Digital Commons Network^™

Metric Variation In The Human Sacrum: Costal Process Length Among Black And White South Africans, Christy Rose Wayne

LSU Master's Theses

Considerable attention has been given to the measureable differences that exist between different human populations in the size and shape of the pelvis, with Africans having a narrower pelvis than Europeans. By collecting data on sacral breadth from a South African skeletal population, this study (1) tests the hypothesis that African blacks possess a narrower sacrum, and by inference pelvis, than whites and (2) considers whether the size variation between blacks and whites is due to nutritional, historical and social differences, to a genetic basis related to climatic adaptation, or to both. White South Africans were found to possess a …

Reactivity Of Iron-Sulfur Proteins With Nitric Oxide, Md Julkernine Julfiker

LSU Master's Theses

Iron-sulfur ([Fe-S]) proteins are widely distributed in the biological systems. These proteins are involved in diverse fundamental life processes such as photosynthesis, respiration, ribosome biogenesis, DNA synthesis, and repair. Dysfunction of these proteins or their biogenesis has been implicated in causing cardiovascular diseases, neurodegenerative diseases, and various cancers. Iron-sulfur proteins are highly sensitive to nitric oxide (NO) and readily form dinitrosyl iron complexes (DNICs) upon exposure. Restoration of the iron-sulfur cluster in the NO-modified protein requires a two-step repair process. The first step is to remove DNICs from proteins. The second step is to re-assemble the iron-sulfur cluster in proteins. …

Interrelationships Among Physical Health, Health Risk Factors, Psychosocial Characteristics, And Social Support In Individuals With Major Depressive Disorder Receiving Integrated Care In Community Mental Health Settings, Blaine Stewart Masinter

LSU Master's Theses

Integrated primary and behavioral health care (PBHC) programs in community mental health (CMH) settings is a topic of burgeoning interest in the current literature. These settings aim to counter the health discrepancies and inordinate mortality of persons with serious mental illness (SMI) and comorbid medical conditions. Within the SMI population, the most prevalent diagnosis is Major Depression (MDD). MDD has been well studied in the literature and has been associated with increased rates of physical health conditions. Research has correlated higher levels of social support to lower levels of psychological distress and increased physical health. This cross-sectional, descriptive study examines …

Atp6v1c1 Enhances Breast Cancer Growth By Activating V-Atpase Mediated Mtorc1 Signaling And Metastasis By Increasing V-Atpase Activity In Cancer Cells, Matthew J. Mcconnell

All ETDs from UAB

It is known that the vacuolar ATPase has a number of functions related to tumor growth and progression such as involvement in drug resistance, pH regulation, autophagy, and lysosomal acid protease activation, as well as invasion and metastasis. Here we specifically describe the role of ATP6v1c1 in murine and human models of breast cancer. ATP6v1c1 is the dominant isoform of the coordinating subunit (ATP6v1c) involved in the assembly of the vacuolar ATPase complex which plays a key role in cancer growth and progression. We also describe how ATP6v1c1 knockdown impairs tumor nutrient signaling through mTORC1 and tumor cell proliferation, by …

A Moving Imagination In Spaces Of Distress: Teacher And Student Agency In A Science Classroom, Annie Sunshine Adamian

Doctoral Dissertations

This qualitative study explored the ways in which our classroom community (students and teacher) engaged with humanizing pedagogy in a seventh grade science classroom, toward the full development (e.g. personal, social, emotional, academic) of our classroom community, and the dismantling of inequitable practices and unjust policies that we recognized in our science classroom, school and/or community while utilizing the process of teacher and student participatory action research (tsPAR) (Adamian, 2015) and Critical Race Praxis for Educational Research (CRP-Ed) (Jayakumar & Adamian, 2015).

This study examined the complexities of mutually engaging across differing positionalities while intentionally working in spaces of distress …

An Investigation Of Multimedia Instruction, The Modality Principle, And Reading Comprehension In Fourth-Grade Classrooms, Laura Angela Sandoval

Doctoral Dissertations

Elementary-school teachers are faced with the responsibility of finding the most effective ways to educate their students using multimedia approaches. The use of instruction with visuals and audio has resulted in positive learning outcomes on retention and transfer tasks for junior-high and high-school students. This approach that results in the modality principle has been tested less frequently in elementary-aged students.

The purpose of this study was to examine two different multimedia instructional approaches to investigate which condition offers beneficial learning outcomes through recall and transfer assessments during a lesson on different types of energy in fourth-grade classrooms using a Powerpoint® …

Measurement Of Non-Covalent Aromatic Interactions Using Molecular Balances, Jung Wun Hwang

Theses and Dissertations

Non-covalent aromatic interactions govern many of the unique structures and properties of biological and synthetic molecules. Despite the importance of these interactions, their weak nature makes it challenging to study the interactions. To accurately measure weak non-covalent aromatic interactions in solution, we have designed molecular torsion balances that provide a quantitative measure of non-covalent intramolecular interaction strengths. First, we investigated the importance of electrostatic interactions in aromatic interactions. Substituent effects were strongly correlated with electrostatic Hammett parameters. In addition, the substituent effects were additive and showed significant direct substituent-arene interactions that support the recent direct substituent effect model. Next, the …

Fabrication Of Electrospun Tio2/Polymer Composite Nanofibers For Photocatalysis And Degradation Of Toxins, Danielle L. Mccarthy

Graduate Dissertations and Theses

Our society has made significant advancements in technology as it continues to grow in size which in turn has led to an accumulating amount of toxic threats. Some types of harmful pollution our society is currently facing include industrial waste such as organic dyes, pharmaceutical pollution and chemical warfare agents (CWAs). To date the nerve agent, O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate), also known as VX, is the world’s most lethal chemical substance. Some of these deadly nerve agents have been employed in various conflict and terrorist attacks. Currently available CWA degradation techniques include incineration and water hydrolysis followed by biotreatment …

Leadership Preparation Programs And Social Justice, Lessons Learned From A Graduate School Of Education, Jason Robert Bryant

Theses and Dissertations

This dissertation examines the influence of a graduate school of education on adult learning to determine if transformative learning has taken place. This qualitative study analyzed the stories and experiences of six graduate students to determine if there had been transformative learning and if transformative learning had influenced leadership behaviors that promote social justice in schools. A steady demographic shift over the years has resulted in schools with a higher percentage of minority and poor students. Many of these students are in marginalized in schools. In these marginalized schools, social justice reforms are necessary to address the needs of all …

Modeling Radionuclide Diffusion Using Moose A Multiscale, Multiphysics Platform, Jonathon Gardner

Theses and Dissertations

Very durable ceramic waste forms have been proposed which offer longterm stability by binding certain radionuclides in their specific crystalline network. Moreover, multiple such ceramic phases can be tailored to contain specific radionuclides generated in the fuel cycle. Many such candidate ceramic forms are in the early stages of development with limited data. Modeling and simulation including modeling of diffusion can inform and provide direction to ongoing fabrication and experimental efforts. Material properties important in modeling can be obtained through laboratory measurement where available and atomistic simulation. Since diffusion occurs over multiple scales and follows multiple pathways, multiscale modeling is …

Establishing An Anthropogenic Nitrogen Baseline Using Native American Shell Middens, Autumn Oczkowski, Thomas Gumbley, Bobbi Carter, Ruth Carmichael, Austin T. Humphries

Fisheries, Animal and Veterinary Sciences Faculty Publications

Narragansett Bay, Rhode Island, has been heavily influenced by anthropogenic nutrients for more than 200 years. Recent efforts to improve water quality have cut sewage nitrogen (N) loads to this point source estuary by more than half. Given that the bay has been heavily fertilized for longer than monitoring programs have been in place, we sought additional insight into how N dynamics in the system have historically changed. To do this, we measured the N stable isotope (δ¹⁵N) values in clam shells from as early as 3000 BP to the present. Samples from Native American middens were compared …

The International Health Regulations: The Governing Framework For Global Health Security, Lawrence O. Gostin, Rebecca Katz

Georgetown Law Faculty Publications and Other Works

• The International Health Regulations (IHR) are the governing framework for global health security yet require textual and operational reforms to remain effective, particularly as parallel initiatives are developed.
• The World Health Organization (WHO) is the agency charged with oversight of the IHR, and its leadership and efficient functioning are prerequisites for the effective implementation of the IHR.
• We reviewed the historical origins of the IHR and their performance over the past 10 years and analyzed all of the ongoing reform panel efforts to provide a series of politically feasible recommendations for fundamental reform.
• This article offers proposals for fundamental reform—with …

Collaborative Academic Library Digital Collections Post- Cambridge University Press, Hathitrust And Google Decisions On Fair Use, Michelle M. Wu

Georgetown Law Faculty Publications and Other Works

Academic libraries face numerous stressors as they seek to meet the needs of their users through technological advances while adhering to copyright laws. This paper seeks to explore one specific proposal to balance these interests, the impact of recent decisions on its viability, and the copyright challenges that remain after these decisions.

Maternal Mortality: A Policy Comparison Between Nigeria And India., Rachel Quarles

Dissertations and Theses

A staggering number of women die from preventable deaths each year from causes related to pregnancy and childbirth. India hosts the greatest number of actual maternal deaths in the world, although Nigeria’s ratio of maternal deaths to live births is greater than India’s. This thesis focuses on the experience of these two countries in order to determine if India’s governmental policies, level of government corruption, and traditional practices directly lead to its comparably better maternal health statistics. India has demonstrated lower ratios of maternal mortality and more consistent improvement in maternal health indicators than Nigeria as a result of stronger …

The Adjustment Of First Year African American Women To Predominately White Institutions: Implications For Best Practices, Maisha Beasley

Doctoral Dissertations

Currently, both scholarly literature and educational practice are lacking depth and scope about the lived experience of African American (AA) female students, and, as a result, they lack effectiveness for this population of students. In particular, they do not address the varying ways AA female students adjust to the university during their first year, the most critical year for student retention and persistence in the college experience (Pike & Kuh, 2005), nor do they recognize how intersectionalities of identities in AA women are salient to successes and challenges at PWIs. This study addresses this gap in the research by not …

Workplace Violence, Organizational Culture, And Registered Nurses' Incident Reporting Patterns In Acute Hospitals In California, Feodora Jacobsen

Doctoral Dissertations

The purpose of this study was to increase understanding of the reporting patterns of WPV Type II in acute hospital settings. Although some patients are abusive toward nurses, that the abuse is underreported to hospital administrators. Qualitative studies identified common themes for underreporting including fear of being blamed, abuse considered part of the job, and not having sufficient time to fill out a formal report. This study is the first quantitative study to explore the changes in mean scores of organizational-culture factors under two mutually exclusive conditions: registered nurses (RNs) who do not report hospital incidents and RNs who do …

Organizational Culture And Organization Based Self- Esteem As Predictors Of Spirit At Work, Zeynep Merve Ünal, Tülay Turgut

Khazar Journal of Humanities and Social Sciences

This study aims to investigate the relationships between organizational cultures, spirit at work, and organization based self-esteem among academicians, and whether organization based self-esteem mediates the relationship between organizational culture and spirit at work. A cross-sectional design was employed, and data were collected through a questionnaire-based survey. Based on the convenience sampling, 417 academicians answered the questionnaire in public and private universities located in Turkey. To analyze the data descriptive statistics, Pearson coefficient, simple and multiple regression analyses were conducted. Feminine organizational culture has more positive contribution on experiencing spirit at work than masculine organizational culture. Moreover, organization based self-esteem …

The Evil Defendant And The Holdout Juror: Unpacking The Myths Of The Aurora Theater Shooting Case As We Ponder The Future Of Capital Punishment In Colorado, Kristen Nelson, Tamara Brady, Daniel King

Denver Law Review

No abstract provided.

Local Ecological Knowledge Of Fishermen In Rhode Island And The Dominican Republic: State Of Their Fisheries, Changes And Adaptations, Elizabeth Layli Mclean

Open Access Dissertations

The failure to sustain fisheries is attributed to simultaneous effects of overfishing and to natural disturbance on fish habitats. Many conservation and management efforts are not successful in sustaining the fisheries. There is a growing need to broaden our understanding of people’s knowledge and their fisheries and to consider new approaches that will lead to effective conservation that enables us to sustain fisheries and protect the environment. This study examines the use of fishers’ local ecological knowledge (FEK) to characterize fishing communities and their practices, to assess the state of the fisheries, and the usefulness of this knowledge for conservation …

Toward Intelligent Cyber-Physical Systems: Algorithms, Architectures, And Applications, Bo Tang

Open Access Dissertations

Cyber-physical systems (CPS) are the new generation of engineered systems integrated with computation and physical processes. The integration of computation, communication and control adds new capabilities to the systems being able to interact with physical world. The uncertainty in physical environment makes future CPS to be more reliant on machine learning algorithms which can learn and accumulate knowledge from historical data to support intelligent decision making. Such CPS with the incorporation of intelligence or smartness are termed as intelligent CPS which are safer, more reliable and more efficient.

This thesis studies fundamental machine learning algorithms in supervised and unsupervised manners …

Characterization Of The Role Of The Phosphatase And Tensin Homolog, Pten, In Dna Crosslink Repair, Elizabeth Ann Vuono

Open Access Dissertations

Fanconi Anemia (FA) is a rare autosomal and X-linked disease characterized by multiple congenital abnormalities, progressive bone marrow failure, and cancer predisposition. FA is caused by a biallelic mutation of any one of 21 genes; the proteins encoded by these genes regulate the removal of DNA interstrand crosslinks (ICLs) and are essential for maintaining chromosomal stability. This pathway is tightly regulated by posttranslational modifications (PTMs) such as ubiquitination and phosphorylation. Several kinases such as ATM, ATR and PLK1 have been linked to the pathway but no phosphatase has been firmly linked to the pathway. PTEN is a duel specificity phosphatase, …

Western Australian Biosecurity Strategy 2016 - 2025 Summary, Department Of Agriculture And Food, Western Australia

Biosecurity published reports

This document is a summary of the Western Australian biosecurity strategy 2016 - 2025.

Vision

The vision of WA’s Biosecurity Strategy is ‘working together to minimise the risks to the state’s economic development, environmental assets and social amenity from terrestrial and aquatic pests and diseases’.

Purpose

The purpose of the Strategy is to set the overall direction for the management of emerging and ongoing biosecurity issues within WA from 2016 to 2025.

Scope

The Strategy covers animal and plant pests, diseases and weeds, and zoonotic diseases that can be transmitted between animals and humans. These have the potential to negatively …

Coordination Of Rna Polymerase Ii Pausing And 3' End Processing Factor Recruitment With Alternative Polyadenylation, Becky Fusby, Soojin Kim, Benjamin Erickson, Hyunmin Kim, Martha L. Peterson, David L Bentley

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Most mammalian genes produce transcripts whose 3' ends are processed at multiple alternative positions by cleavage/polyadenylation (CPA). Poly(A) site cleavage frequently occurs cotranscriptionally and is facilitated by CPA factor binding to the RNA polymerase II (Pol II) C-terminal domain (CTD) phosphorylated on Ser2 residues of its heptad repeats (YS₂PTSPS). The function of cotranscriptional events in the selection of alternative poly(A) sites is poorly understood. We investigated Pol II pausing, CTD Ser2 phosphorylation, and processing factor CstF recruitment at wild-type and mutant IgM transgenes that use alternative poly(A) sites to produce mRNAs encoding the secreted and membrane-bound forms of …

Michigan Academician, Volume 43, Issue 1

Michigan Academician

No abstract provided.

Michigan Academician, Volume 43, Issue 2

Michigan Academician

No abstract provided.

Michigan Academician, Volume 44, Issue 2

Michigan Academician

No abstract provided.

Tninvestco Annual Report 2016, Tennessee. Department Of Economic And Community Development

Annual Reports

The TNInvestCo annual report reflects figures reported by each TNInvestCo related to investment activity. The summary section reflects adjusted figures of the TNInvestCo program where the duplication of jobs and follow-on capital have been removed.

Acceptability And Feasibility Of Introducing Strengthened School-Based Sexual And Reproductive Health Information And Services In Accra, Ghana, Terence Adda-Balinia, Philip Teg-Nefaah Tabong, Maya Teye, Philip Baba Adongo, Placide Tapsoba, Harriet Birungi

Reproductive Health

An initial study conducted by Population Council under the Strengthening Evidence for Programming on Unintended Pregnancies (STEP UP) project in 2012 assessed the knowledge and reproductive health needs of adolescents living in selected slums in Brong Ahafo and Greater Accra regions with the view of informing an improvement in adolescent sexual health (ASRH) programming in Ghana. The study concludes that stakeholders generally believed there was the need for enhanced adolescent sexual and reproductive health services in school as the present system of delivering these services were not sufficiently addressing ASRH needs. The use of trained psychologists and health workers was …

Health Impacts Of Female Genital Mutilation/Cutting: A Synthesis Of The Evidence, Samuel Kimani, Jacinta Muteshi-Strachan, Carolyne Njue

Reproductive Health

The Africa Coordinating Centre for the Abandonment of Female Genital Mutilation/Cutting, with support from the Population Council, sought to synthesize the evidence on the health impacts of female genital mutilation/cutting (FGM/C), identify recommended interventions, and compile and analyze the existing reference materials. The goal of this review is to inform the development of a comprehensive set of training guidelines and materials for frontline healthcare providers so they can manage the care of women and girls who have undergone FGM/C, prevent the practice at the community level, and accelerate abandonment of FGM/C practices. This analysis underscores the health impacts associated with …

A Systematic Review Of The Treatment And Management Of Pre-Eclampsia And Eclampsia In Nigeria, Karen Kirk, Ishita Chattopadhyay

Reproductive Health

Throughout the development of a pregnancy, there are many opportunities when pre-eclampsia and eclampsia (PE/E) can be prevented, detected, and managed; based on the literature, certain gaps exist along this continuum of care. To fully appreciate the enormity of the problem at the country level, the Population Council conducted a systematic review of published papers on PE/E in Nigeria from 2000–15 in order to understand the key challenges, gaps, and interventions related to the prevention and treatment of PE/E. In order to have the most impact, this report recommends a multi-level set of interventions that increase community awareness of symptoms …