Digital Commons Network^™

The Tidewater Z-Degree And The Intro Model For Sustaining Oer Adoption, David Wiley, Linda Williams, Daniel Demarte, John Hilton

Entrepreneurship Faculty Research

A growing body of research confirms the financial and academic benefits that accrue to students whose faculty adopt open educational resources, or OER. While there are no content licensing costs associated with using OER, there are several real costs that must be incurred by an institution that chooses to support its faculty in adopting OER. The Z-Degree initiative at Tidewater Community College utilizes only OER for the 21 courses, providing a pathway for students to earn an associate of science degree in business administration without ever buying a textbook. The authors introduce and illustrate the INTRO (Increased Tuition Revenue through …

From Clinging To Digging: The Postembryonic Skeletal Ontogeny Of The Indian Purple Frog, Nasikabatrachus Sahyadrensis (Anura: Nasikabatrachidae), Gayani Senevirathne, Ashish Thomas, Ryan R. Kerney, James Hanken, S. D. Biju, Madhava Meegaskumbura

Biology Faculty Publications

The Indian Purple frog, Nasikabatrachus sahyadrensis, occupies a basal phylogenetic position among neobatrachian anurans and has a very unusual life history. Tadpoles have a large ventral oral sucker, which they use to cling to rocks in torrents, whereas metamorphs possess adaptations for life underground. The developmental changes that underlie these shifts in habits and habitats, and especially the internal remodeling of the cranial and postcranial skeleton, are unknown. Using a nearly complete metamorphic series from free-living larva to metamorph, we describe the postembryonic skeletal ontogeny of this ancient and unique monotypic lineage. The torrent-dwelling larva possesses a dorsoventrally flattened …

Unearthing The Fossorial Tadpoles Of The Indian Dancing Frog Family Micrixalidae, Gayani Senevirathne, Sonali Garg, Ryan R. Kerney, Madhava Meegaskumbura, S. D. Biju

Biology Faculty Publications

Tadpoles of the monotypic Indian dancing frog family Micrixalidae have remained obscure for over 125 years. Here we report the discovery of the elusive tadpoles of Micrixalus herrei from the sand beds of a forested stream in southern Western Ghats, and confirm their identity through DNA barcoding. These actively burrowing tadpoles lead an entirely fossorial life from eggs to late metamorphic stages. We describe their internal and external morphological characters while highlighting the following features: eel-like appearance, extensively muscularized body and tail, reduced tail fins, skin-covered eyes, delayed development of eye pigmentation in early pre-metamorphic stages (Gosner stages 25–29), prominent …

Academics: The Newsletter Of The Swosu College Of Arts And Sciences, Peter Grant

aCAdemicS: The Newsletter of the SWOSU College of Arts & Sciences

No abstract provided.

Motor And Hippocampal Dependent Spatial Learning And Reference Memory Assessment In A Transgenic Rat Model Of Alzheimer's Disease With Stroke, Jennifer L. Au, Nina Weishaupt, Hayley J. Nell, Shawn N. Whitehead, David F. Cechetto

Anatomy and Cell Biology Publications

Alzheimer's disease (AD) is a debilitating neurodegenerative disease that results in neurodegeneration and memory loss. While age is a major risk factor for AD, stroke has also been implicated as a risk factor and an exacerbating factor. The co-morbidity of stroke and AD results in worsened stroke-related motor control and AD-related cognitive deficits when compared to each condition alone. To model the combined condition of stroke and AD, a novel transgenic rat model of AD, with a mutated form of amyloid precursor protein (a key protein involved in the development of AD) incorporated into its DNA, is given a small …

Automated Discrimination Of Dicentric And Monocentric Chromosomes By Machine Learning-Based Image Processing., Yanxin Li, Joan H Knoll, Ruth C Wilkins, Farrah N Flegal, Peter K Rogan

Biochemistry Publications

Dose from radiation exposure can be estimated from dicentric chromosome (DC) frequencies in metaphase cells of peripheral blood lymphocytes. We automated DC detection by extracting features in Giemsa-stained metaphase chromosome images and classifying objects by machine learning (ML). DC detection involves (i) intensity thresholded segmentation of metaphase objects, (ii) chromosome separation by watershed transformation and elimination of inseparable chromosome clusters, fragments and staining debris using a morphological decision tree filter, (iii) determination of chromosome width and centreline, (iv) derivation of centromere candidates, and (v) distinction of DCs from monocentric chromosomes (MC) by ML. Centromere candidates are inferred from 14 image …

Notochord Cells In Intervertebral Disc Development And Degeneration, Matthew R. Mccann, Cheryle A. Séguin

Bone and Joint Institute

© 2015 by the authors. All right reserved. The intervertebral disc is a complex structure responsible for flexibility, multi-axial motion, and load transmission throughout the spine. Importantly, degeneration of the intervertebral disc is thought to be an initiating factor for back pain. Due to a lack of understanding of the pathways that govern disc degeneration, there are currently no disease-modifying treatments to delay or prevent degenerative disc disease. This review presents an overview of our current understanding of the developmental processes that regulate intervertebral disc formation, with particular emphasis on the role of the notochord and notochord-derived cells in disc …

Structure And Function Of Gene Regulatory Networks Associated With Worker Sterility In Honeybees., Julia A Sobotka, Mark Daley, Sriram Chandrasekaran, Benjamin D Rubin, Graham J Thompson

Brain and Mind Institute Researchers' Publications

A characteristic of eusocial bees is a reproductive division of labor in which one or a few queens monopolize reproduction, while her worker daughters take on reproductively altruistic roles within the colony. The evolution of worker reproductive altruism involves indirect selection for the coordinated expression of genes that regulate personal reproduction, but evidence for this type of selection remains elusive. In this study, we tested whether genes coexpressed under queen-induced worker sterility show evidence of adaptive organization within a model brain transcriptional regulatory network (TRN). If so, this structured pattern would imply that indirect selection on nonreproductive workers has influenced …

When Is A Varicocele Repair Indicated: The Dilemma Of Hypogonadism And Erectile Dysfunction?, Ali A. Dabaja, Marc Goldstein

Urology Articles

In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain. The surgical treatment of varicocele for hypogonadism is controversial and debated. Recently, multiple reports in the literature have suggested that varicocele is associated with hypogonadism and varicocele repair can increase testosterone levels. Men with hypogonadal symptoms should have at least two serum testosterone levels. Microsurgical varicocelectomy may be beneficial for men with clinically palpable varicoceles with documented hypogonadism. In this review, we summarize the most recent literature linking varicocele to hypogonadism and sexual dysfunction and the impact of repair …

Discordance Between Morphological And Taxonomic Diversity: Land Snails Of Oceanic Archipelagos, Kostas Triantis, François Rigal, Christine Parent, Kenneth Hayes

Department of Biology Faculty Publications

AimMorphological and taxonomic diversity are intuitive measures of biological diversity. Previous studies have shown discordance between these measures at large spatial and temporal scales, but the implications of this pattern for the underlying processes are not understood. Using oceanic archipelagos as spatial units, we examine potential links between the morphological and taxonomic diversity of their land snail faunas in a biogeographical framework.LocationEleven major oceanic archipelagos.MethodsFor each archipelago, we assembled lists of indigenous land snail species, classified by family and genus, with shell height and width for each species (1723 species in total). We used biogeographic and climatic variables as potential …

Antiretroviral Drugs-Loaded Nanoparticles Fabricated By Dispersion Polymerization With Potential For Hiv/Aids Treatment, Winston Anderson

Department of Biology Faculty Publications

Highly active antiretroviral (ARV) therapy (HAART) for chronic suppression of HIV replication has revolutionized the treatment of HIV/AIDS. HAART is no panacea; treatments must be maintained for life. Although great progress has been made in ARV therapy, HIV continues to replicate in anatomical and intracellular sites where ARV drugs have restricted access. Nanotechnology has been considered a platform to circumvent some of the challenges in HIV/AIDS treatment. Dispersion polymerization was used to fabricate two types (PMM and ECA) of polymeric nanoparticles, and each was successfully loaded with four ARV drugs (zidovudine, lamivudine, nevirapine, and raltegravir), followed by physicochemical characterization: scanning …

Testing Create At Community Colleges: An Examination Of Faculty Perspectives And Diverse Student Gains, Kristy L. Kenyon, Morgan E. Onorato, Alan J. Gottesman, Jamila Hoque, Sally G. Hoskins

Publications and Research

CREATE (Consider, Read, Elucidate the hypotheses, Analyze and interpret the data, and Think of the next Experiment) is an innovative pedagogy for teaching science through the intensive analysis of scientific literature. Initiated at the City College of New York, a minority-serving institution, and regionally expanded in the New York/New Jersey/Pennsylvania area, this methodology has had multiple positive impacts on faculty and students in science, technology, engineering, and mathematics courses. To determine whether the CREATE strategy is effective at the community college (2-yr) level, we prepared 2-yr faculty to use CREATE methodologies and investigated CREATE implementation at community colleges in seven …

Phagephisher: A Pipeline For The Discovery Of Covert Viral Sequences In Complex Genomic Datasets, Thomas Hatzopoulos, Siobhan C. Watkins, Catherine Putonti

Bioinformatics Faculty Publications

Obtaining meaningful viral information from large sequencing datasets presents unique challenges distinct from prokaryotic and eukaryotic sequencing efforts. The difficulties surrounding this issue can be ascribed in part to the genomic plasticity of viruses themselves as well as the scarcity of existing information in genomic databases. The open-source software PhagePhisher (http://www.putonti-lab.com/phagephisher) has been designed as a simple pipeline to extract relevant information from complex and mixed datasets, and will improve the examination of bacteriophages, viruses, and virally related sequences, in a range of environments. Key aspects of the software include speed and ease of use; PhagePhisher can be used with …

Identification Of Bovine Sperm Acrosomal Proteins That Interact With A 32-Kda Acrosomal Matrix Protein, Subir K. Nagdas, Linda Smith, Ilza Medina-Ortiz, Luisa Hernandez-Encarnacion, Samir Raychoudhury

College of Health, Science, and Technology

Mammalian fertilization is accomplished by the interaction between sperm and egg. Previous studies from this laboratory have identified a stable acrosomal matrix assembly from the bovine sperm acrosome termed the outer acrosomal membrane–matrix complex (OMC). This stable matrix assembly exhibits precise binding activity for acrosin and N-acetylglucosaminidase. A highly purified OMC fraction comprises three major (54, 50, and 45 kDa) and several minor (38–19 kDa) polypeptides. The set of minor polypeptides (38–19 kDa) termed “OMCrpf polypeptides” is selectively solubilized by high-pH extraction (pH 10.5), while the three major polypeptides (55, 50, and 45 kDa) remain insoluble. Proteomic identification of the …

Critical Personnel And Continuity Of Operations Coop Planning Policy

Emergency Operations Policies

The University of Health Sciences and Pharmacy in St. Louis is committed to being institutionally resilient to all hazards that may impact its stakeholders and jeopardize its ability to fulfill its mission, and strives to develop innovative solutions to maintain the continuity of Critical Operating Units and preserve Mission Essential Functions for its students, faculty, staff, and visitors. This policy captures that commitment, and provides clarity, guidance, and resources to facilitate comprehensive Continuity of Operations (COOP) for office and department level entities at the University.

This policy applies to faculty and staff personnel working within an office or department designated …

Winona Currents Magazine, University Advancement - Winona State University

Winona Currents

This magazine published by Winona State University’s University Advancement was intended to inform WSU Alumni, students, faculty, staff and the greater community about Alumni and the university. The cover theme is: The Scientific Edge.

Circulating Mirna Biomarkers In Early Breast Cancer Detection Following Mammography, Alexa Lean, Jialu Lucy Yang, Xiaohui Tan, Christine B. Teal, Rachel F. Brem, Sidney W. Fu

GW Research Days 2016 - 2020

The currently accepted stepwise model of breast tumorigenesis assumes a gradual transition from normal breast epithelial cells to atypical ductal hyperplasia (ADH), to ductal carcinoma in situ (DCIS) and then to invasive ductal carcinoma (IDC). Percutaneous core needle biopsy (CNB) is the standard technique following an abnormal mammographic finding. However, CNB is less reliable in differentiating simple ADH (sADH) from ADH component coexisted with advanced lesions such as DCIS and/or IDC (cADH). Therefore, to identify and validate novel reliable molecular biomarkers is essential in order to improve the efficiency of therapeutic recommendations, as well as to minimize anxiety and unnecessary …

Medical Student Competency In Wound Care Guidelines, Sophia Akhiyat, Sean Mcnish, Kara S. Couch, Victoria K. Shanmugam

GW Research Days 2016 - 2020

Chronic wounds that have failed to heal after 3 months of appropriate wound care affect approximately 6.5 million people in the US with a prevalence of 1% and costs estimated at $25 billion per year. Medical students currently receive limited wound care training, yet to effectively manage chronic wounds, providers must both understand the biology of healing, and also remain up-to-date with wound care guidelines published by the Agency for Healthcare Research and Quality (AHRQ). The purpose of this student-led project was to investigate medical students' knowledge and comfort with wound care guidelines.

Effects Of Three-Times Daily Diet Soda Consumption For One Week On The Composition Of The Gut Microbiome In Healthy Young Adults, Jenna Abdelhadi, Domenica Simone, Charles Hadley King, Raja Mazumder, Keith A. Crandall, Allison C. Sylvetsky-Meni

GW Research Days 2016 - 2020

Epidemiologic studies report associations between artificial sweetener (ASW) consumption and metabolic abnormalities, yet well-designed human intervention studies in humans are limited. Given that ASW contain no or few calories, one potential mechanism through which ASW may influence metabolic risk is through altering the gut microbiota. As alterations in the gut microbiota are known to be implicated in the development of metabolic disease, the purpose of this study was to investigate the effects of one week of three times daily diet soda (with ASW) consumption on the gut microbiota in healthy college students. We hypothesized that participants randomized to consume diet …

Calvin Theological Seminary Forum: March 2016, Julius T. Medenblik, Cory Willson, Mary Vanden Berg, Sarah Schreiber

Calvin Theological Seminary Forum (2002- )

Articles
3 - From the President: How Now Shall We Live? by Jul Medenblik
4 - Every Believer Called to Mission by Cory Willson
6 - Prayers from the Missional Conference by Mary Vanden Berg and Sarah Schreiber
8 - Bavinck’s Reformed Dogmatics by John Bolt
9 - Meet Herman Bavinck by Jessica Driesenga
12 - Fostering Formation for Mission in Our Classrooms by Kristy Manion
15 - Is There a Future for Sacrifice? by Erin Zoutendam
16 - Taste and See Israel Trip by Paula Seales
18 - Church Growth and Its Challenges in Ethiopia by Fikre Norcha

Mother-Daughter Team On Sustainable Food Movement Rising, March 23, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Pbio Colloquium | Global Biodiversity Of Myxomycetes, March 18, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Tri Beta Hosts District Convention Kopchick Gives Keynote, March 19, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Kennedy Lecture | Series Marion Nestle, March 21, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Intramembrane Congestion Effects On Lysenin Channel Voltage-Induced Gating, Eric Krueger, Sheenah Bryant, Nisha Shrestha, Tyler Clark, Charles Hanna, David Pink, Daniel Fologea

Physics Faculty Publications and Presentations

All cell membranes are packed with proteins. The ability to investigate the regulatory mechanisms of protein channels in experimental conditions mimicking their congested native environment is crucial for understanding the environmental physicochemical cues that may fundamentally contribute to their functionality in natural membranes. Here we report on investigations of the voltage-induced gating of lysenin channels in congested conditions experimentally achieved by increasing the number of channels inserted into planar lipid membranes. Typical electrophysiology measurements reveal congestion-induced changes to the voltage-induced gating, manifested as a significant reduction of the response to external voltage stimuli. Furthermore, we demonstrate a similar diminished voltage …

Teacher Internship Project - James C. Enochs High School, Michele Marie Schilperoort

Agricultural Education: Graduate Internship Reports

This internship and project report includes validation documents required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The documents are concurrently used for the Agriculture Incentive Grant review process at James C. Enochs High School conducted by representatives of the California Department of Education. The internship includes the development of 30 raised garden beds for the Agriculture Department. The supporting material includes information to receive state and local funding, outline the goals and objectives of the program, along with an overview of Enochs agriculture program and community

Graduate Internship Report - Thomas Downey High School, Michael Christian Schilperoort

Agricultural Education: Graduate Internship Reports

This internship/project report includes validation documents required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The documents are concurrently used for the Agriculture Incentive Grant review process at Thomas Downey High School conducted by representatives of the California Department of Education. The internship included the development of a garden area space to be utilized for Supervised Agriculture Experience projects.

Proceedings Of The 43rd Annual Meeting, Southern Soybean Disease Workers (March 9-10, 2016, Pensacola Beach, Florida), Trey Price, Tom Allen, Travis Faske, Eduardo Chagas Da Silva

Southern Soybean Disease Workers: Conference Proceedings

Contents

Schedule

Southern United States Soybean Disease Loss Estimates for 2015. TW Allen, CA Bradley, JP Damicone, NS Dufault, TR Faske, CA Hollier, T Isakeit, RC Kemerait, NM Kleczewski, SR Koenning, HL Mehl, JD Mueller, C Overstreet, PP Price, EJ Sikora, TN Spurlock, and H Young

Soilborne Disease Symposium (Tom Allen, moderator)

Integrated management of sudden death syndrome. D Mueller, L Leandro, Y Kandel, C Bradley, M Chilvers, A Tenuta, and K Wise

Field screening for stem canker: an outdated exercise or a necessary service for soybean growers? K Rowe and T Kirkpatrick

Nematode associated diseases in soybean. C Overstreet, …

Striking A Balance: Ensuring The Safety And Efficacy Of A Drug's Use, While Recognizing The First Amendment Protection Of Truthful, Non-Misleading Off-Label Drug Communications, Hannah Smoot Combs

First Amendment Law Review

No abstract provided.

A Case Report Of Acute Cellular Rejection Following Intestinal Transplantation Managed With Adalimumab, B Rao, Syed-Mohammed Jafri, M Kazimi, Keith Mullins, Mohammad Raoufi, M C. Segovia

Gastroenterology Articles

There is a higher incidence of acute cellular rejection (ACR) in small bowel transplantation (SBT) compared with transplantation of other solid organs. Although there are reports on the use of infliximab to successfully treat ACR refractory to other treatments, there are no reports, to our knowledge, regarding the use of adalimumab. We present a case of a female patient with a history of Crohn's disease who underwent an isolated SBT and developed an episode of severe ACR. She was initially treated with methylprednisolone, thymoglobulin, basiliximab, and a dosage adjustment of tacrolimus. Results of repeat endoscopies and biopsies revealed no significant …