Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2016

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 57301 - 57330 of 57374

Full-Text Articles in Entire DC Network

Solutions Visant L’Amélioration Des Conditions De Santé Et De Sécurité Des Poseurs De Revêtements De Sol, Monique Lortie, Sylvie Nadeau, Steve Vezeau Jan 2016

Solutions Visant L’Amélioration Des Conditions De Santé Et De Sécurité Des Poseurs De Revêtements De Sol, Monique Lortie, Sylvie Nadeau, Steve Vezeau

Rapports de recherche scientifique

La pose de revêtement de sol se divise en différentes spécialités : céramique, bois et revêtement souple. C’est ce dernier secteur qui nous intéresse, soit la pose de tapis (accrochés ou collés; en rouleau, en tuiles) ou de matériaux résilients (linoléum, vinyle, caoutchouc, gazon synthétique, etc.). Le métier de poseur de revêtement de sol est exigeant sur le plan physique (manutention de rouleaux très lourds, travail à genou prolongé, épandage de colle sur de grandes surfaces), mais aussi en matière de savoir-faire à développer. La pose exige de la précision, entre autres, pour ajuster les motifs et effectuer les raccords. …


The Protective Role Of Mlcp-Mediated Erm Dephosphorylation In Endotoxin-Induced Lung Injury In Vitro And In Vivo, Anita Kovacs-Kasa, Boris A. Gorshkov, Kyung-Mi Kim, Sanjiv Kumar, Stephen M. Black, David J. Fulton, Christiana Dimitropoulou, John D. Catravas, Alexander D. Verin Jan 2016

The Protective Role Of Mlcp-Mediated Erm Dephosphorylation In Endotoxin-Induced Lung Injury In Vitro And In Vivo, Anita Kovacs-Kasa, Boris A. Gorshkov, Kyung-Mi Kim, Sanjiv Kumar, Stephen M. Black, David J. Fulton, Christiana Dimitropoulou, John D. Catravas, Alexander D. Verin

Bioelectrics Publications

The goal of this study was to investigate the role of MLC phosphatase (MLCP) in a LPS model of acute lung injury (ALI). We demonstrate that ectopic expression of a constitutively-active (C/A) MLCP regulatory subunit (MYPT1) attenuates the ability of LPS to increase endothelial (EC) permeability. Down-regulation of MYPT1 exacerbates LPS-induced expression of ICAM1 suggesting an anti-inflammatory role of MLCP. To determine whether MLCP contributes to LPS-induced ALI in vivo, we utilized a nanoparticle DNA delivery method to specifically target lung EC. Expression of a C/A MYPT1 reduced LPS-induced lung inflammation and vascular permeability. Further, increased expression of the …


A Novel Copper (Ii) Complex Identified As A Potent Drug Against Colorectal And Breast Cancer Cells And As A Poison Inhibitor For Human Topoisomerase Iiᶐ, Shayna Sandhaus, Rosella Taylor, Tiffany Edwards, Alexis Huddleston, Stephen J. Beebe, Alvin A. Holder Jan 2016

A Novel Copper (Ii) Complex Identified As A Potent Drug Against Colorectal And Breast Cancer Cells And As A Poison Inhibitor For Human Topoisomerase Iiᶐ, Shayna Sandhaus, Rosella Taylor, Tiffany Edwards, Alexis Huddleston, Stephen J. Beebe, Alvin A. Holder

Bioelectrics Publications

A novel complex, [Cu(acetylethTSC)Cl]Cl · 0.25C2H5OH 1 (where acetylethTSC = (E)-N-ethyl-2-[1-(thiazol-2-yl)ethylidene]hydrazinecarbothioamide), was shown to have anti-proliferative activity against various colon and aggressive breast cancer cell lines. In vitro studies showed that complex 1 acted as a poison inhibitor of human topoisomerase IIᶐ which may account for the observed anti-cancer effects.


Disaster Preparedness And Response: A Survey Of U.S. Dental Hygienists, Brenda T. Bradshaw, Ann P. Bruhn, Tara L. Newcomb, Bridget T. Giles, Kathryn Simms Jan 2016

Disaster Preparedness And Response: A Survey Of U.S. Dental Hygienists, Brenda T. Bradshaw, Ann P. Bruhn, Tara L. Newcomb, Bridget T. Giles, Kathryn Simms

Dental Hygiene Faculty Publications

Purpose: The purpose of this study was to assess dental hygienists’ interests, current involvement, formal education, views, comfort levels, and intentions for involvement with disaster preparedness and response.

Methods: Dental hygienists (n=400) were asked to respond to a 21-item online survey. Data was analyzed using descriptive statistics, chi-square goodness-of-fit tests, and a paired-samples t-test. Common themes were identified and categorized from open-ended questions.

Results: A response rate of 84% (n=334) was obtained. Most respondents (97%) reported no involvement with disaster preparedness and response; however, a majority (86%) reported interest. Of those who indicated an interest in disaster preparedness and response, …


Latina Titans: A Journey Of Inspiration, Velma D. Menchaca, Shirley J. Mills, Filomena Leo Jan 2016

Latina Titans: A Journey Of Inspiration, Velma D. Menchaca, Shirley J. Mills, Filomena Leo

Organization and School Leadership Faculty Publications

This qualitative research examined the journey of renowned female leadership in higher education. Two top level Latina administrators of universities were interviewed extensively to discover their journey to leadership. The theoretical framework used was Latina critical race theory, feminist theory, and counter-storytelling. Themes that surfaced were strong supportive mother, fervent faith, humble beginnings, mentors, intelligence, and challenges not obstacles. These guiding themes serve as a path for Latinas who aspire to higher educational leadership positions.


Anatomy, Implant Selection And Placement Influence Spine Mechanics Associated With Total Disc Replacement, Justin F.M. Hollenbeck Jan 2016

Anatomy, Implant Selection And Placement Influence Spine Mechanics Associated With Total Disc Replacement, Justin F.M. Hollenbeck

Electronic Theses and Dissertations

Through aging and injury, the intervertebral disc of the lumbar spine can undergo degeneration, leading to collapse of the vertebrae and low back pain, a symptom that affects half the adult population in any given year. In an effort to reduce low back pain, total disc replacement treatment removes the degenerated disc, restores natural height and lordosis of the segment, and preserves motion at the joint. Patient anatomy, implant selection, and implant placement play significant roles in a patient's outcomes after total disc replacement surgery. Thus, the objective of the work presented in this thesis was to develop a suite …


Current Medical Research Winter/Spring 2015, Richard J. Fehring Jan 2016

Current Medical Research Winter/Spring 2015, Richard J. Fehring

College of Nursing Faculty Research and Publications

No abstract provided.


Success Stories And Emerging Themes In Conservation Physiology, Christine L. Madliger, Steven J. Cooke, Erica J. Crespi, Jennifer L. Funk, Kevin R. Hultine, Kathleen E. Hunt, Jason R. Rohr, Brent J. Sinclair, Cory D. Suski, Craig K. R. Willis, Oliver P. Love Jan 2016

Success Stories And Emerging Themes In Conservation Physiology, Christine L. Madliger, Steven J. Cooke, Erica J. Crespi, Jennifer L. Funk, Kevin R. Hultine, Kathleen E. Hunt, Jason R. Rohr, Brent J. Sinclair, Cory D. Suski, Craig K. R. Willis, Oliver P. Love

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The potential benefits of physiology for conservation are well established and include greater specificity of management techniques, determination of cause–effect relationships, increased sensitivity of health and disturbance monitoring and greater capacity for predicting future change. While descriptions of the specific avenues in which conservation and physiology can be integrated are readily available and important to the continuing expansion of the discipline of ‘conservation physiology’, to date there has been no assessment of how the field has specifically contributed to conservation success. However, the goal of conservation physiology is to foster conservation solutions and it is therefore important to assess whether …


General Practitioners’ Knowledge, Attitudes And Views Of Providing Preconception Care: A Qualitative Investigation, Obiamaka Ojukwu, Dilisha Patel, Judith Stephenson, Beth Howden, Jill Shawe Jan 2016

General Practitioners’ Knowledge, Attitudes And Views Of Providing Preconception Care: A Qualitative Investigation, Obiamaka Ojukwu, Dilisha Patel, Judith Stephenson, Beth Howden, Jill Shawe

School of Nursing and Midwifery

No abstract provided.


Deshazer, M.K.Mammographies: The Cultural Discourses Of Breast Cancer Narratives. Michigan: University Of Michigan Press. 2013. 239 Pp £28.50 Isbn 978–0472118823 (Hbk), J Tredinnick‐Rowe Jan 2016

Deshazer, M.K.Mammographies: The Cultural Discourses Of Breast Cancer Narratives. Michigan: University Of Michigan Press. 2013. 239 Pp £28.50 Isbn 978–0472118823 (Hbk), J Tredinnick‐Rowe

Peninsula Medical School

No abstract provided.


Getting The Right Balance: Insole Design Alters Static Balance In People With Diabetic Neuropathy, J Paton, S Glasser, R Collings, J Marsden Jan 2016

Getting The Right Balance: Insole Design Alters Static Balance In People With Diabetic Neuropathy, J Paton, S Glasser, R Collings, J Marsden

School of Health Professions

No abstract provided.


Levels Of Physical Dependence On Tobacco Among Adolescent Smokers In Cyprus, Costas A. Christophi, Despina Pampaka, Martha Paisi, Solonas Ioannou, Joseph R. Difranza Jan 2016

Levels Of Physical Dependence On Tobacco Among Adolescent Smokers In Cyprus, Costas A. Christophi, Despina Pampaka, Martha Paisi, Solonas Ioannou, Joseph R. Difranza

School of Nursing and Midwifery

No abstract provided.


Emergency Cricothyrotomy: Revised Anatomy And Its Implications For Clinical Practice, T Nutbeam, Dg Enki, R Clarke, T Luff, D Gay Jan 2016

Emergency Cricothyrotomy: Revised Anatomy And Its Implications For Clinical Practice, T Nutbeam, Dg Enki, R Clarke, T Luff, D Gay

School of Health Professions

No abstract provided.


Sometimes They Come Back: Examining The Threat Of Associated And Non-Associated And/Or Mentally Ill School Violence Perpetrators, Gordon A. Crews Jan 2016

Sometimes They Come Back: Examining The Threat Of Associated And Non-Associated And/Or Mentally Ill School Violence Perpetrators, Gordon A. Crews

Criminal Justice Faculty Publications

In this chapter it is argued that school violence and its potential in K-12 schools cannot be dealt with by simply removing the troublesome/problematic students from classrooms and/or school grounds. The expelling, suspending, incarcerating, or placing of a juvenile in an alternative school setting may only increase their anger against their former school and teachers. An anger which may continue to grow throughout their lives. Moreover, there is a growing trend of students who have failed to achieve in life returning to their former school and committing acts of violence. The author focuses on two types of these perpetrators. First, …


The Significant Other: A Longitudinal Analysis Of Significant Samples In Journalism Research, 2000–2014, Ben S. Wasike Jan 2016

The Significant Other: A Longitudinal Analysis Of Significant Samples In Journalism Research, 2000–2014, Ben S. Wasike

Communication Faculty Publications

This study examined the methodology journalism scholars use when studying significant samples, or “those persons who have attained an unusually pervasive and lasting reputation, regardless of whether that reputation be great or small.” Using Simonton’s work as the theoretical guide, the study content analyzed a census of articles published in 10 major journalism journals from 2000 to 2014. Results showed that the typical study examining significant samples is psychometric and is also quantitative, nomothetic, longitudinal, singularly focused, and exploratory. In addition, it uses macro units and observes the subject indirectly. The study also found similarities between the study of significant …


Sphingosine 1-Phosphate Lyase Ablation Disrupts Presynaptic Architecture And Function Via An Ubiquitin- Proteasome Mediated Mechanism, Dn Mitroi, Au Deutschmann, M Raucamp, I Karunakaran, K Glebov, M Hans, J Walter, J Saba, M Gräler, D Ehninger, E Sopova, O Shupliakov, D Swandulla, Echten-Deckert G Van Jan 2016

Sphingosine 1-Phosphate Lyase Ablation Disrupts Presynaptic Architecture And Function Via An Ubiquitin- Proteasome Mediated Mechanism, Dn Mitroi, Au Deutschmann, M Raucamp, I Karunakaran, K Glebov, M Hans, J Walter, J Saba, M Gräler, D Ehninger, E Sopova, O Shupliakov, D Swandulla, Echten-Deckert G Van

Peninsula Medical School

No abstract provided.


Proteome And Phosphoproteome Analysis Of Stratified Meningiomas, S Ferluga, J Dunn, E Lasonder, V Sharma, Da Hilton, C Adams, Co Hanemann Jan 2016

Proteome And Phosphoproteome Analysis Of Stratified Meningiomas, S Ferluga, J Dunn, E Lasonder, V Sharma, Da Hilton, C Adams, Co Hanemann

Peninsula Medical School

No abstract provided.


Posttraumatic Stress Disorder Among Older Patients With Chronic Obstructive Pulmonary Disease, Mc Chung, Rcm Jones, Sa Harding, J Campbell Jan 2016

Posttraumatic Stress Disorder Among Older Patients With Chronic Obstructive Pulmonary Disease, Mc Chung, Rcm Jones, Sa Harding, J Campbell

Peninsula Medical School

No abstract provided.


A Core Curriculum For Sociology In Uk Undergraduate Medical Education, T Collett, L Brooks, S Forrest, J Harden, M Kelly, K Kendall, Stewart S Macbride, M Sbaiti, F Stevenson Jan 2016

A Core Curriculum For Sociology In Uk Undergraduate Medical Education, T Collett, L Brooks, S Forrest, J Harden, M Kelly, K Kendall, Stewart S Macbride, M Sbaiti, F Stevenson

Peninsula Medical School

No abstract provided.


Can’T Count Or Won’T Count? Embedding Quantitative Methods In Substantive Sociology Curricula: A Quasi-Experiment, Malcolm Williams, Luke Sloan, Sin Yi Cheung, Carole Sutton, Sebastian Stevens, Libby Runham Jan 2016

Can’T Count Or Won’T Count? Embedding Quantitative Methods In Substantive Sociology Curricula: A Quasi-Experiment, Malcolm Williams, Luke Sloan, Sin Yi Cheung, Carole Sutton, Sebastian Stevens, Libby Runham

Peninsula Medical School

This paper reports on a quasi-experiment in which quantitative methods (QM) are embedded within a substantive sociology module. Through measuring student attitudes before and after the intervention alongside control group comparisons, we illustrate the impact that embedding has on the student experience. Our findings are complex and even contradictory. Whilst the experimental group were less likely to be distrustful of statistics and appreciate how QM inform social research, they were also less confident about their statistical abilities, suggesting that through ‘doing’ quantitative sociology the experimental group are exposed to the intricacies of method and their optimism about their own abilities …


A Qualitative Study Of Diverse Providers' Behaviour In Response To Commissioners, Patients And Innovators In England: Research Protocol, Rod Sheaff, Joyce Halliday, Mark Exworthy, Pauline Allen, Russell Mannion, Sheena Asthana, Alex Gibson, Jonathan Clark Jan 2016

A Qualitative Study Of Diverse Providers' Behaviour In Response To Commissioners, Patients And Innovators In England: Research Protocol, Rod Sheaff, Joyce Halliday, Mark Exworthy, Pauline Allen, Russell Mannion, Sheena Asthana, Alex Gibson, Jonathan Clark

Peninsula Medical School

Introduction: The variety of organisations providing National Health Service (NHS)-funded services in England is growing. Besides NHS hospitals and general practitioners (GPs), they include corporations, social enterprises, voluntary organisations and others. The degree to which these organisational types vary, however, in the ways they manage and provide services and in the outcomes for service quality, patient experience and innovation, remains unclear. This research will help those who commission NHS services select among the different types of organisation for different tasks. Research questions: The main research questions are how organisationally diverse NHS-funded service providers vary in their responsiveness to patient choice, …


Chromosomal Microarray Testing In Adults With Intellectual Disability Presenting With Comorbid Psychiatric Disorders, Kate Wolfe, André Strydom, Deborah Morrogh, Jennifer Carter, Peter Cutajar, Mo Eyeoyibo, Angela Hassiotis, Jane Mccarthy, Raja Mukherjee, Dimitrios Paschos, Nagarajan Perumal, Stephen Read, Rohit Shankar, Saif Sharif, Suchithra Thirulokachandran, Johan H. Thygesen, Christine Patch, Caroline Ogilvie, Frances Flinter, Andrew Mcquillin, Nick Bass Jan 2016

Chromosomal Microarray Testing In Adults With Intellectual Disability Presenting With Comorbid Psychiatric Disorders, Kate Wolfe, André Strydom, Deborah Morrogh, Jennifer Carter, Peter Cutajar, Mo Eyeoyibo, Angela Hassiotis, Jane Mccarthy, Raja Mukherjee, Dimitrios Paschos, Nagarajan Perumal, Stephen Read, Rohit Shankar, Saif Sharif, Suchithra Thirulokachandran, Johan H. Thygesen, Christine Patch, Caroline Ogilvie, Frances Flinter, Andrew Mcquillin, Nick Bass

Peninsula Medical School

Chromosomal copy-number variations (CNVs) are a class of genetic variants highly implicated in the aetiology of neurodevelopmental disorders, including intellectual disabilities (ID), schizophrenia and autism spectrum disorders (ASD). Yet the majority of adults with idiopathic ID presenting to psychiatric services have not been tested for CNVs. We undertook genome-wide chromosomal microarray analysis (CMA) of 202 adults with idiopathic ID recruited from community and in-patient ID psychiatry services across England. CNV pathogenicity was assessed using standard clinical diagnostic methods and participants underwent comprehensive medical and psychiatric phenotyping. We found an 11% yield of likely pathogenic CNVs (22/202). CNVs at recurrent loci, …


Patient- And Carer-Held Health Records: Can They Improve Annual Health Checks For Patients With Learning Disability?, Rohit Shankar, Guy Bradley-Smith, Philip Brigham, John Devapriam, Amy Osborne, Sharon Axby Jan 2016

Patient- And Carer-Held Health Records: Can They Improve Annual Health Checks For Patients With Learning Disability?, Rohit Shankar, Guy Bradley-Smith, Philip Brigham, John Devapriam, Amy Osborne, Sharon Axby

Peninsula Medical School

No abstract provided.


An Exploratory Analysis Of The Smoking And Physical Activity Outcomes From A Pilot Randomized Controlled Trial Of An Exercise Assisted Reduction To Stop Smoking Intervention In Disadvantaged Groups, Tom Paul Thompson, Colin J. Greaves, Richard Ayres, Paul Aveyard, Fiona C. Warren, Richard Byng, Rs Taylor, John L. Campbell, Michael Ussher, Colin Green, Susan Michie, Robert West, A Taylor Jan 2016

An Exploratory Analysis Of The Smoking And Physical Activity Outcomes From A Pilot Randomized Controlled Trial Of An Exercise Assisted Reduction To Stop Smoking Intervention In Disadvantaged Groups, Tom Paul Thompson, Colin J. Greaves, Richard Ayres, Paul Aveyard, Fiona C. Warren, Richard Byng, Rs Taylor, John L. Campbell, Michael Ussher, Colin Green, Susan Michie, Robert West, A Taylor

Peninsula Medical School

No abstract provided.


The Social, Relational And Mental Health Characteristics Of Justice-Involved Men In The South-West England, Alexandros Georgiadis, Richard Byng, Ross Coomber, Cath Quinn Jan 2016

The Social, Relational And Mental Health Characteristics Of Justice-Involved Men In The South-West England, Alexandros Georgiadis, Richard Byng, Ross Coomber, Cath Quinn

Peninsula Medical School

No abstract provided.


Global Patient Outcomes After Elective Surgery: Prospective Cohort Study In 27 Low-, Middle- And High-Income Countries, Danial Martin Jan 2016

Global Patient Outcomes After Elective Surgery: Prospective Cohort Study In 27 Low-, Middle- And High-Income Countries, Danial Martin

Peninsula Medical School

No abstract provided.


China To The Rescue? Implications Of Chinese Aid And Trade In Latin America Based On Evidence From Sino-African Cases, Jamie Curran Jan 2016

China To The Rescue? Implications Of Chinese Aid And Trade In Latin America Based On Evidence From Sino-African Cases, Jamie Curran

CMC Senior Theses

The rise of China is shaping developing countries around the world. The infamous Sino-African relationship has highlighted the detrimental effects of unconditional Chinese aid and trade in developing regions. Corrupt countries are now able to access large amounts of aid with “no-strings attached.” Even more, China’s hunger for natural resources has caused many African economies to increasingly rely on primary products.

Despite the extensive coverage on Sino-African relations, little light has been shed on the long-term implications of Chinese unconditional aid and trade in Latin America. However, as Latin American economies are forced to “deindustrialize” and corrupt regimes remain intact, …


Evaluation Of An Augmentative And Alternative Communication Intervention For Individuals With Aphasia., Michelle Lam Jan 2016

Evaluation Of An Augmentative And Alternative Communication Intervention For Individuals With Aphasia., Michelle Lam

CMC Senior Theses

With a large population of people who suffer from aphasia, it is imperative that an effective form of therapy is utilized. The purpose of this study was to investigate the effectiveness of augmentative and alternative communication (AAC) programs in improving the communication needs and lives of people affected by aphasia. Individuals (n = 20) suffering from aphasia for 3 months or more completed therapy sessions with speech and language pathologists and the AAC program. Pre- and post-intervention evaluations were administered, consisting of communication satisfaction and success questionnaires, the Western Aphasia Battery (WAB), and probing tests (prompt and response) with an …


Identification Of Functional Single Nucleotide Polymorphisms Associated With Breast Cancer Based On Chromatin Modifications, Laura E. Hayward Jan 2016

Identification Of Functional Single Nucleotide Polymorphisms Associated With Breast Cancer Based On Chromatin Modifications, Laura E. Hayward

CMC Senior Theses

Breast cancer affects 1 in 8 women and can be deadly; yet when detected early enough it is often treatable. Thus, early detection of breast cancer is imperative to save lives. The success of early detection depends, in part, on being able to stratify risk. A new approach to determining risk involves identifying genetic variants that alter an individual’s risk for developing breast cancer. This thesis identified key functional candidates involved in breast cancer development, some of which have been verified by other studies. For a few of the functional candidates, further research needs to be done in order to …


The Modern Administrative State: Why We Have ‘Big Government’ And How To Run And Reform Bureaucratic Organizations, Sean Y. Sakaguchi Jan 2016

The Modern Administrative State: Why We Have ‘Big Government’ And How To Run And Reform Bureaucratic Organizations, Sean Y. Sakaguchi

CMC Senior Theses

This work asserts that bureaucratic organization is not only an inevitable part of the modern administrative state, but that a high quality bureaucracy within a strongly empowered executive branch is an ideal mechanism for running government in the modern era. Beginning with a philosophical inquiry into the purpose of American government as we understand it today, this paper responds to criticisms of the role of expanded government and develops a framework for evaluating the quality of differing government structures. Following an evaluation of the current debate surrounding bureaucracies (from both proponents and critics), this thesis outlines the lessons and principles …