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Heavy Vehicle Crash Characteristics In Oman : 2009–2011, Islam Al-Bulushi, Jason Edwards, Jeremy Armstrong, Kerry, Hamed Al-Reesi, Khalid Al-Shamsi

Sultan Qaboos University Medical Journal

In recent years, Oman has seen a shift in the burden of diseases towards road accidents. The main objective of this paper, therefore, is to describe key characteristics of heavy vehicle crashes in Oman and identify the key driving behaviours that influence fatality risks. Crash data from January 2009 to December 2011 were examined and it was found that, of the 22,543 traffic accidents that occurred within this timeframe, 3,114 involved heavy vehicles. While the majority of these crashes were attributed to driver behaviours, a small proportion was attributed to other factors. The results of the study indicate that there …

Plague Inc: Distribution Of Health Resources In The Modern World, Allison Rump

Honors Theses

Due to the ever increasing connectedness of our world, disease can spread faster than ever before. Therefore global health care is a pressing issue in the modern world. The Ebola epidemic of 2014, which infected an unprecedented number of people, was reminder of not only of human fragility but of the state modern medicine, especially when deployed in economically developing areas. Not only is medicine about the science and treatment of disease, it also is about economics and the ability to pay for treatment. This can manifest in many forms, for the Ebola epidemic there often were not enough equipment …

17th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

Emerging Roles Of Health Care Providers To Mitigate Climate Change Impacts: A Perspective From East Harlem, New York, Perry E. Sheffield, Kathleen T. Durante, Elena Rahona, Christina Zarcadoolas

Publications and Research

Professional associations of health care workers are issuing policy statements on climate change and health with greater frequency, calling on their members to act in their duty to protect and fulfill the right to health. These health care providers’ perceptions of their roles in the intersection of climate and health, however, have not been well-studied. This article presents results from a qualitative study using focus groups conducted with health care providers serving the low-income, ethnic minority population in East Harlem, New York. The focus groups sought to identify and explore providers’ perceived health threats of climate change, as well as …

Triatominae (Hemiptera:Reduviidae) In Texas: Mitochondrial Genome Assembly, Trypanosoma Cruzi Detection, And Bacterial Community Analysis, Chissa-Louise Rivaldi

Biology Theses

The genus Triatoma contains vectors of the protozoan parasite Trypanosoma cruzi, the pathogen responsible for Chagas disease. The following research presents several inductive studies to develop vector control approaches targeted to the genus or species level. Two-hundred and eighty-two insects were collected, identified, and tested for the presence of T. cruzi. Four species of the Triatoma genus were collected - the overall incidence of T. cruzi was 52% (T. gerstaeckeri -51%, T. lecticularia – 92%, other, 29%). From these 282 insects, the bacterial communities of eight specimens of T. gerstaeckeri were sequenced and analyzed using pyrosequencing technology. The bacterial communities …

Synthesis And Biological Evaluation Of N-Alkoxyphenyl-3-Hydroxynaphthalene-2-Carboxanilides, Eoghan Nevin, Aidan Coffey, Jim O'Mahony, Et. Al.

Department of Biological Sciences Publications

A series of fifteen new N-alkoxyphenylanilides of 3-hydroxynaphthalene-2-carboxylic acid was prepared and characterized. Primary in vitro screening of the synthesized compounds was performed against Staphylococcus aureus, three methicillin-resistant S. aureus strains, Mycobacterium tuberculosis H37Ra and M. avium subsp. paratuberculosis. Some of the tested compounds showed antibacterial and antimycobacterial activity against the tested strains comparable with or higher than that of the standards ampicillin or rifampicin. 3-Hydroxy-N-(2-propoxyphenyl)naphthalene-2-carboxamide and N-[2-(but-2-yloxy)-phenyl]-3-hydroxynaphthalene-2-carboxamide had MIC = 12 µM against all methicillin-resistant S. aureus strains; thus their activity is 4-fold higher than that of ampicillin. The second mentioned compound as well as 3-hydroxy-N-[3-(prop-2-yloxy)phenyl]-naphthalene-2-carboxamide had MICs = …

Phylogeography Of Southeast Asian Flying Foxes (Chiroptera: Pteropodidae: Pteropus), Susan Man Shu Tsang

Dissertations, Theses, and Capstone Projects

Flying foxes (Pteropus) are a genus of Old World fruit bats that are important seed dispersers and pollinators for plants native to the 200,000+ islands in Southeast Asia, yet they are some of the most poorly known bats in the world. They comprise some of the largest known bat species, and are morphologically relatively conserved on the genus level. Pteropus is the most species-rich genus within Pteropodidae, though the origin for this diversity remains incompletely understood. In Chapter 1, I discuss the importance of Pteropus to the ecosystem and as reservoir hosts. In Chapter 2, a molecular phylogeny is presented …

An Introduction To St. Luke's Hospital: Medical Student And Resident Manual, 1980, Advocate Aurora Health

Aurora St. Luke’s Medical Center Books, Documents, and Pamphlets

St. Luke's Hospital: A 1980 manual for St. Luke's Hospital. The manual's purpose was to help orient medical students and residents during their time at the hospital. The manual includes a list of administrators, medical staff, student/resident rules and responsibilities, dress code, payroll information, general hospital policies such as visiting hours, areas that allowed smoking, and a directory including specific department information.

Antibacterial Activity Of Native California Medicinal Plant Extracts Isolated From Rhamnus Californica And Umbellularia Californica., Maria G. Carranza, Mary B. Sevigny, Debashree Banerjee, Lacie Fox-Cubley

Natural Sciences and Mathematics | Faculty Scholarship

BACKGROUND: Antimicrobial resistance (AMR) is a major threat to global public health. Medicinal plants have long been used as remedies for infectious diseases by native cultures around the world and have the potential for providing effective treatments for antibiotic-resistant infections. Rhamnus californica (Rhamnaceae) and Umbellularia californica (Lauraceae) are two indigenous California plant species historically used by Native Americans to treat skin, respiratory and gastrointestinal infections. This study aimed to assess the in vitro antimicrobial activity of methanolic extracts of leaves and bark of R. and U. californica against methicillin-resistant Staphylococcus aureus (MRSA) and other Gram-positive and Gram-negative bacteria.

METHODS: Methanolic …

Improving Hpv Vaccinations In Military Women, Sarah Beth Wedel

Doctor of Nursing Practice Final Manuscripts

Project Purpose: The purpose of the project was to implement Human Papillomavirus (HPV) patient education during every well woman exam (WWE) to improve patient knowledge and HPV vaccination rates in military women aged 18-26 years.

Background: The Human Papillomavirus (HPV) has been identified as the biggest risk factor for cervical cancer and, despite the availability of a vaccine; HPV continues to be the most common STI in the U. S. (American Cancer Society, 2013). Approximately 79 million Americans are currently infected with HPV, and 14 million individuals will become infected annually, leading to more than 10,000 cases of cervical cancer …

Antigen Discovery For The Identification Of Vaccine Candidates And Biomarkers Using A T Cell Driven Approach In Combination With Positional Scanning Peptide Libraries, Valeria A. Judkowski, Radleigh Santos, Gonzalo R. Acevedo, Marc Giulianotti, Jon R. Appel, Silvia A. Longhi, Karina A. Gomez, Clemencia Pinilla

Mathematics Faculty Articles

The prevention and treatment of infectious diseases is highly dependent on the availability of reliable diagnostic tests and protective or therapeutic vaccines. There also exists an urgent need to develop reliable biomarkers to monitor treatment success and to predict disease progression from asymptomatic to symptomatic disease in several disease scenarios. The elucidation of the disease-relevant antigens that elicit the protective immune responses is critical and required for the development of biomarkers, diagnostics, and vaccines. However; one of the main obstacles to the study of antigen specificity in human T cells is their low frequency in PBMC samples. To overcome this …

Human Dna Exonuclease Trex1 Is Also An Exoribonuclease That Acts On Single-Stranded Rna, Fenghua Yuan, Tanmay Dutta, Ling Wang, Lei Song, Liya Gu, Liangyue Qian, Anaid Benitez, Shunbin Ning, Arun Malhotra, Murray P. Deutscher, Yanbin Zhang

Toxicology and Cancer Biology Faculty Publications

3' repair exonuclease 1 (TREX1) is a known DNA exonuclease involved in autoimmune disorders and the antiviral response. In this work, we show that TREX1 is also a RNA exonuclease. Purified TREX1 displays robust exoribonuclease activity that degrades single-stranded, but not double-stranded, RNA. TREX1-D200N, an Aicardi-Goutieres syndrome disease-causing mutant, is defective in degrading RNA. TREX1 activity is strongly inhibited by a stretch of pyrimidine residues as is a bacterial homolog, RNase T. Kinetic measurements indicate that the apparent K_m of TREX1 for RNA is higher than that for DNA. Like RNase T, human TREX1 is active in degrading native …

Pre-Exposure Prophylaxis (Prep) Education Improvement Project, Reginald M. Hilarie

Master's Projects and Capstones

In 2012, the US Food and Drug Administration approved the pill Truvada for use as pre-exposure prophylaxis or PrEP. Its purpose is to help prevent HIV infection by taking one pill every day. This project aims to improve PrEP patient education provided by the multi-disciplinary team and to decrease new HIV infection and sexually transmitted infections (STIs) to zero. The focus of the study is patients on PrEP at the Infectious Disease and HIV Clinic in San Francisco Veterans Administration Medical Center. The Clinical Nurse Leader, in collaboration with the multidisciplinary team, incorporated Pender’s Health Promotion Model Theory in developing …

Improving Hand Hygiene Compliance To Reduce Clabsi Rate In Oncology Icu, Lorenzo D. San Pedro

Master's Projects and Capstones

The aim of this project is to reduce the rate of central line associated blood stream infection (CLABSI) occurrence in oncology ICU by 50% by the last quarter of 2015. This study was conducted in ICU to assess adherence to the facility’s hand hygiene (HH) protocol among the staff nurses and allied healthcare workers. The facility is best known as a non-profit cancer treatment center and designated as a Comprehensive Cancer Center. Evidence showed that hand hygiene is the most effective way of preventing CLABSI, one of the most common types of infection in ICU microsystem. The project utilized The …

A Geospatial Analysis Of Norovirus Outbreaks In California, And An Investigation Of The Impact Of Environmental Variables, Alexandra Groen

Master's Projects and Capstones

Previous studies and empirical evidence suggest norovirus outbreaks in California exhibit correlation with environmental variables and exhibit spatial spread patterns. Few studies have been done looking at what causes norovirus seasonality in temperate climates and more research is needed on the regional level. This study aims to find what relationships exist with outbreak occurrence and environmental variables in California, as well as any spatial patterns of spread or clustering of outbreaks. Spatial analysis tools were used to find any relationships between California norovirus outbreak data and environmental variables. The results showed a south to north spread of outbreaks in California …

Investigations Of Thioether Generation For S-D-Ribosyl-L-Homocysteine Synthesis, Brendan Corcoran

Master's Theses

Creation of the thioether linkage is a fundamental step for the chemical preparation of the bacterial quorum sensing molecule S-D-ribosyl-L-homocysteine (SRH). Although previous preparations of SRH and its analogues have been reported in the literature, they employ assorted methods with varied results. Therefore, a reassessment of the methodology used for synthetic preparation of the thioether bond in SRH-like molecules is here considered. This work examines four methods of thioether generation following two mechanisms, bimolecular nucleophilic substitution (S_N2) and radical-initiated thiol-ene coupling, in an attempt to generate SRH in a more efficient and reproducible manner. Both mechanisms address …

Different Populations Of Blacklegged Tick Nymphs Exhibit Differences In Questing Behavior That Have Implications For Human Lyme Disease Risk, Isis M. Arsnoe, Graham J. Hickling, Howard S. Ginsberg, Richard Mcelreath, Jean I. Tsao

Plant Sciences and Entomology Faculty Publications

Animal behavior can have profound effects on pathogen transmission and disease incidence. We studied the questing (= host-seeking) behavior of blacklegged tick (Ixodes scapularis) nymphs, which are the primary vectors of Lyme disease in the eastern United States. Lyme disease is common in northern but not in southern regions, and prior ecological studies have found that standard methods used to collect host-seeking nymphs in northern regions are unsuccessful in the south. This led us to hypothesize that there are behavior differences between northern and southern nymphs that alter how readily they are collected, and how likely they are …

Swirl Flow Bioreactor Coupled With Cu-Alginate Beads: A System For The Eradication Of Coliform And Escherichia Coli From Biological Effluents, S Atkinson, Sf Thomas, P Goddard, Rm Bransgrove, Et Al

School of Geography, Earth and Environmental Sciences

It is estimated that approximately 1.1 billion people globally drink unsafe water. We previously reported both a novel copper-alginate bead, which quickly reduces pathogen loading in waste streams and the incorporation of these beads into a novel swirl flow bioreactor (SFB), of low capital and running costs and of simple construction from commercially available plumbing pipes and fittings. The purpose of the present study was to trial this system for pathogen reduction in waste streams from an operating Dewats system in Hinjewadi, Pune, India and in both simulated and real waste streams in Seattle, Washington, USA. The trials in India, …

Uab To Host Top Names In Infectious Disease Research, Traci Bratton

Browse All News

No abstract provided.

Adrenal Gland And Lung Lesions In Gulf Of Mexico Common Bottlenose Dolphins (Tursiops Truncatus) Found Dead Following The Deepwater Horizon Oil Spill, Stephanie Venn-Watson, Kathleen M. Colegrove, Jenny Litz, Michael Kinsel, Karen Terio, Jeremiah Saliki, Spencer Fire, Ruth Carmichael, Connie Chevis, Wendy Hatchett, Jonathan Pitchford, Mandy Tumlin, Cara Field, Suzanne Smith, Ruth Ewing, Deborah Fauquier, Gretchen Lovewell, Heidi Whitehead, David Rotstein, Wayne Mcfee, Erin Fougeres, Teri Rowles

Ocean Engineering and Marine Sciences Faculty Publications

A northern Gulf of Mexico (GoM) cetacean unusual mortality event (UME) involving primarily bottlenose dolphins (Tursiops truncatus) in Louisiana, Mississippi, and Alabama began in February 2010 and continued into 2014. Overlapping in time and space with this UME was the Deepwater Horizon (DWH) oil spill, which was proposed as a contributing cause of adrenal disease, lung disease, and poor health in live dolphins examined during 2011 in Barataria Bay, Louisiana. To assess potential contributing factors and causes of deaths for stranded UME dolphins from June 2010 through December 2012, lung and adrenal gland tissues were histologically evaluated from 46 fresh …

Fueling The Flame: Complementary And Alternative Methods To Prevent Burnout, Natalie Masco Dixon

Nursing Faculty/Staff Publications

Do you feel tired, stressed or overwhelmed? Do you have little time to care for yourself or are looking for new ways to bring wellness to your life? Nurses must be healed in order to heal. Modalities often considered complementary or alternative may offer the rejuvenation in your health and wellness you have been looking for! This session introduces the audience to common causes of burnout and ways in which acute and critical care nurses can find balance in their own lives through self-care practices. Modalities to be examined and practiced include centering, mindfulness, acupressure and aromatherapy. Personal experiences with …

Nsf Grant Helps Preserve Parasite Collections [Press Release], Scott Gardner, Leslie Reed

Scott L. Gardner Publications

The National Science Foundation has awarded a $500,000 grant that will allow four major parasite collections to be digitized. The collections are part of UNL's Harold W. Manter Laboratory of Parasitology. Scott Gardner (pictured) is the curator and director of the Manter Laboratory.

A $500,000 grant from the National Science Foundation will allow the Harold W. Manter Laboratory of Parasitology to digitally preserve four major collections of parasite specimens donated to the University of Nebraska-Lincoln during the past five years.

Marie Olivieri Russell And Sarah Sundborg Long, Sarah Long, Marie Russell, Kelsey Duinkerken

First Women at Jefferson Oral Histories

Marie Olivieri Russell

Dr. Russell attended Jefferson Medical College where she graduated top of her class in 1970. In addition to being the first woman to receive the Alumni Prize for highest cumulative GPA, in 1971 she became the first student to serve as a full voting member of the Board of Trustees at Jefferson. After graduation she completed both a residency in Pediatrics and a fellowship in Pediatric Hematology Oncology at Children’s Hospital of Philadelphia before continuing on as a part of their academic staff until 1981 and managing the Comprehensive Sickle Cell Program. After leaving Children’s and academic …

Exploring The Complex Pattern Of Information Spreading In Online Blog Communities, Sen Pei, Lev Muchnik, Shaoting Tang, Zhiming Zheng, Hernán A. Makse

Publications and Research

Information spreading in online social communities has attracted tremendous attention due to its utmost practical values in applications. Despite that several individual-level diffusion data have been investigated, we still lack the detailed understanding of the spreading pattern of information. Here, by comparing information flows and social links in a blog community, we find that the diffusion processes are induced by three different spreading mechanisms: social spreading, self-promotion and broadcast. Although numerous previous studies have employed epidemic spreading models to simulate information diffusion, we observe that such models fail to reproduce the realistic diffusion pattern. In respect to users behaviors, strikingly, …

Week Of May 18, 2015, New York Medical College

InTouch

• Dr. Jan K. Richardson Will Address the Class of 2015
• NYMC Celebrates 27th Annual Employee Recognition Program
• View the NYMC Corporate Citizenship Award Video
• NYMC Ranks in Top Ten Med Schools with the Most Applicants

Prevalence Of School Nurses In Kentucky And Student Outcomes, Teena Darnell

Graduate Theses, Dissertations, and Capstones

Objective: The purpose of this study was to identify whether the presence of a nurse in the public high school setting was associated student outcomes. Data gleaned from the study will be used to enact a new legislative policy mandating the presence of a nurse in all public schools in the state of Kentucky.

Background: Nurses employed in the school setting support both the educational mission of the institution, as well as the health and well-being of students. Studies have explored the relationships between school nurse presence and student health. It has been suggested that when children experience poor …

Maximizing The Speed Of Influence In Social Networks, Yubo Wang

Master's Projects

Influence maximization in social networks is the problem of selecting a limited

size of influential users as seed nodes so that the influence from these seed nodes can propagate to the largest number of other nodes in the network. Previous studies in influence maximization focused on three areas, i.e., designing propagation models, improving algorithms of seed-node selection and exploiting the structure of social networks. However, most of these studies ignored the time constraint in influence propagation. In this paper, I studied how to maximize influence propagation in a given time, i.e., maximizing the speed of influence propagation in social networks. …

Novel Methods Of Disease Surveillance In Wildlife, Cristina M. Hansen

Biological Sciences

Both infectious and noninfectious disease agents in wildlife impact human health and accurate research, monitoring, and diagnostic methods are necessary. The objectives of the research reported here were to develop and implement novel methods for bacterial and toxicological disease agent surveillance in wildlife. This dissertation begins with a review of tularemia, an important zoonotic disease to the state of Alaska and the Northern hemisphere. In chapter two, I show the development and implementation of broad-based PCR and quantitative PCR (qPCR) surveillance methods for bacterial DNA in tissue samples; 1298 tissue samples were assayed, numerous potential bacterial pathogens were identified and …

Ebola Outbreak In Nigeria: Increasing Ebola Knowledge Of Volunteer Health Advisors, Unnati Patel, Jennifer R. Pharr, Chidi Ihesiaba, Frances U. Oduenyi, Aaron T. Hunt, Dina Patel, Michael Obiefune, Nkem Chukwumerije, Echezona E. Ezeanolue

Environmental & Global Health Faculty Research

In many low-income countries, volunteer health advisors (VHAs) play an important role in disseminating information, especially in rural or hard-to-reach locations. When the world's largest outbreak of Ebola virus disease (EVD) occurred in 2014, a majority of cases were concentrated in the West African countries of Guinea, Liberia, and Sierra Leone. Twenty cases were reported in Nigeria initially and there was a need to rapidly disseminate factual information on Ebola virus. In southeast Nigeria, a group of VHAs was being used to implement the Healthy Beginning Initiative [HBI], a congregation based intervention to increase HIV testing among pregnant women and …

Detection Of Hcmv Viral Il-10 (Vil-10) In Healthy Blood Donors, Vivian P. Young

Master's Theses

Human cytomegalovirus (HCMV) is widespread in the general population and can establish lifelong latency with expression of a limited subset of viral genes. The UL111A gene is expressed during both lytic and latent infection, and at least two protein isoforms are produced. During lytic infection, the full length transcript yields cmvIL-10, a potent immunosuppressive viral ortholog of human IL-10 (hIL-10). Alternative splicing of the UL111A transcript yields a truncated protein, LAcmvIL-10, which is expressed during both lytic and latent infection but with a limited range of immunosuppressive functions. The two viral cytokines, collectively termed viral IL-10 (vIL-10), are identical in …