Digital Commons Network^™

Role Of B Cell Receptor Signaling In Il-10 Production By Normal And Malignant B-1 Cells., Sara S Alhakeem, Vishal J Sindhava, Mary K Mckenna, Beth W Gachuki, John C Byrd, Natarajan Muthusamy, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

B-1 cells are considered innate immune cells, which produce the majority of natural antibodies. B-1 cell responses to B cell receptor (BCR) and Toll-like receptor ligation are tightly regulated owing to the cross-reactivity to self-antigens. CD5 has been shown to play a major role in downregulation of BCR responses in B-1 cells. Here, we provide evidence for another mechanism by which BCR response is regulated in B-1 cells. B-1 cells, as well as their malignant counterpart, B cell chronic lymphocytic leukemia (B-CLL) cells, produce interleukin-10 (IL-10) constitutively. IL-10 secretion by normal B-1 cells downregulates their proliferation responses to BCR ligation. …

Domestic Relations, Barry B. Mcgough, Elinor H. Hitt, Katherine S. Cornwell

Mercer Law Review

This Article addresses significant case law that arose during the survey period,' minor statutory changes specific to child support, and changes to the Uniform Superior Court Rules.

Labor And Employment Law, W. Melvin Haas Iii, William M. Clifton Iii, W. Jonathan Martin Ii, Alyssa K. Peters

Mercer Law Review

No abstract provided.

Victim Compensation Funds And Tort Litigation Following Incidents Of Mass Violence, Paul Heaton, Ivan Waggoner, Jamie Morikawa

Buffalo Law Review

No abstract provided.

The Daily Gamecock, Tuesday, December 1, 2015, The University Of South Carolina, Office Of Student Media

December

No abstract provided.

An Epigenetic Toolkit Allows For Diverse Genome Architectures In Eukaryotes, Xyrus X. Maurer-Alcalá, Laura A. Katz

Biological Sciences: Faculty Publications

Genome architecture varies considerably among eukaryotes in terms of both size and structure (e.g. distribution of sequences within the genome, elimination of DNA during formation of somatic nuclei). The diversity in eukaryotic genome architectures and the dynamic processes are only possible due to the well-developed epigenetic toolkit, which probably existed in the Last Eukaryotic Common Ancestor (LECA). This toolkit may have arisen as a means of navigating the genomic conflict that arose from the expansion of transposable elements within the ancestral eukaryotic genome. This toolkit has been coopted to support the dynamic nature of genomes in lineages across the eukaryotic …

Legacy - December 2015, South Carolina Institute Of Archaeology And Anthropology--University Of South Carolina

SCIAA Magazine - Legacy & PastWatch

Contents:

UofSC Archaeologists Raise Trio of Civil War Cannons.....p. 1
Archaeologists Pluck 3 Civil War Cannons from River Site.....p. 1
Director's Notes.....p. 2
Arkhaios Cultural Heritage and Archaeology Film Festival.....p. 2
Recovery of CSS Pee Dee Armament from the Great Pee Dee River.....p. 4
Parris Island Canoe and Exhibit Reconstruction.....p. 10
In Search of Yamasee Indian Villages in Upper Port Royal Waters.....p. 12
Chicasa: Searching for de Soto in Mississippi, June 2015.....p. 15
Fort Motte Research-2015 Update.....p. 18
Trench Maps: Military Cartography on the Western Front, 1914-1918.....p. 21
Santa Elena Foundation Opens History Center.....p. 22
Early Archaic Settlement Along the …

In Search Of Yamasee Indian Villages In Upper Port Royal Waters, James D. Spirek, Chester B. Depratter

Faculty & Staff Publications

No abstract provided.

Early Archaic Settlement Along The Central Savannah River, Re-Visited, J. Christopher Gillam

Faculty & Staff Publications

No abstract provided.

Arrested Development In Search Law: A Look At Disputed Consent Through The Lens Of Trespass Law In A Post-Jones Fourth Amendment - Have We Arrived At Disputed Analysis?, J. Bryan Boyd

Seton Hall Law Review

No abstract provided.

Major Theft In The Major Leagues: Application Of The Flsa Seasonal Employer Exemption To Professional Sports, Kristin Spallanzani

Seton Hall Law Review

No abstract provided.

Table Of Contents - Vol. 46, No. 1 2015

Seton Hall Law Review

No abstract provided.

The Comprehensive Capital Analysis And Review And The New Contingency Of Bank Dividends, Robert F. Weber

Seton Hall Law Review

No abstract provided.

The Child Support "Tax" : Determining The Effect Of Child Support On The Income Growth Of Noncustodial Parents, Jesse Snook

Theses and Dissertations

This study examines the role of child support in determining income growth. Using an Ordinary Least Squares (OLS) model with state-level fixed effects applied to panel data from the National Study of Families and Households (NSFH), I find that having a legal agreement to pay child support has a significant and negative effect on the income growth of the noncustodial parent. Specifically, after controlling for demographic variables and the respondent’s economic circumstances in the initial time period, the OLS model with state-level fixed effects finds that having a child support obligation is associated with a 17.73 percentage point decrease in …

General Aviation Maintenance Technician Fatigue And Work/Rest Periods, Blaise Eisenbeil

Theses and Dissertations

Fatigue has been studied extensively within the ranks of commercial airline pilots, and for them, regulations have been modified several times to include various rest and work periods. These regulations are often supplemented by union provisions found in contracts with airlines. Conversely, Aviation Maintenance Technicians (AMTs) have been largely overlooked, especially in the general aviation industry. The goals of this research project are to determine (a) if any rest/work rules are in place for 14 CFR (Code of Federal Regulations) Part 145 AMTs, and (b) the body of literature on fatigue in relation to operational errors by AMTs. Note: Any …

Civil Liability For Injuries Caused By Dogs After Tracey V. Solesky: New Path To The Future Or Back To The Past?, Alberto Bernabe

Seton Hall Journal of Legislation and Public Policy

No abstract provided.

Study Of Homogeneous Mineral Acid Dehydration Of Monosaccharides In A Cstr, Siddharth Sharad Bhat

Dissertations - ALL

Simple sugars (Aldohexoses/pentoses), (Ketohexoses/pentose) when subjected to a dehydration reaction, produce various compounds. An example of one such compound is 5-hydroxymethyl furfural. Such chemical products may be used in subsequent processing steps (hydrolysis, aldol condensation, hydrogenation and dehydration) to produce similarly structured condensed compounds that form the basis of complex molecules used in various industries such as production of fuels, chemical reagents and fertilizers. Most studies focus on heterogeneous packed beds and batch reactors to carry out dehydration reactions. This study illustrates use of a Continuous Stirred-Tank reactor to carry out such dehydration reactions. In order to maintain the homogenous …

Detecting At-Risk Drinking In University Primary Care: Validity Of The Audit-C, Clare Elizabeth Campbell

Dissertations - ALL

Research has shown that primary care physicians are more likely to discuss alcohol use with their patients when brief screens are routinely administered. One such screen, the Alcohol Use Disorder Identification Test-Consumption (AUDIT-C; Bush, Kivlahan, McDonnell, Fihn, & Bradley, 1998), has yet to be validated for detecting at-risk alcohol consumption and negative drinking consequences among students presenting to a university student health service for primary care. Accordingly, the proposed study aimed to assess the construct validity of the AUDIT-C among students (N = 387) recruited from Syracuse University's University Health Service (UHS). Receiver Operating Characteristic curve analyses were used to …

"We'd Always Return To This Center:" Understanding Urban Space As A Dakota Place In Mni Sota Makoce, Kelsey Marie Carlson

Dissertations - ALL

This thesis intends to bring to popular consciousness the historical and ongoing injustices committed against Indigenous peoples by sharing the knowledges and experiences of a number of Dakota people in Minnesota. Part landscape analysis, part ethnography, and by most substantially relying on narrative and lengthy excerpts from interviews, I challenge the dominant notion that Minnesota is a non-Native space. Rather, Mni Sota Makoce, the land where the waters reflect the sky, with a place called Bdote at its center, forms the traditional territory of the Dakota Oyate, the Dakota Nation. More specifically, this thesis tells a story about Dakota peoples' …

Deciphering The Neuroprotective Potential Of Interleukin-1Β (Il-1Β) Using In Vitro Murine Models Of Oxidative Stress, Twinkle Chowdhury

Dissertations - ALL

Interleukin-1β (IL-1β), a key cytokine driving neuroinflammation in the Central Nervous System (CNS), is enhanced in many neurological diseases/disorders, including but not limited to ischemic stroke, Parkinson's disease, Amyotrophic Lateral Sclerosis, Huntington's disease and Alzheimer's disease. The dominant view is that IL-1β contributes to and/or sustains pathophysiological processes. However, other studies demonstrate that IL-1β can play an important role in neural protection and repair. It may do so by modifying astrocyte behavior. Indeed, studies from our laboratory demonstrate that IL-1β increases the synthesis and release of the antioxidant molecule glutathione (GSH) from astrocytes and that IL-1β-treated astrocytes show increased resistance …

An Experimental Study On Thermal Stability Of Faee Biodiesel Fuel With Ethanol, Yujie Shen

Dissertations - ALL

Biodiesel fuel is usually synthesized from vegetable oil and animal fat, and now it has been widely used in tractors, trucks, buses and ships. Unlike traditional fossil fuels, biodiesel is more environment-friendly and it is renewable, which can help people solve the energy crisis to some extent.

Nowadays, supercritical esterification has become a novel way to produce biodiesel, but high temperature may cause the decomposition of biodiesel. Researchers mainly focus on studying the properties of fatty acid methyl ester (FAME), however, fatty acid ethyl ester (FAEE) biodiesel has only been slightly explored. So in this study, ethanol was used to …

Effects Of Ultrasound As Visual Feedback Of The Tongue On Generalization, Retention, And Acquisition In Speech Therapy For Rhotics, Greta Sjolie

Dissertations - ALL

Purpose: The purpose of this study was to provide an initial comparison of exposure to ultrasound visual feedback of the tongue and no exposure to ultrasound in speech therapy for postvocalic rhotics (the /r/ family of sounds). Effects of the two treatments on acquisition, retention, and generalization were explored in participants ages 7-9.

Methods: A single-subject randomized block design replicated across four participants was used. Each week for seven weeks, one session containing high frequency ultrasound use and one session containing no ultrasound use were randomly ordered. A Training Probe List and Generalization Probe List consisting of monosyllabic words, multisyllabic …

Coordination Chemistry In Biology And Medicine, Christopher Chu

Dissertations - ALL

PART I. Synthesis and Characterization of Novel Metal-Citrate Complexes and the Investigation of Metal-Citrate Transporters in Gram-Positive Bacteria

Abstract.

Syntheses of new barium, cadmium, calcium, cobalt, iron, lead, magnesium, manganese, nickel, and strontium citrate complexes have been attempted using different methods such as room temperature slow evaporation and hydrothermal reactions to create new metal-citrate complexes. Crystallizations were conducted under conditions varying metal and ligand concentrations, solution pH, temperature, solvents, and the presence of coligands. All structures of crystals obtained were characterized by X-ray crystallography. A novel lead-citrate complex was synthesized with a formula of (Na)[Pb5(C6H5O7)3(C6H6O7)(H2O)] 8H2O. The structure is two-dimensional …

Controlling Biofilm And Persister Cells By Targeting Cell Membranes, Ali Adem Bahar

Dissertations - ALL

The rapid increase in antibiotic resistant infections and the slowing pace of antibiotic development emphasize the need for alternative therapeutic agents to cure infectious diseases especially those caused by multidrug-resistant (MDR) strains. Bacteria obtain resistance to antibiotics through multiple mechanisms. One of intrinsic mechanisms of drug resistance is persister formation, by which bacterial cells enter a metabolically inactive stage and become highly tolerant to essentially all antibiotics, even at the concentrations that are hundreds of times higher than the lethal dose required to kill normal planktonic cells of the same strain. Persister cells in biofilms are even more difficult to …

Shape Memory Polymers As 2d Substrates And 3d Scaffolds For The Study Of Cell Mechanobiology And Tissue Engineering, Richard Mcclary Baker

Dissertations - ALL

Tissue engineering is a promising, fast-growing field that combines cells, signals, and scaffolds to regenerate damaged tissues. To develop new, functional, engineered tissues, it is becoming increasingly important to understand how cell-material interactions affect the cell mechanobiological response. As a result, recent efforts have focused on developing complex synthetic materials that can mimic the dynamic in vivo cell environment. In this work, shape memory polymers (SMPs) were employed to develop dynamic 2D substrates and 3D scaffolds that undergo programmed changes in shape under cell compatible conditions. These substrates and scaffolds were applied in vitro and in vivo to demonstrate their …

Effects Of An Expressive Writing Intervention Aimed At Improving Academic Performance By Reducing Test Anxiety, Stephanie Lauren Spielberger

Dissertations - ALL

This study examined the effectiveness of a brief, class-wide, expressive writing intervention aimed at improving academic performance and decreasing test anxiety. This study included 110 students from six undergraduate psychology classes. In the first phase of the study, students completed a trait test anxiety measure and a demographic survey. In the second phase of the study, students completed a pre-intervention state test anxiety measure, responded to a 10-minute writing prompt (expressive or neutral), and completed the same state test anxiety measure, and then were administered an in-class exam. Approximately half the students were randomly assigned to the expressive writing group, …

Composite Minimization: Proximity Algorithms And Their Applications, Feishe Chen

Dissertations - ALL

ABSTRACT

Image and signal processing problems of practical importance, such as incomplete

data recovery and compressed sensing, are often modeled as nonsmooth optimization

problems whose objective functions are the sum of two terms, each of which is the

composition of a prox-friendly function with a matrix. Therefore, there is a practical

need to solve such optimization problems. Besides the nondifferentiability of the

objective functions of the associated optimization problems and the larger dimension

of the underlying images and signals, the sum of the objective functions is not,

in general, prox-friendly, which makes solving the problems challenging. Many algorithms have been …

Characterization And Chemical Kinetic Analysis Of The Ignition Of Representative Conventional And Bio-Derived Fuels, Mazen Eldeeb

Dissertations - ALL

Fossil fuels are the main energy source in the world. However, they are responsible for negative environmental impacts, such as global climate change and rising sea levels. Biofuels are an environmentally friendly alternative which can substitute fossil fuels without major engine modications, especially in the transportation sector. Furans, a class of biofuels, are considered as possible alternative fuels for SI engines. They can be produced from sugars, derived from non-food biomass sources. This thesis is a contribution to fundamental characterization of their combustion properties.

Reactivity trends in furan combustion are established through ignition delay measurements of selected furans; 2,5-dimethyl furan …

Postemancipation Landscapes And Material Culture: The Bethel Community And The Benjamin W. Jackson Plantation, Sarah Elizabeth Loftus

Dissertations - ALL

This dissertation explores the history and archaeology of a postemancipation community that developed around the Benjamin W. Jackson Plantation in Bethel, Texas, particularly concentrating on the transformation of the landscape through the rise of black land ownership and material culture collected at two households occupied by generations of the Davis family. The Davises were tenant farmers whose ancestors were previously enslaved on the plantation and members of the family continued to occupy the lands through the 1950s. In the decades following emancipation the antebellum landscape of the Benjamin Jackson plantation and the Bethel community in East Texas were slowly transformed …

Butlers Of The Mohawk Valley: Family Traditions And The Establishment Of British Empire In Colonial New York, Judd David Olshan

Dissertations - ALL

Historians follow those tributaries of early American history and trace their converging currents as best they may in an immeasurable river of human experience. The Butlers were part of those British imperial currents that washed over mid Atlantic America for the better part of the eighteenth century. In particular their experience reinforces those studies that recognize the impact that the Anglo-Irish experience had on the British Imperial ethos in America. Understanding this ethos is as crucial to understanding early America as is the Calvinist ethos of the Massachusetts Puritan or the Republican ethos of English Wiggery. We don't merely suppose …