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2017

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Frequency Sensitive Mechanism In Low-Intensity Ultrasound Enhanced Bioeffects, April D. Miller, Abdoulkadri Chama, Tobias M. Louw, Anuradha Subramanian, Hendrik J. Viljoen Aug 2017

Frequency Sensitive Mechanism In Low-Intensity Ultrasound Enhanced Bioeffects, April D. Miller, Abdoulkadri Chama, Tobias M. Louw, Anuradha Subramanian, Hendrik J. Viljoen

Department of Chemical and Biomolecular Engineering: Faculty Publications

This study presents two novel theoretical models to elucidate frequency sensitive nuclear mechanisms in low-intensity ultrasound enhanced bioeffects. In contrast to the typical 1.5 MHz pulsed ultrasound regime, our group previously experimentally confirmed that ultrasound stimulation of anchored chondrocytes at resonant frequency maximized gene expression of load inducible genes which are regulatory markers for cellular response to external stimuli. However, ERK phosphorylation displayed no frequency dependency, suggesting that the biochemical mechanisms involved in enhanced gene expression is downstream of ERK phosphorylation. To elucidate such underlying mechanisms, this study presents a theoretical model of an anchored cell, representing an in vitro …

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Quality And Yield Responses Of Seven Warm Season Forage Grasses To Partial Shading In A Simulated Silvopasture In East Texas, Jodi E. Hill Aug 2017

Quality And Yield Responses Of Seven Warm Season Forage Grasses To Partial Shading In A Simulated Silvopasture In East Texas, Jodi E. Hill

Electronic Theses and Dissertations

The goal of this project was to evaluate growth and nutritional characteristics of seven forages, including various warm season native grasses, grown under simulated partial shading (50%) typical of a loblolly pine silvopastoral system in East Texas. In order to meet the overall objective, slatted shade structures were constructed that simulated the quantity, quality, and overall light regime found beneath loblolly pine stands arranged for silvopasture. The forages selected for the study included ‘Tifton 9’ bahiagrass (Paspalum notatum), ‘Tifton 85’ bermudagrass (Cynodon dactylon), ‘Alamo’ switchgrass (Panicum virgatum), ‘Kaw’ Big Bluestem (Andropogon gerardii), ‘Americus’ …

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Interactive Physiological Responses Of Nile Tilapia To Salinity- And Temperature-Induced Stress: Quantifying The Coordination Of Apoptosis In Oreochromis Niloticus, Charlee Mcguire Aug 2017

Interactive Physiological Responses Of Nile Tilapia To Salinity- And Temperature-Induced Stress: Quantifying The Coordination Of Apoptosis In Oreochromis Niloticus, Charlee Mcguire

University Honors Theses

Nile tilapia provide an ideal model to study the accumulation of climate change-induced stressors due to their habitat in tropical freshwater systems that are susceptible to salt water invasion and temperature fluctuation due to sea level rise. This study investigates the physiological responses of Nile tilapia to salinity- and temperature-induced stress to identify the interactive effects of simultaneous stressors on the cell cycle. Proteins indicative of cell cycle activity and arrest were quantified in the tissues of Nile tilapia exposed to various environmental conditions varying by temperature and salinity. Dot Blotting was utilized to measure Gadd45 while Western Blotting was …

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Raps Sheet, Summer 2017, Retirement Association Of Portland State Aug 2017

Raps Sheet, Summer 2017, Retirement Association Of Portland State

RAPS Sheet: Monthly Newsletter

No abstract provided.

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Older Adults' Perceptions Of Nutrition As Protective Against Detrimental Effects Of Environmental Pollution, Kristina Dunn, Lisa Gaetke, Tammy Stephenson, Dawn Brewer Aug 2017

Older Adults' Perceptions Of Nutrition As Protective Against Detrimental Effects Of Environmental Pollution, Kristina Dunn, Lisa Gaetke, Tammy Stephenson, Dawn Brewer

Journal of Extension

The aging process makes older adults vulnerable to the detrimental health effects of environmental contaminants. Our study assessed older adults' perceptions regarding diet as protective against environmental contaminants, levels of concern about exposure to environmental contaminants, and interest in learning about protective food-related strategies. A needs assessment to collect such information had not been conducted among older adults. Health fair survey results showed that respondents perceived diet as beneficial against contaminants, were concerned about health implications of exposure, and were interested in learning how to protect health through diet-related strategies. Results suggest that a nutrition-focused curriculum addressing how dietary strategies …

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Evaluating The Effects Of "On-Task In A Box" As A Class-Wide Intervention For Increasing On-Task Behavior And Academic Performance, Allison Ashley Battaglia Aug 2017

Evaluating The Effects Of "On-Task In A Box" As A Class-Wide Intervention For Increasing On-Task Behavior And Academic Performance, Allison Ashley Battaglia

Dissertations

The present study was designed to replicate and extend the literature on the intervention package, On-Task in a Box, as a class-wide intervention to increase on-task behavior and decrease disruptive behavior. A second purpose of the study was to evaluate the effects of the intervention on students’ academic performance. The On-Task in a Box intervention utilized video modeling to train students on how to engage in on-task behavior, as well as how to self-monitor their behavior. Additionally, the intervention included students self-monitoring their on-task behavior using self-recording forms. Depending on select students’ percentage of on-task behavior on the self-recording forms, …

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The Effects Of Training Multiple Mands Within Functional Communication Training On The Resurgence Of Problem Behaviors, Emily Jane Ness Aug 2017

The Effects Of Training Multiple Mands Within Functional Communication Training On The Resurgence Of Problem Behaviors, Emily Jane Ness

Dissertations

Resurgence is the reoccurrence of a previously reinforced behavior when, under similar circumstances, a more recently reinforced behavior is placed on extinction (Epstein, 1985). The resurgence of problem behavior within the context of functional communication training (FCT) may occur when reinforcement is inadvertently thinned or placed on extinction due to low implementation integrity throughout the course of the intervention (Lieving et al., 2004). Techniques evaluated to mitigate resurgence of problem behavior have included long-term exposure to extinction (Wacker et al., 2011), signaled schedule thinning (Fuhrman, Fisher, and Greer, 2016), and a combination of both techniques (Wacker et al., 2013). These …

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An Ecological Examination Of Johnson Bayou (Pass Christian, Ms) With A Reproductive Histological Analysis Of Rangia Cuneata, And A Comparative Morphological Study Of The Foot And Shell Of Rangia Cuneata And Polymesoda Caroliniana, Brandon Drescher Aug 2017

An Ecological Examination Of Johnson Bayou (Pass Christian, Ms) With A Reproductive Histological Analysis Of Rangia Cuneata, And A Comparative Morphological Study Of The Foot And Shell Of Rangia Cuneata And Polymesoda Caroliniana, Brandon Drescher

Dissertations

Johnson Bayou is an estuarine system located in Pass Christian, MS. Research involved a biotic and abiotic examination of Johnson Bayou, resulting in the identification of numerous species of plants and animals, including Rangia cuneata (Mactridae) and Polymesoda caroliniana (Cyrenidae), sympatric species of infaunal bivalves. Environmental factors (e.g., water temperature, salinity) were measured over three years to describe the system from an abiotic standpoint, and used in a qualitative and quantitative reproductive histological study on R. cuneata. Results revealed differences in timing of gamete production and spawning between three subpopulations of this species. Sediment samples taken from the study …

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An Evaluation Of Behavioral Skills Training On The Implementation Of Peer-Mediated Discrete Trial Training, Christopher M. Furlow Aug 2017

An Evaluation Of Behavioral Skills Training On The Implementation Of Peer-Mediated Discrete Trial Training, Christopher M. Furlow

Dissertations

The purpose of this study was to evaluate the effects of behavioral skills training on the implementation of an evidence-based teaching method by student interventionists for children with autism spectrum disorder (ASD). Three elementary school students were trained to use an applied behavior analysis (ABA) based instructional method, known as discrete trial training (DTT), to teach academic skills to children with ASD. A multiple baseline across individuals was used to demonstrate the effectiveness of the behavioral skills training and peer-mediated DTT procedures. Generalization of the interventionist’s ability to teach new, previously untrained target behaviors was assessed by conducting generalization probes …

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Tootling With A Randomized Independent Group Contingency In A High School Setting, John Dylan Ken Lum Aug 2017

Tootling With A Randomized Independent Group Contingency In A High School Setting, John Dylan Ken Lum

Dissertations

Tootling is a procedure where students report their classmates’ positive and prosocial behavior. The present study examined the effects of tootling on students’ disruptive and academically engaged behavior in three general education high school classrooms. An A-B-A-B withdrawal design was used to assess the effects of the intervention. Students wrote tootles anonymously on paper slips and placed them into a marked container. Unlike previous tootling studies, a randomized independent group contingency procedure was used to reward the students to reduce the number of steps required to implement the intervention. At the end of the class period, teachers randomly drew three …

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The Saleing Subculture, Hayli M. Cox Aug 2017

The Saleing Subculture, Hayli M. Cox

All NMU Master's Theses

The Saleing Subculture is a collection of short and flash creative nonfiction essays with influences including travel writing, cultural studies, lyric essays, and memoir. Each essay attempts to contribute to a larger understanding of a unique subculture of yard salers as well as a single woman’s family dynamic within the culture. The collection also endeavors to interrogate relationships between people and the meanings they give to the objects they engage with or choose to cast away.

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The Effect Of Hyperthermic Whole Body Heat Stimulus (Sauna) On Heat Shock Protein 70 And Skeletal Muscle Hypertrophy In Young Males During Weight Training, Brandon C. Jones Mr. Aug 2017

The Effect Of Hyperthermic Whole Body Heat Stimulus (Sauna) On Heat Shock Protein 70 And Skeletal Muscle Hypertrophy In Young Males During Weight Training, Brandon C. Jones Mr.

All NMU Master's Theses

The traditional Finnish steam sauna is theorized to aid skeletal muscle hypertrophy by stimulating Heat Shock Protein 70 (HSP70), which acts as a molecular chaperone to the folding of functional skeletal muscle. The aim of this study was to investigate if stimulating HSP70 by using a sauna (45 – 50 ͦC, 80% Humidity) three times per week, for 15 minutes, could aid skeletal muscle hypertrophy during six weeks of resistance training in a young (21.38 ± 1.9 yrs.), recreationally trained male population. Thirteen subjects were randomly distributed into 3 groups [resistance Training + sauna (RT+S, n=5), RT + Relaxation (RT+R, …

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Post-Activation Potentiation: Decay Or Fatigue Delay, Ryan L. Meidinger Aug 2017

Post-Activation Potentiation: Decay Or Fatigue Delay, Ryan L. Meidinger

All NMU Master's Theses

Post-activation potentiation has been shown to improve jumping performance and other ballistic activities. The improvements in performance have been attributed to four main mechanisms, but the most important mechanism to the current study is the improvement in neural activity that leads to greater levels of potentiation. Post-activation potentiation has been shown to be stimulated by a maximal activity, called a conditioning contraction, and can be used as a warm up. In studies that have not shown the effects of post-activation potentiation, the proposed reason is fatigue, but the interaction of post-activation potentiation and fatigue have not been thoroughly tested. The …

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Comparison Of Aquaponics And Hydroponics On Basil (Ocimum Basilicum) Morphometrics And Essential Oil Composition, Lauren E. Wilson, Nathan C. Duncan, D. Andrew Crain Aug 2017

Comparison Of Aquaponics And Hydroponics On Basil (Ocimum Basilicum) Morphometrics And Essential Oil Composition, Lauren E. Wilson, Nathan C. Duncan, D. Andrew Crain

RURALS: Review of Undergraduate Research in Agricultural and Life Sciences

Soilless farming, though in practice for over two millennia, is becoming more prevalent in modern food production as it not only saves water and space but also provides an effective option for indoor urban farming. There are currently two major models of soilless farming—hydroponics and aquaponics. While both systems are effective methods, very few studies compare the two systems. The objective of this study was to compare the water quality, basil (Ocimum basilicum) productivity, and basil essential oil profiles from plants grown in a hydroponic and newly established aquaponic system. Basil plants from two age groups (young plants …

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Resolving Spatial And Temporal Variability In Dissolved Organic Matter Characteristics Within Combined Agricultural And Stormwater Conveyances, Bryce A. Mihalevich Aug 2017

Resolving Spatial And Temporal Variability In Dissolved Organic Matter Characteristics Within Combined Agricultural And Stormwater Conveyances, Bryce A. Mihalevich

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In many urban areas, stormwater runoff can threaten the ecological health of streams and downstream water bodies. Due to the increased impervious nature of urban landscapes, runoff is more “flashy” and as a result, high concentrations of pollutants can be transported in shorter periods of time than in more natural environments. One pollutant of concern is dissolved organic matter (DOM). DOM is important within aquatic ecosystems, but excess amounts can cause depletion in dissolved oxygen concentrations and can negatively affect aquatic organisms. This study investigated changes in DOM quantity and sources within the Northwest Field Canal (NWFC), an urban water …

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The Role Of Disease And Ectoparasites In The Ecology Of Nestling Golden Eagles, Benjamin Michael Dudek Aug 2017

The Role Of Disease And Ectoparasites In The Ecology Of Nestling Golden Eagles, Benjamin Michael Dudek

Boise State University Theses and Dissertations

Climate and anthropogenic land use changes can alter biological communities and affect disease infection rates and parasite species distribution and abundance. Management to mitigate the threats of emerging infectious diseases and parasite species requires identifying and understanding factors that influence individual susceptibility within populations. Golden eagles (Aquila chrysaetos) in southwestern Idaho face several current and emerging threats, including a landscape-mediated diet shift that has increased the potential for disease infection, and warming temperatures that may increase the distribution and abundance of hematophagous ectoparasites. We examined prevalence of Trichomonas gallinae infection in golden eagle nestlings across western North America …

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Landscape-Scale Manipulation Of The Acoustic Environment Alters The Distribution Of Breeding Birds And Arthropods, Elizeth Cinto-Mejia Aug 2017

Landscape-Scale Manipulation Of The Acoustic Environment Alters The Distribution Of Breeding Birds And Arthropods, Elizeth Cinto-Mejia

Boise State University Theses and Dissertations

Oil and gas development has rapidly increased across the world over the last several decades. Anthropogenic noise, an invisible pollutant that alters animal distribution and behavior, could be responsible for documented wildlife population declines near loud compressor stations in energy extraction fields. We experimentally played back compressor noise, creating a “phantom natural gas field” in a large-scale experiment, and tested the effects of noise on songbird distributions during the breeding season and on arthropod distributions. Further, to begin to understand the influence of noise produced by different types of extraction infrastructure, we examined the effects of sound intensity and bandwidth, …

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Space Use, Resource Selection, And Survival Of Reintroduced Bighorn Sheep, Rusty Wade Robinson Aug 2017

Space Use, Resource Selection, And Survival Of Reintroduced Bighorn Sheep, Rusty Wade Robinson

Theses and Dissertations

Successful management of bighorn sheep depends on understanding the mechanisms responsible for population growth or decline, habitat selection, and utilization distribution after translocations. We studied a declining population of desert bighorn sheep in the North San Rafael Swell, Utah to determine birthdates of neonates, demographics, limiting factors, population size, probable cause of death, production, and survival. We documented 19 mortalities attributed to a variety of causes including cougar predation (n = 10, 53%), bluetongue virus (n = 2, 11%), reproductive complications (n = 2, 11%), hunter harvest (n = 1, 5%), and unknown (n = 4, 21%). Annual survival of …

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The Relationship Between Expressed Creative Problem-Solving Preference And Divergent Thinking Attitudes, Jona A. Wright Aug 2017

The Relationship Between Expressed Creative Problem-Solving Preference And Divergent Thinking Attitudes, Jona A. Wright

Education Doctoral

The purpose of this study was to examine the relationship between an individual’s expressed creative problem style and divergent thinking attitudes. The problem-solving preferences were measured by the FourSight Breakthrough Thinking Profile and identified four preferences, Clarifier, Ideator, Developer, and Implementer. Divergent thinking attitudes, preference for ideation, and premature evaluation were measured by the 14 Item Ideation-Evaluation Preference Scale. The multidisciplinary sample was drawn from non-profit, business, education and higher education, specifically a Masters of Business Administration program. Significant relationships were found between the participants (N = 374) who identified with high Ideator and Implementer scores and preference for ideation. …

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Environmental Education In The Public Sphere: Comparing Practice With Psychosocial Determinants Of Behavior And Societal Change, Chris A. Bolt Aug 2017

Environmental Education In The Public Sphere: Comparing Practice With Psychosocial Determinants Of Behavior And Societal Change, Chris A. Bolt

Education Doctoral

Environmental education of the general public is widely practiced by a variety of types of organizations. Dedicated environmental groups, nature centers, zoos, parks, and other entities work on issues ranging from local threats to air, water, and habitat to global problems such as climate change and deforestation. A great deal of those efforts focus largely on providing information and raising awareness. Behavioral research and change models, however, suggest other factors are important in order to effect change on an individual, regional, or societal level. An analysis of environmental education in practice, examining methods and materials in use, showed the degree …

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Best Practices For Differentiated Learning Among Third Through Fifth Grade Ell Students, Tara J. Macias Aug 2017

Best Practices For Differentiated Learning Among Third Through Fifth Grade Ell Students, Tara J. Macias

Masters Theses

With the increase of second language English learners in U.S. kindergarten through twelfth grade schools and the continued achievement gap between these students and English speaking students, educators and administrators need to develop, implement and support best practices for differentiation among English Language Learners. ELL students are often categorized as special education students while their only barrier to learning is language acquisition. On the other hand, ELL students may have additional learning difficulties that are not identified because there is an assumption that language acquisition is the single challenge to their learning. Educators often engage in whole group instruction with …

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Hazardous Substance Emitters In Pakootas V. Teck Cominco Metals, Ltd. Are On Cloud Nine: Ninth Circuit Determines That Airborne Emissions Are Not Within The Purview Of Cercla Liability, Holly J. Sofield Aug 2017

Hazardous Substance Emitters In Pakootas V. Teck Cominco Metals, Ltd. Are On Cloud Nine: Ninth Circuit Determines That Airborne Emissions Are Not Within The Purview Of Cercla Liability, Holly J. Sofield

Villanova Environmental Law Journal (1991 - )

No abstract provided.

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Overflowing Generosity, Glenn Featherstone Douglass Aug 2017

Overflowing Generosity, Glenn Featherstone Douglass

ATS Dissertations

No abstract provided.

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Evaluating Relevance And Reliability Of Twitter Data For Risk Communication, Xiaohui Liu Aug 2017

Evaluating Relevance And Reliability Of Twitter Data For Risk Communication, Xiaohui Liu

Dissertations

While Twitter has been touted to provide up-to-date information about hazard events, the relevance and reliability of tweets is yet to be tested. This research examined the relevance and reliability of risk information extracted from Twitter during the 2013 Colorado floods using five different approaches. The first approach examined the relationship between tweet volume and precipitation amount. The second approach explored the relationship between geo-tagged tweets and degree of damage. In the third approach, the spatiotemporal distribution of tweets was compared with flood extent. In the fourth approach, risk information from tweets were compared with survey responses obtained in a …

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Queering The Future: Examining Queer Identity In Afrofuturism, Caleb Royal Mckinley-Portee Aug 2017

Queering The Future: Examining Queer Identity In Afrofuturism, Caleb Royal Mckinley-Portee

Theses

AN ABSTRACT OF THE THESIS OF CALEB MCKINLEY-PORTEE for the MASTER OF ARTS degree in COMMUNICATION STUDIES, presented on JULY 5TH, 2017 at Southern Illinois University Carbondale. TITLE: QUEERING THE FUTURE: EXAMINING QUEER IDENTITY IN AFROFUTURISM. MAJOR PROFESSOR: Dr. Craig Gingrich-Philbrook This thesis examines the art aesthetic known as Afrofuturism. The research provided examines Afrofuturism in music, art, and literature. This thesis provides an example of applying Afrofuturism to performance studies within Communication Studies. This thesis contains the script to a solo performance art piece which attempts to build a bridge between performance studies and Afrofuturism, while also examining Black, …

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Summer Habitat Use By A Mammal Community Of An Oak-Dominated Ecosystem In The Central Hardwood Region, Brent Steven Pease Aug 2017

Summer Habitat Use By A Mammal Community Of An Oak-Dominated Ecosystem In The Central Hardwood Region, Brent Steven Pease

Theses

In the greater Central Hardwood Region, advance regeneration of oak (Quercus spp.) and hickory (Carya spp.) has been in decline for several decades. Facilitated in part by an abrupt change in disturbance regime, coupled with an increase in herbivore density, the existing mid-successional, mast-producing species are being outcompeted by late-successional, mesophytic species. Oak-hickory forests provide keystone resources for a diverse forest wildlife community, and a decline in its dominance will likely impact habitat use and occupancy patterns in the mammal community, but to what extent is unclear. During May-August 2015-2016, I deployed 150 remotely-triggered camera traps in Trail of Tears …

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April:Taci Axis Is Dispensable For The Immune Response To Rabies Vaccination., Shannon L. Haley, Evgeni P. Tzvetkov, Andrew G. Lytle, Kishore R. Alugupalli, Joseph R. Plummer, James P. Mcgettigan Aug 2017

April:Taci Axis Is Dispensable For The Immune Response To Rabies Vaccination., Shannon L. Haley, Evgeni P. Tzvetkov, Andrew G. Lytle, Kishore R. Alugupalli, Joseph R. Plummer, James P. Mcgettigan

Department of Microbiology and Immunology Faculty Papers

There is significant need to develop a single-dose rabies vaccine to replace the current multi-dose rabies vaccine regimen and eliminate the requirement for rabies immune globulin in post-exposure settings. To accomplish this goal, rabies virus (RABV)-based vaccines must rapidly activate B cells to secrete antibodies which neutralize pathogenic RABV before it enters the CNS. Increased understanding of how B cells effectively respond to RABV-based vaccines may improve efforts to simplify post-exposure prophylaxis (PEP) regimens. Several studies have successfully employed the TNF family cytokine a proliferation-inducing ligand (APRIL) as a vaccine adjuvant. APRIL binds to the receptors TACI and B cell …

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Kansas Dairy Producers' Needs Survey: Reproductive Management On Kansas Dairy Farms, Benjamin E. Voelz, Caleigh E. Payne, Lindsey Hulbert, Jeffrey S. Stevenson, Michael Brouk, Luis G.D. Mendonça Aug 2017

Kansas Dairy Producers' Needs Survey: Reproductive Management On Kansas Dairy Farms, Benjamin E. Voelz, Caleigh E. Payne, Lindsey Hulbert, Jeffrey S. Stevenson, Michael Brouk, Luis G.D. Mendonça

Journal of Extension

A section of the Kansas Dairy Producers' Needs Survey evaluated needs related to education on reproductive management and the most common reproductive management practices used on Kansas dairy farms. Of the 312 surveys mailed to dairy producers, 70 were returned fully completed. Results indicate that producers need education on the topic of reproduction and that reproductive management practices and herd sizes are related to where farms are located in the state. Consequently, future Extension reproductive management programming should reflect the diversity of Kansas's dairy industry. Moreover, the results presented align with earlier data from a nationwide survey and therefore may …

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Food Safety Risks Of Leafy Greens From Small-Acreage Farms In Minnesota, Cindy Tong, Michele Schermann, Francisco Diez-Gonzalez, Jonathan Rossbach Aug 2017

Food Safety Risks Of Leafy Greens From Small-Acreage Farms In Minnesota, Cindy Tong, Michele Schermann, Francisco Diez-Gonzalez, Jonathan Rossbach

Journal of Extension

To focus future good agricultural practices (GAP) educational efforts, we surveyed leafy greens growers about their farming practices and measured microbial load on greens. Most survey respondents used potable water without added sanitizer for washing. Pathogenic bacterial levels were undetectable or low on farm and farmers' market samples. Coliform counts were in the normal range and were similar across farms and treatments. The microbial food safety risk from locally grown leafy greens appeared to be low. Therefore, future outreach efforts can focus on worker hygiene and cleanliness of farming operations, making GAP training less onerous for growers.

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Determination Of Coenzyme A And Acetyl-Coenzyme A In Biological Samples Using Hplc With Uv Detection, Yevgeniya Shurubor, M D'Aurelio, J Clark-Matott, E Isakova, Y Deryabina, M Beal, Arthur Cooper, Boris Krasnikov Aug 2017

Determination Of Coenzyme A And Acetyl-Coenzyme A In Biological Samples Using Hplc With Uv Detection, Yevgeniya Shurubor, M D'Aurelio, J Clark-Matott, E Isakova, Y Deryabina, M Beal, Arthur Cooper, Boris Krasnikov

NYMC Faculty Publications

Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) play essential roles in cell energy metabolism. Dysregulation of the biosynthesis and functioning of both compounds may contribute to various pathological conditions. We describe here a simple and sensitive HPLC-UV based method for simultaneous determination of CoA and acetyl-CoA in a variety of biological samples, including cells in culture, mouse cortex, and rat plasma, liver, kidney, and brain tissues. The limits of detection for CoA and acetyl-CoA are >10-fold lower than those obtained by previously described HPLC procedures, with coefficients of variation

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