Digital Commons Network^™

Cell Cycle Regulation Of Retinal Progenitors; A Role For The Nance-Horan Syndrome Protein In Retinogenesis, Paul J. Vorster

Theses and Dissertations

The Nance-Horan syndrome gene (NHS) plays a role in lens, eye and brain development. To date, the function of NHS remains unclear. Recent evidence showed that p53 isoform, Δ113p53, inhibits abnormal cell growth during organogenesis. We show that NHS is expressed in the retinas of Danio rerio and Xenopus tropicalis during key stages of retinogenesis, and that knockdown of the gene resulted in a small eye phenotype in both species. Initially, knockdown of nhsb in zebrafish had no visible defects at 24hpf. But examination of the retina at 48hpf, we see a marked difference in size compared to control embryos. …

Fear, Funding And Ambiguity: The Policy Dilemmas Of Undocumented Students In Virginia Institutions Of Higher Education, Sybil C. Halloran

Theses and Dissertations

Although immigration is considered the responsibility and authority of the federal government, there is no clear federal policy regarding undocumented students and higher education. This leaves the power to regulate undocumented students in higher education to state governments. In Virginia, there is no specific, state-wide policy that addresses undocumented students and admission and enrollment in public higher education. Because of this, policies and practices related to the admission and enrollment of undocumented students are created at the university level. There is, however, state policy in Virginia related to legal immigration status and eligibility for in-state tuition. This creates a complex …

Tolerance Of Thymine Glycol At The Blunt Dna Double Strand Break For Nonhomologus End Joining Repair And Interference By Base Excision Repair, Sri Lakshmi Chalasani

Theses and Dissertations

Radiotherapy is the clinical application of the ionizing radiation to treat cancer. Ionizing radiation causes multiple modes of damage to the DNA damage such as SSBs, DSBs and modified bases such as thymine glycol. These lesions can exist as clusters in one or two helical turns of DNA. DNA double-strand breaks (DSBs) are extremely toxic to cells because they can lead to genomic rearrangements and even cell death. If base lesions accompany these DSBs, there will be a substantial hindrance for repair.

NHEJ is the primary DSB repair pathway in mammalian cells. HRR repairs single strand breaks (SSBs) or Double …

Adherence To And Competence In Cognitive Behavioral Therapy For Youth Anxiety: Psychometric Evaluation, Cassidy C. Arnold

Theses and Dissertations

Treatment integrity—the extent to which a treatment is delivered as it was intended—has long been recognized as critically important in treatment evaluation research, but has garnered increased attention in recent years within the context of dissemination and implementation science. However, the field’s development has been hindered by inadequate measurement tools. This project is focused on developing and evaluating the psychometric strength of two measures of treatment integrity. To evaluate the psychometric strength of the Cognitive-Behavioral Therapy for Youth Anxiety Therapist Adherence Scale (CBAY-A)and the Cognitive-Behavioral Therapy for Youth Anxiety Therapist Competence Scale (CBAY-C), 954 psychotherapy sessions from two treatment evaluation …

An Actor-Network Theory Approach In Investigating The Information Systems Perspective Of Anti-Money Laundering Compliance Through A Case Study Of The Foreign Account Tax Compliance Act (Fatca) Implementation In A Jordanian Local Bank, Muhammad Al-Abdullah

Theses and Dissertations

Implementation of the Foreign Account Tax Compliance Act (FATCA) goes beyond a technological modification to automate the identification of US clients and report their information to the IRS. FATCA implementation requires foreign financial institutions (FFIs) to learn the new requirements, to modify their organizational structures and their employees’ relationships and responsibilities, and to adjust the technology that helps the employees collect new FATCA-related information and to process that information so that it can be reported to the IRS in the correct format. In spite of that, research on FATCA implementation has focused on studying each constituent separately. However, according to …

Rogue Signal Threat On Trust-Based Cooperative Spectrum Sensing In Cognitive Radio Networks, David S. Jackson

Theses and Dissertations

Cognitive Radio Networks (CRNs) are a next generation network that is expected to solve the wireless spectrum shortage problem, which is the shrinking of available wireless spectrum resources needed to facilitate future wireless applications. The first CRN standard, the IEEE 802.22, addresses this particular problem by allowing CRNs to share geographically unused TV spectrum to mitigate the spectrum shortage. Equipped with reasoning and learning engines, cognitive radios operate autonomously to locate unused channels to maximize its own bandwidth and Quality-of-Service (QoS). However, their increased capabilities over traditional radios introduce a new dimension of security threats.

In an NSF 2009 workshop, …

A Comparison Of Obesity Interventions Using Energy Balance Models, Marcella Torres

Theses and Dissertations

An energy balance model of human metabolism developed by Hall et al. is extended to compare body composition outcomes among standard and proposed obesity interventions. Standard interventions include a drastic diet or a drastic diet with endurance training. Outcomes for these interventions are typically poor in clinical studies. Proposed interventions include a gradual diet and the addition of resistance training to preserve lean mass and metabolic rate. We see that resistance training, regardless of dietary strategy, achieves these goals. Finally, we observe that the optimal obesity intervention for continued maintenance of a healthy body composition following a diet includes a …

The Effects Of Nicotine Sequestration On The Dynamics Of Hyperparasitism In A Stage-Structured Model Of Manduca Sexta And Its Related Parasitoid Wasps, Mark P. Zimmerman

Theses and Dissertations

Two proposed models will be used to help answer a long observed question in the dynamics of \textit{Manduca sexta} and its related parasitoid wasps-Why is there a large difference in diversity in hyperparasitoid species between tobacco and other related plants such as tomato? Two stage structured differential equation models are presented. The first is a single patch model to study the changes in dynamics that occur between hosts, parasitoids, and hyperparasitoids as the amount of nicotine in the plant increases. The second is a two patch model that allows hyperparasitoids to choose between patches that are nicotine negative (i.e. tomato …

On-Field Signs And Symptoms Associated With Recovery Duration After Concussion In High School And College Athletes: A Critically Appraised Topic, Jaebin Shim, Deanna H. Smith, Bonnie Van Lunen

Rehabilitation Sciences Faculty Publications

Clinical Scenario: Over the past decade, sport-related concussions have received increased attention due to their frequency and severity over a wide range of athletics. Clinicians have developed return-to-play protocols to better manage concussions in young athletes; however, a standardized process projecting the length of recovery time after concussion has remained an elusive piece of the puzzle. The recovery times associated with such an injury once diagnosed can last anywhere from 1 wk to several months. Risk factors that could lead to protracted recovery times include a history of 1 or multiple concussions and a greater number, severity, and duration of …

2015-01-00 Concerns, Morehead State University. Staff Congress.

Staff Congress Records

Staff Congress concerns for January of 2015.

Effects Of A Training Program To Enhance Autonomy Supportive Behaviors Among Youth Soccer Coaches, Jody L. Langdon, Robert J. Schlote, Brandonn S. Harris, Glenn P. Burdette Iii, Sara Rothberger

Health Sciences & Kinesiology: Faculty Publications

This study aimed to evaluate the prevalence and implementation of a training emphasizing the use of autonomy supportive coaching behaviors among youth soccer coaches in game-play situations as well as evaluating its effects on motivational processes among athletes. Participants included youth sport soccer coaches and their intact teams. Coaches received a series of autonomy-supportive coaching training interventions based on successful programs in general and physical education (Reeve, Jang, Carrell, Jeon & Barch, 2004; Cheon, Reeve & Moon, 2012). Athletes completed questionnaires to assess perceived autonomy support, basic need satisfaction, and motivation (Harris & Watson, 2011). Observations indicated coaches were not …

The Destined Duke, Jennifer D. Glover

Liberal Studies (MA) Final Essays

The idea for what would become this fiction piece, The Destined Duke, occurred to me during my first graduate writing class at Hollins University with Professor Amanda Cockrell. I remember the first question she asked of us, her students, was in regard to what genre we loved to read and what we may be interested in writing. As I sat at the large class table about two-thirds around, I awaited my turn, listening to my fellow classmates and trying to determine if I was brave enough in a graduate writing class to admit that I love to read romance novels …

My Travels In The Holy Land, Bud Robinson

Heritage Material

No abstract provided.

Nuggets Of Gold, Bud Robinson

Heritage Material

No abstract provided.

A Pitcher Of Cream, Bud Robinson

Heritage Material

No abstract provided.

Sychar: An Holiness Camp Meeting, W. W. Cary

Heritage Material

No abstract provided.

The Way Of Power: A Series Of Lectures Delivered Before The Japan Convention For Deepening Of Spiritual Life, At Karuizawa, Stenographically Reported, John Paul

Heritage Material

No abstract provided.

Methodism And Bible Holiness, Ebenezer Myers

Heritage Material

No abstract provided.

Entire Sanctification From 1739 To 1900, S. L. C. Coward

Heritage Material

No abstract provided.

Sanctity Without Starch A Layperson's Guide To A Wesleyan Theology Of Grace, Robert G. Tuttle Jr.

Heritage Material

No abstract provided.

Wolverton's "Cosmas Of Prague: Narrative, Classicism, Politics" (Book Review), Mary Ann Buhler

The Christian Librarian

No abstract provided.

Sleiman's "Dauntless" (Book Review), Cynthia Hammell

The Christian Librarian

No abstract provided.

Schreiner's "Commentary On Hebrews: Biblical Theology For Christian Proclamation" (Book Review), Mark Sloneker

The Christian Librarian

No abstract provided.

Wilson's "Does Altruism Exist? Cultures, Genes, And The Welfare Of Others" (Book Review), Lisa Cutforth-Anderson

The Christian Librarian

No abstract provided.

Ramelli And Perkins' "Early Christian And Jewish Narrative: The Role Of Religion In Shaping Narrative Form" (Book Review), Lisa Cutforth-Anderson

The Christian Librarian

No abstract provided.

Beal's "First & Second Kings: Apollos Old Testament Commentary" (Book Review), Sean J. Mcnulty

The Christian Librarian

No abstract provided.

Miles' "A God Of Many Understandings?: The Gospel And A Theology Of Religions" (Book Review), Tiffany Pettis

The Christian Librarian

No abstract provided.

O'Malley's "The Jesuits: A History From Ignatius To The Present" (Book Review), Terry L. Christian

The Christian Librarian

No abstract provided.

Wheeler And Whaley's "The Great Commission To Worship: Biblical Principles For Worship-Based Evangelism" (Book Review), Gary Fitsimmons

The Christian Librarian

No abstract provided.

Quarles' "Illustrated Life Of Paul" (Book Review), Gary Fitsimmons

The Christian Librarian

No abstract provided.