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The Grizzly, January 28, 2016, Brian Thomas, Deana Harley, Jay Farrell, Chi-E Low, Yuqing Liu, Valerie Osborne, Sarah Hojsak, Berett C. Babrich, Sean Campbell, Johnny Cope, Hunter Gellman

Ursinus College Grizzly Newspaper, 1978 to Present

Student Raises Funds to Prevent Suicide • Tragedy Prompts Main Street Changes • Ursinus Introduces Open Access Publishing System • Ursinus Welcomes Alumni as Entrepreneur-in-Residence • International Perspective: Differences in Friendships Across Cultures • "Rare Bird" Exhibit Migrates to Berman • Coasting Through Costa Rica • Opinions: Everyone's an Activist on Facebook; Letter from an Alumnus: Guns; Film Review: "Star Wars: The Force Awakens" Rates 7 / 10 • Women's Indoor Track and Field Ready to Run • Vaulting Into Action

The Bg News January 28, 2016, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 28, 2016. Volume 95-Issue 39.

The Alestle - Vol. 68. No. 19 - 01/28/2016, Southern Illinois University Edwardsville

The Alestle

Vol. 67. No. 19

Antimetabolite Ttl-315 Selectively Kills Glucose-Deprived Cancer Cells And Enhances Responses To Cytotoxic Chemotherapy In Preclinical Models Of Cancer., James Duhadaway, George C Prendergast

Kimmel Cancer Center Faculty Papers

Maintaining thiol homeostasis is an imperative for cancer cell survival in the nutrient-deprived microenvironment of solid tumors. Despite this metabolic vulnerability, a selective approach has yet to be developed to disrupt thiol homeostasis in solid tumors for therapeutic purposes. In this study, we report the identification of 2-mercaptopropionyl glycine disulfide (TTL-315) as a novel antimetabolite that blocks cell survival in a manner conditional on glucose deprivation. In the presence of glucose, TTL-315 lacks cytotoxic effects in normal cells where it is detoxified by reduction to 2-mercaptopropionyl glycine, a compound with known clinical pharmacologic and safety profiles. In several rodent models …

Response Surface Methodology Optimization Of Fermentation Conditions For Neutral Protease Production By Bacillus Cereus, Xie Wancui, Yang Yadong, Yang Xihong, Wu Shuai, Ji Hongwu

Food and Machinery

In order to improve the production of protease from Bacillus cereus, the fermentation medium composition and culture conditions were optimized. By single factor experiment, the effects were studied, including the optimum additions of carbon and nitrogen sources, the adding amounts, fermentation temperature, inoculation age, shaking speed, medium volume, medium initial pH, fermentation time, and inoculation amount on protease production. On this basis, Plackett-Burman was to evaluate the effects of nine variables, and selected significant factors, namely peptone addition amount, fermentation temperature and medium volume. The optimal fermentation condition was obtained by Box-Behnken and response surface analysis. The optimal conditions of …

Illinois Wesleyan Physics Major Presents Research At Harvard Conference, Kim Hill

News and Events (Discontinued Series)

No abstract provided.

Effect Of Branch-Chain Elongation On Physicochemical Properties And Digestibility Characterization Of Waxy Corn Starch, He Jian, Wang Ren, Zhang Hao, Zhou Xing, Chen Zhengxing

Food and Machinery

Waxy corn starch (WCS) was modified by amylosucrase (AS). The effect of starch elongation degree on the digestibility and physicochemical properties of modified waxy corn starch (WCS) was investigated. The results showed that under the given reaction condition, enzymatic reaction could be fitted by a logarithmic mathematical model. Compared with native starch, the modified WCSs expressed a continuous matrix structure, and the packing arrangement of crystalline converted from A-type into B-type. With transglycosylation rate (TR) increasing, an increased tendency of proportion of Fr I (DP＞30) was observed, whereas the contents of Fr III (DP＜13) was significantly decreased. In vitro test …

Effect Of Hot Air Drying Dehydration And Artificial Inoculation On Quality Of Kohlrabi Product, Tang Renyong, Guo Xiulan, Liu Dayu, Xie Zhenjian, Wang Chao

Food and Machinery

Aimed to perfect modern fermentation technology of Kohlrabi, and the effects were investigated, of natural wind dehydration, hot air drying dehydration and hot air drying dehydration combined artificial inoculation, on the sense score, physical and chemical index and color of Kohlrabi fermentation product. The results indicated that: 50 ℃ was the optical temperature of hot air drying dehydration; Kohlrabi product with hot air drying dehydration had white color, deficient flavor and taste of typical Kohlrabi fermented, lower sense score, amino nitrogen and lactic acid contents compared with the product with natural wind dehydration. Kohlrabi product with hot air drying dehydration …

Research On Vinegar Brand Traceability Based On Near Infrared Spectrum Technology Combined With Support Vector Machine, Liu Jing, Guan Xiao, Yi Cuiping

Food and Machinery

Presented a fast and non-destructive method for the discrimination of vinegar brands by near-infrared spectroscopy technology. One hundred and fifty-two representative samples of vinegar including Bao Ning, East Lake, Heng Shun, Zhenjiang were collected from market. Multiplicative Scatter Correction (MSC) was used to handle the original near infrared spectrum (NIR) data and Principal Component Analysis (PCA) was used to process the spectral data after pretreatment according to the accumulative contribution rate of principal components to select principal components. Support Vector Machine (SVM) was then applied to build the brand traceability model with proper kernel function. Particle Swarm Optimization was applied …

Determination Of Diethylstilbestrol In Microbial Degradation Systems By Hplc—Uv, Deng Weiqin, Li Ashuang, Peng Xian, Liu Shuangshuang, Hu Kaidi, Zhang Mengmei, He Li, Chen Shujuan, Han Xinfeng, Liu Shuliang

Food and Machinery

The concentration of diethylstilbestrol (DES) in the microbial degradation systems was determined using HPLC—UV. Different extraction methods were used in the fungi and bacteria fermentation systems, DES was separated through a Sepax GP-C₁₈ (150 mm×4.60 mm, 5.0 μm), eluted with methanol-water (7︰3, V/V) at 0.7 mL/min, and detected at 242 nm. Results showed that retention time of DES was 7.714 min. Good linearity was obtained with the detection limits of 0.5～50.0 mg/L with a correlation coeffcient of 0.996 3. The average spike recovers of DES for bacteria and fungi fermentation systems were 94.04% and 95.24%, respectively, with RSD of …

Optimization On Tea Carding Technology By Artificial Neural Network, Wang Xiaoyong, Li Bing, Zeng Chen, Li Shangqing, Wu Xiankun

Food and Machinery

The influences were studied. from tea carding temperature, tea carding time and the amount of leaves on the processing, taking Lu'an green tea as material. Based on the single factor experiment, the optimum parameters were selected. The optimum parameters were as followed: carding temperature 90 ℃, carding time 5 min, and the amount of leaves 1.0 kg. Experimental data were subjected to multivariate first-order regression and multivariate quadratic regression, and two regressing equations were obtained. A neural network model based on the orthogonal experiment data was established to obtain the optimum parameters, final result for temperature at 93 ℃, tea …

Design Of A New Continuous Grading Litchi Peeling Machine, Yang Xiaotong, Duan Xu, Guo Guixia, Ren Guangyue

Food and Machinery

Based on the litchi fruit's physical and chemical properties, a new continuous fruit peeling equipment had been designed to combine the grade and peel unit. The device integrates photoelectric beam machine into the grading unit, which makes litchi fruit peeling easily after rating. The peeling mechanism is that the graded fruit cut a small opening firstly, then torn the peel. Thus the equipment could continuously finish fruit rating, orderly loading, cutting, peeling and fruit collection. Therefore, it could achieve not only achieve the high efficient rating and peeling operation, but also keep the litchi fruit integrity, which is beneficial to …

Screening Of Strain With Antioxidation Activity From Wild Macrofungi And Optimization On Its Fermentation Conditions, Chai Xinyi, Yu Shijun, Zhang Weiwei, Du Zehu

Food and Machinery

The objectives of the study were to screen the strain with a good antioxidation activity from 10 species of wild macrofungi and optimize the optimal conditions for antioxidant substance production. These results can provide some references for the breeding of Auricuiaria auricular and industrialization of its production. As material with 10 strains of wild fungi from the Langyashan in Anhui province, the strains with antioxidant substance producing were obtained by DPPH free radical scavenging rate of the broth. Shake flask culture was then used to get the optimum culture conditions based on the single factor and orthogonal experiments, which is …

Optimization Of Ultrasound/Microwave Assisted Extraction (Umae) Of Flavones From Vaccinium Bracteatum Thunb Leaves, Chen Yiyong, Zhang Dejin

Food and Machinery

Vaccinium Bracteatum Thunb Leaves (VBTL) was used as material. An efficient ultrasound/microwave assisted extraction (UMAE) technique was employed to extract flavones from VBTL. The effects of microwave power, ratio of solvent to solid, temperature and time on the yield of flavones from VBTL were investigated. To optimize the extraction process, response surface methodology was used based on the results of single factor experiment. IR spectrum was scanned to validate the effect of UMAE technology compared with the traditional solvent extraction technology. The results indicated the optimal conditions of UMAE were 140 W of microwave power, 50 W of ultrasound power, …

Study On Ultrasonic Wave-Assisted Extraction Of Active Substances From Antrodia Camphorata, Guo Danzhao, Zheng Wei, Ma Haile, Peng Ying, Liu Renkang, Liu Bei

Food and Machinery

Ultrasonic wave-assisted extraction of Antrodia camphorata's mycelim was studied. Four test factors of solid-to-liquid ratio, ultrasonic power, extraction temperature and extraction time were studied in extraction of polysaccharide and triterpenoids from Antrodia camphorata. Ultraviolet-visible spectrophotometer was used as determining method. The results showed that the extraction quantity of polysaccharide was 26.319 mg/g with 120 W ultrasonic power lasting for 35 min, under 55 ℃ with the solid-to-liquid ratio of 1︰30 (m︰V). The extraction quantity of triterpenoids was 38.624 mg/g under the optimal extraction condition which involves solid-to-liquid ratio of 1︰30 (m︰V), ultrasonic power of 210 W, extraction temperature of 50 …

Effect Of Hot Air Drying Temperature On Qualities Of Sweet Potato Powder, Guo Ting, Chen Zhenlin, He Xinyi, Xie Dongdi, Huang Huiling

Food and Machinery

In order to investigate the temperature on the quality of sweet potato powder by hot air drying, the color, rehydration capacity, particle size, viscosity, bulk density, reducing sugar and amylum of the sweet potato powder were compared. Results showed that hot air drying temperature had a significantly influence on the rehydration, particle size, viscosity and amylum of sweet potato powder (P<0.05). With the drying temperature rising, the dry basis moisture content decreased faster, the drying time shortened and amylum content increased. The sweet potato powder particle size prepared at hot air drying in 80 ℃ was the minimum, and the rehydration was the highest with good color.

Antitumor And Antiangiogenic Effects Of Flavonoids, Li Xiangzhou, Luan Fangfei, Zhang Sheng, Huang Dan

Food and Machinery

Flavonoids drugs are effective, natural, and their toxic and side effect are relatively mild. Otherwise, they have many kinds of biological effects such as anti-inflammatory, anti-bacterial, reducing blood fat, anti-aging and so on.The treatment of malignant tumor is difficult to conquer in the medical community. The majority of clinical antitumor drugs have side effects. This paper elaborated the research progress of anti-tumor and anti-angiogenesis of plant flavonoids from the cellular level, molecular level and animal models level, which can provide a reference for further development and utilization of flavonoids in antitumor and anti-angiogenesis.

Research Progress Of Difference Between Electronic Tongue And Real Taste Evaluation, Wang Xingya, Pang Guangchang, Li Yang

Food and Machinery

Electronic tongue is a new analysis and detection equipment to study liquid sample information, in recent years, which has been more widely used in food industry. This paper introduces the basic principles of electronic tongue technology, similarities and differences with real evaluation methods of taste, status of equipment and its application in the food field, in order to propose new ideas for the development of electronic tongue equipment.

Quaker Campus, January 28, 2016 (Vol. 102, Issue 14), Whittier College

Quaker Campus

No abstract provided.

Mutations In Mtr4 Structural Domains Reveal Their Important Role In Regulating TrnaI Met Turnover In Saccharomyces Cerevisiae And Mtr4p Enzymatic Activities In Vitro, Yan Li, Joseph Burclaff, James T. Anderson

Biological Sciences Faculty Research and Publications

RNA processing and turnover play important roles in the maturation, metabolism and quality control of a large variety of RNAs thereby contributing to gene expression and cellular health. The TRAMP complex, composed of Air2p, Trf4p and Mtr4p, stimulates nuclear exosome-dependent RNA processing and degradation in Saccharomyces cerevisiae. The Mtr4 protein structure is composed of a helicase core and a novel so-called arch domain, which protrudes from the core. The helicase core contains highly conserved helicase domains RecA-1 and 2, and two structural domains of unclear functions, winged helix domain (WH) and ratchet domain. How the structural domains (arch, WH …

Is Protection Against Florivory Consistent With The Optimal Defense Hypothesis?, Adrienne L. Godschalx, Lauren Stady, Benjamin Watzig, Daniel J. Ballhorn

Biology Faculty Publications and Presentations

Background: Plant defense traits require resources and energy that plants may otherwise use for growth and reproduction. In order to most efficiently protect plant tissues from herbivory, one widely accepted assumption of the optimal defense hypothesis states that plants protect tissues most relevant to fitness. Reproductive organs directly determining plant fitness, including flowers and immature fruit, as well as young, productive leaf tissue thus should be particularly well-defended. To test this hypothesis, we quantified the cyanogenic potential (HCNp)—a direct, chemical defense—systemically expressed in vegetative and reproductive organs in lima bean (Phaseolus lunatus), and we tested susceptibility of these …

Wendland, Claire L. A Heart For The Work: Journeys Through An African Medical School. Chicago: University Of Chicago Press, 2010. 330pp., Iruka N. Okeke

Journal of Retracing Africa

No abstract provided.

Scorpions Of Ethiopia. Part Iv. Genus Uroplectes Peters, 1861(Scorpiones: Buthidae), František Kovařík, Graeme Lowe, David Hoferek, Jana Plíšková, František Šťáhlavský

Euscorpius

All data about the distribution of Uroplectes fischeri (Karsch, 1879) in Ethiopia and Somalia are summarized. U. fischeri is fully illustrated with color photos of habitus and locality. Uroplectoides abyssinicus Lourenço, 1998 is discussed and synonymized with U. fischeri. Genus Uroplectoides Lourenço, 1998 is synonymized with Uroplectes Peters, 1861. Hemispermatophore of U. fischeri was extracted and illustrated for the first time. In addition to morphological analysis we also describe the karyotype of male U. fischeri from Ethiopia (2n=28).

Toward A Future Adult Learning Community: If Socrates Had A Pc, Michael C. Pickett

Bollinger-Rosado Teaching & Learning Effectiveness Symposium Proceedings

The integration of educational technologies in adult learning environments is viewed from three distinct perspectives. The three perspectives are the structuralist, the means-end, and finally, a view of technology as an extension of oneself based in the situatedness of an experiential-type learning environment.

The various constructs of adult learning are reviewed and a framework for future adult learning communities is proposed that identifies the learner and educator provided components needed for an effective adult learning experience.

The Contribution Of Cancer Associated Fibroblasts In Breast Cancer Progression, Sanket H. Shah

Open Access Dissertations

Cancer Associated Fibroblasts (CAFs) are an integral component of the TME, and the majority of breast tumor stroma is comprised of CAFs. Multiple juxtacrine and paracrine interactions occur between cancer cells and CAFs that direct tumor progression. These interactions occur via soluble agents, including cytokines, hormones, growth factors, and secreted microRNAs. Some of these soluble agents induce MAPK activation in tumor cells. Our lab has established that MAPK activation in tumor cells is one of the key mechanisms involved in repression of ER. MAPK activation in tumor cells leads to alteration in miRNA expression. We previously identified a microRNA signature …

Utilization Of The Clinical Laboratory For The Implementation Of Concussion Biomarkers In Collegiate Football And The Necessity Of Personalized And Predictive Athlete Specific Reference Intervals, Stefanie Podlog (Nee Schulte), Natalie N. Rasmussen, Joseph W. Mcbeth, Patrick Q. Richards, Eric Yochem, David J. Petron, Frederick G. Strathmann

Athletic Training Collection

Background: A continued interest in concussion biomarkers makes the eventual implementation of identified biomarkers into routine concussion assessment an eventual reality. We sought to develop and test an interdisciplinary approach that could be used to integrate blood-based biomarkers into the established concussion management program for a collegiate football team.

Methods: We used a CLIA-certified laboratory for all testing and chose biomarkers where clinically validated testing was available as would be required for results used in clinical decision making. We summarized the existing methods and results for concussion assessment across an entire season to identify and demonstrate the challenges with the …

Volume 107 Issue 13, Southwestern Oklahoma State University

The Southwestern - Archive

No abstract provided.

The Bates Student - Volume 146 Number 11 - January 27, 2016, Bates College

The Bates Student

No abstract provided.

College Of Engineering Undergraduate Advisor Receives National Award | College Of Engineering, Usu College Of Engineering

College of Engineering News

Jan. 27, 2016 – An undergraduate advisor in the College of Engineering has been selected to receive a major award from the National Academic Advising Association, or NACADA.

Katherine Grover, who advises biological and mechanical engineering students in the College of Engineering, will receive the 2016 Region 10 Excellence in Advising – New Advisor Award at an upcoming conference in Santa Fe, N.M.

Fs Transcript 2016-01-27, Northern Illinois University

Faculty Senate Archives

No abstract provided.