Digital Commons Network^™

Seeing The Invisible: Revealing Atrial Ablation Lesions Using Hyperspectral Imaging Approach, Narine Muselimyan, Luther Swift, Huda Asfour, Tigran Chahbazian, Ramesh Mazhari, Marco Mercader, Narine Sarvazyan

Pharmacology and Physiology Faculty Publications

Background

Currently, there are limited means for high-resolution monitoring of tissue injury during radiofrequency ablation procedures.

Objective

To develop the next generation of visualization catheters that can reveal irreversible atrial muscle damage caused by ablation and identify viability gaps between the lesions.

Methods

Radiofrequency lesions were placed on the endocardial surfaces of excised human and bovine atria and left ventricles of blood perfused rat hearts. Tissue was illuminated with 365nm light and a series of images were acquired from individual spectral bands within 420-720nm range. By extracting spectral profiles of individual pixels and spectral unmixing, the relative contribution of ablated …

Population Pharmacokinetics Of Liposomal Amphotericin B In Immunocompromised Children., Jodi M Lestner, Andreas H Groll, Ghaith Aljayyoussi, Nita L Seibel, Aziza Shad, Corina Gonzalez, Lauren V Wood, Paul F Jarosinski, Thomas J Walsh, William W Hope

Pediatrics Faculty Publications

Liposomal amphotericin B (LAmB) is widely used in the treatment of invasive fungal disease (IFD) in adults and children. There are relatively limited pharmacokinetic (PK) data to inform optimal dosing in children that achieves systemic drug exposures comparable to those of adults. Our objective was to describe the pharmacokinetics of LAmB in children aged 1 to 17 years with suspected or documented IFD. Thirty-five children were treated with LAmB at doses of 2.5 to 10 mg kg(-1) daily. Samples were taken at baseline and at 0.5- to 2.0-h intervals for 24 h after receipt of the first dose (n = …

Tx-004hr Improves Sexual Function As Measured By The Female Sexual Function Index In Postmenopausal Women With Vulvar And Vaginal Atrophy: The Rejoice Trial., Sheryl A Kingsberg, Leonard Derogatis, James A Simon, Ginger D Constantine, Shelli Graham, Brian Bernick, Gina Gasper, Sebastian Mirkin

Obstetrics and Gynecology Faculty Publications

INTRODUCTION: TX-004HR is an investigational, applicator-free, vaginal soft gel capsule containing low-dose solubilized 17β-estradiol. The phase 3, randomized, double-blinded, placebo-controlled, multicenter REJOICE trial has shown TX-004HR to be safe and effective for the treatment of moderate to severe dyspareunia in postmenopausal women with vulvar and vaginal atrophy (VVA).

AIM: To evaluate the effect of TX-004HR on female sexual dysfunction in postmenopausal women with VVA.

METHODS: The REJOICE study compared the effects of 12-week treatment with TX-004HR (4, 10, or 25 μg) with placebo in postmenopausal women (40-75 years old) with VVA and a most bothersome symptom of moderate to severe …

Amaurosis Fugax Due To Pleomorphic Sarcoma, Sheila Pabon, Katherine Williams, Marena Patronas

Ophthalmology Faculty Publications

Purpose

This report describes a case of amaurosis fugax due to a rare primary cardiac sarcoma.

Observations

A patient who was recently diagnosed with left atrial pleomorphic sarcoma presented with a chief complaint of multiple episodes of intermittent vision loss in the right eye during the course of radiation therapy.

Conclusions and importance

The authors postulate emboli from the left atrial sarcoma entered systemic circulation and subsequently caused brief episodes of transient occlusion to retinal, ophthalmic and/or ciliary arteries leading to momentary retinal hypoxia. We believe this is a novel finding, previously unreported in the literature, of transient embolic occlusion …

Iris Abscess A Rare Presentation Of Intravenous Drug Abuse Associated, Jonathan Pierce, Nisha Warrier, Christina Antonopoulos, Nicole Siegel, Deeba Husain

Ophthalmology Faculty Publications

Purpose: To describe an unusual case of intravenous drug abuse associated endogenous endophthalmitis presenting with an iris abscess.

Observations: A 30-year old female with history of intravenous drug use presented with a two-week history of redness and blurry vision in the right eye. An initial diagnosis of anterior uveitis was made. However, she worsened on topical steroids and mydriatics. She was found to have a hypopyon and an iris abscess. She received broad spectrum antibiotic and antifungal treatment with voriconazole, this lead to significant clinical improvement. She was discharged on oral fluconazole and lost to follow up. The patient was …

Striving Toward Transformational Resistance: Youth Participatory Action Research In The Mathematics Classroom, Mary Candace Raygoza

Kalmanovitz School of Education Faculty Works

No abstract provided.

Roy Larson -- The Architect Of Philadelphia, Dennis L. Johnson

Swedish American Genealogist

No abstract provided.

A Mission Covenant Pastor And His Memoirs, Nils Johan Lindqvist

Swedish American Genealogist

No abstract provided.

Novel Aspects Of Drosophila Suzukii (Diptera: Drosophilidae) Biology And An Improved Method For Culturing This Invasive Species With A Modified D. Melanogaster Diet, Blair J. Sampson, Trevor Mallette, Karla M. Addesso, Oscar E. Liburd, Lindsy E. Iglesias, Stephen J. Stringer, Chris T. Werle, Donna A. Shaw, Drew Larsen, John J. Adamczyk

Agricultural and Environmental Sciences Faculty Research

Drosophila suzukii (Matsumara) (Diptera: Drosophilidae), the spotted wing drosophila, is a global pest of soft fruits now rearable on a standard D. melanogaster (Meigen) diet containing the fly's own natural food: soft-skinned berries. The techniques tested here can save 40% of cultures from microbial contamination that develops after combining artificial food sources (e.g., standard drosophila media) with unsterilized host plant material (berries). A suitable ratio for mixing dietary ingredients for a vial or test-tube rearing system includes, by weight, 1 part berry tissue for oviposition, 1.5 parts dry diet media for carbohydrate, 7 parts clean water for moisture, and ∼5 …

Bridging Anticoagulation Before Colonoscopy: Results Of A Multispecialty Clinician Survey., Geoffrey D. Barnes, Jacob Kurlander, Brian Haymart, Scott Kaatz, Sameer Saini, James B. Froehlich

Hospital Medicine Articles

No abstract provided.

Validation Of Evidence-Based Fall Prevention Programs For Adults With Intellectual And/Or Developmental Disorders: A Modified Otago Exercise Program, Mindy Oxman Renfro, Donna B. Bainbridge, Matthew Lee Smith

Health and Wellness

Introduction: Evidence-based fall prevention (EBFP) programs significantly decrease fall risk, falls, and fall-related injuries in community-dwelling older adults. To date, EBFP programs are only validated for use among people with normal cognition and, therefore, are not evidence-based for adults with intellectual and/or developmental disorders (IDD) such as Alzheimer’s disease and related dementias, cerebral vascular accident, or traumatic brain injury.

Background: Adults with IDD experience not only a higher rate of falls than their community-dwelling, cognitively intact peers but also higher rates and earlier onset of chronic diseases, also known to increase fall risk. Adults with IDD experience many barriers to …

Acting Early In Montana: Big Steps Under The Big Sky, Martin E. Blair, Ann N. Garfinkle, University Of Montana Rural Institute

Early Childhood

A collaborative effort between the UCEDD, Act Early Ambassador and 50+ provider, state agency, family and university partners in a large rural state is generating strong "Act Early Outcomes." We will describe strategic partnerships and unique approaches to encouraging awareness, early screening and diagnosis, and early intervention for autism spectrum disorders and other developmental disabilities.

A Study Of The Self-Determination Of High School Students In A Blended Learning Environment And Meeting The Goals For 21st Century Student Outcomes, Vincent Keith Wilks

Education Dissertations and Projects

The 21st century has ushered Generation Z into every educational setting. Their expectations for how, where, and how fast they learn are as diverse their world views. With the use of electronic, mobile learning devices increasing each year, there is a noted deficiency in research to provide insight into how this computer-based learning is impacting students in high schools.

In this investigation, a self-paced, internet-based instructional program is utilized by students in a brick-and-mortar location with a certified teacher as well as anywhere the student has an internet connection and a computer device.

An internet based, five-part Likert scale survey …

The Relationship Between Physical Activity Level And Perceptions Of Body Image-- A High School Female Perspective: A Convergent Parallel Mixed Methods Design, Nicole Anne Ludwa

Education Dissertations and Projects

Despite all the known social, mental, and physical benefits of physical activity, a large percentage of girls choose to engage in even less physical activity than they did as young children. Social acceptance is at its highest during the adolescent age and societal differences generated from parents, friends, and the media have created women whose general life contentment is often correlated to their perceived body image.

This mixed methods study—based on the social learning, social comparison, and feminist theories—sought to explore how physical activity level affects body image in high school females. The Physical Activity Questionnaire for Adolescents (PAQ-A; Kowalski, …

A Mixed-Methods Study Of Student Perceptions Of The Transition To Middle School, Danyah Mcallister Hill

Education Dissertations and Projects

The study detailed in this dissertation was designed to examine and understand student perceptions of self-efficacy, motivation, student-teacher relationships, and procedural differences during the transition to middle school. The mixed-methods study utilized a survey, focus groups, and interviews to triangulate the data.

An analysis of the data revealed that there is a statistically significant difference between student perceptions of motivation and self-efficacy at School A and School B. The researcher found that students at School A had a more positive perception in the areas of motivation and self-efficacy than School B, yet School B met its predicted growth score and …

Teacher Self-Efficacy, Instructional Practices, And Student Achievement In Mathematics: A Correlational Study, Kristi Lynn Day

Education Dissertations and Projects

This mixed-methods research examined teacher self-efficacy in mathematics and the use of specific mathematical instructional practices in Grades 3-5 classrooms. The purpose was to examine the relationships among teacher self-efficacy of teaching mathematics, the use of specific mathematical instructional practices, and student achievement as measured by the North Carolina end-of-grade test. According to the National Mathematics Advisory Panel (2008), differences in students’ mathematical achievement are credited to differences in teacher characteristics including their self-efficacy in teaching and use of specific instructional practices. The study sought to add to the research behind that finding.

Correlational relationships among the variables were studied. …

What Factors Help Decide To Report A Concussion Or Not, Anthony Finger

Sport Management Undergraduate

Athletes have the common issue on whether they should report a concussion or to continue to play through it. The athletes often suspect symptoms of concussions but then do not connect them to the injury concussion itself. Personal and external factors play a role in their decision making. This study looked at the St. John Fisher athletes and their decision making process on whether they report or not. The study included six football athletes and two non-football athletes, including a basketball and soccer athlete. The researcher found that athletes chose to play through their injuries and that the biggest factor …

Modelling Random Antibody Adsorption And Immunoassay Activity, Dana Mackey, Eilis Kelly, Robert Nooney

Articles

One of the primary considerations in immunoassay design is optimizing the concentration of capture antibody in order to achieve maximal antigen binding and, subsequently, improved sensitivity and limit of detection. Many immunoassay technologies involve immobilization of the antibody to solid surfaces. Antibodies are large molecules in which the position and accessibility of the antigen-binding site depend on their orientation and packing density. In this paper we propose a simple mathematical model, based on the theory known as random sequential adsorption (RSA), in order to calculate how the concentration of correctly oriented antibodies (active site exposed for subsequent reactions) evolves during …

Vol. 8 No. 1, Fall 2016; The Fatal Fiala Flaw: Hey! Why Not Just Make Arbitration Agreements Mandatory?, Adam N. Lichtenauer

Northern Illinois Law Review Supplement

This Article discusses the ability of healthcare agents to bind their principals with arbitration agreements when admitting their principals to nursing homes. A recent Illinois appellate court decision had the unfortunate effect of allowing nursing homes to expand the authority of healthcare agents to encompass arbitration agreements by simply making such agreements a requirement for admission. Although this ruling has the potential to further disadvantage people who are already unable to care for themselves, this Article will discuss approaches that can be used to correct the misstep.

Reclaming Compassion: How Compassion Moved From Virtue To Benefit, And How To Move It Back, Jon Talbert

Doctor of Ministry

This dissertation examines the growing movement of compassion that has developed and emerged in the 21st century and its impact on the current landscape of society. Section 1 takes a closer look at how compassion moved from a virtue to a benefit, and the expectation of reward that subtly crept into the developmental psyche of the culture. Section 2 traces that benefit-mentality into the seven domains of culture, including: Business, Faith, Government, Social Sector, Education, Arts & Entertainment, and the Media. Section 3 introduces a new line of thinking that reestablishes compassion to its purest form by identifying the makeup …

Design And Implementation Of A Fixture For Robotic Welding, Isaac Nathaniel Williams

Industrial and Manufacturing Engineering

The Cal Poly IME department recently purchased a robotic welder. The faculty would like to see this robot incorporated into the welding class. The robot was capable of moving, but was not able to perform a weld prior to this project. This problem is addressed by creating a demonstration part for the welding class. The objectives that need to be complete for this to be possible is designing a part, designing a fixture, analyzing the cost of robotic welding, and implement welding the part in the class. The part is designed with specific requirements in mind. The fixture is designed …

Multitaxon Distribution Models Reveal Severe Alteration In The Regional Biodiversity Of Freshwater Invertebrates, Charles P. Hawkins, Lester L. Yuan

Watershed Sciences Faculty Publications

Knowledge of current and historical conditions is needed to guide conservation and restoration policies, but such information is lacking for most taxa. This problem is especially severe for small, inconspicuous taxa, such as the thousands of invertebrate species that inhabit stream and other freshwater ecosystems. We describe a novel application of River Invertebrate Prediction and Classification System (RIVPACS)-type multitaxon distribution models that, when applied to the biological survey data routinely collected in support of water-quality monitoring programs, can quantify the regional biodiversity status of hundreds of taxa. We used models developed for 2 stream data sets (North Carolina and the …

Mole Street Journal, December 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Connections, December 2016, University Of Montana--Missoula. Mansfield Library

Connections

No abstract provided.

Military Medicine Interest Groups In U.S. Medical Schools, Timothy M. Guenther,, Maj Timothy J. Coker, Steve I. Chen, Mark A. Carlson

United States Department of Veterans Affairs: Publications

Medical student interest groups are organizations that help expose students to different medical specialties and fields of medicine while in medical school. Military medicine interest groups (MMIGs) are a particular type of interest group that spreads information about military medicine, fosters mentorship, and camaraderie between students and military faculty, and increases the opportunities for leadership while in medical school. Surveys were sent to all U.S. medical schools to determine how many schools had an MMIG. If a medical school had a group, a second survey was sent to the student leader to determine more information about how their group operated …

Socio-Demographics And Exclusive Breastfeeding In The Medicaid/Women Infant And Children (Wic) Population In Spartanburg County, April D. Miller

Nursing Theses and Capstone Projects

Breast milk is recognized as the optimal source of nutrition for infants because of its unique nutritional and immunological characteristics. The American Academy of Pediatrics recommends exclusive breastfeeding for the first six months of an infant’s life. "Exclusive breastfeeding (EBF)" is defined as no other food or drink except breast milk for the first six months of life. Despite its countless benefits to children and mothers, the continuation rates of exclusive breastfeeding are low in the United States, especially in the Medicaid/Women Infant and Children population. It is vital to understand how multiple factors affect breastfeeding practices in order to …

Nurse Preceptors' Perceptions Of Preparedness In The Preceptor Role, Ebony Phillips

Nursing Theses and Capstone Projects

Healthcare is multifaceted with complicated illnesses that require aggressive treatments and therapies. Caring for patients with these illnesses has become progressively difficult due to the nursing shortage, high turnover rates, and lack of competence and critical thinking, which impacts quality care and outcomes. To enhance the knowledge of the nurses, preceptors are an essential part the orientation experience. Therefore, preceptors’ perceptions of preparedness influence the effectiveness of the role. Appropriate preparation provides them with the knowledge needed to meet learning needs. The aim of this study was to explore preceptors’ perceptions of preparedness in the preceptor role. The perceptions of …

The Impact Of Short Papers On Clinical Decision Making Skills Of Nursing Students, Tara R. Hayes

Nursing Theses and Capstone Projects

Clinical decision making and critical thinking are fundamental skills to ensuring the success of undergraduate nursing students. Nursing faculty, and specifically clinical nursing faculty, are responsible for encouraging the development of these types of skills as students work in direct patient care. Traditional methods of clinical evaluation include lengthy case studies, concept mapping, and discussion board participation. While these methods have been in effect for some time, clinical short paper assignments are a fresh, innovative way to challenge students as they refine their critical thinking and clinical decision making abilities. No statistically significant difference was found between the perceived level …

Depression Scores In Males And Females With Copd, Cynthia Southers

Nursing Theses and Capstone Projects

The purpose of this study was to determine the effect of participation in a pulmonary rehabilitation (PR) program on depressions scores in persons with COPD and if there is a difference between males and females in depression scores prior to and following participation in a pulmonary rehabilitation program. The literature review supported multiple factors on how participating in a pulmonary rehabilitation program can have a positive effect on depression scores. The study utilized a descriptive design with a retrospective chart review. The quantitative descriptive design identified variables and examined the differences in males and females with COPD using pre- and …

The Effects Of A Brief Mindfulness-Based Meditation Intervention On Chronic Pain, Jolena B. Allred

Nursing Theses and Capstone Projects

As the number of individuals suffering with chronic pain escalates, management is shifting from pain specialists to primary care providers. Nurse practitioners are becoming increasingly responsible for the management of this complex patient population. Analgesics, primarily opioids, have been the standard of chronic pain management with a resulting national crisis related to overuse, improper use, and illegal use of these substances. Mindfulness-based meditation has gained increasing interest and acceptance by both the individuals suffering with chronic pain and the providers managing those who suffer, however, limited investigation is available related to brief interventions provided at point-of-care. This Capstone Project evaluated …