Digital Commons Network^™

Adaptive Control Architectures For Mitigating Sensor Attacks In Cyber-Physical Systems, Tansel Yucelen, Wassim M. Haddad, Eric M. Feron

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The accuracy of sensor measurements is critical to the design of high-performance control systems since sensor uncertainties can significantly deteriorate achievable closed-loop dynamical system performance. Sensor uncertainty can arise due to low sensor quality, sensor failure, or detrimental environmental conditions. For example, relatively cheap sensor suites are used for low-cost, small-scale unmanned vehicle applications that can result in inaccurate sensor measurements. Alternatively, sensor measurements can also be corrupted by malicious attacks if dynamical systems are controlled through large-scale, multilayered communication networks as is the case in cyber-physical systems. This paper presents several adaptive control architectures for stabilization of linear dynamical …

Comparative Analysis Of Long-Lived Free Radicals In Medical Grade Ultra High Molecular Weight Polyethylene (Uhmwpe) In Absence And Presence Of Vitamin E, Afsana Sharmin

Electronic Theses and Dissertations Archive

In this research, free radical analyses were performed using electron spin resonance (ESR) technique for two groups of orthopedic ultra-high molecular weight polyethylene (UHMWPE). In the first group, Group A, two UHMWPE resins, GUR 4150 and Hylamer (Himont 1900) were investigated. These materials were provided by the Medical-Device Industry members of the NSF-Industry/University Center for Biosurfaces (IUCB), a partnership program between the State University of New York at Buffalo (SUNY Buffalo) and the University of Memphis (1997-2011). The present study is a part of the ongoing research project which was undertaken in 1998. The long-term effects of temperature (23°C, 37°C …

On The Exhangeable Negative Multinomial Distribution And Applications To Analysis Of Rna-Seq. Data, Akwasi Opoku Kusi-Appiah

Electronic Theses and Dissertations Archive

This dissertation addresses two types of problems in Applied Statistics. The first deals with the development of a procedure for estimating the correlation structure of RNA-Seq. data and the second type involves introducing a model that can be used to estimate significance of Genesets based on count data such as RNA-Seq. The approach we adopt is to model the RNA-Seq. data by exchangeable negative multinomial distribution. In the first Chapter, we give an overview of the structure of the dissertation, introduce some definition and also introduce the Exchangeable NegativeMultinomial Distribution resulting from relaxing the independence of the Multinomial distribution to …

Global Financial Crisis And Challenges : Discussion = 全球金融危機與挑戰 : 討論, Tak Hing, Erebus Wong

South South Forum 南南論壇

On 27th July 2016, at SSFS 3, Erebus Wong gave a presentation titled "More Science or Ethnics in Economics and Finance?".

Cephalopods Are Best Candidates For Invertebrate Consciousness, Jennifer A. Mather, Claudio Carere

Animal Sentience

Insects might have been the first invertebrates to evolve sentience, but cephalopods were the first invertebrates to gain scientific recognition for it.

Place-Based Learning: Instilling A Sense Of Wonder., Jeanne L. Surface

Rural Futures Institute: Publications

Place-based learning is powerful. It can be implemented in rural, suburban and urban school districts as well as universities. Contextualizing learning with the students lived experiences will increase student achievement and in the words of Rachel Carson, create “a sense of wonder so indestructible that it would last throughout life (2011).”

Contra Hegemony : Part 2 : Post Capital Business Planning And Its Global Market Potencies = 逆反霸權 (2) : 後資本主義商業計劃及其全球市場潛力, Eka Swadiansa

South South Forum 南南論壇

On 27th July 2016, at the Third South South Forum on Sustainability, Eka Swadiansa delivered the second part of his presentation on Contra Hegemony. The title of this session is Contra Hegemony (Part 2): Post Capital Business Planning and its Global Market Potencies.

Land Cover Data For The Mississippi-Alabama Barrier Islands, 2010-2011 Arcgis V10.3 Geodatabase, Gregory A. Carter, Carlton P. Anderson, Kelly L. Lucas, Nathan L. Hopper

Land Cover Data for the Mississippi-Alabama Barrier Islands, 2010-2011

Land cover on the Mississippi-Alabama barrier islands was surveyed in 2010-2011 as part of continuing research on island geomorphic and vegetation dynamics following the 2005 impact of Hurricane Katrina. Results of the survey include sub-meter GPS location, a listing of dominant vegetation species and field photographs recorded at 375 sampling locations distributed among Cat, West Ship, East Ship, Horn, Sand, Petit Bois and West Dauphin Islands. The survey was conducted in a period of intensive remote sensing data acquisition over the northern Gulf of Mexico by federal, state and commercial organizations in response to the 2010 Macondo Well (Deepwater Horizon) …

Cdx4 Coordinates Mesoderm Specification, Segmentation And Morphogenesis, Saptaparni Bandyopadhyay

Open Access Dissertations

Cdx4 is a ParaHox family of transcription factor that regulates Hox gene function in patterning and imparts identity to different segments of the body of a vertebrate organism. Somitogenesis, is the periodic and sequential division of the paraxial mesoderm of a vertebrate organism into repetitive segments called somites, which are the precursors of the muscle, dermis and vertebrae. Somite formation is an outcome of strictly orchestrated programs that bring together aspects of growth, fate specification, movement and differentiation of the trunk-tail paraxial mesodermal tissue. Although extensive studies have been carried out to understand the function of Cdx4 in patterning, its …

Volume 53, Number 50: July 27, 2016, University Of North Dakota

University Letter Archive

No abstract provided.

Transgenerational Effects Of Thermal Stress: Impacts On And Beyond Coral Reproduction, Alyson Kuba

HCNSO Student Theses and Dissertations

Ocean warming causes stress to corals and records reveal that periods of thermal stress are increasing in frequency and severity. Previous studies show that thermal stress negatively impacts the reproductive output of corals. However, the transgenerational impacts of coral bleaching have never been quantified. As a consequence, it is unclear how ocean warming may alter population dynamics due to effects on reproduction and recruitment. This study quantified the transgenerational impacts of thermal stress in Montastraea cavernosa. To assess transgenerational effects of temperature stress during gametogenesis, colonies were exposed to elevated temperature for two weeks four months prior to spawning, …

Variation In Leaf Wettability Traits Along A Tropical Montane Elevation Gradient, Gregory R. Goldsmith, Lisa Patrick Bentley, Alexander Shenkin, Norma Salinas, Benjamin Blonder, Roberta E. Martin, Rosa Castro-Ccossco, Percy Chambi-Porroa, Sandra Diaz, Brian J. Enquist, Gregory P. Asner, Yadvinder Malhi

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

• Leaf wetting is often considered to have negative effects on plant function, such that wet environments may select for leaves with certain leaf surface, morphological, and architectural traits that reduce leaf wettability. However, there is growing recognition that leaf wetting can have positive effects.
• We measured variation in two traits, leaf drip tips and leaf water repellency, in a series of nine tropical forest communities occurring along a 3300-m elevation gradient in southern Peru. To extend this climatic gradient, we also assembled published leaf water repellency values from 17 additional sites. We then tested hypotheses for how these traits should …

Three Distinct Glutamate Decarboxylase Genes In Vertebrates, Brian P. Grone, Karen P. Maruska

Faculty Publications

Gamma-aminobutyric acid (GABA) is a widely conserved signaling molecule that in animals has been adapted as a neurotransmitter. GABA is synthesized from the amino acid glutamate by the action of glutamate decarboxylases (GADs). Two vertebrate genes, GAD1 and GAD2, encode distinct GAD proteins: GAD67 and GAD65, respectively. We have identified a third vertebrate GAD gene, GAD3. This gene is conserved in fishes as well as tetrapods. We analyzed protein sequence, gene structure, synteny, and phylogenetics to identify GAD3 as a homolog of GAD1 and GAD2. Interestingly, we found that GAD3 was lost in the hominid lineage. Because of the importance …

Third-Party Reproductive Practices: Legislative Inertia And The Need For Nuanced Empirical Data, Susan Markens

Publications and Research

In their article, ‘Gamete donor anonymity and limits on numbers of offspring: the views of three stakeholders’, Margaret K. Nelson, Rosanna Hertz and Wendy Kramer draw on survey data from gamete donors, parents who used gametes to conceive, and donor-conceived offspring in order to understand the position that various stakeholders are likely to hold regarding the regulation of two issues pertaining to gamete donation: anonymity and limits on numbers of offspring.1 This commentary elaborates on the politics underlying conflicts and agreements among various stakeholders involved with third-party reproduction and details the need for data to better inform legislation regarding assisted …

Cytojournal Quiz Cases: Publishing Open-Access, Pubmed-Searchable Cytopathology Cases With Educational Messages, Katherine G. Akers, Vinod B. Shidham

Library Scholarly Publications

No abstract provided.

Soaring, Eric F. Spina

President's Blog: From the Heart

I’m an aerospace engineer, so it was, admittedly, a thrill last weekend to visit the U.S. Air Force Museum. It’s a local treasure right in our backyard that’s devoted to preserving and telling the story of aerospace technology through the ages. (Not to mention the fact that it all began with our friends, the Wright brothers, just next door!)

Mechanisms Of Progranulin Action And Regulation In Genitourinary Cancers., Ryuta Tanimoto, Kuojung G Lu, Shi-Qiong Xu, Simone Buraschi, Antonino Belfiore, Renato V. Iozzo, Andrea Morrione

Department of Urology Faculty Papers

The growth factor progranulin has emerged in recent years as a critical regulator of transformation in several cancer models, including breast cancer, glioblastomas, leukemias, and hepatocellular carcinomas. Several laboratories, including ours, have also demonstrated an important role of progranulin in several genitourinary cancers, including ovarian, endometrial, cervical, prostate, and bladder tumors, where progranulin acts as an autocrine growth factor thereby modulating motility and invasion of transformed cells. In this review, we will focus on the mechanisms of action and regulation of progranulin signaling in genitourinary cancers with a special emphasis on prostate and bladder tumors.

Alginate Hydrogels As Three-Dimensional Scaffolds For In Vitro Culture Models Of Growth Plate Cartilage Development And Porcine Embryo Elongation, Taylor D. Laughlin

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

The establishment of in vitro culture models utilizes tissue engineering principles to design functional mimics of in vivo environments in vitro. Advantages for the use of in vitro culture models include ethical alleviation of animal models for therapeutic testing, cost efficiency, and a greater ability to study specific mechanisms via a systematic, ground-up approach to development. In this thesis, alginate hydrogels are utilized in the development of in vitro culture models of porcine embryo elongation and growth plate cartilage development. First, the effect of scaffold and modifications to the scaffold were explored in both projects. In order to modulate …

Odorant Receptors Can Mediate Axonal Identity And Gene Choice Via Campindependent Mechanisms, Kiavash Movahedi, Xavier Grosmaitre, Paul Feinstein

Publications and Research

Odorant receptors (ORs) control several aspects of cell fate in olfactory sensory neurons (OSNs), including singular gene choice and axonal identity. The mechanisms of OR-induced axon guidance have been suggested to principally rely on G-protein signalling. Here, we report that for a subset of OSNs, deleting G proteins or altering their levels of signalling does not affect axonal identity. Signalling-deficient ORs or surrogate receptors that are unable to couple to Gs/Golf still provide axons with distinct identities and the anterior–posterior targeting of axons does not correlate with the levels of cAMP produced by genetic modifications. In addition, we refine the …

Ocean Acidification Affects Fish Spawning But Not Paternity At Co2 Seeps, Marco Milazzo, Carlo Cattano, Suzanne H. Alonzo, Andrew Foggo, Michele Gristina, Riccardo Rodolfo-Metalpa, Mauro Sinopoli, Davide Spatafora, Kelly A. Stiver, Jason M. Hall-Spencer

School of Biological and Marine Sciences

No abstract provided.

Time And Nationhood: The United States And Indigenous Nations, Frederick W. Tillman Ii

Master of Arts in American Studies Capstones

This study examines the temporal rhetoric and discourse in documents of the Indian Removal debate of the late 1820s and early 1830s. The national narratives of both the United States and Cherokee nation are found to be inherently temporal. This study analyzes four key documents of the Removal debate in the form of memorials, speeches before congress, addresses to the people of the United States, and court cases.Time is found not only to help build nations in the minds of its members, but in the case of the United States, it is also found to help maintain the colonial-nation-state and …

The Effects Of Δ9-Tetrahydrocannabinol (Thc) On Development And Hyperekplexia In Embryonic Zebrafish Model, Olivia Christine Mistretta

Master of Science in Integrative Biology Theses

Marijuana is one of the most commonly used illicit drugs around the world. It has gained attention as an alternative medicine to many different disorders. Though initially investigated in modern medicine for its analgesic and antiemetic properties, cannabis has been recently found to benefit numerous neurological disorders. Though there are over 100 different cannabinoids produced by the cannabis plant, Δ⁹ – tetrahydrocannabinol (THC) has been shown to the most efficacious phytocannabinoid in neurological disorders. THC has been shown in numerous previous studies to be effective at treating spasticity caused by multiple sclerosis and spinal cord injury, as well as …

Geometry Of Holocene Tidal Notches – Sea Level Markers At Perachora Peninsula, Gulf Of Corinth, Greece, S Schneiderwind, M Kázmér, S Boulton, I Papanikolaou, K Reicherter

School of Geography, Earth and Environmental Sciences

Tidal notches are a generally accepted sea level indicator that, when different from mean sea level, witness tectonic activity at or near coastlines. However, how to infer related information is controversial since tectonic uplift from a single seismic event is not likely to exceed several decimetres. High resolution laser scanning offers the availability of close-up views on exposures and to detect evidence for multiple sea level indicators in between major emergence. Statistically representative profiles along exposure were analysed in order to prove for already described tidal notches and to highlight similar shapes in consistent geometries along coastal cliffs of Perachora …

Integrated Transcriptomic And Proteomic Analyses Of P. Falciparum Gametocytes: Molecular Insight Into Sex-Specific Processes And Translational Repression., E Lasonder, Sr Rijpma, Bc Van Schaijk, Wa Hoeijmakers, Et Al

School of Biomedical Sciences

Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease. The molecular processes orchestrating these transitions are far from fully understood. Here, we report the first transcriptome analysis of male and female Plasmodium falciparum gametocytes coupled with a comprehensive proteome analysis. In male gametocytes there is an enrichment of proteins involved in the formation of flagellated gametes; proteins involved in DNA replication, chromatin organization and axoneme formation. On the other hand, female gametocytes are enriched in proteins required for zygote formation and functions after fertilization; …

Caterpillars, Consciousness And The Origins Of Mind, Arthur S. Reber

Animal Sentience

A novel framework for the origins of consciousness and mind, the Cellular Basis of Consciousness (CBC), is presented. The model is based on a simple, perhaps radical axiom: subjectivity is an inherent feature of particular kinds of organic form. Experiential states, including those denoted as "mind" and "consciousness," are present in the most primitive species. The model has several conceptual and empirical virtues, among them: (a) it (re)solves the problem of how minds are created by brains ─ also known as the "Hard Problem" (Chalmers 1995) ─ by revealing that the apparent difficulty results from a category error, (b) it …

Graemeloweus, A New Scorpion Genus From Northern California, Usa (Scorpiones: Vaejovidae), Michael E. Soleglad, Victor Fet, Matthew R. Graham, Richard F. Ayrey

Euscorpius

Genus Graemeloweus, gen. nov. (Scorpiones: Vaejovidae) is described from northern California, USA. The genus is composed of three species formerly placed in Pseudouroctonus: Graemeloweus iviei (Gertsch et Soleglad, 1972), comb. nov. (type species), G. glimmei (Hjelle, 1972), comb. nov., and G. maidu (Savary et Bryson, 2016), comb. nov. Major diagnostic characters of Graemeloweus include a non-bifurcated primary lamellar hook, the presence of a secondary lamellar hook, a complex mating plug with a two part base and an asymmetric crescent-shape barb, and the presence of a well-developed ventromedian (V2) carina on the pedipalp chela. Evidence is presented suggesting that …

Novel Hormonal Combination Therapy For Triple Negative Breast Cancer, Ankita Thakkar

Open Access Dissertations

Anti-estrogen and anti-HER2 treatments have been among the first and most successful examples of targeted-therapy for breast cancers. However, around 10-20% of breast cancers lack estrogen receptor (ER) expression and HER2 amplification. Therefore, the treatment of ER-/HER2- Triple Negative Breast Cancer (TNBC) remains a major challenge due to lack of a druggable target. Currently, TNBCs are treated with non-targeted conventional chemotherapy and although they respond initially, less than 30% patients survive beyond 5 years highlighting the need for novel therapeutic strategies for this disease. We previously discovered that approximately two-thirds of TNBCs express Vitamin D Receptor (VDR) and/or Androgen Receptor …

A Video-Tracking Method To Identify And Understand Circadian Patterns In Drosophila Grooming, Chiyuan Li

Open Access Dissertations

Grooming is nearly universal in terrestrial animals and is important for animals to maintain body surface condition. In insects, grooming is controlled by relatively simple nervous system, so the study of grooming may reveal basic principles of grooming. While recent progress is being made on understanding the mechanism of stimulated grooming control in Drosophila, the internal regulation of non-stimulated grooming remains unexplored. It is possible that the circadian clock plays an important role in the internal regulation of grooming. However, a key problem in the study of grooming’s circadian control is the difficulty of obtaining and interpreting long-term grooming data. …

Cell Therapy Must Be Regulated As Medicine, Zihai Li, Delong Liu

NYMC Faculty Publications

Background

The current standard of care for relapsed and refractory acute lymphoblastic leukemia (ALL) is combination chemotherapy.

Case presentation

We report a case of highly refractory ALL who was treated with blinatumomab. The ALL in this patient relapsed within a month after completion of hyperCVAD regimen and was refractory to high dose mitoxantrone/cytarabine and CLAG regimens.

Conclusion This highly refractory pre-B Ph− ALL was induced to complete remission after one course of single agent blinatumomab.

Weekly News Digest 08/26/2016, Jenna Ray

Weekly Bulletin Archive

News

• Three in Three: Morris Teaching Alumni Are Consecutive ISD 200 Teachers of the Year
• University of Minnesota, Morris Teacher Education Program Nationally Accredited
• VFW Creates Scholarship for Veterans and Families at the University of Minnesota, Morris
• Pete Wyckoff and Timna Wyckoff Awarded Elite Science Policy Fellowships
• Laura Borkenhagen Named UMAC Nominee for NCAA Woman of the Year