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Talk Don’T Touch? Considerations For Children’S Attorneys On The Physical Touch Of Clients, Andrea L. Dennis

Scholarly Works

Researchers focused on the representation of children and attorneys for children have taken great pains to explore issues surrounding the attorney-child client relationship and recommend strategies and policies supporting positive development of the relationship. Notwithstanding the breadth of available information, almost no attention has been aimed at whether attorneys should physically touch their clients. This article fills that gap.

This Article consists of three parts. Part I describes the literature commanding attorneys for children to develop quality relationships with their clients. These works recognize that young clients seek good relationships with their attorneys, but that barriers to creating quality relationships …

Adiponectin Protects Against Paraquat-Induced Lung Injury By Attenuating Oxidative/Nitrative Stress., Rong Yao, Yaxiong Zhou, Yarong He, Yaowen Jiang, Peng Liu, Lei Ye, Zhijie Zheng, Wayne Bond Lau, Yu Cao, Zhi Zeng

Department of Emergency Medicine Faculty Papers

The specific mechanisms underlying paraquat (PQ)-induced lung injury remain unknown, which limits understanding of its cytotoxic potential. Although oxidative stress has been established as an important mechanism underlying PQ toxicity, multiple antioxidants have proven ineffective in attenuating the deleterious effects of PQ. Adiponectin, which shows anti-oxidative and antinitrative effects, may have the potential to reduce PQ-mediated injury. The present study determined the protective action of globular domain adiponectin (gAd) on PQ-induced lung injury, and attempted to elucidate the underlying mechanism or mechanisms of action. BALB/c mice were administered PQ, with and without 12 or 36 h of gAd pre-treatment. The …

A Mathematical Investigation Of The Drivers Of Lyme Disease Ecology At Two Ecologically Contrasting Sites, Malia Joy Carpio

Public Health Theses

INTRODUCTION: Lyme disease is an emerging tick-borne disease of increasing concern in the United States. In order to create and to implement effective public health interventions for Lyme disease, there must be a better understanding of the factors driving pathogen transmission.

OBJECTIVES: The primary objectives of this study were to determine how presence/absence of “super-spreaders” and observed differences between two ecologically contrasting sites influence Borrelia burgdorferi transmission.

METHODS: A next generation matrix R0 model was parameterized with field data from an island site (Block Island, Rhode Island) and a mainland site (Connecticut) in order to generate R0 estimates. A local …

Five-Year Resistance Trends Of Bacterial Isolates In Kigali, Rwanda, Makeda Aminah Carroll

Public Health Theses

Antimicrobial resistance (AMR), the phenomenon of decreased sensitivity to pharmaceutical agents that kill or inhibit the growth of bacterial pathogens, is a serious threat to public health worldwide. Many countries, including Rwanda, lack current information on antibiotic sensitivity profiles that would greatly aide clinicians and policy-makers. The current study aims to describe the time trends of antibiotic sensitivity for the isolates of six different bacterial pathogens from patients at King Faisal Hospital in Kigali, Rwanda and to make inference about future patterns of drug resistance in the study setting, to guide physicians in their prescribing practices and provide baseline data …

Extended Conventional Therapy In Adult Xlh Patients, Jessica Ann Connor

Public Health Theses

Context: Treatment of X-linked hypophosphatemia (XLH) with active vitamin D metabolites and phosphate can partially correct skeletal deformities. It is unclear if therapy influences the occurrence of two major long-term morbidities in XLH: enthesopathy and dental disease.

Objective: To investigate the relationship between treatment and enthesopathy and dental disease in adult XLH patients.

Design: Observational and cross-sectional.

Setting: Academic medical center’s hospital research unit.

Participants: 52 XLH patients aged >= 18 at time of study.

Interventions: None

Main outcome measures: Number of enthesopathy sites identified by radiographic skeletal survey and dental disease severity (>5 or <=5 dental abscesses), identified historically.

Methods: Associations between proportion …

A Case-Control Study To Assess Risk Factors For Community-Associated Clostridium Difficile Infection, Samantha Greissman

Public Health Theses

INTRODUCTION: Clostridium difficile infection (CDI), initially thought to be acquired in the hospital, has occurred often in persons not recently hospitalized. Community-associated CDI (CA-CDI) may affect healthy individuals who lack the traditional risk factors for health care-associated CDI (HA-CDI). Risk factors for CA-CDI have yet to be fully identified.

OBJECTIVES: The objective of this study was to assess the risk factors for CA-CDI in the small Connecticut sample of a larger multi-state case-control study being conducted by the Emerging Infections Programs, and to help inform analysis of the larger study.

METHODS: A matched case-control study was conducted of consenting individuals. …

Maternal Passive Smoking And Risk Of Small For Gestational Age Among Non-Smoking Chinese Women, Huang Huang

Public Health Theses

Maternal active smoking is an established risk factor for small for gestational age (SGA). The role of maternal passive smoking in SGA, however, is unclear. The present study analyzed data from a birth cohort study conducted in Lanzhou, China between 2010 and 2012 including 8,638 non-smoking women who delivered singleton live births. Among those, 775 were SGA and 7,863 were appropriate for gestational age (AGA). Multivariate logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs). Potential confounding variables included in the final models were maternal age, education, employment status during pregnancy, parity, maternal …

Effect Of Exercise Vs. Attention-Control On Depression Symptomatology In Ovarian Cancer Survivors: The Women’S Activity And Lifestyle Study In Connecticut (Walc), Meghan B. Hughes

Public Health Theses

Background: With no effective screening tool, ovarian cancer survivors often suffer from unpleasant treatment-related side effects that influence quality of life. Increased physical activity has been associated with lower depression scores in ovarian cancer survivors. However, to date, no randomized controlled trial assessing the effect of exercise on depression has been conducted in this population. The Women’s Activity and Lifestyle Study in Connecticut (WALC) was a randomized trial examining the impact of exercise vs. attention-control on quality of life, body composition, and cancer biomarkers in ovarian cancer survivors. This analysis examined the effect of exercise on depression scores.

Methods: We …

It Takes Two?: Exploring The Supportive Role Of Fathers During Pregnancy And Its Effect On Birth Outcomes Among Young Couples, Grace Kim

Public Health Theses

Few studies have evaluated the relationship between prenatal paternal support and adverse birth outcomes among young couples. Traditionally, paternal support has been measured based on pregnancy wantedness and the presence of the father’s name on the child’s birth certificate. However, these indices may not capture key components of paternal support. The current study developed a paternal support index that expands the traditional view of parental support by incorporating other forms of support, including financial support, accompanying the mother to prenatal care visits, labor/birth classes, ultrasound appointments, and the father’s presence at the child’s birth. We examined its association with various …

Sex Differences Among Adult Influenza Hospitalizations Associated With Age, Race, And Socioeconomic Status In 14 Us Sites, 2010-2012, Kelly Elizabeth Kline

Public Health Theses

BACKGROUND: Previous studies have shown sex differences in influenza hospitalizations, but sex differences across the United States by demographic characteristics have not been well-established. We investigated potential sex differences across 14 FluSurv-NET (FSN) sites that conduct active population-based surveillance for laboratory-confirmed influenza-associated hospitalizations among residents of 76 counties in 2010-2012, stratifying by age, race, and census tract-level poverty.

METHODS: We used 6,292 laboratory-confirmed adult (>18 years) cases collected by the 14 FSN sites during the 2010-11 and 2011-12 influenza seasons linked to 2010 Census data to calculate overall age-adjusted and age-specific incidence and incidence rate ratios (IRRs) for sex …

Non-Destructive Dna Extraction Methods That Yield Dna Barcodes In Spiders, Reva Ann Bork

Honors Program Theses

DNA barcodes are short sequences of nucleotides that differ from species to species (Hebert et al., 2003; Hebert & Gregory, 2005). DNA barcoding is very important in helping to reconstruct phylogenetic trees and to confirm the identity of threatened or endangered species in the wild. Additionally, it has become increasingly popular in the food industry to test the accuracy of the food being sold in fast food chains (Wong and Hanner, 2008). For scientific purposes, nondestructive DNA extraction techniques need to be explored because they allow for preservation of the voucher specimen, which is particularly important for rare or extinct …

Relative Importance Of Phenotypic Trait Matching And Species' Abundances In Determining Plant - Avian Seed Dispersal Interactions In A Small Insular Community, Aaron González-Castro, Suann Yang, Manuel Nogales, Tomas A. Carlo

Biology

Network theory has provided a general way to understand mutualistic plant-animal interactions at the community level. However, the mechanisms responsible for interaction patterns remain controversial. In this study we use a combination of statistical models and probability matrices to evaluate the relative importance of species morphological and nutritional (phenotypic) traits and species abundance in determining interactions between fleshyfruited plants and birds that disperse their seeds. The models included variables associated with species abundance, a suite of variables associated with phenotypic traits (fruit diameter, bird bill width, fruit nutrient compounds), and the species identity of the avian disperser. Results show that …

Identification Of Allorecognition Loci In Neurospora Crassa By Genomics And Evolutionary Approaches, Elizabeth Hutchison

Biology

Understanding the genetic and molecular bases of the ability to distinguish self from nonself (allorecognition) and mechanisms underlying evolution of allorecognition systems is an important endeavor for understanding cases where it becomes dysfunctional, such as in autoimmune disorders. In filamentous fungi, allorecognition can result in vegetative or heterokaryon incompatibility, which is a type of programmed cell death that occurs following fusion of genetically different cells. Allorecognition is genetically controlled by het loci, with coexpression of any combination of incompatible alleles triggering vegetative incompatibility. Herein, we identified, characterized, and inferred the evolutionary history of candidate het loci in the filamentous fungus …

Large Carbon Release Legacy From Bark Beetle Outbreaks Across Western United States, Bardan Ghimire, Christopher A. Williams, G. James Collatz, Melanie Vanderhoof, John Rogan, Dominik Kulakowski, Jeffrey G. Masek

Geography

Warmer conditions over the past two decades have contributed to rapid expansion of bark beetle outbreaks killing millions of trees over a large fraction of western United States (US) forests. These outbreaks reduce plant productivity by killing trees and transfer carbon from live to dead pools where carbon is slowly emitted to the atmosphere via heterotrophic respiration which subsequently feeds back to climate change. Recent studies have begun to examine the local impacts of bark beetle outbreaks in individual stands, but the full regional carbon consequences remain undocumented for the western US. In this study, we quantify the regional carbon …

Interactions Among Spruce Beetle Disturbance, Climate Change And Forest Dynamics Captured By A Forest Landscape Model, Christian Temperli, Thomas T. Veblen, Sarah J. Hart, Dominik Kulakowski, Alan J. Tepley

Geography

The risk of bark beetle outbreaks is widely predicted to increase because of a warming climate that accelerates temperature-driven beetle population growth and drought stress that impairs host tree defenses. However, few if any studies have explicitly evaluated climatically enhanced beetle population dynamics in relation to climate-driven changes in forest composition and structure that may alter forest suitability for beetle infestation. We synthesized current understanding of the interactions among climate, spruce beetles (Dendroctonus rufipennis) and forest dynamics to parameterize and further advance the bark beetle module of a dynamic forest landscape model (LandClim) that also integrates fire and wind disturbance …

Reconstructing Neuronal Connectivity From Calcium Imaging Data Using Generalized Transfer Entropy, Jina Li

Public Health Theses

The reconstruction of neuronal connectivity is a very interesting and important topic in neuroscience as it helps with understanding neuronal circuit and function. With the advancement of calcium fluorescence imaging technique, we can now observe the dynamical activity of hundreds of neurons in vivo in one setting, which provides a foundation for inferring connectivity within a community or network. Poor signal-to-noise ratio and low frame rate with respect to neurons’ actual firing rate are challenges that come with calcium imaging data. Here we review several methods that can be applied to calcium imaging data, without the direct need for converting …

Introduction To The Modeling And Analysis Of Complex Systems, Hiroki Sayama

Milne Open Textbooks

Keep up to date on Introduction to Modeling and Analysis of Complex Systems at http://bingweb.binghamton.edu/~sayama/textbook/!

Introduction to the Modeling and Analysis of Complex Systems introduces students to mathematical/computational modeling and analysis developed in the emerging interdisciplinary field of Complex Systems Science. Complex systems are systems made of a large number of microscopic components interacting with each other in nontrivial ways. Many real-world systems can be understood as complex systems, where critically important information resides in the relationships between the parts and not necessarily within the parts themselves. This textbook offers an accessible yet technically-oriented introduction to the modeling and …

Microgravity Testing Of A Phase Change Reference On The International Space Station, T. Shane Topham, Gail E. Bingham, Harri Latvakoski, Igor Podolski, Vladimir S. Sychev, Andre Burdakin

Space Dynamics Laboratory Publications

Orbital sensors to monitor global climate change during the next decade require low drift rates for onboard thermometry, which is currently unattainable without on-orbit recalibration. Phase change materials (PCM), such as those that make up the ITS-90 standard, are seen as the most reliable references on the ground and could be good candidates for orbital recalibration. Space Dynamics Lab (SDL) has been developing miniaturized phase change references capable of deployment on an orbital blackbody for nearly a decade. To determine if and how microgravity will affect the phase transitions, SDL conducted experiments with ITS-90 standard material (gallium, Ga) on the …

General Anesthesia: A Literature Review - Induction, Mechanism, Agents, And Effects, Sylvie Yaacoub

Senior Honors Theses and Projects

No abstract provided.

Intellectual Disability And Sexuality: The Missing Link, Megan Hoorn

Senior Honors Theses and Projects

Research literature documents the varied perspectives of caregivers, educators, health professionals, community members, and family members regarding intellectual disability and sexuality. Many aspects of disability and sexuality, even intellectual disability and sexuality, are well documented. But what are the perspectives and experiences regarding sexuality of those who have intellectual disabilities? There is a void when it comes to the voices of people labeled as having intellectual disabilities regarding their own sexuality; their perspectives have not been described. This research study explores the existing literature that discusses the perspectives of others (parents, caregivers, educators, medical professionals, the general community, etc.) and …

Interventions In The Enhancement Or Preservation Of Motor Skill Learning In Those With Mild Dementia, Dinah Hudson

Senior Honors Theses and Projects

The aim of this research is to provide a resource on current available data regarding methods used for enhancing or preserving motor learning in those with Alzheimer's dementia (AD). A decline in motor skill learning is associated with increased morbidity in the AD population. The implementation of interventions such as multisensory environments (MSE), physiotherapy, and physical activity may prove beneficial in stalling the inevitable degeneration of motor skills in this population. These interventions then may indirectly increase levels of activities of daily living, autonomy, and the quality of life of AD patients. The importance of familiarizing individuals with this knowledge …

The Synthesis And Characterization Of Dual-Modified Carboxymethylcellulose For Bioadhesive Applications, Fabrice Bernard

Dissertations and Theses

Reparative medical techniques, in conjunction with existing and emerging tissue adherents and sealants, offer practicing physicians a wide variety of tools to improve the functionality, performance, and safety of surgical interventions. Carboxymethylcellulose (CMC) is a plant-derived polymer that is cytocompatible, biocompatible, biodegradable, and inexpensive. The need for a non-toxic but strongly adherent material motivated the development of an injectable bioadhesive system containing CMC modified with functional methacrylate and aldehyde groups that could potentially be used as an annulus fibrosus sealant or as a supplement to existing wound closure materials. After modification, the polymer was characterized via NMR spectroscopy, Schiff’s base …

Chemotaxis Of Central Nervous System-Derived Tumor Cells Within Controlled Microenvironments, Jennifer Rico Varela

Dissertations and Theses

Medulloblastoma (MB) is a malignant pediatric brain tumor known for its aggressive metastatic potential. Despite the well-documented migration of MB cells to other parts of the brain and spinal column, MB chemotaxis is poorly understood. Herein, we examined the in vitro migratory and cellular responses of MB-derived cells to external signaling of Epidermal Growth Factor (EGF), hepatocyte growth factor (HGF), platelet-derived growth factor (PDGF-BB), and the stromal cell-derived factors 1-alpha (SDF-1). Experiments utilized transwell assays and immunocytochemistry to identify receptor activation in MB migration, and used a microfluidic platform to examine directionality, trajectory, and gradient- dependence of motile cells. Data …

Factors Influencing Self-Care Behaviors Of African Americans With Heart Failure: A Photovoice Project, Aimee Woda, Ruth Ann Belknap, Kristin Haglund, Margaret Sebern, Ashley Lawrence

College of Nursing Faculty Research and Publications

Objectives

The purpose of this study was to understand the influences of heart failure (HF) self-care among low income, African Americans.

Background

Compared to all other racial groups, African Americans have the highest risk of developing HF, coupled with high mortality and morbidity rates.

Methods

Using the photovoice method, participants related important lifestyle factors through photography. The participants and researcher met for reflection and discussion 2 h per week for six weeks.

Results

Four themes emerged: family support gives me the push I need, social interaction lifts me up, improving my mind to lift depression can improve my heart, and …

Assessment Of Injection Behavior Of Commercially-Available Bone Bsms For Subchondroplasty Procedures, Dinely A. Colon

Dissertations and Theses

Subchondroplasty is a procedure that utilized bone substitutes materials (BSMs) or bone cement to correct bone defects in the subchondral bone. The two main materials used to compose BSMs are poly-methyl-methacrylate (PMMA) and calcium phosphate cement (CaP). Currently, there is no optimal bone material substitute in the market that can provide both the adequate mechanical support and the right viscosity to reach the affected area in the subchondral bone. In addition, there is also no established parameter for their proper use, based on the defect size and location. PMMA possesses comparable mechanical properties to bone (i.e. 96 MPa in compressive …

Can Gender-Stereotyped Depictions Of Occupations In Primary School Textbooks Help Shape Students' Career Choice In The Dominican Republic?, Hurtado Pérez Nohemí

Dissertations and Theses

No abstract provided.

Empirical Investigation Of Samhsa’S (Substance Abuse And Mental Health Services Administration) Model Of Wellness, Dipanjana Das

Dissertations and Theses

The quest to operationalize the construct of wellness has been elusive. Part of the difficulty resides in the way wellness has been conceptualized in the literature, using different non-overlapping models. Another drawback is that many existing models are not based on solid empirical evidence. The current study addressed these limitations by assessing the empirical validity of SAMHSA’s (Substance Abuse and Mental Health Services Administration) model of wellness. We created an instrument to assess wellness based on a thorough review of the literature that serves as the basis of the SAMHSA model that can be used to assess wellness. Findings revealed …

Effects Of Acetyl Salicyclic Acid On Drosophila Models Of Cancer-Inflammation, Roma Rajwani

Dissertations and Theses

Chronic inflammation is a fundamental condition underlying many human disease pathologies including diabetes, cancer, and neurodegeneration. Indeed, one of the most commonly-used anti-inflammatory drugs, aspirin, has been shown to be effective in the treatment of many cancers. To understand the mechanistic linkages between inflammation and cancer, we used Drosophila models in which hyperactive immune signaling causes overproliferation of the hematopoietic system leading to the production of inflammatory blood tumors. In mutant animals, hematopoietic cells divide uncontrollably and exhibit pre-mature differentiation giving rise to large sticky cells. Some mutant cells infiltrate and adhere to cells of the fat body. The fat …

Effects Of Temperature Stress On Coral Fluorescence And Reflectance, Andrea Gomez

Dissertations and Theses

Around the world, climate change, land-based pollution and fishing impacts are recognized as principal threats to coral reef ecosystems. Sea surface temperatures, in particular, are expected to change dramatically over the next decades and result in high coral mortality in some regions. Through controlled experiments, I examined changes in coral fluorescence and reflectance in response to water temperature alterations to assess the potential of employing these signatures as a diagnostic tool to measure coral health. At the NOAA Coral Culture and Collaborative Research Facility, I conducted controlled laboratory-based heat stress experiments on three Caribbean species of coral: Acropora cervicornis, Orbicella …

Characterization Of The Interaction Between Ftsz-Ring Stabilizer Zapc And The Conserved Protease Clpxp In E. Coli Cytokinesis, Andrea Cardenas Arevalo

Dissertations and Theses

Cell division in bacteria requires the assembly of a macromolecular protein machinery at midcell that is spatiotemporally regulated during the bacterial cell cycle. Central to the process of division is the assembly of a cytokinetic ring-like structure, termed the Z-ring, formed by polymers of the essential tubulin-homolog FtsZ. Polymerization of FtsZ is regulated by a number of proteins that bind FtsZ and regulate its assembly/disassembly mechanisms. Despite being extensively studied, the molecular nature of the diverse protein-protein interactions that regulate the assembly of FtsZ during early stages of division is not well understood. Here, I focus on an FtsZ-ring stabilizer …