Digital Commons Network^™

Multiple Perspectives Community Engagement Assessment Model, Sally Blomstrom, Barbara Hayford, Lori A. Mumpower, Andrelle Bobinsky

Publications

We propose a multiple perspectives assessment model for community engagement. The assessment model was developed for a service-learning project. The multiple perspectives included in the model were those from the community partner, the faculty member, students, and the associate director from the Center for Teaching and Learning Excellence (CTLE). The model assessed the effectiveness of the service-learning project using qualitative reflections and quantitative data. Assessment from each perspective produced positive results in the improvement areas of assignment instructions, pedagogy, process, and deliverables. Generalizability may be limited because this project is ongoing with the same representatives from the community partner, CTLE, …

Design And Commissioning Of A Community Scale Solar Powered Membrane-Based Water Purification System In Haiti, Shavin Pinto, Yung Wong, Kyle Fennesy, Yan Tang, Marc Compere

Publications

This paper presents the design and commissioning of a solar powered water purification system at the Ryan Epps Home for Children (REHC) in Michaud, Haiti. This system supplies clean drinking water to the 200 children who live and go to school at REHC and also to the community in the form of a micro-business. This micro-business is the mechanism for income generation for sustainable system operation. The purifier uses a three stage filtration system with a disc-type sediment filter, a 0.1 micron ultrafiltration membrane, and an ultraviolet light for disinfection. The backwash cycle extends the life of the ultrafiltration membrane …

Audio Tours Of Fish: Angling For An Effective Mediated Speech, Sally Blomstrom, Barbara Hayford, Lori A. Mumpower

Publications

Public speaking is a course required in many degree programs traditionally taught in a face to face setting. Online and hybrid courses are now offered by many institutions in addition to traditional courses, and they are more likely to include mediated speech assignments. Mediated speaking situations include webinars, videoconferences, video recordings of speeches on DVD or YouTube, and other options that students may well find themselves using in their personal and professional communication. Online and some hybrid courses assign mediated speaking situations for the submission of speeches, not as a genre unto itself. In traditional face to face public speaking …

Lazer: Distributed Memory-Efficient Assembly Of Large-Scale Genomes, Sayan Goswami, Arghya Kusum Das, Richard Platania, Kisung Lee, Seung Jong Park

Computer Science Faculty Research & Creative Works

Genome sequencing technology has witnessed tremendous progress in terms of throughput as well as cost per base pair, resulting in an explosion in the size of data. Consequently, typical sequence assembly tools demand a lot of processing power and memory and are unable to assemble big datasets unless run on hundreds of nodes. In this paper, we present a distributed assembler that achieves both scalability and memory efficiency by using partitioned de Bruijn graphs. By enhancing the memory-to-disk swapping and reducing the network communication in the cluster, we can assemble large sequences such as human genomes (452 GB) on just …

The Role Of Pre-Existing Basement Fabrics In The Initiation Of Continental Rifting: The Okavango Rift Zone, Botswana, Angelica Alvarez Naranjo

Doctoral Dissertations

"Integrated geophysical, remote sensing, and field investigations of the Okavango Rift Zone (ORZ), Botswana indicate that a feedback between optimum-oriented basement structures and fluid flow influence the nucleation and growth of continental rifts in their incipient stages. The ORZ, the youngest rift of the East African Rift System, occurs within a Proterozoic inter-cratonic suture zone - the NE-trending Precambrian Damara/Ghanzi-Chobe orogenic belts. The Pleistocene to Holocene ORZ forms a ~450 km long and ~100 km wide half-graben bounded by NE-trending normal faults. Basement units within the Damara/Ghanzi-Chobe orogenic belts exhibit a well-developed NE-trending linear fabric (045-065) defined by parallel limbs …

Activation Of Signal Transduction Pathways During Hepatic Oncogenesis, W Chung, M Kim, S De La Monte, L Longato, R Carlson, B L. Slagle, X Dong, J R. Wands

Faculty, Staff and Students Publications

BACKGROUND AND AIMS: Understanding the molecular pathogenesis of hepatocellular carcinoma (HCC) is essential to identify therapeutic targets. A hepatitis B virus (HBV) related double transgenic murine model was developed. METHODS: Liver specific expression of HBV X protein (HBx) and insulin receptor substrate 1 (IRS1) was achieved and transgenic mice were followed from birth to age 21 months. Liver and tumor tissue were assessed for histologic changes as well as activation of signal transduction pathways by qRT-PCR and multiplex ELISA protein assays. RESULTS: Overexpression of HBx and IRS1 stimulates liver cell proliferation in the double transgenic mice. Only the male mice …

Applications Of Simulation And Optimization Techniques In Optimizing Room And Pillar Mining Systems, Angelina Konadu Anani

Doctoral Dissertations

"The goal of this research was to apply simulation and optimization techniques in solving mine design and production sequencing problems in room and pillar mines (R&P). The specific objectives were to: (1) apply Discrete Event Simulation (DES) to determine the optimal width of coal R&P panels under specific mining conditions; (2) investigate if the shuttle car fleet size used to mine a particular panel width is optimal in different segments of the panel; (3) test the hypothesis that binary integer linear programming (BILP) can be used to account for mining risk in R&P long range mine production sequencing; and (4) …

Evaluating Of Scale-Up Methodologies Of Gas-Solid Spouted Beds For Coating Triso Nuclear Fuel Particles Using Advanced Measurement Techniques, Neven Y. Ali

Doctoral Dissertations

"The work focuses on implementing for the first time advanced non-invasive measurement techniques to evaluate the scale-up methodology of gas-solid spouted beds for hydrodynamics similarity that has been reported in the literature based on matching dimensionless groups and the new mechanistic scale up methodology that has been developed in our laboratory based on matching the radial profile of gas holdup since the gas dynamics dictate the hydrodynamics of the gas-solid spouted beds. These techniques are gamma-ray computed tomography (CT) to measure the cross-sectional distribution of the phases' holdups and their radial profiles along the bed height and radioactive particle tracking …

Blended Learning In Chemistry Laboratory Courses: Enhancing Learning Outcomes And Aligning Student Needs With Available Resources, Shayna Brianne Burchett

Doctoral Dissertations

"Freshman science courses are intended to prepare students for the rigor and expectations of subsequent college science. While secondary education aims to prepare students for the college curriculum, many incoming freshman lack the sense of responsibility for their own learning that is essential for success in a college-level course. The freshman general-chemistry laboratory course at Missouri University of Science and Technology (Missouri S&T) was identified as a bottleneck course with a demand beyond accommodation capacity. To address the bottleneck and develop a sense of learner responsibility, a decision was made to investigate laboratory course delivery strategies. As a result of …

Microwave Material Characterization Of Alkali-Silica Reaction (Asr) Gel In Cementitious Materials, Ashkan Hashemi

Doctoral Dissertations

"Since alkali-silica reaction (ASR) was recognized as a durability challenge in cement-based materials over 70 years ago, numerous methods have been utilized to prevent, detect, and mitigate this issue. However, quantifying the amount of produced ASR byproducts (i.e., ASR gel) in-service is still of great interest in the infrastructure industry. The overarching objective of this dissertation is to bring a new understanding to the fundamentals of ASR formation from a microwave dielectric property characterization point-of-view, and more importantly, to investigate the potential for devising a microwave nondestructive testing approach for ASR gel detection and evaluation. To this end, a comprehensive …

Adaptive Filters For Sparse System Identification, Jianming Liu

Doctoral Dissertations

"Sparse system identification has attracted much attention in the field of adaptive algorithms, and the adaptive filters for sparse system identification are studied. Firstly, a new family of proportionate normalized least mean square (PNLMS) adaptive algorithms that improve the performance of identifying block-sparse systems is proposed. The main proposed algorithm, called block-sparse PNLMS (BS-PNLMS), is based on the optimization of a mixed ℓ_2,1 norm of the adaptive filter's coefficients. A block-sparse improved PNLMS (BS-IPNLMS) is also derived for both sparse and dispersive impulse responses. Meanwhile, the proposed block-sparse proportionate idea has been extended to both the proportionate affine projection …

On The Spheroidal Graphite Growth And The Austenite Solidification In Ductile Irons, Jingjing Qing

Doctoral Dissertations

"Evolutions of austenite and nodular/spheroidal graphite particles during solidifications of ductile irons were experimentally investigated. Spheroidal graphite particle and austenite dendrite were found nucleated independently in liquid. Austenite dendrite engulfed the spheroidal graphite particles after contact and an austenite shell formed around a spheroidal graphite particle. The graphite diameter at which the austenite shell closed around nodule was determined. Statistically determined graphite size distributions indicated multiple graphite nucleation events during solidification.

Structures in a graphite nodule varied depending on the growth stages of the nodule in ductile iron. Curved graphene layers appearing as faceted growth ledges swept circumferentially around the …

Study Of Heat Transfer Phenomenon During Natural Convection, Muhammad Yousaf

Doctoral Dissertations

"The purpose of the present study was to numerically investigate the effects of the roughness elements on the heat transfer during natural convection. A computational algorithm was developed based on the Lattice Boltzmann method to conduct numerical study in two-dimensional rectangular cavities and Rayleigh-Bénard cell. A single relaxation time Bhatnagar-Gross-Krook model of Lattice Boltzmann method was used to solve the coupled momentum and energy equations in two-dimensional lattices. Computational model was validated against previous benchmark solutions, and a good agreement was found to exist. A Newtonian fluid of Prandtl (Pr) number 1.0 was considered for this numerical study. The range …

Model Based Fault Diagnosis And Prognosis Of Class Of Linear And Nonlinear Distributed Parameter Systems Modeled By Partial Differential Equations, Jia Cai

Doctoral Dissertations

"With the rapid development of modern control systems, a significant number of industrial systems may suffer from component failures. An accurate yet faster fault prognosis and resilience can improve system availability and reduce unscheduled downtime. Therefore, in this dissertation, model-based prognosis and resilience control schemes have been developed for online prediction and accommodation of faults for distributed parameter systems (DPS). First, a novel fault detection, estimation and prediction framework is introduced utilizing a novel observer for a class of linear DPS with bounded disturbance by modeling the DPS as a set of partial differential equations.

To relax the state measurability …

Lifetime And Effectiveness Evaluation Of Ceramic Pot Filters, Carlo Salvinelli

Doctoral Dissertations

"Poor water quality is a major contributing factor to disease in developing countries. Ceramic pot filters (CPFs) represent an effective and sustainable technology for poor communities, but the characterization of CPF lifetimes is on-going, and the water production seems to be the limiting factor. This dissertation describes laboratory and field investigations conducted to characterize the parameters that impact CPF effectiveness and lifetime in terms of water production and treatment efficacy, both under controlled and real use conditions.

CPF initial flow rate is the most common quality control parameter, but it may not be representative of the long-term effectiveness of the …

A Control Theoretic Approach For Security Of Cyber-Physical Systems, Haifeng Niu

Doctoral Dissertations

"In this dissertation, several novel defense methodologies for cyber-physical systems have been proposed. First, a special type of cyber-physical system, the RFID system, is considered for which a lightweight mutual authentication and ownership management protocol is proposed in order to protect the data confidentiality and integrity. Then considering the fact that the protection of the data confidentiality and integrity is insufficient to guarantee the security in cyber-physical systems, we turn to the development of a general framework for developing security schemes for cyber-physical systems wherein the cyber system states affect the physical system and vice versa. After that, we apply …

Dft Investigations Of Hydrogen Storage Materials, Gang Wang

Doctoral Dissertations

"Hydrogen serves as a promising new energy source having no pollution and abundant on earth. However the most difficult problem of applying hydrogen is to store it effectively and safely, which is smartly resolved by attempting to keep hydrogen in some metal hydrides to reach a high hydrogen density in a safe way. There are several promising metal hydrides, the thermodynamic and chemical properties of which are to be investigated in this dissertation.

Sodium alanate (NaAlH₄) is one of the promising metal hydrides with high hydrogen storage capacity around 7.4 wt. % and relatively low decomposition temperature of …

High-Voltage-Gain Dc-Dc Power Electronic Converters -- New Topologies And Classification, Bhanu Prashant Reddy Baddipadiga

Doctoral Dissertations

"This dissertation proposes two new high-voltage-gain dc-dc converters for integration of renewable energy sources in 380/400V dc distribution systems. The first high-voltage-gain converter is based on a modified Dickson charge pump voltage multiplier circuit. The second high-voltage-gain converter is based on a non-inverting diode-capacitor voltage multiplier cell. Both the proposed converters offer continuous input current and low voltage stress on switches which make them appealing for applications like integration of renewable energy sources. The proposed converters are capable for drawing power from a single source or two sources while having continuous input current in both cases. Theoretical analysis of the …

Uncertainty Quantification Applied To The Analysis And Design Of A Hypersonic Inflatable Aerodynamic Decelerator For Spacecraft Reentry, Andrew J. Brune

Doctoral Dissertations

"The primary objective of this research is to investigate the uncertainty in the multidisciplinary analysis of a Hypersonic Inflatable Aerodynamic Decelerator configuration for Mars entry, subject to uncertainty sources in the high-fidelity computational models and the operating conditions. Efficient uncertainty quantification methods based on stochastic expansions are applied to the analysis of the hypersonic flowfield, fluid-structure interaction, and flexible thermal protection system response of a deformable inflatable decelerator. Uncertainty analysis is first applied to the hypersonic flowfield simulations to quantify the uncertainty in the surface convective and radiative heat flux, pressure, and shear stress of a fixed inflatable decelerator, subject …

Development And Evaluation Of A Coaxial Cable Sensing System For Co₂ Sequestration Wellbore Integrity Monitoring, Yurong Li

Doctoral Dissertations

"Downhole monitoring plays a crucial part in geological carbon dioxide (₂) sequestration. Various downhole monitoring technologies have been explored and applied, but they are either expensive or have system longevity issues. To address this issue, a robust and cost-effective downhole sensing system based on distributed coaxial cable sensors is developed and evaluated in laboratory, and a numerical simulation with staged finite element model is conducted to study the feasibility of using the coaxial cable sensing system for monitoring and evaluation of wellbore stability during CO₂ injection.

The real-time distributed sensing system is composed of Fabry-Perot interferometer based …

Advancing Microalgae Culturing Via Bubble Dynamics, Mass Transfer, And Dynamic Growth Investigations, Aastha Ojha

Doctoral Dissertations

"The major hindrances to large scale cultivation of microalgae are the problems associated with the design, operation, and scale-up of airlift photobioreactors (PBRs), due to a lack of a comprehensive understanding of the gas-liquid interaction process in real microalgae cultures. Thus, the overall objective of this work is to advance the fundamental understanding of microalgae culturing via gas holdup, bubble dynamics, mass transfer, and dynamic growth investigations.

First, a four-point optical fiber probe technique was employed to study the local gas holdup, and bubble dynamics properties such as bubble passage frequency, chord length and bubble velocity distribution, and interfacial area …

Development Of Implants Composed Of Bioactive Materials For Bone Repair, Wei Xiao

Doctoral Dissertations

"The purpose of this Ph.D. research was to address the clinical need for synthetic bioactive materials to heal defects in non-loaded and loaded bone. Hollow hydroxyapatite (HA) microspheres created in a previous study were evaluated as a carrier for controlled release of bone morphogenetic protein-2 (BMP2) in bone regeneration. New bone formation in rat calvarial defects implanted with BMP2-loaded microspheres (43%) was significantly higher than microspheres without BMP2 (17%) at 6 weeks postimplantation. Then hollow HA microspheres with a carbonate-substituted composition were prepared to improve their resorption rate. Hollow HA microspheres with ~12 wt. % of carbonate showed significantly higher …

Efficient Time-Dependent System Reliability Analysis, Zhifu Zhu

Doctoral Dissertations

"Engineering systems are usually subjected to time-variant loads and operate under time-dependent uncertainty; system performances are therefore time-dependent. Accurate and efficient estimate of system reliability is crucial for decision makings on system design, lifetime cost estimate, maintenance strategy, etc. Although significant progresses have been made in time-independent reliability analysis for components and systems, time-dependent system reliability methodologies are still limited. This dissertation is motivated by the need of accurate and effective reliability prediction for engineering systems under time-dependent uncertainty. Based on the classic First and Second Order Reliability Method (FORM and SORM), a system reliability method is developed for multidisciplinary …

Innovative Techniques For Seismic-Resistant Bridge Columns Under Ground Motion Excitations, Ayman A. Moustafa

Doctoral Dissertations

“This dissertation provides innovative alternative solutions for replacing conventional reinforced concrete columns. The proposed columns displayed enhanced seismic resistance and properties compared to their counterpart conventional columns. Two main techniques were followed and proposed to develop seismic-resistant columns. The first technique utilized rubberized concrete to internally enhance energy dissipation and damping. Materials testing of rubberized concrete with scrap tire replacement of fine aggregates were performed to evaluate its dynamic properties. Shaking table testing of a rubberized concrete column was performed and the behavior was compared to that of the conventional one. The rubberized column showed an increase of 16% in …

Association Of Urinary Phthalates With Self-Reported Eye Affliction/Retinopathy In Individuals With Diabetes: National Health And Nutrition Examination Survey, 2001-2010, Manju Mamtani, Joanne E. Curran, John Blangero, Hemant Kulkarni

School of Medicine Publications

Background. An epidemiological association between exposure to phthalates and type 2 diabetes (T2D) is known. However, the potential role of environmental phthalates in the complications of T2D is unknown. Methods. Using data from the National Health and Nutrition Examination Survey (NHANES) 2001-2010, we studied the association of 12 urinary phthalate metabolites with self-reported eye affliction/retinopathy in 1,004 participants with diabetes. Data from retinal imaging was used to validate this outcome. Independence of the phthalates→T2D association was studied by adjusting for age, sex, race, marital status, educational attainment, poverty income ratio, physical activity, glycated hemoglobin levels, total serum cholesterol, serum high-density …

Locations Of Physical Activity As Assessed By Gps In Young Adolescents., Jordan A. Carlson, Jasper Schipperijn, Jacqueline Kerr, Brian E. Saelens, Loki Natarajan, Lawrence D. Frank, Karen Glanz, Terry L. Conway, Kelli L. Cain, James F. Sallis, J E. Chapman

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: To compare adolescents' physical activity at home, near home, at school, near school, and at other locations.

METHODS: Adolescents (N = 549) were ages 12 to 16 years (49.9% girls, 31.3% nonwhite or Hispanic) from 447 census block groups in 2 US regions. Accelerometers and Global Positioning System devices assessed minutes of and proportion of time spent in moderate to vigorous physical activity (MVPA) in each of the 5 locations. Mixed-effects regression compared MVPA across locations and demographic factors.

RESULTS: Forty-two percent of adolescents' overall MVPA occurred at school, 18.7% at home, 18.3% in other (nonhome, nonschool) locations, and …

Contraceptive Provision To Adolescent Females Prescribed Teratogenic Medications., Stephani L. Stancil, Melissa K. Miller, Holley Briggs, Daryl Lynch, Kathy Goggin, Gregory Kearns

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND AND OBJECTIVES: Rates of adult women receiving contraceptive provision when simultaneously prescribed a known teratogen are alarmingly low. The prevalence of this behavior among pediatric providers and their adolescent patients is unknown. The objective of this study was to describe pediatric provider behaviors for prescribing teratogens concurrently with counseling, referral, and/or prescribing of contraception (collectively called contraceptive provision) in the adolescent population.

METHODS: A retrospective review was conducted examining visits in 2008-2012 by adolescents aged 14 to 25 years in which a known teratogen (US Food and Drug Administration pregnancy risk category D or X) was prescribed. The electronic …

Allergic Diseases And Internalizing Behaviors In Early Childhood., Maya K. Nanda, Grace K. Lemasters, Linda Levin, Marc E. Rothenberg, Amal H. Assa'ad, Nicholas Newman, David Bernstein, Gurjit Khurana-Hershey, James E. Lockey, Patrick H. Ryan

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND AND OBJECTIVES: The relationship between allergic diseases and internalizing disorders has not been well characterized with regard to multiple allergic diseases or longitudinal study. The objective of this study was to examine the association between multiple allergic diseases in early childhood with validated measures of internalizing disorders in the school-age years.

METHODS: Children enrolled in the Cincinnati Childhood Allergy and Air Pollution Study underwent skin testing and examinations at ages 1, 2, 3, 4, and 7 years. At age 7, parents completed the Behavior Assessment System for Children, Second Edition (BASC-2), a validated measure of childhood behavior and emotion. …

Introduction To Bioethics Special Supplement V: Ethical Issues In Genomic Testing Of Children., John D. Lantos

Manuscripts, Articles, Book Chapters and Other Papers

Next-generation genome sequencing of children is one of the most promising and most challenging new technologies in pediatrics. On the one hand, it offers the hope that we will be able to diagnose rare conditions that were previously impossible to diagnose, which, in turn, might lead to new treatments. On the other hand, the technology for sequencing presents daunting problems of interpretation. It is problematic to conduct the research necessary to characterize the pathogenicity of those variants at the same time that we are using them to guide the clinical care of children who have complex medical problems. It is …

The Challenge Of Analyzing The Results Of Next-Generation Sequencing In Children., Isabelle Thiffault, John Lantos

Manuscripts, Articles, Book Chapters and Other Papers

In recent years, next-generation sequencing technologies have revolutionized approaches to genetic studies. Whole-exome or whole-genome sequencing allows diagnoses in many patients who have complex phenotypes and unusual clinical presentations. As genomic and exomic testing expands in both the research and clinical settings, pediatricians will need to understand the technology of next-generation sequencing and the complexity of interpreting genomic variants relevant to patient phenotypic features. This article briefly explains the technology by which genomes are sequenced and discusses some of the complexity related to interpreting genomic variants. We conclude with some thoughts on the clinical applications of such testing.