Digital Commons Network^™

Social Capital In Online Courses, Thomas Mays

Mid-Western Educational Researcher

As colleges and universities increase their online course offerings, student social experiences in online learning environments require further examination, specifically for nonresidential students who may already be less integrated into college social networks. A social capital framework was used to guide this qualitative study of 17 nonresidential students and two faculty from two regional campuses of a public Midwestern university. Student participants reported different experiences in online courses compared to face-to-face (FTF) courses, expressly reporting the development of fewer friendships in their online courses, a lack of a sense of community, and an increase in the mechanical nature of their …

Implementing An Evidence-Based Reflective Teaching Cycle: Using Scholarly Research In Curriculum Design, Rachel Ragland

Mid-Western Educational Researcher

Course curriculum design using a research-teaching connection and reflective teaching is presented. The research-teaching connection is expanded to a three stage research-teaching-research cycle and reflection is expanded to include both faculty and students. Traditional disciplinary educational research was used to inform the design of the curriculum, and Scholarship of Teaching and Learning (SoTL) research was used to measure the success of the course design in achieving its objectives for student learning. The objective of the course redesign was to better engage students in applying the authentic disciplinary practices of the field of history teacher preparation. The research project documented how …

New Teacher Perceptions Of Induction Programs: A Study Of Open-Ended Commentary, Nicole V. Williams, John C. Gillham, Leslie A. Evans

Mid-Western Educational Researcher

The purpose of this study was to learn if teachers believe their experiences with the Ohio Resident Educator Program (OREP) improved their ability to meet the Ohio Standards for the Teaching Profession (OSTP). Two hundred forty-five teachers voluntarily participated in a thirty-three question Likert-based survey with seven open-ended comment sections. For this study, the researchers analyzed the Likert-based survey responses through basic descriptive analysis and ANOVAs and the 456 comments from the seven open-ended comment sections regarding the seven OSTP standards through grounded theory. The findings indicate that the beginning teachers do not believe the Ohio Resident Educator Program improved …

An Exploratory, Descriptive Study Of The Attitudes Of Instructors And Students Toward The Use Of Asynchronous Online Discussion At A Female University In Saudi Arabia, Hamed A. Alshahrani, David A. Walker

Mid-Western Educational Researcher

This exploratory, descriptive study examined instructor and female student attitudes toward asynchronous online discussion (AOD) in Saudi Arabia. Preliminary results, derived from an attitudinal-based survey, indicated that, in aggregate, instructors and students had positive attitudes toward using AOD at a female institution of higher education in Saudi Arabia. Inferentially, the two groups differed in their perceptions of using AOD in some instances. Additional results indicated that instructors were willing to teach using AOD and female students were agreeable to using AOD in their classes.

Computer Proficiency For Online Learning: Factorial Invariance Of Scores Among Teachers, Amy L. Martin, Todd D. Reeves, Thomas J. Smith, David A. Walker

Mid-Western Educational Researcher

Online learning is variously employed in K-12 education, including for teacher professional development. However, the use of computer-based technologies for learning purposes assumes learner computer proficiency, making this construct an important domain of procedural knowledge in formal and informal online learning contexts. Addressing this concern, this study examined the score properties and invariance (N=11,709) of an eight-item self-report measure of computer proficiency for online learning, the CPOL. Results from a confirmatory factor analysis suggest that the hypothesized unidimensional structure undergirded the instrument’s scores, and invariance analyses suggested that the instrument functions similarly across teacher populations defined by gender, grade level …

Lesson Plan: An Agenda For Change In American Higher Education, George S. Mcclellan

Mid-Western Educational Researcher

Book Review

Current Status Of Stem Cell Therapy: Opportunities And Limitations, Elena Rusu, Laura Georgiana Necula, Ana Iulia Neagu, Mihail Alecu, Cristian Stan, Radu Albulescu, Cristiana Pistol Tanase

Turkish Journal of Biology

Over recent years stem cells have stood out as a promising tool for regenerative medicine, providing alternative therapeutic solutions for a large number of diseases. Many clinical trials using stem cells or induced pluripotent stem cells are focused on the repair and regeneration of various tissues and organs in degenerative diseases, whose current treatment only succeeds in slowing down the progression of the disease. Although the preliminary results are interesting, further studies are required in order to evaluate the safety and benefits of stem cell therapy, considering the teratoma development and ethical considerations in embryonic stem cell cases or reprogramming-induced …

The Heart Of The Matter: Cardiac Stem Cells, Esra Çağavi̇, Arzuhan Koç, Sevi̇lay Şahoğlu Göktaş

Turkish Journal of Biology

Cardiovascular diseases are the primary cause of death in the world. Pharmacological and surgical approaches are the main treatment options for heart disease; however, heart transplantation may be the only option for advanced heart failure patients despite its limited nature. Recent advances enabled stem cell-based therapies to become a promising treatment approach for injured or weakened cardiac tissue. With the identification of resident and heart-specific stem cells in early 2000, new avenues of research have been opened to understand heart development, disease, and regeneration. In this review article, different cardiac stem cell subpopulations are classified and defined based on the …

Glioblastoma Stem Cells: A Therapeutic Challenge, Erdoğan Pekcan Erkan, Ufuk Vurgun, Reşat Serhat Erbayraktar, Zübeyde Erbayraktar

Turkish Journal of Biology

The outcome for glioblastoma patients remains extremely poor, despite the advances in surgical and medical fields. It is hypothesized that glioblastoma progression, as well as tumor recurrence, is driven by a small number of cells called cancer stem cells (CSCs), which are characterized by their ability of self-renewal and proliferation, giving rise to progeny of transformation into multiple neuroepithelial lineages. Understanding the biology of CSCs is likely to explain why existing treatment strategies fail to affect the relatively quiescent and resistant CSC compartment. Here, we review the current knowledge on CSCs in glial tumors. In addition, we discuss the importance …

Induced Pluripotent Stem Cells: Methods, Disease Modeling, And Microenvironment For Drug Discovery And Screening, Suresh Palamadai Krishnan

Turkish Journal of Biology

The raging ethical, religious, moral, political, and safety issues pertaining to the use of embryonic stem cells for therapy and research have prompted researchers to develop possibly better alternatives that are more efficacious and serve multiple purposes. Induced pluripotent stem cells (iPSCs) developed by multiple methods provide an unparalleled source of cells that could be differentiated into progeny cells. In cell-based disease models the progeny cells mimic, at least in part, the pathology of the studied disease and are used to improve the mechanistic understanding of the pathology. Furthermore, these cells could be used to test the efficacy and safety …

Cancer Stem Cells: Lessons Learned From The Leukemic Stem Cells, Ayten Kandi̇lci̇

Turkish Journal of Biology

Cancer is the second cause of death in Turkey and the frequency of cancer deaths increased from 12% in 2002 to 21% in 2009 ( Özkan et al., 2013). To win the war on cancer, we certainly need to apply well-planned prevention policies, given that it is caused mostly by environmental factors, and to develop more effective therapies. To achieve a cure for the disease, it is crucial to understand the cellular and molecular mechanisms leading to cancer and to therapeutically target all the factors playing a role in the initiation, progression, maintenance, and relapse of the disease, preferably in …

Epigenetics: The Guardian Of Pluripotency And Differentiation, Marta Gladych, Aleksandra Nijak, Paula Lota, Urszula Oleksiewicz

Turkish Journal of Biology

Multicellular organisms comprise a variety of cell types that have the same genotype but distinct phenotypes. This diversity is possible because of the establishment of a specific epigenetic landscape that stabilizes gene expression profiles that are exclusive for a particular cell type. Accumulating data indicate that the maintenance, loss, and reacquisition of pluripotency are dynamically regulated by epigenetic alterations evoked by a subset of cellular factors. A better understanding of the epigenetic mechanisms involved in stem cell biology and differentiation will improve our ability to use these cells in the clinical context. Here we review current insights into the epigenetic …

Epigenetic Regulation Of Specific Transcription Factors In Osteogenicdifferentiation Of Mesenchymal Stem Cells, Milad Zadi Heydarabad, Mousa Vatanmakanian, Mina Nikasa, Majid Farshdousti Hagh

Turkish Journal of Biology

An abundance of experiments have been performed to clarify the differentiation process of mesenchymal stem cells (MSCs). Osteogenic differentiation and in vitro conditions favoring these cell lineages have attracted the attention of many researchers. Moreover, the gene expression profile during MSC differentiation toward its main specialized cells (bone, cartilage, and adipose cells) has been mostly understood. In the last decades another layer of investigation has attempted to clarify the epigenetic mechanisms underlying MSC differentiation into its specialized cells. It has been shown that as MSCs progress through the differentiation process, more nonspecific genes undergo DNA methylation to prevent differentiation into …

Human Embryonic Stem Cell N-Glycan Features Relevant To Pluripotency, Sabi̇re Karaçali

Turkish Journal of Biology

Human embryonic stem cells (hESCs) and reprogrammed human induced pluripotent stem cells (hiPSCs) proliferate indefinitely in the undifferentiated state (self-renewal) and differentiate into the three germ layers (and ultimately into all cell types) (pluripotency). Branching in the N-glycan core of hESCs/hiPSCs is limited. hESCs/hiPSCs have high mannose-type and biantennary complex-type core structures, indicating immature stages of N-glycoproteins. The two branches on the core consist of type 2 N-acetyllactosamine (LacNAc), completed mainly with α 2,6-linked sialic acid. Complex terminal fucosylation, particularly α 1,2-linked fucosylation, is another characteristic N-glycosylation feature of hESCs/hiPSCs. All of these structural features are probably associated with the …

Limbal Stem Cell Deficiency: Special Focus On Tracking Limbal Stem Cells, Santhosh Kacham, Bhaskar Birru, Sreenivasa Rao Parcha, Ramaraju Baadhe

Turkish Journal of Biology

The cornea, the transparent part of the eye that helps in the formation of images, has multiple layers. Among them, the superficial epithelial layer is protected and maintained homeostatically by the limbus, located in the periphery of the cornea. Limbal stem cells are located at the basal layer of the limbus and the loss of these cells is called limbal stem cell deficiency (LSCD). LSCD is characterized by corneal vascularization, inflammation, and conjunctivalization, which ultimately lead to blindness. Several clinical transplantation procedures used for the treatment of LSCD are cultivated limbal epithelial transplantation, simple limbal epithelial transplantation, and cultured oral …

Comparison Of The Osteogenic Differentiation Capacity Of Adipose Tissuederived Mesenchymal Stem Cells From Humans And Rats, Seçi̇l Erden Tayhan, Şeyma Taşdemi̇r, Sai̇me İsmet Deli̇loğlu Gürhan, Erol Mi̇r

Turkish Journal of Biology

Mesenchymal stem cells (MSCs) can be found in many types of adult tissues such as the bone marrow, adipose, placenta, liver, and periosteum. Recently, adipose tissue-derived MSCs (ADMSCs) have become one the most preferred MSC types because of their fast proliferation rate, abundance, and high plasticity for variable cell types. It is known that ADMSCs are able to differentiate into various cells, including osteoblasts, so they are quite promising for orthopedic clinical trials. The present study aimed to compare the osteogenic differentiation conditions of MSCs from human adipose tissue (hADMSC) and those of MSCs from rat adipose tissue (rADMSC). Therefore, …

Analysis Of Global Micrornaome Profiles Of Caenorhabditis Elegans Oocytes And Early Embryos, Selen Güçlü Durgun, Ahmet Raşi̇t Öztürk, Arzu Atalay

Turkish Journal of Biology

One of the most complex cell transformations in biology is the remodeling of a fertilized oocyte into a totipotent zygote. There is no transcription during this event, and therefore mRNAs and proteins accumulated in the oocyte during oogenesis are utilized until zygotic genome activation. In order to differentiate into somatic cells, the embryo must erase the totipotency signature coming from the oocyte cytoplasm in the somatic blastomeres. In this study, the microRNAome profiles of oocytes and early embryos before and after zygotic genome activation were identified. By using next-generation high-throughput pyrosequencing and miRNA microarray techniques, miRNAome profiles of Caenorhabditis elegans …

Human Adipose-Derived Stem Cells Differentiation Into Epidermal Cells And Interaction With Human Keratinocytes In Coculture, Alexandra Gaspar, Daniel Constantin, Ana-Maria Seciu, Lucia Moldovan, Oana Craciunescu, Elena Ganea

Turkish Journal of Biology

Current procedures used for skin injury reepithelization have yet to improve. At present, stem cell-based therapies provide great potential in repairing different damaged tissues due to the multipotent character of these cells. This study aimed to investigate the in vitro differentiation capacity of human adipose-derived stem cells (ASCs) into epidermal cells and to evaluate their interaction with HaCaT keratinocytes in coculture experimental models that mimicked the living environment of human skin. The mesenchymal phenotype of isolated stem cells was indicated by their spindle-shaped morphology and the expression of specific surface markers CD73, CD90, and CD105. After 21 days of cultivation …

Baculoviral Vector Loaded Mesenchymal Stem Cells As Efficient Gene Therapy Tools For Cancer Treatment, Sedef Hande Aktaş, Hakan Akbulut, Ayşe Eser Elçi̇n, Mahmut Parmaksiz, Arzu Keski̇n Aktan, Arzu Çöleri̇ Ci̇han, Yaşar Murat Elçi̇n, Fi̇kri̇ İçli̇

Turkish Journal of Biology

Insufficient targeting of the therapeutic genes to tumor cells is one of the major reasons for failure in cancer gene therapy. Mesenchymal stem cells (MSCs) seem to be a good candidate as a carrier for gene therapy because of its selective tumor tissue-homing properties. In the current study, we constructed baculoviral vectors (BVs) carrying cytosine deaminase (CD) (BV-CD) or green fluorescence protein (GFP) genes (BV-GFP) and tested the transduction efficiency of the vectors in tumor and mesenchymal stem cells. We also tested the in vivo efficacy of the BV-CD vector in a colon cancer model. Our results showed that the …

Investigating Corporate Social Responsibility Disclosure By Banks From Institutional Theory Perspective, Wafaa Salah, Iman Mohamed Arafa

Business Administration

Previous research on Corporate Social Responsibility (CSR) has mainly focused on the companies operating in different industry 􀏐ields. Yet, a limited number of research has investigated the CSR practices at the banking sector. Accordingly, this study attempts to add further knowledge to this domain by measuring and comparing the extent and quality of CSR practices and its components which are: Employees, Community, Environment and Corporate governance at a larger geographical scale. Moreover, the relationship between institutional environment and the CSR and its components will be empirically examined. Secondary data provided by CSRHUB database is used for a sample of 231 …

A Quantitative Analysis For The Correlation Between Corporate Financial And Social Performance, Wafaa Salah, Mostafa Salama

Business Administration

Recently, corporate social performance (CSP) is not less important than corporate financial performance (CFP). Debate still exists about the nature of the relationship between the CSP and CFP, whether it is a positive, negative, or a neutral correlation. The objective of this study is to explore the relationship between corporate social responsibility (CSR) reports and CFP. The study uses the accounting-based and market-based quantitative measures to quantify the financial performance of seven organizations listed on the Egyptian Stock Exchange in 2007-2014. Then uses the information retrieval technologies to quantify the contribution of each of the three dimensions of the corporate …

Coordination Of Monetary And Fiscal Policies: The Case Of Egypt, Sahar M. Abdel-Haleim

Business Administration

Coordination is defined as the necessary arrangements that assure that the decisions taken by monetary and fiscal authorities are not contradictory. The need for effective coordination of policies becomes pressing with the increasing independence of both authorities to implement their objectives. The purpose of the paper is to investigate the extent of coordination between monetary and fiscal policies in Egypt over the period (1974-2015). Quantifying the extent of coordination depends on the appropriate policy mix that responds effectively to different shocks. The results confirm that coordination of policies was absent or weak during most of the period under study, while …

Determinants Of Fdi Flows To Developing Countries: An Empirical Study On The Mena Region, Dalia Ahmed Elmosalamy, Sherif M. Abbas

Business Administration

Many studies have provided evidence that foreign direct investment (hereafter FDI) can convey great advantages to host countries and can have important positive effects on their development efforts and economic growth. This paper contributes to the extant literature by providing evidence on the main determinants of FDI inflows and exploring the hindering factors that may have a negative influence on FDI and consequently economic growth. Our focus is the Middle East and North Africa (MENA) region over the period 2006 to 2013, a period of great economic and political turbulence and uncertainty. To conduct this study, regression with time series …

Composite Model Representation For Computer Aided Design Of Functionally Gradient Materials, Fangquan Wang

Masters Theses

"Functionally Gradient Materials (FGMs) feature smooth transition from one material to another within a single object. FGMs modeling is considered to be one of the new challenges in Computer Aided Design (CAD) area. To overcome this challenge, this thesis presents a composite approach to model FGMs. The input in STL format can be meshed and voxelized in FGMs modeling system. The material composition in each voxel can be generated from multiple different types of control features. And LTI filters including Gaussian Filter and Average Filter are applied to blur default material features in order to generate FGMs inside models. The …

Effect Of Timing And Source Of Online Product Recommendations: An Eye-Tracking Study, Qing Zeng

Masters Theses

"Online retail business has become an emerging market for almost all business owners. Online recommender systems provide better services to the consumers as well as assist consumers with their decision making processes. In this study, a controlled lab experiment was conducted to assess the effect of recommendation timing (early, mid, and late) and recommendation source (expert reviews vs. consumer reviews) on e-commerce users' interest and attention. Eye-tracking data was extracted from the experiment and analyzed. The results suggest that users show more interest in recommendation based on consumer reviews than recommendation based on expert reviews. Earlier recommendations do not receive …

Bridging The Gap Between Supply Chain And Consumer Experience, Cui Zou

Masters Theses

Many researchers agree that supply chain management is at the root of addressing customer values and increasing customer satisfaction. However, in reality the route to accomplishing these goals is not so clearly defined. The studies herein attempt to shed some insight on a special perspective to bridge the gap between supply chain and customer experience. The ideas behind these studies explore the notion that customer experience can be impacted by a vast spectrum of factors from suppliers to even the specific mobile commerce (m-commerce) tools they use.

To gain insight into the supplier dimension of the supply chain, a survey …

Using Eye-Tracking To Understand User Behavior In Deception Detection System Interaction, Prashanth Kumar Lakkapragada

Masters Theses

"This research presents the analysis of data collected using eye-tracking devices on user interaction with a deception detection system. The differences between two groups of subjects, namely Innocent and Guilty, were compared, where Innocent subjects did not carry any explosive and hence, had nothing to hide in declaring objects that they were carrying whereas Guilty subjects had to lie to deceive the system. The results indicate that there is no significant difference in pupil dilation between the Innocent and Guilty subjects. However, the amount of fixations on the empty spaces of slides containing an explosive image can be used to …

Mechanistic Understanding Of Water-Rock Interactions During High-Salinity Water-Flooding Of Carbonate Reservoirs, Pu Han

Masters Theses

"Chemically tuned water-flooding provides a relatively cheap method of enhanced oil recovery from carbonate and sandstone reservoirs. Several possible recovery mechanisms such as mineral dissolution, multi-component ion exchange, double-layer expansion, adsorption/desorption from rock surface, reduction in interfacial tension, and fines migration that have been proposed are widely debated. The combination of these processes may result in wettability alteration that increases sweep efficiency of water-flooding. Here, wettability alteration due to water-rock interactions will be examined numerically.

To evaluate the wettability alteration, separation between breakthrough curves of the non-reactive component and the cations based on the chromatographic separation will be used due …

A Study On Non-Metallic Inclusions In Foundry Steel Process, Marc Leonard Harris

Masters Theses

"The effects of sample area and automated SEM/EDS feature analysis parameters (step size, magnification and threshold) on nonmetallic inclusion characterization results has been investigated and optimized. A post-processing program was developed to automatically determine average inclusion chemistry, total element concentrations within inclusions, and for generating joint ternary diagrams with size visualization for representing nonmetallic inclusion populations. Using these tools the evolution of nonmetallic inclusions was examined for 4320 steel at a participating industrial steel foundry. The steel was sampled throughout electric arc furnace melting through ladle refining to the final casting where an in-mold sampling procedure was developed to procure …

El Matrimonio, ¿Todavía Importa?: Una Evaluación De La Convivencia A La Luz De La Biblia, Richard M. Davidson

Faculty Publications

No abstract provided.