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2016

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Articles 961 - 967 of 967

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Geriatric Medicine And Heat Shock Gene Therapy In Global Populations, Ian J. Martins Jan 2016

Geriatric Medicine And Heat Shock Gene Therapy In Global Populations, Ian J. Martins

Research outputs 2014 to 2021

No abstract provided.

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Magnesium Therapy Prevents Senescence With The Reversal Of Diabetes And Alzheimer’S Disease, Ian James Martins Jan 2016

Magnesium Therapy Prevents Senescence With The Reversal Of Diabetes And Alzheimer’S Disease, Ian James Martins

Research outputs 2014 to 2021

In the current global epidemic for Non Alcoholic Fatty Liver Disease (NAFLD), diabetes and neurodegenerative diseases such as Alzheimer’s disease there has been a major interest in magnesium therapy to delay the severity of NAFLD, Type 3 diabetes and neurodegeneration in the developing and developed world. The objective of magnesium therapy is to activate the anti-aging gene Sirtuin 1 (Sirt1) to prevent cardiovascular disease, NAFLD and diabetes. Reduced consumption of nutrients such as fatty acids, glucose, cholesterol and increased magnesium consumption is closely linked to reduced bacterial lipopolysaccharides (LPS) and activation of Sirt1 relevant to active nuclear and mitochondria interactions …

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Classifying Identity: Organizing An Lgbt Library, Kristine Nowak, Amy Jo Mitchell Jan 2016

Classifying Identity: Organizing An Lgbt Library, Kristine Nowak, Amy Jo Mitchell

Library Philosophy and Practice (e-journal)

Although we tend to see classification as a socially and morally neutral activity, classification systems often incorporate societal prejudices and marginalize disadvantaged populations. These systematic prejudices are not only problematic because they are oppressive, but they also impair successful information access. In this paper, we will discuss our work as librarians at the Gay and Lesbian Services Organization (GLSO), a pride center in Lexington, Kentucky. We will discuss the problems that resulted from initially using Library of Congress classification to classify a library of LGBT materials, as well as our decision to create a unique classification system for that collection. …

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Il-15 Mediates Mitochondrial Activity Through A Ppar𝛿-Dependent-Ppar𝛼-Independent Mechanism In Skeletal Muscle Cells, Shantaé M. Thornton, James E. Krolopp, Marcia J. Abbott Jan 2016

Il-15 Mediates Mitochondrial Activity Through A Ppar𝛿-Dependent-Ppar𝛼-Independent Mechanism In Skeletal Muscle Cells, Shantaé M. Thornton, James E. Krolopp, Marcia J. Abbott

Health Sciences and Kinesiology Faculty Articles

Molecular mediators of metabolic processes, to increase energy expenditure, have become a focus for therapies of obesity. The discovery of cytokines secreted from the skeletal muscle (SKM), termed “myokines,” has garnered attention due to their positive effects on metabolic processes. Interleukin-15 (IL-15) is a myokine that has numerous positive metabolic effects and is linked to the PPAR family of mitochondrial regulators. Here, we aimed to determine the importance of PPAR𝛼 and/or PPAR𝛿 as targets of IL-15 signaling. C2C12 SKM cells were differentiated for 6 days and treated every other day with IL-15 (100 ng/mL), a PPAR𝛼 inhibitor (GW-6471), a PPAR𝛿 …

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The Role Of Nadph Oxidase 2 (Nox2) In High-Fat Diet-Induced Adiposopathy And Brain Dysfunction In A Mouse Model, Jennifer Kathleen Pepping Jan 2016

The Role Of Nadph Oxidase 2 (Nox2) In High-Fat Diet-Induced Adiposopathy And Brain Dysfunction In A Mouse Model, Jennifer Kathleen Pepping

LSU Master's Theses

Obesity can have numerous detrimental consequences, namely metabolic syndrome, type 2 diabetes, cardiovascular disease, cancer, and Alzheimer’s disease. The pathogenesis and physiologic consequences of obesity are unknown, but they are often associated with increased inflammation and oxidative stress in both the body and in the brain. One factor that has been implicated in causing inflammation associated with a high fat diet is the enzyme NADPH oxidase, or NOX, specifically the subunit NOX2. Two studies were performed in order to assess the effects of a high fat diet in combination with a universal NOX2 deficiency and a NOX2 deficiency targeted to …

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Individuals With Dementia In Respite Care: Longitudinal Changes In Anxiety, Social Engagement, And Problem Behaviors, Rachael Elizabeth Mills Jan 2016

Individuals With Dementia In Respite Care: Longitudinal Changes In Anxiety, Social Engagement, And Problem Behaviors, Rachael Elizabeth Mills

LSU Master's Theses

Individuals with Alzheimer’s disease (AD) and dementia commonly referred to as persons with dementia (PWD), often experience behavioral and psychological symptoms as a result of the disease process. With no cure for AD and no way to prevent the onset of this disease, studies are analyzing methods to manage the symptoms of this disease. Previous literature on the effect of social adult day models is limited, especially pertaining to particular symptoms linked to this disease. This study explored three presenting symptoms associated with AD: anxiety, problem behaviors, and social engagement. Using a secondary data analysis, a sample of 30 participants …

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Successful Aging In Oldest-Old Adults: Role Of Physical And Social Factors, Katie Elizabeth Stanko Jan 2016

Successful Aging In Oldest-Old Adults: Role Of Physical And Social Factors, Katie Elizabeth Stanko

LSU Master's Theses

Successful aging, increasing in chronological age while maintaining health, is related to a multitude of factors including social and physical behaviors. Older adults may report that they are aging successfully while biomedical outcomes suggest otherwise. In the present study, sociodemographic characteristics, social engagement, physical activity in relation to frailty and health-related quality of life (HR QoL) were examined using a lifespan sample of adults (N = 732) from the Louisiana Healthy Aging Study (LHAS). Four age groups were compared: younger (21-44 years), middle-aged (45-64 years), older (65-84 years), and oldest-old adults (85 to 101 years). A main effect of age …

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