Digital Commons Network^™

Serrula In Retrospect: A Historical Look At Scorpion Literature (Scorpiones: Orthosterni), Matthew R. Graham, Victor Fet

Euscorpius

Serrula, a small comb-like structure on the ventral aspect of cheliceral movable finger in scorpions, has often been overlooked or ignored. Scorpion genera that are currently known to possess serrula belong to six families: Chactidae, Euscorpiidae, Iuridae, Pseudochactidae, Superstitioniidae, and Vaejovidae. All relevant literature on scorpion serrula is reviewed, and serrula of representative scorpion taxa is illustrated by SEM images. We suggest that the inconsistency in reporting serrula is based on several factors (or combination thereof): (a) serrula tines can quite often be broken off partially or completely, especially in adults; (b) serrula can be vestigial and hardly visible under …

On The Poorly Known Genus Mesotityus González-Sponga, 1981 (Scorpiones: Buthidae), Luis F. De Armas, Fernando J. M. Rojas-Runjaic

Euscorpius

Examination of new available material (18 females and six males) of the rare Venezuelan scorpion Mesotityus vondangeli González-Sponga, 1981 (Buthidae) demonstrated that there are consistent taxonomic characters to consider it as a genus different from Tityus C. L. Koch, 1836 sensu stricto. Nevertheless, it shares important characters with species of the Tityus clathratus group (=subgenus Archaeotityus Lourenço, 2006). An emended diagnosis of Mesotityus is given, as well as data on natural history, meristic and morphometric variation.

From Lab To Pharmacy Shelves: The Story Of A Plant Derived Anticancer Drug, "Paclitaxel", Maira Junjua, Sana Jafar, Fazeelat Karamat, Faheem Ahmed

Journal of Bioresource Management

Paclitaxel (Taxol®) is a highly praised anticancer drug, known for its efficiency in treating different cancers. It belongs to a class of compounds called taxanes that are derived from the plants of the genus Taxus. This drug is now FDA approved, but there was a time when the name Taxol was less known to the scientific world. Taxol, being a unique molecule in its structure, properties and mechanism of action, has undergone more than 30 years of trials, and faced a lot of hurdles to leave the bench of a laboratory and reach the shelves of a pharmacy. This review …

Status And Future Management Of Grey Goral (Naemorhedus Goral Bedfordi) In Pakistan, Fakhar -I- Abbas, Afsar Mian, Tanveer Akhtar, Thomas P. Rooney

Journal of Bioresource Management

Himalayan grey goral (HGG: Naemorhedus goral bedfordi) is endemic to Himalyas and regarded as Endangered/ Threatened. Study was designed to collect information on population biology, habitat, food and behaviour of population of HGG distributed in Pakistan, trying to understand its present status and conservational potentials. Our data suggest that the population, habitat and the species has sufficient potentials for its survival in the area, if protection from human predation is afforded to the species. HGG population is isolated into 7-8 subpopulations and is facing male-biased mortality, therefore is likely to face bottleneck effects and subsequent population crash ascribed to …

Dna Protective Activity Of Peels Of Some Vegetables Wastes, Aisha Ishaq, Kainaat William

Journal of Bioresource Management

The present study was conducted by using kitchen wastes like peels of different vegetables e.g. cucumber, potato, carrot, chickpea, cauliflower and pea, to evaluate the phytochemical constituents, DNA protection ability and free radicals scavenging activity. Phytochemicals tests showed the presence of carbohydrates, amino acids, glycosides, alkaloids, tannins and steroids in all samples while phlobatannins, anthraquonines and saponins were absent. The DNA protection of samples was checked by DNA protection assay using plasmid pBR322. Cauliflower and cucumber showed best protection at each dilution. DPPH free radicals scavenging assay was used to evaluate the antioxidant activity of peel extract of vegetables. Carrot …

Taxonomic Position Of The Genus Sassanidotus Farzanpay, 1987 (Scorpiones: Buthidae), František Kovařík, Victor Fet

Euscorpius

Sassanidotus Farzanpay, 1987 is a valid genus closely related to Compsobuthus Vachon, 1949, with which it shares most characters including the shape of carinae on the carapace and mesosoma. The main difference is that Sassanidotus has only three granules located proximally to the terminal granule on the movable finger of pedipalp, whereas Compsobuthus and also Mesobuthus Vachon, 1950 have four such granules. Sassanidotus Farzanpay, 1987 includes two species, Sassanidotus zarudnyi (Birula, 1900) (type species) from Iran and Sassanidotus gracilis thus zarudnyi sarghadensis Birula, 1903, syn. n.) from Afghanistan, Iran, and Pakistan. The neotype is designated for S. zarudnyi.

Simultaneous Dynamic Optical Refraction And Biometry Of The Human Accommodative Response, Victor M. Hernandez

Open Access Dissertations

The ability of the crystalline lens to change shape and bring near objects into focus is known as accommodation. Over time, the deformability of the lens decreases, deteriorating near visual function. This condition is known as presbyopia. There are many ways in which presbyopia correction is addressed, but currently there does not exist a method capable of restoring a dynamic visual range. In order to better understand the accommodative process and evaluate future corrective approaches, we require a system capable of dynamically acquiring refraction and biometric information. The goal of this work was to design, develop, and test a system …

Evolutionary Dynamics Of Speciation And Extinction, Dawn Michelle King

Dissertations

Presented here is an interdisciplinary study that draws connections between the fields of physics, mathematics, and evolutionary biology. Importantly, as we move through the Anthropocene Epoch, where human-driven climate change threatens biodiversity, understanding how an evolving population responds to extinction stress could be key to saving endangered ecosystems. With a neutral, agent-based model that incorporates the main principles of Darwinian evolution, such as heritability, variability, and competition, the dynamics of speciation and extinction is investigated. The simulated organisms evolve according to the reaction-diffusion rules of the 2D directed percolation universality class. Offspring are generated according to one of three reproduction …

Ethylene, A Hormone At The Center-Stage Of Nodulation, Frédérique C. Guinel

Biology Faculty Publications

Nodulation is the result of a beneficial interaction between legumes and rhizobia. It is a sophisticated process leading to nutrient exchange between the two types of symbionts. In this association, within a nodule, the rhizobia, using energy provided as photosynthates, fix atmospheric nitrogen and convert it to ammonium which is available to the plant. Nodulation is recognized as an essential process in nitrogen cycling and legume crops are known to enrich agricultural soils in nitrogenous compounds. Furthermore, as they are rich in nitrogen, legumes are considered important as staple foods for humans and fodder for animals. To tightly control this …

Early Prevention Of Pressure Ulcers In The Emergency Department, Marie Fagan

Seton Hall University DNP Final Projects

Purpose: Pressure ulcers characterize a major health problem in clinical practice, which in turn, can have an impact on quality of life and health care costs (Dugaret, Videau, Faure, Gabinski, Bourdel-Marchasson & Salles, 2012). Pressure ulcers can develop during treatment regardless of the setting. They develop in long term facilities, family homes and hospitals. The purpose of this DNP project was to ensure patient health and safety by educating the primary emergency room nurses to at-risk individuals presenting to the Emergency Department and to initiate early intervention strategies. Significance of the Project: Until recently, there has been very little literature …

Initiating A Bystander Awareness Program At A State University, Kristine B. Sparks

Seton Hall University DNP Final Projects

Crime in schools, colleges and universities is a troublesome social problem. It affects not only those involved in the criminal incident, but it also inhibits societal growth and stability. To address this issue, the Campus Sexual Violence Elimination Act (SaVE Act) of 2013 requires that colleges participating in federal student aid programs must provide “primary prevention and awareness programs” for new students and employees, as well as ongoing crime prevention and awareness campaigns. Implementation was mandated to be started by October 1, 2014. Most prevention programs teach students how to avoid situations, abusive behaviors and potential attacks. This project initiates …

Transitional Care To Reduce 30-Day Heart Failure Readmissions Among The Long-Term Care Elderly Population, Shantha Franks

Seton Hall University DNP Final Projects

Throughout the nation, there is an increased focus on reducing preventable hospital readmissions. This initiative started with the Patient Protection and Affordable Care Act (PPACA) (CMS, 2014), which sets forth certain provisions for Medicare spending. Hospitals with higher than usual readmission rates, especially in terms of preventable readmissions, are receiving reductions in Medicare reimbursements (Stone & Hoffman, 2010, CMS, 2014). Congestive Heart Failure (CHF) or Heart Failure (HF) is recognized as a primary cause of 30-day hospital readmissions. Causes of HF readmission include inadequate patient education and planning for discharge, inappropriate medication reconciliation, and poor or inadequate follow-up in the …

Ethnic Differences In Maternal Adipokines During Normal Pregnancy, Xinhua Chen, Theresa O Scholl

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Two adipokines (adiponectin and resistin) have opposite relations with insulin resistance and inflammation. Our major focus was to determine whether there were detectable ethnic differences in maternal adipokines during pregnancy. We also explored the correlation of the adipokines with maternal glucose homeostasis, blood pressure and anthropometric parameters. Pregnant women (n = 1634) were from a large prospective cohort study in Camden NJ (African-American 36.8%; Hispanic 47.6%; Caucasian 15.6%). Serum adiponectin and resistin were measured at entry (week 16.8) and the 3rd trimester (week 30.7) using the Luminex xMapTechnology. Significant differences were observed among ethnic groups, controlling for confounding variables. African …

Improving Patient Care Outcomes To Reduce Recurrent Admissions Of Patients With Chronic Obstructive Pulmonary Disease, Lisa Maria Friedrich

Seton Hall University DNP Final Projects

Purpose:Transitional care is time-limited, with the goal of ensuring safety and health continuity for at-risk patients with chronic obstructive pulmonary disease (COPD) as they move from one setting to the next. An acute care episode of COPD ranges from relatively healthy adults to adults with multiple chronic conditions or those in the end-of-life phase. The primary quality concern of an urgent need to improve health care is in response to the gaps of sufficient experience to manage patients with COPD, leading to hospital readmissions. Implementation of standards of care for the improvement of health-related quality of life (HRQL) of COPD …

Collaborative Approaches To The Management Of Geospatial Data Collections In Canadian Academic Libraries: A Historical Case Study, Leanne Trimble, Cheryl Woods, Francine Berish, Daniel Jakubek, Sarah Simpkin

Western Libraries Publications

Special Issue: Geospatial Data Management, Curation, and Preservation - Part 2

The Ontario Council of University Libraries (OCUL) is a consortium of the twenty-one university libraries in Ontario, Canada. Since 1967, OCUL member institutions have worked together to share costs and workload through collective purchasing and licensing of information resources and more recently through the establishment of a shared digital infrastructure known as Scholars Portal. Under the auspices of OCUL, Ontario's university map librarians formed the OCUL Map Group in 1973 to seek opportunities to communicate and collaborate to improve the collections and services they offer their users. The opportunities …

Marijuana Legalization. Initiative Statute.

Initiatives

Legalizes marijuana under state law. Creates commission to regulate and license marijuana industry. Applies general retail sales taxes to marijuana, unless medical or dietary exemptions apply. Permits excise taxes on certain marijuana sales, up to 15% of retail price, and storage, up to 10% of wholesale price. Prohibits discrimination based on marijuana use. Restricts marijuana testing for job applicants and employees, or penalizing employees for off-duty use, unless they are in safety-sensitive occupations. Permits local regulation of marijuana businesses, including ban or limit on number with voter approval. Exempts medical marijuana collectives from licensing requirements. Summary of estimate by Legislative …

When Free Is Not For Me: Confronting The Barriers To Use Of Free Quitline Telephone Counseling For Tobacco Dependence, Christine Sheffer, Sharon Brackman, Charnette Lercara, Naomi Cottoms, Mary Olson, Luana Panissidi, Jami Pittman, Helen Stayna

Publications and Research

Remarkable disparities in smoking rates in the United States contribute significantly to socioeconomic and minority health disparities. Access to treatment for tobacco use can help address these disparities, but quitlines, our most ubiquitous treatment resource, reach just 1%–2% of smokers. We used community-based participatory methods to develop a survey instrument to assess barriers to use of the quitline in the Arkansas Mississippi delta. Barriers were quitline specific and barriers to cessation more broadly. Over one-third (34.9%) of respondents (n = 799) did not have access to a telephone that they could use for the quitline. Respondents reported low levels of …

Filter Presence And Tipping Paper Color Influence Consumer Perceptions Of Cigarettes, Richard J. O’Connor, Maansi Bansal-Travers, K. Michael Cummings, David Hammond, Jim Thrasher, Cindy Tworek

Faculty Publications

Background: Cigarettes are marketed in a wide array of packaging and product configurations, and these may impact consumers’ perceptions of product health effects and attractiveness. Filtered cigarettes are typically perceived as less hazardous and white tipping paper (as opposed to cork) often conveys ‘lightness’.

Methods: This study examined cigarette-related perceptions among 1220 young adult (age 18-35) current, ever, and never smokers recruited from three eastern U.S. cities (Buffalo NY, Columbia SC, Morgantown WV). Participants rated three cigarette sticks: two filtered cigarettes 85 mm in length, differing only in tipping paper color (cork versus white), and an unfiltered 70 mm cigarette. …

Pvt1 Exon 9: A Potential Biomarker Of Aggressive Prostate Cancer?, Adeodat Ilboudo, Jyoti Chouhan, Brian K. Mcneil, Joseph R. Osborne, Olorunseun O. Ogunwobi

Publications and Research

Prostate cancer (PCa) is the most commonly diagnosed cancer as well as the greatest source of cancer-related mortality in males of African ancestry (MoAA). Interestingly, this has been shown to be associated with single nucleotide polymorphisms around regions 2 and 3 of the 8q24 human chromosomal region. The non-protein coding gene locus Plasmacytoma Variant Translocation 1 (PVT1) is located at 8q24 and is overexpressed in PCa and, therefore, is also a candidate biomarker to explain the well-known disparity in this group. PVT1 has at least 12 exons that make separate transcripts which may have different functions, all of which are …

Results Of A Community Randomized Study Of A Faith-Based Education Program To Improve Clinical Trial Participation Among African Americans, Paula M. Frew, Jay T. Schamel, Kelli A. O'Connell, Laura A. Randall, Sahithi Boggavarapu

Environmental & Global Health Faculty Research

This is a report of a cluster randomized clinical trial evaluating the effectiveness of a church-based educational intervention aimed at improving African Americans’ (AA) participation in clinical trials. Two hundred and twenty-one AA subjects ages ≥50 years from six predominantly AA churches were randomized to intervention or control condition. The intervention included three educational sessions about clinical trials and health disparities; control participants completed questionnaires. Primary endpoints of the study were differences in individual subjects' intentions to obtain clinical trial information and intention to join a clinical trial, as determined by 10 point scale items at baseline, three and six …

Using An External Exposome Framework To Examine Pregnancy-Related Morbidities And Mortalities: Implications For Health Disparities Research, Tonny J. Oyana, Patricia Matthews-Juarez, Stephania A. Cormier, Xiaoran Xu, Paul D. Juarez

Faculty Publications

© 2015 by the authors; licensee MDPI, Basel, Switzerland. Objective: We have conducted a study to assess the role of environment on the burden of maternal morbidities and mortalities among women using an external exposome approach for the purpose of developing targeted public health interventions to decrease disparities. Methods: We identified counties in the 48 contiguous USA where observed low birthweight (LBW) rates were higher than expected during a five-year study period. The identification was conducted using a retrospective space-time analysis scan for statistically significant clusters with high or low rates by a Discrete Poisson Model. Results: We observed statistically …

Dunham Tavern Museum Governance Project, Stuart Mendel

All Maxine Goodman Levin School of Urban Affairs Publications

The Center for Nonprofit Policy & Practice (CNP&P) was formally engaged by board leaders of the Dunham Tavern Museum in 2014 to assist the organization with forming and performing the work to strengthen board governance. Gradually, a project work plan was created to conduct “small p” planning (not traditional strategic planning) to advance the interests of the organization.

• The mutually agreed upon work products facilitated by the CNP&P include the following elements:
• Board development, training, and priorities planning of strategic issues;
• Assist board members develop a board governance committee;
• Create a mutually agreeable work plan for the committee;
• Provide staffing …

Measuring Usability In The Database Review Process: Results From A Pilot, Ilana Stonebraker

Libraries Faculty and Staff Scholarship and Research

The objective of this study is to examine the impact of incorporating user experience study methods into library database purchase and renewal. Purdue University Libraries introduced a heuristic evaluation into an existing yearly database review. Commonly used in usability and human factors engineering, heuristic evaluation is an innovative and dynamic method for librarians to evaluate electronic resources and provide expert feedback to database vendors. A form was developed to streamline the process for the librarians involved. In total, eight librarians evaluated 37 databases as a pilot project. This paper describes the outcome of the pilot.

Gliopathy Of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus., Lawrence C. Kenyon, Kaushiki Biswas, Kenneth S Shindler, Manasi Nabar, Marjorie Stout, Susan T Hingley, Judith B Grinspan, Jayasri Das Sarma

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it is not clear whether the mechanism of this disease pathology involves direct viral infection of oligodendrocytes. Detailed studies of glial cell tropism of MHV are presented, demonstrating that direct MHV infection of oligodendrocytes differs between demyelinating (RSA59) and non-demyelinating (RSMHV2) viral strains both in vitro and in vivo. Our results indicate that direct injury of mature oligodendrocytes is an important mechanism of virus-induced demyelination. In vivo, RSA59 infection was identified in spinal cord gray and white …

Response: No Need To Match: A Comment On Bach, Nicholson, And Hudson's “Affordance-Matching Hypothesis”, Patric Bach, Toby Nicholson, Matthew Hudson

School of Psychology

No abstract provided.

Reliability And Validity Of Neurobehavioral Function On The Psychology Experimental Building Language Test Battery In Young Adults, Brian J. Piper, Shane Mueller, Alexander R. Geerken, Kyle L. Dixon, Gregory Kroliczak, Reid H. Olsen, Jeremy K. Miller

Michigan Tech Publications, Part 1

Background. The Psychology Experiment Building Language (PEBL) software consists of over one-hundred computerized tests based on classic and novel cognitive neuropsychology and behavioral neurology measures. Although the PEBL tests are becoming more widely utilized, there is currently very limited information about the psychometric properties of these measures.

Methods. Study I examined inter-relationships among nine PEBL tests including indices of motor-function (Pursuit Rotor and Dexterity), attention (Test of Attentional Vigilance and Time-Wall), working memory (Digit Span Forward), and executive-function (PEBL Trail Making Test, Berg/Wisconsin Card Sorting Test, Iowa Gambling Test, and Mental Rotation) in a normative sample (N = 189, …

Fungal Melanin: What Do We Know About Structure?, Joshua D. Nosanchuk, Ruth E. Stark, Arturo Casadevall

Publications and Research

The production of melanin significantly enhances the virulence of many important human pathogenic fungi. Despite fungal melanin’s importance in human disease, as well as melanin’s contribution to the ability of fungi to survive in diverse hostile environments, the structure of melanin remains unsolved. Nevertheless, ongoing research efforts have progressively revealed several notable structural characteristics of this enigmatic pigment, which will be the focus of this review. These compositional and organizational insights could further our ability to develop novel therapeutic approaches to combat fungal disease and enhance our understanding of how melanin is inserted into the cell wall.

Hot Spot Mutation In Tp53 (R248q) Causes Oncogenic Gain-Of-Function Phenotypes In A Breast Cancer Cell Line Derived From An African American Patient, Nataly Shtraizent, Hiroshi Matsui, Alla Polotskaia, Jill Bargonetti

Publications and Research

African American (AA) breast cancer patients often have triple negative breast cancer (TNBC) that contains mutations in the TP53 gene. The point mutations at amino acid residues R273 and R248 both result in oncogenic gain-of-function (GOF) phenotypes. Expression of mutant p53 (mtp53) R273H associates with increased cell elasticity, survival under serum deprivation conditions, and increased Poly (ADP ribose) polymerase 1 (PARP1) on the chromatin in the AA-derived TNBC breast cancer cell line MDA-MB-468. We hypothesized that GOF mtp53 R248Q expression could stimulate a similar phenotype in the AA-derived TNBC cell line HCC70. To test this hypothesis we depleted the R248Q …

Rna Sequencing Analysis Of The Msl2msl3, Crl, And Ggps1 Mutants Indicates That Diverse Sources Of Plastid Dysfunction Do Not Alter Leaf Morphology Through A Common Signaling Pathway, Darron R. Luesse, Margaret E. Wilson, Elizabeth S. Haswell

Biology Faculty Research

Determining whether individual genes function in the same or in different pathways is an important aspect of genetic analysis. As an alternative to the construction of higher-order mutants, we used contemporary expression profiling methods to perform pathway analysis on several Arabidopsis thaliana mutants, including the mscS-like (msl)2msl3 double mutant. MSL2 and MSL3 are implicated in plastid ion homeostasis, and msl2msl3 double mutants exhibit leaves with a lobed periphery, a rumpled surface, and disturbed mesophyll cell organization. Similar developmental phenotypes are also observed in other mutants with defects in a range of other chloroplast or mitochondrial functions, including …

Planning And Monitoring Of Urban Development: The Role Of The Housing Price Index, Tomi Deutsch

Economic and Business Review

In this paper the real estate market in Slovenia and selected Slovenian city municipalities is analyzed with the goal of establishing whether or not it is possible to use the Housing Price Index as an indicator of urban development. The analysis shows that the real estate market in the Slovenian city municipalities has in recent decades been subject to a number of changes with a long-term effect. The analysis further proves that under certain conditions the Housing Price Index can serve as one of the indicators policy makers could use in planning and monitoring of urban development.