Digital Commons Network^™

Molecular Dynamics Simulations Of Stimuli-Responsive Polymers, Arjun Sharma

LSU New Orleans Theses and Dissertations

Polymers that undergo dramatic changes in structural conformations in response to numerous stimuli such as temperature, pH, electric and magnetic fields, light inten- sity, biological molecules, and solvent polarity, are known as stimuli-responsive or ”smart” polymers. There is a broad range of very promising applications of these materials in catalysis, environmental remediation, sensors or actuator systems, and as delivery systems of therapeutic agents. Researchers have been trying to mimic smart polymers based on properties of polymers found in nature such as proteins, carbohydrates and nucleic acids. Novel bio-compatible polymers with a variety of chemical functional groups, diverse topologies, and cross-linking …

Territoriality And Spatial Structure In The Green Anole, Anolis Carolinensis, William D. Weber Jr.

LSU New Orleans Theses and Dissertations

Anolis carolinensis has been a model organism for ecology and evolutionary biology since the seventies, yet there are still understudied aspects of their ecology. A five-year study has provided microsatellite genotypes to be used in building a pedigree and assess relatedness, enabling us to evaluate the spatial distribution of an urban population of A. carolinensis. Results indicate no correlation between a male’s size and the distance others keep from it; however, males belonging in the heavyweight morph are dictating the spatial distribution in this population. In addition, juvenile dispersal of male offspring and partial philopatry of female offspring are …

Parenting Style And Adolescent Gender As Moderators Of The Association Between Parental Restrictions And Adolescents' Risky Driving, Megan M. Zeringue

LSU New Orleans Theses and Dissertations

Motor vehicle crashes are the leading cause of teenage deaths in the United States, highlighting the need for ways to reduce teenage driver crash rates. Adolescents (n = 176, M age = 16.4 years, 53% female) and their parents (n = 204, 71% mothers) self-reported on parenting style, driving restrictions, and risky driving. Results showed that more parental restrictions were associated with less adolescent risky driving. Three-way interactions were found such that more restrictions were associated with less concurrent risky driving in boys only under conditions of high parental warmth, structure, or autonomy support. Parenting style generally did …

An Investigation Into The Origin, Composition, And Commercial Significance Of A Sedimentary Subsalt Formation: Keathley Canyon, Gulf Of Mexico, David Aaron Brassieur

LSU New Orleans Theses and Dissertations

Sub-salt oil and gas formations in deep-water northern Gulf of Mexico are high priority targets. Advances in seismic processing allow for high-resolution, below-salt imaging. Understanding the modes of salt emplacement provide insight into sub-salt traps and potential drilling hazards.

A sub-salt sedimentary unit lies in the Keathley Canyon protraction. Autosutures created the transport-parallel lineaments of the upper surface of the unit. In addition, highly variable sediment aggradation rates created ramps, flats, and basal cutoffs along the base of the allochthon as salt and sediment competed for space. Seismic models identify modes of salt emplacement, salt/sediment interactions, and mechanisms responsible for …

Chimerscope: A Novel Alignment-Free Algorithm For Fusion Gene Prediction Using Paired-End Short Reads, You Li

Theses & Dissertations

Fusion genes are those that result from the fusion of two or more genes, and they are typically generated due to the perturbations in the genome structure in cancer cells. In turn, fusion genes can contribute to tumor formation and progression by promoting the expression of an oncogene, deregulation of a tumor-suppressor, or producing much more active abnormal proteins. More importantly, oncogenic fusion genes are specifically expressed in the tumor cells, which provide enormous diagnostic and therapeutic advantages for cancer treatment. With the development of next-generation sequencing (NGS) technology, RNA-Seq becomes increasingly popular for transcriptomic study because of its high …

Dna Polymerase Zeta-Dependent Mutagenesis: Molecular Specificity, Extent Of Error-Prone Synthesis, And The Role Of Dntp Pools, Olga V. Kochenova

Theses & Dissertations

Despite multiple DNA repair pathways, DNA lesions can escape repair and compromise normal chromosomal replication, leading to genome instability. Cells utilize specialized low-fidelity Translesion Synthesis (TLS) DNA polymerases to bypass lesions and rescue arrested replication forks. TLS is a highly conserved two-step process that involves insertion of a nucleotide opposite a lesion and extension of the resulting aberrant primer terminus. The first step can be performed by both replicative and TLS DNA polymerases and, because of non-instructive DNA lesions, often results in a nucleotide misincorporation. The second step is almost exclusively catalyzed by DNA polymerase ζ …

Regulation Of Alteration/Deficiency In Activation 3 (Ada3) By Acetylation And Its Role In Cell Cycle Regulation And Oncogenesis, Shashank Srivastava

Theses & Dissertations

The ADA3 (Alteration/Deficiency in Activation 3) protein is a transcriptional adaptor protein that was initially discovered as a component of several HAT (Histone Acetyltransferase) complexes, the enzyme complex responsible for histone acetylation, which is a prerequisite for transcription. Earlier the studies from Dr. Band’s laboratory and that of others’ have deciphered a crucial role of ADA3 in cell cycle regulation (both through G₁/S and G₂/M phase transitions) and in maintaining the genomic stability.

While our laboratory investigated the mechanism behind the role of ADA3 in G₁/S transition, the same remained unknown for G_{2 …}

Role Of Cbl-Family Ubiquitin Ligases As Critical Negative Regulators Of T Cell Activation And Functions, Benjamin Goetz

Theses & Dissertations

Adaptive T cell immunity is essential for defense against foreign antigens and immune surveillance against cancer. Tight regulation of T cell activation is required to avoid autoimmunity to self-antigens or protracted inflammation after foreign antigens are cleared. Incomplete or inappropriate stimulation leads to an active shutdown of T cell activation called anergy. The Casitas B-lineage Lymphoma (CBL)-family of ubiquitin ligases (E3s) are essential negative regulators of T cell activation that impinge on thymic selection as well as anergy induction programs. Single gene studies show that CBL is critical during T cell development while CBL-B plays an essential role in peripheral …

Facilitating The Emergence Of Convergent Intraverbals In Children With Autism, Andresa Desouza

Theses & Dissertations

With intraverbal relations, one speaker’s verbal behavior controls another speaker’s verbal behavior. Convergent intraverbals represent a specific type of intraverbal in which multiple components of one speaker’s verbal behavior control a specific verbal response from another speaker (e.g., Speaker 1: what wooly, horned animal lives in the high country? Speaker 2: a mountain goat). Learning intraverbal relations under the control of multiple variables is critical to language, social, and academic development. Sundberg and Sundberg (2011) identified prerequisites that may engender the emergence of novel, convergent intraverbals. We used a multiple-probe design with both nonconcurrent (across participants) and concurrent (across sets …

Adoption Of Medication Management Technologies By U.S. Acute Care Hospitals After The Hitech Act, Aastha Chandak

Theses & Dissertations

Medication errors and adverse drug events (ADEs) are a significant public health concern in the United States as they pose a threat to patient safety. The medication management process is a complicated process in U.S. acute care hospitals, consisting of a series of steps such as ordering, transcribing, dispensing and administration and each step is prone to medication errors.The use of technology is considered to be an important intervention in improving the medication management process and thereby reducing medication errors and ADEs and further improve patient safety. The Health Information Technology for Economic and Clinical Health (HITECH) Act, implemented in …

911 Calls In Homicide Cases: What Does The Verbal Behavior Of The Caller Reveal?, Jon D. Cromer

Masters Theses, 2010-2019

Each year, numerous 911 calls reporting a death or a serious injury that leads to death are received by emergency communications centers; many of these turn out to be related to a homicide. Interestingly, a small percentage of these calls are made by the perpetrator. These calls constitute the first available evidence in most homicide cases. They are recorded at times of great stress and are the first versions of what the callers purport to know. The ability to develop hypotheses about a caller’s truthfulness enhances the police response by objectively informing the process of formulating early investigative strategies. For …

Primer On Perspectives And Practices Of Trauma, Trevor P. Haase

Educational Specialist, 2009-2019

A large majority of the general population has endured at least one traumatic event in their lifetime and many will seek counseling services to process and resolve the impact from the traumatic experience. Counselors and mental health providers will likely encounter trauma survivors in a high frequency in the majority of therapeutic settings. Practicum and internship level counselors are often not prepared for navigating the complexities that arise working with trauma survivors. This paper outlines the various perspectives and practices of the works of Dr. Bessel van der Kolk, Narrative Therapy, and Trauma Focused-Cognitive Behavioral Therapy. These orientations were designed …

Occurrence, Antibiotic Resistance, And Survival Of Fecal Enterococci In Turkey Litter, Steven Glynn Mcbride Ii

Masters Theses, 2010-2019

The United States Environmental Protection Agency’s National Water Quality Inventory and the Commonwealth of Virginia’s 305(b)/303(d) Water Quality Assessment Integrated Report show fecal bacteria to be the most common cause of impairment for both streams and estuaries. Human and animal sources have both been identified as significant contributors of pathogenic bacteria to surface waters. In this study, turkey litter from a farm in Shenandoah County, VA was surveyed for total culturable bacteria and total culturable enterococci before and after a transition to organic rearing practices. The enterococci were identified to species phenotypically using the Biolog Microbial Identification System and resistance …

The Inter- And Intra-Rater Reliability Of Athletic Trainers At Identifying Acl Injury Risk Factors Using The Cutting Screening Tool, Kelly Buckholz Smallbeck

Master's Theses

Background: ACL injuries are a frequently talked about injury in sports and have a multitude of negative side effects. A majority of injuries occur during single-leg cutting motions. Clinical screening tools are an effective way to identify those demonstrating more ACL injury risk factors. Recent research has created a variety of clinical screening tools to identify ACL injury risk factors, however none screen athletes during a single-leg cutting motion.

Hypothesis: A clinical screening tool using a single-leg cutting motion (the Cutting Screening Tool, or CST) will reliably identify ACL injury risk factors when used by athletic trainers.

Methods: Six currently …

Utilizing Pre-Education Assessment And A Targeted Education Module To Enhance Nurse Knowledge Of Standard And Transmissible Precautions, Deborah A. Ard

Master's Projects and Capstones

Abstract

The aim of this project was to protect patient safety and prevent healthcare acquired infections by improving nurses’ knowledge of infection prevention practices. A second practical benefit was creating a pilot for an RN education program.

I propose that the reason compliance with hand hygiene is low at any facility can be explained by Rosenstock’s Health Belief Model. Nurses may not believe that 1) There is a high chance of spreading or themselves contracting infectious illness, 2) That the illnesses they are exposed to would be just as serious in them as they are seeing in patients, 3) They …

Improving Cal Nagpra: Honoring Native American Rights, Kim Turner

Master's Projects and Capstones

The California Native American Graves Protection and Repatriation Act (Cal NAGPRA) became state law in 2001. Its purpose was to create a process whereby California tribes could seek to repatriate human remains and objects from their cultural heritage from museums and custodial institutions. Cal NAGPRA includes a number of shortcomings that have impeded the ability of tribes to successfully reclaim objects from their heritage. The ethical implications of museums retaining cultural objects and human remains, often confiscated from Native peoples or their tribal lands, has been a principal social justice topic of USF’s museum studies program. This capstone describes a …

Inside The Juvenile Justice System, Megan Phalon

Master's Projects and Capstones

The United States of America is known for freedom and integrity and being a nation that stands for justice and equality for all. Within the United States there are systems in place to better the people and communities in order to provide safety and order. However, just as any nation, there is a struggle with violent behavior and tendencies among adults and adolescents. Within the last three decades, the United States has created a correctional system that specifically targets adolescents, and that acknowledges the differences between adult and juvenile development and deviant behavior. Within this literature review, academic databases were …

Alternative Protein Sources In The Diet Modulate Microbiota And Functionality In The Distal Intestine Of Atlantic Salmon ( Salmo Salar ), Karina Gajardo, Alexander Jaramillo-Torres, Trond M. Kortner, Daniel L. Merrifield, John Tinsley, Anne Marie Bakke, Åshild Krogdahl

School of Biological and Marine Sciences

No abstract provided.

‘You’Re Nobody Till Somebody Kills You’: How Tupac Shakur Secured His Place In The Hall Of Fame, Joseph Devin Holt

Capstones

The piece is a critical essay about the work and life of Tupac Shakur, pegged to his recent nomination for the Rock N' Roll Hall of Fame, and the two movies about him planned for 2017. My multimedia elements are photos and an audio essay.

http://devinistyping.com/tupac/

Increasing Patient Satisfaction And Decreasing Hospital Readmission Due To Deep Venous Thrombosis By Providing Anticoagulation Education For Orthopedic Patients, Margaret Gniewosz

Master's Projects and Capstones

Abstract

Improving Process on Oral Anticoagulant Education for Orthopedic Patients

The aim of this project is to improve anticoagulation education for orthopedic patients to increase patient satisfaction. The microsystem for this project is a medical-surgical (MS), 50-bed unit in a medium size hospital. Because orthopedic patients are at high risk to develop DVT postoperatively, proper anticoagulants and anticoagulation education is an important aspect of patient care. By implementing a well-designed and easy-to-read patient handout on anticoagulants with instructional script for nurses will empower patients to achieve higher level of anticoagulant knowledge and in result, increase patient satisfaction. A preliminary round …

History In Collaboration: Equalizing The Arts And The Humanities In San Francisco, Nicole C. Meldahl

Master's Projects and Capstones

Historically, there has been a critical imbalance in the way history and preservation organizations are civically supported in comparison with the amount of funding that is available to arts organizations in the United States. To correct this imbalance in San Francisco, I propose the creation of a San Francisco Department of Culture that would place the San Francisco Arts Commission equally alongside a San Francisco History Commission within a department that absorbs responsibilities currently managed by other divisions with in city government, such as the Planning Department and the Office and Economic and Workforce Development. City government necessarily takes time …

Decolonial Interstice In Carnaval Montevideano: Murga As Hegemonic Dissent At The Tablado De Barrio, Paola García

Master of Arts in American Studies Capstones

Murga is a popular carnival genre in Montevideo, Uruguay. Carnival in Montevideo lasts 40 days in the summer months of January through March but is different from carnival celebrations in Argentina and Brazil. Carnival performances are competitive and occur in neighborhood stages (tablados de barrio) and private stages (tablados comerciales). A government body judges performances to determine a winning group from each of the five performance genres: Sociedad de Negros y Lubolos, Revista, Humorista, Parodista, and Murga. Murga is a musical and theatrical performance that utilizes satire to convey dissent towards quotidian occurrences of heteronormativity. Numerous communities outside of Montevideo …

Sorption And Metabolism Of Explosives In Sediment Of Coastal Marine Ecosystems, Thivanka S. Ariyarathna

Doctoral Dissertations

The lack of knowledge on fate and transport of explosive compounds, 2,4,6-trinitrotoluene (TNT) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in marine ecosystems limits the ability to predict toxicological impacts and natural attenuation of these suspected carcinogens in contaminated coastal sites. This study focuses on improving our understanding of the sorption and transformation of TNT and RDX in coastal ecosystems by using stable nitrogen isotopes.

Abiotic and biotic bench-top experiments using sediment slurries evaluated sorption kinetics and anaerobic biotransformation. Marine silt showed higher compound-uptake rates (> ~100) than freshwater silt for both compounds though equilibrium partition constants (Kp’s) were on the same order of …

Intolerance Of Uncertainty, Worry, And Problem-Solving: Implications For Generalized Anxiety Disorder, Melissa Patrick

Electronic Theses & Dissertations

This study was conducted to examine the correlations between Generalized Anxiety Disorder (GAD), worry, intolerance of uncertainty (IU), and problem-solving. The Generalized Anxiety Disorder Questionnaire for DSM-IV (GADQ-IV), the Penn State Worry Questionnaire (PSWQ), the Intolerance of Uncertainty Scale (IUS), and the Problem-Solving Inventory (PSI) were used to assess the relationship between GAD, worry, IU, and problem-solving. While the GADQ-IV, PSWQ, and the IUS assessed generalized anxiety, worry, and intolerance of uncertainty as single constructs, the PSI assessed problem-solving in terms of problem-solving confidence, approach avoidance style, and personal control. Data of 86 students in general psychology classes at Pittsburg …

Facial Microbiota And Antibiotic Resistance: A Comparative Study Observing The Presence Of Resistance Genes And Diminished Susceptibility, Kayla R. Stricklan

Electronic Theses & Dissertations

The looming threat of increased antibiotic resistance leading to a post-antibiotic world is progressively becoming a reality. A significant portion of the fight against antibiotic resistance development is slowing down the prescribing of antibiotics for unnecessary conditions while simultaneously encouraging stricter adherence to antibiotic course completion. One of the often-unnecessary conditions is acne vulgaris. Though the disease may be unsightly and discouraging, it does little to affect overall health of the individual with the exception of psychosocial affects. Utilizing facial swabs from 144 participants, samples were tested for the colonization of Propionibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis as …

The Psychological Impacts Of Engaging In Creative Work, Jeanine Kunshek

Electronic Theses & Dissertations

Although the literature investigating creativity is extensive, this research is designed to address deficits in knowledge regarding the first-hand accounts of individuals who engage in creative work and the motivations and gratifications they draw from those experiences. This study employs the use of in vivo analysis to articulate and explore the benefits and disadvantages of individuals who pursue careers in five creative industries identified by Taylor and Littleton (2012). Based on qualitative data gathered from focus groups and interviews, most frequent benefits include social connections, cognitive challenges, boosted esteem, communication, and personal and professional development. Disadvantages include time demands, lack …

Graduate Piano Recital, Liping Xia

Electronic Theses & Dissertations

The Graduate Piano Recital is the main recital of the Master’s degree which is one hour in length. The repertoire for my graduate piano recital includes: Estampes (Pagodes, La soirée dans Grenade and Jardins sous la pluie), by Claude Debussy; Variationen über das Motiv von Bach S.180 by Franz Liszt; and Piano Sonata No. 21 in C major, Op. 53 by Ludwig Van Beethoven. This thesis will discuss the biography and musical style of each composer, the structure and analysis of each piece, and provide performance suggestions for each piece as well.

Does Attentional Slippage Conform To A Simple Gradient?, Katie Rennie

Electronic Theses & Dissertations

The following graduate thesis describes research designed to examine flanker interference at varying spatial distances from a target stimulus. Traditionally, much evidence has accumulated that the distribution of visual attention conforms to a monotonically decreasing gradient in which distractors at the farthest separations produce the least interference (e.g., Erikson & St. James, 1986). Different from this traditional conceptualization, Müller, Mollenhauer, Rösler, and Kleinschmidt (2005) describe what they termed a Mexican hat distribution of visual attention showing flankers at an intermediate zone produce less interference. The current study is designed to investigate whether flanker interference declines monotonically with distance or follows …

Burnout In Radiation Therapy: Examining The Six Leading Influences, Gina C. Passmore

All Theses And Dissertations

Recent studies are highlighting the dangers of burnout amongst healthcare workers, including radiation therapists. Since burnout is associated with an increase in medical errors (Sanchez-Reilly, 2013), it affects both the well-being of the patient and patient satisfaction scores, which are important to a hospital’s reputation. Burnout has a positive correlation with job dissatisfaction and increased employee turnover, making it both a financial and quality issue. Organizations acknowledge that burnout leads to unhappy employees, and unhappy employees are less likely to be engaged in their work, thereby not producing the best “products” (Sehlen, 2009). By examining which components seem to be …

Increasing Chlorhexidine (Chg) Daily Bathing Compliance, Jonathan Lee

Master's Projects and Capstones

Chlorhexidine gluconate (CHG) daily bathing in hospitalized patients in the intensive care setting is one of many interventions implemented by institutions to reduce and prevent central line associated bloodstream infections (CLABSIs) and catheter associated urinary tract infections (CAUTIs). These hospital-acquired infections (HAIs) plague and complicate treatments for critically ill patients in the acute care setting. CLABSIs and CAUTIs increase patient morbidity and mortality as well as place a financial burden with increased costs and hospital lengths of stay. The decrease of CHG compliance in our ICU unit can be associated with an elevated CLABSI rates. The focus of this CNL …