Digital Commons Network^™

Beyond The One-Locus-One-Mirna Paradigm: Microrna Isoforms Enable Deeper Insights Into Breast Cancer Heterogeneity., Aristeidis G Telonis, Phillipe Loher, Yi Jing, Eric R Londin, Isidore Rigoutsos

Computational Medicine Center Faculty Papers

Here we describe our study of miRNA isoforms (isomiRs) in breast cancer (BRCA) and normal breast data sets from the Cancer Genome Atlas (TCGA) repository. We report that the full isomiR profiles, from both known and novel human-specific miRNA loci, are particularly rich in information and can distinguish tumor from normal tissue much better than the archetype miRNAs. IsomiR expression is also dependent on the patient's race, exemplified by miR-183-5p, several isomiRs of which are upregulated in triple negative BRCA in white but not black women. Additionally, we find that an isomiR's 5' endpoint and length, but not the genomic …

Tuberculosis And Cardiovascular Disease: Linking The Epidemics, Moises A. Huaman, David Henson, Eduardo Ticona, Timothy R. Sterling, Beth A. Garvy

Microbiology, Immunology, and Molecular Genetics Faculty Publications

The burden of tuberculosis and cardiovascular disease (CVD) is enormous worldwide. CVD rates are rapidly increasing in low- and middle-income countries. Public health programs have been challenged with the overlapping tuberculosis and CVD epidemics. Monocyte/macrophages, lymphocytes and cytokines involved in cellular mediated immune responses against Mycobacterium tuberculosis are also main drivers of atherogenesis, suggesting a potential pathogenic role of tuberculosis in CVD via mechanisms that have been described for other pathogens that establish chronic infection and latency. Studies have shown a pro-atherogenic effect of antibody-mediated responses against mycobacterial heat shock protein-65 through cross reaction with self-antigens in human vessels. Furthermore, …

Efficacy Of Plant-Derived Antimicrobials In Reducing Foodborne Pathogens In Agricultural Soil And Their Effect On Soil Nutrients And Microbiome, Samantha M. Fancher

Master's Theses

Bacterial pathogens, such as Salmonella and Listeria monocytogenes, can contaminate agricultural soil thereby increasing the risk of produce-associated foodborne outbreaks. In this study three plant-derived antimicrobials (PDAs), carvacrol (CR), thymol (TY), and β-resorcylic acid (BR) were analyzed for their efficacy in reducing Salmonella and L. monocytogenes in agricultural soil. The effect of the PDAs on the soil pH, nutrients, and microbiome was also determined.

Sandy loam soil was inoculated with either Salmonella or L. monocytogenes followed by the addition of 0.25 or 0.5% CR, TY, and BR. The treated samples were analyzed up to 21 days for surviving pathogens. …

2015-October-30-Students Visit Youth To Talk Stress, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Applying Voronoi Tessellations As A Non-Orthogonal Grid Methodology To Inform Public-Private Mix Efforts In Nigeria: An Examination Of The Distribution Of Private Healthcare Providers In Six States And The Covariates Underlying Their Utilization, Trinadh Dontamsetti

USF Tampa Graduate Theses and Dissertations

TB care and prevention is led by the public sector, but many TB symptomatics first seek care in the private sector, highlighting the importance of engaging these facilities. This report examines basic TB epidemiology (such as the gap in case finding that could be addressed in part via private sector activities), health-seeking behaviors (HSB) and diagnostic delays, the size of the private sector, activities of professional societies, and financing. It examines the potential utility of integrating Voronoi tessellations as a GIS-based method for informing and improving Public-Private Mix (PPM) efforts throughout six states in Nigeria. Further, it explores a potential …

Work Overload And Turnover Intention Of Junior Auditors In Greater Jakarta, Indonesia, Andika Pradana, Imam Salehudin

The South East Asian Journal of Management

This paper aims to analyze how work overload influences turnover intentions of newly hired junior auditors in public accounting offices. Job satisfaction, work related stress and work life conflicts are used as mediating variables between work overload and turnover intention. This study employed 141 auditors from several accounting firms operating in the Greater Jakarta region. The sample was selected using purposive sampling. Three mediation hypotheses were tested using Structural Equation Modeling (SEM). The results show that work overload has a significant effect on increasing turnover intention through both job satisfaction and work related stress. In comparison, work overload does not …

Crucial Dimension In Organization Management Of Indonesian Islamic Almsgiving (Zakah) Institutions: Insights For Community Economic Empowerment, Sari Viciawati Machdum, Sri Daryanti, Johanna Debora Imelda, Isbandi Rukminto Adi

The South East Asian Journal of Management

This research analyzed the crucial management dimensions or key elements oforganizations that have been managed as Islamic almsgiving institutions (zakahfunds) in Indonesia. Zakah funds are traditionally managed for a limited number ofbeneficiaries. Zakah funds are now collected and managed by professional Islamicor faith-based organizations and institutions at the national or regional level toachieve a wider range of beneficiaries. This article examines how two Islamicor faith-based organizations, herein named CV (commanditaire vennootschap)“X” and “Y” Foundation, manage small enterprise programs based on zakah toreach a wider range of beneficiaries. Using qualitative methods, the researchidentifies crucial dimensions in the management of organizational dynamics …

The Cultivation Of Eating Disorders Through Instagram, Kendall O'Brien

USF Tampa Graduate Theses and Dissertations

A profusion of research has been dedicated to the effects of new media on body image. In an attempt to explain the inflation of eating disorders, several researchers have turned to the cultivation theory, postulating that increased interaction with these medias will lead to internalizations of the messages they disseminate. The over presence of extremely thin models and actresses can create a new reality for media users, who begin to equate thinness with beauty, power, femininity and happiness. While an abundance of research has delved into the impact of this thin ideal through television and magazines, the Internet as a …

Neuroinflammatory Paradigms In Lysosomal Storage Diseases., Megan Bosch, Tammy Kielian

Journal Articles: Pathology and Microbiology

Lysosomal storage diseases (LSDs) include approximately 70 distinct disorders that collectively account for 14% of all inherited metabolic diseases. LSDs are caused by mutations in various enzymes/proteins that disrupt lysosomal function, which impairs macromolecule degradation following endosome-lysosome and phagosome-lysosome fusion and autophagy, ultimately disrupting cellular homeostasis. LSDs are pathologically typified by lysosomal inclusions composed of a heterogeneous mixture of various proteins and lipids that can be found throughout the body. However, in many cases the CNS is dramatically affected, which may result from heightened neuronal vulnerability based on their post-mitotic state. Besides intrinsic neuronal defects, another emerging factor common to …

The Wooster Voice (Wooster, Oh), 2015-10-30, Wooster Voice Editors

The Voice: 2012-Present

The Story of the Week in this issue of the Wooster Voice is "The Underground to remain closed until spring semester," noting extensive renovations delaying its opening. Other news articles in include "Papercut replaces Pharos system," referring to a change in printing software, "New full-time counselor hired at Wellness Center," "Scot Cottage residents allowed to move back into the building," and "Unknown man knock at several campus houses." In Features, the Voice looks at an Independent Study on the diversity of squirrels and service projects at Miller Manor. Other articles in this section include a delay in an Israel/Palestine trip, …

Analisis Kualitas Dan Kuantitas Tenaga Keperawatan Terhadap Persepsi Insiden Keselamatan Pasien Di Rs X Jakarta Tahun 2015, Evelyne Sumihar Friyanti

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Patient safety has become a very important issue in health care. Everyone wants to get health care that is safe and free from unwanted injuries. Through this study, analyzed the quality and quantity of nurse perceptions of patient safety incidents in the hospital X. The study was conducted on 44 nurses and midwives using cross sectional design to examine the relationship between the variables of knowledge, education, ease of use tools, work experience, discipline and the number of nurses on patient safety incidents.

Analisis Faktor-Faktor Yang Berhubungan Dengan Efektivitas Komunikasi Perawat Dan Pasien Di Ruang Rawat Inap Rumah Sakit Harapan Mulia Kabupaten Bekasi Tahun 2015, Prasetyaningtyas Agustrianti

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The study aims to determine the factors associated with the effectiveness of nurse and patient communication atinpatient unit in Harapan Mulia Hospitallocated in Bekasi Regency.It is a quantitative study with cross-sectional design.Samples are the total population amounted to 30 nurses with 60 patients as respondentsconducted in March - May 2015. The results showed that 53.3% of patients perceived that nurses’s communication was effective, further analysis with logistic regression showed no significant relationship between the characters nurses, physical and mental fatigue, language, leadership and management support for hospitals, facilities and reward with the nurses and patients communication effectiveness.

State V. Crotto Respondent's Brief Dckt. 42993

Not Reported

No abstract provided.

The Decision, Implementation And Assessment Of A Credit-Bearing Activity Class By Faculty In Residence: A Case Study, Janet Callahan, Geoff Harrison, Michael Humphrey, Cala Sielaff, Melissa Wintrow

Materials Science and Engineering Faculty Publications and Presentations

This case study reports on a programmatic decision to require a credit-bearing course that was made by Faculty in Residence (FIR), including its implementation and results over a two-year period from 2010-2012. The focus is on FIR and on the impact of their decision upon the students enrolled in their Living Learning Communities (LLCs). The credit-bearing course was a Kinesiology Activities class taken by all seven LLCs at Boise State University. Anonymous feedback from students was obtained via end of semester surveys; results were used to improve the course. Survey feedback was analyzed to assess the value students perceived to …

Skrining Fitokimia Cangkang Dan Kulit Batang Tanaman Jengkol Asal Ciamis Jawa Barat Sebagai Inisiasi Obat Diabetes Mellitus Berbahan Alam, Yudithia Maxiselly, Ade Ismail, Santi Rosniawaty, Intan Ratna Dewi Anjarsari

Jurnal Kultivasi

Pengembangan obat bahan alam semakin meningkat karena mempertimbangkan pola masyarakat yang kini lebih memilih hidup back to nature.Jengkol merupakan salah satu tanaman yang memiliki potensi sebagai obat bahan alam. Kandungan jengkol yang bermanfaat yaitu asam amino, vitamin, mineral, juga zat lain seperti saponin, flavonoid, dan tannin sangat dibutuhkan manusia. Potensi jengkol lainnya adalah mampu menurunkan kadar gula dalam darah sehingga dapat mencegah penyakit Diabetes Mellitus (DM). Bagian jengkol yang diteliti memiliki zat antidiabetes adalah kulit batang, cangkang buah dan bijinya. Penelitian ini bertujuan melihat kandungan fitokimia pada cangkang dan kuit batang jengkol asal Ciamis Jawa Baratyang telah berhasil dikoleksi oleh …

A Pilot Study Investigating The Utilization Of Crest Pads For Treatment Of Toe Callus And Ulceration (Presentation), Monica L. Melo Dnp, Rn, Acns-Bc, Cwocn, Cfcn, James Mccullough Md, Tricia S. Bernecker Phd, Msn, Rn, Acns-Bc, John J. Hong Md, Jane Scott Trumbauer

Patient Care Services / Nursing

No abstract provided.

Stable Isotope-Enabled Pathway Elucidation Of 2,4-Dinitroanisole Metabolized By Rhizobium Lichtii, Hunter W. Schroer, Kathryn L. Langenfeld, Xueshu Li, Hans Joachim Lehmler, Craig L. Just

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Recently developed military explosives are safer to handle, but more environmentally mobile, than traditional explosives. The new insensitive munitions, including 2,4-dinitroanisole (DNAN), have been sparsely studied, making the use of bacterial and/or plant-based remediation approaches unfeasible without further information about the transformation of these compounds. To that end, Rhizobium lichtii isolated from willow tree tissues were studied and observed to completely degrade 5 mg L-1 DNAN within 24 h in liquid media with added carbon and nitrogen. The use of DNAN, [13C6] DNAN, and [15N2] DNAN enabled the identification of 11 previously unknown metabolites resulting from sulfation, acetylation, and/or methylation …

The Murray Ledger And Times, October 30, 2015, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern Examines Size and Power of Tests of Hypotheses
• Georgia Southern Analyzes Awereness about Emerging Public Health Trends

Health Policy & Management News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Georgia Southern Analyzes Awareness about Emerging Public Health Trends

Biostatistics News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• Georgia Southern Examines Size and Power of Tests of Hypotheses

Scholar Athletes Recognized For Performance In The Classroom, Georgia Southern University

Athletics: News & Publications

• Scholar Athletes Recognized For Performance in the Classroom

Cbfa 2015 Business And Human Flourishing - A Holistic Visual Model, John Visser

Faculty Work Comprehensive List

The reputation and, to a lesser degree the practice of business, perhaps more than those of any other institution, suffer from the kind of reductionism that is the stepchild of dualistic and secular thinking. Some business-bashing is deserved, since some businesses operate in a very opportunistic ways, but much of it can be traced back to a misunderstanding of what business is and does. Unfortunately, once we have been fooled into thinking that life can be compartmentalized, and that we can wall off religious beliefs from the rest of life, and that our economic lives belong on the secular side …

Reginal Intercession And The Case Of Cristina, Convicted Murderer, Katherine Allocco

Medieval Feminist Forum: A Journal of Gender and Sexuality

In the winter of 1328-1329, Cristina, widow of Thomas Scot, potter of London, was convicted, imprisoned in Newgate and sentenced to hang for the crime of murdering her husband. Her execution was delayed due to her pregnancy. In January or February 1329, Cristina sent a letter to Isabella of France, queen mother, requesting a King’s pardon. On March 2, Edward III pardoned Cristina, at his mother’s request, through letters patent. It appears that Isabella, who had an established reputation as an intercessor for both personal petitions and general political appeals, had successfully interceded on Cristina’s behalf. Although medieval queens- both …

Modified Early Warning Score Effect In The Icu Patient Population, Anne Rabert Rn, Dha, Ccrn, Ne-Bc

Patient Care Services / Nursing

No abstract provided.

Arts In Medicine To Host Lunch And Learn Nov. 9, Adam Pope

Browse All News

No abstract provided.

Uab Researcher Awarded Nih Grant To Study Pathogenesis Of Thrombotic Microangiopathy, Staff

Browse All News

No abstract provided.

Chimes: October 30, 2015, Calvin College

Chimes

High participation for Food Day by Bethany Cok

Upperclassmen help harvest in the Community Garden by Alicia De Jong

Freelance journalist visits Calvin by Maddie Hughey

"Steve Jobs" a poignant portrait of an imperfect man by Nate Hunt

Holly Ellerbroek's moment of grace by Mark Peless

Could beer hold the key to saving the bees? by Michael Messina

Sesame Street and autism by Kelsey Powers

October 30, 2015, The Dakota Student

The Dakota Student

No abstract provided.

Kawm Ntawv Qib Siab Understanding The Psychosociocultural Educational Experiences Of Hmong American Undergraduates, Mariko M. Lin, Pa Her, Alberta M. Gloria

Journal of Southeast Asian American Education and Advancement

Using a psychosociocultural framework, this study examined the educational experiences of 85 Hmong American undergraduates attending a predominantly-White university. Differences in class standing indicated that upper-division students reported higher confidence in college-related tasks than their lower-division counterparts, yet the upper-division students perceived a less-welcoming university environment that was incongruent with their cultural values than the lower-division undergraduates. Peer support, college self-efficacy and cultural congruity were salient variables in understanding Hmong American undergraduate’s educational experiences. The study’s limitations, future research directions, and implications for college administrators and faculty are discussed.