Digital Commons Network^™

Automated Assessment Of Disease Progression In Acute Myeloid Leukemia By Probabilistic Analysis Of Flow Cytometry Data, Bartek Rajwa, Paul K. Wallace, Elizabeth A. Griffiths, Murat Dundar

Bindley Publications

Objective: Flow cytometry (FC) is a widely acknowledged technology in diagnosis of acute myeloid leukemia (AML) and has been indispensable in determining progression of the disease. Although FC plays a key role as a post-therapy prognosticator and evaluator of therapeutic efficacy, the manual analysis of cytometry data is a barrier to optimization of reproducibility and objectivity. This study investigates the utility of our recently introduced non-parametric Bayesian framework in accurately predicting the direction of change in disease progression in AML patients using FC data. Methods: The highly flexible non-parametric Bayesian model based on the infinite mixture of infinite Gaussian …

Volume Cxxxiii, Number 10, January 15, 2016, Lawrence University

The Lawrentian

No abstract provided.

The Modulation Of Adiponectin By Stat5-Activating Hormones, Ursula A. White, Joel Maier, Peng Zhao, Allison J. Richard, Jacqueline M. Stephens

Faculty Publications

© 2016 the American Physiological Society. Adiponectin is a hormone secreted from adipocytes that plays an important role in insulin sensitivity and protects against metabolic syndrome. Growth hormone (GH) and prolactin (PRL) are potent STAT5 activators that regulate the expression of several genes in adipocytes. Studies have shown that the secretion of adiponectin from adipose tissue is decreased by treatment with PRL and GH. In this study, we demonstrate that 3T3-L1 adipocytes treated with GH or PRL exhibit a reduction in adiponectin protein levels. Furthermore, we identified three putative STAT5 binding sites in the murine adiponectin promoter and show that …

Examination Of Commercially Available Copper Oxide Wire Particles In Combination With Albendazole For Control Of Gastrointestinal Nematodes In Lambs, J. M. Burke, J. E. Miller, T. H. Terrill, E. Smyth, M. Acharya

Faculty Publications

© 2015 Published by Elsevier B.V. Control of gastrointestinal nematodes (GIN) remains a critical issue due to the prevalence of anthelmintic resistance. The objective of the experiment was to determine the efficacy of copper oxide wire particles (COWP) from three commercial sources and a combination of COWP and albendazole to control GIN and/or Haemonchus contortus in lambs. Naturally infected Katahdin lambs in early June 2014 and 2015 were randomly assigned to receive no COWP (CON; n = 9 and 12) or 2 g COWP in a gel capsule as Copasure® (COP; n = 4 and 17; Animax Ltd.), copper oxide-wire …

Vaccines And The Looming Threat Of Syphilis, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

During the past several decades, syphilis has increased in the US and explosively so in China and Russia.While most current cases can be cured by penicillin or second line antibiotics, strains of the syphilis spirochete (Treponema pallidum) resistant to the latter have emerged.And the potential of strains to acquire resistance to penicillin via plasmids has recently been recognized.The 36 million-plus undertreated cases of syphilis in the world represent metaphorically a vast global 37°C incubator allowing exchange of antibiotic resistant genes among the human-borne bacteria and theoretically permitting the emergence of penicillin resistant strains.None has yet been identified but …

Student See Versus Student Do: A Comparative Study Of Two Online Tutorials, Ilana Stonebraker, M Brooke Robertshaw, Jennifer D. Moss

Libraries Faculty and Staff Scholarship and Research

This study examines the impact on student performance after interactive and non-interactive tutorials using a 2 × 2 treatment-control design. In an undergraduate management course, a control group watched a video tutorial while the treatment group received the same content using a dynamic tutorial. Both groups received the same quiz questions. Using effect size to determine magnitude of change, it was found that those in the treatment condition performed better than those in the control condition. Students were able to take the quiz up to two times. When examining for change in performance from attempt one to attempt two, the …

January 15, 2016, The Dakota Student

The Dakota Student

No abstract provided.

The Future Of Work: Apps, Artificial Intelligence, Automation And Androids, David R. Barnhizer

Law Faculty Articles and Essays

The analysis offered here is not a Neo-Luddite rage against “the machine.” As with the oft-stated reproach about paranoia, there sometimes really are situations in which people are “out to get you.” In our current situation the threat is not from people but from the convergence of a set of technological innovations that are and will increasingly have an enormous impact on the nature of work, economic and social inequality and the existence of the middle classes that are so vital to the durability of Western democracy. The fact is that developed nations’ economies such as found in Western Europe …

'Fire Away': I Have No Right To Not Be Insulted, David R. Barnhizer

Law Faculty Articles and Essays

Universities are the institutions responsible for advancing our freedom of thought and discourse through the work of independent scholars and the teaching of each generation of students. But for several decades, universities and other educational institutions have increasingly set up rules aimed at protecting individuals and groups from criticism that those individuals and groups consider insensitive, offensive, harassing, intolerant and disrespectful, critical of their core belief systems or threats to their agendas. Even though it has been claimed that disadvantaged interest groups have a right to use one-sided tactics of intolerance against those they consider to be responsible for their …

Academic Supply And Occupational Demand In Tennessee Annual Report 2016, Tennessee. Higher Education Commission.

Academic Programs and Workforce Reports

No abstract provided.

The Pseudorabies Virus Protein, Pul56, Enhances Virus Dissemination And Virulence But Is Dispensable For Axonal Transport, Gina R. Daniel, Patricia J. Sollars, Gary E. Pickard, Gregory A. Smith

School of Veterinary and Biomedical Sciences: Faculty Publications

Neurotropic herpesviruses exit the peripheral nervous system and return to exposed body surfaces following reactivation from latency. The pUS9 protein is a critical viral effector of the anterograde axonal transport that underlies this process. We recently reported that while pUS9 increases the frequency of sorting of newly assembled pseudorabies virus particles to axons from the neural soma during egress, subsequent axonal transport of individual virus particles occurs with wild-type kinetics in the absence of the protein. Here, we examine the role of a related pseudorabies virus protein, pUL56, during neuronal infection. The findings indicate that pUL56 is a virulence factor …

The Essential Elements Of Adolescent-Friendly Care In School-Based Health Centers: A Mixed Methods Study Of The Perspectives Of Nurse Practitioners And Adolescents, Alison Moriarty Daley

Doctoral Dissertations

The Essential Elements of Adolescent-Friendly Care in School-Based Health Centers: A Mixed Methods Study of the Perspectives of Nurse Practitioners and Adolescents

Alison Moriarty Daley Ph.D.

University of Connecticut, 2016

The majority of the morbidity and mortality among adolescents results from preventable causes including risk-taking behaviors and injuries. Preventive care for this population therefore includes anticipatory guidance and screening aimed at reducing these risks. However, the rates of engagement in preventive care decline steadily throughout adolescence. School-based health centers (SBHCs) have been identified as an adolescent-friendly community resource for preventive care. The purpose of this study was to identify the …

Plant Microfossils Recovered From Dental Calculus At Casas Grandes, Mexico, Daniel King, Michael T. Searcy, Kyle Waller

Faculty Publications

Microfossil analysis is a technique used to better understand prehistoric diets. As part of a larger multinational project, we gathered and analyzed 112 samples of dental calculus (fossilized plaque) from human remains discovered at Paquimé and other sites in the Casas Grandes river valley to identify various microfossils still present in the silica matrix. With this information, we are able to better understand the flora present during ancient times and how it was used (food, processing, etc.).

Hb 568 – Domestic Relations: Determination Of Paternity

Georgia State University Law Review

No abstract provided.

Food Insecurity And Cardiovascular Risk Factors In U.S. Adolescents, Elisabeth L P Sattler, Vibha Bhargava

Journal of Applied Research on Children: Informing Policy for Children at Risk

Introduction: Disparities in cardiovascular diseases are one of today’s most important public health challenges. Pathological processes related to modifiable cardiovascular risk factors have shown to begin in childhood and disparities in these risk factors have been reported in adolescence. Food insecurity is significantly associated with cardiovascular risk factors in adults; however, little is known about cardiovascular risk in food insecure adolescents.

Objective: The objective of this study was to examine the relationship between food insecurity and cardiovascular risk factors in U.S. adolescents aged 12-17 years.

Methods: Using cross-sectional data on 1,853 adolescents aged 12-17 years from the National Health and …

A New Species Of The Genus Thaicharmus Kovařík, 1995 (Scorpiones: Buthidae) From Northeast India, Zeeshan A. Mirza, Rajesh V. Sanap, Krushnamegh Kunte

Euscorpius

A new species Thaicharmus guptai sp. nov. is described from the northeast Indian state of Tripura. The new species differs from the known members of the genus in the following set of morphological characters: large size (total length 45.6 mm); trichobothrium d₂ is distal to i₁ on femur; trichobothria est, em and et on the external surface of the patella do not form a straight line. Subaculear tubercle is absent. The movable finger of pedipalp chela has 12 cutting rows of denticles. The movable finger is much longer than the pedipalp patella. Number of pectinal teeth 20/19; pectines …

Pseudouroctonus Peccatum Tate Et Al., 2013, Rediscovered, Richard F. Ayrey

Euscorpius

Shortly after the discovery of Pseudouroctonus peccatum Tate, Riddle, Soleglad et Graham, 2013 (Scorpiones: Vaejovidae) there was a large wildfire in the Spring Mountains of Nevada. At the time the species description was published, it was noted that the only known population of this species may have been extirpated by the fire and subsequent flooding of the type locality habitat (Tate et al. 2013). Today it is certain that the species has survived after the collection of 12 new specimens. Additional data on males are also presented.

The Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for January 14-20, 2016. Vol. 102, No. 1.

Permanent Draft Genome Sequences For Two Variants Of Frankia Sp. Strain Cpi1, The First Frankia Strain Isolated From Root Nodules Of Comptonia Peregrina, Rediet Oshone, Sheldon G. Hurst Iv, Feseha Abebe-Akele, Stephen Simpson, Krystalynne Morris, W. Kelley Thomas, Louis S. Tisa

Molecular, Cellular & Biomedical Sciences

Frankia stains CpI1-S and CpI1-P are members of Frankia lineage Ia that are able to reinfect plants of the Betulaceae and Myricaceae families. Here, we report two 7.6-Mbp draft genome sequences with 6,396 and 6,373 candidate protein-coding genes for CpI1-S and CpI1-P, respectively.

Permanent Draft Genome Sequences For Two Variants Of Frankia Sp. Strain Cpi1, The First Frankia Strain Isolated From Root Nodules Of Comptonia Peregrina, Rediet Oshone, Sheldon G. Hurst Iv, Feseha Abebe-Akele, Stephen D. Simpson, Krystalynne Morris, William Kelley Thomas, Louis S. Tisa

New Hampshire Agricultural Experiment Station Publications

Frankia stains CpI1-S and CpI1-P are members of Frankia lineage Ia that are able to reinfect plants of the Betulaceae and Myricaceae families. Here, we report two 7.6-Mbp draft genome sequences with 6,396 and 6,373 candidate protein-coding genes for CpI1-S and CpI1-P, respectively.

The Setonian, January 14, 2016, Seton Hall University

2016

No abstract provided.

Cancer Genomics And Biology 2015 – Meeting Report, Louis W.C. Chow, Luis Costa, Bin-Tean Teh, Da-Qiang Li, Gu Feng, Rakesh Kumar, +10 Additional Authors

Biochemistry and Molecular Medicine Faculty Publications

The Cancer Genomics and Biology 2015 meeting embodied a three way collaboration among colleagues from the Global Cancer Genomics Consortium (GCGC), the Unifaith Cancer Institute China and Jiujiang University of China. The meeting marks the fifth and the last meeting of GCGC, which was formed in 2010. Previous four GCGC meetings have been held at the Tata Memorial Center- Mumbai, Institute of Molecular Medicine-Lisbon, and Graduate Medical School Kyoto University-Kyoto. In contrast to the genomic themes of the previous meetings, the 2015 conference theme was at the interface of laboratory and translation research and emerging therapeutics as reflected in the …

Teams In Cancer Care, Stephen Taplin

Health Workforce Speaker Series

No abstract provided.

Curriculum Subcommittee Minutes, January 14, 2016, Utah State University

Educational Policies Committee

Semester Course Approval Reviews

Program Proposals

• Restructuring the current specialization within the Psychology PhD program in Professional Scientific Psychology to two separate specializations 1) combined Clinical/Counseling Psychology and 2) School Psychology
• Utilizing the existing MEd degree in Psychology but with a specialization as an en route degree for students in the School Psychology EdS program
• Suspending admissions in the Master of Science in Bioregional Planning
• Renaming the Master of Science and PhD in Human Dimensions of Ecosystem Science and Management to Environment and Society
• Discontinuing the Bachelor of Science degree in Geography Teaching

Other

• Syllabus task force update
• Curriculog reflections

Series Of Aging Seminars Launches At Uab, Staff

Browse All News

No abstract provided.

Effect Of Hydroxychloroquine And Characterization Of Autophagy In A Mouse Model Of Endometriosis, A. Ruiz, S. Rockfield, N. Taran, E. Haller, Robert Engelman, I Flores, P Panina-Bordignon, Meera Nanjundan

Molecular Biosciences Faculty Publications

In endometriosis, the increased survival potential of shed endometrial cells (which normally undergo anoikis) is suggested to promote lesion development. One mechanism that may alter anoikis is autophagy. Using an autophagic flux inhibitor hydroxychloroquine (HCQ), we identified that it reduces the in vitro survival capacity of human endometriotic and endometrial T-HESC cells. We also identified that HCQ could decrease lesion numbers and disrupt lesion histopathology, as well as increase the levels of peritoneal macrophages and the IP-10 (10 kDa interferon-γ-induced protein) chemokine in a mouse model of endometriosis. We noted that RNA levels of a subset of autophagic …

Targeting Wnt/Β-Catenin Pathway In Hepatocellular Carcinoma Treatment, Valery Vilchez, Lilia M. Turcios, Francesc Marti, Roberto Gedaly

Surgery Faculty Publications

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Liver cancer is generally related to hepatitis B or C infection and cirrhosis. Usually, patients with HCC are asymptomatic and are diagnosed at late stages when surgical treatment is no longer suitable. Limited treatment options for patients with advanced HCC are a major concern. Therefore, there is an urge for finding novel therapies to treat HCC. Liver cancer is highly heterogeneous and involved deregulation of several signaling pathways. Wnt/β-catenin pathway is frequently upregulated in HCC and it is implicated in maintenance of tumor initiating cells, drug …

Educational Policies Committee Agenda, January 14, 2016, Utah State University

Educational Policies Committee

• Subcommittee Reports
• Curriculum Subcommittee
• Course Approvals
• Program Proposals
• Academic Standards Subcommittee
• General Educations Subcommittee

Educational Policies Committee Minutes, January 14, 2016, Utah State University

Educational Policies Committee

• Subcommittee Reports
• Curriculum Subcommittee
• Course Approvals
• Program Proposals
• Academic Standards Subcommittee
• General Education Subcommittee

January 14, 2016, University Of North Dakota

University Senate Meeting Minutes

Minutes from the January 14, 2016, meeting of the University Senate. 18 pages