Entire DC Network | Open Access Articles | Digital Commons Network™

Suppression Of Β3-Integrin In Mice Triggers A Neuropilin-1-Dependent Change In Focal Adhesion Remodelling That Can Be Targeted To Block Pathological Angiogenesis, Tim S. Ellison, Samuel J. Atkinson, Veronica Steri, Benjamin M. Kirkup, Michael E J Preedy, Robert T. Johnson, Christina Ruhrberg, Dylan R. Edwards, Jochen G. Schneider, Katherine Weilbaecher, Stephen D. Robinson

Open Access Publications

No abstract provided.

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Carpal Tunnel Syndrome And Computer Exposure At Work In Two Large Complementary Cohorts, Z. Mediouni, J. Bodin, Ann Marie Dale, E. Herquelot, M. Carton, A. Leclerc, N. Fouquet, C. Dumontier, Y. Roquelaure, Bradley A. Evanoff, A. Descatha

Open Access Publications

No abstract provided.

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Evaluation Of Genetic Susceptibility Of Common Variants In Cacna1d With Schizophrenia In Han Chinese, Fanglin Guan, Lu Li, Chuchu Qiao, Gang Chen, Tinglin Yan, Tao Li, Tianxiao Zhang, Xinshe Liu

Open Access Publications

No abstract provided.

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Impact Of Vitamin D Supplementation On Adiposity In African-Americans, P D. Chandler, J B. Scott, B F. Drake, K Ng, A T. Chan, B W. Hollis, K M. Emmons, E L. Giovannucci, C S. Fuchs, G G. Bennett

Open Access Publications

No abstract provided.

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Somatic Chromosomal Translocation Between Ewsr1 And Fli1 Loci Leads To Dilated Cardiomyopathy In A Mouse Model, Miwa Tanaka, Shuichi Yamaguchi, Yukari Yamazaki, Hideyuki Kinoshita, Koichiro Kuwahara, Kazuwa Nakao, Patrick Y. Jay, Tetsuo Noda, Takuro Nakamura

Open Access Publications

No abstract provided.

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The Role Of Conduct Disorder In The Relationship Between Alcohol, Nicotine And Cannabis Use Disorders, J. D. Grant, M. T. Lynskey, P. A. F. Madden, E. C. Nelson, L. R. Few, K. K. Bucholz, D. J. Statham, N. G. Martin, A. C. Heath, A. Agrawal

Open Access Publications

No abstract provided.

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Higher Throughput Quantification Of Neutralizing Antibody To Herpes Simplex Viruses, Tamara P. Blevins, Michelle C. Mitchell, Maria Korom, Hong Wang, Yinyi Yu, Lynda A. Morrison, Robert B. Belshe

Open Access Publications

No abstract provided.

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A Genetically Modified Adenoviral Vector With A Phage Display-Derived Peptide Incorporated Into Fiber Fibritin Chimera Prolongs Survival In Experimental Glioma, Julius W. Kim, J. Robert Kane, Jacob S. Young, Alan L. Chang, Deepak Kanojia, Ramin A. Morshed, Jason Miska, Atique U. Ahmed, Irina V. Balyasnikova, Yu Han, Lingjiao Zhang, David T. Curiel, Maciej S. Lesniak

Open Access Publications

No abstract provided.

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Cross-Reactivity Of Filariais Ict Cards In Areas Of Contrasting Endemicity Of Loa Loa And Mansonella Perstans In Cameroon: Implications For Shrinking Of The Lymphatic Filariasis Map In The Central African Region, Samuel Wanji, Nathalie Amvongo-Adjia, Benjamin Koudou, Abdel Jelil Njouendou, Patrick W. Chounna Ndongmo, Jonas A. Kengne-Ouafo, Fabrice R. Datchoua-Poutcheu, Bridget Adzemye Fovennso, Dizzle Bita Tayong, Fanny Fri Fombad, Peter U. Fischer, Peter I. Enyong, Moses Bockarie

Open Access Publications

No abstract provided.

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Cralbp Supports The Mammalian Retinal Visual Cycle And Cone Vision, Yunlu Xue, Susan Q. Shen, Jonathan Jui, Alan C. Rupp, Leah C. Byrne, Samer Hattar, John G. Flannery, Joseph C. Corbo, Vladimir J. Kefalov

Open Access Publications

No abstract provided.

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Physical Activity Affects Brain Integrity In Hiv+ Individuals, Mario Ortega, Laurie M. Baker, Florin Vaida, Robert Paul, Brian Basco, Beau M. Ances

Open Access Publications

No abstract provided.

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Sexual Selection And Cancer Biology, Joshua B. Rubin

Open Access Publications

No abstract provided.

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An Intrinsic Case Study Into The Appropriateness Of A Bespoke Training Model As An Approach To Supporting The Postgraduate Demonstrator In Developing Pedagogical Skills Suitable For Undergraduate Scientific Laboratories., Barry Ryan

Theses

Postgraduate demonstrators (PGDs) are crucial to the smooth running of undergraduate teaching laboratories; however, they are oftentimes exiled to superficial duties such as enforcing health and safety and procedural instruction. The aim of this intrinsic case study was to characterise the support required by postgraduate demonstrators (PGDs) to develop the key pedagogical skills that would assist them in effectively demonstrating undergraduate science teaching labs. Through supporting PGD development, it is hoped to centralise the PGD in the undergraduate teaching lab and set in place the foundations for a move towards undergraduate teaching labs that encompass aspects of tailored research in …

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“The Relationship Between Approaches To Learning And Assessment Outcomes In Undergraduate Optometry Students”, Linda Moore

Theses

A cross-sectional quantitative study was implemented to identify and analyse student approaches to learning (SALs) in the four stages of an undergraduate optometry honours degree programme. Study results will be used to inform optometric educators of the SAL trends of this student cohort. Seventy-three undergraduate optometry students participated in the study. Individual participant SAL scores were calculated using the shortened Study Process Questionnaire (R-SPQ-2F) for a semester-long academic module identified for each programme stage. Only R-SPQ-2F main scale SAL scores measuring the deep approach (DA) and surface approach (SA) were included in the final analyses, due to poor internal consistency …

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Nanotechnology Solutions For Global Water Challenges, Aine Whelan, Niall B. Mcguinness, Mary Garvey, Honey John, Chun Zao, Geshan Zhang, Dionysios D. Dionysiou, J. Anthony Byrne, Suresh C. Pillai

Books/Book chapters

The lack of clean and safe drinking water is responsible for more deaths than war, terrorism and weapons of mass destruction combined. This suggests contaminated water poses a significant threat to human health and welfare. In addition, standard water disinfection approaches such as sedimentation, filtration, and chemical or biological degradation are not fully capable of destroying emerging contaminants (e.g. pesticides, pharmaceutical waste products) or certain types of bacteria (e.g. Cryptosporidium parvum). Nanomaterials and nanotechnology based devices can potentially be employed to solve the challenges posed by various contaminants and microorganisms. Nanomaterials of different shapes, namely nanoparticles, nanotubes, nanowires and fibers …

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Binding Of Dna By A Dinitro-Diester Calix[4]Arene: Denaturation And Condensation Of Dna, Mary Deasy, Pilar Lopez-Cornejo, F J. Ostos, J A. Lebron, M L. Moya

Articles

A study of a dinitro-diester calix[4]arene (5,17-(3-nitrobenzylideneamino)-11,23-di-tert-butyl- 25,27-diethoxycarbonyl methyleneoxy-26,28-dihydroxycalix[4]arene) interaction with calf-thymus DNA was carried out using several techniques. The measurements were done at various molar ratios X=[calixarene]/[DNA]. Results show diverse changes in the DNA conformation depending on the X value. Thus, at low macrocycle concentration, the calixarene binds to the polynucleotide. This interaction, mainly in groove mode, weakens the hydrogen bonds between the base pairs of the helix inducing the denaturation of the double strands, as well as the condensation of the macromolecule, from an extended coil state to a globular state. An opposite effect is observed …

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Critical Race Theory: A Strategy For Framing Discussions Around Social Justice And Democratic Education, Wesley Crichlow

Stream 2: Curriculum

The increasing diversity of our classrooms means we must learn to work with, and across, cultural, racial and gendered differences, without falling into diversity management. This paper employs Critical Race Theory (CRT) and paradigmatic frameworks to address social crises in our classrooms—thus demonstrating how we can value (i.e., not erase) our differences and equitably share power in the classroom. Employing an CRT intersectional analysis, I will explore the social, economic, and cultural dimensions of racial (in) justice in diverse contexts (within frameworks that recognize the salience of social identities including, but not limited to, class, and race, ethnicity, gender, sexuality, …

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Time Zones, Game Start Times, And Team Performance: Evidence From The Nba, Andrew Nutting, Joseph Price

Economics Faculty Research and Scholarship

Research has found that, controlling for team quality, NBA visiting teams win more often when playing to the east of their home time zones and less often when playing to the west. We reaffirm this finding for 1991-2002. Results show that only these seasons’ day games, and not their far more frequent night games, featured a significant relationship between time zone and visiting team win probability. We hypothesize that some of these day-game effects were biological in origin. The 2002-2013 seasons featured no significant relationship between time zones and visiting team win probability for either day or night games.

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Moving Beyond Causes: Optimality Models And Scientific Explanation, Collin Rice

Philosophy Faculty Research and Scholarship

A prominent approach to scientific explanation and modeling claims that for a model to provide an explanation it must accurately represent at least some of the actual causes in the event's causal history. In this paper, I argue that many optimality explanations present a serious challenge to this causal approach. I contend that many optimality models provide highly idealized equilibrium explanations that do not accurately represent the causes of their target system(s). Furthermore, in many contexts, it is in virtue of their independence of causes that optimality models are able to provide a better explanation than competing causal models. Consequently, …

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Autonomous Statistical Explanations And Natural Selection, André Ariew, Collin Rice, Yasha Rohwer

Philosophy Faculty Research and Scholarship

Shapiro and Sober ([2007]) claim that Walsh, Ariew, Lewens, and Matthen (henceforth WALM) give a mistaken, a priori defense of natural selection and drift as epiphenomenal. Contrary to Shapiro and Sober’s claims, we first argue that WALM’s explanatory doctrine does not require a defense of epiphenomenalism. We then defend WALM’s explanatory doctrine by arguing that the explanations provided by the modern genetical theory of natural selection are ‘autonomous-statistical explanations’ analogous to Galton’s explanation of reversion to mediocrity and an explanation of the diffusion ofgases. We then argue that whereas Sober’s theory of forces is an adequate description of Darwin’s theory, …

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Clinical Encounters With Immigrants: What Matters For U.S. Psychiatrists., Carolina Hausmann-Stabile, Peter J. Guarnaccia

Graduate School of Social Work and Social Research Faculty Research and Scholarship

About 3.2 percent of the population across the globe are migrants. Today, unprecedented numbers of people are relocating in the U.S. and more than ever, psychiatrists find themselves caring for immigrant patients. International migration is a multilayered issue that often has implications for the mental health of migrants. Thus, there is an increasing interest in understanding how the different factors associated with migration processes affect the mental health outcomes of immigrants. We group these factors into three categories: immigrant process, clinical encounter, and mental health services. When possible, we incorporate a gendered and life span perspective and suggest avenues for …

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Cherokee Freedmen And The Color Of Belonging, Lolita Buckner Inniss

Law Faculty Articles and Essays

This Article addresses the Cherokee Nation and its historic conflict with the descendants of its former black slaves, designated Cherokee Freedmen. This Article specifically addresses how historic discussions of black, red, and white skin colors, designating the African-ancestored, aboriginal (Native American), and European-ancestored people of the United States have helped to shape the contours of color-based national belonging among the Cherokee. The Cherokee past practice of black slavery and the past and continuing use of skin color-coded belonging not only undermines the coherence of Cherokee sovereignty, identity, and belonging but also problematizes the notion of an explicitly aboriginal way of …

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The Green Chemistry And Filipino Approach To High School Experiments In Saint Paul College Pasig, Ronald G. Santos, Armando M. Guidote Jr

Chemistry Faculty Publications

This paper is a call for teachers to initiate measures in improving the quality of high school chemistry education in the Philippines and that is by going back to practical laboratory work. The experiment presented in this paper is a proof to the possibility of tailor-made experiments that integrate principles of green chemistry. Integrating green chemistry concepts in the design of high school chemistry experiments makes students aware of the responsibility that goes with the use and production of chemicals. Moreover, the experiment was designed to consciously integrate aspects of Filipino culture, values, and traditions. Such enculturation of chemistry by …

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Ecological Perspectives And Children’S Use Of The Internet: Exploring Micro To Macro Level Analysis, Brian O'Neill

Articles

Age-old debates on children’s encounters with media technologies reveal a long, fractured and contentious tradition within communication and media studies. Despite the fact there have been studies of e ects of media use by children since the earliest days of broadcasting, the subject remains under-theorised, poorly represented in the literature and not widely understood in media policy debates. Old debates have intensi ed in relation to the study of children and the internet. Pitted between alarmist accounts of risks, excessive use and harmful e ects on the one hand and the many accounts about „digital natives” and the transformational power …

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Raman Micro-Spectroscopy For Rapid Screening Of Oral Squamous Cell Carcinoma, Luis Felipe Carvalho, Franck Bonnier, Kate O'Callaghan, Jeff O'Sullivan, Stephen Flint, Hugh Byrne, Fiona Lyng

Articles

Raman spectroscopy can provide a molecular-level fingerprint of the biochemical composition and structure of cells with excellent spatial resolution and could be useful to monitor changes in composition for dysplasia and early, non-invasive cancer diagnosis (carcinoma in situ), both ex-vivo and in vivo. In this study, we demonstrate this potential by collecting Raman spectra of nucleoli, nuclei and cytoplasm from oral epithelial cancer (SCC- 4) and dysplastic (pre-cancerous, DOK) cell lines and from normal oral epithelial primary cell cultures, in vitro, which were then analysed by principal component analysis (PCA) as a multivariate statistical method to discriminate the spectra. Results …

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Investigation Into The Electromechanical Properties Of Dielectric Elastomers Subjected To Pre-Stressing, Liang Jiang, Tony Betts, David Kennedy, Stephen Jerrams

Articles

Dielectric elastomers (DEs) are being exploited for biological applications such as artificial blood pumps, biomi-metic grippers and biomimetic robots. Generally, polyacrylate and silicone rubber (SR)are the most widely use materials for fabricating DEsinterms of mixing with other polymers or compounding them with highly dielectric particles. Furthermore, pre-stretch offers an effective approach to increasing actuated strain and dielectric strength and eliminating pull-ininstability.

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In Vitro Evaluation Of The Cytotoxicity Of A Folate-Modified Β-Cyclodextrin As A New Anti-Cancer Drug Delivery System, Zlata Tofzikovskaya, Alan Casey, Orla L. Howe, Christine O'Connor, Mary Mcnamara

Articles

Many chemotherapeutic drugs are therapeutically non-selective and do not distinguish between healthy cells and tumour cells which can result in severe side effects and toxicity. Drug delivery systems can be used to target specific cells and therefore may eliminate many of the side effects, increasing drug efficiency and efficacy, and controlling drug release. One possible strategy for targeted drug delivery is to use unique molecular markers such as folate receptors in cancer cells. In this work the cytotoxicity of a novel cyclodextrin-folate conjugate, 6-deoxy-6-[(1-(-2amino)ethylamino)folate-β-cyclodextrin (CDEnFA) was studied using the MTT assay and the MCF-7 (Breast), HeLa (Cervical), A549 (Lung cancer) …

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Intelligent Text Classification System Based On Self-Administered Ontology, Manoj Manuja, Deepak Garg

Turkish Journal of Electrical Engineering and Computer Sciences

Over the last couple of decades, web classification has gradually transitioned from a syntax- to semantic-centered approach that classifies the text based on domain ontologies. These ontologies are either built manually or populated automatically using machine learning techniques. A prerequisite condition to build such systems is the availability of ontology, which may be either full-fledged domain ontology or a seed ontology that can be enriched automatically. This is a dependency condition for any given semantics-based text classification system. We share the details of a proof of concept of a web classification system that is self-governed in terms of ontology population …

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Counterculture, Ju-Jitsu And Emancipation Of Wood, Marcin Wójcik

Conference papers

This paper formulates a notion of material-oriented design in wood, proposing an alternative ontology where the material is seen as an equal rights partner to the designer. Further, I contrast the constructivist and evolutionary types of management, where in the latter systems are produced with minimal waste and energy expense. I discuss the implications of the approach on an example of five experimental projects, including my own in more detail. I advance that material-oriented design challenges the established form-matter relationship, design process, our understanding of authorship and bears an environmentally friendly potential.

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An Architectural Perspective On Structured Sacred Space—Recent Evidence From Iron Age Ireland, Frank Prendergast

Book/Book Chapter

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Full-Text Articles in Entire DC Network

Open Access Publications

Carpal Tunnel Syndrome And Computer Exposure At Work In Two Large Complementary Cohorts, Z. Mediouni, J. Bodin, Ann Marie Dale, E. Herquelot, M. Carton, A. Leclerc, N. Fouquet, C. Dumontier, Y. Roquelaure, Bradley A. Evanoff, A. Descatha

Open Access Publications

Evaluation Of Genetic Susceptibility Of Common Variants In Cacna1d With Schizophrenia In Han Chinese, Fanglin Guan, Lu Li, Chuchu Qiao, Gang Chen, Tinglin Yan, Tao Li, Tianxiao Zhang, Xinshe Liu

Open Access Publications

Impact Of Vitamin D Supplementation On Adiposity In African-Americans, P D. Chandler, J B. Scott, B F. Drake, K Ng, A T. Chan, B W. Hollis, K M. Emmons, E L. Giovannucci, C S. Fuchs, G G. Bennett

Open Access Publications

Somatic Chromosomal Translocation Between Ewsr1 And Fli1 Loci Leads To Dilated Cardiomyopathy In A Mouse Model, Miwa Tanaka, Shuichi Yamaguchi, Yukari Yamazaki, Hideyuki Kinoshita, Koichiro Kuwahara, Kazuwa Nakao, Patrick Y. Jay, Tetsuo Noda, Takuro Nakamura

Open Access Publications

The Role Of Conduct Disorder In The Relationship Between Alcohol, Nicotine And Cannabis Use Disorders, J. D. Grant, M. T. Lynskey, P. A. F. Madden, E. C. Nelson, L. R. Few, K. K. Bucholz, D. J. Statham, N. G. Martin, A. C. Heath, A. Agrawal

Open Access Publications

Higher Throughput Quantification Of Neutralizing Antibody To Herpes Simplex Viruses, Tamara P. Blevins, Michelle C. Mitchell, Maria Korom, Hong Wang, Yinyi Yu, Lynda A. Morrison, Robert B. Belshe

Open Access Publications

Open Access Publications

Open Access Publications

Cralbp Supports The Mammalian Retinal Visual Cycle And Cone Vision, Yunlu Xue, Susan Q. Shen, Jonathan Jui, Alan C. Rupp, Leah C. Byrne, Samer Hattar, John G. Flannery, Joseph C. Corbo, Vladimir J. Kefalov

Open Access Publications

Physical Activity Affects Brain Integrity In Hiv+ Individuals, Mario Ortega, Laurie M. Baker, Florin Vaida, Robert Paul, Brian Basco, Beau M. Ances

Open Access Publications

Sexual Selection And Cancer Biology, Joshua B. Rubin

Open Access Publications

An Intrinsic Case Study Into The Appropriateness Of A Bespoke Training Model As An Approach To Supporting The Postgraduate Demonstrator In Developing Pedagogical Skills Suitable For Undergraduate Scientific Laboratories., Barry Ryan

Theses

“The Relationship Between Approaches To Learning And Assessment Outcomes In Undergraduate Optometry Students”, Linda Moore

Theses

Nanotechnology Solutions For Global Water Challenges, Aine Whelan, Niall B. Mcguinness, Mary Garvey, Honey John, Chun Zao, Geshan Zhang, Dionysios D. Dionysiou, J. Anthony Byrne, Suresh C. Pillai

Books/Book chapters

Binding Of Dna By A Dinitro-Diester Calix[4]Arene: Denaturation And Condensation Of Dna, Mary Deasy, Pilar Lopez-Cornejo, F J. Ostos, J A. Lebron, M L. Moya

Articles

Critical Race Theory: A Strategy For Framing Discussions Around Social Justice And Democratic Education, Wesley Crichlow

Stream 2: Curriculum

Time Zones, Game Start Times, And Team Performance: Evidence From The Nba, Andrew Nutting, Joseph Price

Economics Faculty Research and Scholarship

Moving Beyond Causes: Optimality Models And Scientific Explanation, Collin Rice

Philosophy Faculty Research and Scholarship

Autonomous Statistical Explanations And Natural Selection, André Ariew, Collin Rice, Yasha Rohwer

Philosophy Faculty Research and Scholarship

Clinical Encounters With Immigrants: What Matters For U.S. Psychiatrists., Carolina Hausmann-Stabile, Peter J. Guarnaccia

Graduate School of Social Work and Social Research Faculty Research and Scholarship

Cherokee Freedmen And The Color Of Belonging, Lolita Buckner Inniss

Law Faculty Articles and Essays

The Green Chemistry And Filipino Approach To High School Experiments In Saint Paul College Pasig, Ronald G. Santos, Armando M. Guidote Jr

Chemistry Faculty Publications

Ecological Perspectives And Children’S Use Of The Internet: Exploring Micro To Macro Level Analysis, Brian O'Neill

Articles

Raman Micro-Spectroscopy For Rapid Screening Of Oral Squamous Cell Carcinoma, Luis Felipe Carvalho, Franck Bonnier, Kate O'Callaghan, Jeff O'Sullivan, Stephen Flint, Hugh Byrne, Fiona Lyng

Articles

Investigation Into The Electromechanical Properties Of Dielectric Elastomers Subjected To Pre-Stressing, Liang Jiang, Tony Betts, David Kennedy, Stephen Jerrams

Articles

In Vitro Evaluation Of The Cytotoxicity Of A Folate-Modified Β-Cyclodextrin As A New Anti-Cancer Drug Delivery System, Zlata Tofzikovskaya, Alan Casey, Orla L. Howe, Christine O'Connor, Mary Mcnamara

Articles

Intelligent Text Classification System Based On Self-Administered Ontology, Manoj Manuja, Deepak Garg

Turkish Journal of Electrical Engineering and Computer Sciences

Counterculture, Ju-Jitsu And Emancipation Of Wood, Marcin Wójcik

Conference papers

An Architectural Perspective On Structured Sacred Space—Recent Evidence From Iron Age Ireland, Frank Prendergast

Book/Book Chapter