Digital Commons Network^™

Vol. 40, No. 4: Holiday 2015, School Of Medicine & Health Sciences

North Dakota Medicine Archive

No abstract provided.

Teachers' Perceptions Of Multimodal Literacies In Middle School Health Literacy Programs, Cynthia Darlene Jackson-Howard

Walden Dissertations and Doctoral Studies

Health literacy, defined as the ability to understand and use health information to make informed decisions, is critical to maintaining health; however, not all U.S. states mandate strategies to improve adolescents' health literacy. Moreover, many middle school teachers are often unaware of how their roles could improve the health literacy of their students. Multimodal literacies help students to create meaning through viewing print-based resources and using digital technologies. The purpose of this study was to investigate teachers' perceptions of the effectiveness of multimodal literacies on adolescents' overall health literacy via the introduction of health literacy programs into the curriculum. This …

Fda Industry Guidance Targeting Antibiotics Used In Livestock Will Not Result In Judicious Use Or Reduction In Antibiotic-Resistant Bacteria, Sarah Haag

Fordham Environmental Law Review

No abstract provided.

The Effects Of Motility And Chemotaxis On Vibrio Cholerae Colonization In Zebrafish, Paula Dietz

Wayne State University Theses

Vibrio cholerae, the cause of the diarrheal disease cholera, is a gram-negative, curved rod-shaped bacterium, with a single polar flagellum. V. cholerae is naturally found in aquatic environments and is highly motile. When it enters a human host, V. cholerae uses flagellar motility to pass through the stomach and into the small intestine. Once in the small intestine, motility genes are downregulated and virulence gene expression is upregulated. V. cholerae motility and chemotaxis effects have not yet been studied in a zebrafish model, a natural host of this bacterium. We hypothesize that V. cholerae in frame deletions of vital motility …

Prevalence Of Malaria And Glucose-6-Phosphate Dehydrogenase Deficiency In Malaria-Endemic Southwestern Uganda: Implications For Primaquine Use, Michelle Roh

Public Health Theses

Abstract

Introduction: Malaria transmission in Uganda is remarkably heterogeneous, and declines in prevalence have not been uniform. Previous surveys in southwestern Uganda have shown declines in parasite prevalence from 2004 to 2010. As malaria transmission continues to decline in southwestern Uganda, aggressive strategies, such as the addition of primaquine (PQ) to artemisinin-combination therapies (ACTs), are being considered in low transmission settings. Despite the potential benefit of PQ in reducing transmission, concerns over its safety and efficacy have hampered its deployment. In particular, those with glucose-6-phosphate dehydrogenase (G6PD) deficiency are at a higher risk of hemolytic toxicity.

Methods: To better assess …

Cost-Effective Juvenile Justice Reform: Lessons From The Just Beginning “Baby Elmo” Teen Parenting Program, Shani M. King, Rachel Barr, Jennifer Woolard

UF Law Faculty Publications

This Article reviews the literature describing the rise of mass incarceration and its effects on individuals, families, and communities. The Article then describes the Just Beginning “Baby Elmo” Program, a cost-effective, sustainable parental instruction and child visitation intervention created for use with incarcerated teen parents. This intervention is designed to increase the quality of interaction between parent and child, increasing the likelihood that the teen father and child will form a positive relationship and maintain that relationship after release from detention—thereby increasing the child’s resilience and reducing the risk of recidivism for the teen father. The “Baby Elmo” Program is …

Factors Influencing Depression In Men: A Qualitative Investigation, Lori A. Mutiso

Theses and Dissertations--Nursing

The purpose of this qualitative descriptive study is to describe men’s experiences of depression in order to provide direction for future research of the screening, diagnosing, and treatment of men's depression. Previous research indicates that men experience different depressive symptoms than women, and there is a possibility that men's depression is not being adequately captured by current screening standards, which would theoretically lead to a large number of men with unrecognized, undiagnosed, and untreated depression. If this is the case, this may explain the disproportionately low number of men diagnosed with depression compared to women, in contrast to the disproportionately …

Impacts Of Climate, Geography And White-Nose Syndrome Mortality On The Population Genetic Structure And Variation Of Myotis Lucifugus In The Eastern United States, Shannon Marie Dodge Morgan

Legacy Theses & Dissertations (2009 - 2024)

A myriad of biotic and abiotic factors contribute to the fluctuations in geographic range and size of animal populations. In the Nearctic, bat species have experienced drastic historic changes in available habitat due to Pleistocene glaciations, and are recently imperiled by the introduction of a novel fungal pathogen, Pseudogymnoascus destructans within the last decade. Myotis lucifugus in particular has lost 90-95% of the population in the eastern US due to the fungal disease White-Nose Syndrome (WNS). A population decline of this magnitude will likely result in a loss of allelic diversity as a result of a genetic bottleneck. My study …

Untreated Depression In Persons Living With Hiv In Kazakhstan, Dina Terloyeva

Legacy Theses & Dissertations (2009 - 2024)

Objective:This study investigates the occurrence of depressive symptoms among persons living with HIV, and the relationship between depressive symptoms and HIV treatment initiation and adherence.

Antibiotics, The Microbiome, And Immunity : A Case Study In Bangladesh, Carmen Fagnani

Legacy Theses & Dissertations (2009 - 2024)

The purpose of this study was to establish a theoretical impact of antibiotic misuse on the microbiome and its effects on immunity. Recent studies indicate the importance of a microbiome on the immune system. Both the leptin signaling pathways and CD4T cell production are influenced by the microbiome (Mazmanian, et al. 2005). The use of antibiotics has been associated with dysbiosis, a microbial imbalance in the digestive tract. The immune system is limited when the microbiome is dysbiotic.

Francisella Tularensis Catalase Restricts Immune Function By Impairing Trpm2 Channel Activity, Nicole Lynn Flaherty

Legacy Theses & Dissertations (2009 - 2024)

As an innate defense mechanism, macrophages produce reactive species that weaken pathogens and serve as secondary messengers to modify signaling responses involved in immune function. The gram-negative bacterium F. tularensis utilizes its antioxidant armature to limit the host immune response but the mechanism behind this suppression has not been defined. Here we establish that F. tularensis limits Ca2+ entry thereby limiting actin reorganization and IL-6 production in a redox-dependent fashion. Wild-type (LVS) or catalase deficient F. tularensis (∆katG) show distinct profiles in their H2O2 scavenging capacity, 1 pM/sec and 0.015 pM/sec, respectively. Murine alveolar macrophages infected with ∆katG display distinct …

Role Of Antibody Isotypes In Providing Passive Protection Against Ricin Toxin, Ipneet Kaur Dhaliwal

Legacy Theses & Dissertations (2009 - 2024)

Ricin toxin is a glycoprotein produced by the castor bean plant, Ricinus communis. Ricin is an extraordinarily potent inducer of cell death and inflammation, especially following inhalation. The toxin’s enzymatic subunit (RTA) is transported via retrograde transport into the cytoplasm of mammalian cells by the toxin’s B subunit (RTB). Once in the cytoplasm, RTA inactivates ribosomes through cleavage of ribosomal RNA. In this study, I characterized a ricin-specific monoclonal IgA antibody (mAb) known as 23D7. I confirmed that 23D7 reacts with RTA and is effective at neutralizing ricin in a Vero cell cytotoxicity assay in vitro. To localize the epitope …

The Effects Of Landscape On Malaria Vectors Of The Neotropics, William David Lainhart

Legacy Theses & Dissertations (2009 - 2024)

Worldwide malaria control efforts have had varying degrees of success, leaving many countries either eliminating malaria or controlling malaria. In order to maintain forward momentum toward malaria elimination, malaria-eliminating and –controlling countries require different information regarding risk factors, spatial distributions of cases and vectors, vector biology metrics, and vector population genetics. The goal of this dissertation work was to provide information that addresses the knowledge gaps preventing the creation of effective vector and malaria control programs in one malaria-eliminating country (Panama) and two malaria-controlling countries (Peru and Brazil). Case data from Panama were analyzed to assess differences in risk factors …

Evolution Of Viral Host Recognition Through Multiple Pathways, Sara Stark

Legacy Theses & Dissertations (2009 - 2024)

Most viruses are specialists and have a narrow host range, infecting only a single species or host strain. However, many of the viruses currently responsible for causing emerging infectious diseases are generalists and able to infect a wider host range. Viruses that are able to infect multiple hosts are more likely to continue expanding their host range and infecting additional species. The ability to infect a novel host is a complex process. The first step required to acquire the ability to infect a novel host is host recognition; the host recognition binding protein on the virus must be able to …

Trends Of Injecting Risk Behaviors Among People Who Inject Drugs In Ukraine : The Analysis Of Bio-Behavioral Surveillances Conducted In 2007-2013, Iuliia Makarenko

Legacy Theses & Dissertations (2009 - 2024)

Abstract

Assessment Of Quality Of Life (Qol) In People Living With Hiv In Georgia, Ekaterine Karkashadze

Legacy Theses & Dissertations (2009 - 2024)

Background: Identification of factors that influence quality of life (QoL) is important in order to improve health and social care services. No prior research is available on QoL in people living with HIV in the country of Georgia. The purpose of our study was to assess QoL among Georgian HIV-infected individuals and to examine associations of socio-demographic and disease-related factors with general and domain-specific QoL.

Trends In Risky Sexual Behavior Among Men Who Have Sex With Men : Analysis Of Repeated Cross-Sectional Survey Data From Ukraine, 2007-2013, Roksolana Kulchynska

Legacy Theses & Dissertations (2009 - 2024)

Objective: To examine changes in risky sexual behavior over time, i.e., unprotected anal intercourse (UAI) among men who have sex with men (MSM) in Ukraine.

Factors Associated With Solving Pulsed-Field Gel Electrophoresis Clusters In New York State Outside Of New York City, 2008-2012, Madhu Anand

Legacy Theses & Dissertations (2009 - 2024)

Motivation and Rationale

Breastfeeding Initiation, Duration And Exclusivity In New York State : Impact Of Hospital Maternity Care Practices, Hospital Characteristics And Individual/Socio-Demographic Factors, Eileen Mary Fitzpatrick

Legacy Theses & Dissertations (2009 - 2024)

Prevalence of breastfeeding initiation in New York State (NYS) nearly meets Healthy People 2020 goals. Improvements in breastfeeding duration and exclusive breastfeeding (EBF) have lagged behind those achieved for initiation. Implementation of Ten Steps to Successful Breastfeeding in hospital maternity care has improved breastfeeding initiation, duration and exclusivity; but data on the independent association with specific Steps have been equivocal. Utilizing NYS-linked data from the Maternity Practices in Infant Nutrition and Care (mPINC) and the Pregnancy Risk Assessment Monitoring System (PRAMS), the associations of individual maternity care practices/Steps with breastfeeding behaviors were evaluated. Analyses included mothers who participated in PRAMS …

Analysis Of Strategies For Successful Identification, Reporting, And Prevention Of Carbapenem-Resistant Enterobacteriaceae (Cre) In Acute Health Care Facilities In New York State, Christen Leigh Mayer

Legacy Theses & Dissertations (2009 - 2024)

Background

Genome-Scale Analyses Of Transcription And Transcriptional Regulation In Bacteria, Devon Marie Fitzgerald

Legacy Theses & Dissertations (2009 - 2024)

The textbook model of bacterial transcription regulation posits that promoters occur immediately upstream of genes and that transcription factors (TFs) modulate transcription through promoter-proximal binding. However, the recent application of unbiased genome-wide approaches, such as ChIP-seq and RNA-seq, has revealed a much more complex picture, including TF binding and transcription initiation occurring in unexpected locations. This dissertation describes the use of deep sequencing-based approaches to evaluate the genome-wide binding of transcription-related proteins and identify locations of transcription initiation. I have assessed the genome-wide binding of three Escherichia coli TFs and an alternative σ factor. Additionally, I have analyzed genome-wide patterns …

Correlates Of Life-Time History Of Purchasing Sex Services By Men In Saint Petersburg And Leningrad Oblast, Russian Federation, Polina Girchenko

Legacy Theses & Dissertations (2009 - 2024)

Background. Commercial sex workers (CSW) in Russian Federation are at high risk of HIV infection and transmission as a result of unsafe sexual and injecting behaviors. Their clients might be at increased risk of acquiring HIV; however, little is known about the population of men purchasing sex services. This study’s goal is to investigate factors associated with a history of purchasing sex services by men in Saint Petersburg and Leningrad Oblast, Russian Federation.

Evidence Of Son Preference And Resulting Demographic And Health Outcomes In Pakistan, Zeba Sathar, Gul Rashida, Sabahat Hussain, Anushe Hassan

Poverty, Gender, and Youth

Pakistan has a highly patriarchal society. Consequently, the desire for sons is a dominant and widely prevalent cultural value that is reinforced by feudal kinship systems that permeate many parts of the country. While reliance on sons is stronger in rural areas because of agricultural work and the tying of land ownership with male inheritance, even in other areas boys are seen to be important in carrying on the family name and taking care of parents in old age. On the other hand, daughters are seen as an expense and an economic burden in both rural and urban areas. A …

Health Facility Guidelines And Management Benchmarks: Improving Workplace Health Services And Health Management In Factories, Farms And Other Workplaces In Low- And Middle-Income Countries, David Wofford, Marat Yu, Lauren Shields, Maria Pontes

Reproductive Health

This document contains a set of voluntary health and management guidelines for corporations and their supply chains to promote continual improvement and application of good practices, better access to men’s and women’s health services, and more effective use of health resources at workplaces in the developing world. It is focused on both quality of health services provided at the workplace and adequacy of company policies and management systems to ensure that workers have access to health services. The main goals of the guidelines are to: 1) help enterprises—multinational companies and their supplier or subsidiary companies in developing countries—improve the management …

Relevance To Psychology Of Beliefs About Socialism: Some New Research Questions, Bernice Lott

Psychology Faculty Publications

This article aims to stimulate discussion about the potential relevance of the concept of socialism for what we study and the questions we ask. The economic systems of capitalism and socialism are seldom considered subjects of interest in psychology. At this particular time, however, especially in the United States, the relevance of these systems for our theories and research on human behavior, health, and human welfare seem particularly relevant and potentially significant. I argue that discussions of socialism should be helpful in expanding the context of our concerns in psychology and the identification of important new variables. The growing crisis …

Washington University School Of Medicine Bulletin, 2015-2016

Washington University School of Medicine Bulletins

No abstract provided.

Knowledge And Perceptions Of Hpv Vaccine Acceptance Among African-American College Women, Lauren R. Darensbourg, Ivette A. López, Matthew T. Dutton, C Perry Brown

Florida Public Health Review

Human papillomavirus (HPV) is the most prevalent sexually transmitted disease in the United States. Prevalence rates among sexually active young women are approximately 50%. An HPV vaccine has been created that has high efficacy in preventing persistent HPV infection, cervical cancer precursor lesions, and genital warts caused by four HPV subtypes. The purpose of this study was to assess African-American college women’s knowledge and perceptions of HPV, and their association with the acceptance of HPV vaccination. Variable selection was guided by the Health Belief Model and the Theory of Planned Behavior. Written surveys were administered to 122 African-American women between …

Investigating The Regulation Of Alpha-Synuclein Clearance By Alpha-Galactosidase-A In Parkinson Disease, Emily D. Haley, Sonia E. Tse, Hailin Lu, John J. Shacka

Inquiro (undergraduate research journal)

pp. 48-53

https://www.uab.edu/inquiro/images/2016_Issue/Retinitis_Pigmentosa.pdf

Klebsiella Pneumoniae Assimilates To Increasing Concentrations Of Cephalothin By Differential Outer Membrane Porin Expression And Increased Production Of Capsular Polysaccharides, Nghi B. Lam

UNF Undergraduate Capstone Projects and Honors Theses

Klebsiella pneumoniae is an opportunistic Gram-negative nonmotile bacteria that causes nosocomial infections. In these bacteria, nutrients as well as antibiotics are able to diffuse through the outer membrane via outer membrane porins, transmembrane protein channels. Loss of outer membrane porins, increased capsule production, and a highly mucoid phenotype are commonly observed among antibiotic resistant isolates of this pathogen. The goal of this study was to investigate changes in outer membrane porin expression and capsular polysaccharide production by K. pneumoniae as it transitions to a β-lactam antibiotic resistant phenotype. Klebsiella pneumoniae strain 43816, which is susceptible to β-lactam antibiotics such as …

The Genesis And Emergence Of Community-Associated Methicillin-Resistant Staphylococcus Aureus (Ca-Mrsa): An Example Of Evolution In Action?, Alan L. Gillen, Jason Conrad, Michael Cargill

Faculty Publications and Presentations

Staphylococcus aureus infections are a common cause of disease, particularly in colonized persons. Recently, a series of published articles have reported that community-acquired methicillin-resistant S. aureus (CA-MRSA) strains are evolving and increasingly becoming prevalent in households while health care acquired MRSA (HA-MRSA) is declining in the USA. The changing superbugs have often been used as an example of evolution in action. Although MRSA infections have become increasingly reported in the community, population-based studies of students preparing for the health professions having S. aureus and MRSA colonization are lacking. During the 2014–2015 school year 544 students were tested for MRSA carriage …