Digital Commons Network^™

Read-In Arts, An Liu

Theses and Dissertations

As interior designers, we strive to design everything for our clients, from complex environments to the joinery of a chair. We rarely consider inviting our clients or the users to join us in finishing the space.

Read-In workshop is not a school, but a kind of home, a home belonging to children, which provides the possibilities for children to play, to learn, to occupy, to personalize, and to share. An emotional space that will not limit the user, but keep inspiring them. It helps children notice, think, and grow.

Half of the interior space will be a fixed design, designed …

Comparison Of Intraoral And Extraoral Scanners On The Accuracy Of Digital Model Articulation, Jason L. Porter

Theses and Dissertations

Introduction: Orthodontists increasingly rely on digital models in clinical practice. The ability of modern scanners to articulate digital models must be scientifically evaluated. Methods:Twenty five digital articulated models were produced from four digital scanners in five experimental groups. The resulting inter-arch measurements were compared to the gold standard. An acceptable range of 0.5mm more or less than the gold standard was used for evaluation. Results: iTero® and iTero® Element yielded all acceptable inter-arch measurements. The 3M™ True Definition and Ortho Insight 3D® with Regisil® bite registration produced four of six acceptable inter-arch measurements. The Ortho Insight 3D® with Coprwax ™ …

A Multi-Method Exploration Of The Genetic And Environmental Risks Contributing To Tobacco Use Behaviors In Young Adulthood, Elizabeth K. Do

Theses and Dissertations

Tobacco use remains the leading preventable cause of morbidity and mortality in both the United States and worldwide. Twin and family studies have demonstrated that both genetic and environmental factors are important contributors to tobacco use behaviors. Understanding how genes, the environment, and their interactions is critical to the development of public health interventions that focus on the reduction of tobacco related morbidity and mortality. However, few studies have examined the transition from adolescent to young adulthood – the time when many individuals are experimenting with and developing patterns of tobacco use. This dissertation thesis seeks to provide a comprehensive …

Chemical Probes For Protein Α-N-Terminal Methylation, Brianna D. Mackie

Theses and Dissertations

While protein α-N-terminal methylation has been known for nearly four decades since it was first uncovered on bacteria ribosomal proteins L33, the function of this modification is still not entirely understood. Recent discoveries have demonstrated α-N-terminal methylation is essential to stabilize the interactions between regulator of chromosome condensation 1 (RCC1) and chromatin during mitosis, to localize and enhance the interaction of centromere proteins (CENPs) with chromatin, and to facilitate the recruitment of DNA damage-binding protein 2 (DDB2) to DNA damage foci. Identification of N-terminal methyltransferase 1 (NTMT1) unveiled the eukaryotic methylation writer for protein α-N-termini. In addition, NTMT2 that shares …

Development Of My Footprint Calculator, Karthik Mummidisetti

Theses and Dissertations

The Environmental footprint is a very powerful tool that helps an individual to understand how their everyday activities are impacting environmental surroundings. Data shows that global climate change, which is a growing concern for nations all over the world, is already affecting humankind, plants and animals through raising ocean levels, droughts & desertification and changing weather patterns. In addition to a wide range of policy measures implemented by national and state governments, it is necessary for individuals to understand the impact that their lifestyle may have on their personal environmental footprint, and thus over the global climate change. “My Footprint …

In Search Of A Function For An Uncharacterized Conserved Protein In Streptococcus Sanguinis Sk36, Ayana Scott-Elliston

Theses and Dissertations

With the number of fully sequenced bacterial genomes increasing in the past 7 years, it has been discovered that a large percentage of the putative protein coding genes have no known function. This lack of knowledge leaves scientists with an incomplete understanding of bacteria. In this study, conserved hypothetical protein mutants from Streptococcus sanguinis SK36 were screened on solid media with various environmental conditions. From these screens, the candidate protein, SSA_2372, displayed a sensitivity to acidic conditions. Its homolog in Bacillus subtilis 168, BSU00030, also displayed a sensitivity to pH conditions at its acid tolerance extremes unlike its other homolog …

Effects Of Prescribed Fire On Cope’S Gray Treefrog (Hyla Chrysoscelis) Across Habitat Scales And Life Stages, Logan Mcdonald

Theses and Dissertations

Fire may alter both aquatic and terrestrial habitat used by all amphibian life stages, yet, our knowledge of its effects on amphibians is primarily limited to adult responses. I present an integrated approach to test the response of Cope’s Gray Treefrog (Hyla chrysoscelis) to fire by examining responses in tadpole performance and survivorship, adult abundance, and oviposition. Tadpoles raised with burned leaf litter had similar survival, but total mass and total length were 440% and 170% greater, respectively, for tadpoles raised in unburned litter. I assessed terrestrial and aquatic oviposition cues by embedding burned and unburned litter treatments within burned …

The Third Place: A Mixed-Use Building For Office Workers In The Central Business District, Mingming Zhao

Theses and Dissertations

Work-related stress is an issue of growing concern around the world.[1] The relationship between work stress and individuals’ psychological and physical health is well acknowledged.[2] In the survey of “stress in the workplace” conducted by American Psychological Association in 2012, two in five (41%) of employed adults report that they typically feel stressed during the workday, up from 36% in 2011, while less than six in ten (58%) report that they have the resources to manage work stress.[3] Historically, Central Business Districts are a focal point of cities, and are occupied by a large group of office buildings and a …

Comparisons Of Isogenic Trisomic And Disomic Cells From People With Mosaicism For Down Syndrome Unmask Cellular Differences Related To Trisomy 21, Kelly A. Rafferty

Theses and Dissertations

It is known that age-related changes impacting multiple organ systems occur earlier in people with Down syndrome (Ds), but the biological basis underlying this trisomy 21-associated propensity for premature aging is poorly understood. Given that the trisomic/normal cells from people with mosaic Ds (mDs) are identical with regards to environmental exposures and genes (except for chromosome 21 copy number), comparisons of these isogenic trisomic/disomic cells allow one to “unmask” the cellular consequences of trisomy 21 by removing extraneous factors. The primary aim of this study was to determine if trisomy 21 results in an increase in the acquisition of age-related …

Reliability And Stability Of The Six Question Disability Measure In The Current Population Survey: What The Data Can And Cannot Tell Us About Disability And Labor Force Participation, Jeffrey Joy Dr.

Theses and Dissertations

The Current Population Survey (CPS) has been a major source of disability data for public policy and research. The aim of this study was two-fold. First, the study examined the six disability measures added to the CPS in 2008 to determine if they are both a reliable and stable method of describing disability over a period of two survey administrations in a 12-month period. Second, this study then assessed the impact of disability upon labor force participation. This research used a subset of the respondents to the longitudinal CPS Annual Social and Economic Supplement; it included (N=11,721) respondents …

2017 Msu Benefits Guide, Morehead State University. Office Of Human Resources.

Staff Congress Records

2017 Morehead State University Benefits Guide.

Regulation Of Hnrnpa1 By Micrornas Controls The Mir-18a–K-Ras Axis In Chemotherapy-Resistant Ovarian Cancer, Cristian Rodriguez-Aguayo, Paloma Del C Monroig, Roxana S Redis, Emine Bayraktar, Maria I Almeida, Cristina Ivan, Enrique Fuentes-Mattei, Mohammed H Rashed, Arturo Chavez-Reyes, Bulent Ozpolat, Rahul Mitra, Anil K Sood, George A Calin, Gabriel Lopez-Berestein

Faculty, Staff and Student Publications

The regulation of microRNA (miRNA) biogenesis, function and degradation involves a range of mechanisms, including interactions with RNA-binding proteins. The potential contribution of regulatory miRNAs to the expression of these RNA interactor proteins that could control other miRNAs expression is still unclear. Here we demonstrate a regulatory circuit involving oncogenic and tumor-suppressor miRNAs and an RNA-binding protein in a chemotherapy-resistant ovarian cancer model. We identified and characterized miR-15a-5p and miR-25-3p as negative regulators of hnRNPA1 expression, which is required for the processing of miR-18a-3p, an inhibitor of the

Strategic Planning For A Community Focused Non-Profit Organization, Erik W. Williams

Liberal Studies (MA) Final Essays

This paper explores the process used to create the Engage 2020 Strategic Plan for Family Service of Roanoke Valley, a 116 year non-profit in Roanoke, Va. Utilizing a community based process that focused on the strengths, opportunities, aspirations, and results; the strategic plan focused on improving the people and culture, programming and impact, and the vitality of the agency over a three-year period. Discussed in this paper are the history of the agency, its previous strategic plan, the planning, the process, and the end product strategic plan.

Flora Tristan’S Plural Identities In "Peregrinaciones De Una Paria": Challenging And Reproducing Existing Power Structures, Nancy Tille-Victorica

The Coastal Review

This article analyses the ways in which Franco-Peruvian author Flora Tristan crosses the border of her plural identities in her famous travel book Peregrinaciones de una paria (1837). It especially looks at how she performs as a male in certain situations and how these are generally associated with her French identity. It also considers her identification as a woman and how it is linked to her Peruvian identity. These examinations reveal how Tristan actually redefines herself as a pariah and how her definition differs from that of outcast imposed on her in France prior to her departure for Peru.

Vital Role Of Religion In The Calamitous World Of Today, Jovan Kovačić

Occasional Papers on Religion in Eastern Europe

No abstract provided.

Driving Courts Crazy: A Look At How Labor And Employment Laws Do Not Coincide With Ride Platforms In The Sharing Economy, Alyssa M. Stokes

Nebraska Law Review

I. Introduction

II. Background ... A. The “Sharing” Economy ... B. Who Is an Employee? ... 1. Misclassification of Employees as Independent Contractors ... 2. The Fair Labor Standards Act (FLSA) ... 3. California Wage and Hour Laws

III. Litigation for Ride Platforms in the Sharing Economy … A. Trouble for Uber Begins in Berwick v. Uber Technologies, Inc. ... 1. Facts ... 2. California Labor Commission Finds Uber Driver Is Employee ... B. California District Court Weighs in: O’Connor v. Uber Technologies, Inc. ... 1. Facts ... 2. The California District Court Weighs in on Uber’s Alleged Misclassification ... …

Deference And Fiction: Reforming Chevron’S Legal Fictions After King V. Burwell, Kurt Eggert

Nebraska Law Review

I. Introduction

II. The Tumultuous Passage of the Affordable Care Act

III. King v. Burwell and the Challenge to the ACA

IV. Chevron and “Step Zero” ... A. The Chevron Doctrine ... B. Chevron Step Zero

V. The Application of Chevron in King v. Burwell ... A. Chevron and the Lead-Up to King v. Burwell ... B. King v. Burwell and Chevron Step Zero ... C. King v. Burwell and Skidmore Deference

VI. How Chevron’s Fictions Lead to Chevron’s Confusion ... A. The Fictional Basis of Chevron ... B. Chevron’s Stare Decisis Muddle and the Need for …

Masthead & Table Of Contents, Vol. 95, No. 4

Nebraska Law Review

No abstract provided.

Indian Children And The Federal-Tribal Trust Relationship, Matthew L.M. Fletcher, Wenona T. Singel

Nebraska Law Review

I. Introduction

II. Indian Children and the Founding Generation ... A. The Treaty and International Law Basis of the Federal-Tribal Trust Relationship ... B. Federal Military and Diplomatic Actions ... 1. Colonial Era ... 2. Revolutionary War ... 3. Post-Revolutionary War Era ... 4. The Northwest Indian War ... 5. The Treaty of Greenville and the Founding Generation ... C. Federal Treaty and Statutory Law ... 1. Education and Schools ... 2. Land Rights ... 3. Other Provisions for Indian Orphans

III. Indian Children in the Coercive Period ... A. Interference in Internal Tribal Matters ... B. The Perversion of …

The Catch-22 Of Females Reporting Sexual Assault In The Military: A Cause For Holistic International Intervention, Kelsey E. B. Knoer

Nebraska Law Review

I. Introduction

II. Women in the Military ... A. General Background ... B. The Sexual Assault Problem: A Cross-Cultural Glance

III. The Underlying Issues: Hostile and Benevolent Sexism Across Cultures ... A. Ambivalent Sexism and Sexual Agency ... B. Gender Roles and Non-Conformance

IV. Applicable Law ... A. No Relief on the Home Front ... 1. The Uniform Code of Military Justice ... 2. Civilian Law ... 3. Testing the Boundaries of International Law

V. Suggestions for Reform: A Holistic Approach ... A. Setting an Example ... B. Going Deeper than the Law

VI. Conclusion

Indexes To Volume 95

Nebraska Law Review

No abstract provided.

Beyond The Network: A Holistic Perspective On State Cybersecurity Governance, Michael Garcia, David Forscey, Timothy Blute

Nebraska Law Review

I. Introduction

II. Governance: The New Frontier of Information Assurance

III. State Cybersecurity Governance Extends Beyond the Network

IV. Centralizing Security Governance to Defend State Networks

V. Governance Beyond Network Defense ... A. Disruption Response ... B. Law Enforcement ... C. Cybersecurity Centers

VI. Conclusion

Appendix: States and Indicators

The Modern Penny Dreadful: Public Prosecution And The Need For Litigation Privacy In A Digital Age, Jennifer A. Brobst

Nebraska Law Review

I. Introduction

II. Cybercrime and the Social Impact of Loss of Privacy

III. Balancing Constitutional Rights of Transparency with the Need for Anonymity in the Courtroom … A. Anonymous Juries ... B. Jane Doe Motions and Disclosure of Litigant and Witness Identities

IV. Limitations on the Right of Public Access to Court Proceedings ... A. Bans on Recording Devices in Court ... B. Closing the Courtroom

V. Public Records and Privacy-Related Exemptions

VI. Not So Private Rights of Action ... A. Statutory Remedies ... B. Defamation ... C. Invasion of Privacy ... D. Employee Harassment

VII. Conclusion

The Little Big Genome: The Organization Of Mitochondrial Dna, Iraselia Garcia, Edith Jones, Manuel Ramos, Wendy Innis-Whitehouse, Robert Gilkerson

School of Medicine Publications

The small (16,569 base pair) human mitochondrial genome plays a significant role in cell metabolism and homeostasis. Mitochondrial DNA (mtDNA) contributes to the generation of complexes which are essential to oxidative phosphorylation (OXPHOS). As such, mtDNA is directly integrated into mitochondrial biogenesis and signaling and regulates mitochondrial metabolism in concert with nuclear-encoded mitochondrial factors. Mitochondria are a highly dynamic, pleiomorphic network that undergoes fission and fusion events. Within this network, mtDNAs are packaged into structures called nucleoids which are actively distributed in discrete foci within the network. This sensitive organelle is frequently disrupted by insults such as oxidants and inflammatory …

A Grid-Based Approach To Localization For Robotics Applications, Larry Carlton Reaves

Graduate Theses, Dissertations, and Problem Reports (ETD)

From robotic probes on Mars to self driving cars here on Earth, the process of moving around the planet begins with localization. Before an autonomous vehicle can decide where to go, it must first determine where it is and what obstacles may be nearby. By using various sensors, an autonomous platform can gather the data it needs to identify its position and orientation within its surroundings. This position and orientation is known as the pose of the robot. In this report, we will review a particle filter based algorithm for localizing an autonomous mining robot in a known 2D map. …

Thrombectomy 6 To 24 Hours After Stroke With A Mismatch Between Deficit And Infarct, Raul G. Nogueira, Ashutosh P. Jadhav, Diogo C. Haussen, Alain Bonafe, Ronald J. Budzik, Parita Bhuva, Dileep R. Yavagal, Christophe Cognard, Ameer E. Hassan, Wondwossen G. Tekle

School of Medicine Publications

Background The effect of endovascular thrombectomy that is performed more than 6 hours after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is disproportionately severe relative to the infarct volume may benefit from late thrombectomy.

Methods We enrolled patients with occlusion of the intracranial internal carotid artery or proximal middle cerebral artery who had last been known to be well 6 to 24 hours earlier and who had a mismatch between the severity of the clinical deficit and the infarct volume, with mismatch criteria defined according to age (<80 years or ≥80 years). Patients were randomly assigned to thrombectomy plus standard care (the thrombectomy group) or to standard care alone (the control group). The coprimary end points were the mean score for disability on the utility-weighted modified Rankin scale (which ranges from 0 [death] to 10 [no symptoms or disability]) and the rate of functional independence (a score of 0, 1, or 2 on the modified Rankin scale, which ranges from 0 to 6, with higher scores indicating more severe disability) at 90 days.

Results A total of 206 patients …

Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment And Worse Outcome In The Stratis Registry (Systematic Evaluation Of Patients Treated With Neurothrombectomy Devices For Acute Ischemic Stroke), Michael T. Froehler, Jeffrey L. Saver, Osama O. Zaidat, Reza Jahan, Ameer E. Hassan

School of Medicine Publications

BACKGROUND: Endovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.

METHODS: STRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or …

Rehabilitation Of Deteriorated Timber Piles With Fiber Reinforced Composite Wrap Systems, John William Harper

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fiber reinforced polymer (FRP) composite wraps have been used for timber pile repair, but there is a lack of empirical data for the development of design guidelines and strengthening equations. To address this need, this study evaluated both the bond and compressive strength of four FRP wrap systems on whole timber piles. Wrap systems evaluated used glass fabric with epoxy, polyurethane, and phenol formaldehyde resins. Bond strengths were evaluated through push-out and pull-off bond testing data on new (unused) treated timber. The push-out test evaluated the bond strength of the wraps on timber by applying axial loads on wrapped (6" …

A Macroinvertebrate Bioassessment Of Two Streams On Turnbull National Wildlife Refuge (Tnwr), Sultan Mohammad Areshi

EWU Masters Thesis Collection

This project focused on highly impacted streams at Turnbull National Wildlife Refuge, Cheney, WA to evaluate the health status and ecosystem integrity of the water bodies. Turnbull National Wildlife Refuge contains over 3,000 acres of wetlands, and provides high quality habitat for migrating and breeding waterfowl. However, these wetlands are impacted by both high nutrient levels (Davidson and Rule 2006) and invasive fish (Scholz et al. 2003). This project focused on stream sections of the Company Ditch (CD) and Pine Draw (PD) watersheds. Company Ditch historically had very high nutrient levels and low water quality. Water quality may be improving …

Use Of Instructional Videos In Remediation To Enhance Dental Hygiene Students’ Restorative Skills, Cristina Lu

EWU Masters Thesis Collection

Purpose: Performing restorative procedures is one of the scopes of practice for dental hygienists in Washington State. To ensure dental hygiene students are clinically competent with their skills upon graduation, remediation is inevitable. However, with current challenges faculty face with traditional remedial interventions such as heavy workload and faculty availability, an alternative effective method of providing restorative remediation for dental hygiene students would be beneficial. This study investigated whether the use of instructional videos in remediation enhanced dental hygiene students’ restorative skills. Methods: This mixed-method study used a convenience sample of senior dental hygiene students. In this counterbalanced experimental design, …