Digital Commons Network^™

Thermal Patterns Constrain Diurnal Behavior Of A Ground-Dwelling Bird, J. Matthew Carroll, Craig A. Davis, R. Dwayne Elmore, Samuel D. Fuhlendorf, Eric T. Thacker

Wildland Resources Faculty Publications

Recently, gaining knowledge about thermal refuges for vulnerable species has been a major focal point of ecological studies, and this focus has been heightened by predicted temperature increases associated with global climate change. To better understand how organisms respond to thermal landscapes and extremes, we investigated the thermal ecology of a gallinaceous bird species (northern bobwhite; Colinus virginianus, hereafter bobwhite) during a key life history period. Specifically, our study focused on the brood-rearing period of precocial bobwhite chicks associated with brood-attending adults. We measured site-specific black bulb temperatures (Tbb) and vegetation characteristics across 38 brood tracking days and 68 random …

Hypercalcemia Of Malignancy: An Update On Pathogenesis And Management, Aibek E. Mirrakhimov

Internal Medicine Faculty Publications

Hypercalcemia of malignancy is a common finding typically found in patients with advanced stage cancers. We aimed to provide an updated review on the etiology, pathogenesis, clinical presentation, and management of malignancy-related hypercalcemia. We searched PubMed/Medline, Scopus, Embase, and Web of Science for original articles, case reports, and case series articles focused on hypercalcemia of malignancy published from 1950 to December 2014. Hypercalcemia of malignancy usually presents with markedly elevated calcium levels and therefore, usually severely symptomatic. Several major mechanisms are responsible for the development of hypercalcemia of malignancy including parathyroid hormone-related peptide-mediated humoral hypercalcemia, osteolytic metastases-related hypercalcemia, 1,25 Vitamin …

Science Career Options, Lori Tyler Gula

UNH Today Archive

No abstract provided.

The Heart Failure Overweight/Obesity Survival Paradox : The Missing Sex Link, Amanda R. Vest, Yuping Wu, Roy Hachamovitch, James B. Young, Leslie Cho

Mathematics and Statistics Faculty Publications

Objectives: This study sought to determine whether body mass index (BMI) has a differential impact on survival for females versus males with advanced systolic heart failure (HF). Background: Females have a survival advantage in HF, the mechanisms of which are unclear. There is also a proposed “obesity survival paradox” in which excess adiposity promotes HF survival. Methods: We reviewed 3,811 patients with left ventricular ejection fraction ≤40% who had undergone cardiopulmonary exercise testing between 1995 and 2011. The endpoint was all-cause mortality. Multivariable analysis was performed using a Cox proportional hazards model. Because of the nonlinearity of BMI, a restricted …

Gathering The Needles Evaluating The Impact Of Gold Open Access Content With Traditional Subscription Journals, Jill Emery, Alison Bobal

Library Faculty and Staff Publications and Presentations

Investigating the use of gold open access content within subscription content has been a near impossible task until the adoption of the COUNTER 4 statistics in 2014. By reviewing the COUNTER JR1 GOA 2014 reports, two librarians evaluate the gold open access usage at their respective institutions from the following publishers: Elsevier, NPG, Sage, Springer, and Wiley. This initial investigation will be a benchmark for future studies to see if there is any impact on subscribed content or if usage is limited to non-subscribed content from these providers. Attendees will become familiar with the JR1 GOA reports from COUNTER as …

Mckee Minute November 2015, Southern Adventist University

McKee Minute – McKee Library This Month

The November 2015 McKee Minute features several books on "The History & Mystery of Time," including The Little Book of Time by Klaus Mainzer and Splitting the Second by Tony Jones. Featured films include The Adventures of Huck Finn and The Life and Work of Mark Twain. Featured Adventist periodicals include Adventist Frontiers and Journal of Adventist Education. This month's spotlight is on chemistry.

Meaning In Life In Psychotherapy: The Perspective Of Experienced Psychotherapists, Clara E. Hill, Yoshi Kanazawa, Sarah Knox, Iris Schauerman, Darren Loureiro, Danielle James, Imani Carter, Shakeena King, Suad Razzak, Melanie Scarff, Jasmine Moore

College of Education Faculty Research and Publications

Objective

Our goal was to explore the meaning experienced psychotherapists derive from providing psychotherapy, their beliefs about the role of meaning in life (MIL) in psychotherapy, how they worked with MIL with a client who explicitly presented concerns about MIL, and how they worked with a different client for whom MIL was a secondary and more implicit concern.

Method

Thirteen experienced psychotherapists were interviewed and data were analyzed using consensual qualitative research.

Results

Therapists derived self-oriented meaning (e.g., feeling gratified, fulfilled, connected) and other-oriented meaning (helping others, making the world a better place) from providing psychotherapy. They believed that MIL …

Handedness For Unimanual Grasping In 564 Great Apes: The Effect On Grip Morphology And A Comparison With Hand Use For A Bimanual Coordinated Task, Adrien Meguerditchian, Kimberley A. Phillips, Amandine Chapelain, Lindsay M. Mahovetz, Scott Milne, Tara Stoinski, Amanda Bania, Elizabeth Lonsdorf, Jennifer Schaeffer, Jamie Russell, William D. Hopkins

Faculty Articles

A number of factors have been proposed to influence within and between species variation in handedness in non-human primates. In the initial study, we assessed the influence of grip morphology on hand use for simple reaching in a sample of 564 great apes including 49 orangutans Pongo pygmaeus, 66 gorillas Gorilla gorilla, 354 chimpanzees Pan troglodytes and 95 bonobos Pan paniscus. Overall, we found a significant right hand bias for reaching. We also found a significant effect of the grip morphology of hand use. Grasping with the thumb and index finger was more prevalent in the right compared to left …

The Reverse Transcription Signature Of N-1-Methyladenosine In Rna-Seq Is Sequence Dependent, Ralf Hauenschild, Lyudmil Tserovski, Katharina Schmid, Kathrin Thuring, Marie-Luise Winz, Sunny Sharma, Karl-Dieter Entian, Ludvine Wacheul, Denis L.J. Lafontaine, James T. Anderson, Juan Alfonzo, Andreas Hildebrandt, Andres Jaschke, Yuri Motorin, Mark Helm

Biological Sciences Faculty Research and Publications

The combination of Reverse Transcription (RT) and high-throughput sequencing has emerged as a powerful combination to detect modified nucleotides in RNA via analysis of either abortive RT-products or of the incorporation of mismatched dNTPs into cDNA. Here we simultaneously analyze both parameters in detail with respect to the occurrence of N-1-methyladenosine (m¹A) in the template RNA. This naturally occurring modification is associated with structural effects, but it is also known as a mediator of antibiotic resistance in ribosomal RNA. In structural probing experiments with dimethylsulfate, m¹A is routinely detected by RT-arrest. A specifically developed RNA-Seq protocol …

A Cytotoxic, Co-Operative Interaction Between Energy Deprivation And Glutamate Release From System XC− Mediates Aglycemic Neuronal Cell Death, Trista L. Thorn, Yan He, Nicole A. Jackman, Doug Lobner, James A. Hewett, Sandra J. Hewett

Biological Sciences Faculty Research and Publications

The astrocyte cystine/glutamate antiporter (system x_c⁻) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation. The purpose of this study was to determine the mechanism by which this occurred. Using pure astrocyte cultures, as well as, mixed cortical cell cultures containing both neurons and astrocytes, we found that neither an enhancement in system x_c⁻ expression nor activity underlies the excitotoxic effects of aglycemia. In addition, using three separate bioassays, we demonstrate no change in the ability of glucose-deprived astrocytes—either cultured alone or with neurons—to remove glutamate from the extracellular space. Instead, we …

Condylar Hyperplasia: An Updated Review Of The Literature, Luis Eduardo Almeida, Joseph Zacharias, Sean Pierce

School of Dentistry Faculty Research and Publications

Condylar hyperplasia (CH) is a rare disorder characterized by excessive bone growth that almost always presents unilaterally, resulting in facial asymmetry. Classification of the different types of CH can differ depending on the authors. Correct diagnosis is critical in determining the proper treatments and timing. This paper is a review of the recent literature on the epidemiology, etiology, diagnosis, classification, and surgical treatments of CH.

Deanotes, College Of Science And Technology, Armstrong State University

College of Science & Technology Dean's Notes (Archived)

No abstract provided.

Ethical Considerations For Practitioners Advising On Esa Issues, Irma S. Russell

Faculty Works

All lawyers are subject to the rules of ethics and professional conduct of their jurisdictions of practice. Regulation of lawyers is within the jurisdiction of the states, typically the supreme court of each state. Many state supreme courts have adopted customized versions of the professional rules from the American Bar Association’s Model Rules of Professional Conduct (“Model Rules”). While the Model Rules are not law in any jurisdiction, most states base their ethics codes on the Model Rules. In fact, all jurisdictions, with the exception of California, now base their ethics rules on the Model Rules. Additionally, courts have inherent …

Residential Proximity To Major Roadways Is Associated With Increased Levels Of Ac133+ Circulating Angiogenic Cells, Natasha Dejarnett, Ray Yeager, Daniel J. Conklin, Jongmin Lee, Timothy E. O’Toole, James Mccracken, Wes Abplanalp, Sanjay Srivastava, Daniel W. W. Riggs, Jasmit Shah

Brain and Mind Institute

OBJECTIVES: Previous studies have shown that residential proximity to a roadway is associated with increased cardiovascular disease risk. Yet, the nature of this association remains unclear, and its effect on individual cardiovascular disease risk factors has not been assessed. The objective of this study was to determine whether residential proximity to roadways influences systemic inflammation and the levels of circulating angiogenic cells.

APPROACH AND RESULTS: In a cross-sectional study, cardiovascular disease risk factors, blood levels of C-reactive protein, and 15 antigenically defined circulating angiogenic cell populations were measured in participants (n=316) with moderate-to-high cardiovascular disease risk. Attributes of roadways surrounding …

Mapping Choices: Carbon, Climate, And Rising Seas: Our Global Legacy, B H. Strauss, S Kulp, A Levermann

State & Federal Reports and Publications

Carbon emissions causing 4 degrees Celsius of warming (7.2 degrees Fahrenheit) — a business-asusual scenario — could lock in enough eventual sea level rise to submerge land currently home to 470 to 760 million people globally. Carbon cuts resulting in the proposed international target of 2 °C warming (3.6 °F) would reduce the rise locked in so that it would threaten areas now occupied by as few as 130 million people. This contrast is one expression of what is at stake in the December 2015 global climate talks in Paris. This report builds closely on a paper first published online …

Oil And Gas Mineral Leasing And Development On The Outer Continental Shelf Of The United States, Anthony C. Marino, C. Jacob Gower

LSU Journal of Energy Law and Resources

No abstract provided.

2015-November-01-Faculty/Staff Professional Activities, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Individual, Family, And Culture Level Contributions To Child Physical Abuse And Neglect: A Longitudinal Study In Nine Countries, Jennifer E. Lansford, Jennifer Godwin, Liliana Maria Uribe Tirado, Arnaldo Zelli, Suha M. Al-Hassan, Dario Bacchini, Anna Silvia Bombi, Marc H. Bornstein, Lei Chang, Kirby Deater-Deckard, Laura Di Giunta, Kenneth A. Dodge, Patrick S. Malone, Paul Oburu, Concetta Pastorelli, Ann T. Skinner, Emma Sorbring, Sombat Tapanya, Liane Peña Alampay

Psychology Department Faculty Publications

This study advances understanding of predictors of child abuse and neglect at multiple levels of influence. Mothers, fathers, and children (N = 1,432 families, M age of children = 8.29 years) were interviewed annually in three waves in 13 cultural groups in nine countries (China, Colombia, Italy, Jordan, Kenya, Philippines, Sweden, Thailand, and the United States). Multilevel models were estimated to examine predictors of (a) within-family differences across the three time points, (b) between-family within-culture differences, and (c) between-cultural group differences in mothers’ and fathers’ reports of corporal punishment and children’s reports of their parents’ neglect. These analyses addressed …

Ion Exchange-Precipitation For Nutrient Recovery From Dilute Wastewater, A. T. Williams, Daniel Zitomer, Brooke K. Mayer

Civil and Environmental Engineering Faculty Research and Publications

Regulated phosphorus (P) and nitrogen (N) discharges and the cost of fertilizer provide economic drivers for nutrient removal and recovery from wastewater. This study used ion exchange (IX) in dilute (domestic) wastewater to concentrate nutrients with subsequent recovery by struvite precipitation. This is the first tertiary wastewater treatment study directly comparing P removal using a range of Fe, Cu, and Al-based media followed by clinoptilolite IX columns for N removal and precipitation using the combined regenerants. Phosphate removal prior to breakthrough was 0.5–2.0 g P L_media⁻¹, providing effluent concentrations −1 PO₄-P and −1 NH_{4 …}

The Physiology And Psychology Of Exercise And Parkinson's Disease, Jess Gibson

Senior Honors Theses

Parkinson’s disease is one of the most common degenerative neurological disorders and is currently lacking a cure. While physicians have long debated over the best treatment for Parkinson’s symptoms, treatments such as oral medication and deep brain stimulation have not yet shown to be a permanent solution to the disease. Recently, exercise has emerged as a contender in the fight against Parkinson’s and physicians and physiotherapists have been investigating the benefits of prescribing exercise programs to patients in an effort to slow progression of Parkinson’s symptoms. The following presents an analysis of the effects of exercise on Parkinson’s symptoms and …

Rapid And Repeatable Shifts In Life-History Timing Of Rhagoletis Pomonella (Diptera: Tephritidae) Following Colonization Of Novel Host Plants In The Pacific Northwestern United States, Monte Mattsson, Glen R. Hood, Jeffery L. Feder, Luis A. Ruedas

Biology Faculty Publications and Presentations

Host shifts of phytophagous insect specialists to novel plants can result in divergent ecological adaptation, generating reproductive isolation and potentially new species. Rhagoletis pomonellafruit flies in eastern North America underwent a host shift ~160 ya from native downy hawthorn (Crataegus mollis) to introduced, domesticated apple (Malus domestica). Divergent selection on diapause phenology related to the earlier fruiting time of apples versus downy hawthorns resulted in partial allochronic reproductive isolation between the fly races. Here, we test for how rapid and repeatable shifts in life-history timing are driving ecological divergence of R. pomonella in the Pacific …

Detection Methods And Intestinal Adherence Of Non-O157 Shiga Toxin-Producing Escherichia Coli, Zachary R. Stromberg

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

Shiga toxin-producing Escherichia coli (STEC) are enteric pathogens of humans. Cattle serve as a reservoir and harbor STEC in their intestines. Intimin-positive STEC are referred to as enterohemorrhagic E.coli (EHEC). Seven serogroups (O26, O45, O103, O111, O121, O145, and O157) account for the majority of illness due to STEC and are hereafter referred to as STEC/EHEC-7. To improve detection, enrichment broths were compared for supporting growth of STEC-7 and STEC O104:H4 (STEC-8). In pure culture, STEC enriched in trypticase soy broth (TSB) had significantly greater growth compared to TSB containing antimicrobials. In fecal samples, E. coli broth enrichment yielded …

Mechanism Of Action Of Two Flavone Isomers Targeting Cancer Cells With Varying Cell Differentiation Status, Timothy M. Lejeune, Hei Yin Tsui, Laura B. Parsons, Gerald E. Miller, Crystal Whitted, Kayla E. Lynch, Robert E. Ramsauer, Jasmine U. Patel, Jarrett E. Wyatt, Doris S. Street, Carolyn B. Adams, Brian Mcpherson, Hei Man Tsui, Julie A. Evans, Christopher Livesay, Ruben D. Torrenegra, Victoria E. Palau

ETSU Faculty Works

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted by death receptor signals and bypasses the mitochondria. These two pathways are closely related to cell proliferation and survival signaling cascades, which thereby constitute possible targets for cancer therapy. In previous …

Antarctic Streams As A Potential Source Of Iron For The Southern Ocean, William Berry Lyons, Kelsey R. Dailey, Kathleen A. Welch, Kelly M. Deuerling, Susan A. Welch, Diane M. Mcknight

Geography and Geology Faculty Publications

Due to iron’s role in oceanic primary production, there has been great interest in quantifying the importance of Fe in regions where concentrations are very low and macronutrients, nitrate and phosphate, are available. Measurements of filterable (i.e., <0.4 μm) Fe concentrations in streams from Taylor Valley, McMurdo Dry Valleys, Antarctica, suggest that coastal-zone stream Fe input to the Southern Ocean could potentially play an important role in primary production in nearshore regions. Filterable Fe (fFe) data from streams in the McMurdo Dry Valleys were used to represent glacier meltwater that flows through ice-free landscape with the potential of transporting Fe to the Antarctic coastal zone. Estimates of potential fFe flux to the Antarctic Peninsula region using our mean fFe concentration of 10.6 µg L^–1 combined with an estimate of ice-free area for the Antarctic Peninsula result in an fFe flux of 1.2 × 10⁷ g yr^–1. Although small compared to iceberg and aeolian Fe fluxes, future stream input to the Southern Ocean could increase due to glacier retreat and melting, thus increasing the fFe flux from glacier meltwater streams.

Panorama November 2015, Southern Adventist University

Panorama Parent Newsletter

This issue of the Panorama parent newsletter discusses working with mentors and advisers, highlights the LEAP alumni mentor program, includes a staff profile on Career Counselor Daniel Olson, and highlights student mentors.

A Path To Empathy: Child And Family Communication, Sarah Ann Stone

Theses and Dissertations

This longitudinal study examined the association between communication in the family on the development of empathy in young children. Co-regulation and family expressiveness measured communication in parent-child dyads at age 12 months (N = 186), 24 months (N = 100), and 36 months (N = 78). A follow-up was conducted at 60 months (N = 47) to measure empathy-related responding in children. Co-regulation styles change over time, generally increasing in the most engaged, two-way style of communication (symmetrical) and decreasing in one-sided and less engaged types. Greater family expressiveness predicted higher levels of empathy as observed in an empathy-eliciting experiment, …

Alternating Direction Implicit Method With Adaptive Grids For Modeling Chemotaxis In Dictyostelium Discoideum, Christopher F. Loomis

Theses and Dissertations

Dictyostelium discoideum (Dd) is a model organism, studied for reasons from cell movement to chemotaxis to human disease control. Creating a computer model of the life cycle of Dd has garnered great interest, one part of which is the Aggregation Stage, where thousands of amoeba gather together to form a slug. Chemotaxis is the mechanism through which this is accomplished. This thesis develops two- and three-dimensional alternating direction implicit code which solves the diffusion equation on an adaptive grid. The calculated values for both two and three dimensions are checked against the actual solution and error results are provided. Comparisons …

The Importance Of Analyzing Neighbor Competitive Response In The Target–Neighbor Experimental Design, Kevin J. Berry, Michele R. Dudash

Natural Resource Management Faculty Publications

The role of competition in community structure and species interactions is universal. However, how one quantifies the outcome of competitive interactions is frequently debated. Here, we review the strengths and weaknesses of the target– neighbor design, a type of additive design where one of the competing species is reduced to a single individual and where controls and analyses are used for the target, but not for the neighbors. We conducted a literature review to determine how the target–neighbor design has been typically used and analyzed. We found that historically, targets were often smaller than neighbors and introduced after neighbor establishment; …

The Anatomy Of Porcine And Human Larynges: Structural Analysis And High Resolution Magnetic Resonance Imaging Of The Recurrent Laryngeal Nerve, Nena Lundgreen Mason

Theses and Dissertations

The recurrent laryngeal nerve (RLN) innervates all the intrinsic muscles of the larynx that are responsible for human vocalization and language. The RLN runs along the tracheoesophageal groove bilaterally and is often accidentally damaged or transected during head and neck surgical procedures. RLN palsy and vocal cord paralysis are the most common and serious post op complications of thyroid surgeries. Patients who suffer from RLN injury can develop unilateral or bilateral vocal fold paralysis (BVFP). Theoretically, selective reinnervation of the posterior cricoarytenoid muscle would be the best treatment for BVFP. The phrenic nerve has been shown in several studies to …

The Homeoprotein Dlx3 And Tumor Suppressor P53 Co-Regulate Cell Cycle Progression And Squamous Tumor Growth, Paul W. Bible, E. Palazzo, M. Kellett, C. Cataisson, A. Gormley, V. Pietroni, Et Al.

Computer Science Faculty publications

Epidermal homeostasis depends on the coordinated control of keratinocyte cell cycle. Differentiation and the alteration of this balance can result in neoplastic development. Here we report on a novel DLX3-dependent network that constrains epidermal hyperplasia and squamous tumorigenesis. By integrating genetic and transcriptomic approaches, we demonstrate that DLX3 operates through a p53-regulated network. DLX3 and p53 physically interact on the p21 promoter to enhance p21 expression. Elevating DLX3 in keratinocytes produces a G1-S blockade associated with p53 signature transcriptional profiles. In contrast, DLX3 loss promotes a mitogenic phenotype associated with constitutive activation of ERK. DLX3 expression is lost in human …