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Campus Report, Vol. 43, No. 4, University Of Dayton

Campus Report

The publication for faculty and staff of the University of Dayton. This issue includes UD's four year tuition plan, symposium on the stare of race at UD, food desert, VP searches, and top teachers.

Examining Student Course Outcomes In First Year Anatomy And Physiology Using E-Books Versus Traditional Textbooks, Howard Marquise

Theses & Dissertations

Over the last several years, use of e-books in higher education has increased significantly and is projected to continue through the next decade. Institutions of higher learning have implemented use of e-books without any data that verified the impact on student learning outcomes. The purpose of this ex post facto, quantitative study was to compare student learning outcomes in Human Anatomy and Physiology I courses using e-books versus using traditional textbooks at a two-year public community college in South Texas. With a participant population of 686 students, data were analyzed by their final grades comparing the differences between those who …

The Image Machine, Jeremy Min Burns

Architecture Senior Theses

Architecture has always been an image machine. From the Lascaux cave paintings to the Sainte-Chapelle in Paris to the multimedia installations of the Eameses to the early projects of Diller Scofidio, images and architecture have cohabited persistently and productively for centuries. However, since the dawn of the digital age, the ontological status of images has changed; and in turn so has the relationship between images and architecture. Rather than being anchored to a specific material support, images exist as manipulable data. While some have viewed the digital turns as the transcendence of information beyond the human subject, an era of …

Synthesis Of Carbon-11 Labeled Organic Molecules For Pet Studies, So Jeong Lee

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

PET has played a key role in the field of molecular imaging and nuclear medicine over the past decades. PET represents a non-invasive molecular imaging technique to study and visualize human physiology by detecting positron-emitting radiopharmaceuticals labeled with short half-live radioisotopes (i.e. | 11C, 13N, 15O, and 18F) that visualize in vivo biochemical processes and metabolic pathways (i.e. | glycolysis and protein/DNA synthesis). PET is also an emerging method for measuring body function and tailoring disease treatment in living human by detecting biochemical changes preceding anatomical changes occurring a disease. The capability of imaging quantitatively and with high sensitivity without …

The Effects Of Passive, Active, And Beta-Alanine Supplemented Recovery On Blood Lactate During Anaerobic Exercise, Tracey Hampshire

2015 Fall Honors Capstone Projects - Archive

It is widely shown through experimentation and knowledge of human physiology that an active recovery following high-intensity exercise removes lactic acid (BLa) more quickly than passive recovery. Some research suggests that Beta-Alanine (BA) supplementation can decrease BLa levels following supramaximal exercise. The purpose of this study was to assess whether passive, active, or Beta-Alanine supplemented recovery was more effective at lowering BLa accumulation anaerobic exercise. Nine subjects participated in this experiment (one subject was excluded). Each completed three sessions of active, passive, or supplemented Wingate protocols. Results were determined using SPSS (p < 0.05). There was no statistically significant difference between active and passive recovery (p = .292) or between BetaAlanine and placebo groups (p = .962). The results of this study indicated that there were no differences between BLa in passive and active recovery, and no benefits of Beta-Alanine supplementation on BLa accumulation following supramaximal exercise.

Determination Of Total And D-Amino Acid Content In Mice Brain Tissue By Achiral-Chiral Heart-Cutting Two-Dimensional Liquid Chromatography: Diagnostic And Clinical Relevance And A Comparison Between Non-Perfused And Perfused Tissue, Curran Parpia

Chemistry & Biochemistry Theses - Archive

A heart-cutting two dimensional liquid chromatographic method for the quantification of free amino acid enantiomers from mouse brain tissue is demonstrated. Evidence to support the occurrence of D-amino acids in significant concentrations in physiological samples has spurred studies toward the elucidation of their importance and function. In this work, the level and regional distribution of select amino acids were determined by achiral-chiral LC/LC. Additionally, the effect of tissue perfusion on these levels was investigated. The free amino acid extracts were analyzed as their 9-fluorenylmethyloxycarbonyl derivatives and separated in the reverse phase mode on superficially porous C18. In the second dimension, …

Review Of "Race Unmasked: Biology And Race In The Twentieth Century" By M. Yudell, John B. Jenkins

Biology Faculty Works

No abstract provided.

Development And Testing Of Supplemental Materials For An Undergraduate Healthy Food Product Development Curriculum, Breanne Halteman

All Theses

ABSTRACT The goal of this research project was three-fold: (1) to follow up with students who had taken the Applied Interdisciplinary Product Development (AIPD) course two years prior to assess the long-term effect of the course on perceived self-confidence in product development skills, connectedness with the department, and preparedness to enter the industry; (2) to design, implement, and evaluate course materials educating undergraduate students about the subjects of herbs, spices, and sensory science; and (3) to evaluate the success of dissemination of a sophomore-level hybrid course on healthy food product development. A Subject Knowledge Assessment (SKA) was designed to measure …

Systemic Insulin Sensitivity And Skeletal Muscle Akt Signaling In Rats Artificially Selected For Low And High Aerobic Capacity, Kyle Levi Fulghum

Graduate Theses/Dissertations

The mechanism(s) linking physical inactivity, obesity, and type-II diabetes are unclear. I hypothesized low intrinsic aerobic capacity is associated with reduced systemic insulin sensitivity via skeletal muscle insulin signaling. After 34 generations of selective breeding, high aerobic capacity (HCR) rats exhibited an 8-fold increase in running distance vs low aerobic capacity (LCR) rats (n=14 per group). LCR rats had higher rates of weight gain vs HCR (p<0.05) though food consumption was constant (p=0.86) over a 12-week study. Rats were divided into 4 groups: 1) LCR-Sham Surgery, 2) LCR-Catheterization, 3) HCR-Sham Surgery or 4) HCR-Catheterization (n=7 per group). Euglycemic-hyperinsulinemic clamps on catheterized rats tested insulin sensitivity while sham LCR and HCR were used for basal tissue analysis. Plasma insulin levels did not differ during the clamps, but LCR required lower glucose infusion rates than HCR (p<0.05). Upon insulin stimulation, both absolute and normalized phospho-Akt(Ser473) of soleus muscle were significantly increased in HCR above basal group (p<0.05), but not in LCR. No difference was observed between insulin-stimulated phospho-Akt(Ser473) of HCR and LCR groups . These data support that LCR is linked to a reduction in insulin sensitivity in vivo without impairments of insulin-stimulated skeletal muscle phospho-Akt(Ser473) vs HCR rats.

Students' Perception Towards Thermal Sensation In Libraries / Chen Sin Yee, Sin Yee Chen

Student Works (2010-2019)

Recently, the effect of thermal sensation found to greatly impacted on the outcome or productivity of work within an area. Based on the thermal environment data, the air temperature and mean radiant temperature found to be in compliance with the standard stated, but the percentage rate of relative humidity revealed that were higher than standard, whereas the air velocity has reported were lower than standard. On the other hand, the results shown from relevant parameters in perceived thermal sensation, i.e. the level of coldness (air temperature and mean radiant temperature), the level of humidity (relative humidity) and the level of …

Optimization Of Lead Spectinamide Compounds As Novel Anti-Tuberculosis Agents With A Pharmacometric Approach, Ashit Rasendu Trivedi

Theses and Dissertations (ETD)

In an effort to combat the global Tuberculosis pandemic, Dr.Richard E. Lee and his group at St.Jude Children’s Research Hospital designed a novel series of anti-tuberculosis agents, spectinamides – semi-synthetic analogs of spectinomycin. Spectinamides are a potent inhibitor of mycobacterial ribosomes and overcome efflux mediated drug resistance in M. tb. Spectinamides have shown an excellent in vitro activity, which makes them well suited for further lead optimization and preclinical development. We hypothesized that through pharmacokinetic (PK) and pharmacodynamics (PD) model-based dosing optimization studies, we could strategically guide the selection and refinement of more potent and effective anti-TB spectinamides. Biopharmaceutical in …

The Color Of The Year: A Textual Analysis Of Pantone’S Color Communication Techniques Through The Application Of Barthes’ Semiotic, Kyung Lee

Masters Theses

This research analyzes the content of Pantone’s color of the year in 2000, 2002, 2009, 2014 and 2015 utilizing Barthes’ semiological system from a communication perspective. This study scrutinizes the announcement of Pantone’s color of the year as well as its color story to discover the purpose and the effectiveness of the verbalized nomination. The result reveals the significance of the semantic nature, which directs individuals’ viewpoint and creates a new connotation to alter their preconception. Also, Pantone’s color of 2014, Radiant Orchid, verified that the consolidation of the visual image and verbal content can maximize the influences that the …

Influence Of Lactobacillus Rhamnosus Isolated From “Amabere Amaruranu” Cultured Milk On Adipogenesis, Justin E. Kotala

Electronic Theses and Dissertations

This study was performed to test the in vitro effects of a Lactobacillus rhamnosus isolate from “amabere amaruranu”, a traditional Kenyan cultured milk, on 3T3-L1 and Caco-2 cell lines. Cultures of fully mature 3T3-L1 adipocytes were treated with bacterial isolate cell extract (CE), filtered spent broth (FSB) from overnight bacterial culture, or with a PBS control. Expression levels of PPAR³1 and 2, C/EBP±, and ATGL proteins in 3T3-L1 cells were upregulated by FSB treatment. CE treatment did not affect protein expression levels. Expression of MTTP and SREBP-1c proteins in Caco-2 cells showed no change with either treatment. Optical density measurements …

Screening Bioactive Molecules In Tetrahymena Thermophila Using Phagocytosis Determined By Flow Cytometry, Santosh Gummidipundi

Master's Theses

The evaluation of molecules that have potentially bioactive significance is an expanding field, but current screening assays are expensive and time consuming. Mammalian cell-based assays require aseptic techniques, complex media and long generation times. This thesis reports on an assay that incorporates Tetrahymena phagocytic ingestion and flow cytometry to evaluate several potentially bioactive molecules. Several factors that influenced optimal and reproducible results were analyzed. Seven potentially bioactive molecules (serotonin, norepinephrine, dopamine, morphine, colchicine, mexiletine and procainamide) were evaluated to determine their effect on phagocytosis by Tetrahymena. Assay results indicated that the phagocytic rate was unaffected by serotonin, norepinephrine, dopamine, and …

The Role Of Nitric Oxide In Skeletal Simulated Microgravity Response, Luan Tran

Master's Theses

Prolonged exposure to the space environment leads to bone loss. Using a ground-based model for microgravity (hind-limb unloading), it has been shown in rodents that proliferation and differentiation activity of osteoprogenitors are decreased with exposure to simulated microgravity (Kostenuik et al., 1997). Osteoblast mineralization activity has been shown to increase with nitric oxide supplementation (Afzal et al., 2004; Koyama et al., 2000). I hypothesized that the degenerative effects of microgravity exposure result from chronic changes in nitric oxide regulation in osteoprogenitors, and that supplementation with exogenous nitric oxide following exposure would ameliorate these changes. In 20 C57Bl/6 mice, hind-limb unloading …

Efficacy Of Galactooliosaccharide (Gos) And/Or Rhamnose-Based Synbiotics In Enhancing Ecological Performance Of Lactobacillus Reuteri In The Human Gut And Characterization Of Its Gos Metabolic System, Monchaya Rattanaprasert

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Probiotic L. reuteri has potential to produce antimicrobial compounds and secrete immunosuppressive factors. These metabolic attributes could benefit the human host by providing colonization resistance (competitive and metabolic exclusion) against enteropathogens and mitigating inflammation. As metabolically active cells are fundamental to such probiotic properties, synbiotic approaches that supply L. reuteri with a source(s) of carbon, energy, and/or external electron acceptor for cell growth in the gut environment could therefore prompt the probiotic to engage in beneficial activities. In this study, the efficacy of GOS and/or rhamnose-based synbiotic approaches in promoting colonization persistence and metabolic activity of L. reuteri was evaluated. …

Context Construction Through Material Perceptions: Experiences From An Explorative Workshop, Riikka Townsend, Salu Ylirisku

Experiential Knowledge (EKSIG) Conference Series

This paper describes and reflects upon a design-led workshop carried out by design and science researchers in an interdisciplinary material development project. The aim of the workshop was to construct application context for the design of thermoelectric energy harvesting applications that combine textiles, thermoelectric materials, electronics, and additional smart materials. The experience of textiles is typically multi-sensorial as textiles are often close to the body or in the touching proximity to people. However, the development of novel textile materials and applications is often science-led resulting in extensive considerations of technical aspects at the cost of the experiential insights. The workshop …

Assessing A Monitoring Scale Of Physiological Health And Risk Assessment Among Those Exposed To Heated Environments: A Brief Report, Corey A. Peacock, Ellen L. Glickman, Gabriel J. Sanders, Yong Suk Seo, Brandon S. Pollock, Keith J. Burns, Lynn Kakos, John Gunstad

Journal of Human Performance in Extreme Environments

Background: Prevention of heat illness is of considerable medical interest within the field of occupational work. There are many established methods of perceptual health assessment; however, many are rather unpractical and timely. The objective was to improve the practicality and timeliness of perceptual physiological monitoring; a Heat Thermal Sensation scale has been developed. The usefulness of the scale was assessed on its ability to monitor physiological variable. Materials and Methods: Ten apparently healthy individuals performed physically exerting activity while exposed to 37 °C. Sensation and physiology were measured throughout. Results: The perceptual monitoring scale demonstrated weak positive correlations with human …

Safe Operations Above Fl600, Lt. Col. Stephen Hunter

Space Traffic Management Conference

Safe Operations Above FL600

Abstract

With the increase in likelihood of near-term development of revenue-generating point-to-point suborbital flights and the increase in high-altitude-long-endurance commercial operations above FL600, the criticality of addressing operations above class A airspace has never been more pressing. While the Federal Aviation Administration describes the National Airspace System, it doesn’t offer a description that includes a top. Technological, physiological, physical and administrative limitations have relegated most air operations to FL600 and below. As that changes, previous work on Space Traffic Management (STM) concepts begin to take on new life and add to sincere considerations for adaptation or …

Prediction: The Quintessential Model Validation Test, Wayne Wakeland

Systems Science Friday Noon Seminar Series

It is essential to objectively test how well policy models predict real world behavior. The method used to support this assertion involves the review of three SD policy models emphasizing the degree to which the model was able to fit the historical outcome data and how well model-predicted outcomes matched real world outcomes as they unfolded. Findings indicate that while historical model agreement is a favorable indication of model validity, the act of making predictions without knowing the actual data, and comparing these predictions to actual data, can reveal model weaknesses that might be overlooked when all of the available …

Caribou, Petroleum, And The Limits Of Locality In The Canada–Us Borderlands, Jenny Kerber

English and Film Studies Faculty Publications

his article discusses Karsten Heuer’s 2006 book Being Caribou in light of debates in ecocriticism and border studies about how to define the local in the context of environmental problems of vast range and uncertain temporality. It explores how Heuer’s book about following the Porcupine Caribou herd’s migration engages in multiple forms of boundary crossing—between countries, between hemispheric locations, and between species—and shows how insights from Indigenous storytelling complicate the book’s appeal to environmentalist readers by asserting a prior, transnational Indigenous presence in the transboundary landscapes of present-day Alaska and the Yukon.

The Flaws And Human Harms Of Animal Experimentation, Aysha Akhtar

Experimentation Collection

Nonhuman animal (“animal”) experimentation is typically defended by arguments that it is reliable, that animals provide sufficiently good models of human biology and diseases to yield relevant information, and that, consequently, its use provides major human health benefits. I demonstrate that a growing body of scientific literature critically assessing the validity of animal experimentation generally (and animal modeling specifically) raises important concerns about its reliability and predictive value for human outcomes and for understanding human physiology. The unreliability of animal experimentation across a wide range of areas undermines scientific arguments in favor of the practice. Additionally, I show how animal …

The Flaws And Human Harms Of Animal Experimentation, Aysha Akhtar

Morality and Ethics of Animal Experimentation Collection

Nonhuman animal (“animal”) experimentation is typically defended by arguments that it is reliable, that animals provide sufficiently good models of human biology and diseases to yield relevant information, and that, consequently, its use provides major human health benefits. I demonstrate that a growing body of scientific literature critically assessing the validity of animal experimentation generally (and animal modeling specifically) raises important concerns about its reliability and predictive value for human outcomes and for understanding human physiology. The unreliability of animal experimentation across a wide range of areas undermines scientific arguments in favor of the practice. Additionally, I show how animal …

We Are… Bridging Medicine And Science, Vol. 1, Issue 4, Fall 2015, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

No abstract provided.

The Fight Master, Fall 2015, Vol. 37 Issue 2, The Society Of American Fight Directors

Fight Master Magazine

No abstract provided.

Focus On Boise State University, Sherry Squires (Editor)

FOCUS on Boise State

No abstract provided.

University Of Nebraska At Omaha Biomechanics Annual Report, Fall 2015, Biomechanics Research Building

Biomechanics Annual Report

This annual report includes:

Letter from the Director; B.S. in Biomechanics; QLI Partnership

Center for Research in Human Movement Variability: Formation of the Center; Breathing and Walking Coupling Variability in COPD; Gait Variability in Patients with Peripheral Arterial Disease; Development of Postural Control Variability in Autism; The Effects of Virtual Reality on Gait Variability After Stroke; Pilot Grants; COBRE Research Day; New Hires in the Center

Updates: Why Choose the BRB? Where Are They Now? From the Bench to the Market: New Partnership Paves the way to Pre-Symptomatic Disease Detection; Fun Facts; New Quipment

Other Projects: Space Navigation; Neuroscience; Prosthetics; …

Characterization Of Inhibitors Of Fatty Acid Transport Protein-2 In Cell And Animal Models, Nipun Saini

Department of Biochemistry: Dissertations, Theses, and Student Research

Obesity is correlated with insulin resistance and elevated levels of glucose, triglycerides and free fatty acids in blood. This affects overall metabolism and leads to disease. In the obese state, fat also accumulates in non-adipose tissue including liver, muscle and pancreas, where it can lead to cellular dysfunction and death. Currently, only a limited number of drugs are available to combat obesity and it is clear that new drugs, which more narrowly target the metabolic pathways involved, are required. Fatty Acid Transport Proteins (FATPs) are bifunctional proteins involved in the uptake and activation of fatty acids by esterification with coenzyme …

Seeing Your Face Is Not Enough: An Inertial Sensor-Based Liveness Detection For Face Authentication, Yan Li, Yingjiu Li, Qiang Yan, Hancong Kong, Robert H. Deng

Research Collection School Of Computing and Information Systems

Leveraging built-in cameras on smartphones and tablets, face authentication provides an attractive alternative of legacy passwords due to its memory-less authentication process. However, it has an intrinsic vulnerability against the media-based facial forgery (MFF) where adversaries use photos/videos containing victims' faces to circumvent face authentication systems. In this paper, we propose FaceLive, a practical and robust liveness detection mechanism to strengthen the face authentication on mobile devices in fighting the MFF-based attacks. FaceLive detects the MFF-based attacks by measuring the consistency between device movement data from the inertial sensors and the head pose changes from the facial video captured by …

Recognizing Occupational Stress: A Case Study Of Admission Staff In A For-Profit Nursing College, Carie L. Powers

All Theses And Dissertations

While numerous studies have looked at the influence of occupational stress on employees, less is known about the effects on employees in the for-profit higher education industry. Admissions advisors in particular must endure cyclical pressures to fill classes to ensure a college’s financial viability. A criterion sample of 12 admissions advisors employed at a for-profit nursing college with campuses located throughout the United States were interviewed. The participant criterion sample specifically sought to include advisors who enroll pre-licensure nursing degree-seeking students.

The purpose of the study was to acquire a richer understanding of nursing admissions advisors’ convergence of personal recognition …