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Articles 35191 - 35220 of 38783
Full-Text Articles in Entire DC Network
Rhizomatic Approaches To Screen-Based Music Notation, Lindsay R. Vickery
Rhizomatic Approaches To Screen-Based Music Notation, Lindsay R. Vickery
Research outputs 2014 to 2021
The rhizome concept explored by Deleuze and Guatarri has had an important influence on formal thinking in music and new media. This paper explores the development of rhizomatic musical scores that are arranged cartographically with nodal points allowing for alternate pathways to be traversed. The challenges of pre-digital exemplars of rhizomatic structure are discussed. It follows the development of concepts and technology used in the creation of five works by the author Ubahn c. 1985: the Rosenberg Variations [2012], The Last Years [2012], Sacrificial Zones [2014], detritus [2015] and trash vortex [2015]. this paper discusses the potential for the evolution …
Peer Learning A Pedagogical Approach To Enhance Online Learning: A Qualitative Exploration, Anita Raymond, Elizabeth Jacob, Darren Jacob, Judith Lyons
Peer Learning A Pedagogical Approach To Enhance Online Learning: A Qualitative Exploration, Anita Raymond, Elizabeth Jacob, Darren Jacob, Judith Lyons
Research outputs 2014 to 2021
Background:
Flexible online programs are becoming increasingly popular method of education for students, allowing them to complete programs in their own time and cater for lifestyle differences. A mixture of delivery modes is one way which allows for enhanced learning. Peer learning is another method of learning which is shown to foster collaboration and prepare healthcare students for their future careers. This paper reports on a project to combine peer and online learning to teach pharmacology to nursing students.
Objectives:
To explore undergraduate nursing student opinions of working in peer groups for online learning sessions in a pharmacology course.
Design: …
Impact Of Mooring Activities On Carbon Stocks In Seagrass Meadows, Oscar Serrano, R. Ruhon, Paul S. Lavery, Gary A. Kendrick, S. Hickey, Pere Masque, Ariane Arias-Ortiz, Andy D.L. Steven, Carlos M. Duarte
Impact Of Mooring Activities On Carbon Stocks In Seagrass Meadows, Oscar Serrano, R. Ruhon, Paul S. Lavery, Gary A. Kendrick, S. Hickey, Pere Masque, Ariane Arias-Ortiz, Andy D.L. Steven, Carlos M. Duarte
Research outputs 2014 to 2021
Boating activities are one of the causes that threaten seagrass meadows and the ecosystem services they provide. Mechanical destruction of seagrass habitats may also trigger the erosion of sedimentary organic carbon (Corg) stocks, which may contribute to increasing atmospheric CO2. This study presents the first estimates of loss of Corg stocks in seagrass meadows due to mooring activities in Rottnest Island, Western Australia. Sediment cores were sampled from seagrass meadows and from bare but previously vegetated sediments underneath moorings. The Corg stores have been compromised by the mooring deployment from 1930s onwards, which involved …
Distinction In Corrosion Resistance Of Selective Laser Melted Ti-6al-4v Alloy On Different Planes, Nianwei Dai, Laichang Zhang, Junxi Zhang, Xin Zhang, Qingzhao Ni, Yang Chen
Distinction In Corrosion Resistance Of Selective Laser Melted Ti-6al-4v Alloy On Different Planes, Nianwei Dai, Laichang Zhang, Junxi Zhang, Xin Zhang, Qingzhao Ni, Yang Chen
Research outputs 2014 to 2021
Electrochemical measurements and microstructural analysis were performed to study the corrosion resistance of different planes of Ti-6Al-4V alloy manufactured by selective laser melting (SLM). The electrochemical results suggest that its XY-plane possesses a better corrosion resistance compared to XZ-plane in 1 M HCl solution, in spite of slight difference in 3.5 wt.% NaCl solution, suggesting that the different planes exhibit more pronounced distinction in corrosion resistance in harsher solution system. The inferior corrosion resistance of XZ-plane is attributed to the presence of more α′ martensite and less β-Ti phase in microstructure for XZ-plane than for XY-plane of the SLM-produced Ti-6Al-4V …
Nothing Happens Here: Songs About Perth, Jon Stratton, Adam Trainer
Nothing Happens Here: Songs About Perth, Jon Stratton, Adam Trainer
Research outputs 2014 to 2021
This essay examines Perth as portrayed through the lyrics of popular songs written by people who grew up in the city. These lyrics tend to reproduce the dominant myths about the city: that it is isolated, that it is self-satisfied, that little happens there. Perth became the focus of song lyrics during the late 1970s time of punk with titles such as 'Arsehole of the Universe' and 'Perth Is a Culture Shock'. Even the Eurogliders' 1984 hit, 'Heaven Must Be There', is based on a rejection of life in Perth. However, Perth was also home to Dave Warner, whose songs …
Inactivation Of Cytomegalovirus In Breast Milk Using Ultraviolet-C Irradiation: Opportunities For A New Treatment Option In Breast Milk Banking, Megan L. Lloyd, Nurul Hod, Jothsna Jayaraman, Elizabeth A. Marchant, Lukas Christen, Peter Chiang, Peter E. Hartmann, Geoffrey R. Shellam, Karen N. Simmer
Inactivation Of Cytomegalovirus In Breast Milk Using Ultraviolet-C Irradiation: Opportunities For A New Treatment Option In Breast Milk Banking, Megan L. Lloyd, Nurul Hod, Jothsna Jayaraman, Elizabeth A. Marchant, Lukas Christen, Peter Chiang, Peter E. Hartmann, Geoffrey R. Shellam, Karen N. Simmer
Research outputs 2014 to 2021
Pasteurized donor human milk is provided by milk banks to very preterm babies where their maternal supply is insufficient or unavailable. Donor milk is currently processed by Holder pasteurization, producing a microbiologically safe product but significantly reducing immunoprotective components. Ultraviolet-C (UV-C) irradiation at 254 nm is being investigated as an alternative treatment method and has been shown to preserve components such as lactoferrin, lysozyme and secretory IgA considerably better than Holder pasteurization. We describe the inactivation of cytomegalovirus, a virus commonly excreted into breast milk, using UV-C irradiation. Full replication was ablated by various treatment doses. However, evidence of viral …
Photonic Microstructures For Energy-Generating Clear Glass And Net-Zero Energy Buildings, Mikhail Vasiliev, Ramzy Alghamedi, Mohammad Alam, Kamal Alameh
Photonic Microstructures For Energy-Generating Clear Glass And Net-Zero Energy Buildings, Mikhail Vasiliev, Ramzy Alghamedi, Mohammad Alam, Kamal Alameh
Research outputs 2014 to 2021
Transparent energy-harvesting windows are emerging as practical building-integrated photovoltaics (BIPV), capable of generating electricity while simultaneously reducing heating and cooling demands. By incorporating spectrally-selective diffraction gratings as light deflecting structures of high visible transparency into lamination interlayers and using improved spectrally-selective thin-film coatings, most of the visible solar radiation can be transmitted through the glass windows with minimum attenuation. At the same time, the ultraviolet (UV) and a part of incident solar infrared (IR) radiation energy are converted and/or deflected geometrically towards the panel edge for collection by CuInSe2 solar cells. Experimental results show power conversion efficiencies in excess …
Suppression Of Neutrophil-Mediated Tissue Damage—A Novel Skill Of Mesenchymal Stem Cells, Dongsheng Jiang, Jana Muschhammer, Yu Qi, Andrea Kügler, Juliane C. De Vries, Mona Saffarzadeh, Anca Sindriaru, Seppe V. Beken, Meinhard Wlaschek, Mark A. Kluth, Christoph Ganss, Natasha Y. Frank, Markus H. Frank, Klaus T. Preissner, Karin Scharffetter-Kochanek
Suppression Of Neutrophil-Mediated Tissue Damage—A Novel Skill Of Mesenchymal Stem Cells, Dongsheng Jiang, Jana Muschhammer, Yu Qi, Andrea Kügler, Juliane C. De Vries, Mona Saffarzadeh, Anca Sindriaru, Seppe V. Beken, Meinhard Wlaschek, Mark A. Kluth, Christoph Ganss, Natasha Y. Frank, Markus H. Frank, Klaus T. Preissner, Karin Scharffetter-Kochanek
Research outputs 2014 to 2021
Mesenchymal stem cells (MSCs) are crucial for tissue homeostasis and regeneration. Though of prime interest, their potentially protective role on neutrophil-induced tissue damage, associated with high morbidity and mortality, has not been explored in sufficient detail. Here we report the therapeutic skill of MSCs to suppress unrestrained neutrophil activation and to attenuate severe tissue damage in a murine immune-complex mediated vasculitis model of unbalanced neutrophil activation. MSC-mediated neutrophil suppression was due to intercellular adhesion molecule 1-dependent engulfment of neutrophils by MSCs, decreasing overall neutrophil numbers. Similar to MSCs in their endogenous niche of murine and human vasculitis, therapeutically injected MSCs …
Permanent Slides For Morphological Studies Of Small Crustaceans: Serban's Method And Its Variation Applied On Bathynellacea (Malacostraca), Giulia Perina, Ana I. Camacho
Permanent Slides For Morphological Studies Of Small Crustaceans: Serban's Method And Its Variation Applied On Bathynellacea (Malacostraca), Giulia Perina, Ana I. Camacho
Research outputs 2014 to 2021
Morphological studies of small invertebrates often involve the preparation of slides to observe minute body parts under a compound microscope. Preparation should facilitate observation, through traditional optical microscopy, of small surface structures on different planes, like pores, spines and setae. Various methods and techniques, using different mounting media that specialists have adopted to observe and preserve small crustaceans, have their advantages and disadvantages.Within the order Bathynellacea, specimens in the family Bathynellidae are particularly challenging due to their small size (0.5 to 2.25 mm body length) and very delicate exoskeleton, which tends to be completely digested when using common clearing mounting …
The Influence Of The Sex Of And Prior Relationship Between The Perpetrator And Victim On Perceptions Of Stalking: A Qualitative Analysis, Jeff Bath, Adrian J. Scott
The Influence Of The Sex Of And Prior Relationship Between The Perpetrator And Victim On Perceptions Of Stalking: A Qualitative Analysis, Jeff Bath, Adrian J. Scott
Research outputs 2014 to 2021
The sex of and prior relationship between the perpetrator and victim have been shown to influence perceptions of stalking. To explore the ways in which shared assumptions around these factors interact to shape perceptions of stalking, this study analyses the deliberations of mock juries as they attempt to reach a unanimous verdict on a hypothetical stalking case summary. Twelve mock juries comprising between five and six ‘jurors’ (n = 64) were presented with one of three versions of a case summary (stranger, acquaintance, and ex-partner) describing a man stalking a woman or a woman stalking a man. Thematic analysis shows …
Interrogating Power And Disrupting The Discourse About Onslow And The Gas Hubs, Kayt Davies, Karma Barndon
Interrogating Power And Disrupting The Discourse About Onslow And The Gas Hubs, Kayt Davies, Karma Barndon
Research outputs 2014 to 2021
When government statements talk about a secret deal with a multinational consortium that will see more than A$250 million spent on a town with a population of around 1000 people, questions need to be asked. Basic maths equates the spend to around $250,000 a person and yet many people in the town are unhappy about the whole deal. 'Tracking Onslow' was a collaboration between a university and a local government that used journalism as a methodology to document and interrogate the interaction between Chevron, the state and local governments and the Onslow community over a three-year period. This article focuses …
Building Online Community On Snac: A Netnographic Study Of The Early Years Sector, Ruth Wallace, Leesa Costello, Amanda Devine
Building Online Community On Snac: A Netnographic Study Of The Early Years Sector, Ruth Wallace, Leesa Costello, Amanda Devine
Research outputs 2014 to 2021
‘‘Build it and they will come,’’ an adage critiqued as a common misconception of participatory engagement with online communities. Previous research indicated that a netnographic approach based upon researcher– participant engagement would provide the best opportunity to build and sustain a successful support community [...].
An Automated Approach For Digital Forensic Analysis Of Heterogeneous Big Data, Hussam Mohammed, Nathan Clarke, Fudong Li
An Automated Approach For Digital Forensic Analysis Of Heterogeneous Big Data, Hussam Mohammed, Nathan Clarke, Fudong Li
Research outputs 2014 to 2021
The major challenges with big data examination and analysis are volume, complex interdependence across content, and heterogeneity. The examination and analysis phases are considered essential to a digital forensics process. However, traditional techniques for the forensic investigation use one or more forensic tools to examine and analyse each resource. In addition, when multiple resources are included in one case, there is an inability to cross-correlate findings which often leads to inefficiencies in processing and identifying evidence. Furthermore, most current forensics tools cannot cope with large volumes of data. This paper develops a novel framework for digital forensic analysis of heterogeneous …
Data Journalism Classes In Australian Universities: Educators Describe Progress To Date, Kayt Davies, Trevor Cullen
Data Journalism Classes In Australian Universities: Educators Describe Progress To Date, Kayt Davies, Trevor Cullen
Research outputs 2014 to 2021
This article examines the extent to which data journalism (DJ) is being taught in Australian universities. It presents the results of interviews with 35 journalism academics about how they are incorporating data journalism into their courses. It includes details about the types of data journalism skills they are teaching, the resources they are using and the hindrances that have met or are making it difficult to teach data journalism. These hindrances include low and varied levels of quantitative literacy and math aversion among students, lack of time for upskilling and limited room in their courses for new material. The study …
Towards A Participatory Netnography: Collaborating With Children In Virtual Worlds Research, Ashley Donkin, Donell Holloway, Lelia Green
Towards A Participatory Netnography: Collaborating With Children In Virtual Worlds Research, Ashley Donkin, Donell Holloway, Lelia Green
Research outputs 2014 to 2021
The new sociology of childhood has encouraged social researchers to incorporate children in as much of the research process as possible. However, whilst some success has been achieved within traditional ethnographic studies, netnography has been slow to make this a reality. This article discusses the previous online research into children’s virtual worlds, which has rarely incorporated young children into the data collection or research analysis processes. The opportunity for researchers to use participatory approaches to collaborating with their child participants and collecting online data is limited due to ethical constraints. The ethical challenges of conducting netnography are compounded by a …
Headline Grabs For Music: The Development Of An Ipad Score Generator, Cat Hope, Stuart James, Aaron Wyatt
Headline Grabs For Music: The Development Of An Ipad Score Generator, Cat Hope, Stuart James, Aaron Wyatt
Research outputs 2014 to 2021
This paper-demonstration provides an overview of an generative music score adapted for the iPad by the Decibel new music ensemble. The original score `Loaded (NSFW)’ (2015) is by Western Australian composer Laura Jane Lowther, and is scored for ensemble and electronics, commissioned for a performance in April 2015 at the Perth Institute of Contemporary Arts. It engages and develops the Decibel Score Player application, a score reader and generator for the iPad as a tool for displaying an interactive score that requires performers to react to news headlines through musical means. The paper will introduce the concept for the player, …
Examining Student Ict Ownership, Use And Preferences Towards Electronically Delivered Learning Resources In Nakhon Phanom University And Sakon Nakhon Rajabhat University, Yuwanuch Gulatee, Vijittra Vonganusith, Jeremy E. Pagram, Martin G. Cooper
Examining Student Ict Ownership, Use And Preferences Towards Electronically Delivered Learning Resources In Nakhon Phanom University And Sakon Nakhon Rajabhat University, Yuwanuch Gulatee, Vijittra Vonganusith, Jeremy E. Pagram, Martin G. Cooper
Research outputs 2014 to 2021
The objectives of this research were 1) to find students’ ownership of technology devices, ownership, soft-ware facility, and preferences, 2) to find out what devices instructors use in the classroom, 3) to find out how the students use the online learning that the university provided for them, and 4) to examine students’ software skills. The questionnaire and the interview instruments were designed to clarify participants’ attitudes, and used a Likert scale. Surveys and qualitative research design were developed using Qualtrics software, which is an online research survey tool that can be used for a whole range of data gathering purposes …
A Case-Control Study In An Orcadian Population Investigating The Rrelationship Between Human Plasma N-Glycans And Metabolic Syndrome, Fiona Mclachlan, Maria Timofeeva, Mairead Bermingham, Sarah Wild, Igor Rudan, Gordon Lauc, Wei Wang, Harry Campbell, James Wilson, Evropi Theodoratou
A Case-Control Study In An Orcadian Population Investigating The Rrelationship Between Human Plasma N-Glycans And Metabolic Syndrome, Fiona Mclachlan, Maria Timofeeva, Mairead Bermingham, Sarah Wild, Igor Rudan, Gordon Lauc, Wei Wang, Harry Campbell, James Wilson, Evropi Theodoratou
Research outputs 2014 to 2021
Background:
Alterations in glycosylation patterns have long been known to reflect changes in cell metabolism. In this study, we investigated the relationship between human N-glycan profiles and metabolic syndrome.
Method:
Between 2005 and 2011, 2,155 individuals from the Orkney Islands (UK) were recruited and biological material, alongside phenotypic measures were collected. Individual N-glycan profiles were measured in plasma using weak anion exchange high performance liquid chromatography and calibrated hydrophilic interaction liquid chromatography. Pre-specified criteria were used to identify 564 cases with metabolic syndrome and 1475 controls. We applied logistic regression to test for association between this binary outcome against measured …
Floating Constructed Wetland For The Treatment Of Polluted River Water: A Pilot Scale Study On Seasonal Variation And Shock Load, Tanveer Saeed, Biprojit Paul, Rumana Afrin,, Abdullah Al-Muyeed, Guangzhi Sun
Floating Constructed Wetland For The Treatment Of Polluted River Water: A Pilot Scale Study On Seasonal Variation And Shock Load, Tanveer Saeed, Biprojit Paul, Rumana Afrin,, Abdullah Al-Muyeed, Guangzhi Sun
Research outputs 2014 to 2021
This paper reports the performance of a pilot scale floating constructed wetland (FCW), employed for the treatment of polluted water collected from Buriganga river in Bangladesh. The FCW system included a tank for accommodating collected water and a floating mat with media, to support the growth of two macrophyte species Phragmites australis and Canna indica. Mean mass removal rates of 0.66, 0.76, 0.08, 0.51, 2.49g/m2d were achieved for ammoniacal nitrogen (NH4-N), total inorganic nitrogen (TIN), phosphorus (P), biochemical oxygen demand (BOD), chemical oxygen demand (COD), respectively by the FCW. Nitrogen removal was via nitrification-denitrification processes, whereas filtration-sedimentation appeared to influence …
Suffering In Silence: The Survey Of Law Student Well-Being And The Reluctance Of Law Students To Seek Help For Substance Use And Mental Health Concerns, David Jaffe, Jerome Organ, Katherine Bender
Suffering In Silence: The Survey Of Law Student Well-Being And The Reluctance Of Law Students To Seek Help For Substance Use And Mental Health Concerns, David Jaffe, Jerome Organ, Katherine Bender
Scholarly Articles in Law Reviews & Journals
This article reports the results of the Survey of Law Student Well-Being (SLSWB) implemented in spring 2014 at fifteen law schools around the country. The SLSWB is the fi rst multischool study in over twenty years to address law student use of alcohol and street drugs, and the fi rst-ever multischool study to explore prescription drug use and the mental health concerns and helpseeking attitudes of law students. The results of the study indicate that roughly one-quarter to one-third of respondents reported frequent binge drinking or misuse of drugs, and/or reported mental health challenges. Moreover, the results indicated that signifi …
Applying The Health Justice Framework To Diabetes As A Community-Managed Social Phenomenon, Lindsay Wiley
Applying The Health Justice Framework To Diabetes As A Community-Managed Social Phenomenon, Lindsay Wiley
Scholarly Articles in Law Reviews & Journals
INTRODUCTION: In East Harlem, it is possible to take any simple nexus of people -the line at an A.T.M., a portion of a postal route, the members of a church choir -and trace an invisible web of diabetes that stretches through the group and out into the neighborhood, touching nearly every life with its menace.Ten years ago, the New York Times published "Bad Blood," a series of articles examining the impact of diabetes on the residents of New York City. In the years that followed, New York pioneered a series of groundbreaking legal interventions, including implementing measures to track diabetes …
Rendered Invisible: African American Low-Wage Workers And The Workplace Exploitation Paradigm, Llezlie Coleman
Rendered Invisible: African American Low-Wage Workers And The Workplace Exploitation Paradigm, Llezlie Coleman
Scholarly Articles in Law Reviews & Journals
The narrative of low-wage worker exploitation has increasingly narrowed in focus to reflect the experiences of undocumented immigrant workers whose immigration status makes them particularly vulnerable to wage theft and other denials of their substantive workplace rights. Indeed, much of the scholarship in this area rests solidly at the intersection of immigrant justice and employment law. This article disrupts this paradigm by arguing that this limited narrative has rendered African American low-wage workers invisible. It also draws from the voices of low-wage worker advocates who have borrowed from current activism to announce that #BlackWorkersMatter. Given the role of paradigms in …
National Legal Traditions At Work In The Jurisprudence Of The Court Of Justice Of The European Union: Symposium: Foreign Law In Constitutional Courts, Fernanda Nicola
National Legal Traditions At Work In The Jurisprudence Of The Court Of Justice Of The European Union: Symposium: Foreign Law In Constitutional Courts, Fernanda Nicola
Scholarly Articles in Law Reviews & Journals
Numerous scholars have commented on the judicial style of the Court of Justice of the European Union and its non-Herculean judges, generally disapproving of its minimalist reasoning, lack of transparency, and failure to draw openly on comparative legal sources to avoid inconsistencies and weaknesses in its legal reasoning. In a debate where both historians and sociologists have provided new avenues of research, the paucity of comparative lawyers is surprising because European law is a quintessential example of a transnational legal order. Since its inception, European judges, advocates general, and lawyers in Luxembourg have drawn inspiration from the different national legal …
The External Dimension Of Eu Investment Law, Fernanda Nicola
The External Dimension Of Eu Investment Law, Fernanda Nicola
Scholarly Articles in Law Reviews & Journals
EU trade and investment policy is in flux. The rate at which the global trade and investment architecture is evolving through the mega-regional Free Trade Agreements ("FTAs") is unprecedented. In this context, we explain how European lawyers and trade negotiators are addressing the newly acquired investment competence, while at the same time reforming investment arbitration and proposing new systems of dispute resolution at the international level. EU trade negotiators have put forward transformative proposals for investment chapters in their FTAs to safeguard, above all, the autonomy of the EU legal order in its relationship with international arbitration law. By mapping …
The Death Penalty And Mental Illness In International Human Rights Law, Richard Wilson
The Death Penalty And Mental Illness In International Human Rights Law, Richard Wilson
Scholarly Articles in Law Reviews & Journals
Introduction: This symposium primarily focuses on the extraordinary legal and personal saga of one man, Joe Giarratano, his decades-long heroic struggle to overturn his death sentence and, ultimately, to obtain his release and exoneration. Prior to the conference, my only acquaintance with the Giarratano case was the decision in Murray v. Giarratanol-the U.S. Supreme Court decision holding that the Sixth Amendment right to appointed counsel does not extend to the post-conviction stages of death penalty litigation. The symposium provided a much broader perspective on the saga of Joe Giarratano, whose own legal skills parallel those of the many lawyers involved …
The Court And The Cannonball: An Inside Look, Stephen Wermiel, Lee Levine
The Court And The Cannonball: An Inside Look, Stephen Wermiel, Lee Levine
Scholarly Articles in Law Reviews & Journals
As lawsuits over the right of publicity proliferate among athletes and other celebrities, there is renewed interest, by litigants and judges alike, in the one decision by the U.S. Supreme Court that addresses a tort action arising from a "publicity" related claim, Zacchini v. Scripps-Howard Broadcasting Co. Although the 1977 ruling is often cited as holding that the right of publicity tort survives constitutional scrutiny under the First Amendment, an examination of the case and of the Supreme Court justices' available papers shows that the Court did not view the case as presenting the type of claim that has become …
The Prosecutor's Ethical Duty To End Mass Incarceration, Angela J. Davis
The Prosecutor's Ethical Duty To End Mass Incarceration, Angela J. Davis
Scholarly Articles in Law Reviews & Journals
No abstract provided.
Development Of A Novel In Vivo Corneal Fibrosis Model In The Dog, K. M. Gronkiewicz, Elizabeth A. Giuliano, K. Kuroki, F. Bunyak, Ajay Sharma, L. B. C. Teixeira, C. W. Hamm, R. R. Mohan
Development Of A Novel In Vivo Corneal Fibrosis Model In The Dog, K. M. Gronkiewicz, Elizabeth A. Giuliano, K. Kuroki, F. Bunyak, Ajay Sharma, L. B. C. Teixeira, C. W. Hamm, R. R. Mohan
Pharmacy Faculty Articles and Research
The aim of this study was to develop a novel in vivo corneal model of fibrosis in dogs utilizing alkali burn and determine the ability of suberanilohydroxamic acid (SAHA) to inhibit corneal fibrosis using this large animal model. To accomplish this, we used seven research Beagle dogs. An axial corneal alkali burn in dogs was created using 1 N NaOH topically. Six dogs were randomly and equally assigned into 2 groups: A) vehicle (DMSO, 2 μL/mL); B) anti-fibrotic treatment (50 μM SAHA). The degree of corneal opacity, ocular health, and anti-fibrotic effects of SAHA were determined utilizing the Fantes grading …
Assessment Of Celecoxib Poly(Lactic-Co-Glycolic) Acid Nanoformulation On Drug Pharmacodynamics And Pharmacokinetics In Rats, Sam Harirforoosh, Kelsi O. West, Derek E. Murrell, James W. Denham, Peter C. Panus, Greg A. Hanley
Assessment Of Celecoxib Poly(Lactic-Co-Glycolic) Acid Nanoformulation On Drug Pharmacodynamics And Pharmacokinetics In Rats, Sam Harirforoosh, Kelsi O. West, Derek E. Murrell, James W. Denham, Peter C. Panus, Greg A. Hanley
Pharmacy Faculty Articles and Research
OBJECTIVE: Celecoxib (CEL) is a nonsteroidal anti-inflammatory drug (NSAID) showing selective cycloxygenase-2 inhibition. While effective as a pain reducer, CEL exerts some negative influence on renal and gastrointestinal parameters. This study examined CEL pharmacodynamics and pharmacokinetics following drug reformulation as a poly(lactic-co-glycolic) acid nanoparticle (NP).
MATERIALS AND METHODS: Rats were administered either vehicle (VEH) (methylcellulose solution), blank NP, 40 mg/kg CEL in methylcellulose, or an equivalent NP dose (CEL-NP). Plasma and urine (over 12 hrs) samples were collected prior to and post-treatment. The mean percent change from baseline of urine flow rate along with electrolyte concentrations in plasma …
Compelled Commercial Speech And The Consumer "Right To Know", Jonathan H. Adler
Compelled Commercial Speech And The Consumer "Right To Know", Jonathan H. Adler
Faculty Publications
Compelled commercial speech, including mandatory labeling and the disclosure of factually true information, should not be seen as a separate category of speech under the First Amendment. Rather, compelled commercial speech should be understood as a type of commercial speech and be subject to the same level of protection as commercial speech generally. Accordingly, commercial speech compulsions, such as mandatory disclosures and labeling requirements, must be supported by a substantial government interest under the Central Hudson framework. The assertion of a consumer “right to know” does not constitute such an interest and cannot, by itself, justify compelled commercial speech within …