Digital Commons Network^™

Serum Amyloid A Impairs The Antiinflammatory Properties Of Hdl, Chang Yeop Han, Chongren Tang, Myriam E. Guevara, Hao Wei, Tomasz Wietecha, Baohai Shao, Savitha Subramanian, Mohamed Omer, Shari Wang, Kevin D. O'Brien, Santica M. Marcovina, Thomas N. Wight, Tomas Vaisar, Maria C. De Beer, Frederick C. De Beer, William R. Osborne, Keith B. Elkon, Alan Chait

Physiology Faculty Publications

HDL from healthy humans and lean mice inhibits palmitate-induced adipocyte inflammation; however, the effect of the inflammatory state on the functional properties of HDL on adipocytes is unknown. Here, we found that HDL from mice injected with AgNO₃ fails to inhibit palmitate-induced inflammation and reduces cholesterol efflux from 3T3-L1 adipocytes. Moreover, HDL isolated from obese mice with moderate inflammation and humans with systemic lupus erythematosus had similar effects. Since serum amyloid A (SAA) concentrations in HDL increase with inflammation, we investigated whether elevated SAA is a causal factor in HDL dysfunction. HDL from AgNO₃-injected mice lacking Saa1.1 …

The Effect Of In Vitro Cultivation On The Transcriptome Of Adult Brugia Malayi, Cristina Ballesteros, Lucienne Tritten, Maeghan O’Neill, Erica Burkman, Weam I. Zaky, Jianguo Xia, Andrew Moorhead, Steven A. Williams, Timothy G. Geary

Biological Sciences: Faculty Publications

Infections with filarial worms cause serious physical impairment and affect tens of millions of people in tropical and subtropical countries. To better understand the biology and phar- macology of these parasites, Brugia malayi is often used as a model. This parasite can be maintained in the laboratory in Mongolian jirds, enabling researchers to test drugs in vivoand in vitro, among other studies. The effects of removing worms from their hosts and cul- turing them may affect many aspects of their physiology, including response to drugs, but the extent to which the worms undergo changes during culture has remained unknown. Using …

Microbial Biofilm Community Variation In Flowing Habitats: Potential Utility As Bioindicators Of Postmortem Submersion Intervals, Jennifer M. Lang, Racheal Erb, Jennifer L. Pechal, John R. Wallace, Ryan W. Mcewan, Mark Eric Benbow

Biology Faculty Publications

Biofilms are a ubiquitous formation of microbial communities found on surfaces in aqueous environments. These structures have been investigated as biomonitoring indicators for stream heath, and here were used for the potential use in forensic sciences. Biofilm successional development has been proposed as a method to determine the postmortem submersion interval (PMSI) of remains because there are no standard methods for estimating the PMSI and biofilms are ubiquitous in aquatic habitats. We sought to compare the development of epinecrotic (biofilms on Sus scrofa domesticus carcasses) and epilithic (biofilms on unglazed ceramic tiles) communities in two small streams using bacterial automated …

State V. Holcomb Appellant's Brief Dckt. 43310

Not Reported

No abstract provided.

State V. Ashford Appellant's Brief Dckt. 43341

Not Reported

No abstract provided.

Week Of January 4, 2016, New York Medical College

InTouch

• Katharine Yamulla is Named Director of the Clinical Skills and Simulation Center
• SOM Bids Farewell to Montgomery Douglas, M.D.
• Department of Microbiology and Immunology Hosts Research Forum
• Class of 2018 Helps Spread Holiday Cheer
• NYMC Welcomes Orange-Ulster BOCES Health Occupations Students of America

Corn Era Hybrid Response To Nitrogen Fertilization, Krishna P. Woli, Matthew J. Boyer, Roger Wesley Elmore, John E. Sawyer, Lori J. Abendroth, Daniel W. Barker

Department of Agronomy and Horticulture: Faculty Publications

Corn (Zea mays L.) N use is of continued interest due to agronomic performance and environmental issues. This 2-yr study evaluated era hybrid response to fertilizer nitrogen (FN) rate in a factorial arrangement of one popular hybrid per five decades (1960–2000 eras) and five N rates (0–224 kg N ha^–1). An additional hybrid per era was grown at 168 kg N ha^–1. Hybrid productivity and nitrogen use efficiency (NUE) increased across the eras, but not between the 1980 and 1990 eras. Grain yield (GY) increased 65% and total plant biomass 43%, however, total plant nitrogen …

Lessons Learned: Feasibility Of A Discussion Prompting Tool To Increase Fertility Risk Discussion Among Adolescent Oncology Families, Devin Murphy, Caprice A. Knapp, Kelly K. Sawczyn, Susan T. Vadaparampil Ph.D, Alice Rhoton-Vlasak, Gwendolyn P. Quinn

The Qualitative Report

The purpose of this study was to explore the feasibility of distributing a prompting tool (stress egg) in order to increase discussions about fertility risk and preservation (FP) among female adolescent oncology patients, parents, and healthcare providers (HCP). 200 eggs were distributed to four pediatric oncology centers. Qualitative interviews were completed with healthcare staff (N=7) after 6 months of distribution to newly diagnosed female oncology patients ages 12-18. Interviews showed that the main barriers to distribution of the prompt were: forgetting to distribute the eggs; uncertainty about the significance of fertility; and uncertainty about fertility issues in general for female …

The Bunk House Rules: A Materialist Approach To Legal Consciousness In The Context Of Migrant Workers’ Housing In Ontario, Adrian Smith

Osgoode Hall Law Journal

In this article, I tackle the controversy surrounding an application to convert an abandoned school into housing for migrant agricultural workers in Ontario. I examine how the written reactions of community residents to a proposed municipal zoning by-law amendment convey and invoke understandings of the legal regulation of temporary labour migration. Viewed through a legal consciousness analytical lens that has been reconstituted to attend to the material practices and contexts underpinning residents’ responses (a materialist approach to legal consciousness), the submissions intervene in the organization and regulation of agricultural labour. While rehearsing well-worn, racist colonial tropes, these responses (re)produce material …

Characterization Of Fluorescent Proteins For Three- And Four-Color Live-Cell Imaging In S. Cerevisiae, Ryo Higuchi-Sanabria, Enrique J. Garcia, Delia Tomoiaga, Emilia L. Munteanu, Paul Feinstein, Liza A. Pon

Publications and Research

Saccharomyces cerevisiae are widely used for imaging fluorescently tagged protein fusions. Fluorescent proteins can easily be inserted into yeast genes at their chromosomal locus, by homologous recombination, for expression of tagged proteins at endogenous levels. This is especially useful for incorporation of multiple fluorescent protein fusions into a single strain, which can be challenging in organisms where genetic manipulation is more complex. However, the availability of optimal fluorescent protein combinations for 3-color imaging is limited. Here, we have characterized a combination of fluorescent proteins, mTFP1/mCitrine/ mCherry for multicolor live cell imaging in S. cerevisiae. This combination can be used with …

Respecting Anatomically Rigid Regions In Nonrigid Registration, Eric J. Spangler

Theses

Medical image registration has received considerable attention in the medical imaging and computer vision communities because of the variety of ways in which it can potentially improve patient care. This application of image registration aligns images of regions of the human body for comparing images of the same patient at different times, for example, when assessing differences in a disease over time; comparing images of the same anatomical structure across different patients, for example, to understand patient variability; and comparing images of the same patient from different modalities that provide complementary information, for example, CT and PET to assess cancer. …

Winter Cover Crops Impact On The Distribution Of Soil Inorganic Nitrogen And Subsequent Crop Uptake And Yield Following Fall Applied Anhydrous Ammonium, William Travis Deppe

Theses and Dissertations

The pairing of cover crops with spring application of nitrogen has shown improved nitrogen efficiency in corn production systems. However, studies have shown that only 50% of central Illinois farmers practice spring application of nitrogen. Furthermore, the literature demonstrates that in years with above average rainfall, fall applied N management systems are more susceptible to N loading relative to spring systems. Therefore, the objective of this research was to determine the efficacy of winter cover crops to impact the distribution of soil inorganic N following fall applied anhydrous ammonium. The experimental site is located at the Illinois State University Research …

Integrative Analysis Of Breast Cancer Reveals Prognostic Haematopoietic Activity And Patient-Specific Immune Response Profiles, Frederick S. Varn, Erik H. Andrews, David W. Mullins, Chao Cheng

Dartmouth Scholarship

Transcriptional programmes active in haematopoietic cells enable a variety of functions including dedifferentiation, innate immunity and adaptive immunity. Understanding how these programmes function in the context of cancer can provide valuable insights into host immune response, cancer severity and potential therapy response. Here we present a method that uses the transcriptomes of over 200 murine haematopoietic cells, to infer the lineage-specific haematopoietic activity present in human breast tumours. Correlating this activity with patient survival and tumour purity reveals that the transcriptional programmes of many cell types influence patient prognosis and are found in environments of high lymphocytic infiltration. Collectively, these …

Effects Of Soybean Meal Substitution For Fish Meal In Diets Of Juvenile Bluegill (Lepomis Macrochrius), K. Stuckenschneider, A. Allen, A. Weckenborg, Gregory A. Dudenhoeffer

Cooperative Extension Research Publications

Bluegill has potential for production as a food fish. Feed is 40-60% of total production costs. Few studies have been conducted on bluegill replacing fish meal with soybean meal, which is a less expensive plant protein source. The objective of this experiment was to determine the effect of 25, 50, 75% soybean meal substitution of fish meal protein in juvenile bluegill diets. Treatments consisted of a 38% crude protein control diet, and diets with 25, 50, and 75% of fish meal replaced with soybean meal (SB Sub). All diets were insonitrogenous and isocaloric. A completely randomized block design was used …

04. Botany, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

How Do Teachers And Students Perceive The Utility Of Blackboard As A Distance Learning Platform? (Case Study From Taibah University, Saudi Arabia), Suad Alaofi

Dissertations

This research explores the role of Knowledge Management within the education field with a specific focus on the use of Learning Management Systems in the Distance Learning (e-learning) process. The aim of this study is to thoroughly examine how teachers and students perceive the utility of the Blackboard system as a distance learning platform. To achieve this, the study conducted qualitative interviews and quantitative questionnaire surveys with the teachers and students of Taibah University, Saudi Arabia. Questions in both data collection tools were geared towards gaining insight about how these two groups of Blackboard users view its usefulness as a …

Denitrification As A Source Of Nitric Oxide Emissions From Incubated Soil Cores From A Uk Grassland, N Loick, Er Dixon, D Abalos, A Vallejo, Gp Matthews, Kl Mcgeough, R Well, C Watson, Rj Laughlin, Lm Cardenas

School of Geography, Earth and Environmental Sciences

Agricultural soils are a major source of nitric oxide (NO) and nitrous oxide (N2O), which are produced and consumed by biotic and abiotic soil processes. The dominant sources of NO and N2O are microbial nitrification and denitrification. While N2O emissions have been attributed to both processes, depending on the environmental conditions such as substrate availability, pH and water filled pore space (WFPS), NO emissions are thought to predominantly derive from nitrification. Although attributing gaseous emissions to specific processes is still difficult, recent findings challenge the latter of those assumptions. Using the gas-flow-soil-core method, i.e soil cores incubated under a He/O2 …

Ancient Animal Ethics: The Earliest Arguments For The Ethical Consideration Of Nonhuman Animals, Joshua J. Sias

The Downtown Review: An Interdisciplinary Journal Written and Peer-Reviewed by Mandel Honors College Students at Cleveland State University

Primarily focused on the ancient Greek philosophers, this work offers a survey of the earliest arguments for and against the inclusion of nonhuman animals in human realms of ethical consideration. By following the trends of ancient western thought concerning animal ethics, the influencing factors behind the downfall of the subject in Medieval times, both in terms of discourse and practice, is discovered in the philosophical exchange that preceded medieval thought.

Antecedents Of Cross-Cultural Adaptation Stress In Short-Term International Assignments, Kerri Anne Crowne, Robert L. Engle

Organization Management Journal

This study examines the role of cultural intelligence, perceived language fluency, and number of previous international experiences during a short-term international community service project in a foreign country. Based on a sample of 171 undergraduate and graduate students, the findings suggest that motivational cultural intelligence significantly impacted lowering cross-cultural adaptation stress levels experiences during short-term trips, while perceived language ability significantly increased stress levels. In addition, the control variables of age and gender were also found to significantly impact stress levels. Implications for research and practice are discussed

03. Biology, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

Limiting The Impact Of Destructive Analytical Techniques Through Sequential Microspatial Sampling Of The Enamel From Single Teeth, Alexis E. Dolphin, Mathew A. Teeter, Christine D. White, Fred J. Longstaffe

Earth Sciences Publications

A fundamental research concern within contemporary bioarchaeology is the sensitive balance between the preservation of human remains and the use of destructive techniques to collect information. Here we describe one example of how multiple microspatial destructive/semi-destructive techniques may be carried out in sequence using only the enamel of a single tooth. With careful planning of both sample preparation strategies and sequencing of sampling methods, it is possible to produce multiple datasets, and yet to retain material for future analyses.

In this case, enamel from the teeth of 27 individuals who lived during the early medieval period (AD 1170-1198) in Bergen, …

Attitudes And Beliefs About Mental Illness Among Church-Based Lay Health Workers: Experience From A Prevention Of Mother-To-Child Hiv Transmission Trial In Nigeria, Theedeus Iheanacho, Daniel Kapadia, Chinenye O. Ezeanolue, Alice A. Osuji, Amaka G. Ogidi, Anulika Ike, Dina Patel Elina, Elina Stefanovics, Robert Rosenheck, Michael Obiefune Echezona, Echezona E. Ezeanolue

Environmental & Global Health Faculty Research

Common mental disorders are prevalent in Nigeria. Due to stigma and a limited number of trained specialists, only 10% of adults with mental illness in Nigeria receive any care. The Healthy Beginning Initiative is a community-based maternal/child health program that includes screening for perinatal depression and was implemented by lay, volunteer, church-based health advisors (CHAs). The aim of the study was to assess the beliefs and attitudes about mental illness among the CHAs. The study used a cross-sectional survey of 57 CHAs, who completed a 43-item, self-administered questionnaire that assessed their beliefs and attitudes about mental illness. The response rate …

Atypical Visual And Somatosensory Adaptation In Schizophrenia-Spectrum Disorders, Gizely Andrade, John Butler, Gregory Peter, Sophie Molholm, John J. Foxe

Articles

Neurophysiological investigations in patients with schizophrenia consistently show early sensory processing deficits in the visual system. Importantly, comparable sensory deficits have also been established in healthy first-degree biological relatives of patients with schizophrenia and in first-episode drug-naive patients. The clear implication is that these measures are endophenotypic, related to the underlying genetic liability for schizophrenia. However, there is significant overlap between patient response distributions and those of healthy individuals without affected first-degree relatives. Here we sought to develop more sensitive measures of sensory dysfunction in this population, with an eye to establishing endophenotypic markers with better predictive capabilities. We used …

High School General Education Teachers' Perception Of Iep Accommodations For Students With Asperger Syndrome, Mary Patricia Krones

Theses and Dissertations

The purpose of this qualitative design study was to better understand the experiences of high school general education English teachers who have students with Asperger Syndrome in their classes. More specifically, this researcher wanted to better understand the teacher's perception of the IEP-denoted accommodations the general education teachers are responsible for implementing. Data collection consisted of semi-structured interviews, classroom observations, journal entries and collection of artifacts. Findings of this study include: the IEP document and IEP process from the lens of the general education teacher do not provide adequate information when considering the unique needs of students with Asperger Syndrome; …

Self-Disseminating Vaccines For Emerging Infectious Diseases, Aisling A. Murphy, Alec J. Redwood, Michael A. Jarvis

School of Biomedical Sciences

No abstract provided.

Ocular Drift Along The Mental Number Line., A Myachykov, R Ellis, A Cangelosi, Mh Fischer

School of Psychology

We examined the spontaneous association between numbers and space by documenting attention deployment and the time course of associated spatial-numerical mapping with and without overt oculomotor responses. In Experiment 1, participants maintained central fixation while listening to number names. In Experiment 2, they made horizontal target-direct saccades following auditory number presentation. In both experiments, we continuously measured spontaneous ocular drift in horizontal space during and after number presentation. Experiment 2 also measured visual-probe-directed saccades following number presentation. Reliable ocular drift congruent with a horizontal mental number line emerged during and after number presentation in both experiments. Our results provide new …

A Photoactivatable Src Homology 2 (Sh2) Domain, X. Song, X. Shang, T. Ju, Ronald Cerny, Wei Niu, Jiantao Guo

Ronald Cerny Publications

Src homology 2 (SH2) domains bind specifically to phosphotyrosine-containing motifs. As a regulatory module of intracellular signaling cascades, the SH2 domain plays important roles in the signal transduction of receptor tyrosine kinase pathways. In this work, we reported the construction of a photoactivatable SH2 domain through the combination of protein engineering and genetic incorporation of photo-caged unnatural amino acids. Significantly enhanced recognition of a phosphotyrosine-containing peptide substrate by the engineered SH2 domain mutant was observed after light-induced removal of the photo-caging group. Optical activation allows the control of protein and/or cellular function with temporal and spatial resolution. This photoactivatable SH2 …

Hunting Down Pigs, Anna-Lisa Astudillo

Electronic Theses and Dissertations

Hunting Down Pigs is a hybrid collection of personal essays, ranging from lyrical to braided, which more often than not defy labeling. The essays explore themes of loss, faith, and self-reliance. Growing up Mormon, with all its strictures, and losing her dad at a young age, made faith an issue that the narrator grappled with continuously throughout her life. The narrator questions the validity and purpose of religion in essays like "Possibilities" and "Going to Church." Specifically, the narrator explores the doctrine of the Mormon church and the effects of such a strict upbringing. When divine intervention fails, the narrator …

Dry Edible Bean Disease Diagnostic Series, Samuel G. Markell, Robert M. Harveson, Julie Pasche

Department of Plant Pathology: Faculty Publications

Root Diseases

Fusarium root rot...................................PP1820-1

Pythium diseases..................................PP1820-2

Rhizoctonia root rot...............................PP1820-3

Soybean cyst nematode (SCN).............PP1820-4

Soybean cyst nematode sampling.........PP1820-5

Stem and Wilt Diseases

Bacterial wilt..........................................PP1820-6

Fusarium yellows (wilt)..........................PP1820-7

Stem rot.................................................PP1820-8

White mold.............................................PP1820-9

Foliar Diseases

Anthracnose........................................PP1820-10

Bacterial brown spot............................PP1820-11

Bean common mosaic virus................PP1820-12

Common bean rust..............................PP1820-13

Common bacterial blight .....................PP1820-14

Halo blight............................................PP1820-15

Fungicide Application Timing With Effects On Grey Leaf Spot And Southern Rust In Nebraska Field Corn, 2015, J. D. Harbour, T. A. Jackson-Ziems

Department of Plant Pathology: Faculty Publications

The objective of the trial was to compare foliar fungicides applied to three growth stages of corn for grey leaf spot (GLS) and southern rust (SR) efficacy. Irrigated corn was grown based on Nebraska Extension irrigation recommendations at the South Central Ag Lab near Clay Center, NE. Soils were a silt loam with 6.7 pH and 1.8% OM and the previous crop was soybean. Reduced tillage was performed to the field prior to planting. Corn (DKC 65-79 RIB, tolerant to gray leaf spot) was planted at approximately 34,000 seed/A on 26 May. Eight treatments were arranged in a randomized complete …