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Baylisascaris Procyonis Exposure Case Study, Andrea M. Lauffer M.D., Patricia Lutz M.D., Susan L. Flesher M.D.

Pediatrics

We report a case of exposure to raccoon feces found to be contaminated with baylisascaris procyonis. The exposure was recognized early enough by the family to allow prophylaxis with albendazole. Because of the potential fatal or neurologically catastrophic effects of this disease immediate treatment is indicated. This is started in advance of environmental studies that are done to determine if the feces is indeed contaminated.

Multipoint Genome-Wide Linkage Scan For Nonword Repetition In A Multigenerational Family Further Supports Chromosome 13q As A Locus For Verbal Trait Disorders, D. T. Truong, L. D. Shriberg, S. D. Smith, K. L. Chapman, A. R. Scheer-Cohen, M. M.C. Demille, A. K. Adams, Alejandro Q. Nato Jr., E. M. Wijsman, J. D. Eicher, J. R. Gruen

Biochemistry and Microbiology

Verbal trait disorders encompass a wide range of conditions and are marked by deficits in five domains that impair a person’s ability to communicate: speech, language, reading, spelling, and writing. Nonword repetition is a robust endophenotype for verbal trait disorders that is sensitive to cognitive processes critical to verbal development, including auditory processing, phonological working memory, and motor planning and programming. In the present study, we present a six-generation extended pedigree with a history of verbal trait disorders. Using genome-wide multipoint variance component linkage analysis of nonword repetition, we identified a region spanning chromosome 13q14–q21 with LOD = 4.45 between …

Ua12/2/1 College Heights Herald, Vol. 92, No. 26, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Kast, Monica. Some WKU Donors Kept Confidential by Foundations – WKU Foundation, College Heights Foundation
• Ares, Nicole. Records Denial Appeal Filed to Attorney General – Title IX
• Keltner, Bryson. International Students Share WKU Experience – Ali Alessa, Eunyoung Hayley Choi
• King, Jennifer. Editorial Cartoon re: Chestnuts Roasting
• Ho Ho Herald: College Heights Herald 2016 Christmas Gifts
• Henderson, Andrew. Look Above to the Stars for Final Week Woes
• Miller, Callie. Culture Series Attracts Expensive Speakers – Cultural Enhancement Series
• Collins, Emma. Preston Health & Activities Center …

Creating Tomorrow, Fall 2016, College Of Engineering

College of Engineering Magazines

Annual magazine for the College of Engineering at Utah State University.

Detection Of Α-Thalassemia By Using Multiplex Ligation-Dependent Probe Amplification As An Additional Method For Rare Mutations In Southern Turkey, Ozge Ozalp Yuregir, Akif Ayaz, Sinem Yalcintepe, Sezin Canbek, Didar Yanardag Acik, Basak Taburoglu Yilmaz, Tugce B. Balci

Paediatrics Publications

α-thalassemia is the most common single gene disorder in the Cukurova Region in Turkey. It is therefore routinely screened, including premaritally, in our region. The heterogeneous molecular basis of the disease makes α-thalassemia mutation detection difficult and complex. Besides well established methods, multiplex ligation dependent probe amplification (MLPA) is known as an effective, simple and specific method for the detection and characterization of deletions and duplications. We employed MLPA testing to 30 patients with hematological parameters suggestive of α-thalassemia carrier status but was negative for α-thalassemia with conventional reverse dot blot hybridization (RDB). We found α-globin gene deletions in 3 …

Can The New Ckd-Epi Btp-B2m Formula Be Applied In Children?, Guido Filler, Ana Catalina Alvarez-Elías, Katherine D. Westreich, Shih Han S. Huang, Robert M. Lindsay

Paediatrics Publications

Although measuring creatinine to determine kidney function is currently the clinical standard, new markers such as beta-trace protein (BTP) and beta-2-microglobulin (B2M) are being investigated in an effort to measure glomerular filtration rate more accurately. In their recent publication, Inker et al. (Am J Kidney Dis 2015; 67:40–48) explored the use of these two relatively new markers in combination with some commonly available clinical characteristics in a large cohort of adults with chronic kidney disease. Their research led them to develop three formulae using BTP, B2M, and a combination of the two. The combined formula is particularly attractive as it …

Atp2c2 Is Transcribed From A Unique Transcriptional Start Site In Mouse Pancreatic Acinar Cells, Melissa A. Fenech, Caitlin M. Sullivan, Lucimar T. Ferreira, Rashid Mehmood, William A. Macdonald, Peter B. Stathopulos, Christopher L. Pin

Paediatrics Publications

Proper regulation of cytosolic Ca2+ is critical for pancreatic acinar cell function. Disruptions in normal Ca2+ concentrations affect numerous cellular functions and are associated with pancreatitis. Membrane pumps and channels regulate cytosolic Ca2+ homeostasis by promoting rapid Ca2+ movement. Determining how expression of Ca2+ modulators is regulated and the cellular alterations that occur upon changes in expression can provide insight into initiating events of pancreatitis. The goal of this study was to delineate the gene structure and regulation of a novel pancreas-specific isoform for Secretory Pathway Ca2+ ATPase 2 (termed SPCA2C), which is encoded from the Atp2c2 gene. Using Next …

Pregnant Women's Perceptions Of Exposure To Brominated Flame Retardants, A. Lane, C. G. Goodyer, F. Rab, J. M. Ashley, S. Sharma, A. Hodgson, J. Nisker

Paediatrics Publications

Background: Recent media reports on human studies associating brominated flame retardants (BFRs) in household products in pregnancy with urogenital anomalies in boys and endocrine disruption in both sexes. We sought to explore the perceptions of pregnant women of brominated flame retardant (BFR) exposure, in light of recent media reports on the adverse health effects of BFR exposure prenatally. Methods: Pregnant women were recruited for interviews through posters and pamphlets in prenatal clinics, prenatal fairs and community centres. Interviews were audiotaped and transcribed verbatim for Charmaz-based qualitative analysis supported by NVIVO 10™. Results: Theoretical sufficiency was reached after analyzing the interviews …

The Association Between Social Cohesion And Physical Activity In Canada: A Multilevel Analysis, Calvin Yip, Sisira Sarma, Piotr Wilk

Paediatrics Publications

Although previous research has shown that social cohesion may promote physical activity, social cohesion at the individual level was not always differentiated from social cohesion at the community level, and studies were often limited to specific population subgroups or geographical areas. We addressed the above limitations through the use of a multilevel modelling approach and nationally-representative data from the 2009–2014 Canadian Community Health Survey. Physical activity level was operationalized as average daily energy expenditure; social cohesion was assessed by self-rated sense of belonging to the local community; and communities were represented by Canada's Forward Sortation Areas. The sample included 245,150 …

Staying Current In Your Field Of Interest: Tips For Aspiring Students As Researchers, Dor D. Abelman

Health Studies Publications

Undergraduate students are becoming increasingly involved in research. They already posses the skills required to make meaningful contributions to their field of interest. Some important components of their success relates to a student's ability to stay up to date in the research of their field, and to learn practical skills pertaining to the publishing process. This article hopes to help with this through presenting easy-to-follow summary tables and short paragraphs on tips for success. Topics include staying up to date in a practical way, getting involved, reaching out for help, and publication. For students, by students, this report is relatable …

Five-Year Publication Rate Of Clinical Presentations At The Open And Closed American Shoulder And Elbow Surgeons Annual Meeting From 2005–2010, J. Kay, M. Memon, D. De Sa, A. Duong, N. Simunovic, G. S. Athwal, O. R. Ayeni

Bone and Joint Institute

© 2016, The Author(s). Background: The purpose of this study was to evaluate the five-year publication rate of papers presented at both the open and closed American Shoulder and Elbow Surgeons’ (ASES) annual meetings from 2005 to 2010. Methods: Online abstracts of the presentations at the open and closed ASES annual meetings were independently screened for clinical studies and graded for quality using level of evidence. The databases PubMed (MEDLINE), Ovid (MEDLINE), and EMBASE were comprehensively searched for full-text publications corresponding to these presentations and any paper published within five years of the presentation date was counted. Results: Overall, 131/266 …

Quantitative Computed Tomography (Qct) Derived Bone Mineral Density (Bmd) In Finite Element Studies: A Review Of The Literature, Nikolas K. Knowles, Jacob M. Reeves, Louis M. Ferreira

Bone and Joint Institute

© 2016, The Author(s). Background: Finite element modeling of human bone provides a powerful tool to evaluate a wide variety of outcomes in a highly repeatable and parametric manner. These models are most often derived from computed tomography data, with mechanical properties related to bone mineral density (BMD) from the x-ray energy attenuation provided from this data. To increase accuracy, many researchers report the use of quantitative computed tomography (QCT), in which a calibration phantom is used during image acquisition to improve the estimation of BMD. Since model accuracy is dependent on the methods used in the calculation of BMD …

A Validated Software Application To Measure Fiber Organization In Soft Tissue, Erica E. Morrill, Azamat N. Tulepbergenov, Christina J. Stender, Roshani Lamichhane, Raquel J. Brown, Trevor J. Lujan

Mechanical and Biomedical Engineering Faculty Publications and Presentations

The mechanical behavior of soft connective tissue is governed by a dense network of fibrillar proteins in the extracellular matrix. Characterization of this fibrous network requires the accurate extraction of descriptive structural parameters from imaging data, including fiber dispersion and mean fiber orientation. Common methods to quantify fiber parameters include fast Fourier transforms (FFT) and structure tensors, however, information is limited on the accuracy of these methods. In this study, we compared these two methods using test images of fiber networks with varying topology. The FFT method with a band-pass filter was the most accurate, with an error of 0.71 …

Scholarworks Statistics - December 2016, Scholarworks

ScholarWorks Reports

For the month of December 2016, ScholarWorks recorded a total of 22,082 full-text and additional file downloads and 8,009 page views.

Deaf Catholic Newsletter, Advent-Christmas 2016

Deaf Catholic Newsletter

A newsletter published for Deaf Catholics in Philapelphia, PA

Deaf Catholic Newsletter Finding Aid

In The Postoperative Cardiothoracic Surgical Patient Being Mechanically Ventilated, Is There A Difference In Outcomes When Comparing Sedation With Dexmedetomidine Versus Propofol?, Benjamin Heinrich Riebesel

Doctoral Projects

Patients undergoing a cardiothoracic operation typically require mechanical ventilation in the postoperative phase. Each year approximately 395,000 of these operations are performed in the United States alone. As many as 10% of these patients require reoperation within the first few hours of recovery due to complications (Barash & Cullen, 2013). This comprehensive review of the literature was performed to determine whether postoperative sedation with dexmedetomidine leads to better patient outcomes than sedation with propofol. Inclusion criteria included publications written in the English language, articles available in full text, articles written within the last 10 years, and publications with a focus …

Parturient Safety: Proper Positioning Education Prior To Neuraxial Anesthesia, Christina Joy Young

Doctoral Projects

In the United States, 61% of parturient patients elect neuraxial anesthesia for labor pain (Koyyalamudi et al., 2016). The incidence of postdural puncture headache is estimated up to 81% following accidental dural puncture-especially in pregnant women receiving elective epidurals (Ragab & Facharzt, 2014). Although the combined rates of complications for spinal and epidural anesthesia are low (2.78%) (American Society Anesthesiologists, 2014), patient safety is extremely important and should be addressed by the overall healthcare system. The purpose of this project assessed a willingness to change which focused on the CRNAs incorporation of proper positioning education prior to neuraxial anesthesia into …

The Effects Of Tranexamic Acid On Mortality Rate In Trauma Patients Compared To Trauma Patients With No Tranexamic Acid Treatment, Bradley Earl Tolar

Doctoral Projects

Traumatic injury is the leading cause of death for many age groups. Traumatic accidents caused over 130,000 deaths in the United States in 2014. This DNP project studied the effects of Tranexamic acid on mortality rate in trauma patients. After the completion of a needs assessment at a local level II trauma center, a literature review was performed. The literature showed a decrease in mortality rate when patients were administered Tranexamic acid within 3 hours of injury with statistically significant statistics. Also, the data from the literature showed no correlation between vascular occlusive events and Tranexamic acid use in trauma …

Electronic Communication Among Anesthesia Providers, Joseph K. Wells

Doctoral Projects

Facilities in the United States are utilizing electronic communication devices (ECDs) for their nursing staff on intensive care units, general medical-surgical floors, and chemotherapy floors, but it is underutilized in the operating room where seconds truly matter (Wu et al., 2012). Situations arise daily within operating rooms that require quick and decisive communication to avoid poor patient outcomes. The ultimate goal is to prevent poor patient outcomes by enhancing communication among anesthesia providers.

This doctoral project evaluated an anesthesia group in southeast Mississippi regarding their satisfaction with current devices used for communication. This anesthesia group utilized smart phones and public …

Adoption Of Perioperative Lidocaine Infusion For The Reduction Of Postoperative Pain, Brandon Scott Figueiredo

Doctoral Projects

Laparoscopic capability provides numerous benefits to patients requiring abdominal surgical procedures. However, the use of these techniques has presented the anesthesia provider with a unique set of challenges in terms of perioperative management and postoperative pain reduction. No standardized method has existed to reduce postoperative pain and improve recovery following these procedures. There were three primary goals of this project. The first goal was to conduct a meta-analysis of randomized controlled trials to determine the benefit of the use of intravenous lidocaine infusions to reduce postoperative pain in laparoscopic abdominal surgery. Twelve articles were included in the meta-analysis that pertained …

The Use Of Simulation To Decrease Stress In First Year Student Registered Nurse Anesthetists, Jared Scott Seymour

Doctoral Projects

Each year, critical care nurses across the nation make the decision to become anesthesia providers. In order to become a certified anesthesia provider, nurses must meet the high standards required to be considered for entrance into anesthesia school. Once accepted, these students, known as Student Registered Nurse Anesthetists (SRNAs), must successfully complete a rigorous curriculum consisting of both didactic and clinical training. Due in part to the high degree of difficulty of anesthesia programs, SRNAs are at risk for experiencing high levels of stress. Chipas and McKenna (2011) shows SRNAs experience a self-reported average daily stress level of 7.2 on …

Is Current Evidence That Avoidance Of Inhalation Agents And Opioids May Decrease Metastasis Strong Enough For Crnas To Show A Willingness To Change Practice?, Michael Wesley Tillman

Doctoral Projects

Metastasis following the surgical resection of primary site breast cancer is a medical issue, which plagues mastectomy patients. The intention of this project was to synthesize current literature in order to make a presentation and disseminate it to Certified Registered Nurse Anesthetists (CRNAs) in southern Mississippi and assess the providers' willingness to change practice. CRNAs took part in a Qualtrics survey after viewing a PowerPoint presentation of evidence regarding anesthesia and metastasis. The presentation illustrated the anesthetic techniques and pharmacological agents utilized, which either mitigate or potentiate a patient's risk for metastasis. The survey assessed for a willingness to change …

Fentanyl Administration On Emergence From Surgery And Post Anesthesia Care Unit Discharge Times And Pain Scores, Andrew Ernst Wetzel

Doctoral Projects

Problem: Pain has been historically mismanaged potentially leading to a host of negative physiological consequences. Today’s dynamic health care reform offers an opportunity to increase satisfaction with care. Utilizing the PICO question, in adults undergoing laparoscopic cholecystectomy over a 12 month period, does medication with fentanyl during emergence versus not medicating during emergence reduce the need for pain medications and discharge times? Evidence/Background: Two national studies surveyed patient perception of pain management following surgery. The first, conducted by Apfelbaum et.al (2003) showed that 80% of patients experienced acute pain after surgery with 86% rating that pain as moderate …

A Comparison Of The Features And Functions Available In Electronic Health Records, Kathryn Marie Tetreault

Doctoral Projects

The Institute of Medicine (IOM) (2007) estimates that medical errors transpire at a rate of 1.5 million per year. The IOM (2000), approximates 7,000 deaths per year are related to preventable medication errors, which are the leading cause of medical errors. Adverse drug events (ADE) occur due to medication errors, which are 100% preventable. Annually, approximately $21 billion dollars are spent to care for patients’ who experience ADE due to medication errors (IOM, 2007).

This doctoral project evaluates the current features and available functions for pediatric medication administration within the electronic health record (EHR). This comparison explored the EHR functionalities …

Use Of A Handoff Communication Tool Between Certified Registered Nurse Anesthetists, Anesthesiologists, And Post Anesthesia Care Unit Nurses, Rachel Louise Johnson

Doctoral Projects

Ineffective communication in the post-anesthesia care unit (PACU) is considered to have incidences of increased error, mortality, morbidity, which leads to decrease patient outcomes and quality of care. Therefore, the purpose of this study was to introduce a structured, standardized, and consistent handoff tool to Certified Registered Nurse Anesthetists (CRNA), Anesthesiologists, and Post Anesthesia Care Unit Nurses (PACU) that may result in favorable perception of usage. Without a structured handoff tool, the organization risks the occurrence of increasing errors when the message is not transmitted effectively and efficiently every time. Distractions leave the handoff susceptible to a breakdown during the …

Social Capital Made Visible: A Case Study Of Professional Learning Communities In Early Care And Education, Wendy Bickford Allen

Dissertations

Early care and education (ECE) services are necessary for a society because of a variety of ethical, economic, and developmental reasons. A well-developed field of practice is needed to ensure young children have access to high quality care and education settings. To promote a thriving profession, many are calling for the field of early care and education to increase the human capital, or the knowledge and skills gained through higher education and professional development, of those that work directly with young children and families. However, there exists a somewhat narrow theoretical basis for current professional development practices, particularly forms of …

An Evaluation Of Making Action Plans: The Effects On Parent Involvement In Individualized Education Program Meetings, Lauren P. Hangge

Dissertations

Over the course of extensive research, researchers have acknowledged the positive effects of parent involvement on student’s education, including positive academic and social emotional outcomes. Despite this, particularly for parents of students in special education, parents continue to be passive participants in their students Individualized Education Program meetings, and hold negative perceptions of IEP meetings, which negatively effects parent involvement. This study investigated the effects of a Making Action Plans (MAPS) meeting on parent involvement in an IEP meeting, using a non-experimental design, and qualitative analysis and multiple linear regressions to analyze research questions. Although some positive effects were noted, …

White-Nosed Coatis (Nasua Narica) As Hosts For The Endoparasite, Giardia Lamblia, December 2016, Megan Sha

Monteverde Institute: Tropical Ecology and Conservation

Giardiasis, the disease caused by the protozoan endoparasite, Giardia lamblia, has become an increasingly concerning threat to both animals and humans, especially for travelers in the form of “travelers’ diarrhea” and in developing countries such as Costa Rica. Parasitic infections are an omnipresent problem that are often a result of zoonotic diseases, or diseases that are transmitted from animal to human. This study strove to determine if white-nosed coatis (Nasua narica) could potentially be hosts to Giardia lamblia in Monteverde, similar to how they are capable of acting as hosts for other zoonoses. I collected 28 coati fecal samples at …

Alumni Journal - Volume 87, Number 3, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Features
12 | Of Checks and Recyclables
14 | Interview: Mission Trip Man, Arnold L. Petersen ’66
18 | Graduation 2016
32 | The Physician's Ode
33 | Runaway Patient
34 | Not for the Faint of Heart
36 | I'm Sorry, Not Guilty

Departments
2 | From the Editor
3 | This and That
4 | From the President
6 | From the Dean
7 | The Student Fund
8 | School of Medicine News
40 | AIMS Report
44 | Book Review
46 | Placement and Classified Ads
48 | Alumni News
49 | In Memoriam
52 | …

Cultural Sensitivity In Healthcare: The New Modern Day Medicine, Daniel Dell'osso

Senior Theses

In healthcare facilities there are many factors that contribute to overall equity, efficiency, and quality of care which if addressed properly can promote justice for all. Patients relying on healthcare facilities come from a variety of races, ethnicities, and cultures as are the employees who provide care for the patients. Diversity is very widespread within the healthcare environment and tolerance as well as acceptance of others is necessary in conducting smooth and efficient care. However, cultural sensitivity and competency seems to continue to be an issue that has been neglected and has severely negatively impacted healthcare centers and its surrounding …