sara Johnson, April Schmiesing

Occupational Therapy Capstones

Most older adults prefer to age in place where they are more likely to experience greater health benefits and cost savings as opposed to living in skilled care facilities. Literature supports the role of occupational therapy in community-based wellness programming that helps older adults age in place; however, there is a need to conduct needs assessments to inform wellness program topics and activities. This study explores health and wellness needs of older adults living in a low-income, senior housing complex in order to inform current health and wellness programming provided at this site.

Researchers used a non-experimental, cross-sectional survey study …

Road To Recovery: An Online Guide To Prepare Parents Of Children Who Have Sustained A Major Burn Injury For Successful Home And Community Transition, Michelle Jones, Chad Oppegaard

Occupational Therapy Capstones

Children are the most vulnerable population and represent the highest rate of nonfatal burns resulting in prolonged hospitalization, disfigurement, and disability. These injuries can be a severely stressful experience for children and their families. As a result, it is important for the patient and family members to not focus only on immediate treatment, but recognize the importance of long-term care following discharge in order to effectively reintegrate the child back into the home and community.

A literature review was conducted to investigate the key components of burn care throughout the duration of recovery. Research identified that many parents feel helpless, …

Assisting Clients With Psychosocial Adjustment After Sustainment Of A Traumatic Hand Injury: A Therapist's Guide, Rachel Kos, Jessica Nordmeyer

Occupational Therapy Capstones

Purpose: Adaptation to psychosocial aspects of hand injury is often undervalued, yet a critical issue to address in traumatic hand injuries (Schier & Chan, 2007). The purpose of this scholarly project was to develop a guide to address such factors in a hand therapy setting.

Methodology: A review of the literature was conducted to demonstrate the importance of hands, psychosocial implications related to hand trauma, and current strategies used by practitioners to address these problem. Findings of the literature review concluded that the most prevalent psychological factors related to hand injuries include mood and trauma disorder symptomatology, problems related to …

Occupational Therapy Resource Guide For The Utilization Of Three-Dimensional Printing, Andrew Ostrander, Jacy Whaley

Occupational Therapy Capstones

Many practitioners in the field of occupational therapy are unaware of the benefits and importance of implementing a three-dimensional (3D) printer in practice indicating that there is a need for occupational therapy involving the fitting, environmental modifications, and training on how to properly use a 3D printed prosthetic within the upper extremity. 3D printing is when a digital design is converted into a designed material that has a functional purpose and different materials can be used including metal, plastics, and composite materials (Thomas & Claypole, 2016). 3D printing has many unique and effective uses like creating adaptive devices, feeding devices, …

Addressing Sleep Deficiencies In Older Adult Residents Of Long-Term Care Facilities: Presenting A Flowchart For An Interdisciplinary Approach, Peter Owens, Tavin Deru

Occupational Therapy Capstones

There is a growing population of older adults, or those people over 65 years old in long term care (LTC) facilities who report sleep deficiencies at a heightened rate, leading to decrease function, cognition, and social participation while increasing mortality, morbidity and the risk of falling (Booth & McMilliam, 2009; Cipolli, Mazzetti, & Plazzi, 2013; Crowley, 2011; Dzierewski et al., 2014; Helbig et al., 2013; Kuck, Pantke, & Flick, 2015). Occupational therapists (OTs) offer non-pharmacological sleep interventions in the long-term care facilities but are not present at many relevant sleeping times. This scholarly project is a flow chart aid to …

Female Veterans And Homelessness: A Resource Guide For Occupational Therapists, Jamie Schacht, Alison Tonsager

Occupational Therapy Capstones

Female veterans are the fastest growing subpopulation among the homeless population in the United States (U.S.) (Boothe, 2017). Female veterans report lack of access to gender-specific programs and therapy groups within the United States Department of Veterans Affairs (VA) to meet specific needs post-deployment (U.S. Department of Veterans Affairs, 2015b). Difficulty with reintegration post-deployment has been linked with homelessness among female veterans. There is evidence to support female veterans' over-representation in the homeless population is due to a higher prevalence of risk factors for homelessness as compared to male veterans and females within the general population (Byrne, Montgomery, & Dichter, …

Postsecondary Transition Services For Students With Autism Spectrum Disorder: An Occupational Therapy Approach, Luke Van Havermaet, Lynn Bielski

Occupational Therapy Capstones

Problem: Individuals with Autism Spectrum Disorder comprise a rapidly growing population with approximately 1168 children being diagnosed annually (CDC, 2016). Individuals with ASD often have difficulties with social interaction, sensory processing, emotional regulation and adapting to environmental changes (Rogers, 2010). Individuals who are diagnosed early in life are provided a wide variety of services to minimize these symptoms to maximize independence later in life, and in an academic setting. As individuals with Autism Spectrum Disorder come to the end of their K-12 education journey, the transition planning completed throughout the student's final year of high school are not carried out …

Using Evidence To Address Psychosocial Impairments Post-Stroke: A Guide For Occupational Therapy, Michael Thurn, Emilee Rath

Occupational Therapy Capstones

Introduction: Following a stroke, individuals experience a wide variety of physical and psychosocial impairments. While physical impairments are commonly given attention by medical practitioners, psychosocial impairments are often overlooked or undiagnosed. (Hildebrand, 2015). Unfortunately, the same is true in occupational therapy, where physical and psychosocial issues have not been receiving the same amount of attention, physical issues being addressed far more than psychosocial issues (Gillen, 2014). The purpose of this scholarly project is to provide occupational therapists a guide to use of current evidence-based assessments and interventions to address psychosocial impairments following stroke. The guide focuses on evidence-based assessments, and …

A Health Care Provider Training Guide To Enhance Cultural Competency In Long-Term Care, Julia Mcbrien, Ashley Prososki

Occupational Therapy Capstones

The population of adults over the age of 65 in the United States is steadily increasing and becoming more diverse. Older adults are the greatest consumer of health care services, and they have unique health care needs. One notable health care need pertains to cultural beliefs and wants. When health care providers address the diverse needs of older adults, health outcomes improve for the client and communication across the interprofessional team improves. Therefore, the students of this scholarly project created a series of three, 50-minute long training sessions focused on training health care providers how to be culturally competent in …

Hla-Bw4-I-80 Isoform Differentially Influences Clinical Outcome As Compared To Hla-Bw4-T-80 And Hla-A-Bw4 Isoforms In Rituximab Or Dinutuximab-Based Cancer Immunotherapy, Amy Erbe, Wei Wang, Patrick Reville, Lakeesha Carmichael, Kyungmann Kim, Mehmet F. Ozkaynak, Paul Sondel

NYMC Faculty Publications

Killer-cell immunoglobulin-like receptors (KIRs) are a family of glycoproteins expressed primarily on natural killer cells that can regulate their function. Inhibitory KIRs recognize MHC class I molecules (KIR-ligands) as ligands. We have reported associations of KIRs and KIR-ligands for patients in two monoclonal antibody (mAb)-based trials: (1) A Children's Oncology Group (COG) trial for children with high-risk neuroblastoma randomized to immunotherapy treatment with dinutuximab (anti-GD2 mAb) + GM-CSF + IL-2 + isotretinion or to treatment with isotretinoin alone and (2) An Eastern Cooperative Oncology Group (ECOG) trial for adults with low-tumor burden follicular lymphoma responding to an induction course of …

Characteristics Of Hiv-Infected Children At Enrollment Into Care And At Antiretroviral Therapy Initiation In Central Africa, A Adedimeji, A Edmonds, Donald R. Hoover, Qiuhu Shi, J Sinayobye, M Nduwimana, P Lelo, D Nash, K Anastos, M Yotebieng

NYMC Faculty Publications

BACKGROUND: Despite the World Health Organization (WHO) regularly updating guidelines to recommend earlier initiation of antiretroviral therapy (ART) in children, timely enrollment into care and initiation of ART in sub-Saharan Africa in children lags behind that of adults. The impact of implementing increasingly less restrictive ART guidelines on ART initiation in Central Africa has not been described. MATERIALS AND METHODS: Data are from the Central Africa International Epidemiologic Databases to Evaluate AIDS (IeDEA) pediatric cohort of 3,426 children (0-15 years) entering HIV care at 15 sites in Burundi, DRC, and Rwanda. Measures include CD4 count, WHO clinical stage, age, and …

Pipeline Embolization Device As Primary Treatment For Cervical Internal Carotid Artery Pseudoaneurysms, Arthur Wang, Justin Santarelli, Michael Stiefel

NYMC Faculty Publications

BACKGROUND: Limited data exists on the durability and occlusion rate of treating extracranial cervical internal carotid artery pseudoaneurysms using the pipeline embolization device (PED) flow-diverting stent. METHODS: Three patients presenting with dissecting cervical internal carotid artery pseudoaneurysms were treated with the PED as the sole treatment modality. RESULTS: In all three patients, successful aneurysmal occlusion and parent vessel reconstruction occurred on immediate angiography and continued on 6-month follow-up. No immediate or delayed complications were seen, and all patients remained neurologically intact. CONCLUSION: Complete aneurysmal occlusion and long-term angiographic occlusion can occur after PED treatment of cervical carotid pseudoaneurysms. In select …

Anti-Proliferative Role Of Recombinant Lethal Toxin Of Bacillus Anthracis On Primary Mammary Ductal Carcinoma Cells Revealing Its Therapeutic Potential, Rekha Khandia, Bramhadev Pattnaik, Katherikamem Rajukumar, Atul Pateriya, Sandeep Bhatia, Harshad Murugkar, Anil Prakash, Hare Krishna Pradhan, Kildeep Dhama, Ashol Munjal, Sunil K. Joshi

Bioelectrics Publications

Bacillus anthracis secretes three secretary proteins; lethal factor (LF), protective antigen (PA) and edema factor (EF). The LF has ability to check proliferation of mammary tumors, chiefly depending on mitogen activated protein kinase (MAPK) signaling pathway. Evaluation of therapeutic potential of recombinant LF (rLF), recombinant PA (rPA) and lethal toxin (rLF + rPA = LeTx) on the primary mammary ductal carcinoma cells revealed significant (p < 0.01) reduction in proliferation of tumor cells with mean inhibition indices of 28.0 ±1.37% and 19.6 ± 1.47% respectively. However, treatment with rPA alone had no significant anti-proliferative effect as evident by low mean inhibition index of 3.4 ± 3.87%. The higher inhibition index observed for rLF alone as compared to LeTx is contrary to the existing knowledge on LF, which explains the requirement of PA dependent endocytosis for its enzymatic activity. Therefore, the plausible existence of PA independent mode of action of LF including direct receptor mediated endocytosis or modulation of signal transduction cascade via unknown means is hypothesized. In silico protein docking analysis of other cellular receptors for any plausibility to play the role of receptor for LF revealed c-Met receptor showing strongest affinity for LF (H bond = 19; Free energy = …

Pd-1, Pd-L1 (B7-H1) And Tumor-Site Immune Modulation Therapy: The Historical Perspective, J Wang, R Yuan, W Song, J Sun, Delong Liu, Z Li

NYMC Faculty Publications

The current success of targeted inhibition against cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and Programmed Death 1/Programmed Death Ligand 1 (PD-1/PD-L1, herein collectively referred to as PD) pathways is hailed as a cancer immunotherapy breakthrough. PD-L1, known also as B7 homolog 1 (B7-H1), was initially discovered by Dr. Lieping Chen in 1999. To recognize the seminal contributions by Chen to the development of PD-directed therapy against cancer, the Chinese American Hematologist and Oncologist Network (CAHON) decided to honor him with its inaugural Lifetime Achievement Award in Hematology and Oncology at the CAHON's 2015 annual meeting. This essay chronicles the important discoveries …

The Role Of Internalized Homonegativity In The Faith And Psychological Health Of Lesbians, Dane R. Whicker, Ed De St. Aubin, Kimberly R. Skerven

Psychology Faculty Research and Publications

Among lesbians, faith-based beliefs and behaviors may be associated with negative psychological health due to the interplay between religious and sexual identities. The present study examined health outcomes, faith-based beliefs (views of God as loving and controlling), faith-based behaviors (personal spiritual practices, religious activities), and internalized homonegativity in a sample of 225 self-identified lesbians. We hypothesized that internalized homonegativity would moderate the relationship between health outcomes and faith-based beliefs and behaviors among lesbians. Generally, results indicated that some faith-based beliefs and behaviors were related to negative health outcomes among lesbians with higher levels of internalized homonegativity, but among those with …

Adverse Consequences To Assisting Victims Of Campus Violence: Initial Investigations Among College Students, Alison Krauss, Ernest N. Jouriles, Kristen Yule, John H. Grych, Kelli S. Sargent, Victoria Banyard

Psychology Faculty Research and Publications

Despite growing interest in the use of bystander education programs to address the problems of sexual and relationship violence on college campuses, little knowledge exists on adverse consequences experienced by students intervening as a bystander. The current study examined the prevalence and correlates of adverse consequences of bystander intervention in two samples of first-year college students. In Study 1, 281 students completed a measure of negative consequences experienced when acting as a bystander to help someone at risk of sexual assault, relationship abuse, or stalking. Efficacy for bystander behavior was also assessed. Approximately one third of the students (97/281) reported …

Six Degrees Of Freedom: Kinematics Of The Healthy Ankle Syndesmosis Joint, Veronica A. Hogg-Cornejo

Electronic Theses and Dissertations

Syndesmotic injury, more commonly known as a "high ankle sprain", accounts for over 12% of all ankle sprain incidents in the US; of which, over 25% occur during a sporting activity. Typically, harm to the syndesmosis occurs in sports such as football, soccer, lacrosse, and hockey where it is common for an athlete to experience rapid and extreme dorsiflexion-external rotations of the foot. Severe syndesmotic sprains have been noted by clinicians as the most difficult ankle injury to accurately diagnose and treat, require the most recuperation time, and often results in life-long dysfunction. Even more problematic, 40% of patients suffering …

Improved Characterization And Analysis Strategies For Uv-Lif Bioaerosol Instrumentation: Lab And Field Application, Nicole Justine Savage

Electronic Theses and Dissertations

Atmospheric particles of biological origin, also referred to as bioaerosols or primary biological aerosol particles (PBAP), are important to various human health and environmental systems. There has been a recent steep increase in the frequency of published studies utilizing commercial instrumentation based on ultraviolet laser/light-induced fluorescence (UV-LIF), such as the WIBS (wideband integrated bioaerosol sensor), for bioaerosol detection both outdoors and in the built environment. Significant work over several decades supported the development of these technologies, but efforts to systematically characterize the operation of new commercial sensors has remained lacking. Specifically, there are gaps in the understanding of how different …

Estimating Swiss Chard Foliar Macro- And Micronutrient Concentrations Under Different Irrigation Water Sources Using Ground-Based Hyperspectral Data And Four Partial Least Squares (Pls)-Based (Pls1, Pls2, Spls1 And Spls2) Regression Algorithms, Elfatih M. Abdel-Rahman, Onisimo Mutanga, John Odindi, Elhadi Adam, Alfred Odindo, Riyad Ismail

All Peer-Reviewed Publications

Timely information on crop foliar nutrient content provides a measure of crop nutritional and vitality status. Growers and farm managers use such information for precision crop management such as an appropriate fertilizer application to correct for any crop nutrient deficiencies at identified hotspots. Foliar heavy nutrient content could also be a direct indicator of crops having been polluted from the surroundings, which may be a result of heavy metals absorbed from, among others, contaminated soils and waste water. In the present study, we explored the potential use of four partial least squares (PLS)-based regression algorithms for estimating foliar Swiss chard …

Databases And Medical Publications, Edgard Nehme

International Arab Journal of Dentistry

“Satisfaction lies in the effort, not in the attainment,
full effort is full victory.”
Mahatma Gand

Impact Of Push-Pull Technology On The Nutritional Status Of Farmers' Children In Western Kenya, Nicholas O. Ogot, J. O. Pittchar, C. A.O. Midega, Z. R. Khan

All Peer-Reviewed Publications

This study examined the impact of push-pull technology (PPT) on the nutritional status of children aged 1-12 years. Non-push-pull (NPPT) farmers were used as a control group to establish a comparative model for this study. It determined household production, consumption, and surpluses, comparing the PPT adopters to the nonadopters; found out the incomes and food expenditures from farm products; found out the household dietary diversity scores; and finally found the nutritional status of the two household groups. A six faceted household-level metrics was employed. A sample of 216 households that registered 326 children was derived. This study was conducted in …

Response To Climate Risks Among Smallholder Farmers In Malawi: A Multivariate Probit Assessment Of The Role Of Information, Household Demographics, And Farm Characteristics, Chalmers Mulwa, Paswel Marenya, Dil Bahadur Rahut, Menale Kassie

All Peer-Reviewed Publications

Why do many smallholder farmers fail to adopt what appear to be relatively simple agronomic or management practices which can help them cope with climate-induced stressors? Using household and plot level data collected in 2011, we implement a multivariate probit model to assess the determinants of farmer adaptation behavior to climatic risks and the relative contribution of information, credit and education on the probability of adopting specific practices in response to adverse changes in weather patterns. We find that plot characteristics, credit constraints and availability of climate-related information explain the adoption of several of these practices. In relative terms, we …

One More Time: Why We Do Research On The Ministry Of Evangelism, George G. Hunter

Great Commission Research Journal

George Hunter has spent a lifetime studying the ministry of evangelism. Following his teenage conversion, he discovered that the ministry that helps pre-Christian people become new Christians was the most understudied of the Church’s ministries. In this article, he reports on how he studied, from multiple perspectives, the Church’s most essential (but most academically neglected) ministry. Hunter gradually discovered at least a dozen assumptions about evangelism in Protestant folk-wisdom that are typically more counterproductive than productive. He interfaces with these assumptions to suggest alternative views that are more academically warranted and practically effective. He concludes by inviting a generation of …

Theological Empathy And John Wesley’S Missional Field Preaching, Lenny Luchetti

Great Commission Research Journal

John Wesley cited several external reasons for his submission to field-preaching. These external factors include the persuasive requests of George Whitefield, the effectiveness of open-air preaching, and the closed doors of the Anglican Church. These usual suspects have received much attention among Wesley scholars. However, a closer look at Wesley’s writings, especially his A Farther Appeal to Men of Reason and Religion, reveals that internal motivators were at least as much to blame as external ones for driving Wesley to the fields. What initiated and sustained Wesley’s field-preaching for fifty-one years, despite the many inconveniences and dangers associated with this …

Health Information Needs, Source Preferences And Engagement Behaviours Of Women With Metastatic Breast Cancer Across The Care Continuum: Protocol For A Scoping Review, Carol A. Tucker, Mp Martin, Ray B. Jones

School of Nursing and Midwifery

No abstract provided.

Debt Counselling For Depression In Primary Care: An Adaptive Randomised Controlled Pilot Trial (Decoder Study), Mark B. Gabbay, Adele Ring, Richard Byng, Pippa Anderson, Rod S. Taylor, Caryn Matthews, T Harris, Vashti Berry, Paula Byrne, Elliot Carter, Pam Clarke, Laura Cocking, Suzanne Edwards, Richard Emsley, Mauro Fornasiero, Lucy Frith, S Harris, Peter Huxley, Siw Jones, Peter Kinderman, Michael King, Liv Kosnes, Daniel Marshall, Dave Mercer, Carl May, Debbie Nolan, Ceri Phillips, Tim Rawcliffe, Alexandra V. Sardani, Elizabeth Shaw, Sam Thompson, Jane Vickery, Brian Wainman, Mark Warner

Peninsula Medical School

BackgroundDepression and debt are common in the UK. Debt Counselling for Depression in Primary Care: an adaptive randomised controlled pilot trial (DeCoDer) aimed to assess the clinical effectiveness and cost-effectiveness of the addition of a primary care debt counselling advice service to usual care for patients with depression and debt. However, the study was terminated early during the internal pilot trial phase because of recruitment delays. This report describes the rationale, methods and findings of the pilot study, and implications for future research.ObjectivesThe overarching aim of the internal pilot was to identify and resolve problems, thereby assessing the feasibility of …

Tracking The Amphibian Pathogens Batrachochytrium Dendrobatidis And Batrachochytrium Salamandrivorans Using A Highly Specific Monoclonal Antibody And Lateral-Flow Technology, Michael J. Dillon, Andrew E. Bowkett, Michael J. Bungard, Katie M. Beckman, Michelle F. O'Brien, Kieran Bates, Matthew C. Fisher, Jamie R. Stevens, Christopher R. Thornton

Peninsula Medical School

The fungus Batrachochytrium dendrobatidis (Bd) causes chytridiomycosis, a lethal epizootic disease of amphibians. Rapid identification of the pathogen and biosecurity is essential to prevent its spread, but current laboratory-based tests are time-consuming and require specialist equipment. Here, we describe the generation of an IgM monoclonal antibody (mAb), 5C4, specific to Bd as well as the related salamander and newt pathogen Batrachochytrium salamandrivorans (Bsal). The mAb, which binds to a glycoprotein antigen present on the surface of zoospores, sporangia and zoosporangia, was used to develop a lateral-flow assay (LFA) for rapid (15 min) detection of the pathogens. The LFA detects known …

Suppression Of Mapk11 Or Hipk3 Reduces Mutant Huntingtin Levels In Huntington's Disease Models, Meng Yu, Yuhua Fu, Yijiang Liang, Haikun Song, Y Yao, Peng Wu, Y Yao, Yuyin Pan, Xue Wen, Lixiang Ma, Saiyin Hexige, Yu Ding, Shouqing Luo, Boxun Lu

Peninsula Medical School

No abstract provided.

Measuring Treatment Satisfaction In Ms: Is The Treatment Satisfaction Questionnaire For Medication Fit For Purpose?, Patrick Vermersch, Jeremy Hobart, Catherine Dive-Pouletty, Sylvie Bozzi, Steven Hass, Patricia K. Coyle

Peninsula Medical School

Background: The Treatment Satisfaction Questionnaire for Medication (TSQM) was designed to assess patient treatment satisfaction in chronic diseases. Its performance has not been examined in multiple sclerosis (MS). The 14 items of the TSQM cover four domains: Effectiveness, Side Effects, Convenience, and Global Satisfaction. Objective: To evaluate performance of the TSQM in patients with relapsing MS, using data collected from the TENERE study (NCT00883337), in which 324 patients received oral teriflunomide or subcutaneous interferon beta-1a for ≥48 weeks. Methods: Five measurement properties were examined using traditional psychometric methods: data completeness, scale-to-sample targeting, scaling assumptions, reliability (including test-retest), and construct validity …

Droughts Of The Twentieth And Early Twenty First Centuries: Influences On The Production Of Beef And Forage In Kentucky, Usa, Rezaul Mahmood

School of Natural Resources: Faculty Publications

No abstract provided.