Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2016

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 27061 - 27090 of 29042

Full-Text Articles in Entire DC Network

Design Of Highly Stable Low-Density Self-Assembled Monolayers Using Thiol-Yne Click Reaction For The Study Of Protein-Surface Interactions, Leila Safazadeh Haghighi Jan 2016

Design Of Highly Stable Low-Density Self-Assembled Monolayers Using Thiol-Yne Click Reaction For The Study Of Protein-Surface Interactions, Leila Safazadeh Haghighi

Theses and Dissertations--Chemical and Materials Engineering

Protein adsorption on solid surfaces is a common yet complicated phenomenon that is not fully understood. Self-assembled monolayers have been utilized in many studies, as well-defined model systems for studying protein-surface interactions in the atomic level. Various strategies, including the use of single component SAMs[1, 2], combinations of long and short alkanethiolates with methyl- and hydroxyl- terminal groups[3, 4], and using mixtures of alkanethiolates with similar chain length and varying terminal functional group [5] have been used to effectively control the surface wettability and determine the effect of surface composition and wettability on protein adsorption. In this dissertation we report …

Go to article

Understanding Dna Condensation By Low Generation (G0/G1) And Zwitterionic G4 Pamam Dendrimers, Min An Jan 2016

Understanding Dna Condensation By Low Generation (G0/G1) And Zwitterionic G4 Pamam Dendrimers, Min An

Theses and Dissertations--Chemistry

Cationic polymers have shown potential as gene delivery vectors due to their ability to condense DNA and protect it from cellular and restriction nucleases. Dendrimers are hyperbranched macromolecules with precisely defined molecular weights and highly symmetric branches stemming from a central core. The nanosize, tunable surface chemistries and ease of surface functionalization has made dendrimers an attractive alternative to conventional linear polymers for DNA delivery applications. The commercially available, cationic dendrimer poly(amidoamine) or PAMAM is the most widely studied dendrimer for use as a gene delivery vector. The aim of this dissertation is to provide an increased understanding of the …

Go to article

Design, Synthesis And Physicochemical Analysis Of Ruthenium(Ii) Polypyridyl Complexes For Application In Phototherapy And Nucleic Acid Sensing, Erin Melissa Wachter Jan 2016

Design, Synthesis And Physicochemical Analysis Of Ruthenium(Ii) Polypyridyl Complexes For Application In Phototherapy And Nucleic Acid Sensing, Erin Melissa Wachter

Theses and Dissertations--Chemistry

Current chemotherapeutics exhibit debilitating side effects as a result of their toxicity to healthy tissues. Reducing these side effects by developing chemotherapeutics with selectivity for cancer cells is an active area of research. Phototherapy is one promising modality for selective treatment, where drug molecules are “turned on” when irradiated with light, reducing damage to healthy tissues by spatially restricting the areas exposed to irradiation. A second approach to improve selectivity is to exploit the differences in cancerous versus healthy cells, such as increased metabolism and/or upregulation of cell surface receptors. Ruthenium(II) polypyridyl complexes are candidates for phototherapy due to their …

Go to article

Towards Catalytic Oxidative Depolymerization Of Lignin, Justin K. Mobley Jan 2016

Towards Catalytic Oxidative Depolymerization Of Lignin, Justin K. Mobley

Theses and Dissertations--Chemistry

Lignin is one of the most abundant and underutilized biopolymers on earth. Primarily composed on three monolignol units (sinapyl, coniferyl, and p-coumaryl alcohol), lignin is formed through a radical pathway resulting in an assortment of linkages, of which the β-O-4 linkage is the most prevalent (up to 60% in some hardwood species). In planta, lignin plays an important role in water transport and in protecting plants from chemical and biological attack. Traditional attempts to depolymerize lignin have focused on the cleavage of β-O-4 linkages via thermal or reductive routes. However these pathways lead to low-value, unstable product mixtures. Moreover, …

Go to article

The Development Of Colorimetric Assays To Determine The Identity And Frequency Of Specific Nucleobases In Dna Oligomers, Elizabeth Marie Thomas Jan 2016

The Development Of Colorimetric Assays To Determine The Identity And Frequency Of Specific Nucleobases In Dna Oligomers, Elizabeth Marie Thomas

Theses and Dissertations--Chemistry

Colorimetric methods combined with color-changing chemical probes are widely used as simple yet effective tools for identifying and quantifying a wide variety of molecules in solution. For nucleic acids (DNA and RNA), perhaps the most commonly used colorimetric probe is potassium permanganate, which can be used to identify single-stranded pyrimidines (thymine and cytosine) in polymers. Unfortunately, permanganate is not an effective probe for identifying purines (adenine and guanine), especially in the presence of the more reactive pyrimidines. Therefore, robust methods for discriminating between the purines remain elusive, thereby creating a barrier toward developing more complex colorimetric applications. In this dissertation, …

Go to article

A Qualitative Exploration Of Masculinity Among Community College Males, Marianne Fontes Jan 2016

A Qualitative Exploration Of Masculinity Among Community College Males, Marianne Fontes

Graduate Research Theses & Dissertations

The purposes of this grounded theory study were to explore how traditional-aged community college males experience masculinity and to examine how they engage with community college support systems. Eleven diverse participants engaged in three interviews each in which they were asked to reflect on their definitions of masculinity as well as their activities on and off campus. Open, axial, and selective coding methods were employed, and a new theory emerged. The new theory suggests that the participants' hesitation to make concrete educational decisions is related to their resistance to manhood. Findings implicate the need to engage faculty in the support …

Go to article

Assessing The Compatibility Of Filth Fly Pesticides With Filth Fly Biological Control Parasitoids Through Toxicological And Behavioral Assays, Edwin R. Burgess Iv Jan 2016

Assessing The Compatibility Of Filth Fly Pesticides With Filth Fly Biological Control Parasitoids Through Toxicological And Behavioral Assays, Edwin R. Burgess Iv

Graduate Research Theses & Dissertations

Filth flies are a significant pest at animal production facilities, leading to economic losses that include reductions in animal weight and milk production. Pesticides and biological control organisms are two important components of Integrated Pest Management (IPM) programs against filth flies. Biological control against filth flies frequently involves augmentative releases of pupal parasitoids. The compatibility of pesticides and the parasitoids Spalangia endius Walker and Urolepis rufipes Ashmead was examined using one of the most common filth flies, the house fly, Musca domestica L. The specific goals were to 1) assess the effects of the active ingredients of several house fly …

Go to article

Automatic Machine Learning-Guided Methods For 3d Synapse Quantification In Confocal Neuron Images, Jonathan William Sanders Jan 2016

Automatic Machine Learning-Guided Methods For 3d Synapse Quantification In Confocal Neuron Images, Jonathan William Sanders

Graduate Research Theses & Dissertations

This thesis explores computational methods for automatically detecting and quantifying synapses in complex 3D neuronal images. The resulting approach is a novel combination of traditional image processing, machine learning algorithms, and multi-channel comparison methods designed to overcome the unique challenges posed by these images. The methods investigated combine the strengths of each of these components in order to produce an overall method that is capable of fully detecting the synapses in large 3D confocal neuron images with minimal interaction. Human annotation of 3D neuron images remains prohibitively difficult and subjective, and computational analysis tools are highly desirable in the expanding …

Go to article

Behavioral And Chemical Ecology Of A Male-Produced Substrate-Borne Pheromone In Urolepis Rufipes, Tyler Wittman Jan 2016

Behavioral And Chemical Ecology Of A Male-Produced Substrate-Borne Pheromone In Urolepis Rufipes, Tyler Wittman

Graduate Research Theses & Dissertations

Use of chemical signals for sexual communication is found in a large proportion of insects. Pheromones may also act as honest signals of the sender's health and resources. Most research has focused on female-produced pheromones used for attracting mates over large distances or on the role pheromones play in species and mate recognition. Little work has been done exploring male produced pheromones, and how pheromones may be involved in mate assessment. Here I show that females of the parasitic wasp Urolepis rufipes discriminate for some aspects of male quality through the male's substrate-borne pheromones. In two-choice trials females spent more …

Go to article

Beyond Adat : Transwomen Boldly And Innovatively Navigating Their Communities In Central Java, Indonesia, Laurence Anthonie Tumpag Jan 2016

Beyond Adat : Transwomen Boldly And Innovatively Navigating Their Communities In Central Java, Indonesia, Laurence Anthonie Tumpag

Graduate Research Theses & Dissertations

The purpose of the following thesis was to investigate how transwomen (otherwise known locally as waria) of Indonesia, navigate their gender identities within their specific locales in central Java. Particularly, I focus how my respondents do this within Yogyakarta, which I define as a cultural hub where local custom and law known as adat predominates and two other field sites located in the periphery of Yogyakarta. Due to the importance of local culture in the general central Javanese region, I hypothesized adat serves to help create space and belonging for my transwomen respondents within each locale. While previous research has …

Go to article

A Bioinformatic Study On The Evolution Of Bamboos And Other Graminoid Poales, William P. Wysocki Jan 2016

A Bioinformatic Study On The Evolution Of Bamboos And Other Graminoid Poales, William P. Wysocki

Graduate Research Theses & Dissertations

For the past decade, next-generation sequencing (NGS) has been used to undertake genomics-scale projects in molecular biology. This method of sequencing involves randomly fragmenting a sample of nucleic acid and randomly generating millions of short reads. The large number of reads moves the assembly and other analyses to be performed by computer algorithms. As well as sequencing full chromosomes, full RNA extracts can be sequenced to determine levels of gene expression and exon boundaries. In this study, NGS is used to examine the evolution of bamboos (Bambusoideae), which are a subfamily of grasses (Poaceae). Bamboos are divided into two main …

Go to article

Analysis And Extension Of A Flexible Stochastic Differential Equation Model To Estimate The Amount Of Nanoconjugates Required To Initiate Remission Of Cancer, Nicholas Joseph Skradski Jan 2016

Analysis And Extension Of A Flexible Stochastic Differential Equation Model To Estimate The Amount Of Nanoconjugates Required To Initiate Remission Of Cancer, Nicholas Joseph Skradski

Graduate Research Theses & Dissertations

This thesis examines a definition of reliability that can be applied to targeted nanoconjugate chemotherapy in cancer and also simulates a stochastic differential equation model to attempt to predict the estimated time until remission when using targeted nanoconjugate chemotherapy utilizing a recursive algorithm to attempt to find the dose of nanoconjugates that will result in remission by an expected time T. Areas of research that can be used to obtain model parameter values are cited and values for the dose of nanoconjugates, given as number of nanoconjugates, are predicted for several different model parameters. The model is then extended to …

Go to article

Do Folivores Deplete Patches? : Foraging Behavior And The Dynamics Of Resource Use In The Costa Rican Mantled Howler (Alouatta Palliata), Jessica Ritsche Jan 2016

Do Folivores Deplete Patches? : Foraging Behavior And The Dynamics Of Resource Use In The Costa Rican Mantled Howler (Alouatta Palliata), Jessica Ritsche

Graduate Research Theses & Dissertations

Two general assumptions have often been made about folivorous primates: first, that feeding competition is low or absent because leaves are a superabundant and evenly dispersed resource, and as a result, that feeding competition does not constrain the size of folivorous groups. However, many folivorous primates maintain smaller group sizes. In this study, I aimed to examine this 'folivore paradox' by testing the hypothesis that mantled howler monkeys (Alouatta palliata) deplete localized patches of young leaves and therefore experience feeding competition. One group of 8 adult individuals was studied July and August 2015 at Piro Research Station in the Osa …

Go to article

Engineering And Chromosomal Integration Of A Functional Butanol Pathway In Escherichia Coli For Butanol Fermentation, Erin Garza Jan 2016

Engineering And Chromosomal Integration Of A Functional Butanol Pathway In Escherichia Coli For Butanol Fermentation, Erin Garza

Graduate Research Theses & Dissertations

A butanol fermentation pathway was engineered in Escherichia coli through cloning and chromosomal integration of the butanol genes (thiL, CA_C2873, hbd, crt, bcd, etfA, etfB, adhe1, adhe2, bdhAB) from Clostridium acetobutylicum ATCC824. Initially, a minimal set of butanol pathway genes (thiL, hbd, crt, bcd, etfAB, adhe2) was transcriptionally fused with a pflBp6 promoter and were integrated into the chromosome of E. coli EG10, a strain lacking endogenous competing fermentation pathways, resulting in strain EG60. Anaerobic fermentations showed that EG60 was able to produce 100 muM butanol, suggesting that the butanol pathway genes were effectively expressed for butanol production. Although the …

Go to article

Early Pliocene Ross Sea Paleoclimate And A New Application Of The Diatom Oxygen Isotope Proxy, Hal W. Hackett Jan 2016

Early Pliocene Ross Sea Paleoclimate And A New Application Of The Diatom Oxygen Isotope Proxy, Hal W. Hackett

Graduate Research Theses & Dissertations

Oxygen isotope measurements (δ¹⁸O) provide valuable insight into climate conditions. These data are advantageous as paleoclimate proxies, but records are sparse in high latitude waters, where calcareous microfossils are poorly preserved in marine sediments. Over glacial timescales, high latitude regions likely have the widest variability in terms of the δ¹⁸O values of marine waters; therefore, the paucity of data in these regions greatly hinders our ability to reconstruct global climatic and environmental change. This research is motivated to investigate Southern Ocean diatoms as a way to begin filling the gap in our knowledge. Diatoms are a cosmopolitan group of siliceous …

Go to article

Cfd And Aero-Acoustic Analysis Of Flush Toilet In Airplanes, Dheeraj Kamthamneni Jan 2016

Cfd And Aero-Acoustic Analysis Of Flush Toilet In Airplanes, Dheeraj Kamthamneni

Graduate Research Theses & Dissertations

With the global expansion of air travel and increase in the fleet size of the aircraft with modern technology, the demand for the reduction of sound levels in the airplane toilet is increasing, as it causes discomfort to the passengers. During the cleansing process by air (vacuum), high level of acoustic noise is produced due to the turbulent vortex flow and boundary layer flow separation in the bowl. This study involves investigation of noise generation in a vacuum toilet during the evacuation of bowl in a flush cycle and to identify means to reduce the noise below a target level. …

Go to article

Characterization And Inhibitor Evaluation Of Ispd And Ispe Enzymes From The Non-Mevalonate Pathway, Brian E. Hartnett Jan 2016

Characterization And Inhibitor Evaluation Of Ispd And Ispe Enzymes From The Non-Mevalonate Pathway, Brian E. Hartnett

Graduate Research Theses & Dissertations

There is an immediate need for new antibiotics. Antimicrobial resistance is rising at an alarming rate. In addition, certain select agents are a risk for bioterrorism that necessitate the discovery of new antibiotics. The methylerythritol phosphate (MEP) pathway is a metabolic pathway that produces the isoprenoid precursors, isopentyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP). Notably, the MEP pathway is present in most bacteria and not mammals, which makes the enzymes of the MEP pathway attractive targets for discovering new anti-infective agents due to reduced chances of off-target interactions leading to side effects. Currently, there are very few known inhibitors of …

Go to article

Characterization Of Potential Anti-Infective Agents Of Burkholderia Pseudomallei Targeting Ispf, Joy Michelle Blain Jan 2016

Characterization Of Potential Anti-Infective Agents Of Burkholderia Pseudomallei Targeting Ispf, Joy Michelle Blain

Graduate Research Theses & Dissertations

There is an urgent need for new anti-infective agents. Pathogenic organisms continue to develop resistance to modern-day antibiotics, while there has been a significant decline in the development of antibiotics over the last 30 years. One particular pathway of interest in the development of new antibiotics is the biosynthesis of isoprenoids. These compounds are essential chemical building blocks in pathogenic organisms such as Plasmodium falciparum, Mycobacterium tuberculosis, and Burkholderia pseudomallei. Notably, there are two distinct pathways in the biosynthesis of isoprenoids called the Mevalonate (MVA) pathway and the 2C-methyl-D-erythritol phosphate (MEP) pathway. The MEP pathway enzymes are attractive targets in …

Go to article

Enhancing The Ethanol Pathway In Escherichia Coli Rm10 For Improved Ethanol Production From Xylose, Ryan Allan Manow Jan 2016

Enhancing The Ethanol Pathway In Escherichia Coli Rm10 For Improved Ethanol Production From Xylose, Ryan Allan Manow

Graduate Research Theses & Dissertations

Due to its capability to ferment biomass-derived pentose and hexose, Escherichia coli is considered a potential biocatalyst for production of bioethanol. Gene deletions and promoter replacements were previously employed to engineer a non-transgenic homoethanol pathway in E. coli [glucose (or 1.2 xylose) => (glycolysis) => 2 pyruvate + 2 NADH => (pyruvate dehydrogenase, aceEF-lpd operon) => 2 acetyl-CoA + 4 NADH => (alcohol dehydrogenase, adhE) => 2 acetaldehyde + 2 NADH => (alcohol dehydrogenase) => 2 ethanol]. The resulting strain, RM10, is able to produce ethanol from xylose and glucose, with a yield greater than 90% theoretical (one mole of …

Go to article

Bystander Action Or Inaction During Bullying : An Investigation Into The Role Of Gender, Empathy, Attitudes Toward Aggression, And Social Support, Trevor Bixler Jan 2016

Bystander Action Or Inaction During Bullying : An Investigation Into The Role Of Gender, Empathy, Attitudes Toward Aggression, And Social Support, Trevor Bixler

Graduate Research Theses & Dissertations

This thesis is constructed to delineate mechanisms that influence bystander behavior in the presence of bullying phenomena. Purpose for this study is derived from the shallow empirical history of differentiation between passive outsiders and intervening defenders, particularly when concerned with student populations within the United States. This study included child participants in grades four and five from the Midwestern region. These participants were administered a series of survey measures, in addition being read aloud a vignette depicting bullying. Role orientation, defender or outsider, were examined as an outcome to be related with the social-cognitive predictor variables of empathy, attitudes toward …

Go to article

Carbon Assimilation Of Oak Seedlings In Response To Canopy Thinning Treatments At The Morton Arboretum In Lisle, Illinois, Usa, Mary Rebecca Moses Jan 2016

Carbon Assimilation Of Oak Seedlings In Response To Canopy Thinning Treatments At The Morton Arboretum In Lisle, Illinois, Usa, Mary Rebecca Moses

Graduate Research Theses & Dissertations

White and bur oak savanna was once the dominant vegetation type in the Midwestern United States prior to European settlement. Within the oak savanna biome were pockets of oak-hickory closed forested sites, usually occurring in mesic areas and on the east side of rivers. Restoration efforts to restore the land back to savanna and closed canopy oak dominated forests are met with varying success. There is a need for understanding canopy openness requirements, and ideal forest floor light levels for successful oak regeneration. The purpose of this study is to determine success of oak seedlings growing under varying canopy treatments. …

Go to article

Developing Geospatial Thinking And The Science Practices Of Investigation And Evalutation With Geographic Information Systems, Kelli Hamilton Jan 2016

Developing Geospatial Thinking And The Science Practices Of Investigation And Evalutation With Geographic Information Systems, Kelli Hamilton

Graduate Research Theses & Dissertations

Geospatial thinking is a subset of spatial thinking, which has been identified by the National Geography Standards as an essential skill for students to gain through geography instruction (Heffron & Downs, 2013). One tool which has been shown to help students develop their geospatial thinking skills is Geographic Information Systems (GIS) (Kim & Bednraz, 2013; Lee & Bednarz, 2009; Patterson, 2007). Much of the research conducted with GIS has been in the context of social studies classrooms. This study examined the use of GIS with seventh grade students in a science classroom. Results of this study indicate that students who …

Go to article

Choosing Sustainability : The Relationship Between Personal Standards And Environment Responsive Behavior, Bridget Denise Stuckey Jan 2016

Choosing Sustainability : The Relationship Between Personal Standards And Environment Responsive Behavior, Bridget Denise Stuckey

Graduate Research Theses & Dissertations

This study investigated Personal Standards as a psychological determinant of Environment Responsive Behavior. This was a quantitative study that used questionnaire data collected from community college students in Northern Illinois. This study was guided by three research questions: What is the relationship between Personal Standards regarding the environment and Environment Responsive Behavior? What is the relationship between utility value, personal affect, and outcome expectancy regarding the environment and Environment Responsive Behavior? Are Environment Responsive Behavior and Personal Standards regarding the environment related to gender, childhood locale, field of study, number of semesters completed in college, age, and ethnicity? The data …

Go to article

Conditions Affecting Biomass Productivity, Lipid Production, And Harvesting Of The Microalga Monoraphidium Sp. Dek19 Grown In Wastewater, Adam Ralph Hage Jan 2016

Conditions Affecting Biomass Productivity, Lipid Production, And Harvesting Of The Microalga Monoraphidium Sp. Dek19 Grown In Wastewater, Adam Ralph Hage

Graduate Research Theses & Dissertations

The objective of this thesis was to investigate the culture conditions necessary to promote high cell densities, lipid productivities, and harvesting yields from the locally endemic microalgae Monoraphidium sp. Dek19 in a wastewater environment. The alga was inoculated in final effluent acquired from a local wastewater treatment facility in DeKalb, Illinois. The alga was cultivated in 1L Erlenmeyer flasks at 10°C, 70 μmol m⁻² s⁻¹ light, 14:10 light:dark cycle. Culture agitation was found to be an important condition for algal growth and nutrient removal. Increased culture turbulence through aeration correlated with improved phycoremediation and biomass production. Cultures in stagnant conditions …

Go to article

Construction Of Porous Silicon Schottky Diode Structure, Anjani Challa Jan 2016

Construction Of Porous Silicon Schottky Diode Structure, Anjani Challa

Graduate Research Theses & Dissertations

The thesis work mainly focuses on the Design, Fabrication & characterization and testing of the device using porous silicon. The two wafers used for this work are the silicon wafer coated with silicon nitride on the both sides. To prepare a mask, a design is drawn using AutoCAD software. The photoresist is coated on the front side of the wafer using spin coating technique and the silicon nitride which is coated on the back side of the wafer is removed by Dry chemical etching process. Windows are opened on the front side of the wafer using positive photoresist technique. Silicon …

Go to article

An Examination Of The Athletic Identity, Identity Foreclosure, And Career Maturity Of Division I Collegiate Student-Athletes In Nonrevenue-Producing Sports, Stacia A. Klasen Jan 2016

An Examination Of The Athletic Identity, Identity Foreclosure, And Career Maturity Of Division I Collegiate Student-Athletes In Nonrevenue-Producing Sports, Stacia A. Klasen

Graduate Research Theses & Dissertations

Very few student-athletes will go on to become a professional in their sport; therefore, the vast majority will need to pursue a non-sport career once their collegiate athletic eligibility has ended. Research indicates that a strong athletic identity and identity foreclosure coincide with lower levels of career maturity, which contributes to the struggle that student-athletes often face with their post-sport transition. The majority of student-athletes compete in nonrevenue-producing collegiate sports (e.g., cross country and soccer), but this subgroup has not been adequately examined. This is problematic because research suggests that lower career maturity levels exist among student-athletes in both revenue- …

Go to article

The Gendered Superhero : An Examination Of Masculinities And Femininities In Modern Age Dc And Marvel Comic Books, Jennifer Volintine Jan 2016

The Gendered Superhero : An Examination Of Masculinities And Femininities In Modern Age Dc And Marvel Comic Books, Jennifer Volintine

Graduate Research Theses & Dissertations

This thesis examines American gender concepts of masculinity and femininity depicted in six Modern Age superhero comic books. Specifically, it examines how the American gender concepts of hegemonic masculinity, hypersexualized masculinity, emphasized femininity, and hypersexualized femininity are depicted in three Marvel and three DC comic books. This examination found that despite gender differences defined by biological essentialism that legitimates gender inequality, female and male superheroes are much more alike than different through what I term "visionary gender". Also, it examines indicators of gender not previously examined in American superhero comic books. In particular, it examines the text of superhero comic …

Go to article

Simulation Analysis Model For Magnetic Drug Delivery To The Targeted Tumor Using External Magnetic Field, Vishnu Priyanka Kadiriboina Jan 2016

Simulation Analysis Model For Magnetic Drug Delivery To The Targeted Tumor Using External Magnetic Field, Vishnu Priyanka Kadiriboina

Graduate Research Theses & Dissertations

The difference between success and failure of chemotherapy depends on not only on the drug itself but also how it is delivered to its target. In current research Magnetic Drug Targeting (MDT) plays an important role in effective drug delivery. Super para-magnetic Nano-particles filled with drug are used as a delivery system for anti-cancer agents in loco regional tumor therapy called magnetic drug targeting. The cancer loco regional tumors are identified and super paramagnetic particles are applied intra arterially close to the tumor region and focused to the tumor by a strong external magnetic field. With the injection of the …

Go to article

Simulation Analysis Of Blood Flow And Selective Drug Particle Delivery To The Targeted Tumors Cerebral Artery-Tissue Region, Sravanthi Patibandla Jan 2016

Simulation Analysis Of Blood Flow And Selective Drug Particle Delivery To The Targeted Tumors Cerebral Artery-Tissue Region, Sravanthi Patibandla

Graduate Research Theses & Dissertations

Brain is the most intricate organ of human body. The development of new therapeutic techniques for Brain tumor diseases is a difficult task, yet these treatments are not effective for almost all the brain diseases. Presence of Blood Brain Barrier (BBB) is the main challenge in development of drugs to treat brain diseases in most of the cases. Among several brain diseases, brain tumors often have poor prognosis, which depends and changes according to the type of the tumor. In this study a three-dimensional computational simulation model for analyzing multifunctional drug distribution through the cerebral artery and adjacent tissue region …

Go to article

Skeletal Indicators Of Hyperpronation In Australopithecus Sediba And Extant Primates, Deanna Goldstein Jan 2016

Skeletal Indicators Of Hyperpronation In Australopithecus Sediba And Extant Primates, Deanna Goldstein

Graduate Research Theses & Dissertations

Habitual bipedal striding locomotion is a distinctive feature of hominins. The human fossil record, however, shows diversity in lower limb anatomy suggesting functional-mechanical differences in locomotion across these fossil taxa. Different forms of bipedality appear in the skeleton of australopithecines such as Australopithecus africanus, Australopithecus afarensis, and Australopithecus sediba. This study seeks to test the hypothesis that australopithecine lower limbs exhibit a mechanically different form of bipedality relative to modern humans, a character that is evident in lower limb flexibility; it is likely that leg flexibility allowed australopithecines to climb trees as well as walk bipedally. In order to test …

Go to article

First Prev Next Last