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Serum D-Dimer Test Is Promising For The Diagnosis Of Periprosthetic Joint Infection And Timing Of Reimplantation., Alisina Shahi, Michael M. Kheir, Majd Tarabichi, Hamid R.S. Hosseinzadeh, Timothy L. Tan, Javad Parvizi

Rothman Institute Papers

BACKGROUND: Despite the availability of a battery of tests, the diagnosis of periprosthetic joint infection (PJI) continues to be challenging. Serum D-dimer assessment is a widely available test that detects fibrinolytic activities that occur during infection. We hypothesized that patients with PJI may have a high level of circulating D-dimer and that the presence of a high level of serum D-dimer may be a sign of persistent infection in patients awaiting reimplantation.

METHODS: This prospective study was initiated to enroll patients undergoing primary and revision arthroplasty. Our cohort consisted of 245 patients undergoing primary arthroplasty (n = 23), revision for …

The Biogenesis Pathway Of Trna-Derived Pirnas In Bombyx Germ Cells., Shozo Honda, Takuya Kawamura, Phillipe Loher, Keisuke Morichika, Isidore Rigoutsos, Yohei Kirino, Phd

Computational Medicine Center Faculty Papers

Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation. Molecular mechanisms that shape and regulate their expression profiles are largely unknown. Here, we report the mechanism of biogenesis for tRNA-derived Piwi-interacting RNAs (td-piRNAs) expressed in Bombyx BmN4 cells. In the cells, two cytoplasmic tRNA species, tRNAAspGUC and tRNAHisGUG, served as major sources for td-piRNAs, which were derived from the 5'-part of the respective tRNAs. cP-RNA-seq identified the two tRNAs as major substrates for the 5'-tRNA halves …

The Class Of 2021: By The Numbers, Jennifer Saunders

UNH Today Archive

No abstract provided.

Constitutionalism, Legitimacy, And Public Order: A South African Case Study, Aziz Huq

Public Law and Legal Theory Working Papers

No abstract provided.

Terrorism And Democratic Recession, Aziz Huq

Public Law and Legal Theory Working Papers

No abstract provided.

The People Against The Constitution, Aziz Huq

Public Law and Legal Theory Working Papers

No abstract provided.

The Triumph Of Fault In Public Law, Aziz Huq, Genevieve Lakier

Public Law and Legal Theory Working Papers

No abstract provided.

Key Role Of The Scavenger Receptor Marco In Mediating Adenovirus Infection And Subsequent Innate Responses Of Macrophages, Mareike D. Maler, Peter J. Nielsen, Nicole Stichling, Idan Cohen, Zsolt Ruzsics, Connor Wood, Peggy Engelhard, Maarit Suomalainen, Ildiko Gyory, Michael Huber, Joachim Müller-Quernheim, Wolfgang W.A. Schamel, Siamon Gordon, Thilo Jakob, Stefan F. Martin, Willi Jahnen-Dechent, Urs F. Greber, Marina A. Freudenberg, György Fejer

School of Biomedical Sciences

ABSTRACT The scavenger receptor MARCO is expressed in several subsets of naive tissue-resident macrophages and has been shown to participate in the recognition of various bacterial pathogens. However, the role of MARCO in antiviral defense is largely unexplored. Here, we investigated whether MARCO might be involved in the innate sensing of infection with adenovirus and recombinant adenoviral vectors by macrophages, which elicit vigorous immune responses in vivo. Using cells derived from mice, we show that adenovirus infection is significantly more efficient in MARCO-positive alveolar macrophages (AMs) and in AM-like primary macrophage lines (Max Planck Institute cells) than in MARCO-negative bone …

Comparing Tolerance Of Ambiguity In Veterinary And Medical Students, J Hancock, Ja Hammond, M Roberts, K Mattick

Peninsula Medical School

Current guidelines suggest that educators in both medical and veterinary professions should do more to ensure that students can tolerate ambiguity. Designing curricula to achieve this requires the ability to measure and understand differences in ambiguity tolerance among and within professional groups. Although scales have been developed to measure tolerance of ambiguity in both medical and veterinary professions, no comparative studies have been reported. We compared the tolerance of ambiguity of medical and veterinary students, hypothesizing that veterinary students would have higher tolerance of ambiguity, given the greater patient diversity and less well-established evidence base underpinning practice. We conducted a …

Revenue Ruling 78-248: The Congress And The Constitution Be Damned, Alfred L. Scanlan, Shea & Gardner, Washington, D.C.

The Catholic Lawyer

No abstract provided.

Religion, Sincerity, And Free Exercise, Peter J. Riga

The Catholic Lawyer

No abstract provided.

Photography And The Right To Privacy: The French And American Approaches, W. J. Wagner

The Catholic Lawyer

No abstract provided.

Plant-Expressed Cocaine Hydrolase Variants Of Butyrylcholinesterase Exhibit Altered Allosteric Effects Of Cholinesterase Activity And Increased Inhibitor Sensitivity, Katherine E. Larrimore, I. Can Kazan, Latha Kannan, R. Player Kendle, Tameem Jamal, Matthew Barcus, Ashini Bolia, Stephen Brimijoin, Chang-Guo Zhan, S. Banu Ozkan, Tsafrir S. Mor

Molecular Modeling and Biopharmaceutical Center Faculty Publications

Butyrylcholinesterase (BChE) is an enzyme with broad substrate and ligand specificities and may function as a generalized bioscavenger by binding and/or hydrolyzing various xenobiotic agents and toxicants, many of which target the central and peripheral nervous systems. Variants of BChE were rationally designed to increase the enzyme’s ability to hydrolyze the psychoactive enantiomer of cocaine. These variants were cloned, and then expressed using the magnICON transient expression system in plants and their enzymatic properties were investigated. In particular, we explored the effects that these site-directed mutations have over the enzyme kinetics with various substrates of BChE. We further compared the …

The Utah Statesman, September 5, 2017, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Current, September 05, 2017, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

Current, September 05, 2017, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

C. Elegans Avoids Toxin-Producing Streptomyces Using A Seven Transmembrane Domain Chemosensory Receptor, Alan Tran, Angelina Tang, Colleen O’Loughlin, Anthony Balistreri, Eric Chang, Doris Coto Villa, Joy Li, Aruna Varshney, Vanessa Jimenez, Jacqueline Pyle, Bryan Tsujimoto, Christopher Wellbrook, Christopher Vargas, Alex Duong, Nebat Ali, Sarah Matthews, Samantha Levinson, Sarah Woldemariam, Sami Khuri, Martina Bremer, Daryl Eggers, Noelle L’Etoile, Laura Miller Conrad, Miri Vanhoven

Faculty Publications, Chemistry

Predators and prey co-evolve, each maximizing their own fitness, but the effects of predator–prey interactions on cellular and molecular machinery are poorly understood. Here, we study this process using the predator Caenorhabditis elegans and the bacterial prey Streptomyces, which have evolved a powerful defense: the production of nematicides. We demonstrate that upon exposure to Streptomyces at their head or tail, nematodes display an escape response that is mediated by bacterially produced cues. Avoidance requires a predicted G-protein-coupled receptor, SRB-6, which is expressed in five types of amphid and phasmid chemosensory neurons. We establish that species of Streptomyces secrete dodecanoic acid, …

Columbia Chronicle (09/05/2017), Columbia College Chicago

Columbia Chronicle

Student newspaper from September 5, 2017 entitled The Columbia Chronicle. This issue is 48 pages and is listed as Volume 53, Issue 1. Cover story: "Convocation: celebrate no hate". Editor-in-Chief: Zoe Eitel

Ua12/2/1 College Heights Herald, Vol. 93, No. 5, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Coyle, Cameron & Emma Collins. WKU Student Fatally Shot on Sunday Morning – Kenneth Davis aka Alex
• Fletcher, Griffin. Remnants of Hurricane Harvey Hit WKU, Causes Flooding
• DeLetter, Emily. WKU, Bowling Green Assist with Hurricane Harvey Relief
• Eastham, Lillie. Walk 4 Water Fundraises for Clean Water
• Collins, Emma. Exercise Program Grows with Addition of Grants
• Leonard, Nicole. The Many Faces of Taylor Swift
• King, Jennifer. Editorial Cartoon re: Timothy Caboni’s Bowtie
• Reform the Norm: Importance of Support During Presidential Infancy – Timothy Caboni
• Peters, Patric. …

Student Movement - Issue 1, Andrews University

Student Movement v. 102 (2017-2018)

Issue 1

Enrichment Of Beneficial Bacteria In The Skin Microbiota Of Bats Persisting With White-Nose Syndrome, Virginie Lemieux-Labonté, Anouk Simard, Craig K. R. Willis

KIP Articles

Background Infectious diseases of wildlife are increasing worldwide with implications for conservation and human public health. The microbiota (i.e. microbial community living on or in a host) could influence wildlife disease resistance or tolerance. White-nose syndrome (WNS), caused by the fungus Pseudogymnoascus destructans (Pd), has killed millions of hibernating North American bats since 2007. We characterized the skin microbiota of naïve, pre-WNS little brown bats (Myotis lucifugus) from three WNS-negative hibernation sites and persisting, previously exposed bats from three WNS-positive sites to test the hypothesis that the skin microbiota of bats shifts following WNS invasion. Results Using high-throughput 16S rRNA …

Clean Water, Clean Life: Promoting Healthier, Accessible Water In Rural Appalachia, Erin Arcipowski, John Schwartz, Lisa Davenport, Meghan Hayes, Tracy Nolan

Journal of Contemporary Water Research and Education

In the rural Appalachian region of the United States, thousands of residents struggle with issues of water quality and accessibility. Vulnerabilities of poverty, isolation, and rough geographical terrain complicate life for Appalachians who need access to adequate water supply and septic systems. In 2013, an inter-professional team of nursing, architecture, engineering, and law enforcement faculty and students developed a water-focused collaboration with community members in southeastern Kentucky. Greater accessibility to clean drinking water is a critical need in the area. Collaborative community engagement yielded effective and sustainable interventions. Inter-professional teams completed N=30 comprehensive home assessments examining factors such as water …

Editorial: Language Development In The Digital Age, M Vulchanova, G Baggio, A Cangelosi, L Smith

School of Engineering, Computing and Mathematics

INTRODUCTION The digital age is changing our children’s lives and childhood dramatically. New technologies transform the way people interact with each other, the way stories are shared and distributed, and the way reality is presented and perceived. Parents experience that toddlers can handle tablets and apps with a level of sophistication the children’s grandparents can only envy. In Great Britain, a recent survey of preschoolers shows that a rising number of toddlers are now put to bed with a tablet instead of a bedtime story. In the USA, a telephone survey of 1,009 parents of children aged 2–24 months (Zimmerman …

Survey Of Rainwater Catchment Use And Practices On Hawaii Island, Mary J. Donohue, Patricia S.H. Macomber, Darren Okimoto, Darren T. Lerner

Journal of Contemporary Water Research and Education

The harvesting of rainwater for domestic use on Hawaii Island is widespread, particularly in areas not served by municipal water. Rainwater catchment is currently unregulated in Hawaii with the responsibility of installing and maintaining appropriate systems on owners and users. Well-designed and maintained rainwater catchment systems are more likely to provide water free of pathogens than poorly designed or maintained systems. We conducted outreach to rural Hawaii Island communities on rainwater catchment best practices and explored household uses and practices associated with these systems via survey of 110 individuals. Nearly 90% (N=96) of all survey respondents used harvested rainwater as …

Land Use Modification And Changing Redox Conditions Releases Selenium And Sulfur From Historic Marsh Sediments, Barry J. Hibbs, Monica Lee, Rachel Ridgway

Journal of Contemporary Water Research and Education

San Diego Creek Watershed forms the southern end of the Coastal Plain that covers much of Los Angeles County and Orange County, California. Prior to 1900, the central part of the watershed was marshland, and the edges of the watershed were used for grazing sheep and cattle. After 1900, cattle and sheep grazing were displaced by irrigated agriculture. Drainage ditches and channels were constructed to drain the marshes to “reclaim” the land for agriculture. Today, the drainage ditches and channels still exist in the watershed, which has undergone massive urban growth. Shallow groundwater discharges into these channels and ditches, which …

Interest Exceeds Understanding In Public Support Of Bee Conservation, Joseph S. Wilson, Matthew L. Forister, Olivia Messinger Carril

Biology Faculty Publications

Recent analyses suggesting that certain populations of bees may be declining have led to a variety of conservation efforts, many of which rely on public support and participation. However, little is known about the public's knowledge of bee diversity. We carried out a survey to measure public understanding of bee diversity and found that although 99% of respondents believed that bees are critical or important, only 14% were able to guess within 1000 the actual number of bee species in the US. Furthermore, when reviewing a selection of photographs depicting various insects, many respondents were unable to discern bees from …

Graves, Gifts, And The Bereaved Consumer: A Restorative Perspective Of Gift Exchange, Jenna M. Drenten, Kristy Mcmanus, Lauren I. Labrecque

School of Business: Faculty Publications and Other Works

When a gifting relationship is disrupted by death, why might a living consumer continue to invest in it? Consumer spending on deceased loved ones does not end with the funeral. Given the embodying power of a physical gravesite, this article examines the practice of gift giving to the deceased in the context of American cemeteries. We employ a longitudinal approach, in which 180 cemetery gravesites were photographed. The photographic data are coupled with a netnography of grief and bereavement communities. Findings support a restorative perspective of gift exchange. Bereaved consumers utilize restorative giving as a mechanism to cope with loss …

The George-Anne, Georgia Southern University

The George-Anne

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Rattlesnake Nuisance Removals And Urban Expansion In Phoenix, Arizona, Steven L. Pitts, Bryan D. Hughes, Ivana Mali

Western North American Naturalist

Urbanization can have significant consequences on local wildlife. While some species can thrive in urban environments, others are often seen as nuisance animals and therefore are either killed by landowners or removed by professionals. Snakes, especially rattlesnakes, represent one such taxon. Here, we analyzed rattlesnake removal data from the city of Phoenix, Arizona, USA, to determine whether the removal data directly correlates with urban expansion. Between 2011 and 2014, over 500 rattlesnakes and over 300 non-rattlesnakes were removed by professionals, with significant removal clusters in the northern Phoenix metropolis. Land cover change analyses showed that all removal sites experienced dramatic …

Deconstructing The Monstrous She-Male: Castration And The Invisible Genital In The Liminal Personae, Jeremy Miller

Articulāte

No abstract provided.