Emanata Presents: Kin (2016)

Emanata, 2014-

Started by illustrator and comics artist Chris Kindred in 2014 with Weird, Vol. 1, Emanata is VCU’s first-ever comics anthology.

De Novo Genome Assembly Of Geosmithia Morbida, The Causal Agent Of Thousand Cankers Disease, Taruna A. Schuelke, Anthony Westbrook, Kirk Broders, Keith E. Woeste, Matthew D. Macmanes

Department of Forestry & Natural Resources Faculty Publications

Geosmithia morbida is a filamentous ascomycete that causes thousand cankers disease in the eastern black walnut tree. This pathogen is commonly found in the western U.S.; however, recently the disease was also detected in several eastern states where the black walnut lumber industry is concentrated. G. morbida is one of two known phytopathogens within the genus Geosmithia, and it is vectored into the host tree via the walnut twig beetle. We present the first de novo draft genome of G. morbida. It is 26.5 Mbp in length and contains less than 1% repetitive elements. The genome possesses an …

Changes In The Proteome Of Langat-Infected Ixodes Scapularis Ise6 Cells: Metabolic Pathways Associated With Flavivirus Infection, Jeffrey M. Grabowski, Rushika Perera, Ali M. Roumani, Victoria E. Hedrick, Halina Dorota Inerowicz, Catherine A. Hill, Richard Kuhn

Department of Entomology Faculty Publications

Background: Ticks (Family Ixodidae) transmit a variety of disease causing agents to humans and animals. The tick-borne flaviviruses (TBFs; family Flaviviridae) are a complex of viruses, many of which cause encephalitis and hemorrhagic fever, and represent global threats to human health and biosecurity. Pathogenesis has been well studied in human and animal disease models. Equivalent analyses of tick-flavivirus interactions are limited and represent an area of study that could reveal novel approaches for TBF control. Methodology/Principal Findings: High resolution LC-MS/MS was used to analyze the proteome of Ixodes scapularis (Lyme disease tick) embryonic ISE6 cells following infection with Langat virus …

Regulation Of Brown And White Adipocyte Transcriptome By The Transcriptional Coactivator Nt-Pgc-1Α, Jihyun Kim, Vivian E. Fernand, Tara M. Henagan, Jeho Shin, Peter Huypens, Susan Newman, Thomas W. Gettys, Ji Suk Chang

Department of Nutrition Science Faculty Publications

The β3-adrenergic receptor (AR) signaling pathway is a major component of adaptive thermogenesis in brown and white adipose tissue during cold acclimation. The β3-AR signaling highly induces the expression of transcriptional coactivator PGC-1α and its splice variant N-terminal (NT)-PGC-1α, which in turn activate the transcription program of adaptive thermogenesis by co-activating a number of transcription factors. We previously reported that NT-PGC-1α is able to increase mitochondrial number and activity in cultured brown adipocytes by promoting the expression of mitochondrial and thermogenic genes. In the present study, we performed genome-wide profiling of NT-PGC-1α-responsive genes in brown adipocytes to identify genes potentially …

Gifted Education In Rural Schools, Paige E. Yeager

Williams Honors College, Honors Research Projects

This report is a summary of the observations and data collected during twenty hours of field work and observation. This project focuses on one child, identified as gifted, in a rural school district with limited resources. The report discusses the student’s current level of performance, analysis of the developmental domains (cognitive, language, social, emotional, and motor), accommodations and modifications used by the student’s teachers, guidelines determined by the State of Ohio and the W. Local School District, alignment to the state requirements, and suggestions for the improvement of the student’s educational experience. The report will explain how the student is …

The Psychological Effects Of Cochlear Implants: A Comparison Of One Adult With A Cochlear Implant And One Without., Sarah Schwartzer

Williams Honors College, Honors Research Projects

This study involved the development, implementation and analyzation of two qualitative case studies, with one involving a profoundly deaf individual who possesses a cochlear implant, the other with an individual who possesses normal hearing ranges. Participants were given two quantitative measures of observation, the Acceptance and Action Questionnaire and the Thought Control Questionnaire, before participating in a semi-structured interview that was intended to gather information about the individuals, their life experiences, and the factors of psychological flexibility, adaptability and resiliency as applied to their lives. The semi-structured interview involved a set list of questions that were posed to the individuals; …

The Effects Of Left Vs Right Hemisphere Cerebrovascular Accident, And Treatment, Nellie M. Turner

Williams Honors College, Honors Research Projects

This project takes an in depth look at the various methods of treatment for stroke patients, the results that are gained, and the possible benefits and detriments of each type of treatment when administered properly. It examines the definition of a Cerebrovascular accident (CVA), and the various symptoms that occur when the left versus the right hemisphere is affected. The different causes of strokes are taken into account, along with the wide range of ways the victims may be affected by it, physically and mentally. It is important to be familiar with the different methods of treatment for a patient …

Economical Retrofit System To Reduce Cooking Emissions In Third World Dwellings, Jonathan Vanzummeren, Tyler Sturgeon, Ben Dalessandro

Williams Honors College, Honors Research Projects

Abstract:

The purpose of this document is to propose and demonstrate the feasibility and effectiveness of substituting an open flame biomass cooking process with a closed system with the capabilities of sustaining an adequate fire. Clay ovens or “chulhas” are the traditional piece of cooking equipment used in poorer areas of the world. They are often built inside cramped one-room housing units with little or no ventilation. The emissions released from burning fuel sources such as wood, coal, or animal waste bring with them detrimental and often fatal health problems and results in approximately 1.3 million deaths per year.

The …

Vegetative And Adaptive Traits Predict Different Outcomes For Restoration Using Hybrids, Philip A. Crystal, Nathanael I. Lichti, Keith E. Woeste, Douglass F. Jacobs

Department of Forestry & Natural Resources Faculty Publications

Hybridization has been implicated as a driver of speciation, extinction, and invasiveness, but can also provide resistant breeding stock following epidemics. However, evaluating the appropriateness of hybrids for use in restoration programs is difficult. Past the F1 generation, the proportion of a progenitor’s genome can vary widely, as can the combinations of parental genomes. Detailed genetic analysis can reveal this information, but cannot expose phenotypic alterations due to heterosis, transgressive traits, or changes in metabolism or development. In addition, because evolution is often driven by extreme individuals, decisions based on phenotypic averages of hybrid classes may have unintended results. We …

Metatranscriptome Analysis Reveals Bacterial Symbiont Contributions To Lower Termite Physiology And Potential Immune Functions., Brittany F. Peterson, Michael E. Scharf

Department of Entomology Faculty Publications

Background: Symbioses throughout the animal kingdom are known to extend physiological and ecological capabilities to hosts. Insect-microbe associations are extremely common and are often related to novel niche exploitation, fitness advantages, and even speciation events. These phenomena include expansions in host diet, detoxification of insecticides and toxins, and increased defense against pathogens. However, dissecting the contributions of individual groups of symbionts at the molecular level is often underexplored due to methodological and analytical limitations. Termites are one of the best studied systems for physiological collaborations between host and symbiota however, most work in lower termites (those with bacterial and protist …

High Resolution Genomic Scans Reveal Genetic Architecture Controlling Alcohol Preference In Bidirectionally Selected Rat Model, Chiao-Ling Lo, Amy C. Lossie, Tiebing Liang, Yunlong Liu, Xiaoling Xuei, Lawrence Lumeng, Feng C. Zhou, William M. Muir

Department of Animal Sciences Faculty Publications

Investigations on the influence of nature vs. nurture on Alcoholism (Alcohol Use Disorder) in human have yet to provide a clear view on potential genomic etiologies. To address this issue, we sequenced a replicated animal model system bidirectionally-selected for alcohol preference (AP). This model is uniquely suited to map genetic effects with high reproducibility, and resolution. The origin of the rat lines (an 8-way cross) resulted in small haplotype blocks (HB) with a corresponding high level of resolution. We sequenced DNAs from 40 samples (10 per line of each replicate) to determine allele frequencies and HB. We achieved ~46X coverage …

Case Study Of Uber Data In The Central London Area, Kaylene Widdoes

Williams Honors College, Honors Research Projects

This research project examines multi-faceted Uber data taken over a 5 week period of time (5/19/16-6/22/16) in the central London area, including wait times, exact GPS locations, days of the week analyses, and time analyses. Adapted from a 6-month work project at my company, Vertical Knowledge, this analysis explores multiple levels of depth through different visualizations of the data, from charts and graphs to an extensive Tableau analysis. Through this analysis, we were able to provide multiple explanations for anomalies in the data and provide reasoning for increased traffic and justified surge pricing during certain times and days.

Identification And Quantification Of Zooplankton In Ne Ohio Drinking Water Reservoirs, Michael Vigorito

Williams Honors College, Honors Research Projects

Cyanobacteria, or blue-green algae, are present in most freshwater ecosystems and are usually harmless. When these algae swell in numbers, they release harmful toxins that can be detrimental to animal and human health, and can destroy ecosystems. For this reason, many scientists and engineers have studied these harmful algal blooms in an attempt to predict, prevent, or control them to keep people and ecosystems safe. One of the variables in this investigation is the presence and quantity of zooplankton. These animals could play an important role in the prevalence of cyanobacteria, but more information is needed to determine what that …

Pollinator Sharing Between Mimulus Ringens And Coflowering Plant Species In Northeastern Ohio, Andrew M. Wuellner

Williams Honors College, Honors Research Projects

Competition between plants for pollinators can have serious impacts on plant reproduction; these impacts depend on many factors, such as plant abundance, plant diversity, floral abundance, pollinator abundance, and pollinator preference. The way pollinators move among and between coflowering species can tell us more about how these factors affect competition. In this study, we examine the movement patterns of flower visitors to Mimulus ringens and coflowering species in Northeastern Ohio through several types of observations. In addition, we measured the density and diversity of floral units with 20-30 meter transects across each study site. There were six total study sites, …

Review Of Fractal Heat Exchangers, Zhiwei Huang, Yunho Hwang, Vikrant Aute, Reinhard Radermacher

International Refrigeration and Air Conditioning Conference

Nature has inspired many scientists and engineers to solve problems through observation and mimicry. One such example is heat transfer enhancement. The enormous natural heat and mass transfer phenomena have led engineers to seek solutions to heat transfer enhancement problems from nature. Fractal geometries are found in respiratory and vascular systems of plants and animals, such as blood vessels, human lungs, leaves, coastlines, etc. Inspired by this, fractal heat exchangers have been developed and were found to have intrinsic advantage of minimized flow resistance and strong heat transfer capability. In current study, a comprehensive literature review was carried out to …

Stimulus Statistics Change Sounds From Near-Indiscriminable To Hyperdiscriminable, Keith Kluender R., Christian E. Stilp

Department of Speech, Language, and Hearing Sciences Faculty Publications

Objects and events in the sensory environment are generally predictable, making most of the energy impinging upon sensory transducers redundant. Given this fact, efficient sensory systems should detect, extract, and exploit predictability in order to optimize sensitivity to less predictable inputs that are, by definition, more informative. Not only are perceptual systems sensitive to changes in physical stimulus properties, but growing evidence reveals sensitivity both to relative predictability of stimuli and to co-occurrence of stimulus attributes within stimuli. Recent results revealed that auditory perception rapidly reorganizes to efficiently capture covariance among stimulus attributes. Acoustic properties per se were perceptually abandoned, …

The Importance Of Passive Sustainable Design, Caitlin Raymond

Williams Honors College, Honors Research Projects

Sustainability is a topic regularly discussed within today’s culture. Many people are worried about society’s future due to pollution, excessive use of nonrenewable resources, and more. Even with all of the growing awareness and promotion, the historical context and more specifically the passive design techniques used in buildings have received little attention. It is imperative to increase this awareness, as well as increase the application of passive sustainable techniques to ensure that sustainable building is efficient and effective. This project has two portions, a literature review and a design project. The literature review assembles research and techniques collected on passive …

Stress Corrosion Cracking Evaluation Of Carbon Steel In Biodiesel And The Effect Of Ultrasonic Nanocrystal Surface Modification (Unsm) On 304 Stainless Steel, Josh Geyer

Williams Honors College, Honors Research Projects

The project that was performed was stress corrosion cracking (SSC) of carbon steel in biodiesel, petroleum diesel and a mixture. The project also included the effect of Ultrasonic Nanocrystal Surface Modification (UNSM) on 304 stainless steel. It included the assembly of a slow strain rate (SSR) machine and carrying out testing using the SSR machine. The assembly of the machine will require purchasing and building a stand to house the electrical equipment which includes the computer, actuator control panel and the actuator power supply. The assembly will also include designing and purchasing the connections to connect the actuator to the …

Unique Behavioral And Neurochemical Effects Induced By Repeated Adolescent Consumption Of Caffeine-Mixed Alcohol In C57bl/6 Mice., Meridith T. Robins, Julie Lu, Richard M. Van Rijn

Borch Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications

The number of highly caffeinated products has increased dramatically in the past few years. Among these products, highly caffeinated energy drinks are the most heavily advertised and purchased, which has resulted in increased incidences of co-consumption of energy drinks with alcohol. Despite the growing number of adolescents and young adults reporting caffeine-mixed alcohol use, knowledge of the potential consequences associated with co-consumption has been limited to survey-based results and in-laboratory human behavioral testing. Here, we investigate the effect of repeated adolescent (post-natal days P35-61) exposure to caffeine-mixed alcohol in C57BL/6 mice on common drug-related behaviors such as locomotor sensitivity, drug …

Session 5: The Jonah Complex, Calvin University

Campus Ministries Resources

No abstract provided.

A Tomographic-Piv Investigation Of Vapor-Induced Flow Structures In Confined Jet Impingement Boiling, M. J. Rau, P. P. Vlachos, S V. Garimella

CTRC Research Publications

Tomographic particle image velocimetry (PIV) is used to study the effect of confinement gap height on the liquid flow characteristics in jet impingement boiling. This first application of tomographic PIV to flow boiling is significant given the complexity of confined two-phase jet impingement. A jet of subcooled wa- ter at a Reynolds number of 5,0 0 0 impinges onto a circular heat source undergoing boiling heat transfer at a constant heat input. Confinement gap heights of 8, 4, and 2 jet diameters are investigated. A visual hull method is used to reconstruct the time-varying regions of the vapor in the …

Experiment Design And Training Data Quality Of Inverse Model For Short-Term Building Energy Forecasting, Liang Zhang, Jin Wen, Can Cui, Xiwang Li, Teresa Wu

International High Performance Buildings Conference

For data-driven building energy forecasting modeling, the quality of training data strongly affects a model’s accuracy and cost-effectiveness. In order to obtain high-quality training data within a short time period, experiment design, active learning, or excitation is becoming increasingly important, especially for nonlinear systems such as building energy systems. Experiment design and system excitation have been widely studied and applied in fields such as robotics and automobile industry for their model development. But these methods have hardly been applied for building energy modeling. This paper presents an overall discussion on the topic of applying system excitation for developing building energy …

Ureaplasma Diversum Genome Provides New Insights About The Interaction Of The Surface Molecules Of This Bacterium With The Host, Lucas M. Marques, Izadora S. Rezende, Maysa S. Barbosa, Ana M. Guimarães, Hellen B. Martins, Guilherme B. Campos, Naila C. Do Nascimento, Andrea P. Dos Santos, Aline T. Amorim, Verena M. Santos, Sávio T. Farias, Fernanda A C Carrence, Lauro M. De Souza, Melissa Buzinhani, Victor E. Arana-Chavez, Maria E. Zenteno, Gustavo P. Amarante-Mendes, Joanne Messick, Jorge Timenetsky

Department of Comparative Pathobiology Faculty Publications

Whole genome sequencing and analyses of Ureaplasma diversum ATCC 49782 was undertaken as a step towards understanding U. diversum biology and pathogenicity. The complete genome showed 973,501 bp in a single circular chromosome, with 28.2% of G+C content. A total of 782 coding DNA sequences (CDSs), and 6 rRNA and 32 tRNA genes were predicted and annotated. The metabolic pathways are identical to other human ureaplasmas, including the production of ATP via hydrolysis of the urea. Genes related to pathogenicity, such as urease, phospholipase, hemolysin, and a Mycoplasma Ig binding protein (MIB)—Mycoplasma Ig protease (MIP) system were identified. More …

Prediction Of Air-Side Particulate Fouling Of Hvac&R Heat Exchangers, H. Inamdar, E. A. Groll, J. A. Weibel, S V. Garimella

CTRC Research Publications

Air-to-refrigerant heat exchangers used in heating, ventilation, air-conditioning, and refrigeration systems routinely experience air-side fouling due to the presence of particulates in outdoor and indoor environments. The influence on the performance of the heat exchanger, in terms of heat transfer efficiency and pressure drop imposed, depends on the extent of air-side fouling. Fouling of a heat exchanger is determined by a variety of parameters such as the dimensions of the heat exchanger, physical properties of the airborne particulates, and airflow conditions over the heat exchange surfaces. A comprehensive model is developed to deterministically calculate the extent of fouling of a …

Lección Extra 3, Calvin University

Campus Ministries Resources

No abstract provided.

Bonus Lesson On Rev 14-15, Calvin University

Campus Ministries Resources

No abstract provided.

Structural Basis For Recognition Of Human Enterovirus 71 By A Bivalent Broadly Neutralizing Monoclonal Antibody, Xiaohua Ye, Chen Fan, Zhiqiang Ku, Teng Zuo, Liangliang Kong, Chao Zhang, Jinping Shi, Qingwei Liu, Tan Chen, Yingyi Zhang, Wen Jiang, Linqi Zhang, Zhong Huang, Yao Cong

Department of Biological Sciences Faculty Publications

Enterovirus 71 (EV71) is the main pathogen responsible for hand, foot and mouth disease with severe neurological complications and even death in young children. We have recently identified a highly potent anti-EV71 neutralizing monoclonal antibody, termed D5. Here we investigated the structural basis for recognition of EV71 by the antibody D5. Four three-dimensional structures of EV71 particles in complex with IgG or Fab of D5 were reconstructed by cryo-electron microscopy (cryo-EM) single particle analysis all at subnanometer resolutions. The most critical EV71 mature virion-Fab structure was resolved to a resolution of 4.8 Å, which is rare in cryo-EM studies of …

A Review Of The Evidence Supporting The Taste Of Non‐Esterified Fatty Acids In Humans, Cordelia Running, Richard D. Mattes

Department of Food Science Faculty Publications

Dietary fats contribute to the flavor of foods by multiple mechanisms. A role for their taste has only recently gained credence. Current evidence indicates non‐esterified fatty acids (NEFA) are the effective stimuli for the taste component. CD36 and GPR120 are putative receptors, but may not fully account for the totality of the range of sensations elicited by fatty acids. The sensory quality of long‐chain NEFA is not adequately characterized by commonly accepted taste primary qualities and has been termed oleogustus. There is marked individual variability in sensitivity to the taste of NEFA prompting hypotheses of genetic and environmental determinants. Though …

Sparse Non-Negative Matrix Factorization For Mesh Segmentation, Tim Mcgraw, Jisun Kang, Donald Herring

Computer Graphics Technology Faculty Publications

We present a method for 3D mesh segmentation based on sparse non-negative matrix factorization (NMF). Image analysis techniques based on NMF have been shown to decompose images into semantically meaningful local features. Since the features and coefficients are represented in terms of non-negative values, the features contribute to the resulting images in an intuitive, additive fashion. Like spectral mesh segmentation, our method relies on the construction of an affinity matrix which depends on the geometric properties of the mesh. We show that segmentation based on the NMF is simpler to implement, and can result in more meaningful segmentation results than …

The New Eduspace Lernwerkstatt In The Library - A Collaboration Project Between The Faculty Of Education And The Library, Ulrike Stadler-Altmann, Gerda Winkler

Proceedings of the IATUL Conferences

No abstract provided.