Digital Commons Network^™

Principles Of Using Cold Atmospheric Plasma Stimulated Media For Cancer Treatment, Dayun Yan, Annie Talbot, Niki Nourmohammadi, Xiaoqian Cheng, Jerome Canady, Jonathan H. Sherman, Michael Keidar

Neurological Surgery Faculty Publications

To date, the significant anti-cancer capacity of cold atmospheric plasma (CAP) on dozens of cancer cell lines has been demonstrated in vitro and in mice models. Conventionally, CAP was directly applied to irradiate cancer cells or tumor tissue. Over past three years, the CAP irradiated media was also found to kill cancer cells as effectively as the direct CAP treatment. As a novel strategy, using the CAP stimulated (CAPs) media has become a promising anti-cancer tool. In this study, we demonstrated several principles to optimize the anti-cancer capacity of the CAPs media on glioblastoma cells and breast cancer cells. Specifically, …

Investigation Of Sex Differences In The Expression Of Rora And Its Transcriptional Targets In The Brain As A Potential Contributor To The Sex Bias In Autism, Valerie Wailin Hu, Tewarit Sarachana, Rachel M. Sherrard, Kristen M. Kocher

Biochemistry and Molecular Medicine Faculty Publications

Background

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by significant impairment in reciprocal social interactions and communication coupled with stereotyped, repetitive behaviors and restricted interests. Although genomic and functional studies are beginning to reveal some of the genetic complexity and underlying pathobiology of ASD, the consistently reported male bias of ASD remains an enigma. We have recently proposed that retinoic acid-related orphan receptor alpha (RORA), which is reduced in the brain and lymphoblastoid cell lines of multiple cohorts of individuals with ASD and oppositely regulated by male and female hormones, might contribute to the sex bias …

Bioxpress: An Integrated Rna-Seq-Derived Gene Expression Database For Pan-Cancer Analysis., Quan Wan, Hayley Dingerdissen, Yu Fan, Naila Gulzar, Yang Pan, Tsung-Jung Wu, Cheng Yan, Haichen Zhang, Raja Mazumder

Biochemistry and Molecular Medicine Faculty Publications

BioXpress is a gene expression and cancer association database in which the expression levels are mapped to genes using RNA-seq data obtained from The Cancer Genome Atlas, International Cancer Genome Consortium, Expression Atlas and publications. The BioXpress database includes expression data from 64 cancer types, 6361 patients and 17 469 genes with 9513 of the genes displaying differential expression between tumor and normal samples. In addition to data directly retrieved from RNA-seq data repositories, manual biocuration of publications supplements the available cancer association annotations in the database. All cancer types are mapped to Disease Ontology terms to facilitate a uniform …

Proteomic Profiling Of High Risk Medulloblastoma Reveals Functional Biology, Jerome A. Staal, Ling San Lau, Huizhen Zhang, Wendy J. Ingram, Andrew R. Hallahan, Roger J. Packer, Brian R. Rood, Kristy J. Brown, +6 Additional Authors

Neurology Faculty Publications

Genomic characterization of medulloblastoma has improved molecular risk classification but struggles to define functional biological processes, particularly for the most aggressive subgroups. We present here a novel proteomic approach to this problem using a reference library of stable isotope labeled medulloblastoma-specific proteins as a spike-in standard for accurate quantification of the tumor proteome. Utilizing high-resolution mass spectrometry, we quantified the tumor proteome of group 3 medulloblastoma cells and demonstrate that high-risk MYC amplified tumors can be segregated based on protein expression patterns. We cross-validated the differentially expressed protein candidates using an independent transcriptomic data set and further confirmed them in …

Designing A Rotary Vegetation System, Azita Amiri

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Learning, Memory And Cognitive Studies In A Mouse Model Of Tyrosinemia Type I, Gordon Macgregor

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

"In An Earlier Study (Bono Et Al., 20111 Pnas) My Lab Has Examined The Gene Expression Changes Occuring In The Lower Reproductive Tract Of The Female Drosophila Mojavensis (Cactophilic Fruit Flies) Immediately Following Copulation", Luciano M. Matzkin

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

The Role Of Gastrointestinal Flora And Probiotics In Normal Gi Physiology And Disease, Gordon Macgregor

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

The Cactophillic Drosophillia Mojavensis Feed On The Yeast And Bacteria That Grow In Necrotic Cactus Tissues, Luciano M. Matzkin

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

"The Mendenhall Lab Uses Genetic Engineering To Determine How Our Geonome Regulates Or Turns Genes On Or Off In Certain Tissue Or Cell Types", Eric M. Mendenhall

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Interdisciplinary Research With Nursing And Biology: Identification Of Effective Disinfectants On Microbial Growth, Pam O'Neal, Joseph Leahy

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Interdisciplinary Research With Nursing Biology: Identification Of Microbial Growth In Blue Bulb Suction Devices, Pam O'Neal, Joseph Leahy

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

"The Project Will Be Part Of A Larger, On-Going Study Describing The Reproductive Schedule Of Several Species Of Cyprinid ("Carp-Like") Fishes In The Flint River East Of Huntsville", Bruce Stallsmith

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

"This Rceu Project Aims At Studying The Feasibility Of Using Bamboo Fiber As An Alternative To Synthetic Fibers To Reinforce Composite Materials For Civil Structure Applications", Hongyu Zhou

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Narrative Therapy, Robert H. Rice

Nursing Faculty/Staff Publications

Narrative therapy (NT) is a strengths-based approach to psychotherapy that uses collaboration between the client or family and the therapist to help clients see themselves as empowered and capable of living the way they want. In the face of crisis or trauma, NT helps clients achieve a “This too will pass” attitude, while positioning the therapist as an appreciative ally in the process. NT is useful with individuals and is used extensively with families due to its ability to separate clients from problems and unite families against problematic patterns. NT also lends itself well to joining with families because it …

Development And Validation Of A Robust, Adjustable Hippotherapy Simulator, Melissa Montgomery

Graduate Theses - Biology & Biomedical Engineering

This thesis describes all aspects of development, testing, refinement, and validation of a robust, adjustable hippotherapy simulator. This simulator primarily focuses on physical therapy; however, emotional benefits can be realized. It uniquely innovates on an effective design that has only partially been addressed in other simulators. Using a variable drive for adjustable speed, it incorporates reinforcements to increase load capacity along with removable camshafts that adjust the throw heights in the device’s simulated hips and shoulders. For testing and validation, Qualisys software and motion capture supported analysis of the device’s motion paths and speeds. Riders weighing approximately 135-300 pounds successfully …

Applying Anthropology To What? Tactical/Ethical Decisions In An Age Of Global Neoliberal Imperialism, James R. Veteto, Joshua Lockyer

Faculty Publications - Behavioral Sciences

This article introduces the Journal of Political Ecology Special Section on ‘towards a political ecology of applied anthropology.’ We provide a brief overview and analysis of the history and application of applied and practicing anthropology. Examining moral and ethical issues related to the application of anthropology, we assess current endeavors and make suggestions for future directions from a political ecology perspective. Introducing five articles that exemplify our approach, we identify common themes and particular contexts that both unify and distinguish each of the contributions. Throughout this introduction, we propose a potential guidepost for a political-ecology informed applied anthropology: any applied …

Unraveled Winter 2015, Southern Adventist University

Unraveled - School of Education and Psychology Newsletter

The Winter 2015 issue of Unraveled features articles on the new B.S. psychology degree in family systems, a pictorial directory of the 2015 education and psychology graduates, and an alumni spotlight.

Operationalizing Resilience For Adaptive Coral Reef Management Under Global Environmental Change, Kenneth R. N. Anthony, Paul A. Marshall, Ameer Abdulla, Roger Beeden, Christopher Bergh, Ryan Black, C. Mark Eakin, Edward T. Game, Margaret Gooch, Nicholas A. J. Graham, Alison Green, Scott F. Heron, Ruben Van Hooidonk, Cheryl Knowland, Sangeeta Mangubhai, Nadine Marshall, Jeffrey A. Maynard, Peter Mcginnity, Elizabeth Mcleod, Peter J. Mumby, Magnus Nystrom, David Obura, Jamie Oliver, Hugh P. Possingham, Robert L. Pressey, Gwilym Rowlands, Jerker Tamelander, David Wachenfeld, Stephanie Wear

HCAS Student Articles

Cumulative pressures from global climate and ocean change combined with multiple regional and local-scale stressors pose fundamental challenges to coral reef managers worldwide. Understanding how cumulative stressors affect coral reef vulnerability is critical for successful reef conservation now and in the future. In this review, we present the case that strategically managing for increased ecological resilience (capacity for stress resistance and recovery) can reduce coral reef vulnerability (risk of net decline) up to a point. Specifically, we propose an operational framework for identifying effective management levers to enhance resilience and support management decisions that reduce reef vulnerability. Building on a …

Field To Fork Farm: Resilience Through Diversification, Ravdeep Jaidka

The Sustainability Institute Publications

No abstract provided.

Wolfe’S Neck Farm: Resilience Through Soil Regeneration, Ravdeep Jaidka

The Sustainability Institute Publications

No abstract provided.

Individual Case Study: The Sos Approach To Feeding, Amy Dow

Occupational Therapy Program Student Theses, Dissertations and Capstones

Capstone Paper:

Individual Case Study: The SOS Approach to Feeding

Cag Repeat Length And Suicidality In Huntington's Disease, Christen Kutz

Health Sciences Program Student Theses, Dissertations and Capstones

Abstract: The purpose of this study was to determine if a correlation exists between suicide and CAG repeat length in Huntington’s disease. Methodology: A case-control study using the COHORT Study de-identified database was conducted. Responses were collected from 163 participants. Depression, substance abuse history and use of benzodiazepines were covariates. Responses to the UHDRS behavioral section pertaining to the frequency and severity of suicidal ideation (“feels life is not worth living”, “has suicidal thoughts”) were analyzed. Results: Despite taking depression, benzodiazepine use, and history of substance abuse into account, there was a predictive relationship between CAG repeat length and frequency …

Effects Of Foster Care Placements On The Mental Health Of Abused Children In Florida, Sarah M. Nelson

Theses and Dissertations

INTRODUCTION: As evidenced in the literature, when maltreated children are admitted into state care, they are frequently not afforded sufficient mental health treatment. Concomitantly, foster parents are often not given proper training in providing complex care for these children. As such, the current study aimed to examine the role that foster care has in the development of psychopathology in maltreated children and their caregivers. METHODS: Participants included 234 maltreated youths (ages 7 to 17) presenting for treatment at a community mental health center specializing in childhood trauma. Children and adolescents currently residing in foster care as well as in their …

Cardiovascular Reactivity In Posttraumatic Stress Disorder And Depression, Lydia R. Malcolm

Theses and Dissertations

Exaggerated cardiovascular reactivity (CVR) to stress has been implicated in the increased risk for cardiovascular disease (CVD) in individuals with posttraumatic stress disorder (PTSD), yet mixed results have been reported. The CVR research may have been confounded by underrepresentation of women, few studies using sophisticated cardiovascular measurement, and a lack of analyses of PTSD symptom clusters. The purpose of the present study was to examine if young civilian women (M ± SD = 29.89±7.33) with PTSD (n=17) demonstrate greater CVR than women with depression (n=12) or no mental illness controls (n=18), and to explore the relationships between CVR and PTSD …

Factors Predicting Return To Play In Sports-Related Concussion: An Empirical Evaluation, Douglas R. Polster

Theses and Dissertations

Sports-related concussion and its subsequent management have become a top priority within the sports medicine research spectrum. In order to properly understand the complex nature of concussion management, multiple aspects of the injury were explored including the psychobiological nature of the injury, risk for further injury, diagnostic concerns, and return to play decision making. While much research has been dedicated to these areas, one in particular, return to play, is the focus of this current research study. To date, there has not been a method for accurately predicting return to play time after an athlete has sustained sports-related concussion. In …

The Lived Experiences Of Adult Children Of Mid To Later-Life Parental Divorce: An Interpretative Phenomenological Analysis, Joan Collins Ricketts

Department of Family Therapy Dissertations and Applied Clinical Projects

This study examined the lived experiences of adult children of mid-later life parental divorce. It was designed and conducted to address the gap in the current literature regarding this phenomenon. The experiences of 5 Adult Children of Divorce (ACD) ages 25 to 45, who experienced mid-later life parental divorce, were examined using in-depth semi-structured interviews. The researcher employed an interpretive phenomenological analysis (IPA) of which the findings illustrated various outcomes for adults experiencing their parents’ mid-later life divorce. The results of this study showed that parents’ waiting until the children are “grown” does not mitigate potentially detrimental outcomes for these …

Cultural Resources Surveys Conducted During December 2014 Central Eagle Ford Zone Gonzales, De Witt, Karnes, And Wilson Counties, Reign Clark, Scott Justen, Ron Ralph

Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State

During the month of December 2014, Goshawk Environmental Consulting, Inc. (Goshawk) conducted two cultural resources surveys within the Eagle Ford Play, Central Eagle Ford Zone at the request of EOG Resources, Inc. (EOG). The two project areas subjected to cultural resources investigations included the proposed Ginobili-Leonard Gathering Pipeline and HB Unit #1H, #2H, and #3H Access Road. Except where noted, each Area of Potential Effect (APE) was a 75-foot (23-meter [m]) wide Right-of-Way (ROW) consisting of a 50-foot (15-m) wide permanent easement and a 25-foot (8-m) wide temporary construction easement. Investigations were conducted by Goshawk archeologists Reign Clark and Scott …

Cultural Resources Surveys Conducted During December 2014 South Eagle Ford Zone Atascosa, La Salle, And Mcmullen Counties, Scott Justen, Reign Clark, Ron Ralph

Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State

During the month of December 2014, Goshawk Environmental Consulting, Inc. (Goshawk) conducted seven cultural resources surveys within the Eagle Ford Play, South Eagle Ford Zone, at the request of EOG Resources, Inc. (EOG). The seven project areas subjected to cultural resources investigations included the proposed Cashen to Pena-Butts Gathering Pipeline, Quail to Quail A Gathering Pipeline, Dall to Warthog Gathering Pipeline, Tangerine Unit Gathering Pipeline, Cuellar Unit #7H and #8H Access Road, Galaxy Unit #1H Access Road, and Quail Unit #11 Flowline. Except where noted, each Area of Potential Effect (APE) was a 75-foot (23-meter [m]) wide Right-of-Way (ROW) consisting …

Supplemental Intensive Archaeological Survey For The Proposed Los Vientos Iv Wind Energy Project, Brandon Richards

Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State

On February 19 and 25, 2015, Energy Renewal Partners, LLC (Energy Renewal) carried out an intensive pedestrian survey on a proposed portion of the Los Vientos IV Wind Energy Project site located on Texas General Land Office (GLO) land. Brandon Richards served as the Principal Investigator, and was aided by Jennifer Klingshirn. The survey area (“Project Area,” Area of Potential Effect, or “APE”) consisted of approximately 4.1 acres of upland mesquite pasture, about 10 miles (16 km) northeast of Rio Grande City, in Starr County, Texas. The purpose of the intensive survey was to supplement the 126 acres surveyed in …