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Male And Female Differences In Health Benefits Derived From Physical Activity: Implications For Exercise Prescription, Beth P. Hands, Helen Parker, Dawne Larkin, Marja Cantell, Elizabeth Rose

Health Sciences Papers and Journal Articles

Abstract:

Males are consistently reported as more physically active than females regardless of age or measure. Often, this difference results in females identified as under active and at risk of longterm poor health outcomes. In this paper a different perspective drawing on evidence from many sources is offered. Males and females gain different health benefits according to the level, mode and intensity of the physical activity. Some potential ramifications of these gender differences in health benefits are evident in the prevalence of hypokinetic diseases across the life span and the interpretation of measured physical activity levels and intensities. By focusing …

Student Perceptions To Teaching Undergraduate Anatomy In Health Sciences, R Anderton, L Chiu, S Aulfrey

Health Sciences Papers and Journal Articles

Anatomy and physiology teaching has undergone significant changes to keep up with advances in technology and to cater for a wide array of student specific learning approaches. This paper examines perceptions towards a variety of teaching instruments, techniques, and innovations used in the delivery and teaching of anatomy and physiology for health science students, and asks whether active learning through more progressive methods of teaching is beneficial for students across health science disciplines. In total, 138 health science students consisting of 32 biomedical science students, 52 exercise and sports science students, and 54 health and physical education students completed the …

Mechanisms Of Pancreatic Beta Cell Dysfunction In Diabetes, Vaibhav Sidarala

Wayne State University Dissertations

Diabetes is a serious medical condition characterized by decreased insulin secretion from pancreatic β-cells and decreased insulin sensitivity in the peripheral tissues, resulting in elevated levels of blood glucose. According to the International Diabetes Federation, about 387 million cases have been reported worldwide in the year 2013 and it is estimated that about 500 million people would be affected by 2050. Type 2 diabetes, which accounts for about 90% of the total number of cases, is caused by decreased insulin sensitivity in the peripheral tissues and decreased glucose-stimulated insulin secretion from the pancreatic β-cells. The underlying mechanisms involved in β-cell …

Arbitrary Lagrangian-Eulerian Method Investigation On Fuel Tank Strap Simulation Under Proving Ground Condition, Guangtian Song

Wayne State University Dissertations

The Arbitrary Lagrangian-Eulerian (ALE) is a hybrid finite element formulation that can alleviate many of the drawbacks from the traditional Lagrangian-based and Eulerian-based finite element simulations, which is developed through combining modern algorithms for Lagrangian hydrodynamics, meshing technology and remap methods developed for high-resolution Eulerian methods. Lagrangian-based finite element formulations is that the computational system moves with the material and main drawback is that it will face severe problems to deal with strong distortions in the computational domain. Eulerian-based finite element formulations is that the computational system is a prior fixed in space and unable to deal easily with fluids …

An Analysis Of Plasticity In The Rat Respiratory System Following Cervical Spinal Cord Injury And The Application Of Nanotechnology To Induce Or Enhance Recovery Of Diaphragm Function, Janelle Lorien Walker

Wayne State University Dissertations

Second cervical segment spinal cord hemisection (C2Hx) results in ipsilateral hemidiaphragm paralysis. However, the intact latent crossed phrenic pathway can restore function spontaneously over time or immediately following drug administration.

WGA bound fluorochromes were administered to identify nuclei associated with diaphragm function in both the acute and chronic C2Hx models. WGA is unique in that it undergoes receptor mediated endocytosis and is transsynaptically transported across select physiologically active synapses. Comparison of labeling in the acutely injured to the chronically injured rat provided an anatomical map of spinal and supraspinal injury induced synaptic plasticity. The plasticity occurs over time in the …

Saving Innocents: Tracing The Human Monster Hunter’S Hetero-Normative Agenda From The 1970s To Today, Adam Kem Yerima

Wayne State University Dissertations

In supernatural-themed American television programs that focus on hunting or exposing monsters and the monstrous, the human monster hunter’s representation and actions promote a conservative subtext. While horror scholarship prefers to examine the genre’s monsters and women, and regulate the hunter as simply being an expert, an exploration into the historical development of the figure reveals that there is a lot more to this character. The human monster hunter’s televisual depictions from the 1970s to today reveal a complex illustration that reifies the “American dream.” Time and time again, through the loss of an ideal middle-class experience, the human monster …

Expression And Functions Of Il-24 And Socs3 In Pseudomonas Aeruginosa Keratitis In A C57bl/6 Mouse Model, Bing Xu

Wayne State University Dissertations

The aim of this study was to elucidate the expression and functions of interleukin (IL)-24 and suppressor of cytokine signaling 3 (SOCS3), and their regulatory relationship in C57BL/6 mouse corneas in response to Pseudomonas aeruginosa (PA) infection. Among IL-20R cytokines, only IL-24 was induced at both mRNA and protein levels by the infection, and this upregulation was dampened by flagellin pretreatment. Time course studies revealed that IL-24 expression was markedly elevated, followed by a subsidence and second elevation, a pattern shared with SOCS3 but not IL-1β or IL-6. Silencing of IL-24 enhanced S100A8/A9 expression, and suppressed SOCS3, IL-1β, IL-1RN, and …

Novel Regulatory Mechanisms Of Inositol Biosynthesis In Saccharomyces Cerevisiae And Mammalian Cells, And Implications For The Mechanism Underlying Vpa-Induced Glucose 6-Phosphate Depletion, Wenxi Yu

Wayne State University Dissertations

Myo-inositol is the precursor of all inositol containing molecules, including inositol phosphates, phosphoinositides and glycosylphosphatidylinositols, which are signaling molecules involved in many critical cellular functions. Perturbation of inositol metabolism has been linked to neurological disorders. Although several widely-used anticonvulsants and mood-stabilizing drugs have been shown to exert inositol depletion effects, the mechanisms of action of the drugs and the role of inositol in these diseases are not understood. Elucidation of the molecular control of inositol synthesis will shed light on the pathologies of inositol related illnesses.

In Saccharomyces cerevisiae, deletion of the four glycogen synthase kinase-3 genes, MCK1, MRK1, MDS1, …

The Role Of Oxidative Stress In The Establishment Of Resistance To Cisplatin In Epithelial Ovarian Cancer Cells, Jimmy Belotte

Wayne State University Dissertations

Epithelial ovarian cancer is the deadliest of all gynecologic cancers with an estimated 22,280 new cases and 14,240 deaths expected in 2016 in the US alone. This high mortality rate can be partially attributed to a lack of universal screening and the development of resistance to the recommended chemotherapeutics. Typically, the treatment of ovarian cancer requires both cytoreductive surgery (CRS) and platinum/taxane combination chemotherapy. Initially, 50–80% of patients with advanced disease will achieve complete clinical response. Unfortunately, most will relapse within 18 months with chemoresistant disease. Thus, understanding the mechanisms of platinum resistance is critical in order to improve the …

Novelistic Intimacies: Reading And Writing In The Late Age Of Print, Vincent Michael Haddad

Wayne State University Dissertations

In Novelistic Intimacies, I consider the political and aesthetic structure of intimacy in a diverse set of narrative forms produced in the so-called digital age, or the late age of print—from encyclopedic and metafictional novels to graphic storytelling and Afrofuturist fantasy. As an organizing principle, intimacy forces us to consider, at once, how novelists have attempted to restore language and narrative with personal meaning after postmodernism—often termed New Sincerity or post-irony. At the same time, intimacy allows us to see how novelists have experimented on the materiality of the book and the eroticism of language to invent new, impersonal modes …

Cardiolipin Is Required For Optimal Acetyl-Coa Metabolism, Vaishnavi Raja

Wayne State University Dissertations

The phospholipid cardiolipin (CL) is crucial for many cellular functions and signaling pathways, both inside and outside of mitochondria. My thesis focuses on the role of CL in energy metabolism. Many reactions of electron transport and oxidative phosphorylation, the transport of metabolites needed for these processes, and the stabilization of electron transport chain supercomplexes, require CL. Recent studies indicate that CL is required for the synthesis of iron-sulfur (Fe-S) co-factors, which are essential for numerous metabolic pathways. Activation of carnitine-acetylcarnitine translocase, which transports acetyl-CoA into the mitochondria, is CL dependent. The presence of substantial amounts of CL in the peroxisomal …

Loss Of Rap1gap: A Driver In The Progression From Dcis Of The Breast To Idc, Seema Shah

Wayne State University Dissertations

The purpose of this study is to determine the role of Rap1Gap in the progression of DCIS (ductal carcinoma in situ) to IDC (invasive ductal cancer). We employed an in-vitro three-dimensional (3D) overlay model that provides a physiologically relevant microenvironment to study mechanisms of malignant progression. Previous studies from this laboratory aimed to determine specific gene expression changes common to three models of DCIS- MCF10.DCIS, SUM 102 and SUM 225 in comparison to MCF10A cells, a model of non-transformed human mammary epithelium. The expression of 295 genes was found to be significantly altered, with 63 being increased in expression in …

The Ohio State University V. Cafepress, Southern District Of Ohio

Historical and Topical Legal Documents

No abstract provided.

Cornarchy, Hannah Kim, Fleet Library, Special Collections

3rd Student Artists' Book Contest 2017

No abstract provided.

Archimedes And Diabetes, Eric Steinberg, Fleet Library, Special Collections

3rd Student Artists' Book Contest 2017

No abstract provided.

A “Rule-Of-Five” Framework For Models And Modeling To Unify Mathematicians And Biologists And Improve Student Learning, Kam D. Dahlquist

Biology Faculty Works

Despite widespread calls for the incorporation of mathematical modeling into the undergraduate biology curriculum, there is lack of a common understanding around the definition of modeling, which inhibits progress. In this paper, we extend the “Rule-of-Four,” initially used in calculus reform efforts, to a “Rule-of-Five” framework for models and modeling that is inclusive of varying disciplinary definitions of each. This unifying framework allows us to both build on strengths that each discipline and its students bring, but also identify gaps in modeling activities practiced by each discipline. We also discuss benefits to student learning and interdisciplinary collaboration.

V.1 2016-2017, Center For Arts & Language, Students Of Risd, Risd Archives

All Student Newspapers

v.1 is a publishing platform for the ongoing work, ideas, discussions, debates, and aspirations of students at the Rhode Island School of Design. The 2016-2017 issue contains articles on Kara Walker, Women's March, "Look at Art, Get Paid" program, #pizzagate, the Mutual Encounters exhibition, and smartphones.

Seccll Program [2016]

South East Coastal Conference on Languages & Literatures (SECCLL)

N/A

Mormon Studies Review Volume 3, Mormon Studies Review

Mormon Studies Review

No abstract provided.

Contributions On The Spider Families Nesticidae And Pholcidae (Araneae) From Argentina, Victor Manuel Torres, Paolo Luciano Pardo, Andrea Ximena Gonzalez-Reyes, Sandra Monica Rodriguez-Artigas, Jose Corronca

Turkish Journal of Zoology

A new species of Nesticus Thorell, 1869, N. Salta sp. Nov., and a new species of Guaranita Huber, 2000, G. Dobby sp. Nov., are described from the Chaco Serrano ecoregion of Salta Province (Argentina). The female of G. Yaculica Huber, 2000 is described for the first time, and the known distribution of G. Munda (Gertsch, 1982) is enlarged to Jujuy Province, northern Argentina.

Checklist Of The Dolichopodidae (Diptera, Brachycera) Of Turkey, Alper Tonguç, Igor Grichanov, Stefan Naglis

Turkish Journal of Zoology

The first checklist of the Dolichopodidae of Turkey is presented. A total of 187 species and one subspecies belonging to 35 genera are listed. The type locality and the distribution in Turkey for each species are given.

Persistent Threats To Commercial Speech, Jonathan H. Adler

Faculty Publications

The current Supreme Court is very protective of speech, including commercial speech. Threats to commercial speech persist nonetheless. This article briefly examines two: the use of commercial speech restrictions as a form of rent-seeking, and compelled commercial speech. Regulation of commercial speech is sometimes used to protect established corporate interests from competitors who are less able to bear the costs of regulation, with consequences that extend beyond the economic marketplace. In the case of commercial speech, courts have also been unduly deferential to claims of a consumer “right to know” as a basis for mandated labeling and disclosure. Greater and …

Responses To Familiar And Unfamiliar Humans By Belugas (Delphinapterus Leucas), Bottlenose Dolphins (Tursiops Truncatus), & Pacific White-Sided Dolphins (Lagenorhynchus Obliquidens): A Replication And Extension, Heather M. Hill, Deirdre Yeater, Sarah Gallup, Sara Guarino, Steve Lacy, Tricia Dees, Stan A. Kuczaj Ii

Psychology Faculty Publications

Previous research has documented that cetaceans can discriminate between humans, but the process used to categorize humans still remains unclear. The goal of the present study was to replicate and extend previous work on the discrimination between familiar and unfamiliar humans by three species of cetaceans. The current study manipulated the familiarity and activity level of humans presented to 12 belugas (Delphinapterus leucas) housed between two facilities, five bottlenose dolphins (Tursiops truncatus), and six Pacific white-sided dolphins (Lagenorhynchus obliquidens) during free-swim conditions. Two measures of discrimination were coded from video recordings of each trial: …

Cat Cafe V. Yahoo Center, California Superior Court

Historical and Topical Legal Documents

No abstract provided.

The Problems Of False Comparions: Animal Discourse And The Anti-Choice Movement, Nicole Power

Dalhousie Journal of Legal Studies

Advocacy for the protection of animal welfare and women’s right to reproductive choice have little, if anything, in common. It is productive, then, to question the recurring association of these unrelated ethical issues. If one feels compassion for the plight of the nonhuman animal, the argument goes, then it is morally inconsistent to neglect the fetus. An understanding of the incongruous political contexts at play between abortion and animal welfare effectively repudiates this argument, but a more important question must be answered: why is this strange argument so pervasive? In brief, it is the uniform legal marginalization of women and …

Geographically Isolated Wetlands Are Part Of The Hydrological Landscape, Mark Rains, S. G. Leibowitz, M. J. Cohen, I. F. Creed, H. E. Golden, J. W. Jawitz, P. Kalla, C. R. Lane, M. W. Lang, D. L. Mclaughlin

School of Geosciences Faculty and Staff Publications

No abstract provided.

The Original Fourth Amendment, Laura K. Donohue

Georgetown Law Faculty Publications and Other Works

The meaning of the rights enshrined in the Constitution provide a critical baseline for understanding the limits of government action—perhaps nowhere more so than in regard to the Fourth Amendment. At the time of the Founding, the Fourth Amendment prohibited the government from entering into any home, warehouse, or place of business, against the owner’s wishes, to search for or to seize persons, papers, and effects, absent a specific warrant. The only exception was when law enforcement or citizens were in active pursuit of a felon.12 Outside of that narrow circumstance, the government was prohibited from search and seizure absent …

Mirabile Dictu: The Bryn Mawr College Library Newsletter 19 (2016), Bryn Mawr College Library

Mirabile Dictu: Newsletter of the Bryn Mawr College Libraries

No abstract provided.

Compelled Commercial Speech And The Consumer "Right To Know", Jonathan H. Adler

Faculty Publications

Compelled commercial speech, including mandatory labeling and the disclosure of factually true information, should not be seen as a separate category of speech under the First Amendment. Rather, compelled commercial speech should be understood as a type of commercial speech and be subject to the same level of protection as commercial speech generally. Accordingly, commercial speech compulsions, such as mandatory disclosures and labeling requirements, must be supported by a substantial government interest under the Central Hudson framework. The assertion of a consumer “right to know” does not constitute such an interest and cannot, by itself, justify compelled commercial speech within …

The Case Of The {-Th} Plural In The Earliest Text, Stanford Carmack

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

The earliest text of the Book of Mormon employs the {-th} plural — for example, “Nephi’s brethren rebelleth” — in a way that is substantially similar to what is found in many writings of the Early Modern period. The earliest text neither underuses nor overuses the construction, and it manifests inflectional variation and differential usage rates typical of Early Modern English. The totality of the evidence tells us that the Book of Mormon is most reasonably classified as a 16th- or 17th-century text, not as a 19th-century text full of biblical hypercorrections.