Digital Commons Network^™

Expanding Pulmonary Rehabilitation Access With Technology, Erica Mccarron Anderson

All ETDs from UAB

ii EXPANDING PULMONARY REHABILITATION WITH TECHNOLOGY ERICA MCCARRON ANDERSON COMMUNITY HEALTH & HUMAN SERVICES ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is a major cause of mortality and morbidity in the United States. COPD is a chronic, progressive lung disease characterized by irreversible airway obstruction. Symptoms include fatigue, chronic cough, excess mucus production and shortness of breath. These symptoms often impair quality-of-life. There are many interventions aimed at improving health related qualityof- life for patients living with COPD. Pulmonary rehabilitation is a multidisciplinary program exercise, education and psychosocial support. Pulmonary rehabilitation is well established to decrease symptoms in all stages of …

Establishing And Organ Culture To Study Scleral Collagen Remodeling In Myopia, Sarah Baldivia

All ETDs from UAB

The purpose of this study was to evaluate whether quantitative ultrasound (QUS)

Fcrl5 Counter-Regulates Natural And T Cell-Independent Immunoglobulin Production By Innate-Like B Cells, Eugene John Becker

All ETDs from UAB

At homeostasis and during the initial phases of primary responses to pathogens, humoral host defense is chiefly coordinated by specialized B cells known as splenic marginal zone (MZ) and body cavity-derived B-1 B cells. These front line immune mediators are termed “innate like” due to their ability to secrete broadly-reactive natural antibodies and respond rapidly to antigens in a T cell-independent manner. The production of natural antibodies possessing specificities for self-antigens allows clearance of cellular debris, maintenance of homeostasis and protection from infections that can also predispose the host to immunological disease. However, how the functions of these specialized cells …

Meta-Analysis Of Cognitive Performance In Fibromyalgia, Tyler Reed Bell

All ETDs from UAB

Fibromyalgia is a disease that encompasses difficulties with pain, physical function, and emotion, but is also characterized by complaints of poor cognition. Over the last two decades, a vast amount of literature has tested for cognitive differences between individuals with and without fibromyalgia. The purpose of the current study was to conduct a quantitative synthesis on these differences across multiple cognitive domains. After a systematic search of eligible studies, random-effect meta-analyses were conducted on effect sizes (Hedges’ g) derived from 37 cross-sectional studies covering domains of processing speed, memory and executive function. Participants included persons with fibromyalgia (total n = …

Ribosomal Protein L12 (Rpl12) As A Novel Target In Cystic Fibrosis, Kathryn E. Oliver

All ETDs from UAB

Approximately 1,000 new cases of cystic fibrosis (CF) are diagnosed in the United States every year. The disease is caused by over 1,700 naturally occurring variants in the CF transmembrane conductance regulator (CFTR). Defects in the CFTR coding sequence contribute to variable disease severity in the patient population. The majority of individuals born with CF harbor at least one specific mutation in CFTR termed F508del. Clinical manifestations of CF include severe damage of multiple exocrine tissues, including the lungs, intestine, pancreas, reproductive and other organ systems. An overarching goal of our work is to identify cellular targets that contribute to …

Regulation Of The Mitochondrial Thiol Network With Targeted Electrohpiles, Matthew Ryan Smith

All ETDs from UAB

Cells possess a remarkable plasticity to alter their metabolism and change their function based on stimuli within their resident microenvironment. The mitochondria within these cells utilize a variety of sources such as pyruvate, glutamine, or fatty acids in order to generate metabolites, amino acids, and reducing equivalents needed for cellular proliferation.Many mitochondrial enzymes possess contain a cysteine which possesses a thiol group, a unique redox-signaling moiety that can be activated under specific circumstances by bio-reactive compounds forming a network of mitochondrial proteins which are responsible for mitochondrial respiration. However, it is unknown whether targeting these reactive thiol groups present a …

A Vous De Amatongas: The Voice Of Amatongas, Matthew T. Adler

Honors Capstones

No abstract provided.

Analysis Of The Ciliary Genes Gas8 And Mks6 Reveal Conserved Roles In Cilia Motility And Transition Zone Function, Wesley Robert Lewis

All ETDs from UAB

Cilia are microtubule based cellular appendages that are present throughout the hierarchy of the animal kingdom. These appendages are utilized for a wide array of functions such as motility in single celled organisms to coordinating complex cellular signaling pathways in more complex organisms. Though these appendages are well conserved, the exact function of cilia in many cell types remains unknown. Recently, cilia are tied to a myriad of developmental diseases and diseases of adult homeostasis collectively referred to as ciliopathies. Dysfunction in cilia results in a wide array of phenotypes ranging from retinal degeneration to polydactyly, cystic kidney disease, and …

Soft Robotic Grippers For Biological Sampling On Deep Reefs, Kevin C. Galloway, Kaitlyn P. Becker, Brennan Phillips, Jordan Kirby, Stephen Licht, Dan Tchernov, Robert J. Wood, David F. Gruber

Ocean Engineering Faculty Publications

This article presents the development of an underwater gripper that utilizes soft robotics technology to delicately manipulate and sample fragile species on the deep reef. Existing solutions for deep sea robotic manipulation have historically been driven by the oil industry, resulting in destructive interactions with undersea life. Soft material robotics relies on compliant materials that are inherently impedance matched to natural environments and to soft or fragile organisms. We demonstrate design principles for soft robot end effectors, bench-top characterization of their grasping performance, and conclude by describing in situ testing at mesophotic depths. The result is the first use of …

Sequential Release Of Nanoparticle Payloads From Ultrasonically Burstable Capsules, Stephen Kennedy, Jennifer Hu, Cathal Kearney, Hadas Skaat, Luo Gu, Marco Gentili, Herman Vandenburgh, David Mooney

Electrical, Computer, and Biomedical Engineering Faculty Publications

In many biomedical contexts ranging from chemotherapy to tissue engineering, it is beneficial to sequentially present bioactive payloads. Explicit control over the timing and dose of these presentations is highly desirable. Here, we present a capsule-based delivery system capable of rapidly releasing multiple payloads in response to ultrasonic signals. In vitro, these alginate capsules exhibited excellent payload retention for up to 1 week when unstimulated and delivered their entire payloads when ultrasonically stimulated for 10–100 s. Shorter exposures (10 s) were required to trigger delivery from capsules embedded in hydrogels placed in a tissue model and did not result in …

Analysis Of Force Production By A Biologically Inspired Underwater Flapping Foil Near Solid Boundaries In Three Dimensional Flow, Dane Elles

Open Access Master's Theses

Force production from an underwater flapping foil near a solid boundary was experimentally studied in order to characterize the three dimensional flow effects. The experimental apparatus consisted of a dual canister system that actuated a harmonic oscillation of a NACA 0012 rectangular planform foil in pitch and roll. The flapping foil was towed at constant velocity through water in a tow tank in both a freestream and near boundary condition while forces and torques were measured by a six axis dynamometer. Experimental tests showed that for the chosen kinematic conditions and foil geometry, average maximum instantaneous lift forces increased 16-29% …

Description Of Two New Species Of The Neotropical Genus Yphthimoides Forster, 1964 (Lepidoptera: Nymphalidae: Satyrinae) From The ‘Renata Clade’, Eduardo Barbosa, Mario Marín, Carlos Eduardo Giraldo, Sandra Uribe, André Freitas

Neotropical Biodiversity

This paper describes two new species of Neotropical butterflies: Yphthimoides blanquita Barbosa, Marín and Freitas sp. nov., from the dry forest of northwestern Colombia, and Yphthimoides nareta Barbosa & Freitas sp. nov. from northeastern Brazil, based on morphological and molecular data. Adult morphology, including wing shape and pattern as well as male genitalia, is described in detail. Furthermore, analysis of the mitochondrial CoxI ‘barcode’ showed that both new species are quite distinct from all similar Yphthimoides species and additionally, the ‘renata clade’ is defined based on the presence of cornuti in the aedeagus.

Freshwater Vertebrate And Invertebrate Diversity Patterns In An Andean-Amazon Basin: Implications For Conservation Efforts, Janeth Lessmann, Juan M. Guayasamin, Kayce L. Casner, Alexander S. Flecker, W. Chris Funk, Cameron K. Ghalambor, Brian A. Gill, Iván Jácome-Negrete, Boris C. Kondratieff, Leroy N. Poff, José Schreckinger, Steven A. Thomas, Eduardo Toral-Contreras, Kelly R. Zamudio, Andrea C. Encalada

Neotropical Biodiversity

The Napo Basin in Ecuador is an important drainage of the Amazon Basin, the most biodiverse ecosystem for freshwater species. At the same time, this basin has conspicuous information gaps on its biodiversity patterns and human threats. Here, we estimated the diversity distribution patterns of freshwater vertebrates and invertebrates in the Napo Basin, as a tool for present and future management and conservation efforts. Also, we assessed the spatial congruence of the diversity patterns observed between aquatic vertebrates and invertebrates. For this, we compiled occurrence records for 481 freshwater vertebrate species (amphibians, birds, mammals, reptiles, and fish), and 54 invertebrate …

The Decline Of Professionalism, Rebecca Roiphe

Articles & Chapters

Traditionally, professionalism conceived of the professions as central to democratic society. Because professionals gained their status through reputation not wealth, they were in the best position to suppress their own self-interest in order to ascertain and pursue the public good. This Article argues that this traditional understanding of the professions was lost as a market ideology took hold in the 1970s. Professionalism gradually became synonymous with the delivery of services. This Article draws on this intellectual history to argue that aspects of the traditional concept of professionalism can and should be revived today.

Multiple Lines Of Evidence Support The Species Status Of The Poorly Known Diasporus Tigrillo And The Recently Described Diasporus Citrinobapheus (Anura: Eleutherodactylidae), Adrián García-Rodríguez, Erick Arias, Gerardo Chaves

Neotropical Biodiversity

The genus of direct-developing frogs Diasporus is currently composed of 11 species ranging from Honduras to Ecuador. Body size variability, advertisement call divergence, and polychromatism have all been reported at the interpopulation level, suggesting that the existence of some species may be masked within the current nomenclature of this group. This pattern highlights the need for integrative approaches to resolve the taxonomy of the genus and provide a robust delimitation of the species it contains. Here, we provide novel data on morphology, genetics, habitat use, and bioacoustics for D. tigrillo, the least known species in the genus. Then we use …

An Assessment Of The Populations Of Sylvilagus Brasiliensis Andinus In Páramos With Different Vegetation Structures In The Northeastern Andes Of Ecuador, Juanita García, Esteban Suárez, Galo Zapata-Ríos

Neotropical Biodiversity

For the first time in Ecuador, a defecation rate is calculated from three captured páramo rabbit Sylvilagus brasiliensis andinus individuals. Combining this defecation rate, the pellet count method, and Novaro et al.'s (1992) hare density equation, páramo rabbit densities were calculated in four páramo localities with different vegetation structures. A correlation was found between the páramos' vegetation diversity and páramo rabbit densities. This study shows that pellet counting is an economical and non-invasive method that permits the estimation of páramo rabbit abundances in páramo ecosystems. Páramo rabbit abundances may serve as a tool to measure the effects of human activity …

First Record Of A Hybodont Shark (Chondrichthyes: Hybodontiformes) From The Lower Cretaceous Of Colombia, Jorge D. Carrillo-Briceño, Edwin A. Cadena, Alex T. Dececchi, Hans C. E. Larson, Trina Y. Du

Neotropical Biodiversity

The Mesozoic chondrichthyan fossil record from northern South America is scarce and poorly known containing only a few reports of lamniform and ptychodont species from the Upper Cretaceous of Colombia and Venezuela. Here, we report the discovery of two associated (found together) dorsal fin spines of a hybodont shark from the Valanginian deposits of the Rosablanca Formation (Andes of Colombia). This hybodont along with the presence of ammonites and other mollusks, turtles, plesiosaurs and ichthyosaurs support a marine depositional environment for this geological unit. Although both spines described here are fragmentary and without diagnostic characters to allow identification to generic …

A Comparison Between Shale Gas In China And Unconventional Fuel Development In The United States: Water, Environmental Protection, And Sustainable Development, Paolo D. Farah, Riccardo Tremolada

Brooklyn Journal of International Law

China is believed to have the world's largest exploitable reserves of shale gas, although several legal, regulatory, environmental, and investment-related issues will likely restrain its exploitation. China's capacity to face these hurdles successfully and produce commercial shale gas will have a crucial impact on the regional gas market and on China’s energy mix, as Beijing strives to decrease reliance on imported oil and coal, and, at the same time, tries to meet growing energy demand and maintain a certain level of resource autonomy. The development of the unconventional natural gas extractive industry will also provide China with further negotiating power …

The Phase-Out And Sunset Of Travel Restrictions In The International Health Regulations, Sarah R. Goldfarb

Brooklyn Journal of International Law

Whether and to what extent travel restriction should be implemented during international infectious disease epidemics became a controversial issue, most recently, during the 2014 Ebola outbreak. The primary authority on the manner in which to respond to such epidemics is the International Health Regulations (IHR). The IHR is a treaty, established by the World Health Organization (WHO), which governs and coordinates international responses to international infectious disease epidemics. Despite the WHO's strong advisement to the contrary, many countries who were signatories to the IHR implemented travel bans and other types of travel restrictions to prevent the transmission of the disease …

“Chi S’Aiuta, Dio L’Aiuta”: Balancing Italy’S Right To Utilize Assisted Reproductive Technologies With The Teachings Of The Catholic Church, Erin A. Mcmullan

Brooklyn Journal of International Law

Adelina Parrillo never anticipated starting a prolonged legal battle when she requested her embryos be donated for scientific research. The restrictive legislation in place in Italy, inevitably influenced by the Catholic Church, mandated that she either implant the embryos or store them indefinitely. After a long drawn out battle with the Italian courts, she desperately sought assistance from the European Court of Human Rights (ECtHR), a court tasked with protecting the rights of individuals such as Parrillo from the overreaching of Member States. The ECtHR) acknowledged that this decision, to donate her unused embryos to medical research, was within the …

Trespass, Veronika Ivanova

University Honors Theses

Controversial artworks are relentlessly defended by art critics, who frequently downplay their disturbing emotional affect. Against an overwhelming consensus to the contrary, this essay will propose that ethical analysis is an effective and critically revealing method of engaging with contemporary transgressive art. It will argue that in favoring conceptual rather than emotional reactions, commentators fail to fully engage with the work they promote. Far from clouding our judgement, shame, outrage, and revulsion are the very emotions that artworks can set out to evoke. I am specifically interested in artists that challenge the attitude of aesthetic disinterestedness through engaging our moral …

Clerical Leadership In Late Antiquity: Augustine On Bishops’ Polemical And Pastoral Burdens, Peter Iver Kaufman

Jepson School of Leadership Studies articles, book chapters and other publications

Augustine returned from Italy to North Africa in 388, apparently elated to have found his calling. The cities he had known, Thagaste and Carthage, and would soon come to know, Hippo Regius, were relatively prosperous, despite taxes collected for the central government which had been making increasing demands since the time of Emperor Constantine. The funds available for municipal improvements were depleted (gravement amputés), Claude Lepelley calculated, siting the African cities in “a history of inexorable decline” from the 380s into the 430s. In the coastal city of Hippo, however, Augustine, as bishop was busy from the late 390s, exchanging …

Solidifying Segregation Or Promoting Diversity? School Closure And Rezoning In An Urban District, Thomas J. Shields

Jepson School of Leadership Studies articles, book chapters and other publications

Purpose: Layered with myriad considerations, school closure and rezoning processes in urban school systems are politically fraught with the potential for damaging consequences. This article explores the politics and impacts of a closure and rezoning process in Richmond, Virginia, through the lens of themes applicable to urban school systems and students across the nation. These include the intersection of closure and rezoning with growing White reinvestment in urban school systems, as well as the importance of focusing on diversity and equity during a time of intense pressure to close schools.

Research Methods/Approach: Drawing on the case of Richmond, Virginia, we …

Applying Deception Detection To True And False Confessions: A Novel Approach To Conducting Experiments In Legal Psychology, Olivia Preston

University Honors Theses

Recent exonerations of convicted defendants by the efforts of advocates like the Innocence Project are accompanied by a concerning finding that a large proportion of defendants had falsely confessed to the alleged crime. False convictions result in due process violations and the suffering and stigma of the convicted and their families, in addition to imposing an economic burden on the community. Prior research has identified structural interrogation practices and individual characteristics that increase risk of false confessions, however knowledge on how to identify true and false confessions is minimal and undeveloped. Cues to deception in false statements may be an …

Migration Movement, Robert Porte

University Honors Theses

All†Borders†Are†Temporary

"Migration is a phenomenon, not a problem – something that simply is. The right to migrate and to move freely is our human right. When societies restrict or choke off the movements of their citizens, they end up doing the work of a dam, they generate power and control floods, but in doing so they destroy life and wreck the surrounding space."

Justseeds†(excerpt)

As the current administration at the time of this writing continues its program of deportation of women and children from the U.S. to their war torn and violent countries of origin, I want not to engage …

Insuring Takings Claims, Christopher Serkin

Vanderbilt Law School Faculty Publications

Local governments typically insure themselves against all kinds of losses, from property damage to legal liability. For small- and medium-sized governments, this usually means purchasing insurance from private insurers or participating in municipal risk pools. Insurance for regulatory takings claims, however, is generally unavailable. This previously unnoticed gap in municipal insurance coverage could lead risk averse local governments to underregulate and underenforce existing regulations where property owners threaten to bring takings claims. This seemingly technical observation turns out to have profound implications for theoretical accounts of the Takings Clause that focus on government regulatory incentives. This Article explores the impact …

Tourism And "Quality Of Life" At The End Of Franco's Dictatorship, Eugenia Afinoguénova

Spanish Languages and Literatures Research and Publications

No abstract provided.

Confounding Ockham's Razor: Minilateralism And International Economic Regulation, Eric C. Chaffee

Brooklyn Journal of Corporate, Financial & Commercial Law

In Minilateralism: How Trade Alliances, Soft Law, and Financial Engineering Are Redefining Economic Statecraft, Professor Chris Brummer embraces the complexity of the global economic system and its regulation by exploring the emerging role and dominance of varying strands of economic collaboration and regulation that he collectively refers to as “minilateralism.” In describing the turn toward minilateralism, Brummer notes a number of key features of this new minilateral system, including a shift away from global cooperation to strategic alliances composed of the smallest group necessary to achieve a particular goal, a turn from formal treaties to informal non-binding accords and other …

The Customer's Nonwaivable Right To Choose Arbitration In The Securities Industry, Jill I. Gross

Brooklyn Journal of Corporate, Financial & Commercial Law

Arbitration has been the predominant form of dispute resolution in the securities industry since the 1980s. Virtually all brokerage firms include predispute arbitration agreements (PDAAs) in their retail customer contracts, and have successfully fought off challenges to their validity. Additionally, the industry has long mandated that firms submit to arbitration at the demand of a customer, even in the absence of a PDAA.

More recently, however, brokerage firms have been arguing that forum selection clauses in their agreements with sophisticated customers (such as institutional investors and issuers) supersede firms’ duty to arbitrate under FINRA Rule 12200. Circuit courts currently are …

Standing Up For Their Data: Recognizing The True Nature Of Injuries In Data Breach Claims To Afford Plaintiffs Article Iii Standing, Andrew Braunstein

Journal of Law and Policy

Over the last several years, data breaches have become increasingly more common, due in no small part to the failures of organizations charged with storing and protecting personal data. Consumers whose data has fallen victim to these breaches are more often turning to federal courts in attempts to be made whole from the loss of their information, whether simple credit card information or, as breaches become more sophisticated, social security information, medical and financial records, and more. These consumers are often being turned away from the courthouse, however, due to a failure of many federal courts to find that the …