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Flexible Needle-Tissue Interaction Modeling With Depth-Varying Mean Parameter: Preliminary Study, Kai Guo Yan, Tarun Podder, Yan Yu, Tien-I Liu, Christopher W.S. Cheng, Wan Sing Ng

Bodine Journal

Flexible needle steering has aroused a lot of research interest in recent years. It has the potential to correct targeting errors, which may be caused by needle bending, tissue deformation, or error in insertion angle. In addition, control and planning based on a steering model can guide the needle to some areas that are currently not amenable to needles because of obstacles, such as bone or sensitive tissues. Thus, there is a clear motivation for needle steering. In this paper, a spring–beam– damper model is proposed to describe the dynamics during the needle–tissue contact procedure. Considering tissue inhomogeneity, depth-varying mean …

Combination Of Vandetanib, Radiotherapy, And Irinotecan In The Lovo Human Colorectal Cancer Xenograft Model, Phyllis Wachsberger, Phd, Randy Burd, Phd, Anderson Ryan, Phd, Constantine Daskalakis, Phd, Adam Dicker Md, Phd

Bodine Journal

Purpose:

The tumor growth kinetics of the human LoVo colorectal xenograft model was assessed in response to vandetanib, an orally available receptor tyrosine kinase inhibitor, radiotherapy (RT), or irinotecan (CPT-11), as single therapies and in combination.

Methods and Materials:

LoVo cells were injected subcutaneously into the right hind limb (5x106 cells in 100μL phosphate-buffered saline) of athymic NCR NUM mice and tumors were grown to a volume of 200–300mm3 before treatment. Vandetanib was administered at 50 mg/kg daily orally for 14 days starting on Day 1. RT was given as three fractions (3x3 Gy) on Days 1, 2, and 3. …

Nuclear Factor Κb Inhibitors Alleviate And The Proteasome Inhibitor Ps-341 Exacerbates Radiation Toxicity In Zebrafish Embryos, Borbala Daroczi, Gabor Kari, Qing Ren, Adam Dicker Md, Phd, Ulrich Rodeck

Bodine Journal

Inflammatory changes are a major component of the normal tissue response to ionizing radiation, and increased nuclear factor κB (NF-κB) activity is an important mediator of inflammatory responses. Here, we used zebrafish embryos to assess the capacity of two different classes of pharmacologic agents known to target NF-κB to modify radiation toxicity in the vertebrate organism. These were proteasome inhibitors, including lactacystin, MG132, and PS-341 (Bortezomib/VELCADE), and direct inhibitors of NF-κB activity, including ethyl pyruvate (EP) and the synthetic triterpenoid CDDO-TFEA (RTA401), among others. The proteasome inhibitors either did not significantly affect radiation sensitivity of zebrafish embryos (MG132, lactacystin) or …

Rhode Island State Council On The Arts (1979-1992): Booklet 04

Rhode Island State Council on the Arts (1979-1992)

No abstract provided.

Tungstate (Vi) Sorption On Hematite: An In Situ Atr-Ftir Probe On The Mechanism, Sudipta Rakshit, Bryan Sallman, Athénais Davantés, Grégory Lefèvre

Agricultural and Environmental Sciences Faculty Research

Owing to the suspected toxicity and carcinogenicity of tungstate (VI) oxyanions [i.e. mono tungstate and several polytungstate, generally represented by W (VI)], the environmental fate of W (VI) has been widely studied. Sorption is regarded as a major mechanism by which W (VI) species are retained in the solid/water interface. Iron (hydr)oxides have been considered important environmental sinks for W (VI) species. Here we report sorption mechanisms of W (VI) on a common iron oxide mineral-hematite under environmentally relevant solution properties using in situ attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopic probes. Initial W (VI) loadings varied from 10 …

Prospectus, November 9, 2016, Peter Floess, Scott Wells, Matt Moss, Dylan Kleiss, Ryan Mills

Prospectus 2016

RADIO DRAMA BY COMM. STUDENTS TO AIR ON WPCD; Humans of Parkland: Thom Schnarre; Club Latino a 'family-like community'; Official: 40 to 50 buildings damaged in Oklahoma quake; Parkland Cobra soccer teams 2016; Reasons to go to China; Obama reveals private living areas of White House; Register for Parkland College Spring 2017 Classes; Google speaker is secretary, radio...and work in progress; Students from Okinawa, Japan visit Parkland

The Murray Ledger And Times, November 9, 2016, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Anderson County - Place Names, Robert M. Rennick

Robert M. Rennick Manuscript Collection

Place names for Anderson County, Kentucky.

Mesenteric Vascular Dysregulation And Intestinal Inflammation Accompanies Experimental Spinal Cord Injury, Emily Swartz Besecker, Gina M. Deiter, Nicole Pironi, Timothy K. Cooper, Gregory Michael Holmes

Health Sciences Faculty Publications

Cervical and high thoracic spinal cord injury (SCI) drastically impairs autonomic nervous system function. Individuals with SCI at thoracic spinal-level 5 (T5) or higher often present cardiovascular disorders that include resting systemic arterial hypotension. Gastrointestinal (GI) tissues are critically dependent upon adequate blood flow and even brief periods of visceral hypoxia triggers GI dysmotility. The aim of this study was to test the hypothesis that T3-SCI induces visceral hypoperfusion, diminished postprandial vascular reflexes and concomitant visceral inflammation. We measured in vivo systemic arterial blood pressure and superior mesenteric artery (SMA) and duodenal blood flow in anesthetized T3-SCI rats at 3 …

Montana Kaimin, November 9-15, 2016, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Gelver Martinez V. Bank Of America Na

2016 Decisions

USDC for the District of New Jersey

Spectator 2016-11-09, Editors Of The Spectator

The Spectator

No abstract provided.

Daily Eastern News: November 09, 2016, Eastern Illinois University

November

No abstract provided.

Influence Of Anterior Thalamic Inactivation On The Retrieval Of Spatial Reference Memory And Working Memory In The Radial Arm Maze, Ryan E. Harvey

Psychology ETDs

Previous studies have shown that the anterior thalamic nuclei (ATN) contain a large population of head direction cells, which fire as a function of an animal’s directional orientation in an environment, thereby providing a compass-like representation guiding navigation. Recent work has suggested that directional orientation information stemming from the ATN is critical for the generation of hippocampal and parahippocampal spatial representations, and may contribute to the establishment of unique spatial representations in radially oriented tasks such as the radial arm maze. While studies have confirmed that ATN lesions impair the acquisition of new spatial information in variants of the radial …

The Antelope, University Of Nebraska At Kearney

The Antelope

No abstract provided.

Whalesong 2016-11-09, N/A N/A

Whalesong

No abstract provided.

Volume 112 Issue 10, Southwestern Oklahoma State University

The Southwestern - Archive

No abstract provided.

Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved In Immunity And Neurogenesis In Simian Immunodeficiency Virus-Infected Macaques, John K Maxi, Matt Dean, Jovanny Zabaleta, Krzysztof Reiss, Gregory J. Bagby, Steve Nelson, Peter J. Winsauer, Francesca Peruzzi, Patricia E. Molina

School of Graduate Studies Faculty Publications

Alcohol use disorders (AUD) exacerbate neurocognitive dysfunction in Human Immunodeficiency Virus (HIV+) patients. We have shown that chronic binge alcohol (CBA) administration (13-14 g EtOH/kg/wk) prior to and during simian immunodeficiency virus (SIV) infection in rhesus macaques unmasks learning deficits in operant learning and memory tasks. The underlying mechanisms of neurocognitive alterations due to alcohol and SIV are not known. This exploratory study examined the CBA-induced differential expression of hippocampal genes in SIV-infected (CBA/SIV+; = 2) macaques in contrast to those of sucrose administered, SIV-infected (SUC/SIV+; = 2) macaques. Transcriptomes of hippocampal samples dissected from brains obtained at necropsy (16 …

Effect Of Manganese Chloride (Mncl2) On Peroxidase Activity In Labeo Rohita, Nadia Altaf, Muhammad Javed, Sidra Abbas

Journal of Bioresource Management

Four groups (n=10) of one year old Labeo rohita were exposed to 96-hr LC50 and sub-lethal (2/3rd, 1/4th and 1/5th) concentrations of MnCl2 for a duration of 30 days in the glass aquaria of 50L water capacity. After an exposure period of 30 days, the activity of peroxidase enzyme in the liver and brain of MnCl2 exposed fish was measured and compared with the control group. Physico-chemical parameters of the test media, viz. pH, dissolved oxygen, carbon dioxide, total ammonia, total hardness, calcium and magnesium were also monitored on a 12 hour basis during the whole experimental duration by following …

Spectrum, Volume 37, Issue 8, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: FBI concludes Clinton email case closed -- Students attend Lead365 conference -- Gaming and computer science programs rated by Princeton review -- Pioneer Players' improve showcase -- Men's and woman's basketball preparing for season -- Rowing tops Fairfield in SHU Scare Dual meet -- X-men rugby win Tri-state Conference Championship

Physiological Response Of Tamarix Ramosissima (Tamaricaceae) To A Biological Control Agent, Evan B. Craine, Ann Evankow, Katherine Bibee Wolfson, Kathryn Dalton, Holly Swedlund, Casey Bowen, M. Shane Heschel

Western North American Naturalist

Within the last century, the floristic composition of riparian communities in the Southwest has drastically changed following introduction of the exotic tree Tamarix ramosissima. In an attempt to control Tamarix populations, the tamarisk leaf beetle (Diorhabda carinulata) has been utilized as a biological control agent. Three years of data collection at our study sites along Fountain Creek (Fountain, CO) allowed us to characterize the response of Tamarix to invasion by the biological control agent. In analyzing data collected before, during, and after the beetle invasion, we observed a significant effect of foliar herbivory on Tamarix physiology and life …

Evidence For The Validity Of Protatlanta Sculpta (Gastropoda: Pterotracheoidea), D Wall-Palmer, Ak Burridge, Ktca Peijnenburg, A Janssen, E Goetze, R Kirby, Mb Hart, Cw Smart

School of Geography, Earth and Environmental Sciences

No abstract provided.

The Vengekeep Prophecies #2: The Shadowhand Covenant, Cynthia Frazier

Children's Book and Media Review

Jasper Grimjax is entangled in another mystery. This one involves a secret society of master thieves that have disappeared, the unsolved theft of valuable relics, fantastical and deadly monsters, traps, ambushes, and magical potions along with tricks and cons. Thrown into the mix is Jasper’s former friend, Maloch, who likes to show his superiority in every way, and a brother and sister trying to get their parents out of prison for crimes they did not commit. Adventures abound as these four use their wits to solve the puzzle before it is too late.

Tractor Mac: Harvest Time, Cynthia Frazier

Children's Book and Media Review

Life on a farm in the autumn is a busy time. The farm across the road from Stony Meadow is having its annual Pumpkin Picking Festival. Families come every year to pick out their pumpkins, ride on a hay wagon, guess the largest pumpkin’s weight, find their way through the maze, and eat yummy food. All of the animals on the farms are excited about the season also. But Mac and Small Fred, tractors on neighboring farms aren’t so excited. Small Fred is worried that pulling the heavy wagon full of pumpkins will be too much for him this year. …

Nancy Drew And Her Biggest Case Ever, Rebeca Wallin

Children's Book and Media Review

“When kidnapped, I am often reminded that a sack over your head, a gag in your mouth, or rope around your wrists are anything but fashionable.” Detective Nancy Drew offers this and many other pearls of wisdom to the audience throughout Nancy Drew and Her Biggest Case Ever. This mystery as per usual features hidden doorways, kidnapping, a questionable will, supposed ghosts, and cut phone lines. Nancy works to help two recently orphaned girls who have doubts about their new guardian who is appropriately mysterious and brooding. In the course of her sleuthing Nancy discovers a treasure map, an imposter, …

My Bike, Jacquelin Marrero

Children's Book and Media Review

The main character Tom is on his way to work and although the title refers to his bike, the story actually is about how he uses it to get there. He chooses to ride a bike and describes it, and further describes everything he sees along the way on his path. Tom passes multiple types of vehicles, circus animals, and other things as well. Once he arrives at work, he also describes how he gets ready and what he does in the circus.

Little Bunny, Tracy Adler

Children's Book and Media Review

Bunnies are known for being very energetic and hopping all around. In this story a baby bunny explores the world outside of its den. He gets into trouble, he experiences different textures, sounds, and nature all in a solitary day. No one is able to get him to calm down and stop running around except for his mother. When she calls him home he relaxes and tells her about his long but fruitful day.

Hedgehug's Halloween, Cynthia Phillips

Children's Book and Media Review

Hedgehug the hedgehog has been invited to a Halloween party, but wait--is that tonight?! He has forgotten all about it and has nothing to wear to the costume party! It’s okay his friends are there to help him find a costume. The only problem is that no matter how clever the costume Hedgehug’s spines keep ruining it. Is it time to just give up and go home? No way, Hedgehug’s friends come through for him in the end with the perfect costume. The party is a huge success thanks to his friends.

Gris Grimly's Tales From The Brothers Grimm, Carlie Smith

Children's Book and Media Review

Jacob and Wilhelm Grimm cataloged a treasure trove of European folktales that are brought to new life in this edition. Old favorites like Rapunzel, Hansel and Gretel, The Elves and the Shoemaker, and Cinderella all make an appearance. Just as intriguing are the lesser known heroes like the princess without hands, the woman who disobeyed the Virgin Mary, and the vast array of animals who form bands, proclaim popes, and search for true love. Perhaps they may appear strange to some readers because the stories are less common, but in many cases these tales have familiar morals and magic. This …

Responding To Modern Flooding: Old English Place-Names As A Repository Of Traditional Ecological Knowledge, Richard L.C. Jones

Journal of Ecological Anthropology

Place-names are used to communicate Traditional Ecological Knowledge (TEK) by all indigenous, aboriginal and First Nations people. Here and for the first time, English place-names are examined through a TEK lens. Specifically, place-names formed in Old English—the language of the Anglo-Saxon—and coined between c. 550 and c. 1100 A.D., are explored. This naming horizon provides the basic name stock for the majority of English towns and villages still occupied today. While modern English place-names now simply function as convenient geographical tags Old English toponymy is shown here to exhibit close semantic parallels with many other indigenous place-names around the world. …