Digital Commons Network^™

Michigan Academician, Volume 43, Issue 1

Michigan Academician

No abstract provided.

Michigan Academician, Volume 44, Issue 2

Michigan Academician

No abstract provided.

Rencontre De Partage Sur La Problématique Des Grossesses Non Désirées Chez Les Adolescents/Jeunes Au Sénégal : Compte Rendu De Rencontre, Babacar Mane, Marie-Jesus Buabey, Nafissatou Diop, Patrick Mugirwa

Reproductive Health

En 2015, la Direction de la Santé de la Reproduction et de la Survie de l’Enfant du Ministère de la Santé et de l’Action Sociale (Sénégal), le Population Council, et le bureau régional de Partners in Population and Development Africa, ont co-organisé un atelier de partage des résultats de l’étude “Comprendre les grossesses non désirées au Sénégal—Profil pays.” Ce rapport de rencontre décrit une réunion de suivi en 2016 dont les objectifs étaient d'examiner l'état de faire le point sur la mise en œuvre des recommandations de la rencontre de juin 2015; s’informer de la situation de la santé sexuelle …

Landscape Analysis Of The Family Planning Situation In Pakistan: Brief Summary Of Findings, Population Council

Reproductive Health

This brief provides a summary of the Landscape Analysis of the Family Planning Situation in Pakistan carried out by the Population Council with the support of the Bill & Melinda Gates Foundation in 2015–16. The analysis provides a comprehensive assessment of consumer demand, contraceptive service provision, and contraceptive supply, and the provincial policy environment based on primary data collection in eight districts in Punjab, Sindh, and Khyber Pakhtunkhwa. Its aim is to identify investment opportunities to catalyze an escalation in contraceptive prevalence, enabling Pakistan to meet its FP2020 goals.

Using The Community Informant-Based (Made-In And Made-For) Methodology To Estimate The Neonatal Mortality Rate (Nmr) In Nowshera, Khyber Pakhtunkhwa: A Feasibility Study, Ali M. Mir, Saleem Shaikh, Mumraiz Khan, Irfan Masood, Mansoor Qaisar, Sabahat Hussain, Rehan M. Niazi

Reproductive Health

Concerned about high levels of neonatal mortality, the Khyber Pakhtunkhwa district government in Pakistan expressed a need to adapt and test a new approach—commonly referred to as the “Made-In/Made-For” (MIMF) method—that uses community-based informants to estimate the number of maternal deaths. The current pilot study in Nowshera was commissioned by the Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ) GmbH and conducted by the Population Council to test the feasibility of using the method, and community-based informant networks that had been used to measure maternal mortality, for estimating neonatal deaths. This study clearly shows that, in addition to identifying maternal deaths, informant …

From Turkeys To Tamales: Paleoindian To Preclassic Period Faunal Use At Maya Hak Cab Pek Rockshelter In Southern Belize, Stephanie Raye Orsini

Electronic Theses and Dissertations

Very little is known about Paleoindian and Archaic subsistence strategies of the people of Mesoamerica prior to the development of ceramics. Rockshelters with good preservation and stratigraphic deposits can provide excellent contexts for a comparative faunal analysis though time. In February of 2014 the Bladen Paleoindian and Archaic Project (BPAP), directed by Dr. Keith Prufer, began excavations at the rockshelter Maya Hak Cab Pek (MHCP). The site has evidence for human activities from the Paleoindian period (11,500 BC to 8,000 BC) through the Preclassic Maya period (2,000 BC to AD 250). This research uses zooarchaeological analysis to investigate animal use …

Graduate Catalog, 2016-2017, University Of South Florida St. Petersburg. Office Of Graduate Studies

Graduate Catalogs

No abstract provided.

瑞吉欧·艾米利亚的教师研究： 一个充满活力并不断演变的角色的精髓 / Teacher Research In Reggio Emilia: Essence Of A Dynamic, Evolving Role (Chinese Translated Version)., Carolyn P. Edwards, Lella Gandini

Department of Child, Youth, and Family Studies: Faculty Publications

The Reggio Emilia approach to early childhood education has been studied for more than 50 years. Today, following the influx of new families, tighter financial situation in local government and a generational turnover of educators, there are changes seen in the role and practice of teachers, but also continuities with the past. Teachers are seen as researchers, where research is not only an attitude and approach in everyday living in and outside early childhood programs, but also a questioning attitude and inquiry process. Besides, as colleagues within a network and organization, teachers, with mutual collaboration, and observing and documenting child’s …

Urban Congolese Refugees In Kenya: The Contingencies Of Coping And Resilience In A Context Marked By Structural Vulnerability, Julie A. Tippens

Department of Child, Youth, and Family Studies: Faculty Publications

The global increase in refugee migration to urban areas creates challenges pertaining to the promotion of refugee health, broadly conceived. Despite considerable attention to trauma and forced migration, there is relatively little focus on how refugees cope with stressful situations, and on the determinants that facilitate and undermine resilience. This article examines how urban Congolese refugees in Kenya promote psychosocial well-being in the context of structural vulnerability. This article is based on interviews (N = 55) and ethnographic participant observation with Congolese refugees over a period of 8 months in Nairobi in 2014. Primary stressors related to scarcity of material …

Insertion Sites Of Feline Leukemia Virus, Alexa M. Salsbury

Senior Honors Theses and Projects

Feline Leukemia Virus (FeLV) is a transmittable RNA retrovirus that inhibits feline immune systems and predisposes its host to infections and diseases. Much is unknown about FeLV, including the nature and location of its insertion sites. Identifying insertion sites of the provirus can provide information about mechanisms of tumorigenesis and identifY new protooncogenes. To search for insertion sites, gene-specific primers were designed and a genome walking method was optimized for our application. Using the optimized process, blood and tissue samples were examined for FeLV provirus. The cat from which we received samples showed neurological symptoms before death; therefore, we hypothesized …

Cathepsin B Modulates Lysosomal Biogenesis And Host Defense Against Francisella Novicida Infection, Xiaopeng Qi, Si Ming Man, R. K. Malireddi, Rajendra Karki, Christopher Lupfer, Prajwal Gurung, Geoffrey Neale, Clifford S. Guy, Mohamed Lamkanfi, Thirumala-Devi Kanneganti

College of Natural and Applied Sciences

Lysosomal cathepsins regulate an exquisite range of biological functions, and their deregulation is associated with inflammatory, metabolic, and degenerative diseases in humans. In this study, we identified a key cell-intrinsic role for cathepsin B as a negative feedback regulator of lysosomal biogenesis and autophagy. Mice and macrophages lacking cathepsin B activity had increased resistance to the cytosolic bacterial pathogen Francisella novicida. Genetic deletion or pharmacological inhibition of cathepsin B down-regulated mechanistic target of rapamycin activity and prevented cleavage of the lysosomal calcium channel TRPML1. These events drove transcription of lysosomal and autophagy genes via transcription factor EB, which increased lysosomal …

Lynnsight: Winter 2016, Lynn University

(2004-2021) LynnSight(s)

Winter 2016 LynnSight:

• Christine E. Lynn gives largest gift in university history
• Lynn dedicates Perper field
• Circle of flags named in honor of Yvonne S. Boice

Planimetry Investigation Of The Corpus Callosum In Temporal Lobe Epilepsy Patients, Veli Caglar, Selen I. Alp, Berrin T. Demir, Umit Sener, Oguz A. Ozen, Recep Alp

Neurosciences

Objective: To evaluate the effects of temporal lobe epilepsy (TLE) on corpus callosum (CC) morphometry in patients with TLE. Methods: This retrospective study was conducted at the Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey between November 2010 and December 2013. The epileptic syndrome diagnosis was based on International League Against Epilepsy criteria, and this study was conducted on the MRIs of 25 epilepsy patients and 25 control subjects. We classified the patients according to their duration of epilepsy <10 and ≥10 years. The projection area length (PAL) of the CC was also estimated. Total brain volumes (TBV) were measured on CT images. Results: The mean values of TBV for patients with TLE and the control group were not statistically different, but the CC PAL values were statistically different. The mean CC PAL values of under and over 25 years of age in patients with TLE were statistically different. The mean values of TBV of under and over 10 years duration of TLE were small statistically, but the CC PAL values were statistically different. Conclusion: The results indicate a clear influence of TLE on the structure of the CC rather than TBV.

The Use Of Immune Modulating Drugs For The Treatment Of Multiple Sclerosis, Fahd A. Al-Khamis

Neurosciences

This review discusses the mechanisms of action of 4 immune modulating drugs currently used in the treatment of multiple sclerosis (MS), including Alemtuzumab, a humanized monoclonal antibody that functions by targeting CD52, an antigen primarily expressed on T and B lymphocytes and monocytes/macrophages, resulting in their depletion and subsequent repopulation; Dimethyl fumarate that switches cytokine production toward a T helper 2 profile and enhances cytosolic levels of nuclear factor erythroid 2–related factor 2, which has immune regulatory and cytoprotective effects on oligodendrocytes, neurons, and glial cells; Fingolimod functions by blocking the release of activated lymphocytes from lymph nodes by targeting …

Incidence Of Autism In High Risk Neonatal Follow Up, Hussein S. Mohammed, Saeed H. Wahass, Adel A. Mahmoud

Neurosciences

Objective: To detect autism spectrum disorder (ASD) cases within the High Risk Neonatal Follow up Program (HRNFP), as an indicator of the prevalence of ASD and associated risk factors in the Kingdom of Saudi Arabia (KSA). Methods: We conducted this retrospective medical chart review in a tertiary care hospital in Riyadh, KSA. All patients admitted to the HRNFP were seen at 3 years corrected age between January 2012 and December 2013. Patients diagnosed with ASD from the HRNFP were referred to the King Fahad Medical City (KFMC) Autism Program for further assessment. The following potential risk factors for ASD were …

Serum Levels Of Zinc And Copper In Epileptic Children During Long-Term Therapy With Anticonvulsants, Mahmood D. Al-Mendalawi

Neurosciences

No abstract provided.

Walk Like Me, Talk Like Me: The Connection Between Mirror Neurons And Autism Spectrum Disorder, Jillian M. Saffin, Hassaan Tohid

Neurosciences

Understanding social cognition has become a hallmark in deciphering autism spectrum disorder. Neurobiological theories are taking precedence in causation studies as researchers look to abnormalities in brain development as the cause of deficits in social behavior, cognitive processes, and language. Following their discovery in the 1990s, mirror neurons have become a dominant theory for that the mirror neuron system may play a critical role in the pathophysiology of various symptoms of autism. Over the decades, the theory has evolved from the suggestion of a broken mirror neuron system to impairments in mirror neuron circuitry. The mirror neuron system has not …

Effects Of Thymoquinone, The Major Constituent Of Nigella Sativa Seeds, On Penicillin-Induced Epileptiform Activity In Rats, Ersin Beyazcicek, Seyit Ankarali, Ozge Beyazcicek, Handan Ankarali, Serif Demir, Recep Ozmerdivenli

Neurosciences

Objective: To investigate the effects of thymoquinone (TQ) in a penicillin-induced epilepsy model in rats. Methods: This experimental study included 56 adult male Wistar rats. Experiments were performed in the Research Laboratory of the Department of Physiology, Medical School, Duzce University, Duzce, Turkey, between October 2013 and December 2014. Animals were divided into the following 7 groups: sham, control, only thymoquinone, vehicle (Dimethylsulfoxide), and doses of 10, 50, and 100 mg/kg of TQ. After rats were anesthetized, the left part of the skull was removed. A pair of silver/silver chloride electrodes was placed on the somatomotor area, and electrocorticographic recording …

The 5th Annual Saudi Epilepsy Society Conference, 1st Gcc Epilepsy Conference, 2nd Joined Emirate Saudi Epilepsy Conference, 8th Annual Eastern Province Epilepsy Conference, 14th Annual Saudi Chapter Of Epilepsy Conference7-9th November 2015, Dammam, Saudi Arabia,Meeting Highlights: Treatment And Prognosis Of Symptomatic Generalized Epilepsyintegration Of New Antiepileptic Drugs Into Clinical Practiceare Seizure Medicine So Bad?Are Neonatal Seizures So Bad?Dense Array Eeg And Eeg Source Localization In Clinical Practicethe Role Of Marijuana In The Treatment Of Epilepsydebate: A) Should We Treat Anoxic/Myoclonic Seizures?B) Post Anoxic Seizuresdriving And Epilepsy In Diagnosed Patients Attending King Fahad Specialist Hospital In Dammam, Eastern Province Of Saudi Arabiadepression In Epileptic Patients Is Influenced By The Duration Of Epilepsy. A Cross Sectional Study Involving Patients With Epilepsy In Southern Saudi Arabiais Parental Consanguinity A Risk Factor For Epilepsy? A Cases-Control Study Assessing Epilepsy Risks In Southern Saudi Arabiaprevalence Of Epilepsy Stigma In Riyadh, Saudi Arabiathe Hazy Temporal Neocortex Sign On Magnetic Resonance Imaging. Clinical Significance In Temporal Lobe Epilepsy, Raidah S. Al-Baradie

Neurosciences

The 5th Annual Saudi Epilepsy Society Conference, and the 1st GCC Epilepsy Conference was held in Le-Meridian Hotel, Al Khobar, Kingdom of Saudi Arabia on 7th-9th November, 2015 organized by Saudi Epilepsy Society in collaboration with the Department of Pediatric Neurology, Neuroscience Center, King Fahd Specialist Hospital, Dammam, Saudi Arabia. The scientific program was loaded with innovative and interactive presentations from respected and reputable speakers from different parts of the world. Abstracts were carefully selected and reviewed based on their scientific value and relevance to the clinical, surgical, academic, and research aspects of epilepsy in the Saudi Arabia, and the …

Evidence-Based Neurosurgery: Basic Concepts For The Appraisal And Application Of Scientific Information To Patient Care (Part Ii), Ignatius N. Esene, Saleh S. Baeesa, Ahmed Ammar

Neurosciences

Medical evidence is obtainable from approaches, which might be descriptive, analytic and integrative and ranked into levels of evidence, graded according to quality and summarized into strengths of recommendation. Sources of evidence range from expert opinions through well-randomized control trials to meta-analyses. The conscientious, explicit, and judicious use of current best evidence in making decisions related to the care of individual patients defines the concept of evidence-based neurosurgery (EBN). We reviewed reference books of clinical epidemiology, evidence-based practice and other previously related articles addressing principles of evidence-based practice in neurosurgery. Based on existing theories and models and our cumulative years …

Risk Factors And Subtypes Of Acute Ischemic Stroke: A Study At King Fahd Hospital Of The University, Azra Zafar, Fahd A. Al-Khamis, Aishah I. Al-Bakr, Abdulla A. Alsulaiman, Amir H. Msmar

Neurosciences

Objective: To identify the different subtypes of acute ischemic stroke, and estimate the frequency of various risk factors among these patients. Methods: In this retrospective, cross-sectional study, we reviewed the medical records of patients admitted with the diagnosis of acute ischemic stroke at King Fahd Hospital of the University, Al-Khobar, Saudi Arabia from March 2008 till December 2015. The demographic characteristics, subtypes of stroke, risk factors (hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, atrial fibrillation, valvular heart disease) and other relevant data were documented on pre-defined data sheets. Results: The records of 343 patients were included in the study; 64.4% …

Cerebral Fat Embolism Syndrome Following Total Knee Replacement Causing A Devastating Neurocognitive Sequelae, Dareen S. Al-Shaer, Omar Ayoub, Naushad A. Ahamed, Amro M. Al-Hibshi, Saleh S. Baeesa

Neurosciences

No abstract provided.

A Diagnostic Riddle In An Immunocompetent Adult: Meningioma Or Intracranial Fungal Granuloma?, Syed A. Ali, Anita Jagetia, Kavita Gaur, Puja Sakhuja

Neurosciences

No abstract provided.

Longwood University Catalog 2016-2017, Longwood University

Undergraduate Catalogs

No abstract provided.

Tennessee Ag Insider, A Guide The The State's Farms, Food, And Forestry, 2016 Edition, Tennessee. Department Of Agriculture.

Tennessee Ag Insider

No abstract provided.

Appearance Of Membrane Compromised, Viable But Not Culturable And Culturable Rhizobial Cells As A Consequence Of Desiccation, Jan A.C. Vriezen, Frans J. De Bruijn

Biological Sciences: Faculty Publications

For agricultural purposes, drought related stresses negatively affect the Rhizobiaceae in at least three ways. Firstly, rhizobial populations are affected by desertification of agricultural soils. Secondly, the quality of dry-base inocula, also called formula, is negatively affected by a drying step, and thirdly, rhizosphere bacteria protect crop-plants against drought. Although survival of cultivatable bacteria has been studied intensively in dry-base seed inocula and in-vitro, thus far research has only marginally addressed the bacterial cell, its cellular structures and physiology. Many questions remain regarding the sensing of and physiological response of rhizobia to desiccation. This review will focus on the three …

Groundwater Report 305b 2016, Tennessee. Department Of Environment And Conservation.

Groundwater Assessment

No abstract provided.

The Armstrong Evolution, Michael Pappas

Publications

No abstract provided.

Restoration Of Intrinsic Inhibition In The Pfc To Prevent Relapse To Cocaine Seeking, William C. Buchta

MUSC Theses and Dissertations

Reward learning involves burst firing of midbrain dopamine neurons in the Ventral Tegmental Area (VTA). The resulting dopamine release from VTA terminals instructs regions like the prefrontal cortex (PFC) about rewards and reward-related cues. Glutamatergic PFC neurons initiate motivated behaviors via innervation of the nucleus accumbens. Chronic use of drugs of abuse such as cocaine disrupts this natural reward pathway, leading to enduring cellular adaptations in dopaminergic signaling that contribute to relapse vulnerability. However, how dopamine modulates activity in this circuitry is not known. We posit that dopamine release from VTA terminals gates intrinsic inhibition in the PFC via a …

Mechanisms Of Subtype-Specific Inhibition Of N-Methyl-D-Aspartate Receptors By Ethanol, Benjamin A. Hughes

MUSC Theses and Dissertations

Alcoholism is a debilitating and costly disease with rates of prevalence totaling nearly 6% worldwide. Treating this disease has proven expensive and in many cases ineffective due in large part to significant gaps in our knowledge of the molecular determinants that drive the pathogenesis of the disorder. Recently, the N-methyl-D-aspartate (NMDA) receptor has emerged as a candidate site for the primary inhibitory actions of ethanol on nervous system function. This receptor is an ion channel highly expressed in the nervous system that is activated by the excitatory neurotransmitter glutamate and has been implicated in the induction of a number of …