Digital Commons Network^™

Lab Roster 2016, Booth Library

Rosters

No abstract provided.

Playing With Knives: The Socialization Of Self-Initiated Learners, David F. Lancy

Sociology, Social Work and Anthropology Faculty Publications

Since Margaret Mead’s field studies in the South Pacific a century ago, there has been the tacit understanding that as culture varies, so too must the socialization of children to become competent culture users and bearers. More recently, the work of anthropologists has been mined to find broader patterns that may be common to childhood across a range of societies. One improbable commonality has been the tolerance, even encouragement, of toddler behavior that is patently risky, such as playing with or attempting to use a sharp-edged tool. This laissez faire approach to socialization follows from a reliance on children as …

Functional Analysis Of Rpl22: Coordinating Differentiation Signals And Developmental Gene Translation To Promote Cell Fate Decisions, Stephen Kim

Graduate School of Biomedical Sciences Theses and Dissertations

The execution of meiosis and spore formation in S. cerevisiae requires a transient transcription program that is initiated by Ime I-dependent destruction of the repressor Ume6. IMEJ transcription is tightly contro1led by both cell type and nutritional cues but how its translation is regulated has been unknown. This study demonstrates that Rpl22A and Rpl22B, eukaryotic-specific ribosomal protein paralogs of the 60S large subunit, are required for efficient Ime I translation. While IME1 mRNA is induced normally in the absence of both para logs following transfer to sporulation medium, Ume6 remains stabilized, downstream early meiotic gene remain repressed, and development is …

A Mathematical Model For Feral Cat Ecology With Application To Disease., Jeff Sharpe

Electronic Theses and Dissertations

We formulate and analyze a mathematical model for feral cats living in an isolated colony. The model contains compartments for kittens, adult females and adult males. Kittens are born at a rate proportional to the population of adult females and mature at equal rates into adult females and adult males. Adults compete with each other in a manner analogous to Lotka-Volterra competition. This competition comes in four forms, classified by gender. Native house cats, and their effects are also considered, including additional competition and abandonment into the feral population. Control measures are also modeled in the form of per-capita removal …

Understanding Hydroclimatic Controls On Stream Network Dynamics Using Lidar Data, Seoyoung Kim

Electronic Theses and Dissertations

This dissertation investigates the hydroclimatic controls on drainage network dynamics and characterizes the variation of drainage density in various climate regions. The methods were developed to extract the valley and wet channel networks based on Light Detection and Ranging (LiDAR) data including the elevation and intensity of laser returns. The study watersheds were selected based on the availability of streamflow observations and LiDAR data. Climate aridity index was used as a quantitative indicator for climate. The climate controls on drainage density were re-visited using watersheds with minimal anthropogenic interferences and compared with the U-shape relationship reported in the previous studies. …

Ua35/3 Memoranda, Wku Provost

WKU Administration Documents

Memoranda issued by the WKU Provost to WKU faculty and staff through email in 2016.

• Outstanding Mentoring in Undergraduate Research / Creative Activity
• 2016 Faculty Awards Reception
• Associate Provost of Research & Creative Activity
• Dean of Graduate School

Service-Learning At Dominican: Education In Action, Julia Van Der Ryn

Collected Faculty Scholarship

What is Service-Learning at Dominican?

Service-Learning (SL) puts education into action by engaging with the community and experiencing the relevance of coursework first-hand. SL expands the classroom into the local community, providing the opportunity to apply classroom content to work with local community organizations and schools, learning about the lives of others, developing awareness, enhancing one’s understanding of how we can contribute to social justice issues that ultimately impact us all.

Through SL, students develop practical, transferable skills, explore career and personal interests, and expand their networks and sense of self while connecting with other students, faculty, and community mentors.

The Periodical Winter 2016, Southern Adventist University

the Periodical – Chemistry Department Newsletter

Volume 3, issue 2 of the Periodical includes articles about the Chemistry Club's community service, a pictorial listing of May 2016 graduates, student Jeron Estwick's presentation at a chemistry conference, a feature on students recognized for academic achievement, and an alumni spotlight.

The Effects Of Cold And Freezing Temperatures On The Blood Brain Barrier And Aquaporin 1, 4, And 9 Expression In Cope's Gray Treefrog (Hyla Chrysoscelis), Dalal Nouruldeen Felemban

Browse all Theses and Dissertations

In sub-freezing temperatures, cerebrospinal fluid (CSF) and blood plasma within the brain of freeze-tolerant gray treefrogs, Hyla chrysoscelis, are likely to freeze. We hypothesized that this would challenge blood-brain barrier (BBB) integrity and volume regulation for cells in the brain. Our first hypothesis, tested as cerebral Evans blue permeability, was not supported; BBB integrity appeared uncompromised by cold. Our second hypothesis, tested as changing expression of aquaporin (AQP) proteins, was partially supported. Whole-brain expression (Western blot) of AQP1 and AQP4 were unchanged by cold conditions, but AQP9 expression increased in thawed animals. AQP1 was found (immunohistochemistry) in ependymal cells, endothelial …

Forage Yields In Turkey Hill Wilderness In East Texas For White-Tailed Deer, Brian P. Oswald, Kenneth W. Farrish, Bret Gentzler

Faculty Publications

Wilderness areas are often considered quality areas where natural processes occur without human activity. It is often assumed that these unmanaged areas will provide and support quality wildlife habitat. The objective of this study was to evaluate the forage production and stocking potential of an unmanaged wilderness area in east Texas. Four different community types were evaluated for forage yield, forage availability, and browse utilization for white-tailed deer. Results show that although a wide range of forage yields were measured in the spring, summer forage yield did not differ among the various communities. Availability also differed between community types, but …

Endocidal Regulation Of Secondary Metabolites In The Producing Organisms, Shiyou Li, Ping Wang, Wei Yuan, Zushang Su, Steven H. Bullard

Faculty Publications

Secondary metabolites are defined as organic compounds that are not directly involved in the normal growth, development, and reproduction of an organism. They are widely believed to be responsible for interactions between the producing organism and its environment, with the producer avoiding their toxicities. In our experiments, however, none of the randomly selected 44 species representing different groups of plants and insects can avoid autotoxicity by its endogenous metabolites once made available. We coined the term endocides (endogenous biocides) to describe such metabolites that can poison or inhibit the parent via induced biosynthesis or external applications. Dosage-dependent endocides can selectively …

Spatial Distribution Of Earthworms In An East Texas Forest Ecosystem, Melissa A. Bozarth, Kenneth W. Farrish, George A. Damoff, James Van Kley, J. Leon Young

Faculty Publications

Earthworms were collected and identified in different ecological habitats of the Stephen F. Austin Experimental Forest (SFAEF) in the Piney Woods Ecoregion (PWE) of Texas. Earthworm spatial distribution data were collected over four distinct ecological habitats with a range of soil conditions and vegetative cover. A total of 128 sampling plots were surveyed in two different, broadly defined locations (mesic slope = 68 plots, dry-mesic upland = 60 plots). Using multivariate classification/ordination (TWINSPAN) and detrended correspondence analysis (DCA) of overstory vegetation data, these two locations were further divided into four distinct habitats: dry-mesic mixed upland, transitional zone, mesic slope and …

Biological, Environmental, And Social Influences On Childhood Obesity, M. Karen Campbell

Paediatrics Publications

The prevalence of childhood obesity has increased globally over the past three decades, with evidence of recent leveling off in developed countries. Reduction in the, currently high, prevalence of obesity will require a full understanding of the biological and social pathways to obesity in order to develop appropriately targeted prevention strategies in early life. Determinants of childhood obesity include individual level factors, including biological, social, and behavioral risks, acting within the influence of the child's family environment, which is, in turn, imbedded in the context of the community environment. These influences act across childhood, with suggestions of early critical periods …

Aristotle's Clivus Naturae, John Thorp

Philosophy Presentations

It is usually thought that Aristotle's understanding of the soul sees it has having four distinct parts, cumulatively arranged, resulting in a kind of scala or ladder: all living things have the nutritive and reproductive soul; animals have, in addition, the sensitive soul, and most of them also the locomotive soul; only humans have all these plus the intellective soul. This ladder-like picture emerges from his theoretical work de Anima. In his more empirical studies, though, the discreteness of these levels is softened, and the image is more that of a clivus or slope, rather than a scala or ladder …

Integrin-Linked Kinase Is Indispensable For Keratinocyte Differentiation And Epidermal Barrier Function, Samar Sayedyahossein, Alena Rudkouskaya, Valerie Leclerc, Lina Dagnino

Paediatrics Publications

A functional permeability barrier is essential to prevent the passage of water and electrolytes, macromolecules, and pathogens through the epidermis. This is accomplished in terminally differentiated keratinocytes through formation of a cornified envelope and the assembly of tight intercellular junctions. Integrin-linked kinase (ILK) is a scaffold protein essential for hair follicle morphogenesis and epidermal attachment to the basement membrane. However, the biological functions of ILK in differentiated keratinocytes remain poorly understood. Furthermore, whether ILK is implicated in keratinocyte differentiation and intercellular junction formation has remained an unresolved issue. Here we describe a pivotal role for ILK in keratinocyte differentiation responses …

Unravelling The Mechanism Of Trka-Induced Cell Death By Macropinocytosis In Medulloblastoma Daoy Cells, Chunhui Li, James I.S. Macdonald, Asghar Talebian, Jennifer Leuenberger, Claudia Seah, Stephen H. Pasternak, Stephen W. Michnick, Susan O. Meakin

Paediatrics Publications

Macropinocytosis is a normal cellular process by which cells internalize extracellular fluids and nutrients from their environment and is one strategy that Ras-transformed pancreatic cancer cells use to increase uptake of amino acids to meet the needs of rapid growth. Paradoxically, in non-Ras transformed medulloblastoma brain tumors, we have shown that expression and activation of the receptor tyrosine kinase TrkA overactivates macropinocytosis, resulting in the catastrophic disintegration of the cell membrane and in tumor cell death. The molecular basis of this uncontrolled form of macropinocytosis has not been previously understood. Here, we demonstrate that the overactivation of macropinocytosis is caused …

Assortative Mating But No Evidence Of Genetic Divergence In A Species Characterized By A Trophic Polymorphism, Scott F. Coborne, S R. Garner, Fred Longstaffe, Bryan D. Neff

Earth Sciences Publications

Disruptive selection is a process that can result in multiple sub-groups within a population, referred to as diversification. Foraging related divergence has been described in many taxa, but many questions remain about the contribution of such divergence to reproductive isolation and potentially sympatric speciation. Here we use stable isotope analysis of diet and morphological analysis of body shape to examine phenotypic divergence between littoral and pelagic foraging ecomorphs in a population of pumpkinseed sunfish (Lepomis gibbosus). We then examine reproductive isolation between ecomorphs by comparing the isotopic compositions of nesting males to eggs from their nests (a proxy for maternal …

Microbially Induced Sedimentary Structures In The Paleoproterozoic, Upper Huronian Supergroup, Canada, Carolyn Hill, Patricia I. Corcoran, Rohan Aranha, Fred Longstaffe

Earth Sciences Publications

The Paleoproterozoic Gordon Lake and Bar River formations, Huronian Supergroup, contain a variety of sedimentary structures in the Flack Lake area of Ontario, Canada, that have been considered of debatable origin. We identify these structures as microbially induced sedimentary structures (MISS). The preserved MISS are related to microbial mat destruction and decay, and include sand cracks, mat chips, remnant gas domes, pyrite patches, and iron laminae. A biological origin for the fossil structures is supported by their similarities to modern and ancient documented examples of MISS, the sand-dominated nature of the substrate in which they are preserved, and key microtextures …

Dentine Oxygn Isotopes (Δ18o) As A Proxy For Odontocete Distributions And Movements., Cory J.D. Matthews, Fred J. Longstaffe, Steven H. Fergispm

Earth Sciences Publications

Spatial variation in marine oxygen isotope ratios ( δ¹⁸O) resulting from differential evaporation rates and precipitation inputs is potentially useful for characterizing marine mammal distributions and tracking movements across δ¹⁸O gradients. Dentine hydroxyapatite contains carbonate and phosphate that precipitate in oxygen isotopic equilibrium with body water, which in odontocetes closely tracks the isotopic composition of ambient water. To test whether dentine oxygen isotope composition reliably records that of ambient water and can therefore serve as a proxy for odontocete distribution and movement patterns, we measured δ¹⁸O values of dentine structural carbonate (δ^{18 …}

Early Horizon Camelid Management Practices In The Nepeña Valley, North-Central Coast Of Peru, Paul Szpak, David Chicone, Jean-François Millaire, Christine D. White, Rebecca Parry, Fred Longstaffe

Earth Sciences Publications

South American camelids (llamas and alpacas) were of great economic, social and ritual significance in the pre-Hispanic Andes. Although these animals are largely limited to high-altitude (>3500 masl) pastures, it has been hypothesised that camelids were also raised at lower altitudes in the arid coastal river valleys. Previous isotopic studies of Early Intermediate Period (c. 200 BC - AD 600) and Middle Horizon (c. AD 600 - 1100) camelids support this argument. Here, we utilise carbon and nitrogen isotopic analyses of camelid bone collagen from the Early Horizon (c. 800 - 200 BC) sites of Caylán and Huambacho on …

Stable Isotopes And Selective Forces: Examples In Biocultural And Environmental Anthropology, Christine D. White, Fred J. Longstaffe

Earth Sciences Publications

No abstract provided.

Isotopic Anthropology Of Rural German Medieval Diet: Intra- And Inter-Population Variability, Karyn C. Olsen, Christine D. White, Fred J. Longstaffe, Frank J. Rühli, Christina Warinner, Domingo S. Salazar-Garcia

Earth Sciences Publications

This study investigates the diet of an 11th century CE parish community located in northwestern Germany. We assessed the isotopic compositions of human (n = 24) and faunal (n = 17) bone collagen (δ¹³C_col, δ¹⁵N_col) and human structural carbonate (δ¹³C_sc) using skeletal material recovered from the Dalheim cemetery. Traditional interpretation of the isotopic data indicates that Dalheim residents likely relied on a C₃ plant-based diet and consumed some terrestrial animal products without evidence of marine resource input in the diet. Bivariate and multivariate models used as an additional …

Maize Provisioning Of Ontario Late Woodland Turkeys: Isotopic Evidence Of Seasonal, Cultural, Spatial And Temporal Variation, Zoe Morris, Christine D. White, Lisa Hodgetts, Fred J. Longstaffe

Earth Sciences Publications

The isotopic composition (δ¹³C, δ¹⁵N) of bone collagen from Ontario Late Woodland archaeological turkeys was compared with that of modern Ontario wild turkeys, and archaeological turkeys from American Southwestern, Mexican and other Woodland sites to determine whether Late Woodland Ontario peoples managed wild turkeys by provisioning them with maize, the only isotopically distinct horticultural plant at that time. Despite the fact that humans from Late Woodland Western Basin and Iroquoian traditions consumed equal amounts of maize, wild turkeys utilized by the two groups exhibit different diets. Western Basin turkeys reflect a C₃-only diet, …

Genomic Signatures For Paclitaxel And Gemcitabine Resistance In Breast Cancer Derived By Machine Learning., Stephanie N Dorman, Katherina Baranova, Joan H M Knoll, Brad L Urquhart, Gabriella Mariani, Maria Luisa Carcangiu, Peter K Rogan

Biochemistry Publications

Increasingly, the effectiveness of adjuvant chemotherapy agents for breast cancer has been related to changes in the genomic profile of tumors. We investigated correspondence between growth inhibitory concentrations of paclitaxel and gemcitabine (GI50) and gene copy number, mutation, and expression first in breast cancer cell lines and then in patients. Genes encoding direct targets of these drugs, metabolizing enzymes, transporters, and those previously associated with chemoresistance to paclitaxel (n = 31 genes) or gemcitabine (n = 18) were analyzed. A multi-factorial, principal component analysis (MFA) indicated expression was the strongest indicator of sensitivity for paclitaxel, and copy number and expression …

Testosterone, Migration Distance, And Migratory Timing In Song Sparrows Melospiza Melodia, Alannah H. Lymburner, Tosha R. Kelly, Keith A. Hobson, Elizabeth A. Macdougall-Shackleton, Scott A. Macdougall-Shackleton

Biology Publications

In seasonally migratory animals, migration distance often varies substantially within populations such that individuals breeding at the same site may overwinter different distances from the breeding grounds. Shorter migration may allow earlier return to the breeding grounds, which may be particularly advantageous to males competing to acquire a breeding territory. However, little is known about potential mechanisms that may mediate migration distance. We investigated naturally-occurring variation in androgen levels at the time of arrival to the breeding site and its relationship to overwintering latitude in male and female song sparrows (Melospiza melodia). We used stable isotope analysis of hydrogen …

Microglia And Neurons In The Hippocampus Of Migratory Sandpipers., C G Diniz, N G M Magalhães, A A Sousa, C Santos Filho, D G Diniz, C M Lima, M A Oliveira, D C Paulo, P D C Pereira, D F Sherry, C W Picanço-Diniz

Brain and Mind Institute Researchers' Publications

The semipalmated sandpiper Calidris pusilla and the spotted sandpiper Actitis macularia are long- and short-distance migrants, respectively. C. pusilla breeds in the sub-arctic and mid-arctic tundra of Canada and Alaska and winters on the north and east coasts of South America. A. macularia breeds in a broad distribution across most of North America from the treeline to the southern United States. It winters in the southern United States, and Central and South America. The autumn migration route of C. pusilla includes a non-stop flight over the Atlantic Ocean, whereas autumn route of A. macularia is largely over land. Because of …

Medial Prefrontal And Anterior Insular Connectivity In Early Schizophrenia And Major Depressive Disorder: A Resting Functional Mri Evaluation Of Large-Scale Brain Network Models., Jacob Penner, Kristen A Ford, Reggie Taylor, Betsy Schaefer, Jean Théberge, Richard W J Neufeld, Elizabeth A Osuch, Ravi S Menon, Nagalingam Rajakumar, John M Allman, Peter C Williamson

Brain and Mind Institute Researchers' Publications

Anomalies in the medial prefrontal cortex, anterior insulae, and large-scale brain networks associated with them have been proposed to underlie the pathophysiology of schizophrenia and major depressive disorder (MDD). In this study, we examined the connectivity of the medial prefrontal cortices and anterior insulae in 24 healthy controls, 24 patients with schizophrenia, and 24 patients with MDD early in illness with seed-based resting state functional magnetic resonance imaging analysis using Statistical Probability Mapping. As hypothesized, reduced connectivity was found between the medial prefrontal cortex and the dorsal anterior cingulate cortex and other nodes associated with directed effort in patients with …

Experimental Exposure To Urban And Pink Noise Affects Brain Development And Song Learning In Zebra Finches (Taenopygia Guttata), Dominique A. Potvin, Michael T. Curcio, John P. Swaddle, Scott A. Macdougall-Shackleton

Brain and Mind Institute Researchers' Publications

Recently, numerous studies have observed changes in bird vocalizations-especially song-in urban habitats. These changes are often interpreted as adaptive, since they increase the active space of the signal in its environment. However, the proximate mechanisms driving cross-generational changes in song are still unknown. We performed a captive experiment to identify whether noise experienced during development affects song learning and the development of song-control brain regions. Zebra finches (Taeniopygia guttata) were bred while exposed, or not exposed, to recorded traffic urban noise (Study 1) or pink noise (Study 2). We recorded the songs of male offspring and compared these to fathers' …

Leisure Notes, 2014-2016, State University Of New York College At Cortland

Recreation, Parks, & Leisure

SUNY Cortland Department of Recreation, Parks, and Leisure Studies Alumni Newsletter.

Building A History Of Horizontal Gene Transfer In E. Coli, Matthew Wilber

HMC Senior Theses

Bacteria's ability to pass entire genes between one another, a process called Horizontal Gene Transfer (HGT), has a major impact on bacterial evolution. In an ongoing project at Harvey Mudd, computational methods have been used to catalogue the HGT events that have impacted a group of closely related bacteria.

This thesis builds on that project, by improving our ability to identify gene families --- groups of genes in different strains that are related. Previously, similarity was measured only by comparing two genes' DNA sequences, ignoring their positions on the organism's DNA. Here, we leverage genes' relative position to make a …