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Measurement, Modeling, And Mitigation Of Lead Impacts From General Aviation, Stephen Neil Feinberg

McKelvey School of Engineering Graduate Student Theses & Dissertations

Airborne lead (Pb) has been regulated as a criteria pollutant by the United States Environmental Protection Agency (EPA) since the Clean Air Act and its amendments in the 1970s. During the 1970s, atmospheric Pb emissions were dominated by the combustion of leaded automobile fuel and metals manufacturing. Over time, those emissions have decreased greatly and according to the EPA the largest emitter of Pb today is piston-engine aircraft. Additionally, in 2008 the EPA reduced the National Ambient Air Quality Standard (NAAQS) for Pb by an order of magnitude. These combined factors served as the impetus for further study of general …

Cyber-Physical Co-Design Of Wireless Control Systems, Bo Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Wireless sensor-actuator network (WSAN) technology is gaining rapid adoption in process industries because of its advantages in lowering deployment and maintenance cost in challenging environments. While early success of industrial WSANs has been recognized, significant potential remains in exploring WSANs as unified networks for industrial plants.

This thesis research explores a cyber-physical co-design approach to design wireless control systems. To enable holistic studies of wireless control systems, we have developed the Wireless Cyber-Physical Simulator (WCPS), an integrated co-simulation environment that integrates Simulink and our implementation of WSANs based on the industrial WirelessHART standard. We further develop novel WSAN protocols tailored …

Segmentation And Strain Mapping Of A Beating Heart, Kenna Middleton

McKelvey School of Engineering Graduate Student Theses & Dissertations

Conventional methods of estimating deformation optically often compare image intensities before and after deformation to help estimate the strain fields. However, these current meth ods often introduce undesirable error that propagates through the system, growing larger through each strain calculation. These errors create false, concentrated regions of strain throughout the image. Additionally, gathering and evaluating images in three- and four dimensional space creates even more difficulty for conventional methods. Here, by imple menting new techniques of gathering four-dimensional ultrasound data sets and calculating deformation fields with traditional errors reduced three-fold, four-dimensional images were evaluated to create a novel visualization tool …

Novel Applications Of Electrostatic Precipitators In Coal - Biomass Combustion Systems, He Jing

McKelvey School of Engineering Graduate Student Theses & Dissertations

Pulverized coal combustion is an important source of electricity production worldwide. However, it is also a primary air pollution emission (particulate matters, mercury, etc.) source. Electrostatic precipitators (ESPs) are widely used in coal-fired power plants to control particulate matters. This dissertation contributes in the study of the pollution formation from coal combustion processes and pollution control based on ESPs in the following three aspects: (1) explore novel applications of ESPs in particulate matters and mercury removal; (2) develop and evaluate an compact electrostatic precipitator for sampling purpose, which can support offline fly ash particle analysis; (3) study the submicrometer particle …

Understanding The Nano- And Macroscale Processes Impacting Arsenic Mobilization During Managed Aquifer Recharge Using Reclaimed Wastewater, Chelsea Wren Neil

McKelvey School of Engineering Graduate Student Theses & Dissertations

Managed aquifer recharge (MAR) utilizing reclaimed wastewater is a vital means of replenishing natural freshwater supplies in order to meet growing demands. Unfortunately, this process has been found to induce unfavorable geochemical reactions which mobilize arsenic from aquifer sediments. This process is further complicated by the simultaneous formation of iron(III) (hydr)oxide secondary minerals, which can sorb aqueous arsenic. It is crucial to fully elucidate these physico-chemical processes in order to establish safe MAR operations which minimize arsenic release. Thus, the mechanisms controlling arsenic release from arsenopyrite during MAR were investigated from the nano- to macroscale.

First, nanoscale iron(III) (hydr)oxide nucleation …

Molecularly Targeted Nanoparticles For Modulation Of Inflammatory Mediators In Atherosclerosis, Rohun Udatta Palekar

McKelvey School of Engineering Graduate Student Theses & Dissertations

The enzyme thrombin has been demonstrated through experimental and clinical studies to play a crucial role in mediating both inflammation and thrombosis in atherosclerosis. The cellular effects of thrombin in promoting atherosclerosis involve the activation of signaling pathways that result in the secretion of a host of various chemokines, cytokines, cell adhesion molecules, etc. that promote vascular inflammation. Due in part to thrombin and other pro-atherogenic molecules, this prolonged inflammatory state in atherosclerosis results in the deterioration of the endothelium, increasing the risk of focal thrombosis. Current treatment strategies to address the role of thrombin in atherosclerosis, despite efficacy of …

Ion Selectivity And Allostery In The Nak Channel, Joshua B. Brettmann

Arts & Sciences Graduate Student Theses and Dissertations

Ion channels require proper ion selectivity and regulated gating in order to perform their cellular functions. Bacterial ion channels serve as excellent model systems to study structure/function relationships concerning the fundamental processes of ion selectivity and gating. NaK, a non-selective cation channel from Bacillus cereus, has the conserved pore structure of K+ channels. However, its non-canonical selectivity filter structure leads to non-selectivity between Na+ and K+. Full selectivity is restored with two mutations that lead to the restoration of a Kcsa-like selectivity filter structure. Many mutations can be made to the selectivity filter of NaK without loss of protein stability …

Lysosomal Rnaset2 Is Required For Metabolic Stress-Mediated Ros Generation And Cell Death, George Caputa

Arts & Sciences Graduate Student Theses and Dissertations

Ectopic lipid deposition in non-adipose tissues is a hallmark of metabolic diseases, such as obesity and diabetes, and associated with cell dysfunction, cell death, and organ dysfunction. However, the molecular mechanisms linking excess free fatty acid to cell death are poorly understood. In order to identify genes critical for lipotoxicity, our lab performed a genetic screen in Chinese hamster ovary cells and isolated mutants that were resistant to lipotoxic death. In one of the lines, mutant 2B1, an allele encoding RNASET2, a ribonuclease of the T2 family, was disrupted by proviral insertion. We found that RNASET2 is induced during lipotoxicity …

Characterizing The Role Of Sialylated Milk Glycans And The Infant Gut Microbiota In Growth And Metabolism, Mark Richard Charbonneau

Arts & Sciences Graduate Student Theses and Dissertations

Undernutrition is a pressing and pervasive global health problem. The pathogenesis of this disease remains unclear, but epidemiologic studies indicate that it is not due to food insecurity alone. Moreover, current therapeutic interventions have limited efficacy in preventing or ameliorating the long-term sequelae of undernutrition, including stunting and cognitive deficits. Recent culture-independent studies have demonstrated that the normal postnatal pattern of gut microbiota development is disrupted in children with undernutrition, leading to the proposal that perturbations in gut microbiota development impairs healthy growth of the host. Human breast milk contains a diverse repertoire of free and conjugated human milk oligosaccharides …

The Identification Of Alkaloid Pathway Genes From Non-Model Plant Species In The Amaryllidaceae, Matthew B. Kilgore

Arts & Sciences Graduate Student Theses and Dissertations

Secondary metabolites are often restricted in their distribution to different groups of organisms. For this reason, attempts to study these often useful and interesting products of metabolism require an ability to work in a diversity of non-model species. Methods for gene discovery with low investment and high efficiency are needed to effectively identify the biosynthetic genes in these diverse pathways. During this work, a workflow for efficiently identifying biosynthetic genes was developed and applied to Amaryllidaceae alkaloid biosynthesis. Genes discovered during this work include a norbelladine 4’-O-methyltransferase, a cytochrome P450 capable of phenol-phenol coupling 4’-O-methylnorbelladine to noroxomaritidine, and a short-chain …

Molecular Mechanisms Of Axon Growth And Regeneration, Dana Watt

Arts & Sciences Graduate Student Theses and Dissertations

Neurons are cells with unique and extremely polarized morphologies. The axon allows communication between the cell soma and the distantly located synaptic terminal and can extend up to one meter in humans. This exceptional cellular structure therefore has specialized biological processes dedicated to its growth, maintenance and regeneration. The structure that carries out axon elongation during development and regeneration is the growth cone, which features a cytoskeletal structure that is both highly dynamic yet consistent in overall organization. The growth cone coordinates a leading edge of dynamic actin with the microtubules of the growing axon, enabling directed outgrowth while maintaining …

Collective Action Dynamics In Urban Neighborhoods: A Study Of Urban Community Gardens, Nishesh Chalise

Arts & Sciences Graduate Student Theses and Dissertations

Lessons from various policies and programs both in the United States and international development have led to a knowledge base concluding that an engaged community is a critical component for developing a thriving community. This is based on a premise that even in the modernized world community still has a role to play along with government and the market in their own development. Community’s role is further highlighted in areas such as low-income urban neighborhoods where both the government and the market may not be able to fulfill all the needs.Research has followed by trying to understand why people engage …

The Role Of Trauma And Mental Health Problems In The Perpetration Of Intimate Partner Violence In Post-Genocide Rwanda, Sarah Myers Tlapek

Arts & Sciences Graduate Student Theses and Dissertations

Exposure to political violence or war is associated with intimate partner violence (IPV) in post-conflict settings (Clark et al., 2010; Gupta, Reed, Kelly, Stein, & Williams, 2012), and civilians and veterans who develop posttraumatic stress disorder (PTSD) after exposure to combat or violence are more likely to perpetrate violence against an intimate partner (Taft, Watkins, Stafford, Street, & Monson, 2011). Rwandan health professionals estimate that after the 1994 genocide more than one-quarter of the country’s population now suffers from PTSD (Munyandamutsa, Nkubamugisha, Gex-Fabry, & Eytan, 2012). Although the majority of Rwandan women (56%) have experienced IPV in their lifetime (National …

Factors Associated With Tonic-Clonic Seizures In Patients With Drug-Resistant Mesial Temporal Epilepsy., Ali Akbar Asadi-Pooya, Cyrus Rostami, Amin H. Rabiei, Michael R. Sperling

Department of Neurology Faculty Papers

PURPOSE: Among different seizure types, tonic-clonic seizures are more significant because they are more often associated with morbidity. No prior study has been done to investigate risk factors associated with tonic-clonic seizures in patients with mesial temporal epilepsy.

METHODS: In this retrospective study, all drug-resistant mesial temporal epilepsy patients in the database of patients who underwent epilepsy surgery at Jefferson comprehensive epilepsy center were recruited. These patients were prospectively registered in a database from 1986 till 2014. Patients' age, gender, epilepsy risk factors, age at seizure onset, and preoperative seizure type(s) were registered routinely. Potential risk factors associated with experiencing …

Reducing The Risk Of Suicide On An Inpatient Acute Behavioral Health Unit, Thomas I. Coleman Mr

Master's Projects and Capstones

Evidence suggest for those who have successfully committed suicide in the form of asphyxiation inside locked facilities are more than likely due to patient bathroom doors. The current unit consists of 30 inpatient medical-psychiatric beds serving the adult and geriatric populations. The goal is to ensure patient safety by removing patient bathroom doors and replacing them with breakaway shower curtains for those exhibiting direct signs and symptoms of suicidal ideations with a plan. The specific aim is to improve patient outcomes by decreasing the number of deaths or attempted suicides. With great results, this type of project has been implemented …

Micro-Determinants Of Income Inequality And Consumption In Rural Bangladesh, S Rahman

School of Engineering, Computing and Mathematics

The paper examines the extent to which household and regional characteristics influence income inequality and consumption/welfare based on an in-depth survey of 406 households from 21 villages in three regions of Bangladesh. Results show that the overall Gini coefficient for rural incomes is 0.43 but Gini-decomposition revealed that the contribution of mixed crop production to inequality is just 10 percent while “Green Revolution” technology contributes almost 29 percent. Land ownership, farm capital assets, modern irrigation, non-agricultural income, and household head”s education significantly increase consumption. Tenants and households with more dependents are doubly disadvantaged and consume significantly less. Regional factors also …

Antisense Rna-Mediated Epigenetic Regulation Of Brain-Derived Neurotrophic Factor., Roya Pedram Fatemi

Open Access Dissertations

Long noncoding RNAs (lncRNAs) regulate chromatin remodeling through their interactions with epigenetic enzymes during development and disease. The inhibition of the natural antisense transcript of Brain-derived neurotrophic factor (BDNF-AS), results in BDNF promoter de-repression and transcriptional upregulation, both in vitro and in vivo. Recently, we showed that BDNF-AS interacts with the histone methyltransferase enhancer of zeste homolog 2 (EZH2) to suppress BDNF mRNA and protein expression. BDNF is an important neurotrophin that is required for neural development and maintenance of the nervous system. Dysregulation of BDNF occurs in a number of neurological disorders, including: Alzheimer’s Disease, Parkinson’s Disease, Rett syndrome, …

A Dynamic Adaptive Simulations Approach For Microgrid Control And Optimization, Aristotelis E. Thanos

Open Access Dissertations

During the past two decades, the power systems witnessed vital changes in terms of centralized paradigm versus more decentralized and market driven approaches; technical advances on communications and computation; and generation technologies which collectively lead to the advancement of microgrids (MGs). In this thesis, a novel dynamic adaptive simulations (DAS) approach is introduced for addressing major challenges in the operation and control of MGs, such as solving the economic and environmental load dispatch problem, achieving a sophisticated autonomous control of microgrids, and promoting the cooperation between individual microgrids to increase the power network reliability and energy surety. Initially, a first …

What's Happening: December 14, 2015, Maine Medical Center

What's Happening

No abstract provided.

Columbia Chronicle (12/14/2015)

Columbia Chronicle

Student newspaper from December 14, 2015 entitled The Columbia Chronicle. This issue is 40 pages and is listed as Volume 51, Issue 15. Cover story: "NFL Draft punts graduation back to The Chicago Theatre" Editor-in-Chief: Kyra Senese

Impact Of Working Alliance On Clinical Outcomes In Veterans Enrolled In Suicide-Specific Group Therapy, Brittany N. Groh

Mahurin Honors College Capstone Experience/Thesis Projects

Suicide is a global issue that has led researchers to seek interventions that will have a significant impact on mental health and wellbeing. Veterans comprise the largest number of suicides annually compared to other groups. There is a higher prevalence of mental disorders due to combat related experiences that may play a role in increased rates of suicide. Examined clinical diagnoses in this study include posttraumatic stress disorder (PTSD), depression, alcohol use and substance use. This study explores how group therapy and working alliance play a role in reducing suicidality in a group therapy setting. The first hypotheses is that …

Backwards In High Heels: Examining The Careers And Artistic Contributions Of Fred Astaire’S Female Dance Partners, Fiona Mowbray

Mahurin Honors College Capstone Experience/Thesis Projects

This project examines the careers and contributions of three of Fred Astaire’s female dancing partners during the golden age of movie musicals: Ginger Rogers, Vera-Ellen, and Cyd Charisse. These women receive less recognition than their male co-star, due in part to the political and social environment from the 1930s to the 1950s in America, sexism and competition within Hollywood, and personal obstacles. Rogers, Vera-Ellen, and Charisse are all important as individual performers as well as for the part they played in enhancing Astaire’s legacy. My goal is to bring these women back into the musical theatre narrative in a compact …

Women’S Perceptions Of Muscular Body Image And Its Impact On Eating Disorders, Juliana Eovino

Mahurin Honors College Capstone Experience/Thesis Projects

According to the National Association of Anorexia Nervosa and Associated Disorders (ANAD, 2015), the largest majority of people with an Eating Disorder (ED) are female college aged students. The current study suggests this is due to the differences in society’s portrayal of gender. Media suggests women should strive for a thinness that is unrealistic and unattainable for most women. Participants for the current study take two surveys at separate times to measure how media portrayals of the female body affects eating disorders. The surveys are made up of either a media influence stressing the importance of muscularity or a thinness …

Puerto Rico’S Community Health Centers In A Time Of Crisis, Peter Shin, Jessica Sharac, Marie Nina Luis, Sara J. Rosenbaum

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

In 2014, Puerto Rico’s twenty federally funded community health centers, operating in 71 sites located throughout the Commonwealth, served 330,736 patients, approximately one in ten Commonwealth residents. Compared to other Puerto Rico residents, health center patients are less likely to be insured. Despite considerable growth in Medicaid as a result of the supplemental funding provided under the Affordable Care Act, in 2014, 12.2% of health center patients remained uninsured.

Compared to health centers outside Puerto Rico, Puerto Rico’s health centers show a greater proportion of Medicaid patients served (69% compared to 46% outside Puerto Rico), a greater dependence on physician …

Faculty Senate Executive Committee Minutes, December 14, 2015, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• USUSA No-Test Week Policy – Trevor Olsen
• USUSA Academic Senate Charter Changes – Trevor Olsen
• Conflict of interest with Faculty who have relatives in their class – Ronda Callister
• Focus group regarding frequency of campus wide emails – Ronda Callister
• EPC Monthly Report Items – Larry Smith
• Council on Teacher Education Report – Francine Johnson
• Scholarship Advisory Board – Taya Flores
• 405.12.1 Annual Review of Faculty (First Reading) – Jerry Goodspeed

Faculty Senate Executive Committee Agenda, December 14, 2015, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• EPC Items December 2015
• Council on Teacher Education Report
• Scholarship Advisory Board
• 405.12.1 Annual Review of Faculty (First Reading)

Equip Healthcare: An Overview Of A Multi-Component Intervention To Enhance Equity-Oriented Care In Primary Health Care Settings, Annette J. Browne, Colleen Varcoe, Marilyn Ford-Gilboe, C. Nadine Wathen

Nursing Publications

Background: The primary health care (PHC) sector is increasingly relevant as a site for population health interventions, particularly in relation to marginalized groups, where the greatest gains in health status can be achieved. The purpose of this paper is to provide an overview of an innovative multi-component, organizational-level intervention designed to enhance the capacity of PHC clinics to provide equity-oriented care, particularly for marginalized populations. The intervention, known as EQUIP, is being implemented in Canada in four diverse PHC clinics serving populations who are impacted by structural inequities. These PHC clinics serve as case studies for the implementation and evaluation …

Programming Guide - 333 Golden Gate, Mkthink

Long Range Campus Planning Archive

No abstract provided.

Lrcp Initial Study, Uc Hastings College Of The Law

Long Range Campus Planning Archive

No abstract provided.

Scope Of Work, Trc

Long Range Campus Planning Archive

No abstract provided.