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2016

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Articles 160141 - 160167 of 160167

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Brain Health: Time Matters In Multiple Sclerosis, Gavin Giovannoni, Helmut Butzkueven, Suhayl Dhib-Jalbut, Jeremy Hobart, Gisela Kobelt, George Pepper, Maria Pia Sormani, Christoph Thalheim, Anthony Traboulsee, Timothy Vollmer Jan 2016

Brain Health: Time Matters In Multiple Sclerosis, Gavin Giovannoni, Helmut Butzkueven, Suhayl Dhib-Jalbut, Jeremy Hobart, Gisela Kobelt, George Pepper, Maria Pia Sormani, Christoph Thalheim, Anthony Traboulsee, Timothy Vollmer

Peninsula Medical School

No abstract provided.


Optimising Self-Care Support For People With Heart Failure And Their Caregivers: Development Of The Rehabilitation Enablement In Chronic Heart Failure (Reach-Hf) Intervention Using Intervention Mapping, Cj Greaves, J Wingham, C Deighan, P Doherty, J Elliott, W Armitage, M Clark, J Austin, C Abraham, J Frost, S Singh, K Jolly, K Paul, L Taylor, S Buckingham, R Davis, H Dalal, Rs Taylor Jan 2016

Optimising Self-Care Support For People With Heart Failure And Their Caregivers: Development Of The Rehabilitation Enablement In Chronic Heart Failure (Reach-Hf) Intervention Using Intervention Mapping, Cj Greaves, J Wingham, C Deighan, P Doherty, J Elliott, W Armitage, M Clark, J Austin, C Abraham, J Frost, S Singh, K Jolly, K Paul, L Taylor, S Buckingham, R Davis, H Dalal, Rs Taylor

School of Nursing and Midwifery

No abstract provided.


Core Outcomes And Common Data Elements In Chronic Subdural Hematoma: A Systematic Review Of The Literature Focusing On Baseline And Peri-Operative Care Data Elements, Aswin Chari, Katie C. Hocking, Ellie Edlmann, Carole Turner, Thomas Santarius, Peter J. Hutchinson, Angelos G. Kolias Jan 2016

Core Outcomes And Common Data Elements In Chronic Subdural Hematoma: A Systematic Review Of The Literature Focusing On Baseline And Peri-Operative Care Data Elements, Aswin Chari, Katie C. Hocking, Ellie Edlmann, Carole Turner, Thomas Santarius, Peter J. Hutchinson, Angelos G. Kolias

Peninsula Medical School

No abstract provided.


Exploring The Relationship Between Childhood Obesity And Proximity To The Coast: A Rural/Urban Perspective, Sophie L. Wood, Philippe R. Demougin, Sahran Higgins, Kerryn Husk, Benedict W. Wheeler, Mathew White Jan 2016

Exploring The Relationship Between Childhood Obesity And Proximity To The Coast: A Rural/Urban Perspective, Sophie L. Wood, Philippe R. Demougin, Sahran Higgins, Kerryn Husk, Benedict W. Wheeler, Mathew White

Peninsula Medical School

Abstract Childhood obesity is one of the 21st century's most serious global health challenges. Research suggests that better access to ‘greenspace’ (e.g. parks) may encourage physical activity and reduce the risk of obesity amongst children. We extend earlier work by considering childhood obesity in relation to proximity to the coast, using data from England's National Child Measurement Programme. Results suggest that although the overall prevalence of childhood obesity is slightly lower at the coast (−0.68% points comparing <1 km to >20 km, p<0.001), the relationship depends on area type. Specifically, although a coastal proximity gradient (lower obesity rates nearer the coast) was found for rural areas and smaller cities and towns, it was not present among large urban conurbations (interaction p-value<0.001). Coastal environments and access to them are changing in many areas, and research to explore potential impacts on child health is warranted.


Anti-Envelope Antibody Responses In Individuals At High Risk Of Hepatitis C Virus Who Resist Infection, R. E. Swann, P. Mandalou, M. W. Robinson, M. M. Ow, S. K.H. Foung, J. Mclauchlan, A. H. Patel, M. E. Cramp Jan 2016

Anti-Envelope Antibody Responses In Individuals At High Risk Of Hepatitis C Virus Who Resist Infection, R. E. Swann, P. Mandalou, M. W. Robinson, M. M. Ow, S. K.H. Foung, J. Mclauchlan, A. H. Patel, M. E. Cramp

Peninsula Medical School

No abstract provided.


The Effectiveness And Micro-Costing Analysis Of A Universal, School-Based, Social–Emotional Learning Programme In The Uk: A Cluster-Randomised Controlled Trial, Vashti Berry, Nick Axford, Sarah Blower, Rod S. Taylor, Rhiannon Tudor Edwards, Kate Tobin, Carys Jones, Tracey Bywater Jan 2016

The Effectiveness And Micro-Costing Analysis Of A Universal, School-Based, Social–Emotional Learning Programme In The Uk: A Cluster-Randomised Controlled Trial, Vashti Berry, Nick Axford, Sarah Blower, Rod S. Taylor, Rhiannon Tudor Edwards, Kate Tobin, Carys Jones, Tracey Bywater

Peninsula Medical School

No abstract provided.


Sphingosine 1-Phosphate Lyase Ablation Disrupts Presynaptic Architecture And Function Via An Ubiquitin- Proteasome Mediated Mechanism, Dn Mitroi, Au Deutschmann, M Raucamp, I Karunakaran, K Glebov, M Hans, J Walter, J Saba, M Gräler, D Ehninger, E Sopova, O Shupliakov, D Swandulla, Echten-Deckert G Van Jan 2016

Sphingosine 1-Phosphate Lyase Ablation Disrupts Presynaptic Architecture And Function Via An Ubiquitin- Proteasome Mediated Mechanism, Dn Mitroi, Au Deutschmann, M Raucamp, I Karunakaran, K Glebov, M Hans, J Walter, J Saba, M Gräler, D Ehninger, E Sopova, O Shupliakov, D Swandulla, Echten-Deckert G Van

Peninsula Medical School

No abstract provided.


Functional Involvement Of Γ-Secretase In Signaling Of The Triggering Receptor Expressed On Myeloid Cells-2 (Trem2), K Glebov, P Wunderlich, I Karaca, J Walter Jan 2016

Functional Involvement Of Γ-Secretase In Signaling Of The Triggering Receptor Expressed On Myeloid Cells-2 (Trem2), K Glebov, P Wunderlich, I Karaca, J Walter

Peninsula Medical School

No abstract provided.


Portable Respiratory Co2 Monitoring Device For Early Screening Of Asthma, Om Prakash Singh Jan 2016

Portable Respiratory Co2 Monitoring Device For Early Screening Of Asthma, Om Prakash Singh

School of Nursing and Midwifery

This paper presents a portable and patient independent respiratory CO2 monitoring device for early screening of asthma. The device is developed incorporation of hardware (Sprint IR CO2 sensor with a sampling rate of 20 Hz, face mask, Atmega 328 microcontroller and graphical liquid crystal display-GLCD) and software (Arduino integrated development environment). The Transistor-Transistor Logic (TTL) communication was used to transmit and receive the signal from the host (microcontroller) to sensor and vice versa. Further, the computation and transmission algorithm was developed to process and display the CO2 signal on GLCD. In addition, the signal processing techniques were used to discriminate …


Social Stories In Mainstream Schools For Children With Autism Spectrum Disorder: A Feasibility Randomised Controlled Trial, David Marshall, Barry Wright, Victoria Allgar, Joy Adamson, Christine Williams, Hannah Ainsworth, Liz Cook, Danielle Varley, Lisa Hackney, Paul Dempster, Shehzad Ali, Dominic Trepel, Moore D Collingridge, Elizabeth Littlewood, Dean Mcmillan Jan 2016

Social Stories In Mainstream Schools For Children With Autism Spectrum Disorder: A Feasibility Randomised Controlled Trial, David Marshall, Barry Wright, Victoria Allgar, Joy Adamson, Christine Williams, Hannah Ainsworth, Liz Cook, Danielle Varley, Lisa Hackney, Paul Dempster, Shehzad Ali, Dominic Trepel, Moore D Collingridge, Elizabeth Littlewood, Dean Mcmillan

Peninsula Medical School

ObjectivesTo assess the feasibility of recruitment, retention, outcome measures and intervention training/delivery among teachers, parents and children. To calculate a sample size estimation for full trial.DesignA single-centre, unblinded, cluster feasibility randomised controlled trial examining Social Stories delivered within a school environment compared with an attentional control.Setting37 primary schools in York, UK.Participants50 participants were recruited and a cluster randomisation approach by school was examined. Participants were randomised into the treatment group (n=23) or a waiting list control group (n=27).Outcome measuresAcceptability and feasibility of the trial, intervention and of measurements required to assess outcomes in a definitive trial.ResultsAn assessment of the questionnaire …


Has The ‘Fast-Track’ Referral System Affected The Route Of Presentation And/Or Clinical Outcomes In Patients With Colorectal Cancer?, Luke Thornton, Harriet Reader, Stevan Stojkovic, Victoria Allgar, Nick Woodcock Jan 2016

Has The ‘Fast-Track’ Referral System Affected The Route Of Presentation And/Or Clinical Outcomes In Patients With Colorectal Cancer?, Luke Thornton, Harriet Reader, Stevan Stojkovic, Victoria Allgar, Nick Woodcock

Peninsula Medical School

No abstract provided.


A Core Curriculum For Sociology In Uk Undergraduate Medical Education, T Collett, L Brooks, S Forrest, J Harden, M Kelly, K Kendall, Stewart S Macbride, M Sbaiti, F Stevenson Jan 2016

A Core Curriculum For Sociology In Uk Undergraduate Medical Education, T Collett, L Brooks, S Forrest, J Harden, M Kelly, K Kendall, Stewart S Macbride, M Sbaiti, F Stevenson

Peninsula Medical School

No abstract provided.


Can’T Count Or Won’T Count? Embedding Quantitative Methods In Substantive Sociology Curricula: A Quasi-Experiment, Malcolm Williams, Luke Sloan, Sin Yi Cheung, Carole Sutton, Sebastian Stevens, Libby Runham Jan 2016

Can’T Count Or Won’T Count? Embedding Quantitative Methods In Substantive Sociology Curricula: A Quasi-Experiment, Malcolm Williams, Luke Sloan, Sin Yi Cheung, Carole Sutton, Sebastian Stevens, Libby Runham

Peninsula Medical School

This paper reports on a quasi-experiment in which quantitative methods (QM) are embedded within a substantive sociology module. Through measuring student attitudes before and after the intervention alongside control group comparisons, we illustrate the impact that embedding has on the student experience. Our findings are complex and even contradictory. Whilst the experimental group were less likely to be distrustful of statistics and appreciate how QM inform social research, they were also less confident about their statistical abilities, suggesting that through ‘doing’ quantitative sociology the experimental group are exposed to the intricacies of method and their optimism about their own abilities …


A Qualitative Study Of Diverse Providers' Behaviour In Response To Commissioners, Patients And Innovators In England: Research Protocol, Rod Sheaff, Joyce Halliday, Mark Exworthy, Pauline Allen, Russell Mannion, Sheena Asthana, Alex Gibson, Jonathan Clark Jan 2016

A Qualitative Study Of Diverse Providers' Behaviour In Response To Commissioners, Patients And Innovators In England: Research Protocol, Rod Sheaff, Joyce Halliday, Mark Exworthy, Pauline Allen, Russell Mannion, Sheena Asthana, Alex Gibson, Jonathan Clark

Peninsula Medical School

Introduction: The variety of organisations providing National Health Service (NHS)-funded services in England is growing. Besides NHS hospitals and general practitioners (GPs), they include corporations, social enterprises, voluntary organisations and others. The degree to which these organisational types vary, however, in the ways they manage and provide services and in the outcomes for service quality, patient experience and innovation, remains unclear. This research will help those who commission NHS services select among the different types of organisation for different tasks. Research questions: The main research questions are how organisationally diverse NHS-funded service providers vary in their responsiveness to patient choice, …


Chromosomal Microarray Testing In Adults With Intellectual Disability Presenting With Comorbid Psychiatric Disorders, Kate Wolfe, André Strydom, Deborah Morrogh, Jennifer Carter, Peter Cutajar, Mo Eyeoyibo, Angela Hassiotis, Jane Mccarthy, Raja Mukherjee, Dimitrios Paschos, Nagarajan Perumal, Stephen Read, Rohit Shankar, Saif Sharif, Suchithra Thirulokachandran, Johan H. Thygesen, Christine Patch, Caroline Ogilvie, Frances Flinter, Andrew Mcquillin, Nick Bass Jan 2016

Chromosomal Microarray Testing In Adults With Intellectual Disability Presenting With Comorbid Psychiatric Disorders, Kate Wolfe, André Strydom, Deborah Morrogh, Jennifer Carter, Peter Cutajar, Mo Eyeoyibo, Angela Hassiotis, Jane Mccarthy, Raja Mukherjee, Dimitrios Paschos, Nagarajan Perumal, Stephen Read, Rohit Shankar, Saif Sharif, Suchithra Thirulokachandran, Johan H. Thygesen, Christine Patch, Caroline Ogilvie, Frances Flinter, Andrew Mcquillin, Nick Bass

Peninsula Medical School

Chromosomal copy-number variations (CNVs) are a class of genetic variants highly implicated in the aetiology of neurodevelopmental disorders, including intellectual disabilities (ID), schizophrenia and autism spectrum disorders (ASD). Yet the majority of adults with idiopathic ID presenting to psychiatric services have not been tested for CNVs. We undertook genome-wide chromosomal microarray analysis (CMA) of 202 adults with idiopathic ID recruited from community and in-patient ID psychiatry services across England. CNV pathogenicity was assessed using standard clinical diagnostic methods and participants underwent comprehensive medical and psychiatric phenotyping. We found an 11% yield of likely pathogenic CNVs (22/202). CNVs at recurrent loci, …


Patient- And Carer-Held Health Records: Can They Improve Annual Health Checks For Patients With Learning Disability?, Rohit Shankar, Guy Bradley-Smith, Philip Brigham, John Devapriam, Amy Osborne, Sharon Axby Jan 2016

Patient- And Carer-Held Health Records: Can They Improve Annual Health Checks For Patients With Learning Disability?, Rohit Shankar, Guy Bradley-Smith, Philip Brigham, John Devapriam, Amy Osborne, Sharon Axby

Peninsula Medical School

No abstract provided.


Lone Parents’ Experiences Of Higher Education, Lucy Spowart Jan 2016

Lone Parents’ Experiences Of Higher Education, Lucy Spowart

Peninsula Medical School

In the UK, close to one in four children are cared for by a lone parent (Policy Research Institute, 2007:8). The specific needs of students with parental responsibilities have been largely ignored by widening participation agendas, despite research evidence suggesting that this group is increasing in number (Hinton-Smith, 2012; Moreau, 2011). One of the key challenges at Plymouth (and elsewhere) is that data classifying students as parents is not collected on application or enrolment, and as a consequence this group remain largely invisible. Student Finance England no longer offers specific funding for single parents adding to the difficulties in identifying …


Learning Organizations: Panacea Or Irrelevance?, Rod Sheaff Jan 2016

Learning Organizations: Panacea Or Irrelevance?, Rod Sheaff

Peninsula Medical School

No abstract provided.


A Multinational Cross-Sectional Survey Of The Management Of Patient Medication Adherence By European Healthcare Professionals, W Clyne, C Mshelia, S Mclachlan, P Jones, Et Al Jan 2016

A Multinational Cross-Sectional Survey Of The Management Of Patient Medication Adherence By European Healthcare Professionals, W Clyne, C Mshelia, S Mclachlan, P Jones, Et Al

Peninsula Medical School

Objectives To examine which interventions healthcare professionals use to support patients with taking medicines and their perceptions about the effectiveness of those actions. Design Cross-sectional multinational study. Setting Online survey in Austria, Belgium, England, France, Germany, Hungary, The Netherlands, Poland, Portugal and Switzerland. Participants A total of 3196 healthcare professionals comprising doctors (855), nurses (1047) and pharmacists (1294) currently registered and practising in primary care and community settings. Main outcome measures Primary outcome: Responses to the question ‘I ask patients if they have missed any doses of their medication’ for each profession and in each country. Secondary outcome: Responses to …


Deshazer, M.K.Mammographies: The Cultural Discourses Of Breast Cancer Narratives. Michigan: University Of Michigan Press. 2013. 239 Pp £28.50 Isbn 978–0472118823 (Hbk), J Tredinnick‐Rowe Jan 2016

Deshazer, M.K.Mammographies: The Cultural Discourses Of Breast Cancer Narratives. Michigan: University Of Michigan Press. 2013. 239 Pp £28.50 Isbn 978–0472118823 (Hbk), J Tredinnick‐Rowe

Peninsula Medical School

No abstract provided.


Postpartum Regression Of A Presumed Cavernous Meningioma, See Yung Phang, Peter Whitfield Jan 2016

Postpartum Regression Of A Presumed Cavernous Meningioma, See Yung Phang, Peter Whitfield

Peninsula Medical School

Meningiomas are known to be more common in females than males. They are also known in rare cases to grow in size during pregnancy, which can complicate its management. We describe a 31-year-old Caucasian woman who presented with blurring of her vision and diplopia during the third trimester of her pregnancy. Magnetic resonance imaging (MRI) showed a small left cavernous sinus meningioma. The patient was treated conservatively until her uncomplicated delivery. A postpartum MRI scan showed complete regression of the suspected meningioma. Currently the patient is contemplating a further pregnancy.


Message, P Laxminarayana Rao Dr Jan 2016

Message, P Laxminarayana Rao Dr

Manipal Journal of Nursing and Health Sciences

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Problems, Awareness And Practices Of Caregivers Of Epileptic Patients Regarding Home Management Of Epilepsy, Deepika Chauhan Ms, Manisha Kumari Ms, Priya Portion Ms, Vanita Kumari Ms Jan 2016

Problems, Awareness And Practices Of Caregivers Of Epileptic Patients Regarding Home Management Of Epilepsy, Deepika Chauhan Ms, Manisha Kumari Ms, Priya Portion Ms, Vanita Kumari Ms

Manipal Journal of Nursing and Health Sciences

Background: Epilepsy is the fourth most common neurological disorder which affects people of all ages. Inappropriate management during seizure episodes among the epileptic patients can lead to complications. That is why, it is important for caregivers of epileptic patients to know about the disease and its management. Objective: To assess the problems, awareness and practices of caregivers of epileptic patients regarding home management of epilepsy. Material and Methods: A descriptive approach was employed. A total of 60 subjects (caregivers) visiting neurology OPD of tertiary care hospital in the month of April 2014 were enrolled. Information profile, details and information regarding …


Comparison Of Body Temperature Of Elderly With Adult In South India, Anu Baby Ms, Sulochana B Ms, Latha T Ms Jan 2016

Comparison Of Body Temperature Of Elderly With Adult In South India, Anu Baby Ms, Sulochana B Ms, Latha T Ms

Manipal Journal of Nursing and Health Sciences

Background: Ageing is a gradual process, characterized by continued development and maturation. Every year there is an increase in the elderly population. Body temperature is an indicator of health status. However, thermoregulatory function is thought to decline with ageing. Therefore, it is significant to know the normal body temperature in elderly. Objective: Compare the normal body temperature among adults and elderly using Omron MC-510 tympanic thermometer. Methods: A cross sectional descriptive survey design was adopted for the study. Elderly (n=360) and adults (n=360) were screened for the presence of factors affecting core body temperature. Readings were recorded using Omron MC-510 …


Impact Of Apgar Score On Asthma Control Among Patients With Bronchial Asthma At Sri Ramachandra Hospital, Porur, Chennai, M Malarvizhi Ms, M Bhavani Ms Jan 2016

Impact Of Apgar Score On Asthma Control Among Patients With Bronchial Asthma At Sri Ramachandra Hospital, Porur, Chennai, M Malarvizhi Ms, M Bhavani Ms

Manipal Journal of Nursing and Health Sciences

Introduction: Early identification and commencement of the treatment process prevents the impact of illness, morbidity, and mortality of bronchial asthma. Hence, nurses and the health care professionals should educate the patients and the family members about the disease process in detail. Objective: To identify the impact of APGAR (Activities, Persistence, TriGGers, Adherence to asthma medications, Response to therapy) score on asthma control among patients with bronchial asthma and find the association of APGAR with selected demographic variables. Methods: The study was conducted in Chest OPD adopting a quantitative study design at Sri Ramachandra Hospital, Chennai, and Tamil Nadu. Sixty patients …


A Review Of The Effect Of Occupational Experience Of Patient Death And Death Situations On Nurses, Rhoda Suubi Muliira, Joshua Kanaabi Muliira Jan 2016

A Review Of The Effect Of Occupational Experience Of Patient Death And Death Situations On Nurses, Rhoda Suubi Muliira, Joshua Kanaabi Muliira

Manipal Journal of Nursing and Health Sciences

Background: Impacts of regular occupational exposure and experience of patient death on nurses’ professional quality of life and well-being. Despite the impacts, it has not yet been adequately addressed by professional training, research and by employers of nurses. Purpose: To analyze the impacts of occupational exposure, experience of patient death and death situations on nurses’ professional quality of life and recommend strategies to curtail them. Methods: Studies were retrieved from three databases CINAHL, SCOPUS, MEDLINE and reference lists of relevant journal publications. Results: The findings show that the impact of experience of patient death on nurses positively or negatively depending …


Amniotic Band Sequence With Clubfoot In A Neonate: A Case Report, Maria Pais Ms, Leslie E. Lewis Dr, Ramesh Bhat Y Dr, Jayashree P Dr Jan 2016

Amniotic Band Sequence With Clubfoot In A Neonate: A Case Report, Maria Pais Ms, Leslie E. Lewis Dr, Ramesh Bhat Y Dr, Jayashree P Dr

Manipal Journal of Nursing and Health Sciences

Amniotic band sequence (ABS) refers to a variable spectrum of congenital anomalies that occur in association with fibrous amniotic bands. The abnormalities are typically limited to external structures, most frequently to limbs and digits resulting in digital amputation and constriction rings. Sometimes ABS may be associated with visceral abnormalities and clubfoot. We report a case of ABS with clubfoot in a neonate