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Issues In Laser Induced Breakdown Spectroscopy For Measurements In The Deep Ocean And Other High-Pressure Environments, Joseph C. Bonvallet

Theses and Dissertations

This dissertation describes fundamental and applied studies that have advanced the understanding and application laser induced breakdown spectroscopy (LIBS) to the deep-ocean environment and to operation on a deep-ocean submersible. Chapter one is an overview of LIBS including a brief history, LIBS theory, the instrumentation typically used, and a specific application. Chapter two analyzes the effect that monodisperse suspended particles have on LIBS emission intensity and on the formation of a LIBS plasma. This chapter demonstrates that for particle concentrations similar to those found in the neutrally buoyant regions around hydrothermal vents there is little effect on the LIBS emission …

Special Education Disproportionality Through A Social Lens: A Mixed Methods Approach, Marianne J. Fidishin

Dissertations

The disproportionate nature of special education, notably with African American students, is longstanding and most pronounced in judgmental eligibility categories such as intellectual disability and emotional disturbance. Numerous studies on disproportionality conclude there is not a single causative factor, but point to the multifactorial nature of the issue and the complex interplay among different factors. Research related to the role social factors exhibited in an institution have on special education referral and eligibility determination is more limited. This is important since practices employed during the eligibility process take place within the institution’s social environment and are underpinned by the beliefs …

Understanding Academic Achievement Among Low-Income, Urban, Black Adolescents: The Role Of Father Involvement, Patrick Henry

Master's Theses

Although the Black-White test score gap has improved over time, it still persists. Furthermore, this academic risk for Black youth is compounded by the disproportionate representation of Blacks among low-income families in the U.S. Thus, the present study aims to shed light on factors related to greater academic success among adolescents in low-income, urban, Black families. Overall, this study addresses the following question. How does the presence of a biological father and positive father involvement impact the academic achievement of their adolescent children? Data from the Welfare, Children, and Families: A Three-City Study (TCS) were analyzed in order to address …

Emature: Intergenerational Networks In Digital Media Spaces, Andras Lukacs

Dissertations

While the literature on adolescent usage of the Internet and mobile communication technology is burgeoning, the technological affordance of increased intergenerational contacts and intergenerational friendships received less attention. This project documents how intergenerational virtual networks operate in one particular massively multiplayer online game (World of Warcraft) from the standpoint of adolescent players. Online social worlds are similar to offline settings in a lot of ways. Users must obey certain behavioral standards and follow established rules and moral codes to participate. Despite accounts of online democracy and networked individualism, control and authority is central to the functioning of these environments. Power-relationships …

Development Of "Inside-Out" Pegylated Crosslinked Hemoglobin Polymers: Novel Hemoglobin-Based Oxygen Carriers (Hboc), Kyle Douglas Webster

Dissertations

The development of an effective blood substitute is urgent due to increasingly common blood shortages, the need to type-match donated blood, and communicable diseases (e.g. HIV) posing risks for blood transfusions around the world. There have been many attempts at creating hemoglobin-based oxygen carriers (HBOC) using a variety of techniques centered around the use of polyethylene glycol (PEG) conjugated to hemoglobin (Hb) tetramers. A novel method, “Inside-Out” PEGylation, has been developed by our lab to produce a polyethylene glycol crosslinked hemoglobin (PEG XL-Hb) polymer. This method utilizes a single PEG backbone that is surrounded by multiple proteins, instead of covering …

Cardiac Calcium Atpase Dimerization Measured By Fluorescence Resonance Energy Transfer And Chemical Cross-Linking, Daniel Blackwell

Dissertations

The cardiac sarco/endoplasmic reticulum calcium ATPase (SERCA) establishes the intracellular calcium gradient across the sarcoplasmic reticulum membrane. It has been proposed that SERCA forms homo-oligomers that increase the catalytic rate of calcium transport. We investigated SERCA oligomerization in rabbit left ventricular myocytes using a photoactivatable cross-linker. Western blotting of cross-linked SERCA revealed higher molecular weight species consistent with SERCA oligomerization. Fluorescence resonance energy transfer (FRET) measurements in cells transiently transfected with fluorescently-labeled SERCA2a revealed that SERCA readily forms homo-dimers. These dimers formed in the absence or presence of the SERCA regulatory partner, phospholamban (PLB) and were unaltered by PLB phosphorylation …

Remains To Be Seen: Execution And Embodiment In The Early English Atlantic World, Erin M. Feichtinger

Dissertations

This dissertation explores the development of capitalism in the early English Atlantic World (1580 - 1752) and the manipulation of the legal system to criminalize the laboring body in order to more fully exploit the productive output of labor.

Social Skills In Youth With Spina Bifida: A Longitudinal Multimethod Investigation Of Bio-Neuropsychosocial Predictors, Christina Ehrman Holbein

Dissertations

Objective: Despite research documenting social dysfunction in youth with spina bifida (SB), little is known about the etiology of these social difficulties; most investigations identifying predictors of social deficits have concentrated exclusively on one domain. This longitudinal study examines the relative predictive power of neurocognitive (attention and executive function), family (cohesion and conflict), and health-related (body mass index, condition severity) variables on later social skills in youth with SB.

Methods: 112 youth with SB (T1 mean age = 11.19 years) and their families participated in study visits two years apart. Study variables were assessed by multiple methods (questionnaire, medical chart …

Development Of Folate Directed, Protein Based Photodynamic Therapy Agents, Rojenia Jones

Dissertations

To attack cancer cells in a specific manner, we have developed a folate-targeted, photodynamic therapy (PDT) agent. The folate (FA) and the chlorin e6 (Ce6) photosensitizer were attached to bovine serum albumin (BSA) using carbodiimide chemistry. Since over 50% of cancers overexpress folate receptors, FA-BSA-Ce6 can be taken up by them and is an effective PDT agent. Hela cells exposed to FA-BSA-Ce6 in the dark showed no cytotoxicity. Upon exposure to light, the conjugate was dose (time and concentration) dependent. Concentrations less than or equal to 2 µM were not effective at killing Hela cells but concentrations of at 5 …

You're Kind Of Just Conditioned: Women And Female College Students' Defiance Of Dominant Social Messages In The Development Of Leader Self-Efficacy, Shannon Darracott Howes

Dissertations

Researchers have consistently found that women have lower leader self-efficacy (LSE) than men, despite being equally capable as leaders. This is problematic because LSE is associated with many benefits that support the development and enactment of leadership. Despite the importance of LSE, there is a dearth of research on the construct, particularly in the higher education context. This grounded theory study utilized semi-structured interviews with 12 undergraduate students who identified as females or women to explore how they developed LSE. Findings were related with four core concepts that were woven throughout the various categories of themes that comprised the grounded …

Cognitive And Neural Correlates Of Coping And Resilience In Depression, Catherine Lee

Dissertations

Depression is one of the most prevalent and devastating psychological disorders, often with a chronic or remitting/reoccurring course. The inability to effectively cope with stress and negative life events has been strongly linked to the development and maintenance of depression symptoms; yet, the cognitive and biological processes underlying the complex and multidimensional behavioral construct of coping are not well understood. Using a combination of self-report measures, computerized cognitive tasks, and scalp electroencephalography (EEG) methodologies, the present study investigated associations between specific executive function abilities (i.e., inhibition and set-shifting), underlying neural activity, coping strategy and flexibility, and depression symptoms. Results did …

Community Violence Exposure Among Urban African American Males: Understanding The “Buffering Effect” Of Adaptive Social Support Coping On Psychosocial Outcomes, Cynthia L. Pierre

Dissertations

The current study explored the moderating roles of support coping and support

quality in the predictive relationship between community violence exposure (ECV) and a

variety of psychosocial outcomes. Participants were 119 African American males (9 th –

12 th grade; mean age at baseline = 15.33). Participants completed measures of exposure to

violence, support-seeking coping, quality of support from friends and family, and a range

of psychosocial outcomes, and completed these same measures approximately one year

after baseline. Regression analyses were conducted to examine the relationships between

ECV and psychosocial outcomes, as well as the relationships between support coping and …

Changing Medical Education: Early Efforts To Integrate Women's Health Into Education And Training, Mary Katherine Rojek

Dissertations

This is an historical study about the development of women’s health curricula in medical education across the U.S. between 1983 and 2004, a period of a great deal of innovation. At that time, some physicians, medical educators, policy makers, and government officials became aware that most U.S. medical school curricula did not address women’s health in a comprehensive manner and did not attend to many problems that were the primary causes of mortality and morbidity in women. In addition, medical research and medical education were based on a normative male model. Studies of medical education indicate that medical schools are …

“I Am Because We Are”: A Portrait Of Trans* Postsecondary Educators’ Experiences In Higher Education, Symone L. Simmons

Dissertations

Within higher education, trans* students have become more visible and advocacy for them important. To support these claims, scholars have conducted research and produced literature on trans* college students’ identity development and experiences on campuses. However, the lived experiences of trans* educators working in colleges and universities are missing from the literature, consequently from the minds of scholars, practitioners, and administrators alike. Trans* educators experiences are important because they contribute to shifts in higher education conversations around supporting and affirming trans* people on campus. Trans* educators are mentors, advisors, and role-models, teachers, and advocates, and perhaps knowing their journey and …

The Relation Of Exposure To Community Violence To Self- Efficacy Based On Neighborhood, Family, And School Effects In A Community Sample Of Latino-American Youth, Arie Zakaryan

Dissertations

Community violence is considered a “public health epidemic” in the US. Latino youth and families are a burgeoning population in the United States, and many of whom live in neighborhoods exposed to community violence. Multiple contexts should be assessed identifying developmental assets youth use to adjust positively when exposed to violence. This study examines how different environmental contexts, i.e., home, school, neighborhood and acculturation, influence the relationship between exposure to community violence and self-efficacy for Latino youth. The current study uses an archival dataset of a larger longitudinal study (Project on Human Development in Chicago Neighborhoods). A confirmatory factor analysis …

A Game Industry Beyond Diversity: Systemic Barriers To Participation In South Korea, Florence M. Chee

School of Communication: Faculty Publications and Other Works

Digital gaming has become a prominent part of mainstream culture. However, as one may observe in the public exhibitions of this form of play, the multitude of reasons for participation in the games industry are especially divided along gender lines. This paper is an analysis of themes emerging from the critical ethnographic examination of South Korea’s1 online game culture that, upon closer and iterative analyses, point to additional socioeconomic complications and systemic barriers to women’s equitable participation in the game development and production. Using South Korea’s national context as a point of reference, the findings from this case study offer …

Draft Genome For A Urinary Isolate Of Lactobacillus Crispatus, Travis Kyle Price, Majed Shaheen, Laurynas Kalesinskas, Kema Malki, Evann Elizabeth Hilt, Catherine Putonti, Alan J. Wolfe

Bioinformatics Faculty Publications

While Lactobacillus crispatus contributes to the stability of normal vaginal microbiota, its role in urinary health remains unclear. As part of an on-going attempt to characterize the female urinary microbiota, we report the genome sequence of an L. crispatus strain isolated from a woman displaying no lower urinary tract symptoms.

Clusters Of Alpha Satellite On Human Chromosome 21 Are Dispersed Far Onto The Short Arm And Lack Ancient Layers, William Ziccardi, Chongjian Zhao, Valery Shepelev, Lev Uralsky, Ivan Alexandrov, Tatyana Andreeva, Evgeny Rogaev, Christopher Bun, Emily Miller, Catherine Putonti, Jeffrey Doering

Bioinformatics Faculty Publications

Human alpha satellite (AS) sequence domains that currently function as centromeres are typically flanked by layers of evolutionarily older AS that presumably represent the remnants of earlier primate centromeres. Studies on several human chromosomes reveal that these older AS arrays are arranged in an age gradient, with the oldest arrays farthest from the functional centromere and arrays progressively closer to the centromere being progressively younger. The organization of AS on human chromosome 21 (HC21) has not been well-characterized. We have used newly available HC21 sequence data and an HC21p YAC map to determine the size, organization, and location of the …

Land-Use And Algal Species Influence Bacterial Community Composition And Activity In Streams, Miguel Rojas

Master's Theses

Microbial biofilms can be found on virtually all submerged surfaces in aquatic habitats, including rivers and streams. Biofilms are complex, taxonomically diverse communities of microorganisms (including algae and bacteria) that colonize solid surfaces and support a wide range of metabolic activities. Biofilms are critical components of river and stream ecosystems because they are key drivers of nutrient cycling processes (including nitrogen cycling) and because they serve as an important food source for higher trophic levels. Biofilms in urban streams are subject to a number of anthropogenic stressors, but research on the ecology of urban biofilms and their response to stressors …

The Impact Of Social Class Connectedness, School Belongingness, And Family Cohesion On Lower Class-Identified College Students, Kristen Eileen Adams

Dissertations

This study is one of the first to examine acculturative and enculturative factors as they relate to social class. Much of the extant literature surrounding acculturation and enculturation looks primarily at cultural factors such as race/ethnicity and/or immigration status. Due to the fact that social class is such a salient cultural identity in most individuals' lives and has a bearing on how one views and evaluates themselves in relation to others of differing social classes (Fouad & Brown, 2000), the purpose of this study was to examine the effects of social class connectedness on subjective wellbeing (including positive and negative …

Self-Esteem And Critical Consciousness In The Relation Between Subjective Social Class And Subjective Well-Being Among College Students: Mediation And Moderated Mediation Models, Fatma Aydin

Dissertations

Subjective social class (SSC) and subjective well-being (SWB) are important indicators of mental health, and the scientific literature has indicated significant relationships between these variables. The purpose of this study is to examine the complex mechanisms by which SSC is related to SWB, using a sample of 275 college students. This study first explored whether SSC was indirectly related to SWB through the mediating effect of self-esteem. Three elements of SSC (economic resources, social power, and social prestige) and three elements of SWB (satisfaction with life, negative affect, and positive affect) were investigated. Using process analysis, the results showed that …

Critical Role Of C-Jun N-Terminal Kinase Signaling In Binge Alcohol-Driven Atrial Arrhythmic Remodeling, Jiajie Yan Yan

Dissertations

Holiday Heart Syndrome (HHS) is cardiac arrhythmia induced by binge alcohol consumption, a drinking pattern affects 38 million adults in our society. Atrial fibrillation (AF) is the most frequently diagnosed arrhythmia in HHS and causes significant morbidity and mortality. Despite the intensive prevention effort nationwide, the binge drinking population keeps rising. However, no effective treatment strategies are available for binge drinking induced AF due to the unknown underlying mechanisms. In this thesis, I aim to elucidate the mechanisms of binge alcohol-promoted atrial arrhythmogenicity by using a mouse model of repeated binge alcohol exposure established in the Ai Lab.

The Ai …

In Search Of Environmental Sustainability At The Base Of The Pyramid, Mark Heuer, Nancy E. Landrum

School of Environmental Sustainability: Faculty Publications and Other Works

This paper proposes a revision to Hart and Sharma’s 2004 model for corporate engagement with the base of the pyramid (BoP) by making the BoP community and the natural environment, not the firm, the central focus for engagement. The revised model proposes that core stakeholders must include the BoP community, the poor, weak, and illiterate, as they can benefit most from the community collective action model presented herein to address sustainability in the natural environment. These are the core stakeholders rather than fringe stakeholders, as indicated in the Hart and Sharma model. Our model recognizes the legitimacy of the firm …

Controlling Microbial Safety Challenges Of Meat Using High Voltage Atmospheric Cold Plasma, Lu Han, Dana Ziuzina, Caitlin Marie Heslin, Daniela Boehm, Apurva Patange, David Millan-Sango, Vasilis Valdramidis, Patrick J. Cullen, Paula Bourke

Articles

Atmospheric cold plasma (ACP) is a non-thermal technology, effective against a wide range of pathogenic microorganisms. Inactivation efficacy results from plasma generated reactive species. These may interact with any organic components in a test matrix including the target microorganism, thus food components may exert a protective effect against the antimicrobial mode of action. The effect of an in-package high voltage ACP process applied in conjunction with common meat processing MAP gas compositions as well as bacteria type and meat model media composition have been investigated to determine the applicability of this technology for decontamination of safety challenges associated with meat …

Governance And Reporting In A Complex Global Environment, Claire Richards, Mary Ann Reynolds, Jesse Dillard

All Works

The purpose of this paper is to explore whether there are extant mechanisms that are utilized to meet the challenges of diverse corporate governance needs in modern global society. We adopt the nonlinear lens utilized in complex adaptive systems. The examination is advanced using three examples drawn from published academic research. The three examples selected allow consideration of differing levels of analysis, regions and entity types. Levels of analysis include societal, institutional and firm. Regions include Asia Pacific, United States and international. The governance types are governmental, charitable and corporate. Distinct world views are represented by considering the holistic worldview …

The Scientist, 2016, San Jose State University, College Of Science

The Scientist (College of Science)

No abstract provided.

Total Arsenic And Arsenic Speciation In Indigenous Food Stuffs, Bashdar Sadee

School of Geography, Earth and Environmental Sciences Theses

The properties of an element are highly dependent on its chemical form, it’s called elemental speciation. This study evaluates the arsenic species found in a range of food stuffs together with growing environments and toxicity issues. Total arsenic concentrations in fish tissue and vegetable crops were determined by ICP-MS following microwave-assisted acid digestion using nitric acid/hydrogen peroxide, trypsin and cellulase enzymatic extraction procedures. The extracted arsenic species were then quantified using HPLC-ICP-MS. A dilute nitric acid (1 % (v/v)) digestion procedure was also used to extract arsenic species from rice and the different parts (root, skin, stem, leaf and grain) …

Gender Fraud' Where Do We Go From Here?, Penelope Childs

The Plymouth Law and Criminal Justice Review

This paper outlines work in progress that examines liability for sex offences involving 'gender fraud' and asks how things might be viewed differently from a transnormative perspective. It considers vitiation of consent by active deception as to gender and by non-disclosure of gender history and asks what implications recent case law might have for the transgender community.

Observation Of Diurnal Variations In Mesoscale Eddy Sea-Surface Currents Using Goci Data, Ji-Eun Park, Kyung-Ae Park, David S. Ullman, Peter C. Cornillon, Young-Je Park

Graduate School of Oceanography Faculty Publications

The surface current field of a mesoscale eddy in the East Sea (Sea of Japan) was derived from consecutive Geostationary Ocean Color Imager chlorophyll-a (chl-a) concentration images using the normalized maximum cross-correlation method. The estimated current field of the eddy exhibited anticyclonic structure demonstrated by the objective dynamic thresholds of correlation coefficients. The eddy periphery was defined by fitting an ellipse to subjectively selected points from the frontal map of chl-a concentration data. Radial distribution and hourly variation of the current speed around the eddy were presented. In terms of the magnitude and direction, the estimated …

Metagenomic Investigation Of The Geologically Unique Hellenic Volcanic Arc Reveals A Distinctive Ecosystem With Unexpected Physiology, Anastasis Oulas, Paraskevi N. Polymenakou, Rekha Seshadri, H. James Tripp, Manolis Mandalakis, A. David Paez-Espino, Amrita Pati, Patrick Chain, Paraskevi Nomikou, Steven Carey, Stephanos Kilias, Christos Christakis, Georgios Kotoulas, Antonions Magoulas, Natalia N. Ivanova, Nikos C. Kyrpides

Graduate School of Oceanography Faculty Publications

Hydrothermal vents represent a deep, hot, aphotic biosphere where chemosynthetic primary producers, fuelled by chemicals from Earth's subsurface, form the basis of life. In this study, we examined microbial mats from two distinct volcanic sites within the Hellenic Volcanic Arc (HVA). The HVA is geologically and ecologically unique, with reported emissions of CO₂‐saturated fluids at temperatures up to 220°C and a notable absence of macrofauna. Metagenomic data reveals highly complex prokaryotic communities composed of chemolithoautotrophs, some methanotrophs, and to our surprise, heterotrophs capable of anaerobic degradation of aromatic hydrocarbons. Our data suggest that aromatic hydrocarbons may indeed be …