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2016

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Articles 23251 - 23280 of 29046

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Metabolic Requirements Of Escherichia Coli In Intracellular Bacterial Communities During Urinary Tract Infection Pathogenesis, Matt S. Conover, Maria Hadjifrangiskou, Joseph J. Palermo, Michael E. Hibbing, Karen W. Dodson, Scott J. Hultgren Jan 2016

Metabolic Requirements Of Escherichia Coli In Intracellular Bacterial Communities During Urinary Tract Infection Pathogenesis, Matt S. Conover, Maria Hadjifrangiskou, Joseph J. Palermo, Michael E. Hibbing, Karen W. Dodson, Scott J. Hultgren

Open Access Publications

No abstract provided.


Hyperexpansion Of Rna Bacteriophage Diversity, Siddharth R. Krishnamurthy, Andrew B. Janowski, Guoyan Zhao, Dan Barouch, David Wang Jan 2016

Hyperexpansion Of Rna Bacteriophage Diversity, Siddharth R. Krishnamurthy, Andrew B. Janowski, Guoyan Zhao, Dan Barouch, David Wang

Open Access Publications

No abstract provided.


Rapid Quantitative Pharmacodynamic Imaging With Bayesian Estimation, Jonathan M. Koller, M. Jonathan Vachon, G. Larry Bretthorst, Kevin J. Black Jan 2016

Rapid Quantitative Pharmacodynamic Imaging With Bayesian Estimation, Jonathan M. Koller, M. Jonathan Vachon, G. Larry Bretthorst, Kevin J. Black

Open Access Publications

No abstract provided.


The Association Between Childhood Maltreatment, Psychopathology, And Adult Sexual Victimization In Men And Women: Results From Three Independent Samples, K. B. Werner, V. V. Mccutcheon, M. Challa, A. Agrawal, M. T. Lynskey, E. Conroy, D. J. Statham, P. A. F. Madden, A. K. Henders, A. A. Todorov, A. C. Heath, L. Degenhardt, N. G. Martin, K. K. Bucholz, E. C. Nelson Jan 2016

The Association Between Childhood Maltreatment, Psychopathology, And Adult Sexual Victimization In Men And Women: Results From Three Independent Samples, K. B. Werner, V. V. Mccutcheon, M. Challa, A. Agrawal, M. T. Lynskey, E. Conroy, D. J. Statham, P. A. F. Madden, A. K. Henders, A. A. Todorov, A. C. Heath, L. Degenhardt, N. G. Martin, K. K. Bucholz, E. C. Nelson

Open Access Publications

No abstract provided.


Mesothelin's Minimal Muc16 Binding Moiety Converts Tr3 Into A Potent Cancer Therapeutic Via Hierarchical Binding Events At The Plasma Membrane, Yang Su, Katharina Tatzel, Xuejun Wang, Brian Belt, Pratibha Binder, Lindsay Kuroki, Matthew A. Powell, David G. Mutch, William G. Hawkins, Dirk Spitzer Jan 2016

Mesothelin's Minimal Muc16 Binding Moiety Converts Tr3 Into A Potent Cancer Therapeutic Via Hierarchical Binding Events At The Plasma Membrane, Yang Su, Katharina Tatzel, Xuejun Wang, Brian Belt, Pratibha Binder, Lindsay Kuroki, Matthew A. Powell, David G. Mutch, William G. Hawkins, Dirk Spitzer

Open Access Publications

No abstract provided.


Role Of Wdhd1 In Human Papillomavirus-Mediated Oncogenesis Identified By Transcriptional Profiling Of E7-Expressing Cells, Yunying Zhou, Qishu Zhang, Ge Gao, Xiaoli Zhang, Yafei Liu, Shoudao Yuan, Xiaowei Wang, Jason J. Chen Jan 2016

Role Of Wdhd1 In Human Papillomavirus-Mediated Oncogenesis Identified By Transcriptional Profiling Of E7-Expressing Cells, Yunying Zhou, Qishu Zhang, Ge Gao, Xiaoli Zhang, Yafei Liu, Shoudao Yuan, Xiaowei Wang, Jason J. Chen

Open Access Publications

No abstract provided.


Metabolic Alterations In Children With Environmental Enteric Dysfunction, Richard D. Semba, Michelle Shardell, Indi Trehan, Ruin Moaddel, Kenneth M. Maleta, M. Isabel Ordiz, Klaus Kraemer, Mohammed Khadeer, Luigi Ferrucci, Mark J. Manary Jan 2016

Metabolic Alterations In Children With Environmental Enteric Dysfunction, Richard D. Semba, Michelle Shardell, Indi Trehan, Ruin Moaddel, Kenneth M. Maleta, M. Isabel Ordiz, Klaus Kraemer, Mohammed Khadeer, Luigi Ferrucci, Mark J. Manary

Open Access Publications

No abstract provided.


Identification Of Putative Geographically Isolated Wetlands Of The Conterminous United States, Charles R. Lane, Ellen D'Amico Jan 2016

Identification Of Putative Geographically Isolated Wetlands Of The Conterminous United States, Charles R. Lane, Ellen D'Amico

United States Environmental Protection Agency: Publications

Geographically isolated wetlands (GIWs) are wetlands completely surrounded by uplands. While common throughout the United States (U.S.), there have heretofore been no nationally available, spatially explicit estimates of GIW extent, complicating efforts to understand the myriad biogeochemical, hydrological, and habitat functions of GIWs and hampering conservation and management efforts at local, state, and national scales. We used a 10-m geospatial buffer as a proxy for hydrological or ecological connectivity of National Wetlands Inventory palustrine and lacustrine wetland systems to nationally mapped and available stream, river, and lake data. We identified over 8.3 million putative GIWs across the conterminous U.S., encompassing …


Water Consumption Estimates Of The Biodiesel Process In The Us, Qingshi Tu, Mingming Lu, Y. Jeffrey Yang, Don Scott Jan 2016

Water Consumption Estimates Of The Biodiesel Process In The Us, Qingshi Tu, Mingming Lu, Y. Jeffrey Yang, Don Scott

United States Environmental Protection Agency: Publications

As a renewable alternative to petroleum diesel, biodiesel has been widely used in the US and the world. However, its potential impact on water resources has not been much evaluated. This study investigates water consumption from the biodiesel process, which includes three stages: soybean irrigation, soybean-to-soybean oil processing, and biodiesel manufacturing, at both national and state levels. Mass-based allocation is performed and water consumption at the three stages is obtained on the basis of million gallons per year and gallon water per gallon biodiesel (gal/gal). The normalized water consumption (water intensity) of the irrigation, oil processing, and biodiesel production stages …


Quantitative Structure–Mesothelioma Potency Model Optimization For Complex Mixtures Of Elongated Particles In Rat Pleura: A Retrospective Study, Philip M. Cook, Joseph Swintek, Timothy D. Dawson, David Chapman, Mathew A. Etterson, Dale Hoff Jan 2016

Quantitative Structure–Mesothelioma Potency Model Optimization For Complex Mixtures Of Elongated Particles In Rat Pleura: A Retrospective Study, Philip M. Cook, Joseph Swintek, Timothy D. Dawson, David Chapman, Mathew A. Etterson, Dale Hoff

United States Environmental Protection Agency: Publications

Cancer potencies of mineral and synthetic elongated particle mixtures, including asbestos fibers, are influenced by changes in fiber dose composition, bioavailability, and biodurability in combination with relevant cytotoxic dose-response relationships. An extensive rat intrapleural dose characterization data set with a wide variety of elongated particles physicochemical properties facilitated statistical analyses of pleural mesothelioma response data combined from several studies for evaluation of alternative dose-response models. Utilizing logistic regression of individual elongated particle dimensional variations within each test sample, four major findings emerged: (1) Mild acid leaching provides superior prediction of tumor incidence compared to samples that were not leached; (2) …


Nanofiber Scaffolds Influence Organelle Structure And Function In Bone Marrow Stromal Cells, Wojtek Tutak, Giri Jyotsnendu, Peter Bajcsy, Carl G. Simon Jr. Jan 2016

Nanofiber Scaffolds Influence Organelle Structure And Function In Bone Marrow Stromal Cells, Wojtek Tutak, Giri Jyotsnendu, Peter Bajcsy, Carl G. Simon Jr.

United States Department of Commerce: Staff Publications

Recent work demonstrates that osteoprogenitor cell culture on nanofiber scaffolds can promote differentiation. This response may be driven by changes in cell morphology caused by the three-dimensional (3D) structure of nanofibers. We hypothesized that nanofiber effects on cell behavior may be mediated by changes in organelle structure and function. To test this hypothesis, human bone marrow stromal cells (hBMSCs) were cultured on poly(ϵ-caprolactone) (PCL) nanofibers scaffolds and on PCL flat spuncoat films. After 1 day-culture, hBMSCs were stained for actin, nucleus, mitochondria, and peroxisomes, and then imaged using 3D confocal microscopy. Imaging revealed that the hBMSC cell body (actin) and …


Zika Virus: New Clinical Syndromes And Its Emergence In The Western Hemisphere, Helen M. Lazear, Michael S. Diamond Jan 2016

Zika Virus: New Clinical Syndromes And Its Emergence In The Western Hemisphere, Helen M. Lazear, Michael S. Diamond

Open Access Publications

No abstract provided.


Absorbed Radiation Dosimetry Of The D3-Specific Pet Radioligand [18f]Fluortriopride Estimated Using Rodent And Nonhuman Primate, Richard Laforest, Morvarid Karimi, Stephen M. Moerlein, Jinbin Xu, Hubert P. Flores, Christopher Bognar, Aixiao Li, Robert H. Mach, Joel S. Perlmutter, Zhude Tu Jan 2016

Absorbed Radiation Dosimetry Of The D3-Specific Pet Radioligand [18f]Fluortriopride Estimated Using Rodent And Nonhuman Primate, Richard Laforest, Morvarid Karimi, Stephen M. Moerlein, Jinbin Xu, Hubert P. Flores, Christopher Bognar, Aixiao Li, Robert H. Mach, Joel S. Perlmutter, Zhude Tu

Open Access Publications

No abstract provided.


The Nad World 2.0: The Importance Of The Inter-Tissue Communication Mediated By Nampt/Nad+/Sirt1 In Mammalian Aging And Longevity Control, Shin-Ichiro Imai Jan 2016

The Nad World 2.0: The Importance Of The Inter-Tissue Communication Mediated By Nampt/Nad+/Sirt1 In Mammalian Aging And Longevity Control, Shin-Ichiro Imai

Open Access Publications

No abstract provided.


It Takes Two To Tango: Nad+ And Sirtuins In Aging/Longevity Control, Shin-Ichiro Imai, Leonard Guarente Jan 2016

It Takes Two To Tango: Nad+ And Sirtuins In Aging/Longevity Control, Shin-Ichiro Imai, Leonard Guarente

Open Access Publications

No abstract provided.


Prospective Exploratory Muscle Biopsy, Imaging, And Functional Assessment In Patients With Late-Onset Pompe Disease Treated With Alglucosidase Alfa: The Embassy Study, Alan Pestronk, Et Al Jan 2016

Prospective Exploratory Muscle Biopsy, Imaging, And Functional Assessment In Patients With Late-Onset Pompe Disease Treated With Alglucosidase Alfa: The Embassy Study, Alan Pestronk, Et Al

Open Access Publications

No abstract provided.


Chronic Contractile Dysfunction Without Hypertrophy Does Not Provoke A Compensatory Transcriptional Response In Mouse Hearts, Scot J. Matkovich, David R. Grubb, Julie R. Mcmullen, Elizabeth A. Woodcock Jan 2016

Chronic Contractile Dysfunction Without Hypertrophy Does Not Provoke A Compensatory Transcriptional Response In Mouse Hearts, Scot J. Matkovich, David R. Grubb, Julie R. Mcmullen, Elizabeth A. Woodcock

Open Access Publications

No abstract provided.


General Framework For Meta-Analysis Of Haplotype Association Tests, Ping An, Ingrid B. Borecki, Michael A. Province, Et Al Jan 2016

General Framework For Meta-Analysis Of Haplotype Association Tests, Ping An, Ingrid B. Borecki, Michael A. Province, Et Al

Open Access Publications

No abstract provided.


Challenges In Drug Discovery For Neurofibromatosis Type 1-Associated Low-Grade Glioma, Cora A. Ricker, Yuan Pan, David H. Gutmann, Charles Keller Jan 2016

Challenges In Drug Discovery For Neurofibromatosis Type 1-Associated Low-Grade Glioma, Cora A. Ricker, Yuan Pan, David H. Gutmann, Charles Keller

Open Access Publications

No abstract provided.


Genetic Association Of Long-Chain Acyl-Coa Synthetase 1 Variants With Fasting Glucose, Diabetes, And Subclinical Atherosclerosis, Ani Manichaikul, Xin-Qun Wang, Wei Zhao, Mary K. Wojczynski, Kyle Siebenthall, John A. Stamatoyannopoulos, Danish Saleheen, Ingrid B. Borecki, Muredach P. Reilly, Stephen S. Rich, Karin E. Bornfeldt Jan 2016

Genetic Association Of Long-Chain Acyl-Coa Synthetase 1 Variants With Fasting Glucose, Diabetes, And Subclinical Atherosclerosis, Ani Manichaikul, Xin-Qun Wang, Wei Zhao, Mary K. Wojczynski, Kyle Siebenthall, John A. Stamatoyannopoulos, Danish Saleheen, Ingrid B. Borecki, Muredach P. Reilly, Stephen S. Rich, Karin E. Bornfeldt

Open Access Publications

No abstract provided.


Atypical Manifestations Of Cutaneous Leishmaniasis In A Region Endemic For Leishmania Braziliensis: Clinical, Immunological And Parasitological Aspects, Luiz Henrique Guimaraes, Adriano Queiroz, Juliana A. Silva, Silvana C. Silva, Viviane Magalhaes, Ednaldo L. Lago, Paulo Roberto L. Machado, Olivia Bacellar, Mary E. Wilson, Stephen M. Beverly, Edgar M. Carvalho, Albert Schriefer Jan 2016

Atypical Manifestations Of Cutaneous Leishmaniasis In A Region Endemic For Leishmania Braziliensis: Clinical, Immunological And Parasitological Aspects, Luiz Henrique Guimaraes, Adriano Queiroz, Juliana A. Silva, Silvana C. Silva, Viviane Magalhaes, Ednaldo L. Lago, Paulo Roberto L. Machado, Olivia Bacellar, Mary E. Wilson, Stephen M. Beverly, Edgar M. Carvalho, Albert Schriefer

Open Access Publications

No abstract provided.


Mechanisms Of Zika Virus Infection And Neuropathogenesis, David Olagnier, Michela Muscolini, Carolyn B. Coyne, Michael S. Diamond, John Hiscott Jan 2016

Mechanisms Of Zika Virus Infection And Neuropathogenesis, David Olagnier, Michela Muscolini, Carolyn B. Coyne, Michael S. Diamond, John Hiscott

Open Access Publications

No abstract provided.


Associations Between Polygenic Risk For Psychiatric Disorders And Substance Involvement, Caitlin E. Carey, Arpana Agrawal, Kathleen K. Bucholz, Sarah M. Hartz, Michael T. Lynskey, Elliot C. Nelson, Laura J. Bierut, Ryan Bogdan Jan 2016

Associations Between Polygenic Risk For Psychiatric Disorders And Substance Involvement, Caitlin E. Carey, Arpana Agrawal, Kathleen K. Bucholz, Sarah M. Hartz, Michael T. Lynskey, Elliot C. Nelson, Laura J. Bierut, Ryan Bogdan

Open Access Publications

No abstract provided.


Axonal Growth Arrests After An Increased Accumulation Of Schwann Cells Expressing Senescence Markers And Stromal Cells In Acellular Nerve Allografts, Louis H. Poppler, Xueping Ee, Lauren Schellhardt, Gwendolyn M. Hoben, Deng Pan, Daniel A. Hunter, Ying Yan, Amy M. Moore, Alison K. Snyder-Warwick, Sheila A. Stewart, Susan E. Mackinnon, Matthew D. Wood Jan 2016

Axonal Growth Arrests After An Increased Accumulation Of Schwann Cells Expressing Senescence Markers And Stromal Cells In Acellular Nerve Allografts, Louis H. Poppler, Xueping Ee, Lauren Schellhardt, Gwendolyn M. Hoben, Deng Pan, Daniel A. Hunter, Ying Yan, Amy M. Moore, Alison K. Snyder-Warwick, Sheila A. Stewart, Susan E. Mackinnon, Matthew D. Wood

Open Access Publications

No abstract provided.


Personality Polygenes, Positive Affect, And Life Satisfaction, Andrew C. Heath, Et Al Jan 2016

Personality Polygenes, Positive Affect, And Life Satisfaction, Andrew C. Heath, Et Al

Open Access Publications

No abstract provided.


Cardiomyocyte-Specific Ablation Of Med1 Subunit Of The Mediator Complex Causes Lethal Dilated Cardiomyopathy In Mice, Yuzhi Jia, Hsiang-Chun Chang, Matthew J. Schipma, Jing Liu, Varsha Shete, Ning Liu, Tatsuya Sato, Edward B. Thorp, Philip M. Barger, Yi-Jun Zhu, Navin Viswakarma, Yashpal S. Kanwar, Hossein Ardehali, Bayar Thimmapaya, Janardan K. Reddy Jan 2016

Cardiomyocyte-Specific Ablation Of Med1 Subunit Of The Mediator Complex Causes Lethal Dilated Cardiomyopathy In Mice, Yuzhi Jia, Hsiang-Chun Chang, Matthew J. Schipma, Jing Liu, Varsha Shete, Ning Liu, Tatsuya Sato, Edward B. Thorp, Philip M. Barger, Yi-Jun Zhu, Navin Viswakarma, Yashpal S. Kanwar, Hossein Ardehali, Bayar Thimmapaya, Janardan K. Reddy

Open Access Publications

No abstract provided.


Cardiac Arrest-Induced Global Brain Hypoxia-Ischemia During Development Affects Spontaneous Activity Organization In Rat Sensory And Motor Thalamocortical Circuits During Adulthood, Michael Shoykhet, Jason W. Middleton Jan 2016

Cardiac Arrest-Induced Global Brain Hypoxia-Ischemia During Development Affects Spontaneous Activity Organization In Rat Sensory And Motor Thalamocortical Circuits During Adulthood, Michael Shoykhet, Jason W. Middleton

Open Access Publications

No abstract provided.


Contact-Facilitated Drug Delivery With Sn2 Lipase Labile Prodrugs Optimize Targeted Lipid Nanoparticle Drug Delivery, Dipanjan Pan, Christine T.N. Pham, Katherine N. Weilbaecher, Michael H. Tomasson, Samuel A. Wickline, Gregory M. Lanza Jan 2016

Contact-Facilitated Drug Delivery With Sn2 Lipase Labile Prodrugs Optimize Targeted Lipid Nanoparticle Drug Delivery, Dipanjan Pan, Christine T.N. Pham, Katherine N. Weilbaecher, Michael H. Tomasson, Samuel A. Wickline, Gregory M. Lanza

Open Access Publications

No abstract provided.


Cost-Effective Recruitment Strategies That Attract Underrepresented Minority Undergraduates Who Persist To Stem Doctorates, Cherilynn R. Shadding, Dawayne Whittington, Latricia E. Wallace, Wambul S. Wandu, Richard K. Wilson Jan 2016

Cost-Effective Recruitment Strategies That Attract Underrepresented Minority Undergraduates Who Persist To Stem Doctorates, Cherilynn R. Shadding, Dawayne Whittington, Latricia E. Wallace, Wambul S. Wandu, Richard K. Wilson

Open Access Publications

No abstract provided.


Illustrating And Homology Modeling The Proteins Of The Zika Virus [Version 2; Referees: 2 Approved], Sean Ekins, John Liebler, Bruno J. Neves, Warren G. Lewis, Megan Coffee, Rachelle Bienstock, Christopher Southan, Carolina H. Andrade Jan 2016

Illustrating And Homology Modeling The Proteins Of The Zika Virus [Version 2; Referees: 2 Approved], Sean Ekins, John Liebler, Bruno J. Neves, Warren G. Lewis, Megan Coffee, Rachelle Bienstock, Christopher Southan, Carolina H. Andrade

Open Access Publications

No abstract provided.