Digital Commons Network^™

Genomic Imbalances In Peripheral Blood Confirm The Diagnosis Of Myelodysplastic Syndrome In A Patient Presenting With Non-Immune Hemolytic Anemia, Mohammad Faizan Zahid, Nadia Khan, Jianming Pei, Joseph R. Testa, Essel Dulaimi

Medical College Documents

Myelodysplastic syndrome (MDS) is a clonal stem-cell disorder characterized by dyshematopoiesis. We report a patient who presented with cytopenias and microangiopathic hemolytic anemia. Chromosome microarray analysis (CMA), using single nucleotide polymorphism arrays, on peripheral blood revealed genomic imbalances indicative of MDS, which was confirmed by bone marrow examination. This report highlights the importance of suspecting MDS in patients with cytopenias and microangiopathic hemolytic anemia. CMA of peripheral blood may assist in the preliminary diagnosis of MDS, representing a comparatively less invasive diagnostic procedure and may aid bone marrow evaluation when an aspirate sample is insufficient for conventional cytogenetic analysis.

Depression And Anxiety: A Snapshot Of The Situation In Pakistan, Bilaal Ahmed, Syed Faaiz Enam, Zafar Iqbal, Ghulam Murtaza, Shahid Bashir

Medical College Documents

Background: Depression is a great cause of morbidity around the world. Not one person seems to escape the hollow dread that the disease can bring forth.
Aims: Although living in a large extended family which serves as a social support is common in Pakistan, why we still suffer from anxiety and depression just as often if not more than those in other countries?
Method: We checked studies conducted in different localities of Pakistan over the past 10 years to find prevalence values of anxiety and depression. Results: The values of anxiety and depression ranging from 22% to as high as …

Evaluation Of The Uptake And Impact Of Neonatal Vitamin A Supplementation Delivered Through The Lady Health Worker Programme On Neonatal And Infant Morbidity And Mortality In Rural Pakistan: An Effectiveness Trial, Sajid Soofi, Shabina Ariff, Kamran Sadiq, Atif Habib, Zaid Bhatti, Imran Ahmad, Masawar Hussain, Nabeela Ali, Simon Cousens, Zulfiqar A Bhutta

Department of Paediatrics and Child Health

Background: Despite evidence for the benefits of vitamin A supplementation (VAS) among children 6 to 59 months of age, the feasibility of introduction and potential benefit of VAS in the neonatal period in public health programmes is uncertain. Objective: The primary objective was to evaluate the feasibility and effectiveness of early neonatal VAS (single dose of 50 000 international units within 48–72 hours after birth) delivered through the public sector Lady Health Worker (LHW) programme in rural Pakistan and to document its association with a reduction in mortality at 6 months of age.
Methods: A community-based, cluster randomised, …

Activation Of Signal Transduction Pathways During Hepatic Oncogenesis, W Chung, M Kim, S De La Monte, L Longato, R Carlson, B L. Slagle, X Dong, J R. Wands

Faculty, Staff and Students Publications

BACKGROUND AND AIMS: Understanding the molecular pathogenesis of hepatocellular carcinoma (HCC) is essential to identify therapeutic targets. A hepatitis B virus (HBV) related double transgenic murine model was developed. METHODS: Liver specific expression of HBV X protein (HBx) and insulin receptor substrate 1 (IRS1) was achieved and transgenic mice were followed from birth to age 21 months. Liver and tumor tissue were assessed for histologic changes as well as activation of signal transduction pathways by qRT-PCR and multiplex ELISA protein assays. RESULTS: Overexpression of HBx and IRS1 stimulates liver cell proliferation in the double transgenic mice. Only the male mice …

African Masks From The Collection Of James Gaasch, James Gaasch

Trade & Scholarly Monographs

African Masks from the Collection of James Gaasch contains photographs of the African masks and carvers from the Bwa (or Bwaba), Winiama and Mossi peoples of Burkina Faso, and the Bamana and Dogon peoples of Mali. Gaasch acquired many of these masks in the villages where they were carved. When possible, he interviewed the village carvers, the creators, of these dancing masks. Gaasch’s interviews with the carvers underscore the cultural context where traditional African world views persist. And, to the extent possible, they give voice to the masks to reveal their own significance. “They are, in our times, signifiers of …

Absence, Revision, And The Other: Rhetorics Of South Carolina Antebellum Tourism Sites, Deborah Cunningham Breede, Christine S. Davis, Jan Warren-Findlow

Journal of Hate Studies

The production of tourism situated within an antebellum history is fraught with tension. Moralities, power conflicts, and identities clash as tourist production based on historical apartheid in the United States proliferates and becomes more popular and profitable. Southern states such as South Carolina are particularly subject to such concerns. As one of the original thirteen colonies, South Carolina was a profitable participant in the plantation system, a system built upon rhetorics of absence, revision, and hatred. These rhetorical constructions effectively created a view of enslaved Africans that “othered” and minimized them and erased their presence, importance, and humanity. The resulting …

Curating Hatred: The Joe Mcwilliams's Controversy At The Ulster Museum, Tom Maguire

Journal of Hate Studies

Since heritage is a manifestation of how the past is used in the present,engagement with heritage is a critical indicator of how contemporaryhatreds play out, both feeding and feeding off traditions and legacies.Despite its ongoing peace process, Northern Ireland remains a site of dissonantheritages, where sectarian hatred continues to be expressed in societaldivisions, often resulting in outright violence. This relationship betweencurrent expressions of hatred and the uses of the past present particularissues for heritage professionals. This essay examines a recent example inwhich these tensions have been made manifest, the inclusion of a paintingby Belfast artist Joe McWilliams in the Annual …

Discussing Auschwitz, Scholarly Integrity And Governmental Revisionism: A Case Study In Academic Intimidation, Kevin Mccarthy

Journal of Hate Studies

In September 2015, I became embroiled in a controversial and confrontational media discourse that rapidly assumed a global context as external actors engaged in a hateful campaign of intimidation and threatening behavior. It was initiated by a letter I had published in the Belfast Telegraph, which included a reference that localised anti-Semitism was a factor in the Nazi decision to locate the Auschwitz-Birkinau extermination camp in Poland. It was a response to a letter thread that had included multiple mentions of Poland, Auschwitz-Birkinau, and hateful intimidation. However, a forensic examination of the letter suggests the confrontation had, in fact nothing …

Elements Of Bile: Placing Daniel Ottolengui (1836-1918) In The Heritage Of Hate, Sally Stokes

Journal of Hate Studies

Just east of Broadway, in 1846, Isaac D. Baker and Charles Scribner opened their publishing house on Nassau Street near Ann Street in lower Manhattan. By the time of the Civil War, Baker & Scribner had cemented a reputation for thoughtful and elevating texts. In 1867, the firm, now Charles Scribner & Co., having moved up to 654 Broadway and released a miscellany of Christian meditations, poetry by Robert Burns, and a translation of the Iliad, had picked up Henry Ward Beecher’s Norwood, or Village Life in New England. This lone novel by Beecher—orator, abolitionist, and minister of Brooklyn’s Plymouth …

Comparative Analysis Of Female And Male Coverage On Espn’S Sportscenter, Tywan G. Martin, Young Ik Suh, Antonio S. Williams, Jennifer Locey, Jennifer Ramirez

Global Sport Business Journal

The purpose of this study was to examine whether gender differences existed in the coverage on ESPN’s flagship program, SportsCenter. This study was grounded in the theoretical frameworks of hegemony and agenda setting. The researchers collected data over the course of seven days during the 11:00 p.m. show. A comparative analysis was performed on the content of the popular one-hour television program that investigated the amount of coverage devoted to female and male sports, respectively. The findings of the study indicated that there was a statistically significant difference between the amount of highlights devoted to female athletes in comparison to …

A Delphi Method Analysis Of Management Strategies For Taekwondo Centers In The United States, Jinsun Han, Sungick Min, Jaeyeon Hwang, Penny Dalton Hite, Wonyul Bae

Global Sport Business Journal

The purpose of this study was to use the Delphi Method to determine management strategies that might enhance the operations of Taekwondo training centers in the US and; to induce management to implement the strategies based on that forecast. A sample of ten Korean masters and fifteen trainers were used in this inquiry. Each participant has an interest in a Taekwondo facility, more than three years of teaching experience and has been practicing Taekwondo for more than ten years. This study followed the protocols for the Delphi Method and consisted of three phases of data collection using questionnaires. The panel …

Football Bowl Subdivision Head Football Coaches’ Contracts: An Analysis Of Contractual Clauses In Intercollegiate Athletics, R. Christopher Reynolds, Paul M. Pedersen

Global Sport Business Journal

While many studies have been published on a variety of sport law topics, only a handful of scholars have contributed to the body of knowledge on issues related to college coaches’ contracts. The current study examines the “state of the art” of college coaches’ contracts using the content analytic method. All clauses included in the employment contracts (N=91) of head football coaches at Football Bowl Subdivision (FBS) schools were examined and coded in an effort to discover the essential, consistent, and unique components of the coaches’ contracts. A total of 30 clauses were identified and coded. The study found that …

Assessing The Effect Of Family Structure On Perceptions Of Fan-Family Conflict, Jason M. Simmons, T. Christopher Greenwell, Thomas J. Aicher

Global Sport Business Journal

Fan-family conflict refers to the difficulty experienced fulfilling family role demands as a result of fan role participation. Prior research suggests team identification leads to higher fan-family conflict as a result of the resources devoted to one’s fan role (i.e. time, money, energy), strain associated with maintaining a positive social identity, and incompatible behaviors commonly liked to fan role engagement (Simmons & Greenwell, 2014). The current study sought to understand how family role demands impact perceptions of fan-family conflict, specifically, how perceptions of fan-family conflict vary based on family structure. Results of this study challenge our understanding of this effect, …

Profiling The Sports Blogosphere, Charlotte Allen, Jason D. Reese

Global Sport Business Journal

The purpose of this study is to provide primary research regarding how sports blogs utilize the social media and generate revenue for their blog. This study begins with a literature review of the blogging world with a special emphasis on the sports sector of the blogosphere. The literature review is followed by a discussion of the research method of content analysis, which was employed to examine the selected sports blogs. Furthermore, recommendations are made concerning sampling methods and how future statistical sampling of the sports blogosphere could proceed to improve the representativeness of samples and data collection in this research …

Generation Multitasker: How Millennials Use Second Screens While Watching Televised Sport, Ryan Vooris, Kerry Fischer, Chase M. L. Smith, Rebecca M. Achen

Global Sport Business Journal

People born between 1980 and 2000 are commonly known as the Millennial generation (Gurau, 2012). Millennials are digital natives of a 24/7 online, there’s an app for everything, social media-rich landscape in which older generations will always be, to some degree, foreigners. Through the use of a survey, this study examined how a sample of 303 Millennials use mobile devices such as a smartphone or tablet to text, utilize mobile apps, and check social media while watching sport on TV. Their responses indicated the importance of using a second screen to pass the time during commercial breaks and stay informed …

2016 Gsba Conference Abstracts, Gsba

Global Sport Business Journal

No abstract provided.

Effect Of Two-Year Caloric Restriction On Bone Metabolism And Bone Mineral Density In Non-Obese Younger Adults: A Randomized Clinical Trial, Dt Villareal, L Fontana, Sk Das, Et Al.

Faculty, Staff and Students Publications

Although caloric restriction (CR) could delay biologic aging in humans, it is unclear if this would occur at the cost of significant bone loss. We evaluated the effect of prolonged CR on bone metabolism and bone mineral density (BMD) in healthy younger adults. Two-hundred eighteen non-obese (body mass index [BMI] 25.1?±?1.7?kg/m(2) ), younger (age 37.9?±?7.2 years) adults were randomly assigned to 25% CR (CR group, n?=?143) or ad libitum (AL group, n?=?75) for 2 years. Main outcomes were BMD and markers of bone turnover. Other outcomes included body composition, bone-active hormones, nutrient intake, and physical activity. Body weight (-7.5?±?0.4 versus …

Geospatial Analysis Of Food Environment Demonstrates Associations With Gestational Diabetes, Mk Kahr, Ma Suter, J Ballas, Sm Monga, W Lee, M Hu, Cd Shope, A Chesnokova, L Krannich, En Griffin, J Mastrobattista, Ga Dildy, Sl Strehlow, R Ramphul, Et Al.

Faculty, Staff and Students Publications

BACKGROUND: Gestational diabetes mellitus (GDM) is one of most common complications of pregnancy, with incidence rates varying by maternal age, race/ethnicity, obesity, parity, and family history. Given its increasing prevalence in recent decades, covariant environmental and sociodemographic factors may be additional determinants of GDM occurrence. OBJECTIVE: We hypothesized that environmental risk factors, in particular measures of the food environment, may be a diabetes contributor. We employed geospatial modeling in a populous US county to characterize the association of the relative availability of fast food restaurants and supermarkets to GDM. STUDY DESIGN: Utilizing a perinatal database with >4900 encoded antenatal and …

Identification Of A Novel Gene On 10q221 Causing Autosomal Dominant Retinitis Pigmentosa (Adrp), Stephen P Daiger, Lori S Sullivan, Sara J Bowne, Daniel C Koboldt, Susan H Blanton, Dianna K Wheaton, Cheryl E Avery, Elizabeth D Cadena, Robert K Koenekoop, Robert S Fulton, Richard K Wilson, George M Weinstock, Richard A Lewis, David G Birch

Faculty, Staff and Students Publications

Whole-genome linkage mapping identified a region on chromosome 10q21.3-q22.1 with a maximum LOD score of 3.0 at 0 % recombination in a six-generation family with autosomal dominant retinitis pigmentosa (adRP). All known adRP genes and X-linked RP genes were excluded in the family by a combination of methods. Whole-exome next-generation sequencing revealed a missense mutation in hexokinase 1, HK1 c.2539G > A, p.Glu847Lys, tracking with disease in all affected family members. One severely-affected male is homozygous for this region by linkage analysis and has two copies of the mutation. No other potential mutations were detected in the linkage region nor were …

Local Corticotropin Releasing Hormone (Crh) Signals To Its Receptor Crhr1 During Postnatal Development Of The Mouse Olfactory Bulb, Isabella Garcia, Paramjit K Bhullar, Burak Tepe, Joshua Ortiz-Guzman, Longwen Huang, Alexander M Herman, Lesley Chaboub, Benjamin Deneen, Nicholas J Justice, Benjamin R Arenkiel

Faculty, Staff and Students Publications

Neuropeptides play important physiological functions during distinct behaviors such as arousal, learning, memory, and reproduction. However, the role of local, extrahypothalamic neuropeptide signaling in shaping synapse formation and neuronal plasticity in the brain is not well understood. Here, we characterize the spatiotemporal expression profile of the neuropeptide corticotropin-releasing hormone (CRH) and its receptor CRHR1 in the mouse OB throughout development. We found that CRH-expressing interneurons are present in the external plexiform layer, that its cognate receptor is expressed by granule cells, and show that both CRH and CRHR1 expression enriches in the postnatal period when olfaction becomes important towards olfactory-related …

2016 Outlook And Analysis Letter, A Report Prepared For The National Association Of State Park Directors, Jordan W. Smith, Yu-Fai Leung

All Current Publications

This report evaluates both the production of outdoor recreation opportunities at, and the operational efficiency of, the nation’s state park systems.

Asia Pacific Perspectives Vol. 13 No. 2, Fall/Winter 2015-2016, University Of San Francisco

Asia Pacific Perspectives

Contents:

Editor's Introduction by Melissa Dale

Small Things of Great Importance: Toy Advertising in China, 1910s-1930s by Valentina Boretti

From the turn of the twentieth century, playthings acquired a key role within the Chinese childrearing discourse as tools to train children, the prospective rescuers of China from its perceived decline. As a possibly unintended result, both children and toys acquired a marketing value: advertising employed them as icons to publicize a wide array of products. At the same time, the nascent toy industry “poached” the new discourse to brand its playthings as symbols of (made-in-China) educated progress, seeking to convince …

Asia Pacific Perspectives Vol. 14 No. 1, Fall 2016, University Of San Francisco

Asia Pacific Perspectives

Contents:

Editor's Introduction by Melissa Dale

This special issue presents five papers focused on themes related to the social history of medicine and contemporary cultural understandings of disease and patients' lived experiences in the Asia Pacific.

Rethinking Breast Mountain (Yuam): Surgical Treatments of Breast Cancer in South Korea, 1959-1993 by Soyoung Suh

This article analyzes premodern Korean medical treatises, professional surgical journals, and patient memoirs to expand our understanding of surgical treatment of breast cancer between 1959 and 1993 in South Korea. This essay discusses changing historical connotations of breast ailments, treatments, and surgical interventions. Although the depiction of breast …

La Diabetes Y La Alimentación Determinantes En La Progresión De Aterosclerosis, Adriana Leticia Perales-Torres, Octelina Castillo-Ruíz, María Teresa Castañeda Licón, Sanjuana E. Alemán-Castillo, Juan Miguel Jiménez Andrade

Health & Biomedical Sciences Faculty Publications

El propósito de esta revisión es analizar la progresión bioquímica de la placa aterosclerótica y la relación que presenta con la diabetes y la alimentación. Se exponen las evidencias científicas de pacientes con diabetes, que a diferencia de pacientes no diabéticos presentan niveles más elevados de algunos ácidos grasos en la placa de ateroma (como el palmítico, linoleico y oleico), elevada incidencia de trombosis coronaria relacionada con el incremento en el tama˜no de la base necrótica y la disminución del tama˜no de la capa fibrosa de los ateromas. Entre ambos grupos de pacientes se expone la diferencia en el perfil …

Boundedly Rational Entrepreneurs And Antitrust, Avishalom Tor

Journal Articles

This article examines entrepreneurial activity and its implication for policy and antitrust law from a behavioral perspective. In particular, the analysis here focuses on the role of two sets of behavioral phenomena—overconfident beliefs and risk-seeking preferences—in facilitating boundedly rational entrepreneurship. Boundedly rational entrepreneurs may engage in entrepreneurial activity, such as the starting of new business ventures, under circumstances in which rational entrepreneurs would decline to do so. Consequently, overconfident or risk-seeking entrants compete with their more rational counterparts and create a post-entry landscape that differs markedly from the picture assumed by traditional economic accounts of entrepreneurial activity. The behaviorally informed …

University Of San Diego Graduate Course Catalog 2016-2017, University Of San Diego

Graduate Course Catalogs (1971-)

190 pages

Creativity And Illness: An Anecdotal Exploration Of A Writing Practice; Coming Undone: A Collection Of Poems & A Thesis As An Anecdotal Exploration Of A Writing Practice, Matthew Patrick Roberts

Theses: Doctorates and Masters

This thesis combines both creative and critical writing in an exploration of creativity and illness. When I began my candidature, I started writing a novel but found with the diagnosis of chronic illness I could no longer write narrative and was irresistibly drawn to poetry.

The collection of poems was written during the period immediately following the diagnosis of, and during my subsequently living with, a chronic autoimmune illness, and is an expression of the lived experience of both being ill and being a writer. The poems have been separated into three chronological parts, each reflective of the emotional changes …

Analysis Of Right-Turn Lane Length In Left-Hand Traffic Countries At Signalised Intersections Of Urban Roads, Noura Thomas

Theses: Doctorates and Masters

Analysis of the right turn lane length of urban roads in left-hand traffic countries, such as Australia, UK and India (left-turn lane length in right-hand traffic countries such as USA), at signalised intersections encounters two main geometric features namely, deceleration length and storage length. The literature shows that in routine practice, the deceleration length is generally estimated by using constant deceleration rate. Many researchers consider this assumption for all design speeds unrealistic as it does not reflect the influence of the pavement condition. Hence, it may be desirable to consider the pavement’s condition in terms of its longitudinal coefficient of …

Utilising Voice Recognition Software To Improve Reading Fluency Of Struggling Adolescent Readers, Peter Count

Theses: Doctorates and Masters

Approximately 15-20% of secondary students in Australia experience reading difficulties. For many, the cognitive effort required to decode words or the lack of automaticity in the elements that contribute to fluent reading prevents effective reading comprehension. Because reading comprehension is of critical importance across the curriculum, students with difficulties in this area are at significant academic risk.

One effective method of improving reading fluency is ‘repeated readings’ (NICHHD, 2000). The purpose of this study was to examine whether the use of repeated readings delivered via a home-based program employing voice recognition software (VRS) could improve the reading fluency and self-perception …

Speaking Back To Theory: Community Development Practices In The South West Region Of Western Australia, Colleen Mary Carlon

Theses: Doctorates and Masters

This thesis explores how everyday knowledge of community development practices can inform the theorising of community development in Australia. The literature of community development offers a rich source for understanding and explaining the tensions and dilemmas of collective endeavour in context, yet arguments for particular approaches to community development can serve to evaluate practice in context. In this research, however, case studies are positioned as a source of knowledge. The power of case studies lies in their ability to portray collective action and collective action is what differentiates community development from other approaches to problems. The capacity to work in …