Digital Commons Network^™

Regulating Black-Box Medicine, W. Nicholson Price Ii

Michigan Law Review

Data drive modern medicine. And our tools to analyze those data are growing ever more powerful. As health data are collected in greater and greater amounts, sophisticated algorithms based on those data can drive medical innovation, improve the process of care, and increase efficiency. Those algorithms, however, vary widely in quality. Some are accurate and powerful, while others may be riddled with errors or based on faulty science. When an opaque algorithm recommends an insulin dose to a diabetic patient, how do we know that dose is correct? Patients, providers, and insurers face substantial difficulties in identifying high-quality algorithms; they …

Opening The Gates Of Cow Palace: Regulating Runoff Manure As A Hazardous Waste Under Rcra, Reed J. Mccalib

Michigan Law Review

In 2015, a federal court held for the first time that the Environmental Protection Agency (“EPA”) may regulate runoff manure as a “solid waste” under the Resource Conservation and Recovery Act (“RCRA”). The holding of Community Ass’n for Restoration of the Environment, Inc. v. Cow Palace, LLC opened the gates to regulation of farms under the nation’s primary toxic waste statute. This Comment argues that, once classified as a “solid waste,” runoff manure fits RCRA’s definition of “hazardous waste” as well. This reclassification would expand EPA’s authority to monitor and respond to the nation’s tragically common groundwater-contamination emergencies.

Role Of Cannabinoid Receptor Type 2 (Cb2) In Late Stage Atherosclerosis, Makenzie Fulmer

Electronic Theses and Dissertations

Atherosclerosis is a chronic inflammatory disorder of medium and large vessels. Immune signaling and dyslipidemia are two of several processes which influence lesion development in atherosclerosis. Cannabinoids, such as those found in marijuana, exert their effects through two cannabinoid receptors, CB1 and CB2. Recent studies using CB2 knockout mice and CB2-selective ligands have shed light on a protective role of CB2 in early stages of atherosclerosis. However, the role of CB2 in advanced stages of atherosclerosis remains unclear. To determine if CB2 plays a role in advanced atherosclerotic lesion composition and progression, we investigated the effects of systemic CB2 gene …

A Scarlet Ending, Alison J. Gibson

Undergraduate Honors Theses

Dancing a duet with my shadow by integrating dance and digital media in an elaborate and entertaining performance.

The Road To Autonomy, Michelle Sellwood

San Diego Law Review

[T]his Comment discusses the background of AI and robotics, the technology behind the autonomous vehicle, and the evolution of products liability laws. Part III examines current regulations, the benefits of autonomous technology, and the need for a definitive liability framework. Part IV discusses why current tort liability laws will be ineffective in governing autonomous vehicle liability by examining the shift in liability from the driver to the owner and manufacturer. Part V proposes a short-term solution by attributing liability to the programmer, while software is still hard-coded. Finally, Part VI explores legal personhood, and proposes that the autonomous vehicle be …

A Potential Solution To A Poopy Problem: Bile Salt Analogs As Prophylactics Against Clostridium Difficile Infection, Jacqueline Renee Phan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Clostridium difficile infection (CDI) is a major cause of antibiotic-associated diarrhea. In 2011, over 500,000 patients were diagnosed with CDI in the United States and over 29,000 people died of CDI-related complications. With an average of $35,000 to treat a single case of inpatient CDI, cost burden to the healthcare system can reach up to $3.2 billion annually. As both hospital- and community-acquired CDI incidences rise due to the emergence of hypervirulent strains and CDI reoccurrences of up to 25%, standard treatments are rendered less effective and new methods of prevention are critical.

CDI is caused by bacteria called Clostridium …

Influences Of Anthropogenic Noise On Flight Initiation Distance, Foraging Behavior, And Feeder Community Structure Of Wild Birds, Alissa R. Petrelli

Master's Theses

Throughout the world, birds represent the primary type of wildlife that people experience on a daily basis. However, a growing body of evidence suggests that alterations to the acoustic environment can negatively affect birds as well as humans in a variety of ways, and altered acoustics from noise pollution has the potential to influence human interactions with wild birds. In this thesis, I investigated how anthropogenic noise impacts daily behavior as well as community structure of wild birds. In the first component of this thesis, I assessed the distance at which a bird initiates flight or escape behavior (i.e., flight …

Improving Companion Ai Behavior In Mimica, Daniel Toy

Master's Theses

Companion characters are an important aspect of video games and appear in many different genres. Their role is typically to support the player as they progress through the game by helping to complete tasks or assisting in combat. However, oftentimes, these companion characters are limited in their ability to dynamically react to new situations and fail to properly assist the player.

In this paper, we present a solution by improving upon the MimicA framework, which allows companion characters to emulate the human player. The framework takes a learn by observation approach by storing the game state when the player performs …

Meeting The Distance Education Challenge: A Guide For Designing Online Classrooms, Patrick Allen Bungard

Electronic Theses, Projects, and Dissertations

The emphasis on education fluctuates with the economy. When education is encouraged, many individuals flock to colleges and universities to increase earning potential or achieve goals. Thanks to advancements in technology, distance education in the 21^st century can be similar to face-to-face education. Students spend many hours sitting in front of a computer completing course work. Although still in infancy stages, online education has vastly improved. Perspectives like teaching adults (andragogy), transformative learning, and teacher immediacy all address teaching individuals from afar. In consultation with these three perspectives, several qualitative measures have been developed aid with online course design. …

Effects Of Nicotine Exposure On Methamphetamine Oral Self-Administration, Extinction, And Reinstatement In Adolescent Rats, Zachary Robert Harmony

Electronic Theses, Projects, and Dissertations

Adolescence is a vulnerable developmental period in regards to drug initiation and use. The gateway hypothesis suggests that adolescent cigarette smoking may result in a heightened risk for methamphetamine use. However, little is understood about the role of nicotine on adolescent methamphetamine addiction. The aim of the present study was to determine whether early, late, or continuous adolescent nicotine exposure would alter oral methamphetamine self-administration, extinction, or reinstatement. A total of 164 male and female Sprague-Dawley rats were pretreated with saline or nicotine (0.16, or 0.64 mg/kg, sc) beginning on postnatal day (PD) 25 for 10 consecutive days. On PD …

The Effects Of Selection For High Voluntary Wheel-Running Behavior On Nutrient Canal Abundance And Size, Nicolas Lawrence Schwartz

Electronic Theses, Projects, and Dissertations

Variations in skeletal morphology have often been used to interpret an organism’s overall activity level when direct observation is not possible. Although skeletal change in response to exercise is well documented, the skeleton’s response to mechanical loading is modulated by several factors (e.g. age, hormones, sex). Additionally, variation in skeletal morphology is partially a result of genetic variation, which is rarely accounted for in inferences of locomotor activity from skeletal remains. However, blood flow to long bones serves as a proxy for bone metabolic activity, which can be used to infer locomotor activity. Long bones receive blood from three sources, …

Tragic Mulatta 2.0: A Postcolonial Approximation And Critique Of The Representations Of Bi-Ethnic Women In U.S. Film And Tv, Hadia Nouria Bendelhoum

Electronic Theses, Projects, and Dissertations

This study analyzes the representations of five bi-ethnic women characters in U.S. mass media both before and after U.S. “post-racial” era, to find and expose evidence of the continuity and perpetuation of racist stereotypes against biracial/bi-ethnic women. I utilize a thematic textual analysis, supported by the theories, ideas, and critical views of postcolonial theorists Frantz Fanon, Gayatri Spivak, and Edward Said, and composed of three prominent themes which expose the nature of the representations of lead bi-ethnic characters in current mass media entertainment (TV programs and films). The themes further explored through this project are: bi-ethnicity (one Black parent and …

Fire-Affected Rock In Inland Southern Californian Archaeology: An Investigation Into Diagnostic Utility, Shannon Renee Clarendon

Electronic Theses, Projects, and Dissertations

The post-firing variability of fire-affected rock (FAR) recovered from a stone-cooking platform within a prehistoric stone grill was examined. This examination tested the physical properties of FAR recovered from site CA-SBR-3773, located the Crowder Canyon Archaeological District in San Bernardino County, California. There is a lack of archaeological research in this area of Southern California; however, this project established a fundamental perspective of thermal feature reuse and episodes of firing activity for prehistoric cooking features by examining the physical changes FAR experienced due to various heat exposures. Regional archaeologists often encounter these features as they speckle the landscape of upland …

New Extension Approaches To Serving Agricultural Media In Advancing Farm-Life Safety Communications, Scott Heiberger, James F. Evans

Journal of Extension

The study described here focused on needs and opportunities for Extension to serve agricultural media more fully in addressing new safety risks in agriculture, one of the nation's most hazardous industries. The study was conducted in the context of major broadening of channels used by agricultural media. A mixed-methods approach included a national survey to identify views and suggestions from agricultural journalists about covering farm-life safety. A companion literature review addressed case studies and other research featuring Extension collaborations with media for advancing farm-life safety. Findings revealed expanding opportunities and ideas for Extension personnel, with implications for Extension program areas …

The Effects Of Feed Additives In Beef Finishing Systems And The Effect Of Rumen Degradable Protein Supplementation In Corn Residue Grazing Systems With The Use Of Distillers On Growth Performance, Robert M. Jones

Department of Animal Science: Dissertations, Theses, and Student Research

One receiving trial evaluated the effect of the feed additive monensin (trade name: Rumensin) on steer growth performance in the receiving period while evaluating the effects of two receiving vaccinations on morbidity and mortality of newly received calves. No differences were observed in growth performance, morbidity rate or mortality rate between treatments for the first 28 d of receiving. A finishing trial evaluated the effect of the feed additive ractopamine hydrochloride (trade name: Optaflexx) on feedlot growth performance and carcass characteristics of crossbred yearling steers fed to differing degrees of finish. Feeding ractopamine hydrochloride at 300 mg improved ADG, G:F, …

Perspectives On Video Games As Art, Jeroen Bourgonjon, Geert Vandermeersche, Kris Rutten, Niels Quinten

CLCWeb: Comparative Literature and Culture

In their article "Perspectives on Video Games as Art" Jeroen Bourgonjon, Geert Vndermeer­sche, Kris Rutten and Niels Quinten engage in discussing whether or not video games can be considered a form of art. Although this question has already been discussed elaborately, the debate is guided by many differ­ent and often conflicting positions. The aim of this article is to revisit this debate by mapping out a range of perspectives on video games as art. The authors explore the relation between games and differ­ent definitions and functions of art, different motives of artists, and the potential impact of the arts. The …

Animal Science E-Newsletter, December 2017, University Of Arkansas, Fayetteville. Department Of Animal Sciences

Animal Science e-Newsletter

No abstract provided.

Ant-Inspired Interaction Networks For Decentralized Vehicular Traffic Congestion Control, Andreas Kasprzok

All Dissertations

Mimicking the autonomous behaviors of animals and their adaptability to changing or foreign environments lead to the development of swarm intelligence techniques such as ant colony optimization (ACO) and particle swarm optimization (PSO) now widely used to tackle a variety of optimization problems. The aim of this dissertation is to develop an alternative swarm intelligence model geared toward decentralized congestion avoidance and to determine qualities of the model suitable for use in a transportation network.

A microscopic multi-agent interaction network inspired by insect foraging behaviors, especially ants, was developed and consequently adapted to prioritize the avoidance of congestion, evaluated as …

Survey Of Indoor Air Quality In Residences Of Wic Participants In Lincoln, Nebraska, Eun Hee Kwon

Capstone Experience: Master of Public Health

Since 1992, Women, Infants, and Children at the Lincoln Lancaster County Health Department has provided supplemental food benefits, nutrition information, breastfeeding support, immunization referrals, and dental services to support low-income families and their children. However, statewide, the retention rate has been dropping since 2009, and if this continues, it can result in adverse health outcomes. As part of the Service Learning activities, this study aims to evaluate current services on clients’ experiences and improve their satisfaction by conducting the WIC participant-centered services survey. This cost-effective intervention program has been working successfully, however it does not provide the information of environmental …

Astaxanthin Attenuates Mptp Induced Neurotoxicity And Modulates Cognitive Function In Aged Mice, Beth Grimmig

USF Tampa Graduate Theses and Dissertations

Parkinson’s disease is the second common neurodegenerative disease and is most frequently diagnosed in individuals over 60. There are no available medications that can prevent or restore the loss of neurons that correspond to motor impairments in patients. Identifying novel therapeutic compounds that are capable of slowing and reversing the extensive neurodegeneration that occurs in PD remains an important goal of the field. While basic research has identified potential therapeutic agents, studies often use young model organisms to demonstrate efficacy of the target compound. This approach ignores the impact of the aged CNS on the disease process, and likely contributes …

Animal Welfare Frames: How Social Media Messages Bridge The Gap Between The Protein Industry And Consumers, Olivia Norton

Graduate Theses and Dissertations

The two articles in this thesis used content analysis to analyze and compare animal welfare related website and Twitter content of the top five animal protein producing companies in the United States. In the first article, the animal welfare website content of Cargill, Tyson Foods Inc., Smithfield, JBS® and Sysco were analyzed for persuasive frames, common topics, and key terminology to describe their corporate positions on animal welfare. Sysco’s main page devoted to animal welfare dominated the word count with 1,045 words, while JBS®’s main animal welfare page used only 265 words to communicate the company’s views. The most commonly …

Local Hemostatic Activity Of Psidium Guajava Leaves In Swiss Webster Mice, Cszahreyloren Vitamia, Angga Saputra

Pharmacology and Clinical Pharmacy Research

Psidium guajava (P. guajava) leaves have been empirically used to stop bleeding. Tannin, one of this plant’s secondary metabolites, may contribute to this activity. However, information regarding its pharmacologicy activity was limited. Therefore, this study was performed to evaluate local hemostatic activity of P. guajava leaves. This study used Duke method with male Swiss Webster mice as test animals. The animals were grouped into three i.e., negative control (distilled water), positive control (epinephrin), and P. guajava group. Its tail was cut (2-3 mm) and the bleeding time was calculated. Statistical analysis was performed using   Kruskal-Wallis test and …

Reduction Of Escherichia Coli Surrogates For Shiga Toxin-Producing Escherichia Coli On Beef Cuts By Dipping In Lactic Or Peroxyacetic Acid For Short Or Extended Times And The Effect On Ground Beef Quality, Ashley Rae Mccoy

Department of Animal Science: Dissertations, Theses, and Student Research

Shiga Toxin-producing Escherichia coli (STEC) are adulterants in ground beef. Antimicrobial interventions reduce STEC, but effectiveness may depend on application time and the impact on ground beef quality.

Objectives were to evaluate reductions in rifampicin-resistant E. coli (E. coli^RIF) on beef clod surfaces, and the effect on ground beef quality. Beef clods were sectioned and dipped in 4.5% lactic acid (LA) or 380 ppm peroxyacetic acid (PA) for 15 or 180 s. E. coli^RIF were inoculated (~5.3 log CFU/cm2) onto fat or lean tissue surfaces. Non- inoculated treatments were ground into ~454 g …

Management Strategies For Beef Heifer Development, Shelby Ann Springman

Department of Animal Science: Dissertations, Theses, and Student Research

Four experiments were conducted to determine the impact of development systems, trace mineral source, and trace mineral supplementation on beef heifers. Experiment 1 utilized 300 Angus-based, spring-born heifers to evaluate postweaning heifer development systems on gain, reproductive performance, and feed efficiency as a pregnant heifer. Heifers were blocked by BW and randomly assigned to graze corn residue, upland range, or were fed 1 of 2 diets in a drylot differing in energy levels: high or low. Heifer development system did not impact AI or final pregnancy rates. Development cost per pregnant heifer was not different among treatments. Furthermore, pregnant heifer …

Methane From Lactating Dairy Cattle: Studies For Mitigation, Diurnal Variation, And Role In Energy Metabolism, Jared Vern Judy

Department of Animal Science: Dissertations, Theses, and Student Research

Reducing methane production in dairy cattle has received an increased interest due to environmental concerns associated with its potency as a greenhouse gas. Methane represents lost energy in cattle and reduction may increase animal efficiency and productivity. Experiment 1 evaluated strategies of mitigating methane production in lactating dairy cattle with inclusion of dried distillers grains and solubles (DDGS), DDGS with added corn oil, and DDGS with added calcium sulfate and effects on energy and nitrogen balance. Inclusion of DDGS, corn oil, and calcium sulfate, increased DMI and milk yield. Methane production was reduced with addition of corn oil …

Evaluation Of Corn Condensed Distillers Solubles In Beef Cattle Diets And Grazing Double-Cropped Forages Following Corn Harvest, Benjamin H. Hansen

Department of Animal Science: Dissertations, Theses, and Student Research

Corn condensed distillers solubles (CDS) is a protein and energy dense by-product from dry-milled production of ethanol. Recent oil extraction has posed modifications to the nutrient profile of CDS, suggesting that de-oiled CDS needs to be re-evaluated in beef cattle diets. Three experiments were conducted to evaluate the effects of CDS in high-concentrate diets, forage-based diets, as well as evaluate the effects of CDS on diet digestibility and rumen fermentation parameters in forage-based diets. Feeding CDS in high-concentrate diets up to 20% of the diet DM or in combination with wet distillers grains plus solubles (WDGS) improved performance and resulted …

Parent-Child Interaction Therapy For Children With Autism, Tiffany Thomas

Theses

Autism spectrum disorder (ASD) is a pervasive lifelong developmental delay with a prevalence of 1 in 68 children. This growing epidemic occurs for unspecified causes and researchers continue to explore evidence-based treatments available. Parent–child interaction therapy (PCIT) is a parent training program, initially developed for implementation with typically-developing children. PCIT has shown effectiveness in increasing child compliance, minimizing disruptive problem, improving parent-child relationship satisfaction, and communication. The present study investigated the efficacy of PCIT as an evidence-based practice (EBP) for children with ASD by implementing a non-concurrent multiple baseline design across three participants. Results indicated socially significant increases in child …

Surgical Approaches To Adenocarcinoma Of The Gastroesophageal Junction: The Siewert Ii Conundrum., Andrew M. Brown, Danica N. Giugliano, Adam C. Berger, Michael J. Pucci, Francesco Palazzo

Department of Surgery Faculty Papers

BACKGROUND: The Siewert classification system for gastroesophageal junction adenocarcinoma has provided morphological and topographical information to help guide surgical decision-making. Evidence has shown that Siewert I and III tumors are distinct entities with differing epidemiologic and histologic characteristics and distinct patterns of disease progression, requiring different treatment. Siewert II tumors share some of the characteristics of type I and III lesions, and the surgical approach is not universally agreed upon. Appropriate surgical options include transthoracic esophagogastrectomy, transhiatal esophagectomy, and transabdominal extended total gastrectomy.

PURPOSE: A review of the available evidence of the surgical management of Siewert II tumors is presented. …

Using Remote Cameras To Estimate The Abundance Of Ungulates, Jace C. Taylor

Theses and Dissertations

Many wildlife populations globally are experiencing unprecedented declines, and without accurate and precise estimates of abundance, we will not be able to conserve these vulnerable species. Remote cameras have rapidly advanced as wildlife monitoring tools and may provide accurate and precise estimates of abundance that improve upon traditional methods. Using remote cameras to estimate abundance may be less expensive, less intrusive, less dangerous, and less time consuming than other methods. While it is apparent that remote cameras have a place in the future of wildlife monitoring, research, and management, many questions remain concerning the proper use of these tools. In …

Assembly, Annotation And Optical Mapping Of The A Subgenome Of Avena, Rebekah Ann Lee

Theses and Dissertations

Common oat (Avena) has held a significant place within the global crop community for centuries; although its cultivation has decreased over the past century, its nutritional benefits have recently garnered increased interest for human consumption. No published reference sequences are available for any of the three oat subgenomes. Here we report a quality sequence assembly, annotation and hybrid optical map of the A-genome diploid Avena atlantica Baum and Fedak. The assembly is composed of a total of 3,417 contigs with an N50 of 11.86 Mb and an estimated completeness of 97.6%. This genome sequence will be a valuable research tool …