Digital Commons Network^™

Predicting Dna Methylation State Of Cpg Dinucleotide Using Genome Topological Features And Deep Networks, Yiheng Wang, Tong Liu, Dong Xu, Huidong Shi, Chaoyang Zhang, Yin-Yuan Mo, Zheng Wang

Faculty Publications

The hypo- or hyper-methylation of the human genome is one of the epigenetic features of leukemia. However, experimental approaches have only determined the methylation state of a small portion of the human genome. We developed deep learning based (stacked denoising autoencoders, or SdAs) software named "DeepMethyl" to predict the methylation state of DNA CpG dinucleotides using features inferred from three-dimensional genome topology (based on Hi-C) and DNA sequence patterns. We used the experimental data from immortalised myelogenous leukemia (K562) and healthy lymphoblastoid (GM12878) cell lines to train the learning models and assess prediction performance. We have tested various SdA architectures …

Do Vertebral Chemical Signatures Distinguish Juvenile Blacktip Shark (Carcharhinus Limbatus) Nursery Regions In The Northern Gulf Of Mexico?, Justin P. Lewis, William F. Patterson Iii, John K. Carlson, Katherine Mclachlin

Faculty Publications

Identifying and protecting shark nurseries is a common management strategy used to help rebuild overfished stocks, yet we know little about connectivity between juvenile and adult populations. By analysing trace metals incorporated into vertebral cartilage, it may be possible to infer natal origin based on nursery-specific chemical signatures. To assess the efficacy of this approach, we collected juvenile blacktip sharks (Carcharhinus limbatus; n = 93) from four regions in the Gulf of Mexico in 2012 and 2013 and analysed their vertebral centra with laser ablation-inductively coupled plasma-mass spectrometry. We observed significant regional differences in six element : Ca …

#Iftheygunnedmedown: Postmodern Media Criticism In A Post-Racial World, Christopher P. Campbell

Faculty Publications

After the 2014 fatal shooting of Michael Brown, an unarmed 18-year-old African American man, by a White police officer in Ferguson, Missouri, some news organizations included in their immediate coverage a photo of Brown taken from his Facebook page. In a now iconic image, Brown stands in a Nike tank top, unsmiling, and flashing a peace sign (misidentified by some news organizations as a gang sign). Later, less incendiary photos from Brown’s Facebook page surfaced. Within a few days of Brown’s death, the hashtag #IfTheyGunnedMeDown appeared on social media. Young African Americans posted two photos of themselves, representing positive and …

Bridge Over Troubled Waters: Resolving The Ri Grande (Rio Bravo) Water Dispute., Ruben R. Barrera, Dan A. Naranjo

St. Mary's Law Journal

Abstract Forthcoming.

The Admissibility Of Aerial Photographs - Evidentiary Foundations., Kristopher R. Hufstetler

St. Mary's Law Journal

Services such as Google Maps and MapQuest significantly impact how consumers use the Internet. For as much as they contribute to Internet use, issues arise concerning the use of satellite images and aerial photographs in the context of litigation. Historical concerns about satellite and aerial imagery typically involved expectations of privacy and the application of the Fourth Amendment. Courts and citizens alike express concern with when and where privacy ends with respect to aerial views. Concerns as to the admissibility of aerial photographs have also been prominent. Specifically, interest in admissibility of these photographs focuses on sufficiency, relevance, and accuracy. …

The Development Of Chinese Constitutionalism, Chenglin Liu

St. Mary's Law Journal

Since the establishment of the People's Republic of China (PRC) in 1949, the country has enacted four constitutions. This Article provides a historical analysis of how the Communist Party of China (the Party) and its paramount leaders shaped each constitution, influenced the public perception of the law, and determined the method individual constitutional rights should be permitted. Through examining leading incidents that defined the PRC's history, this Article provides a detailed examination of how the Party used a constitutional framework to achieve its specific agenda of the time.

Animism Among Western Buddhists, Daniel S. Capper

Faculty Publications

Myriad instances of animist phenomena abound in the Buddhist world, but due to the outdated concepts of thinkers such as Edward Tylor, James George Frazer, and Melford Spiro, commonly scholars perceive this animism merely as the work of local religions, not as deriving from Buddhism itself. However, when one follows a number of contemporary scholars and employs a new, relational concept of animism that is based on respectful recognition of nonhuman personhoods, a different picture emerges. The works of Western Buddhists such as Stephanie Kaza, Philip Kapleau Roshi, and Gary Snyder express powerful senses of relational animism that arise specifically …

The Maternal Personhood Of Cattle And Plants At A Hindu Center In The United States, Daniel S. Capper

Faculty Publications

Religious experiences with sacred nonhuman natural beings considered to be “persons” remain only vaguely understood. This essay provides a measure of clarification by engendering a dialogue between psychoanalytic self psychology on one side and, on the other, religious experiences of cattle and Tulsi plants as holy mothers at a Hindu cattle sanctuary in the United States. Ethnographic data from the Hindu center uncover experiences of sacred maternal natural beings that are tensive, liminal, and colored with affective themes of nurturance, respect, and intimacy, much like psychoanalytic maternal selfobjects. Devotees protect cattle and ritually venerate plants because these actions facilitate a …

Groundhog Oracles And Their Forebears, Daniel S. Capper

Faculty Publications

Groundhog Day animal weather forecasting ceremonies continue to proliferate around the United States despite a lack of public confidence in the oracles. This essay probes religio-historical and original ethnographic perspectives to offer a psychological argument for why these ceremonies exist. Employing Paul Shepard’s notion of a felt loss of sacred, intimate relationships with nonhuman nature, as well as Peter Homans’ concept of the monument that enables mourning, this essay argues that groundhog oracles serve as monuments that allow humans experientially to attempt to heal lost sacred relationships with animals like weather forecasting bears, hedgehogs, and badgers

Public Participation In Risk Regulation: The Flaws Of Formality, Emily Hammond

Utah Law Review

Dread risks draw significant public attention in both the administrative process and the courts. Yet there are a number of dysfunctions at the intersection of procedures, participation, and agency decision-making regarding such risks. This Article elaborates the participatory dysfunctions for dread risk regulation, considering formal APA procedures as well as casting complexity as a variety of formality. Inspired by recent executive actions for improving participation and incorporating social science insights into the regulatory process, this Article sets a research agenda that spans the fields of risk perception, procedural justice, and administrative law.

Mediation As Regulation: Expanding State Governance Over Private Disputes, Lydia Nussbaum

Utah Law Review

Across the United States, state legislatures are issuing new mediation mandates that govern how private parties resolve their disputes. Legislatures embed these mediation mandates into specific statutory regimes ranging from foreclosure to health care to insurance coverage. Rather than leave decisions about ADR design to other state institutions, like courts or administrative agencies, legislatures increasingly retain that authority and formalize the mediation process with legal requirements that regulate parties’ behavior and influence mediation outcomes. This Article explains how legislatures wield mediation as a regulatory tool in this latest phase of mediation’s institutionalization. It argues that statutory mediation mandates should be …

From Rights To Dignity: Drawing Lessons From Aid In Dying And Reproductive Rights, Yvonne Lindgren

Utah Law Review

The transformation of AID from a constitutional rights frame to a healthcare frame highlights the importance of developing a healthcare model related to dignity that isundergirded by social support, legal rights and healthcare access. However, the history of the abortion right cautions against narrowly identifying healthcare within the confines of the individual doctor-patient relationship because it risks subordinating the decisional autonomy of patients to the decision-making of their doctors. Taken together, these movements gesture toward situating rights within a healthcare framing that considers how social, political and economic systems and relationships come to bear upon decision-making. I conclude that while …

Combined Effects Of Ocean Acidification, Ocean Warming And Oil Spill On Aspects Of Development Of Marine Invertebrates, Maj Arnberg

School of Biological and Marine Sciences Theses

For decades, humans have impacted marine ecosystems in a variety of ways including contamination by pollution, fishing, and physical destruction of habitats. Global change has, and will, lead to alterations in in a number of abiotic factors of our ocean in particular reduced oxygen saturation, salinity changes, elevated temperature (ocean warming or OW) and elevated carbon dioxide (ocean acidification or OA). Now and in the future, OA and OW will operate together with local anthropogenic drivers such as oil pollution. And yet, at present, very little is known about their potential combined interactive effects on physiological performance and tolerance of …

Smoke 'Em If You Got 'Em: Intellectual Property Rights In The Tobacco Industry Going Up In Smoke, Kristen Lease

Case Western Reserve Journal of International Law

The Tobacco Plain Packaging Act (TPPA) was passed in Australia in 2011 and set restrictions on the appearance of tobacco packages. The restrictions limited the use of trademarks to only the brand name, and banned any use of distinctive colors or images. Tobacco growing nations believed this restriction on trade dress violated Article 20 of the Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement, which guarantees that no restriction may unjustifiably encumber intellectual property. Article 8 of the TRIPS Agreement, however, allows for encumbrances when it is intended to promote the protection of public health and safety. The tobacco growing …

Fogging Practices Of Iowa Counties For Mosquito Abatement, Alex Jay Davey

Graduate Research Papers

Global warming has been associated with an increase of mosquito-borne diseases. Mosquito-borne diseases currently have no prescription remedies. The counties across the state of Iowa will increase their fogging procedure, to supplement the increase in mosquitos and mosquito-borne diseases. This study examined which chemicals each county uses for mosquito abatement, the patterns and frequency of spraying, and what patterns of human exposure may be occurring. The county auditor was identified and recruited via email. The county auditors across the state forwarded the email message to the Environmental Health Director, in each county. At county level, they are not in control …

Self-Study Of One To One Reading Conferences In A Third Grade Setting, Angel Munson

Graduate Research Papers

This paper is a study of my teaching while conducting one to one reading conferences in a third grade classroom. The reading conference consists of the teacher and student meeting to discuss the text the student is currently reading. After engaging m discussion, usually prompted by the teacher, the teacher shares a teaching point with the student. The student is then asked to focus on this teaching point during independent reading. The paper focuses on discovering how the teacher makes instructional decisions during these one to one conferences. Data sources include conference notes, audio recorded sessions between the literacy coach …

The Effect Of Serious Gaming On Elementary Student Learning, Amanda Moritz

Graduate Research Papers

With our ever-changing technological world, schools need to incorporate more engaging learning activities that expose and extend students' learning with technologies. This literature review investigated the effects of serious gaming activities on student achievement. Thirty peer-reviewed journals were selected, analyzed, and evaluated. These studies were conducted about a variety of subject areas in the elementary setting in different areas around the world. Research evidence suggested that serious gaming, whose primary goal is not entertainment but instead to educate the user, can improve student achievement, meet their different learning styles, and enhance student motivation across curricular areas and regions. Recommendations for …

The Impact Of Specific Interventions On Child Engagement In A Preschool Classroom, Sarah Elizabeth Farber

Graduate Research Papers

The purpose of my action research was to integrate environmental changes and instructional strategies into my preschool classroom. These strategies were presented at monthly professional development trainings, which focused on increasing the engagement of all students in the classroom. This study included a sample of three students, two general education students and one with an individualized education program (IEP). These students were video recorded once a month at group time and observed using a data collection tool presented at the professional development meetings.

The results showed that the environmental changes and instructional strategics implemented were effective in increasing the engagement …

Eleanor Burts Collection - Accession 845, Eleanor Norris Burts

Manuscript Collection

The Eleanor Burts Collection consists of children themed books, artifacts, artwork, posters, puzzles, and other miscellaneous items that were collected by Eleanor Norris Burts (1916-1998) throughout her life. Eleanor Burts was a 1937 graduate of Winthrop College and lifelong educator. She was an avid collector of artifacts, artwork, and mainly books related to children and amassed a very large collection of materials that date back to the 1700s.

Polychlorinated Biphenyl Compound And Metal Contamination And Remediation In Torch Lake, Houghton County, Mi, Ankita Mandelia

Dissertations, Master's Theses and Master's Reports

Torch Lake was subject to approximately 100 years of industrial pollution due to the dumping of waste associated with copper mining in the Keweenaw Peninsula, which lasted from approximately the 1860s through the 1960s. It is well-known that this waste included copper-containing mine tailings. What was less understood are the impacts of polychlorinated biphenyls (PCBs) and heavy metals besides copper on the lake system.

The objectives of this thesis are to summarize the status of contamination and remediation activities in Torch Lake and to estimate the magnitude of potential sources of PCBs to Torch Lake. First, a brief overview of …

A Wireless Sensor System With Digitally Controlled Signal Conditioning Circuit For Force Monitoring At Bone Fixation Plates, Govindan Suresh

Dissertations, Master's Theses and Master's Reports

Post-rehabilitation of orthopedic surgery is critical for bone fracture treatments. Current protocols are not based on quantitative assessments of the patient condition but they are conservative estimations mostly based on prior experience and physician’s opinions. While there are quantitative methods for assessing the recovery of orthopedic surgery, they are typically very expensive and provide only snapshots during the healing process. A standalone, reconfigurable, embedded wireless sensor system with digitally controlled signal conditioning system capable of providing continuous monitoring of bone healing is developed. Strain sensor measurements were validated against a commercial mechanical loading instrument for relevant loads that an animal …

Salt Sensitive Hypertension And Orexin, Mike Huber

Dissertations, Master's Theses and Master's Reports

Elevated plasma arginine vasopressin (AVP) levels have been found in human hypertension subjects and several salt dependent experimental animal models of hypertension including the Dahl salt sensitive hypertension (SSHTN) model. The orexin system is involved in AVP regulation and its over activation has been implicated in hypertension, however, the role of brain orexin in SSHTN is unknown. We hypothesized that increased activity of orexin in the paraventricular nucleus (PVN), a prominent region in AVP production, contributes to SSHTN via enhancing AVP signaling. Eight-week-old male adult Dahl salt sensitive (DS) and age and sex matched Sprague Dawley (SD) rats were placed …

Carbon Flux Dynamics In High Altitude Peatlands In The Ecuadorian Andes, Maria Elisa Sanchez Garces

Dissertations, Master's Theses and Master's Reports

Although knowledge of peatland CH₄ and CO₂ exchange in temperate mountain ecosystems is available, information about carbon (C) exchange in peatlands of the Andean mountains is limited and these ecosystems may behave differently given the particular characteristics of the Andean tropics. These ecosystems are highly productive and under pressure by grazing. Our first objective was to measure baseline carbon dioxide (CO₂) and methane (CH₄) flux in an undisturbed peatland in Cayambe-Coca National Park. Our second objective was to quantify CO₂ and CH₄ fluxes in an intensively cattle grazed peatland near Antisana Ecological …

Activity Level As A Moderator Of The Relationship Between Child And Maternal Anxiety, Paige Marie Ryan

LSU Master's Theses

Anxiety is excessive and impairing for approximately 30% of individuals. Families with anxiety problems tend to pass on those problems to their children, specifically due to a variety of factors: genetics, parenting style, and other environmental risks. On the other hand, promoting behaviors like positive activity scheduling, participation in clubs, and physical activity has been shown to decrease symptoms of anxiety. However, research has yet to focus on this relationship by increasing activity level (e.g., participation in organizations, hobbies, sports). The purpose of this study is to investigate if the relationship between maternal and child anxiety is dependent upon the …

Influence Of Fertilizer Source And Irrigation Regimen On Containerized Production Of Coleus (Plectranthus Scutellarioides (L.) Codd) 'Solar Sunrise' And Management Of Bermudagrass (Cynodon Dactylon (L.) Pers. X C. Transvaalensis Burtt-Davy) 'Tifway', Kayla Renee Sanders

LSU Master's Theses

Fertilizer nutrient losses through leachate and runoff from excessive irrigation in nursery container production and turfgrass management can be high and have negative environmental impacts. The objective of this research was to examine the influence of fertilizer source and irrigation regimen on nutrient losses during nursery container production and turfgrass management. During the container production of coleus (Plectranthus scutellarioides (L.) Codd) 'Solar Sunrise', four fertilizer treatments: an unfertilized control; a controlled-release (CRF); a water-soluble (WSF); and a combination of 10% WSF and 90% CRF, were incorporated into a pine bark substrate at 0.30 kg N and P·m-3 in 3.7-L containers …

Early Copper Smelting In The Lake Superior Region:A Case Study Of The Isle Royale And Ohio Mining Company, 1846-1852, Adrian Blake

Dissertations, Master's Theses and Master's Reports

The lodes of native copper found in the Lake Superior region presented new opportunities for investors and miners alike. Making these opportunities pay required the unique challenges presented by the region’s remoteness and unique geological formations to be overcome. A primary way in which these newly emerging companies overcame these challenges was through successful vertical integration of the copper refining industries. Smelting came to the region early, but met with little success as the workers first needed to retool their skills and experiences to the demands of the region’s mineral deposits. In 1848 the Isle Royale and Ohio Mining Company …

A Nocsae Drop Test/ 3d-Fem Study On The Relationship Between Kinematic Response Of The Head, Head Impact Contact Pressure (Hicp) And Kinetic Response Of The Brain To Delineate The Risk Of Traumatic Brain Injuries (Tbi)., Raghavendra Krishna Tej Bhamidipati

Dissertations, Master's Theses and Master's Reports

How many times have you seen a person slip and fall down and had a good laugh about it? How many times we slip and fall down on the floor and got up and walked away thinking everything is normal? Probably we might wonder “Are drops which occur at a small height dangerous?” Yes, they can be. Brain injuries are main reason for the fatality in youth [1], and low level falls are one of the most neglected and understated injuries.

The main objective of this study is to study the response of the brain for low level falls from …

A Characterization Of The Water Quality Conditions And Pollutant Loads In Surface Waters Near The Northeast Ohio Regional Sewer District’S Combined Sewer System In Cleveland, Ohio, Nathan Zgnilec

Dissertations, Master's Theses and Master's Reports

The Northeast Ohio Regional Sewer District (NEORSD, Cleveland, OH) serves over one million citizens through the operation of three waste water treatment plants. NEORSD provides this service through combined and separated sewer systems, which, during rainfall events, are known to deliver large volumes of untreated wastewater containing high concentrations of Escherichia coli (E.coli), ammonia nitrogen, and phosphorus. NEORSD is currently investing $3 billion over the next 25 years to mitigate its combined sewer overflows and plans to allocate additional funds to improve remaining pollutant sources related to its system, e.g. separated sewers. A suite of PC-SWMM pollutant loading models have …

Effect Of Disulfide Bond Scrambling On Protein Stability, Aggregation, And Cytotoxicity, Colina Dutta

Dissertations, Master's Theses and Master's Reports

Proteins are nano-machines that carry out majority of the cellular functions. Thermodynamically they are functional and stable within a very narrow range (1 kcal/mol). External perturbations in the form of pH change, thermal, or oxidative/reducing stress can destabilize the protein resulting in misfolding and aggregation. Prolonged environmental stress can affect the cells adaptive response resulting in loss of ability to refold or recycle proteins. This can lead to accumulation of misfolded or aggregated proteins within the cell. Such accumulation of aggregated proteins have been associated with neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS), Parkinson’s, Huntington’s, and Alzheimer’s disease. There …

Archaeological Investigations And Historical Survey, Fort Wilkins Historic State Park: Keweenaw County, Michigan, Eric T. Pomber

Dissertations, Master's Theses and Master's Reports

Michigan Technological University has been performing archaeological and historical surveys at Fort Wilkins Historic State Park as part of a multi-year contract since 2013 with each year’s work focused on different properties held by the Park. The 2015 field season focused on the 6 acre Copper Harbor Range Lighthouse (20KE33) property immediately west of Fanny Hooe Creek resulting in the identification of eight archaeological features through a combination of pedestrian survey, shovel pit testing, and excavation. Among the features identified are the Astor House (20KE83), an early hotel in the region which was noted in the writings of travelers visiting …