Digital Commons Network^™

Nlrp10 Enhances Cd4+ T-Cell-Mediated Ifnγ Response Via Regulation Of Dendritic Cell-Derived Il-12 Release, Maurizio Vacca, Julia Böhme, Lisa Zambetti, Hanif Javanmard Khameneh, Bhairav S. Paleja, Federica Laudisi, Adrian W. S. Ho, Kurt Neo, Keith Weng Kit Leong, Mardiana Marzuki, Bernett Lee, Michael Poidinger, Laura Santambrogio, Liana Tsenova, Francesca Zolezzi, Gennaro De Libero, Amit Singhal, Alessandra Mortellaro

Publications and Research

NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products. Here, we generated a Nlrp10−/− mouse to delineate the role of NLRP10 in the host immune response and found that Nlrp10−/− dendritic cells (DCs) elicited sub-optimal IFNγ production by antigenspecific CD4+ T cells compared to wild-type (WT) DCs. In response to T-cell encounter, CD40 ligation or Toll-like receptor 9 stimulation, Nlrp10−/− DCs produced low levels of IL-12, due to a substantial decrease in NF-κB activation. Defective IL-12 production was also evident in vivo and affected IFNγ production by CD4+ T cells. Upon …

The Next Step In Civil Asset Forfeiture Reform: Passing The Civil Asset Forfeiture Reform Act Of 2014, Daniel Reed

Catholic University Law Review

Civil asset forfeiture is an operation of legal fiction that enables the government to seize property without an underlying conviction of the property owner. Federal authorities bring thousands of civil asset forfeiture cases annually, often against the property of owners who have not been charged with a crime. Such cases can result in unjust outcomes and denials of due process to property owners. To address this controversy, Representative Tim Walberg proposed several reforms to federal civil asset forfeiture laws known as the Civil Asset Forfeiture Reform Act of 2014 (CAFRA 2014).

After discussing the history of civil asset forfeiture, this …

B Cell-Derived Il-4 Acts On Podocytes To Induce Proteinuria And Foot Process Effacement, Alfred Hj Kim, Jun-Jae Chung, Shreeram Akilesh, Ania Koziell, Sanjay Jain, Jeffrey B. Hodgin, Mark J. Miller, Thaddeus S. Stappenbeck, Jeffrey H. Miner, Andrey S. Shaw

Open Access Publications

The efficacy of B cell depletion therapies in diseases such as nephrotic syndrome and rheumatoid arthritis suggests a broader role in B cells in human disease than previously recognized. In some of these diseases, such as the minimal change disease subtype of nephrotic syndrome, pathogenic antibodies and immune complexes are not involved. We hypothesized that B cells, activated in the kidney, might produce cytokines capable of directly inducing cell injury and proteinuria. To directly test our hypothesis, we targeted a model antigen to the kidney glomerulus and showed that transfer of antigen-specific B cells could induce glomerular injury and proteinuria. …

Kenyon Collegian - November 2, 2017

The Kenyon Collegian

No abstract provided.

November 2, 2017, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Respecting Young People’S Informal Learning: Circumventing Strategic Policy Evasions, Jocey Quinn

Plymouth Institute of Education

No abstract provided.

Student Movement - Issue 8, Andrews University

Student Movement v. 102 (2017-2018)

Student Movement, Issue 8, 2017

The George-Anne, Georgia Southern University

The George-Anne

• 2017-18 Tipoff
• Campus Life
• Opinions
• Features
• News
• Sports
• Puzzles

Impacts Of Hunting And Life-History Stage On The Stress Physiology And Body Condition Of Fall And Wintering Mallards (Anas Platyrhynchos), Jerad Richard Henson

Electronic Theses and Dissertations Archive

Waterfowl face a multitude of stressors across the fall and winter. These stressors include energetic demands associated with annual cycle stage, weather, habitat availability, and waterfowl hunting seasons. Stressful stimuli elicit a physiologic stress response culminating with the release of corticosterone (CORT). CORT aids in survival and recovery over the short-term, but if elevated over a long period it can lead to decrements in health. To avoid the potential harmful effects of prolonged elevations in CORT, some birds seasonally dampen their response to a predictable stressor. The aim of this study was to examine the changes in stress physiology and …

Catholic Tradition, And The New Catholic Theology And Social Teaching On The Environment, Robert W. Lannan

The Catholic Lawyer

No abstract provided.

The Regulation Of Indecent Material Accessible To Children On The Internet, Joel Sanders

The Catholic Lawyer

No abstract provided.

Reveille (Issue 38), Csusb Veterans Success Center

Reveille newsletter

Look What's Inside...

• Military Not-So-Secret Code
• Norton AFB "An Evening at the Museum"
• Vet Hunter: Deletta Anderson
• Student Interviews
• DAV Garden
• Coast Guard Birthday

Men's Basketball Media Guide 2017-18, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Men's Tennis Media Guide 2017-18, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Women's Tennis Media Guide 2017-18, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Women's Basketball Media Guide 2017-18, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

2017 November 1 -- Agenda And Attachments

Agendas and Minutes

No abstract provided.

The Collegian: November 01, 2017, The Collegian Staff, South Dakota State University

The Collegian, 2017-2018

Volume 133

Issue 9

Volume 113 Issue 9, Southwestern Oklahoma State University

The Southwestern - Archive

No abstract provided.

Today - November 2017, Loma Linda University Health

TODAY

Inside this issue:

-- Loma Linda University Cancer Center receives 2017 ACCC Innovator Award

-- Modern Healthcare recognizes Angela Lalas as 2017 Up and Comer

-- Liver transplant program director Dr. Michael Volk named “2017 Healthcare Visionary”

-- Business incubator lands second research grant

-- Pathologists’ Assistant Program receives excellent accreditation summation

-- Martha Green’s surprising announcement during fundraiser for Children’s Hospital

-- Seeds of Hope event focuses on erasing stigma of mental illness, Recording Artist Michelle Williams visits Loma Linda University Health, shares her advocacy for mental health causes

-- Study finds new benefit for consuming nuts, Including nuts …

Featured Bookshelf: 2017 Native American Heritage Month, Megan M. Haught

Featured Bookshelf

November in the United States is Native American Heritage Month, also referred to as American Indian and Alaska Native Heritage Month. It celebrates the rich history and diversity of America’s native peoples and educates the public about historical and current challenges they face. Native American Heritage Month was first declared by presidential proclamation in 1990 which urged the United States to learn more about their first nations.

Join the UCF Libraries as we celebrate our favorite Native American authors and books. Click the keep reading link to see the full descriptions of the books.

Gingival Perfusion And Tissue Biomarkers During Early Healing Of Postextraction Regenerative Procedures: A Prospective Case Series, Lamees Alssum, Timothy D. Eubank, Sashwati Roy, Barbaros S. Erdal, Vedat O. Yildiz, Dimitris N. Tatakis, Binnaz Leblebicioglu

Clinical and Translational Science Institute

Background—Post-extraction alveolar bone loss, mostly affecting the buccal plate, occurs despite regenerative procedures. To better understand possible determinants, this prospective case series assessed gingival blood perfusion and tissue molecular responses in relation to postextraction regenerative outcomes. Methods—Adults scheduled to receive bone grafting in maxillary, non-molar, single tooth extraction site were recruited. Clinical documentation included probing pocket depth (PD), keratinized tissue width (KT), tissue biotype (TB), plaque (P) and bleeding. Wound closure was clinically evaluated. Gingival blood perfusion was measured by Laser Doppler Flowmetry (LDF). Wound fluid (WF) and gingival biopsies were analyzed for protein levels and gene expression, respectively, of …

Article 29: Joel At A Glance, Harold Willmington

The Owner's Manual File

No abstract provided.

Article 66: Revelation At A Glance, Harold Willmington

The Owner's Manual File

No abstract provided.

'A Prey To Their Teeth': Puritan Sermons And Ministerial Writings On Indians During King Philip's War, Gregory Michna

Faculty Publications - History & Political Science

King Philip’s War encouraged the construction of barbaric Native American typologies by puritan ministers through sermons and wartime histories. While select Algonquians in New England invested in a hybridized identity as a “Praying Indian” during the decades before the war, martial circumstances encouraged ministers to emphasize indigenous savagery, which outweighed earlier efforts to demonstrate the Christian piety of native converts. English texts outlining God’s providential wrath linked the contemporaneous war to Old Testament punishments meted out to the Hebrews. This typological reading of current events also superimposed the characteristics of heathen barbarians on Native Americans irrespective of their allegiance, offering …

In Vivo Bioluminescence Imaging Of Nuclear Factor Kappab Activation: A Valuable Model For Studying Inflammatory And Oxidative Stress In Live Mice, Hong Zhu, Zhenquan Jia, Michael A. Trush, Y R. Li

Osteopathic Medicine, Jerry M. Wallace School of

The nuclear factor kappaB (NF-κB) is a redox-sensitive transcription factor that plays a critical role in inflammation among other biological functions. This ROS Protocol article describes an in vivo bioluminescence imaging assay for assessing NF-κB activation using the commercially available transgenic mice carrying NF-κB response element-luciferase reporter gene (NF-κB-RE-Luc). Using the highly sensitive Berthold NightOwl LB981 in vivo bioluminescence imaging system, we are able to visualize the NF-κB activation in live mice under basal conditions, suggesting constitutive activation of NF-κB as a part of its fundamental biology. Treatment of mice with lipopolysaccharides (LPS) results in a drastic increase in bioluminescence, …

Educational Leadership Program November 2017, Educational Leadership Department, University Of Southern Maine

Educational Leadership Newsletters

Inside this issue:

• Musings from the Chair
• Southern Maine Partnership Update
• Thinking About Internship in 2018-2019?
• Spring 2018 Schedule

Faculty Senate Meeting Minutes – November 2017, Faculty Senators

Minutes 2017-2018

This is the archived record of the November 15, 2017 faculty senate meeting minutes.

Stones And Bones: Catholic Responses To The 1812 Collapse Of The Mission Church Of Capistrano, Karin Vélez

Faculty Publications

This essay delves into the 1812 collapse of the Great Stone Church at California’s Mission of San Juan Capistrano and its aftermath to consider how early modern Catholics in the greater Iberian world approached the material remains of ruined churches that contained human victims. Questions explored include how Franciscan missionaries reported and reacted to the calamity, why the casualties were disproportionately Indian and female, and what survivors did with the physical remnants of broken churches. Churches that collapsed on worshippers in Arequipa, Cuzco, Lima and Lisbon prior to 1812 are mustered for comparison. Overall, a pattern emerges of Catholics separating …

Spartan Daily, November 1, 2017, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2017

Volume 149, Issue 30