Digital Commons Network^™

Jižní Město As A Place To Live From The Perspective Of Two Generations Of Its First Inhabitants, Jana Barvíková

Economic and Business Review

The paper introduces the results of a qualitative analysis of in-depth interviews with respondents in their thirties (who as children at the age of 2-3 moved with their parents into the Prague housing estate Jižní Město in 1977-1978 and spent their childhood and adolescence there) and with their parents. The dataset allows for the identification and analysis of phenomena and processes that are typical of housing estates and life in housing estates during the last thirty years in the context of society changes and maturing of the estates.

Students Selected For Inaugural Career Immersion Excursion, Kim Hill

News and Events (Discontinued Series)

No abstract provided.

Kenny '13 Receives Top Graduate Award At Australian University, Kim Hill

News and Events (Discontinued Series)

No abstract provided.

Coordination Failure, Ishrat Husain Dr.

Faculty Research - Newspaper and Magazine Articles

Pakistan would be an excellent case study for anyone studying topics such as ‘perpetual confrontation and polarisation of all kinds’, ‘blame game’, ‘passing the buck’ and ‘don’t accept responsibility’. Recent examples of public squabbling include those of: electric power regulator Nepra and the water and power ministry; the Planning Commission and the two energy ministries; the Privatisation Commission and the Sindh government on the steel mills; the interior ministry and Sindh on the Rangers; and the tussle over CPEC routes as well as that related to the Nandipur project and LNG procurement.

Hot Spot Mutation In Tp53 (R248q) Causes Oncogenic Gain-Of-Function Phenotypes In A Breast Cancer Cell Line Derived From An African American Patient, Nataly Shtraizent, Hiroshi Matsui, Alla Polotskaia, Jill Bargonetti

Publications and Research

African American (AA) breast cancer patients often have triple negative breast cancer (TNBC) that contains mutations in the TP53 gene. The point mutations at amino acid residues R273 and R248 both result in oncogenic gain-of-function (GOF) phenotypes. Expression of mutant p53 (mtp53) R273H associates with increased cell elasticity, survival under serum deprivation conditions, and increased Poly (ADP ribose) polymerase 1 (PARP1) on the chromatin in the AA-derived TNBC breast cancer cell line MDA-MB-468. We hypothesized that GOF mtp53 R248Q expression could stimulate a similar phenotype in the AA-derived TNBC cell line HCC70. To test this hypothesis we depleted the R248Q …

Rna Sequencing Analysis Of The Msl2msl3, Crl, And Ggps1 Mutants Indicates That Diverse Sources Of Plastid Dysfunction Do Not Alter Leaf Morphology Through A Common Signaling Pathway, Darron R. Luesse, Margaret E. Wilson, Elizabeth S. Haswell

Biology Faculty Research

Determining whether individual genes function in the same or in different pathways is an important aspect of genetic analysis. As an alternative to the construction of higher-order mutants, we used contemporary expression profiling methods to perform pathway analysis on several Arabidopsis thaliana mutants, including the mscS-like (msl)2msl3 double mutant. MSL2 and MSL3 are implicated in plastid ion homeostasis, and msl2msl3 double mutants exhibit leaves with a lobed periphery, a rumpled surface, and disturbed mesophyll cell organization. Similar developmental phenotypes are also observed in other mutants with defects in a range of other chloroplast or mitochondrial functions, including …

Evaluating Different Distributed-Cyber-Infrastructure For Data And Compute Intensive Scientific Application, Arghya Kusum Das, Seung Jong Park, Jaeki Hong, Wooseok Chang

Computer Science Faculty Research & Creative Works

Scientists are increasingly using the current state of the art big data analytic software (e.g., Hadoop, Giraph, etc.) for their data-intensive applications over HPC environment. However, understanding and designing the hardware environment that these data- and compute-intensive applications require for good performance is challenging. With this motivation, we evaluated the performance of big data software over three different distributed-cyber-infrastructures, including a traditional HPC-cluster called SuperMikeII, a regular datacenter called SwatIII, and a novel MicroBrick-based hyperscale system called CeresII, using our own benchmark Parallel Genome Assembler (PGA). PGA is developed atop Hadoop and Giraph and serves as a good real-world example …

Formal Modeling And Verification Of Delay-Insensitive Circuits, Hoon Park

Dissertations and Theses

Einstein's relativity theory tells us that the notion of simultaneity can only be approximated for events distributed over space. As a result, the use of asynchronous techniques is unavoidable in systems larger than a certain physical size. Traditional design techniques that use global clocks face this barrier of scale already within the space of a modern microprocessor chip. The most common response by the chip industry for overcoming this barrier is to use Globally Asynchronous Locally Synchronous (GALS) design techniques. The circuits investigated in this thesis can be viewed as examples of GALS design. To make such designs trustworthy it …

Redescription And Lectotype Designation Of Vaejovis Lapidicola Stahnke, 1940 (Scorpiones: Vaejovidae), Matthew R. Graham

Euscorpius

The original description of the Arizona scorpion species Vaejovis lapidicola Stahnke, 1940 consists of a single paragraph. Furthermore, a holotype for this species was never designated. To remedy this, two syntypes of V. lapidicola were obtained for study. A male syntype is redescribed and designated the lectotype, and a female is assigned as a paralectotype. The taxonomic status of V. lapidicola is also confirmed.

Laterobasal Aculear Serrations (Las) In Scorpion Family Vaejovidae (Scorpiones: Chactoidea), Victor Fet, Michael E. Soleglad, Michael S. Brewer

Euscorpius

The discovery of a new structure on the laterobasal aspect of the telson aculeus is described here for the first time. This structure, termed the laterobasal aculear serrations (LAS), is a row of minute denticles located on each side of the aculeus base, found exclusively in scorpion family Vaejovidae, thus potentially providing a new synapomorphy for this New World family. The LAS structure of major representative vaejovid genera and Vaejovis groups is illustrated with SEM micrographs. Also provided is a comprehensive list of non-vaejovid Recent scorpion genera examined where the LAS structure was found to be absent.

The Effect Of Insularity On The Seasonal Population Structure Of Mesobuthus Gibbosus (Scorpiones: Buthidae), Dimitris Kaltsas, Iasmi Stathi, Moysis Mylonas

Euscorpius

We compared the population structure of Mesobuthus gibbosus from autumn to mid-summer at two similar phryganic ecosystems, one in continental Greece (Thessalia, near Volos city) and one in insular Greece (eastern Crete). Data were collected monthly using the capture-recapture method. At both sites, density was low during the cold period and increased towards summer. During the samplings, only a small percentage of each population was present. Population density and co-occurrence of scorpions with scorpions or other animals was higher in Crete than in Volos, probably due to the higher inter- and intraspecific competition in Volos. The population structure of the …

Development Of The Pebl Traveling Salesman Problem Computerized Testbed, Shane T. Mueller, Brandon S. Perelman, Yin Yin Tan, Kejkaew Thanasuan

The Journal of Problem Solving

The traveling salesman problem (TSP) is a combinatorial optimization problem that requires finding the shortest path through a set of points (“cities”) that returns to the starting point. Because humans provide heuristic near-optimal solutions to Euclidean versions of the problem, it has sometimes been used to investigate human visual problem solving ability. The TSP is also similar to a number of tasks commonly used for neuropsychological assessment (such as the trail-making test), and so its utility in assessing reliable individual differences in problem solving has sometimes been examined. Nevertheless, the task has seen little widespread use in clinical and assessment …

Duplication Of Pedipalp Segments In The Scorpion Androctonus Crassicauda (Olivier, 1807), Ayşegül Karataş, Mustafa Kürtüllü

Euscorpius

An unusual duplication of pedipalp segments is reported from the buthid scorpion Androctonus crassicauda. While the right pedipalp is normal, the anomaly described here occurred on the left pedipalp. This abnormally developed pedipalp included nine segments instead of normal six. It has two trochanters, two femurs and two patellae; the segments are arranged in the following order: coxa, trochanter I, femur I, patella I, trochanter II, femur II, patella II, chela hand, and movable finger. Morphometric measurements, photographs, and general features of the specimen are given.

Constellation Array In Scorpion Genera Paruroctonus, Smeringurus, Vejovoidus, And Paravaejovis (Scorpiones: Vaejovidae), Victor Fet, Michael E. Soleglad, Michael Brewer, David P. A. Neff, Michael L. Norton

Euscorpius

The constellation array (a recently discovered sensory structure on the fixed finger of pedipalp; Fet et al., 2006) is analyzed for a large set of species belonging to four genera in the family Vaejovidae: Paruroctonus, Smeringurus, Vejovoidus, and Paravaejovis. It is shown that this structure is an important taxonomic character. Two distinct configurations are identified, a two-sensilla array for Paruroctonus + Smeringurus + Vejovoidus and a three-sensilla array for genus Paravejovis, both differing from other vaejovid configurations so far investigated. The topology of these two array configurations are analyzed using landmark setae identified in this study.

Apparent Glacially Induced Structural Controls On Limestone Conduit Development In Ohio Caverns, United States, Adrienne M. Watts, Ira D. Sasowsky

International Journal of Speleology

Rock discontinuities such as bedding planes and joints are important controls on the form that caves take. We examined structural controls on the development of Ohio Caverns. The cave formed in Devonian limestone underlying a small bedrock knob (Mt. Tabor) within the Interior Lowland province, United States. The area has been overridden by continental glaciation multiple times. The bedrock is pervasively fractured, with many curved and wavy near-vertical fractures showing many different orientations. In the case of Ohio Caverns, it appears that the controlling fractures in map view may not be joints sensu stricto, but rather some combination of …

Tbx2 Represses Pten In Rhabdomyosarcoma And Skeletal Muscle., B Zhu, M Zhang, E M Williams, C Keller, A Mansoor, J K Davie

Articles

Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma in children that shares many features of developing skeletal muscle. TBX2, a T-box family member, is highly upregulated in tumor cells of both major RMS subtypes where it functions as an oncogene. TBX2 is a repressor that is often overexpressed in cancer cells and functions in bypassing cell growth control, including the repression of the cell cycle regulators p14 and p21. We have found that TBX2 directly represses the tumor-suppressor phosphatase and tensin homolog (PTEN) in both RMS and normal muscle. Exogenous expression of TBX2 in normal muscle cells downregulates PTEN, …

Dead Broets Society: Masculinity In Walt Whitman’S War Verse, Anika N. Jensen

The Gettysburg Compiler: On the Front Lines of History

There are two images of masculinity in Walt Whitman’s Drum-Taps, his collection of wartime poetry: one, the strong, hardened soldier, the image of manliness, and the other the boyish, rosy-cheeked recruit. Whitman’s sexuality, while not the Victorian social norm, was no secret, and he wrote openly of the hospitalized soldiers during his time as a Union nurse with admiration, affection, and love. Some critics, such as Thomas Wentworth Higginson, castigated Whitman’s queer themes to be overwhelming, distractingly sensual, and "unmanly," while others, like William Sloane Kennedy, dissented, arguing instead that the overt sexuality present in Whitman’s work was precisely …

In Central Falls, A Bold Design Signals A Bright Future, Public Affairs, Roger Williams University

Featured News Story

Graphic design students from RWU team with city officials to create a modern, bold brand identity that also embraces the community’s history.

Designed To Inspire: Local Officials Laud Students' Work On Ferry Terminal, Melissa A. Patricio

Featured News Story

Urban design studio partners with Fall River on City Pier Redevelopment Project via CPC.

Prion Protein Gene Sequence And Chronic Wasting Disease Susceptibility In White-Tailed Deer (Odocoileus Virginianus), Adam L. Brandt, Amy C. Kelly, Michelle L. Green, Paul Shelton, Jan Novakofski, Nohra E. Mateus-Pinilla

Faculty Creative and Scholarly Works

The sequence of the prion protein gene (PRNP) affects susceptibility to spongiform encephalopathies, or prion diseases in many species. In white-tailed deer, both coding and non-coding single nucleotide polymorphisms have been identified in this gene that correlate to chronic wasting disease (CWD) susceptibility. Previous studies examined individual nucleotide or amino acid mutations; here we examine all nucleotide polymorphisms and their combined effects on CWD. A 626 bp region of PRNP was examined from 703 free-ranging white-tailed deer. Deer were sampled between 2002 and 2010 by hunter harvest or government culling in Illinois and Wisconsin. Fourteen variable nucleotide positions …

12-21-2015 Swosu Plans Two Upcoming Panorama Events, Southwestern Oklahoma State University

THE BARK ARCHIVE 2015

Southwestern Oklahoma State University has two entertaining events planned for the upcoming 2016 spring semester as part of the 25th anniversary of the Panorama series on the Weatherford campus.

A Search For Correlations Between Gamma-Ray Burst Variability And Afterglow Onset, Sarah A. Yost

Physics Faculty Publications

We compared the time (or time limit) of onset for optical afterglow emission to the γ-ray variability V in 76 gamma-ray bursts with redshifts. In the subset (25 cases) with the rise evident in the data, we fit the shape of the onset peak as well and compared the rising and decaying indices to V. We did not find any evidence for any patterns between these properties and there is no statistical support for any correlations. This indicates a lack of connection between irregularities of the prompt γ-ray emission and the establishment of the afterglow phase. In the ordinary …

Location, Proximity, And M&A Transactions, Ye Cai, Xuan Tian, Han Xia

Finance

In this paper, we examine how the geographic location of firms affects acquisition decisions and value creation for acquirers in takeover transactions. We find that firms located in an urban area are more likely to receive a takeover bid and complete a takeover transaction as a target than firms located in rural areas, and takeover deals involving an urban target are associated with higher acquirer announcement returns, after controlling for the proximity between the target and the acquirer. In addition, a target's urban location significantly attenuates the negative effect of a long distance between the target and the acquirer on …

Summer-Long Grazing Of High Vs. Low Endophyte (Neotyphodium Coenophialum)-Infected Tall Fescue By Growing Beef Steers Results In Distinct Temporal Blood Analyte Response Patterns, With Poor Correlation To Serum Prolactin Levels, Joshua J. Jackson, Merlin D. Lindemann, James A. Boling, James C. Matthews

Animal and Food Sciences Faculty Publications

Previously, we reported the effects of fescue toxicosis on developing Angus-cross steer growth, carcass, hepatic mRNA, and protein expression profiles of selected serum proteins, and blood clinical and chemical profiles, after summer-long grazing (85 days) of high endophyte (HE)- vs. low endophyte (LE)-infected fescue pastures. We now report the temporal development of acute, intermediate, and chronic responses of biochemical and clinical blood analytes determined at specified time intervals (period 1, day 0–36; period 2, day 37–58; and period 3, day 59–85). Throughout the trial, the alkaloid concentrations of the HE forage was consistently 19–25 times greater (P ≤ 0.002) …

12-21-2015 Weatherford Aauw To Host Oklahoma Women's Coalition Executive Director, Southwestern Oklahoma State University

THE BARK ARCHIVE 2015

Danielle Ezell, executive director of the Oklahoma Women’s Coalition, will be speaking in Weatherford on Friday, January 22, and her talk is open to the public.

The Murray Ledger And Times, December 21, 2015, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

California Dreamin', Beth Potier

UNH Today Archive

No abstract provided.

Translating Transformative Human Rights Education Through Visual Languages & Informal Spaces, Jazzmin Chizu Gota

Master's Projects and Capstones

This project examines methods, theories, and practices of translating human rights education through multiple vernaculars. Developed as a workshop in sociocultural syntax deconstruction and an educational human rights education website focused on the domestic population of the US, the project focuses on localizing human rights concepts to the public vernacular of the country. Human rights education (HRE) and media and information literacy (MIL) are expanded and redefined as social literacy, or the ability to navigate and decode the present, complex realities that both HRE and MIL were developed to address. Reframing media and visual arts as an archive of past …

Selection For Forage And Avoidance Of Risk By Woodland Caribou (Rangifer Tarandus Caribou) At Coarse Andlocal Scales, Madeleine T. Mcgreer, Erin E. Mallon, Lucas M. Vander Vennen, Philip A. Wiebe, James A. Baker, Glen S. Brown, Tal Avgar, Jevon Hagens, Andrew M. Kittle, Anna Mosser, Garrett M. Street, Doug E. B. Reid, Arthur R. Rodgers, Jennifer Shuter, Ian D. Thompson, Et Al.

Wildland Resources Faculty Publications

The relationship between selection at coarse and fine spatiotemporal spatial scales is still poorly understood. Some authors claim that, to accommodate different needs at different scales, individuals should have contrasting selection patterns at different scales of selection, while others claim that coarse scale selection patterns should reflect fine scale selection decisions. Here we examine site selection by 110 woodland caribou equipped with GPS radio‐collars with respect to forage availability and predation risk across a broad gradient in availability of both variables in boreal forests of Northern Ontario. We tested whether caribou selection for forage and avoidance of risk was consistent …

Advent: Hoping In The Bigger Picture, Brandon Huisman

Staff Work

"I am always thinking about what is next and wondering what God is doing in his bigger picture, yet Simeon seems to remind us to sit back in the spirit and lean into him."

Posting about waiting for God's plan to unfold ­­­­­­­­from In All Things - an online hub committed to the claim that the life, death, and resurrection of Jesus Christ has implications for the entire world.

http://inallthings.org/advent-hoping-in-the-bigger-picture/