Digital Commons Network^™

Interaction Between Angiotensin Ii And Bdnf In Modulating Sympathetic Nerve Activity, Bryan K. Becker

Theses & Dissertations

Over activation of the sympathetic nervous system is prevalent in many forms of cardiovascular disease such as chronic heart failure (CHF) and hypertension. Although increased neuronal renin-angiotensin system activity in presympathetic neurons has been well implicated in mediating this sympatho-excitation, many of the neuronal effects of angiotensin II (Ang II) signaling remain poorly understood. One particular mechanism of Ang II-mediated increases in presympathetic neuronal activity is through reductions in voltage-gated K⁺ currents. Another pathway that has profound effects on neuronal K⁺ currents and that has been previously implicated in Ang II-signaling is brain-derived neurotrophic factor (BDNF) activity through …

Postural Responses To Perturbations Of The Vestibular System During Walking In Healthy Young And Older Adults, Jung Hung Chien

Theses & Dissertations

It has been shown that approximate one-third of US adults aged 40 years and older (69 million US citizens) have some type of vestibular problems. These declining abilities of the vestibular system affect quality of life. Difficulties in performing daily activities (dressing, bathing, getting in and out of the bed and etc.) have been highly correlated to loss of balance due to vestibular disorders. The exact number of people affected by vestibular disorders is still difficult to quantify. This might be because symptoms are difficult to describe and differences exist in the qualifying criteria within and across studies. Thus, it …

The Role Of Tumor Suppressor Co-Chaperone Chip/Stub1 In Erbb2-Mediated Oncogenesis, Haitao Luan

Theses & Dissertations

The epidermal growth factor receptor (EGFR) family member ErbB2 (Her2) is overexpressed in 20 -30% of invasive breast cancers and this overexpression correlates with poor prognosis and shorter overall as well as disease-free survival. Aberrant expression of ErbB2 through gene amplification, transcriptional deregulation and/or altered endocytic trafficking results in overexpression of ErbB2 at the plasma membrane and biases ErbB2 from primarily ligand-driven hetero-dimerization under normal expression conditions to increased ligand-independent homo-dimer and hetero-dimer formation and consequent activation. C-terminus of HSC70-Inteeracting protein (CHIP)/STIP1-homologous U-Box containing protein 1 (STUB1) is an HSP90/HSC70 interacting negative co-chaperone known to promote ubiquitination and degradation of …

The Effects Of Severe Weather Warnings On Limited English Proficient (Lep) Hispanics/Latinos In Rural Nebraska, Joan E. Nelson

Theses & Dissertations

The language barrier may severely restrict how severe weather warnings are received and responded to by Hispanics/Latinos in rural Nebraska, a state well known for frequent, volatile weather patterns. Nearly 50% of Spanish speaking Nebraskans rated their English abilities as “less than very well” (US Census Bureau, 2013). The estimated number of Hispanics/Latinos with limited English proficiency (LEP) in Nebraska equates to approximately 57,000 people. This thesis attempted to assess English ability and how severe weather warnings were received and responded to by LEP Hispanics/Latinos in rural Nebraska. This was accomplished by analysis of data from completed optional Spanish or …

A Role For Ehd Family Endocytic Regulators In Endothelial Biology, Alexandra E. J. Moffitt

Theses & Dissertations

Endocytic trafficking is an essential process in eukaryotic cells, specifically for the transport of nutrients, membrane components, and receptors. Cargo destined for endocytic traffic is internalized at the cell surface via clathrin-dependent and clathrin-independent pathways, and brought to the early or sorting endosomes. From there, cargo is further trafficked to lysosomes for degradation, trafficked to other compartments in the cell, or recycled back to the cell surface (either directly or via the endocytic recycling compartment).

Mammalian C-terminal Eps15 homology domain-containing proteins, or EHD proteins (EHD1 to 4), are a family of highly conserved ATPases that function as key regulators of …

The Effect Of Body Mass Index On Graft Function And Kidney Transplant Outcomes, Morgan Galle

Theses & Dissertations

Background: When determining eligibility for kidney transplantation, body mass index (BMI) is often a debatable criterion for transplant due to the clinical indication, an elevated BMI has adverse effects on kidney transplant outcomes. There is a current gap in research on the effect BMI has on kidney transplant outcomes.

Purpose: The purpose of this study was to determine the role BMI plays in post-kidney transplant clinical outcomes including delayed graft function, new onset diabetes after transplant, wound complications, hospital length of stay, albumin, and readmissions to the hospital from initial hospitalization and at six months following kidney transplantation. The primary …

Evaluation Of The Efficiency Of And Preference For Analog Versus Mand Training On The Acquisition Of Mands For Children With Autism Spectrum Disorder, Melissa L. King

Theses & Dissertations

The present study provides a systematic replication of the Jennett, Harris, and Delmolino (2008) study comparing discrete trial instruction (DTI) and mand training on the acquisition of mands for children with autism spectrum disorder (ASD). An adapted alternating treatment design was implemented across three participants. Independent mands, variation in requested items, and duration of sessions were assessed across conditions. Generalization probes were conducted to assess generalization across communication partners (e.g., novel research assistants), along with a maintenance probe one-week post-training. Furthermore, a concurrent-chains arrangement was implemented to assess participants’ preference for teaching strategies. All participants reached mastery criterion quickest with …

Developing And Testing An Anguilliform Robot Swimming With Theoretically High Hydrodynamic Efficiency, John B. Potts Iii

LSU New Orleans Theses and Dissertations

An anguilliform swimming robot replicating an idealized motion is a complex marine vehicle necessitating both a theoretical and experimental analysis to completely understand its propulsion characteristics. The ideal anguilliform motion within is theorized to produce ``wakeless'' swimming (Vorus, 2011), a reactive swimming technique that produces thrust by accelerations of the added mass in the vicinity of the body. The net circulation for the unsteady motion is theorized to be eliminated.

The robot was designed to replicate the desired, theoretical motion by applying control theory methods. Independent joint control was used due to hardware limitations. The fluid velocity vectors in the …

Fort Hays State University Tiger Weekly, December 18, 2015, University Relations

Tiger Weekly Newsletters

No abstract provided.

T.S. Eliot: A Never-Ending Exploration, Kristina Krupilnitskaya

Honors Thesis

The following thesis explores the work of T.S. Eliot before and after his conversion to the Anglican Church. While the paper explores the stylistic qualities of Eliot's poetry, the main focus of the essay lies in bridging the pre and post conversion works together in order to show that both of the periods were significant in the poet's life. While many critics viewed Eliot's early poetry as a lot more exploratory and challenging, calling his later poetry banal and bland, my essay aims to show that even though the poetry had shifted in its content, its significance, complexity, and experimentality …

Characters Through Time, Alyssa Venezia

Honors Thesis

T. S. Eliot once wrote that we “often find that not only the best, but the most individual parts of [an author’s] work may be those in which the dead poets, his ancestors, assert their immortality most vigorously” (Eliot 37). By focusing on character adaptations, one comes to understand how authors of children’s books are able to adapt classic literature into age-appropriate texts that retain the merits of the original. Five sets of characters shall be analyzed to demonstrate the success of the adaptations presented in children’s literature. In the first, Sir Bedivere from Sir Thomas Malory’s Le Morte Darthur …

Paleostress States And Tectonic Evolution Of The Early Mesozoic Hartford Basin, James Farrell

Master's Theses

No abstract provided.

“How Do You Define Yourself?” Mobilizing Leadership In The Graduate Employee Union Movement, Kathleen Ragon

Master's Theses

Social movement scholars agree that leadership plays a crucial role in the emergence, structure, and outcomes of social movement organizations (SMOs) and is thus an indispensable area of research. The vast majority of theories of leadership to date have been developed in contexts where participants’ movement identities are relatively stable (e.g., gender, sexual, or occupational) and engagement in the site of contestation will be long-term (e.g., workplace or nation state). However, the recent proliferation of graduate student employee unions poses a challenge to this literature because graduate students’ employment is by its very nature temporary and variable; graduate assistantship appointments …

Correction Of Verication Bias Using Log-Linear Models For A Single Binaryscale Diagnostic Tests, Haresh Rochani, Hani M. Samawi, Robert L. Vogel, Jingjing Yin

Biostatistics: Faculty Publications

In diagnostic medicine, the test that determines the true disease status without an error is referred to as the gold standard. Even when a gold standard exists, it is extremely difficult to verify each patient due to the issues of costeffectiveness and invasive nature of the procedures. In practice some of the patients with test results are not selected for verification of the disease status which results in verification bias for diagnostic tests. The ability of the diagnostic test to correctly identify the patients with and without the disease can be evaluated by measures such as sensitivity, specificity and predictive …

Prolongation Of The Greek Financial Support Measures (Art. 2 Law 3723/2008), European Union: European Commission, Margrethe Vestager

Documents

Margrethe VESTAGER Member of the Commission State aid SA.43825 (2015/N)

State Of Utah, Plaintiff/Appelle, Vs. Colorado Steven Irwin, Defendant/Appellant : Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (2007– 2019)

Appeal from a restitution order following guilty please to Theft by Receiving Stolen Property, a third degree felony, in violation of Utah Code 76-6-408, and Burglary, a third degree felony, in violation of Utah Code 76-6-202, in the Third District Court, in and for Salt Lake County, State of Utah, the Honorable Charlene Barlow presiding

An Empirical Survey Of International Commercial Arbitration Cases In The Us District Court For The Southern District Of New York, 1970-2014, Vera Korzun, Thomas H. Lee

Fordham International Law Journal

This Article identifies and organizes the circumstances in which national courts play a role in international commercial arbitrations— border crossings. It then records and analyzes empirical data of these border crossings in cases filed in a key national court for international arbitration-related litigation: the US District Court for the Southern District of New York. Data were collected from the date of entry into force for the United States of the New York Convention on the Recognition and Enforcement of Foreign Arbitral Awards (the “New York Convention”) on December 29, 1970 to September 15, 2014. Based on interpretation of these data, …

State V. Hoerster Appellant's Brief Dckt. 43064

Not Reported

No abstract provided.

The Role Of The State, Multinational Oil Companies, International Law & The International Community: Intersection Of Human Rights & Environmental Degradation Climate Change In The 21st Century Caused By Traditional Extractive Practices, The Amazon Rainforest, Indigenous People And Universal Jurisdiction To Resolve The Accountability Issue, Marcela Cabrera Luna

Master's Theses

Local, national and international conventions that protect indigenous sovereignty and their territories, where many of the resources are extracted from by multinational corporations (MNCs) particularly oil, the number one commodity of the world and cause of climate change, continue to be jeopardized because of the lack of a clear international legal framework that can protect them and potentially hold multinationals accountable for their actions. These practices are causing not only environmental issues to the indigenous and surrounding communities, but climate change is in fact, the real human rights issue of the 21^st century and it affects everyone. By using …

Uruguay’S Governing Alliance Deeply Divided Over Foreign Policy, Andrã©S Gaudã­N

NotiSur

No abstract provided.

Implementing Emergency Bedside Backpacks In The Nicu To Improve Patient Outcomes, Melissa M. Garcia

Master's Projects and Capstones

Abstract

Planning for a disaster, by implementing a unit specific disaster plan, has become an essential recommendation for Neonatal Intensive Care Units. Emergent situations have resulted from past natural disasters proving the need for additional planning when it comes to units with fragile populations. Research has shown instituting a specialized disaster plan, increases patient safety resulting in improved patient outcomes. This prospectus aims to implement emergency bedside backpacks as the first step in the development of a NICU specific disaster plan. These backpacks are meant to be an addition to the current hospital emergency plan, with the goal being to …

Implementation Of A Warming Protocol To Prevent Inadvertent Perioperative Hypothermia In The Ambulatory Surgical Setting, Joan Abigail Slagle

Master's Projects and Capstones

The implementation of a standardized warming protocol aims to improve patient outcomes by preventing inadvertent perioperative hypothermia (IPH) and its complications in the ambulatory surgical setting. All patients, regardless of age or gender, are at risk for experiencing a 1-2° C drop in body core temperature within thirty minutes of anesthesia induction. The global aim of this project is to prevent IPH and its complications in the ambulatory surgical setting by implementing a warming protocol at a freestanding ambulatory surgery center. While an audit of the microsystem revealed a normothermia rate of 28%, a standardized warming protocol is expected to …

Alarm Management: Electrocardiographic Lead Management, Dale Elaine Dominguez Ms.

Master's Projects and Capstones

Abstract

Alarm Management: Electrocardiographic Lead Management

Quality improvement and safety that incorporates the Clinical Nurse Leader (CNL) competency of putting in place quality improvements plans that are bases on evidence, analysis, and risk anticipation is the thesis for this project. The associated problem is the myriads of electrocardiographic (ECG) alarms that alert staff to patient issues each day. Of those alerts, 88% to 90% are false or do not require immediate attention (Sendelbach & Jepsen, 2013). The high numbers of false alerts cause staff to become desensitized to the sound. This desensitization may cause staff not to respond to a …

Decrease Arrival To Ct Time To Improve Stroke Outcomes, Curt Peterson

Master's Projects and Capstones

Abstract Final

The specific goal of the project is to decrease the arrival to t-PA treatment times to <45 minutes in > 50% of the cases. The decreased treatment time will prove to shorten the average length of stay on average by two days (Audebert & Sobesky, 2014). The goal will be accomplished by decreasing the arrival to computerized tomography (CT) scan completion time by at least 20%. The specific population of patients will be all stroke alert arrivals to the process’s microsystem via EMS, an Advanced Primary Stroke Center in Sacramento California. Root Cause Analysis, Strength, Weakness, Opportunity, Threat (SWOT), and Plan, Do, …

Empowering Patients With Central Venous Catheters: Utilizing Evidence-Based Video-Assisted Education To Reduce Central Line-Associated Bloodstream Infections, Pritam C. Steiner

Master's Projects and Capstones

An evidence-based Central Venous Catheter (CVC) dressing change video was created to enhance patient independence, and to increase resource efficiency among nursing staff in an inpatient pediatric setting in which Central Line-Associated Bloodstream Infection (CLABSI) rates were rising. Pediatric oncology patients confer the highest risk of developing CLABSIs due to long-term CVC access, neutropenic effects of treatment regimens, and constant fluctuations between inpatient, outpatient clinic, and homecare settings. Use of video-assisted education is anticipated to standardize and improve patient care, decrease healthcare costs, and increase nurse productivity, and is widely supported by research. Qualitative data collection was conducted by surveying …

Barriers To Leaving Poverty, Aouie R. Rubio

Master's Projects and Capstones

Rubicon Programs transformed its programs through recent strategic planning efforts to address the change in their mission that refocuses their goal on the eradication of poverty. The challenge for the design team was reimagining with fresh eyes the organization’s programs and service delivery model by examining what is needed from a holistic approach to move individuals out of poverty; becoming self-sufficient without recidivating back to poverty levels. This focus on moving people out of poverty and increasing sustainable self-sufficiency and not simply finding employment adds a complex level of program design aspects to consider. It is important for the participant …

Hepatitis C: A Perspective Through The Social Ecological Model, Sandra H. Vulis

Master's Projects and Capstones

Hepatitis C virus (HCV) is a major global public health problem. The Center for Disease Control and Prevention (CDC) estimates that the Hepatitis C virus (HCV) affects 3.2 million Americans and 500 million people from a global standpoint (CDC, 2012). HCV contributes to significant morbidity and mortality with about 1 million deaths due to liver disease (World Hepatitis Alliance, 2010). Chronic liver disease has origins ranging from acquired, infectious, toxic and metabolic causes. Long-term consequences include cancer, cirrhosis (scarring of the liver), and liver failure. Given the substantial data attributable to HCV-related liver disease, it is necessary to develop an …

Urban Stormwater Management: Treatment Of Heavy Metals And Polycyclic Aromatic Hydrocarbons With Bioretention And Permeable Pavement Technologies, Viktoriya Sirova

Master's Projects and Capstones

Urban stormwater runoff is a major non-point source of pollutants release into the environment. Pollutants of concern include sediments; heavy metals; polycyclic aromatic hydrocarbons (PAHs); petroleum hydrocarbons; and chlorinated organic compounds, such as pesticides and polychlorinated biphenyls. Conventional stormwater management practices are designed to dispose of the runoff as quickly as possible, not to treat the pollutants. Low Impact Development (LID) concept is an alternative approach to the conventional framework that attempts to recreate hydrologically functional landscape mimicking pre-development regimes. This research paper assesses the effectiveness of two LID technologies, bioretention and permeable pavements in treating PAHs and common urban …

The Effects Of An Overnight Environmental Science Education Program On Students' Attendance Rate Change For Middle School Years, Jennifer Elizabeth Basham

Dissertations and Theses

Programs that engage middle students in participatory, real-world, and hands-on field based instruction can be a powerful asset to the educational experiences for students; motivating and inspiring some to appreciate and value school in a different way. Overnight environmental science programs have a unique opportunity to support students by creating experiences where students can participate in learning in vastly different ways from what they may engage with in the traditional 4-walled classroom, while concurrently developing a relationship with the natural world. Decreasing educational budgets and increased need to substantiate educational programs in terms of their impact on students has added …

Extension Agriculture And Natural Resources In The U.S. Midwest: A Review And Analysis Of Challenges And Future Opportunities, Mahdi M. Al-Kaisi, Roger Wesley Elmore, Gerald A. Miller, David Kwaw-Mensah

Department of Agronomy and Horticulture: Faculty Publications

This review addresses key changes in U.S. agricultural extension and future opportunities. Agricultural extension has been a part of the land-grant university (LGU) system for more than 100 years. The Morrill Act of 1862 established the LGU system by authorizing states access to federally controlled land and funding for public institutions offering educational opportunities focusing on agriculture and mechanical arts for farmers and the working class. Current surveys in Iowa reveal changing trends in extension: more than 90% of farmers identified private-sector crop advisers as their primary source for recommendations, whereas more than 80% of those advisors identified Iowa State …