Digital Commons Network^™

Communities Of Innovation, Michael Mattioli

Northwestern University Law Review

No abstract provided.

Synthetic Approaches To The Understanding Of Dna Nucleobase Methylation, Jagruti Rana

Dissertations

DNA methylation is a major source of genetic variation and cancer. Methylation occurs when nucleophilic DNA bases react with methylating agent methyl methanesulfonate (MMS), dimethyl sulfate (DMS), N-methyl-N-nitrosourea (MNU), N-methyl-N-nitro-N-nitrosoguanidine (MNNG), etc. N7-methyl-2'-deoxyguanosine (N7-methyl-dG, or ^7MedG) adduct is the most abundant DNA methylation products for most methylating agents. DNA polymerase actions on ^7MedG are difficult to study due to its instability against ring- opening hydrolysis and deglycosyl ati on. Oligonucleotides containing a single chemical adduct of ^7MedG cannot be chemically synthesized. In addition, ^7MedG is unstable in vivo …

Monitoring Of Cerebellar Injury Using Micro Ecog Signals In Ketamine/Xylazine Treated Rats, Gokhan Ordek

Dissertations

Much of the cerebellar research has been conducted in anesthetized animals, particularly using ketamine/xylazine combination in rats, and yet the absolute impact of the anesthesia on the neural circuit remains unanswered . In the current study, spontaneous electrical activity and sensory evoked potentials from the cerebellar surface with chronically implanted, flexible-substrate, multielectrode arrays in rats were collected and analyzed with the motor cortex signals. The power spectra and the intercontact coherence plots of the spontaneous activity in the awake-quiet animals extended up to 800 Hz in the cerebellum and only up to 200 Hz in the motor cortex. Ketamine/xylazine anesthesia …

E Pluribus Unum: What Individual Whales Can Tell Us About Enigmatic Species Distribution And Social Organization, Tanya Marie Lubansky

Dissertations

Large whales have historically been difficult to study and many aspects of their ecology remain unknown especially at the long -term population level. The ability to identify individual whales based on natural markings provides the opportunity to track individuals over time and space; this data may offer more insight into the ecology of whales than previously imagined. This study demonstrates use of photo-identification data to model both social structure and habitat selection, minimizing the need for invasive research and greatly increasing the sample size used in such endeavors. A conditional logistic model is written for a 20-year sightings dataset on …

Developing An Insulin Producing Tissue Using Mouse Embryonic Stem Cells, Neha Mahendrakumar Jain

Dissertations

This thesis describes derivation of pancreatic insulin producing cells (IPCs) from mouse embryonic stem cells and development of three-dimensional (3D) engineered tissue system to provide physiologic culture conditions for IPCs. Upon using a previously established protocol, IPCs have been successfully derived from mouse embryonic stem cells and characterized in vitro . IPCs not only express classical markers of pancreatic beta cells but also exhibit glucose responsive behavior. Interestingly while deriving IPCs from mouse embryonic stem cells, islet endothelial cells have also been identified and successfully isolated from the culture. Derivation of a pure population of endothelial cells expressing specific markers …

The University Of San Francisco Fact Book And Almanac 2015, Alan Ziajka

USF Fact Book and Almanac

No abstract provided.

Inkjet Printing Multifunctional Chromatic Sensors And Chromism Study, Aide Wu

Dissertations

The thermochromism and chemochromism of polydiacetylene (PDAs) and PDA/ZnO nano composites have been systematically studied by attentuated total reflection (ATR)- Fourier transform infrared (FTIR), temperature-dependent Raman, colorimetric (using optical densitometry) and differential scanning calorimetry (DSC). Reversibility of PDAs has been enhanced by the formation of chelation between the carboxylic groups on side chain of diacetylene and Zn ion. The thermochromatic transition temperature increases with the concentration of ZnO.

Thin films of polydiacetylene (PDAs) and PDA/ZnO nanocomposites have been successfully fabricated by inkjet printing both solution type and suspension type ink. Results suggest that PDA monomers are well-aligned and closely packed …

Spartan Daily, January 31, 1940, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 28, Issue 77

Polymeric Nitrogen By Plasma Enhanced Chemical Vapor Deposition, El Mostafa Benchafia

Dissertations

With the urgent need for new environmentally-friendly energetic materials, the field of polymeric nitrogen, predicted to be a high energy density energetic, is now at a critical stage in its development. In spite of extensive first principles calculations regarding the existence and stability of different polymeric nitrogen structures, their successful syntheses have been rare. This dissertation describes the first detailed study of a plasma-enhanced chemical vapor deposition (PECVD) approach to the synthesis of polymeric nitrogen. PECVD provides non-equilibrium conditions known to produce high pressure-temperature phases. Molecular nitrogen mixed with hydrogen and argon is used as the gas phase precursor to …

Admissions Report - Detailed Data - January 2015, Office Of Institutional Research & Effectiveness, Wright State University

Admissions Reports

Detailed report of applicants to Wright State including data on county of residency, intended major, and ethnicity for Fall Semester 2015.

Fates Of Spilt Oil And Factors Affecting The Bio-Degradation Of Oil: A Review, Amogh-Ranganath Chakravarthy

Theses

The usage of crude oil and its products is increasing; in turn, the number of spills is also going up. The inland spills are the more recurrent spills in the U.S today. This review article deals with the weathering of oils, which commences just after oil spills into the environment with various processes such as evaporation, dissolution, photo-oxidation, dispersion, emulsification and bio-degradation along with other possible fates. Biodegradation is one of the most significant processes of weathering which depends on oil physical and chemical characteristics, environmental characteristics, pH, salinity and oil concentration. There is a range of oil concentration for …

The Logging Ban Policy In Addressing Deforestation: A Comparison Between Thailand And Indonesia, Safrina Safrina

Indonesian Journal of International Law

The logging ban policy is applying in several countries, such as Thailand and Indonesia, in order to deal with deforestation and forest degradation in natural forests. However, both countries still have had difficulties resolving the problem. The logging ban in Thailand does not work as expected due to centralized systems of forestry policy that still applies in Thailand. However, Indonesia is actively adjusting the decentralized system, which gives authority to local governments to set policies regarding forestry. The effectiveness of logging ban to achieve conservation goals and economic development continues to be debated; however, it should be noted that the …

Marz: An Algorithm To Combinatorially Analyze Gapped N-Mer Models Of Transcription Factor Binding, Rowan G. Zellers, Robert A. Drewell, Jacqueline M. Dresch

Biology

Background: A key challenge in understanding the molecular mechanisms that control gene regulation is the characterization of the specificity with which transcription factor proteins bind to specific DNA sequences. A number of computational approaches have been developed to examine these interactions, including simple mononucleotide and dinucleotide position weight matrix models. Results: Here we develop a novel, unbiased computational algorithm, MARZ, that systematically analyzes all possible gapped matrices across a fixed number of nucleotides. In addition, to evaluate the ability of these matrix models to predict in vivo binding sites, we utilize a new scoring system and, in combination with established …

An Electrospinning Apparatus For The Production Of Heterogeneous Scaffolds And Their Application In Cartilage Regeneration, Andrew Ryan Hollingsworth

Theses

The human body contains a vast array of soft and hard tissues, each with their own unique set of physical, chemical, mechanical, and electrical properties. It is the combination of these tissues that allows the human body to function as it does. However, these tissues are subject to wear, fatigue, and injury and thus can potentially limit the functions of the body. Therefore, tissue engineering has sought various natural and synthetic materials that can be used for fabrication of cellular scaffolds that have the ability to promote cellular attachment, proliferation, differentiation, and eventual whole tissue formation for replacement and repair …

Study Protocol For Young & Strong: A Cluster Randomized Design To Increase Attention To Unique Issues Faced By Young Women With Newly Diagnosed Breast Cancer, Mary L. Greaney, Kim Sprunck-Harrild, Kathryn J. Ruddy, Jennifer Ligibel, William T. Barry, Emily Baker, Meghan Meyer, Karen M. Emmons, Ann H. Partridge

Kinesiology Faculty Publications

Background: Each year, approximately 11% of women diagnosed with breast cancer in the United States are 45 years of age or younger. These women have concerns specific to or accentuated by their age, including fertility-related concerns, and have higher rates of psychosocial distress than women diagnosed at older ages. Current guidelines recommend that fertility risks be considered early in all treatment plans; however, the extant research indicates that attention to fertility by the healthcare team is limited. Importantly, attention to fertility may be a proxy for whether or not other important issues warranting attention in younger women with breast cancer …

Design And Analysis Of Algorithms For Similarity Search Based On Intrinsic Dimension, Xiguo Ma

Dissertations

One of the most fundamental operations employed in data mining tasks such as classification, cluster analysis, and anomaly detection, is that of similarity search. It has been used in numerous fields of application such as multimedia, information retrieval, recommender systems and pattern recognition. Specifically, a similarity query aims to retrieve from the database the most similar objects to a query object, where the underlying similarity measure is usually expressed as a distance function.

The cost of processing similarity queries has been typically assessed in terms of the representational dimension of the data involved, that is, the number of features used …

Molecular Modeling Of Sigma 1 And Sigma 2 Receptor Ligands: Pharmacophore Development And Comparison Using Discotech And Bioactivity Prediction Comparison Of Ab Initio And Density Functional Comfa Studies For Spiro And Other Receptor Ligands, Lisa M. Kardos

Dissertations

The role of the biological receptor is currently being studied by researchers in medicine. Information about sigma receptors in particular can be gained by studying the ligands associated with each type, sigma 1 or sigma 2. Sigma 1 receptor ligands consist of drug candidates that often have psychiatric and neurological applications; sigma 2 receptor ligands consist of drug candidates that have been linked with cancer treatment among other applications.

Molecular modeling of biological receptor ligands often encompasses pharmacophore development and Comparative Molecular Field Analysis (CoMFA). Pharmacophore models are developed to understand the unique features such as binding groups that make …

Fem Of Electrospinning Compared To Inkjet Printing Model, Maikel Ghaly

Theses

Electrospinning is a process that uses electrostatic forces to produce nanofibers, or fibers in the nano scale. Nanofibers are widely used in many fields like drug delivery and tissue engineering. Nowadays, it is gaining much attention in the research community as an advantageous process. However, there are many parameters that controlnanofiber formation. This research intends to develop a model of electrospinning on the basis of an inkjet printer technique by using a computer aided simulation (COMSOL). Inkjet printing is a technique that delivers small volumes at high repetitions which can betransported by electrostatic forces through the air onto their intended …

Cancer Risk Prediction With Next Generation Sequencing Data Using Machine Learning, Nihir Patel

Theses

The use of computational biology for next generation sequencing (NGS) analysis is rapidly increasing in genomics research. However, the effectiveness of NGS data to predict disease abundance is yet unclear. This research investigates the problem in the whole exome NGS data of the chronic lymphocytic leukemia (CLL) available at dbGaP. Initially, raw reads from samples are aligned to the human reference genome using burrows wheeler aligner. From the samples, structural variants, namely, Single Nucleotide Polymorphism (SNP) and Insertion Deletion (INDEL) are identified and are filtered using SAMtools as well as with Genome Analyzer Tool Kit (GATK). Subsequently, the variants are …

Combustion Dynamics Of Metal Powders In Mixed Gas Flows, Amy Lee Corcoran

Theses

Predictive mechanisms for particle ignition and combustion rates are required in order to develop optimized propellant and energetic formulations using micron-sized metal powders, such as aluminum and magnesium. Most current descriptions are based on laboratory experiments performed in stationary or laminar combustion configurations using pure metals burned in single oxidizers. However, practical configurations take into account different metals, including alloys, that burn in various oxidizing environments and various flow conditions. Validity of the present descriptions for such environments has not been established. This experimental study is aimed to measure burn times for aluminum, magnesium, and mechanically alloyed Al-Mg particles burning …

Improving Project Success In An Online Mathematics Course, David Shoenthal

Journal of Humanistic Mathematics

With more mathematics courses migrating to online environments, it is important to know whether these courses are comparable to their face-to-face counterparts. To that end, in two different years, I taught an online and a face-to-face section of the same finite mathematics course. After analyzing the data regarding differences in the two sections for the first year, I incorporated changes intended to improve the consistency of project success between the two sections as well as the overall success of the class projects in the online section. My main tool was mimicking the interaction of group members and providing immediate instructor …

Love Games: A Game-Theory Approach To Compatibility, Kerstin Bever, Julie Rowlett

Journal of Humanistic Mathematics

In this note, we present a compatibility test with a rigorous mathematical foundation in game theory. The test must be taken separately by both partners, making it difficult for either partner alone to control the outcome. To introduce basic notions of game theory we investigate a scene from the film "A Beautiful Mind" based on John Nash's life and Nobel-prize-winning theorem. We recall this result and reveal the mathematics behind our test. Readers may customize and modify the test for more accurate results or to evaluate interpersonal relationships in other settings, not only romantic. Finally, we apply Dyson's and Press's …

On The Persistence And Attrition Of Women In Mathematics, Katrina Piatek-Jimenez

Journal of Humanistic Mathematics

The purpose of this study was to investigate what motivates women to choose mathematics as an undergraduate major and to further explore what shapes their future career goals, paying particular attention to their undergraduate experiences and their perceptions of the role of gender in these decisions. A series of semi-structured, individual interviews were conducted with twelve undergraduate women mathematics majors who were attending either a large public university or a small liberal arts college. This study found that strong mathematical identities and enjoyment of mathematics heavily influenced their decisions to major in mathematics. At the career selection stage, these women …

From Attorney To Detective: Investigative Web Research, Carol A. Watson

Continuing Legal Education Presentations

As a lawyer, it’s not unusual to be called upon to help a client with personal investigation matters. You might find yourself needing to provide advice on topics ranging from whether a businessman is legitimate to assisting with a search for missing heirs. Since everything is on the internet now that should be a simple task, but it may not be as simple as it seems. If you’ve got the time, you can usually find much investigative information on the web such as criminal records, business records, property ownership, and professional licenses, but you’ll have to be thorough, patient and …

Beyond The Law: Connecting With Expertise In Other Fields, Suzanne R. Graham

Continuing Legal Education Presentations

For a variety of reasons, law school graduates might find themselves in need of advanced degrees or continuing education in other disciplines. The how-to and where of navigating to the best, most-current resources and continuing education opportunities in fields beyond the law might be less obvious. The following tips are to provide basic, but vetted, resources for pursuing continuing education in areas outside of the law. Professionals can and should consult with experts in other fields. There is no quick and easy substitute for years of in depth study reinforced by practical application. However, retooling is a reality and the …

You're Trans-Mexi-Fying Right Before Our Eyes: Westernized Bodily Features And Beauty Practices In Ugly Betty, Luz-Maria Tato-Pazo

Journal of International Women's Studies

Makeover narratives are a form of discourse which relies on some type of transformation as a path to success. These narratives mainly target the bodies of white middle-class and middle-aged heterosexual women with the aim of creating more conventionally beautiful feminine subjects. This article explores the beauty practices and rituals present in the US dramedy Ugly Betty. We look in detail at makeover narratives and their close association with contemporary idealized versions of female attractiveness. Closely tied up with the makeover canon, the beauty industry entails processes of disciplining women’s bodies to meet the requirements of an ideal feminine …

Gender And Water In Northeast Thailand: Inequalities And Women's Realities, Sari Andajani-Sutjahjo, Siriporn Chirawatkul, Erico Saito

Journal of International Women's Studies

The water world is socially constructed, reflecting continuous global gender inequalities and discrimination by those who hold dominant perspectives on water. While there is a strong global acknowledgement of the roles of women in water management by the United Nations International Water for Life Decade 2005-2015, discourses on gender mainstreaming in water management are still marginalised and under-theorised. The Millennium Development Goal-7 on environmental sustainability, addressing the need of more than one billion people for a significant improvement to accessing safe drinking water and basic sanitation, stagnated without a strong political will to include gender ideology in mainstream water perspectives. …

Natural Woman, Unnatural Mother: The Convergence Of Motherhood And The "Natural" World In Alice Walker’S Meridian, Sampada Chavan

Journal of International Women's Studies

Many cultures around the world equate being womanly to being motherly. However, all women are not physically or psychologically equipped to handle motherhood. What happens to these women who are burdened with motherhood and are unable to deal with it? Alice Walker’s protagonist in her novel Meridian is an otherwise accomplished woman, but she fumbles with the notion of ideal woman-ness. Cultural conventions also dictate that women are closer to nature and that motherhood is a “natural” and expected outcome in a woman’s life. While Meridian is close to nature, she has no interest in motherhood. This duality in her …

Ecofeminism And Natural Disasters: Sri Lankan Women Post-Tsunami, Alyssa Banford, Cameron Kiely Froude

Journal of International Women's Studies

Women experience a host of negative consequences during and after a natural disaster. A variety of feminist theories have been used to explore this phenomenon. The aim of this paper is to posit the need for an ecofeminist perspective on analyzing women’s vulnerabilities post-natural disaster. The authors will discuss the history and branches of ecofeminism, highlighting their utility in exploring the intersection of race, class, and gender in the aftermath of disaster. An ecofeminist analysis of Sri Lankan women’s vulnerability in the wake of the 2004 tsunami will be used to illustrate the utility of the theory. Implications of using …

2015-01 Library Impact Statement For Avs/Pls 275 Pasture And Grazing Management In Sustainable Agriculture, Michael Cerbo

Library Impact Statements

Library Impact Statement submitted in response to new course proposal for AVS/PLS 275 Pasture and Grazing Management in Sustainable Agriculture. This course was supported with no need for additional resources.