Digital Commons Network^™

Investigation Of Radiation Injury In The Esophagus From Definitive Chemoradiation Therapy Using Novel Imaging Biomarkers, Joshua S. Niedzielski

Dissertations and Theses (Open Access)

Radiation injury in the esophagus occurs with high frequency from the treatment of non-small cell lung cancer (NSCLC). Radiation esophagitis is an acute normal tissue toxicity that negatively affects treatment efficacy by limiting dose and potentially interrupting radiation therapy. Clinical quantification of this toxicity is typically achieved by utilizing physician grading scales, assigning complication severity on an ordinal scale of symptom presentation and/or physician chosen interventions. These criteria are subjective in nature, both from the physician assigning the grade and the patient reporting the symptom. Furthermore, radiation therapy planning guidelines for the esophagus are derived from toxicity prediction models utilizing …

Cellular And Genetic Bases Of Cold Nociception And Nociceptive Sensitization In Drosophila Larvae, Heather N. Turner

Dissertations and Theses (Open Access)

Organisms from flies to mammals utilize thermoreceptors to detect and respond to noxious thermal stimuli. Although much is understood about noxious heat avoidance, our understanding of the basic biology of noxious cold perception is gravely minimal. Numerous clinical conditions disrupt the sensory machinery, such as in patients suffering from tissue damage (from wound or sunburn), or injury to the peripheral nerves, as in patients with diabetes or undergoing chemotherapy. Our goal is to determine the genetic basis for noxious cold perception and injury-induced nociceptive sensitization using the genetically tractable Drosophila model. Using a novel "cold probe" tool and assay we …

Novel Simulation To Avoid Bias In Measurement Of Hyperpolarized Pyruvate: Demonstrated In Phantom And In Vivo, Christopher M. Walker

Dissertations and Theses (Open Access)

Dynamic nuclear polarization creates a transient hyperpolarized nuclear state that can dramatically increase the signal detected by magnetic resonance imaging. This signal increase allows real-time spectroscopic imaging of specific metabolites in vivo by magnetic resonance. Real-time imaging of both the spatial and chemical fate of hyperpolarized metabolites is showing great promise to meaningfully benefit clinical care of cancer patients. Imaging of hyperpolarized agents will have a larger clinical impact if it can function as a quantitative modality upon which clinical decisions can be made. However, quantitative measurement of hyperpolarized agents is currently difficult due to the restrictions imposed by the …

Some Spectral Properties Of A Quantum Field Theoretic Hamiltonian, Devin Burnell Mcghie

Theses and Dissertations

We derive the ground-state eigenvalues and eigenvectors for a simplified version of the 1-D QED single electron-photon model that Glasgow et al recently developed [2]. This model still allows for meaningful interaction between electrons and photons while keeping only the minimum needed to do so. We investigate the interesting spectral properties of this model. We determine that the eigenvectors are orthogonal as one would expect and normalize them.

Evidence For The Validity Of The Student Risk Screening Scale In Middle School: A Multilevel Confirmatory Factor Analysis, Matthew Porter Wilcox

Theses and Dissertations

The Student Risk Screening Scale—Internalizing/Externalizing (SRSS-IE) was developed to screen elementary-aged students for Emotional and Behavioral Disorders (EBD). Its use has been extended to middle schools with little evidence that it measures the same constructs as in elementary schools. Scores of a middle school population from the SRSS-IE are analyzed with Multilevel Confirmatory Factor Analysis (MCFA) to examine its factor structure, factorial invariance between females and males, and its reliability. Several MCFA models are specified, and compared, with two retained for further analysis. The first model is a single-level model with chi-square and standard errors adjusted for the clustered nature …

A Secure, Reliable And Performance-Enhancing Storage Architecture Integrating Local And Cloud-Based Storage, Christopher Glenn Hansen

Theses and Dissertations

The constant evolution of new varieties of computing systems - cloud computing, mobile devices, and Internet of Things, to name a few - have necessitated a growing need for highly reliable, available, secure, and high-performing storage systems. While CPU performance has typically scaled with Moore's Law, data storage is much less consistent in how quickly performance increases over time. One method of improving storage performance is through the use of special storage architectures. Such architectures often include redundant arrays of independent disks (RAID). RAID provides a meaningful way to increase storage performance on a variety of levels, some higher-performing than …

The Invisible Revolution In Plea Bargaining: Managerial Judging And Judicial Participation In Negotiations, Nancy J. King, Ronald F. Wright

Vanderbilt Law School Faculty Publications

This Article, the most comprehensive study ofjudicial participation in plea negotiations since the 1970s, reveals a stunning array of new procedures that involve judges routinely in the settlement of criminal cases. Interviewing nearly one hundred judges and attorneys in ten states, we found that what once were informal, disfavored interactions have quietly, without notice, transformed into highly structured best practices for docket management. We learned of grant-funded problem-solving sessions complete with risk assessments and real-time information on treatment options; multicase conferences where other lawyers chime in; settlement courts located at the jail; settlement dockets with retired judges; full-blown felony mediation …

James D. Cox: The Shareholders Best Advocate, Randall S. Thomas, Harwell Wells

Vanderbilt Law School Faculty Publications

This Article explores the historical development of the academic analysis of corporate law over the past forty years through the scholarship of one of its most influential commentators, Professor James D. Cox of the Duke University School of Law. It traces the ways in which corporate law scholarship changed from the 1970s to the present, including the rise of economic theory and empirical work in the study of corporate law. It shows how Professor Cox's early scholarship shaped and challenged economic orthodoxy, while his later work used empirical analysis to help corporate law become a more dynamic and richer field. …

Judging Foreign States, Zachary D. Clopton

Cornell Law Faculty Publications

Famed foreign relations law principles, including the act of state doctrine, the public law taboo, and Zschernig’s foreign affairs preemption, rely on the notion that U.S. courts should not sit in judgment on foreign states. Judges in these cases, as well as scholars writing in the area, frequently suggest that U.S. courts should sit out of important disputes due to considerations of sovereign equality and international comity. Yet, in less attention-grabbing cases, U.S. courts routinely sit in judgment on foreign judgments, laws, legal systems, and interests, sometimes concluding that they do meet U.S. standards. The first goal of this project, …

Vanadium Diselenide: On The Verge Of Charge Density Wave, Menghan Zhou

All Dissertations

Charge density wave (CDW) is a many-body state of matter in which both lattice and electron density are modulated by a new periodicity. CDW features discrete translational symmetry breaking, and mostly occurs in low-dimensional materials. Although CDW behaviors have been found in many materials, the underlying mechanism and the driving forces of CDW transition are still unclear. In particular, the origin of CDW in two-dimensional materials, especially in layered transition metal dicalchogenides (TMDCs), may be distinct from that in one-dimensional materials.

In this dissertation, the CDW transition in VSe2, a layered TMDC material, is explored. Density functional theory (DFT) calculations …

Investigation Of Lipid Profile Patterns Along Latitude In An Eastern Australian Cline And After Stress Selection In The Laboratory, And Experiments On Stress Tolerance With Rnai Knockdown Of Lipid Biosynthesis Genes, Li Ko

School of Biological Sciences: Dissertations, Theses, and Student Research

Homeoviscous adaptation in membranes and changes in energy storage lipids such as triacylglycerols (TAGs) are the two main themes of adaptation to environmental conditions. Basal patterns of lipid compositional profile of Drosophila melanogaster along a latitudinal gradient in the eastern coast of Australia indicate variations of lipidome associated with climatic patterns. Lipidome data were collected for eight locations along the eastern Australian cline for both sexes in D. melanogaster and D. simulans. To further investigate the relationship between lipidome patterns and environmental factors, we utilized laboratory selection studies using stress conditions including high temperature tolerance, desiccation survival, and chill-coma …

Determining The Optimal Public Debt Threshold For Nigeria, Babatunde S. Omotosho, Sani Bawa, Sani I. Doguwa

CBN Journal of Applied Statistics (JAS)

This paper investigates the existence of threshold effects in the relationship between public debt and economic growth in Nigeria using quarterly data. Generally, we found empirical support for an inverted U-shape relationship between public debt types and economic growth. For total public debt as percentage of GDP, model results identified a threshold level of 73.70 per cent, while the estimated inflexion points for external and domestic debts were 49.4 and 30.9 per cent, respectively. The implication of this finding is that debt accumulation in excess of the estimated threshold levels could hurt economic growth. A retrospective examination of the country’s …

Volatility In The Nigerian Stock Market: Empirical Application Of Beta-T-Garch Variants, Olaoluwa S. Yaya, Abiodun S. Bada, Victor N. Atoi

CBN Journal of Applied Statistics (JAS)

The Generalized Autoregressive Score (GAS), Exponential GAS (EGAS) and Asymmetric Exponential GAS (AEGAS) are new classes of volatility models that simultaneously account for jumps and asymmetry. Using these models, we estimate the dynamic pattern of the Nigeria All Share Index (ASI) from January 3, 2006 to July 22, 2014. Parameter estimates of the models were obtained using the Quasi Maximum Likelihood (QML) approach, and in-sample conditional volatility forecasts from each of the models were evaluated using the minimum loss function approach. Among the classical volatility models, the initial results detected IGARCH-t as the best model for predicting volatility in the …

The Causes Of Persistent Inflation In Nigeria, Victor O. Asekunowo

CBN Journal of Applied Statistics (JAS)

This study sought to identify the traditional and institutional inflation variables responsible for inflation phenomenon and the magnitude of the contribution of the identified variables to the rise in general price level. Secondary data on key macroeconomic variables in the economy from 1974 to 2013 were used. The data collected were analysed using the Autoregressive Distributed Lag (ARDL) bounds test. The results showed that there existed a longrun co-movement among the variables. Also, the ordinary least squares estimate showed that Real Effective Exchange Rate, Lagged Consumer Price Index, Real Broad Money and Real Profits were statistically significant in influencing Consumer …

Dynamic Effects Of Fiscal Policy On Output And Unemployment In Nigeria: An Econometric Investigation, Attahir B. Abubakar

CBN Journal of Applied Statistics (JAS)

This study investigates the effect of fiscal policy shocks on output and unemployment in Nigeria under the Keynesian framework by employing the Structural Vector Autoregression (SVAR) methodology to analyse annual series on the relevant variables for the period 1981-2015. Augmented Dickey Fuller (ADF) test for unit root result shows all variables to be integrated of order one and Johansen Cointegration test confirms the presence of long run association among the variables. Findings of the SVAR model shows shock in public expenditure as having a positive long- lasting effect on output. Revenue shock was found to exert a positive effect (lower …

On Building Inference For The Statistical Neural Network With Application To Naira-Dollar Exchange Rate Efficiency: A Bootstrap Approach, Christopher Godwin Udomboso Dr, Francisco U. Saliu

CBN Journal of Applied Statistics (JAS)

In this study, we developed an inference procedure for the neural network using the bootstrap approach, and applied it to the market efficiency of the Nigerian exchange rate. Data used are exchange rate values from 2001 to 2015. We conducted a test on the market efficiency hypothesis, including test for relevance of individual and joint network inputs using method of partial derivative. The network architecture used is the multilayer perceptron. A valid statistical inference based on the estimated Statistical Neural Network was conducted using a well-known statistical resampling technique. Test of hypothesis that input or groups of inputs are relevant …

Modelling Volatility Of The Exchange Rate Of The Naira To Major Currencies, Reuben O. David, Hussaini G. Dikko, Shehu U. Gulumbe

CBN Journal of Applied Statistics (JAS)

The exchange rate between the Naira and other currencies has continued to witness variability with depreciation. This variability makes it difficult to predict returns. Against this background, this paper examines the naira exchange rate vis-a-vis four other currencies. The impact of exogenous variables in modelling volatility is considered using both the GARCH (1,1) and its asymmetric variants. Three of the four returns series showed heteroscedasticity. The results of the fitted models indicate that the majority of the parameters are significant and that volatility is quite persistent. Furthermore, the results of the asymmetric model indicate different impacts for both negative and …

Technology Integration And Student Learning Motivation, Blake A. Wieking

Master's Theses & Capstone Projects

The purpose of this action research project was to determine if there is a correlation between the use of technology in the seventh grade social studies classroom and the motivation for learning. A combination of technology enriched lessons and traditional textbook and pencil lessons were used over a period of nearly two months. Data was collected through quantitative surveys and qualitative observations and responses from students. Analysis of the data collected suggests that student motivation and joy of learning increases as technology is used in the classroom. Traditional methods of instruction were not recorded as memorable or motivational for most …

Expectation-Centered Analytics For Instructors And Students, Suzanne L. Dazo

Student Work

Learning analytics is the measurement, collection, analysis, and reporting of data about learners and their contexts. An outcome and primary goal of learning analytics should be to inform instructors, who are primary stakeholders, so that they can make effective decisions in their courses. To support instructor inquiry, I apply theory on reflective practice to learning analytic development. Articulating an instructor's pedagogical expectations is one way to begin facilitating a reflective practice. Expectations based on instructor goals serve as a natural next step and the springboard from which data can be collected. I hypothesize that a learning analytic that encodes and …

Building Background To Improve Understanding Among English Language Learners, Sara Burmakow

Master's Theses & Capstone Projects

Over the past several years, there has been an increase in the number of English Language Learners (ELL) within the regular classroom setting. Often times, these students know little to no English before walking into the classroom and are expected to learn the same as other students in the classroom. As students learn, they connect new information to previous information naturally. When students lack this background knowledge they have a difficult time making those connections. One way to prevent this from happening is helping build background with the students in the regular classroom setting. Throughout the study, ELLs were worked …

Selection Of Efficient Taq Dna Polymerase To Optimize T-Dna Genotyping Method For Rapid Detection Of Mutant Arabidopsis Thaliana Plants, Inna B. Chastukhina, Liliia R. Nigmatullina, Lia R. Valeeva, Eugene V. Shakirov

Biological Sciences Faculty Research

Plants harbor homologues of various animal genes involved in phosphorus metabolism, telomere biology and other cellular processes. Compared to experiments with many other multicellular organisms, research in the model plant Arabidopsis thaliana takes advantage of short generation time and an ever increasing arsenal of genetic and transgenic tools, including large collections of T-DNA knockout and activation lines. The availability of thousands of publicly available transgenic Arabidopsis lines provides a unique opportunity to address a number of important biological questions. However, identification of individual T-DNA mutant plants from a pool of seeds provided by a biological stock distribution center remains a …

Cross Cultural Regularities In The Cognitive Architecture Of Pride, Daniel Sznycer, Laith Al-Shawaf, Yoella Bereby-Meyer, Oliver Scott Curry, Delphine De Smet, Elsa Ermer, Sangin Kim, Sunhwa Kim, Norman P. Li, Maria Florencia Lopez Seal, Jennifer Mcclung, Jiaqing O, Yohsuke Ohtsubo, Tadeg Quillien, Max Schaub, Aaron Sell, Florian Van Leeuwen, Leda Cosmide, John Tooby

Research Collection School of Social Sciences

Pride occurs in every known culture, appears early in development, is reliably triggered by achievements and formidability, and causes a characteristic display that is recognized everywhere. Here, we evaluatethe theory that pride evolved to guide decisions relevant to pursuing actions that enhance valuation and respect for a person in the minds of others. By hypothesis, pride is a neurocomputational program tailored by selection to orchestrate cognition and behavior in the service of: (i) motivating the costeffective pursuit of courses of action that would increase others’ valuations and respect of the individual, (ii) motivating the advertisement of acts or characteristics whose …

The Trauma Of The Routine: Lessons On Cultural Trauma From The Emmett Till Verdict, Angela Onwuachi-Willig

Faculty Scholarship

Cultural traumas are socially mediated processes that occur when groups endure horrific events that forever change their consciousness and identity. According to cultural sociologists, these traumas arise out of shocks to the routine or the taken for granted. Understanding such traumas is critical for developing solutions that can address group suffering. Using the African American community’s response to the not guilty verdict in the Emmett Till murder trial as a case study, this article extends cultural trauma theory by explicating how cultural traumas can arise not only when routines are disrupted but also when they are maintained and reaffirmed in …

North Dakota Monthly Climate Summary: December 2016

North Dakota Monthly Climate Summary

No abstract provided.

Studies With Dynamic Nuclear Imaging Image Reconstruction Algorithm, Haoran Chang

Theses and Dissertations

Non-negative matrix factorization (NMF) is a useful method for those non-negative multivariate data. In nuclear imaging, NMF, which is also called factor analysis, is used to analyze the 4D image of positron emission tomography and single positron emission computed tomography. Normally, we use factor analysis of dynamic structure (FADS) for the dynamic reconstruction [1]. However, this reconstruction algorithm is extremely dependent on the initial data, which means the result may be unstable when the initial data is not good enough. There are several ways for the initializing, such as splined initialized (SIFADS) [2] and clustering initialized (CIFA) [3][4]. In this …

Effects Of Intelligent Computer-Generated Interactive Mathematics Programs On Students’ Achievement And Affective Domain, Holly Marie Wendel

Theses and Dissertations

The purpose of this study was to determine the relationship each of the mathematics web-based programs, MyMathLab and Assessments and Learning in Knowledge Spaces (ALEKS), has with students’ mathematics achievement. In addition, the study examined the relationship between students’ affective domain and the type of program as well as student achievement. The affective domain measures were students’ anxiety, self-efficacy as well as their attitudes towards mathematics. The study used a quasi-experimental nonrandomized pretest-posttest control group during the spring 2016 semester. The data were collected using several different instruments including: (a) a questionnaire, (b) a test of prerequisite skills, and (c) …

Dec2016, Robert Kelly

Robert Kelly Manuscripts

From December 2016 Robert Kelly archive.

December 2016 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.

Posttraumatic Stress Disorder Associated With Unexpected Death Of A Loved One: Cross-National Findings From The World Mental Health Surveys, Lukoye Atwoli, Dan J. Stein, Andrew King, Maria Petukhova, Sergio Aguilar-Gaxiola, Jordi Alonso, Evelyn J. Bromet, Giovanni De Girolamo, Koen Demyttenaere, Silvia Florescu

Internal Medicine, East Africa

Background: Unexpected death of a loved one (UD) is the most commonly reported traumatic experience in cross‐national surveys. However, much remains to be learned about posttraumatic stress disorder (PTSD) after this experience. The WHO World Mental Health (WMH) survey initiative provides a unique opportunity to address these issues.

Methods: Data from 19 WMH surveys (n = 78,023; 70.1% weighted response rate) were collated. Potential predictors of PTSD (respondent sociodemographics, characteristics of the death, history of prior trauma exposure, history of prior mental disorders) after a representative sample of UDs were examined using logistic regression. Simulation was used to estimate overall …

Ethnicity And Poetry: A Systems Theory Approach To Contemporary African American And Mexican American Poetry, Antonio Paniagua Guzman

Theses and Dissertations

Given the ongoing ethnic transformation of the current society of the United States, contemporary sociologists have extensively studied ethnic relations from diverse theoretical and methodological approaches. Despite the vast sociological research recently developed, the literary-based methodological approach remains partially uncultivated. This study explores motivations and patterns of minority groups’ ethnic performance in contemporary poetry by analyzing inter and intra-group similarities and differences of diverse linguistic and cultural traits. From secondary data analysis, this study examines four hundred poems authored by forty contemporary African American and Mexican American writers experientially connected to the state of Texas. Grounded in systems theory, this …